CN2565839Y - Biochip for proceeding detection of immune sterility index - Google Patents
Biochip for proceeding detection of immune sterility index Download PDFInfo
- Publication number
- CN2565839Y CN2565839Y CN 02261898 CN02261898U CN2565839Y CN 2565839 Y CN2565839 Y CN 2565839Y CN 02261898 CN02261898 CN 02261898 CN 02261898 U CN02261898 U CN 02261898U CN 2565839 Y CN2565839 Y CN 2565839Y
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- index
- biochip
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- detected
- shell
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Abstract
The utility model relates to the technical field of biomedicine, particularly relates to a biochip for detecting immune sterile indexes. The purpose of the utility model is to provide a biochip to overcome the disadvantages of high manufacturing cost, difficult quality guarantee during large-scale production and poor detecting accuracy easily caused by non-uniform penetration of the detected liquid of the prior art. The utility model has the technical proposal that the biochip comprises a casing, base material and a dot matrix arranged on the base material. The utility model is characterized in that the base material is a nitrocellulose film, and the casing is a hollow casing body. A liquid sucking layer and the base material are arranged in the casing, the liquid sucking layer is arranged at the bottom of the casing, the upper part of the casing is provided with a dot liquid mouth which corresponds to the dot matrix arranged on the base material, and the bottom of the casing is provided with an air ventilating hole which corresponds to the dot liquid mouth.
Description
Affiliated technical field:
The utility model relates to field of biomedicine technology, is specifically related to a kind of biochip that the immunological infertility index is detected.
Background technology:
The structure of biochip generally all comprises base material and the detection molecules dot matrix that is fixed on the base material, its base material adopts sheet glass to make, a large amount of detection molecules are fixed on this glass baseplate by in-situ polymerization, are difficult to when existing cost height, scale operation ensure the quality of products, because of the inhomogeneous defective that easily causes the detection accuracy difference of test solution infiltration.
The utility model content:
The purpose of this utility model provides a kind of biochip that the immunological infertility index is detected, and to overcome prior art manufacturing cost height, is difficult to ensure the quality of products the shortcoming of detection accuracy difference during scale operation.
For achieving the above object, technical solution of the present utility model is: a kind of biochip that the immunological infertility index is detected, comprise the dot matrix 4 on shell 1, base material 6 and the base material 6, its special character is, described base material 6 is nitrocellulose membranes, described shell 1 is a hollow shell, be provided with liquid-adsorption layer 7 and base material 6 in this shell 1, liquid-adsorption layer 7 is arranged at shell 1 bottom, shell 1 top be provided with base material 6 on 4 corresponding somes liquid mouths 2 of dot matrix, shell 1 bottom is provided with breather hole 5 corresponding to a liquid mouth 2.
Above-mentioned some liquid mouth 2 can be one or more.When being provided with a plurality of somes liquid mouths 2, each some liquid mouth 2 corresponding one or more dot matrix 4 can be avoided disease indicators cross infection each other like this.
Side-lower is provided with protruding eaves 8 in the above-mentioned some liquid mouth 2, goes in the housing in order to stop test solution side leakage current, and influences detected result.
Above-mentioned shell 1 top is provided with tag slot 3 near a side of putting liquid mouth 2, and this tag slot 3 is used for chip is carried out mark.
Above-mentioned liquid-adsorption layer 7 is absorbent wool, thieving paper or macromolecule water uptake synthetic materials.The test solution infiltration evenly can make and react carry out more complete when detecting, and improves the accuracy that detects.
Above-mentioned shell 1 is made of two portions clamping, comprises the drain pan 10 that a loam cake of liquid mouth 29 is arranged and be provided with liquid-adsorption layer 7 and base material 6 is set, and is convenient to dismounting.
Above-mentioned dot matrix 4 is square several, and the point of sample number on each dot matrix 4 equates and is square several.
Above-mentioned dot matrix 4 is arranged as square.
Albumen on the above-mentioned dot matrix 4 can be two or more in antisperm antibody in the immunological infertility index, AEA, anticardiolipin antibody, AOAb and the anti-hcg antibody relative specific albumen.
Albumen in the above-mentioned dot matrix 4 can be in each index specific proteins or wherein some specific genes or the polypeptide fragment albumen a kind of, two or more.
Compared with prior art, the utility model has the advantages that: low cost of manufacture, quality can be protected during scale operation, and makes the test solution infiltration evenly because of being provided with breather hole when detecting, and the whole testing process time is short, can reliably guarantee the accurate of detected result.
Description of drawings:
Fig. 1 is a structural representation of the present utility model;
Fig. 2 is the rear view of Fig. 1;
Fig. 3 is the A-A sectional view of Fig. 1;
Fig. 4 is that the B of Fig. 1 is to view.
Description of reference numerals is as follows:
The 1-shell, 2-point liquid mouth, 3-tag slot, 4-dot matrix, 5-breather hole, 6-base material, 7-liquid-adsorption layer, the protruding eaves of 8-, 9-loam cake, 10-drain pan.
Embodiment:
Below in conjunction with accompanying drawing the utility model is done and to be described in further detail.
Referring to Fig. 1～4, a kind of biochip that the immunological infertility index is detected, comprise shell 1, dot matrix 4 on base material 6 and the base material 6, described shell 1 adopts hollow shell, this shell 1 is made of two portions, comprise loam cake 9 and drain pan 10, clamping between two portions, be provided with the liquid-adsorption layer 7 of absorbent wool making and the base material 6 of cellulose nitrate film production in the drain pan 10, liquid-adsorption layer 7 is arranged at drain pan 10 bottoms, loam cake 9 tops be provided with base material 6 on 4 corresponding somes liquid mouths 2 of dot matrix, shell 1 bottom is provided with breather hole 5 corresponding to a liquid mouth 2, above said some liquid mouth 2 be one, side-lowers are provided with protruding eaves 8 in this liquid mouth 2, said shell 1 top is provided with tag slot 3 near a side of some liquid mouth 2.
Claims (10)
1, a kind of biochip that the immunological infertility index is detected, comprise the dot matrix (4) on shell (1), base material (6) and the base material (6), it is characterized in that: described base material (6) is a nitrocellulose membrane, described shell (1) is a hollow shell, be provided with liquid-adsorption layer (7) and base material (6) in this shell (1), liquid-adsorption layer (7) is arranged at shell (1) bottom, shell (1) top be provided with base material (6) on corresponding some liquid mouth of dot matrix (4) (2), shell (1) bottom is provided with breather hole (5) corresponding to a liquid mouth (2).
2, a kind of biochip that the immunological infertility index is detected as claimed in claim 1, it is characterized in that: described some liquid mouth (2) is one or more.
3, a kind of biochip that the immunological infertility index is detected as claimed in claim 1 is characterized in that: the interior side-lower of described some liquid mouth (2) is provided with protruding eaves (8).
4, as claim 1 or 2 or 3 described a kind of biochips that the immunological infertility index is detected, it is characterized in that: described shell (1) top is provided with tag slot (3) near a side of putting liquid mouth (2).
5, a kind of biochip that the immunological infertility index is detected as claimed in claim 4 is characterized in that: described liquid-adsorption layer (7) is absorbent wool, thieving paper or macromolecule water uptake synthetic materials.
6, a kind of biochip that the immunological infertility index is detected as claimed in claim 5, it is characterized in that: described shell (1) is made of two portions clamping, and comprising being provided with has the loam cake (9) of a liquid mouth (2) and be provided with liquid-adsorption layer (7) and the drain pan (10) of base material (6).
7, a kind of biochip that the immunological infertility index is detected as claimed in claim 6 is characterized in that: described dot matrix (4) is square several, and the point of sample number on each dot matrix (4) equates and is square several.
8, a kind of biochip that the immunological infertility index is detected as claimed in claim 7, it is characterized in that: described dot matrix (4) is arranged as square.
9, a kind of biochip that the immunological infertility index is detected as claimed in claim 8 is characterized in that: the albumen on the described dot matrix (4) be in antisperm antibody in the immunological infertility index, AEA, anticardiolipin antibody, AOAb and the anti-hcg antibody relative specific proteic two or more.
10, a kind of biochip that the immunological infertility index is detected as claimed in claim 9 is characterized in that: the albumen in the described dot matrix (4) be in each index specific proteins or wherein some specific genes or the polypeptide fragment albumen a kind of, two or more.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02261898 CN2565839Y (en) | 2002-07-01 | 2002-07-01 | Biochip for proceeding detection of immune sterility index |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02261898 CN2565839Y (en) | 2002-07-01 | 2002-07-01 | Biochip for proceeding detection of immune sterility index |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN2565839Y true CN2565839Y (en) | 2003-08-13 |
Family
ID=33728573
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 02261898 Expired - Fee Related CN2565839Y (en) | 2002-07-01 | 2002-07-01 | Biochip for proceeding detection of immune sterility index |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN2565839Y (en) |
-
2002
- 2002-07-01 CN CN 02261898 patent/CN2565839Y/en not_active Expired - Fee Related
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ASS | Succession or assignment of patent right |
Owner name: SHANGHAI CHUANGYUE BIOLOGY SCIENCE CO., LTD. Free format text: FORMER OWNER: XI AN POTOMAC BIO-TECHNOLOGY CO., LTD. Effective date: 20060901 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20060901 Address after: 200333, building 4, 3, Zhongjiang Road, 879, Shanghai, Putuo District Patentee after: Shanghai creation Biotechnology Co., Ltd. Address before: 710075 No. four, No. 23, hi tech Road, Shaanxi, Xi'an Patentee before: Xi'an Lian'er Biotechnology Co., Ltd. |
|
| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |