CN2554181Y - Bio-chip for detecting pre-marital health index - Google Patents
Bio-chip for detecting pre-marital health index Download PDFInfo
- Publication number
- CN2554181Y CN2554181Y CN 02261903 CN02261903U CN2554181Y CN 2554181 Y CN2554181 Y CN 2554181Y CN 02261903 CN02261903 CN 02261903 CN 02261903 U CN02261903 U CN 02261903U CN 2554181 Y CN2554181 Y CN 2554181Y
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- marital
- detected
- health indicator
- biochip
- dot matrix
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- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The utility model relates to the field of biomedical technology, in particular to a biological chip which can carry out the detection of the indicators of pre-marital health. The utility model aims at providing the biological chip to overcome the shortcomings that the cost of the prior art is high, the quality is difficult to be ensured during large-scale production and the detection results are not accurate. The technical proposal of the utility model to achieve the above purpose is that the utility model includes an outer shell, a substrate and a dot-matrix which is arranged on the substrate; the utility model is characterized in that the outer shell is a separated type hollow shell body, a liquid absorbing layer is arranged at the bottom part of the outer shell, the substrate is arranged on the liquid absorbing layer, and a detection port which is corresponding to the dot-matrix is arranged at the upper part of the outer shell.
Description
Affiliated technical field:
The utility model relates to field of biomedicine technology, is specifically related to a kind of biochip that pre-marital health indicator is detected.
Background technology:
The structure of biochip generally is to comprise base material and the detection molecules dot matrix that is fixed on the base material at present, its base material adopts sheet glass to make, a large amount of detection molecules are fixed on this glass baseplate by in-situ polymerization, there is following shortcoming in it: 1. higher because of detection molecules density on it, therefore the cost of manufacture height is difficult to during scale operation ensure the quality of products; 2. disposable assembling is finished, and waste product can't utilize once more, has increased material cost; 3. the test solution infiltration is inhomogeneous, and detected result is inaccurate.
Summary of the invention:
The purpose of this utility model provides a kind of biochip that pre-marital health indicator is detected, and is difficult to ensure the quality of products and the inaccurate shortcoming of detected result when overcoming prior art cost height, scale operation.
For achieving the above object, the technical solution of the utility model is: a kind of biochip that pre-marital health indicator is detected, comprise the dot matrix 3 on shell 1, base material 5 and the base material 5, its special character is, described shell 1 is split type hollow shell, shell 1 bottom is provided with liquid-adsorption layer 6, and base material 5 is arranged on the liquid-adsorption layer 6, and shell 1 top is provided with and dot matrix 3 corresponding detections mouths 2.
Above-mentioned shell 1 is made of two portions, comprises the drain pan 8 that is provided with liquid-adsorption layer 6 and base material 5 and be provided with detecting mouthfuls 2 loam cake 7, is convenient to change content like this.
Above-mentioned detection mouth 2 is one or more, corresponding to one or more dot matrix 3, can avoid the cross infection of disease indicators like this.
Above-mentioned base material 5 is nitrocellulose membranes, and described liquid-adsorption layer 6 is absorbent wool, thieving paper or macromolecule water uptake synthetic materials.Nitrocellulose membrane is a kind of millipore filtration, and it has stronger diafiltration, concentrated, agglutination, and detection can be carried out fast, improves the accuracy that detects, and the use of liquid-adsorption layer 6 can make the test solution infiltration evenly, can improve the accuracy of detection equally.
Side-lowers are provided with protruding eaves 4 in the above-mentioned detection mouth 2, influence detected result in order to stop test solution side leakage current to be gone in the housing.
Above-mentioned shell 1 bottom is provided with breather hole 9 corresponding to detecting mouth 2, can guarantee the infiltration of tested liquid like this, improves detection efficiency.
Above-mentioned dot matrix 3 is square several, and the point of sample number on each dot matrix 3 equates and is square several.
Above-mentioned dot matrix 3 is arranged as square.
Albumen on the above-mentioned dot matrix 3 can be two or more in bow type worm, hsv, chlamydia trachomatis, the Ureaplasma urealyticum associated protein in the pre-marital health indicator.
Albumen in the above-mentioned dot matrix 3 can be full bacterium or viral protein, wherein in some specific genes or polypeptide fragment albumen, corresponding full bacterium or the antibody protein of viral protein, corresponding some specific genes or the proteic monoclonal antibody albumen of polypeptide fragment a kind of, two or more.
Compared with prior art, the utility model has the advantages that: low cost of manufacture, quality can be protected during scale operation, and quick when detecting, accurate.
Description of drawings:
Fig. 1 is a structural representation of the present utility model;
Fig. 2 is the A-A sectional view of Fig. 1;
Fig. 3 is that the B of Fig. 1 is to view;
Fig. 4 is the rear view of Fig. 1.
Embodiment:
Below in conjunction with accompanying drawing the utility model is done and to be described in further detail.
Referring to Fig. 1～4, the utility model comprises the dot matrix 3 on shell 1, base material 5 and the base material 5, said shell 1 is split type hollow shell, constitute by the drain pan 8 that is provided with base material 5 and liquid-adsorption layer 6 and loam cake 7 two portions that are provided with detection mouth 2, liquid-adsorption layer 6 is arranged at the bottom of drain pan 8, base material 5 is arranged on the liquid-adsorption layer 6, and said loam cake 7 tops are provided with one of dot matrix 3 corresponding orthogonal and detect mouth 2.Said base material 5 is nitrocellulose membranes, and said liquid-adsorption layer 6 is absorbent wools.Said detection mouthful 2 interior side-lowers are provided with protruding eaves 4, and drain pan 8 bottoms corresponding with detecting mouthful 2 positions are provided with breather hole 9.
Dot matrix 3 on the said base material 5 is 4, is arranged as square, and the point of sample number on each dot matrix is 81, be arranged as square, on 4 dot matrix, be integrated with bow type worm respectively, hsv, chlamydia trachomatis, Ureaplasma urealyticum, used albumen are each index specific proteinses.On each dot matrix, whether desirable one arranges 9 as the Quality Control point range, effective in order to judge chip; Other gets one and arranges 9 as the data refer point range, in order to judge the reference of detected result; Left point on each dot matrix in this example is 63, as point range to be detected, detects the back in order to do contrast with the data refer point range, judges that detected result is positive or negative.
Claims (10)
1, a kind of biochip that pre-marital health indicator is detected, comprise the dot matrix (3) on shell (1), base material (5) and the base material (5), it is characterized in that: described shell (1) is split type hollow shell, shell (1) bottom is provided with liquid-adsorption layer (6), base material (5) is arranged on the liquid-adsorption layer (6), and shell (1) top is provided with and the corresponding detection of dot matrix (3) mouthful (2).
2, a kind of biochip that pre-marital health indicator is detected as claimed in claim 1, it is characterized in that: described shell (1) is made of two portions, comprises the drain pan (8) that is provided with liquid-adsorption layer (6) and base material (5) and is provided with the loam cake (7) that detects mouthful (2).
3, a kind of biochip that pre-marital health indicator is detected as claimed in claim 1 is characterized in that: described detection mouthful (2) is one or more.
4, as claim 1 or 2 or 3 described a kind of biochips that pre-marital health indicator is detected, it is characterized in that: described base material (5) is a nitrocellulose membrane, and described liquid-adsorption layer (6) is an absorbent wool, thieving paper or macromolecule water uptake synthetic materials.
5, a kind of biochip that pre-marital health indicator is detected as claimed in claim 4 is characterized in that: described detection mouthful (a 2) interior side-lower is provided with protruding eaves (4).
6, a kind of biochip that pre-marital health indicator is detected as claimed in claim 5 is characterized in that: described shell (1) bottom is provided with breather hole (9) corresponding to detecting mouthful (2).
7, a kind of biochip that pre-marital health indicator is detected as claimed in claim 6 is characterized in that: described dot matrix (3) is square several, and the point of sample number on each dot matrix (3) equates and is square several.
8, a kind of biochip that pre-marital health indicator is detected as claimed in claim 7, it is characterized in that: described dot matrix (3) is arranged as square.
9, a kind of biochip that pre-marital health indicator is detected as claimed in claim 6 is characterized in that: the albumen on the described dot matrix (3) is two or more in bow type worm, hsv, chlamydia trachomatis, the Ureaplasma urealyticum associated protein in the pre-marital health indicator.
10, a kind of biochip that pre-marital health indicator is detected as claimed in claim 7 is characterized in that: the albumen in the described dot matrix (3) be full bacterium or viral protein, wherein in some specific genes or polypeptide fragment albumen, corresponding full bacterium or the antibody protein of viral protein, corresponding some specific genes or the proteic monoclonal antibody albumen of polypeptide fragment a kind of, two or more.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02261903 CN2554181Y (en) | 2002-07-01 | 2002-07-01 | Bio-chip for detecting pre-marital health index |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02261903 CN2554181Y (en) | 2002-07-01 | 2002-07-01 | Bio-chip for detecting pre-marital health index |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN2554181Y true CN2554181Y (en) | 2003-06-04 |
Family
ID=33728578
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 02261903 Expired - Fee Related CN2554181Y (en) | 2002-07-01 | 2002-07-01 | Bio-chip for detecting pre-marital health index |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN2554181Y (en) |
-
2002
- 2002-07-01 CN CN 02261903 patent/CN2554181Y/en not_active Expired - Fee Related
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ASS | Succession or assignment of patent right |
Owner name: SHANGHAI CHUANGYUE BIOLOGY SCIENCE CO., LTD. Free format text: FORMER OWNER: XI AN POTOMAC BIO-TECHNOLOGY CO., LTD. Effective date: 20060901 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20060901 Address after: 200233, building 4, 3, Zhongjiang Road, 879, Shanghai, Putuo District Patentee after: Shanghai creation Biotechnology Co., Ltd. Address before: 710075 No. four, No. 23, hi tech Road, Shaanxi, Xi'an Patentee before: Xi'an Lian'er Biotechnology Co., Ltd. |
|
| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |