CN2554179Y - Bio-chip for detecting good birth and good care index - Google Patents
Bio-chip for detecting good birth and good care index Download PDFInfo
- Publication number
- CN2554179Y CN2554179Y CN 02261901 CN02261901U CN2554179Y CN 2554179 Y CN2554179 Y CN 2554179Y CN 02261901 CN02261901 CN 02261901 CN 02261901 U CN02261901 U CN 02261901U CN 2554179 Y CN2554179 Y CN 2554179Y
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- prenatal
- detected
- biochip
- dot matrix
- care index
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Abstract
The utility model relates to the field of biomedical technology, in particular to a biological chip which can carry out the detection of the indicators of healthy birth and child care. The utility model aims at providing the biological chip to overcome the shortcomings that the reaction is not complete and the accuracy of the detection results of the prior art is poor; The technical proposal of the utility model to achieve the above purpose is that the utility model includes a hollow outer shell, a substrate which is arranged in the hollow outer shell and a dot-matrix which is arranged on the substrate; the utility model is characterized in that the interior of the outer shell is further provided with a reverse osmosis membrane and a liquid absorbing layer, the reverse osmosis membrane and the liquid absorbing layer are sequentially arranged at the lower part of the substrate, and a detection port which is corresponding to the dot-matrix on the substrate is arranged at the upper part of the outer shell.
Description
Affiliated technical field:
The utility model relates to field of biomedicine technology, is specifically related to a kind of biochip that the prenatal and postnatal care index is detected.
Background technology:
Biochip comprises sheet base and the detection molecules dot matrix that is fixed on the base material, and a large amount of detection molecules are fixed on this glass baseplate by in-situ polymerization.Existing chip exist reaction not exclusively, the shortcoming of detected result poor accuracy, this causes by following reason, the one, it is inhomogeneous that test solution adds the back infiltration, the 2nd, after reaction, infiltrated the test solution generation reverse osmosis phenomenon of liquid-adsorption layer and secondary response again.
Summary of the invention:
The purpose of this utility model provides a kind of biochip that the prenatal and postnatal care index is detected, and the prior art reaction is incomplete to overcome, the shortcoming of detected result poor accuracy.
For achieving the above object, the technical solution of the utility model is: a kind of biochip that the prenatal and postnatal care index is detected, comprise base material 5 in the hollow shell 1, shell 1 and the dot matrix 4 on the base material 5, its special character is, also be provided with anti-anti-seepage membrane 6 and liquid-adsorption layer 7 in the described shell 1, anti-anti-seepage membrane 6 and liquid-adsorption layer 7 are set in turn in base material 5 bottoms, shell 1 top be provided with base material 5 on dot matrix 4 corresponding detection mouths 2.
Above-mentioned shell 1 bottom is provided with breather hole 11 corresponding to detecting mouth 2, and the test solution infiltration is more even, thereby improves the accuracy of detected result.
Above-mentioned shell 1 upper surface is provided with tag slot 3 near a side that detects mouth 2, and this tag slot 3 is used for chip is carried out mark.
Above-mentioned base material 5 is nitrocellulose membranes, and described liquid-adsorption layer 7 is absorbent wool, thieving paper or macromolecule water uptake synthetic materials.
Side-lowers are provided with protruding eaves 8 in the above-mentioned detection mouth 2, influence detected result in order to stop test solution side leakage current to be gone in the housing.
Above-mentioned hollow casing 1 is made of two portions clamping, comprise be provided with detect mouthfuls 2 loam cake 9 and in establish the drain pan 10 of base material 5, anti-anti-seepage membrane 6 and liquid-adsorption layer 7, be convenient to dismounting.
Above-mentioned dot matrix 4 is square several, and the point of sample number on each dot matrix 4 equates and is square several.
Above-mentioned dot matrix 4 is arranged as square.
Albumen on the above-mentioned dot matrix 4 can be two or three in bow type worm, herpes simplex virus I, herpes simplex virus I I, cytomegalovirus, rubella virus, varicella zoster virus and the parvovirus associated protein in the prenatal and postnatal care index.
Albumen in the above-mentioned dot matrix 4 can be full bacterium or viral protein, wherein in some specific genes or polypeptide fragment albumen, corresponding full bacterium or the whole antibody albumen of viral protein, corresponding some specific genes or the proteic monoclonal antibody albumen of polypeptide fragment a kind of, two or more.
Compared with prior art, the utility model has the advantages that:
1, simple in structure, low cost of manufacture;
2, owing to be provided with liquid-adsorption layer and anti-anti-seepage membrane, and be provided with breather hole at outer casing bottom corresponding to detecting mouth, side-lower is provided with protruding eaves in detecting mouthful, more than these structures guaranteed all that test solution infiltrates evenly, so react completely, detected result is accurate;
2, the utility model is rational in infrastructure, and the test solution requirement is few, can reduce patient's misery.
Description of drawings:
Fig. 1 is a structural representation of the present utility model;
Fig. 2 is the A-A sectional view of Fig. 1;
Fig. 3 is that the B of Fig. 1 is to view;
Fig. 4 is the rear view of Fig. 1.
The accompanying drawing drawing is described as follows:
1-shell, 2-detect mouth, the 3-tag slot, and the 4-dot matrix, the 5-base material, 6-prevents anti-seepage membrane, 7-liquid-adsorption layer, the protruding eaves of 8-, 9-loam cake, 10-drain pan, 11-breather hole.
Embodiment:
Below in conjunction with accompanying drawing the utility model is done and to be described in further detail.
Referring to Fig. 1～4, a kind of biochip that the prenatal and postnatal care index is detected, include by loam cake 9 and drain pan 10 two portions and constitute hollow shell 1, in drain pan 10, be provided with the liquid-adsorption layer 7 that absorbent wool is made, the base material 5 of cellulose nitrate film production and be arranged at their anti-anti-seepage membranes 6 between the two, base material 5 is provided with dot matrix 4, said loam cake 9 be provided with base material 5 on corresponding one of dot matrix 4 detect mouthfuls 2, this detection mouthful 2 interior side-lowers are provided with protruding eaves 8, the bottom of said drain pan 10 is provided with breather hole 11 corresponding to detecting mouth 2, the upper surface of said loam cake 9 is provided with tag slot 3 near a side that detects mouth 2, this tag slot 3 is used for chip is carried out mark, for example sticks the sign bar of examinee's name.
Dot matrix 4 on the said base material 5 is 36, is arranged as square, and the point of sample number on each dot matrix 4 is 9, is arranged as square.Be that a class is integrated with bow type worm, herpes simplex virus I, herpes simplex virus I I, cytomegalovirus, rubella virus, varicella zoster virus and parvovirus associated protein respectively with 5 dot matrix 4 on 35 dot matrix 4 therein, used albumen is each index specific proteins, 1 dot matrix 4 in said every group of 5 dot matrix 4 is as the Quality Control point range, and 4 dot matrix 4 in addition are as point range to be detected; Remaining 1 dot matrix 4 is as the data refer point range.
Claims (10)
1, a kind of biochip that the prenatal and postnatal care index is detected, comprise base material (5) in the hollow casing (1), shell (1) and the dot matrix (4) on the base material (5), it is characterized in that: also be provided with anti-anti-seepage membrane (6) and liquid-adsorption layer (7) in the described shell (1), anti-anti-seepage membrane (6) and liquid-adsorption layer (7) are set in turn in base material (5) bottom, shell (1) top be provided with base material (5) on the corresponding detection mouth of dot matrix (4) (2).
2, a kind of biochip that the prenatal and postnatal care index is detected as claimed in claim 1 is characterized in that: described shell (1) bottom is provided with breather hole (11) corresponding to detecting mouthful (2).
3, a kind of biochip that the prenatal and postnatal care index is detected as claimed in claim 2 is characterized in that: described shell (1) upper surface is provided with tag slot (3) near a side that detects mouthful (2).
4, as claim 1 or 2 or 3 described a kind of biochips that the prenatal and postnatal care index is detected, it is characterized in that: described base material (5) is a nitrocellulose membrane, and described liquid-adsorption layer (7) is absorbent wool, thieving paper or macromolecule water uptake synthetic materials.
5, a kind of biochip that the prenatal and postnatal care index is detected as claimed in claim 4 is characterized in that: described detection mouthful (a 2) inboard is provided with protruding eaves (8).
6, a kind of biochip that the prenatal and postnatal care index is detected as claimed in claim 5, it is characterized in that: described shell (1) is made of two portions clamping, comprises being provided with the loam cake (9) that detects mouthful (2) and being provided with liquid-adsorption layer (7) and the drain pan (10) of base material (5).
7, a kind of biochip that the prenatal and postnatal care index is detected as claimed in claim 6 is characterized in that: described dot matrix (4) is square several, and the point of sample number on each dot matrix (4) equates and is square several.
8, a kind of biochip that the prenatal and postnatal care index is detected as claimed in claim 7, it is characterized in that: described dot matrix (4) is arranged as square.
9, a kind of biochip that the prenatal and postnatal care index is detected as claimed in claim 8 is characterized in that: the albumen on the described dot matrix (4) is two or more of associated protein in bow type worm, herpes simplex virus I, herpes simplex virus I I, cytomegalovirus, rubella virus, varicella zoster virus and the parvovirus.
10, a kind of biochip that the prenatal and postnatal care index is detected as claimed in claim 9 is characterized in that: the albumen in the described dot matrix (4) be full bacterium or viral protein, wherein in some specific genes or polypeptide fragment albumen, corresponding full bacterium or the whole antibody albumen of viral protein, corresponding some specific genes or the proteic monoclonal antibody albumen of polypeptide fragment a kind of, two or more.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02261901 CN2554179Y (en) | 2002-07-01 | 2002-07-01 | Bio-chip for detecting good birth and good care index |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02261901 CN2554179Y (en) | 2002-07-01 | 2002-07-01 | Bio-chip for detecting good birth and good care index |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN2554179Y true CN2554179Y (en) | 2003-06-04 |
Family
ID=33728576
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 02261901 Expired - Fee Related CN2554179Y (en) | 2002-07-01 | 2002-07-01 | Bio-chip for detecting good birth and good care index |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN2554179Y (en) |
-
2002
- 2002-07-01 CN CN 02261901 patent/CN2554179Y/en not_active Expired - Fee Related
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ASS | Succession or assignment of patent right |
Owner name: SHANGHAI CHUANGYUE BIOLOGY SCIENCE CO., LTD. Free format text: FORMER OWNER: XI AN POTOMAC BIO-TECHNOLOGY CO., LTD. Effective date: 20060901 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20060901 Address after: 200333, building 4, 3, Zhongjiang Road, 879, Shanghai, Putuo District Patentee after: Shanghai creation Biotechnology Co., Ltd. Address before: 710075 No. four, No. 23, hi tech Road, Shaanxi, Xi'an Patentee before: Xi'an Lian'er Biotechnology Co., Ltd. |
|
| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |