CN2867345Y

CN2867345Y - Biological chip for testing various pathogenic microorganism infective index

Info

Publication number: CN2867345Y
Application number: CN 200520079627
Authority: CN
Inventors: 陶东; 马卫今; 谢峰; 任跃军; 李治国
Original assignee: XI'AN LIANER TECHNOLOGY Co Ltd
Current assignee: XI'AN LIANER TECHNOLOGY Co Ltd
Priority date: 2005-11-02
Filing date: 2005-11-02
Publication date: 2007-02-07
Anticipated expiration: 2015-11-02

Abstract

The utility model relates to the technical field of biomedicine, specifically to a biochip for detecting various pathogenic microorganism infection indices. The utility model is to resolve problems existing in the prior art: poor judgment accuracy of test results and low operating safety. The biochip includes hollow shell, detection port, substrate equipped with lattice array and air vent, wherein rectangular groove is arranged on the shell bottom corresponding to the detection port, and the air vent is arranged inside the rectangular groove.

Description

A kind of biochip that various cause pathogeny imcrobe infection indexs are detected

Affiliated technical field:

The utility model relates to field of biomedicine technology, is specifically related to a kind of biochip that various cause pathogeny imcrobe infection indexs are detected.

Background technology:

Common biochip comprises a hollow casing that is fastened and connected at present, is test section in shell upper one side, and opposite side is the Handheld Division, and test section is provided with and detects mouth, is provided with antiskid groove on the Handheld Division in the certain structures.Its inner structure is generally: detect a mouthful correspondence position in the enclosure and be disposed with base material, anti-anti-seepage membrane and liquid-adsorption layer, dot matrix is set on the base material, the below of said shell inboard, detection mouth is provided with protruding eaves, is provided with bleeder vent corresponding to the outer casing bottom that detects mouth.The problem that this biochip exists is: 1, the testing result interpretation is inaccurate: outer casing bottom is the plane, it is sent into after the chip-reader and carriage bottom driving fit, hinder testing liquid and permeate the arrival liquid-adsorption layer downwards, often cause reaction too abundant like this on the base material because of testing liquid is more, so that the piebald phenomenon occurs, cause parallax error; 2, processing safety is low: can flow into enclosure because of more when testing liquid splashes into sometimes after detecting mouthful, even flow into and ooze out the Handheld Division; Drop in the outside because of misoperation has the part testing liquid sometimes when dropping liquid, flow of liquid is gone into the Handheld Division, and both of these case all might pollute operating personnel's hand, causes cross pollution, and processing safety is low.

Summary of the invention:

The utility model will overcome the inaccurate and low technical matters of processing safety of testing result interpretation that prior art exists.

For overcoming the problem that prior art exists, solution of the present utility model is: a kind of biochip that various cause pathogeny imcrobe infection indexs are detected, comprise hollow casing, detect mouthful 1, be provided with the base material 3 and the bleeder vent 6 of lattice array, its special character is, described outer casing bottom corresponding to detection mouth 1 is provided with rectangular recess 5, and described bleeder vent 6 is arranged in the rectangular recess 5.

The length direction of above-mentioned shell is provided with the conduction trough 4 that is communicated with rectangular recess 5.Strengthen air permeable effect.

Above-mentioned conduction trough 4 is arranged at respectively on the extended line on two limits of rectangular recess 5.Process more convenient.

Above-mentioned conduction trough 4 is arranged at a side that detects mouth 1 along the outer cover length direction.Avoid may the phenomenon of leakage taking place and operating personnel are constituted harm.

Be provided with anti-overflow ditch 2 around the above-mentioned detection mouth 1, above-mentioned enclosure is provided with dividing plate 7.The anti-overflow ditch can retain a spot of testing liquid, avoids testing liquid to enter the Handheld Division, and dividing plate is isolated Handheld Division and test section internally, can avoid inner unnecessary testing liquid to enter the Handheld Division.

Albumen on the above-mentioned lattice array can be more than three kinds or three kinds of various cause pathogeny imcrobe infection index associated protein.

Albumen on the above-mentioned lattice array be full bacterium or virus protein, wherein a certain special gene or polypeptide fragments albumen, corresponding full bacterium or virus protein antibody protein, wherein in the monoclonal antibody of a certain special gene or polypeptide fragments albumen more than three kinds or three kinds, two arrays of a side are the Quality Control array.

Compared with prior art, the utility model has the advantages that:

1, testing result interpretation accuracy rate improves: outer casing bottom is provided with rectangular recess and conduction trough, after sending into chip-reader, chip is difficult for driving fit with the carriage bottom, do not hinder testing liquid to permeate the arrival liquid-adsorption layer downwards, so just having guaranteed that the testing liquid on the base material evenly distributes reacts, and can not occur the piebald phenomenon again.

2, processing safety improves: when testing liquid during because of more inflow enclosure, dividing plate can be with its barrier at test section; Detect when mouthful outside when dropping liquid drops in, liquid can be temporarily stored in the anti-overflow ditch, and the utility model has thoroughly solved the problem that cross pollution takes place operating personnel.

3, the utility model is easy to manufacture, and processing technology changes easily on original structure, and quality can guarantee during large-scale production, so large-scale industrial production is easily realized.

4, applied widely: the detection that can be applicable to multiple disease.

Description of drawings:

Fig. 1 is a structural representation of the present utility model;

Fig. 2 is a polycrystalline substance synoptic diagram of the present utility model;

Fig. 3 is the A-A cut-open view of Fig. 2.

Description of reference numerals is as follows:

1---detect mouth, 2---the anti-overflow ditch, 3---base material, 4---conduction trough, 5---rectangular recess, 6---bleeder vent, 7---dividing plate.

Embodiment:

Below in conjunction with accompanying drawing the utility model is described in detail.

Referring to Fig. 1-3, the utility model comprises hollow casing, detection mouth 1, is provided with base material 3, rectangular recess 5 and the bleeder vent 6 of lattice array.Rectangular recess 5 is arranged at outer casing bottom corresponding to detecting mouth 1, and bleeder vent 6 is arranged in the rectangular recess 5.The length direction of said shell is provided with the conduction trough 4 that is communicated with rectangular recess 5, and this conduction trough 4 is arranged on the extended line on two limits of rectangular recess 5 respectively and is arranged in the test section.Around said detection mouth 1, be provided with anti-overflow ditch 2, be provided with dividing plate 7 in above-mentioned enclosure.

Lattice array on the described base material can be 12, it is 2 that each lattice array is counted, dot matrix is arranged as rectangle, wherein two arrays are the Quality Control array about the left side, all the other 10 dot matrix are classified more than three kinds or three kinds of associated protein more than three kinds or three kinds of various cause pathogeny imcrobe infection index associated protein as, after adding test solution, judge yin and yang attribute by the chip reading apparatus.The Quality Control array can be used as the important indicator whether biochip lost efficacy.

Claims

1, a kind of biochip that various cause pathogeny imcrobe infection indexs are detected, comprise hollow casing, detect mouthful (1), the base material (3) that is provided with lattice array and bleeder vent (6), it is characterized in that: described outer casing bottom corresponding to detection mouthful (1) is provided with rectangular recess (5), and described bleeder vent (6) is arranged in the rectangular recess (5).

2, a kind of biochip that various cause pathogeny imcrobe infection indexs are detected as claimed in claim 1, it is characterized in that: the length direction of described shell is provided with the conduction trough (4) that is communicated with rectangular recess (5).

3, a kind of biochip that various cause pathogeny imcrobe infection indexs are detected as claimed in claim 2 is characterized in that: described conduction trough (4) is arranged at respectively on the extended line on two limits of rectangular recess (5).

4, a kind of biochip that various cause pathogeny imcrobe infection indexs are detected as claimed in claim 3 is characterized in that: described conduction trough (4) is arranged at a side that detects mouthful (1) along the outer cover length direction.

5, as claim 1 or 4 described a kind of biochips that various cause pathogeny imcrobe infection indexs are detected, it is characterized in that: be provided with anti-overflow ditch (2) around the described detection mouthful (1), described enclosure is provided with dividing plate (7).