CN1960969B - 组胺h3受体药物、其制备方法及治疗用途 - Google Patents

组胺h3受体药物、其制备方法及治疗用途 Download PDF

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Publication number
CN1960969B
CN1960969B CN2005800171466A CN200580017146A CN1960969B CN 1960969 B CN1960969 B CN 1960969B CN 2005800171466 A CN2005800171466 A CN 2005800171466A CN 200580017146 A CN200580017146 A CN 200580017146A CN 1960969 B CN1960969 B CN 1960969B
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tetramethyleneimine
ylmethyl
ketone
biphenyl
fluoro
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Expired - Lifetime
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Chinese (zh)
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CN1960969A (zh
Inventor
L·S·比维斯
D·R·芬莱
T·P·芬恩
R·A·加德斯基
P·A·希普斯金德
W·J·霍巴克
C·D·杰苏达森
R·T·皮卡德
T·塔卡库瓦
G·M·沃特
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Eli Lilly and Co
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Eli Lilly and Co
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    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
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    • C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
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    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

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  • Neurology (AREA)
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  • Obesity (AREA)
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  • Urology & Nephrology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
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CN2005800171466A 2004-04-01 2005-03-25 组胺h3受体药物、其制备方法及治疗用途 Expired - Lifetime CN1960969B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US55854204P 2004-04-01 2004-04-01
US60/558,542 2004-04-01
US61710104P 2004-10-08 2004-10-08
US60/617,101 2004-10-08
PCT/US2005/010240 WO2005097740A1 (en) 2004-04-01 2005-03-25 Histamine h3 receptor agents, preparation and therapeutic uses

Publications (2)

Publication Number Publication Date
CN1960969A CN1960969A (zh) 2007-05-09
CN1960969B true CN1960969B (zh) 2012-03-28

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US (1) US7632857B2 (https=)
EP (1) EP1735278B1 (https=)
JP (1) JP4777974B2 (https=)
CN (1) CN1960969B (https=)
AT (1) ATE454372T1 (https=)
AU (1) AU2005230881B9 (https=)
BR (1) BRPI0509298A (https=)
CA (1) CA2561628C (https=)
CY (1) CY1109860T1 (https=)
DE (1) DE602005018758D1 (https=)
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MX (1) MXPA06011167A (https=)
PL (1) PL1735278T3 (https=)
PT (1) PT1735278E (https=)
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US7632857B2 (en) 2009-12-15
SI1735278T1 (sl) 2010-05-31
PT1735278E (pt) 2010-03-09
AU2005230881A1 (en) 2005-10-20
WO2005097740A1 (en) 2005-10-20
ES2337376T3 (es) 2010-04-23
JP4777974B2 (ja) 2011-09-21
MXPA06011167A (es) 2007-01-25
CA2561628C (en) 2012-05-08
AU2005230881B2 (en) 2011-03-31
CY1109860T1 (el) 2014-09-10
CN1960969A (zh) 2007-05-09
JP2007530698A (ja) 2007-11-01
AU2005230881B9 (en) 2011-08-25
PL1735278T3 (pl) 2010-06-30
BRPI0509298A (pt) 2007-09-18
US20070208024A1 (en) 2007-09-06
EP1735278A1 (en) 2006-12-27
ATE454372T1 (de) 2010-01-15
DK1735278T3 (da) 2010-04-12
CA2561628A1 (en) 2005-10-20
DE602005018758D1 (de) 2010-02-25

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