CN1988887A - 包含泊沙康唑的注射用药物混悬剂 - Google Patents

包含泊沙康唑的注射用药物混悬剂 Download PDF

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Publication number
CN1988887A
CN1988887A CNA2005800248542A CN200580024854A CN1988887A CN 1988887 A CN1988887 A CN 1988887A CN A2005800248542 A CNA2005800248542 A CN A2005800248542A CN 200580024854 A CN200580024854 A CN 200580024854A CN 1988887 A CN1988887 A CN 1988887A
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CN
China
Prior art keywords
formulation
posaconazole
mean
hour
further characterized
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2005800248542A
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English (en)
Chinese (zh)
Inventor
L·维奇－拉科什马南
S·乌格伍
V·桑德维斯
C·赫达洛
R·S·哈尔
G·克里希纳
Z·王
M·塔格列提
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme LLC
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34971355&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN1988887(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Corp filed Critical Schering Corp
Publication of CN1988887A publication Critical patent/CN1988887A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CNA2005800248542A 2004-05-28 2005-05-27 包含泊沙康唑的注射用药物混悬剂 Pending CN1988887A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US57512604P 2004-05-28 2004-05-28
US60/575,126 2004-05-28

Publications (1)

Publication Number Publication Date
CN1988887A true CN1988887A (zh) 2007-06-27

Family

ID=34971355

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2005800248542A Pending CN1988887A (zh) 2004-05-28 2005-05-27 包含泊沙康唑的注射用药物混悬剂

Country Status (15)

Country Link
EP (1) EP1761247A1 (enExample)
JP (1) JP2008501034A (enExample)
KR (1) KR20070027564A (enExample)
CN (1) CN1988887A (enExample)
AR (1) AR049063A1 (enExample)
AU (1) AU2005249502A1 (enExample)
CA (1) CA2567803A1 (enExample)
IL (1) IL179627A0 (enExample)
MX (1) MXPA06013886A (enExample)
NO (1) NO20066005L (enExample)
PE (1) PE20060291A1 (enExample)
RU (1) RU2006146555A (enExample)
TW (1) TWI290051B (enExample)
WO (1) WO2005117831A1 (enExample)
ZA (1) ZA200609890B (enExample)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102755628A (zh) * 2012-07-16 2012-10-31 中国科学院微生物研究所 一种抗真菌的药物组合物
CN102805731A (zh) * 2012-08-22 2012-12-05 北京莱瑞森医药科技有限公司 泊沙康唑干混悬剂及其制备方法
CN102958528A (zh) * 2010-06-29 2013-03-06 默沙东公司 取代β-环糊精稳定的泊沙康唑静脉输注液制剂
CN103284959A (zh) * 2012-02-22 2013-09-11 重庆圣华曦药业股份有限公司 泊沙康唑冻干粉针剂及制备方法
CN105030668A (zh) * 2015-06-26 2015-11-11 济川药业集团有限公司 泊沙康唑口服混悬剂及其制备方法
CN105997872A (zh) * 2016-07-08 2016-10-12 河南省立眼科医院 一种含有泊沙康唑的眼用纳米胶束抗真菌溶液
CN106333925A (zh) * 2015-07-10 2017-01-18 上海美悦生物科技发展有限公司 一种泊沙康唑液体混悬剂及其制备方法
CN110507609A (zh) * 2018-05-21 2019-11-29 上海医药工业研究院 泊沙康唑口服混悬剂的制备方法
CN111093373A (zh) * 2017-04-12 2020-05-01 V·J·班格万丁 组合物、包装的药物和使用泊沙康唑用于敏化抗性肿瘤的方法
CN111514146A (zh) * 2020-04-28 2020-08-11 山西振东泰盛制药有限公司 含有泊沙康唑的药物组合物

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060009469A1 (en) * 2004-05-28 2006-01-12 Leonore Witchey-Lakshmanan Particulate-stabilized injectable pharmacutical compositions of posaconazole
RS56044B1 (sr) * 2006-05-12 2017-09-29 Christian Noe Primena kombinovanih preparata koji sadrže antimikotike
EP2130540A1 (en) 2008-06-02 2009-12-09 Sandoz AG Pharmaceutical compositions containing a crystalline form of posaconazole
EP2141159A1 (en) 2008-07-03 2010-01-06 Sandoz AG A Crystalline form of posaconazole
EP2451805A1 (en) 2009-07-09 2012-05-16 Sandoz AG A crystalline form of posaconazole
WO2011144656A1 (en) 2010-05-19 2011-11-24 Sandoz Ag Preparation of posaconazole intermediates
WO2011144655A1 (en) 2010-05-19 2011-11-24 Sandoz Ag Process for the preparation of chiral hydrazides
CA2798010C (en) 2010-05-19 2018-09-25 Sandoz Ag Purification of posaconazole and of posaconazole intermediates
RU2585760C2 (ru) 2010-05-19 2016-06-10 Сандоз Аг Способ получения хиральных триазолонов
CN108329303A (zh) 2011-06-16 2018-07-27 桑多斯股份公司 制备手性化合物的方法
CN110582264B (zh) * 2017-03-26 2022-11-11 V·R·斯塔福德 眼睑皮肤状况的处理方法
CN113933131B (zh) * 2021-09-24 2024-01-26 合肥天一生物技术研究所有限责任公司 一种阴道微生物荧光染色液

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5091188A (en) * 1990-04-26 1992-02-25 Haynes Duncan H Phospholipid-coated microcrystals: injectable formulations of water-insoluble drugs
EP2090165A3 (en) * 2001-04-03 2012-03-28 Schering Corporation Antifungal composition with enhanced bioavailability

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102958528A (zh) * 2010-06-29 2013-03-06 默沙东公司 取代β-环糊精稳定的泊沙康唑静脉输注液制剂
CN103284959A (zh) * 2012-02-22 2013-09-11 重庆圣华曦药业股份有限公司 泊沙康唑冻干粉针剂及制备方法
CN103284959B (zh) * 2012-02-22 2015-06-03 重庆圣华曦药业股份有限公司 泊沙康唑冻干粉针剂及制备方法
CN102755628A (zh) * 2012-07-16 2012-10-31 中国科学院微生物研究所 一种抗真菌的药物组合物
CN102805731A (zh) * 2012-08-22 2012-12-05 北京莱瑞森医药科技有限公司 泊沙康唑干混悬剂及其制备方法
CN105030668A (zh) * 2015-06-26 2015-11-11 济川药业集团有限公司 泊沙康唑口服混悬剂及其制备方法
CN106333925B (zh) * 2015-07-10 2019-06-18 上海美悦生物科技发展有限公司 一种泊沙康唑液体混悬剂及其制备方法
CN106333925A (zh) * 2015-07-10 2017-01-18 上海美悦生物科技发展有限公司 一种泊沙康唑液体混悬剂及其制备方法
CN105997872B (zh) * 2016-07-08 2019-02-19 河南省立眼科医院 一种含有泊沙康唑的眼用纳米胶束抗真菌溶液
CN105997872A (zh) * 2016-07-08 2016-10-12 河南省立眼科医院 一种含有泊沙康唑的眼用纳米胶束抗真菌溶液
CN111093373A (zh) * 2017-04-12 2020-05-01 V·J·班格万丁 组合物、包装的药物和使用泊沙康唑用于敏化抗性肿瘤的方法
CN110507609A (zh) * 2018-05-21 2019-11-29 上海医药工业研究院 泊沙康唑口服混悬剂的制备方法
CN110507609B (zh) * 2018-05-21 2021-09-17 上海医药工业研究院 泊沙康唑口服混悬剂的制备方法
CN111514146A (zh) * 2020-04-28 2020-08-11 山西振东泰盛制药有限公司 含有泊沙康唑的药物组合物

Also Published As

Publication number Publication date
NO20066005L (no) 2007-02-27
EP1761247A1 (en) 2007-03-14
TWI290051B (en) 2007-11-21
RU2006146555A (ru) 2008-07-20
WO2005117831A1 (en) 2005-12-15
AR049063A1 (es) 2006-06-21
ZA200609890B (en) 2008-09-25
KR20070027564A (ko) 2007-03-09
PE20060291A1 (es) 2006-04-14
JP2008501034A (ja) 2008-01-17
TW200609001A (en) 2006-03-16
AU2005249502A1 (en) 2005-12-15
CA2567803A1 (en) 2005-12-15
IL179627A0 (en) 2007-05-15
MXPA06013886A (es) 2007-01-26

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