CN1951390B - 包含胶态二氧化硅的药物组合物 - Google Patents

包含胶态二氧化硅的药物组合物 Download PDF

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Publication number
CN1951390B
CN1951390B CN2006101159063A CN200610115906A CN1951390B CN 1951390 B CN1951390 B CN 1951390B CN 2006101159063 A CN2006101159063 A CN 2006101159063A CN 200610115906 A CN200610115906 A CN 200610115906A CN 1951390 B CN1951390 B CN 1951390B
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tablet
compositions
rapamycin
solid dispersion
pharmaceutical composition
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Expired - Lifetime
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CN2006101159063A
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Chinese (zh)
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CN1951390A (zh
Inventor
B·翰贝尔林
A·克拉默
S·霍伊尔丁
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Novartis AG
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Novartis AG
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    • AHUMAN NECESSITIES
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    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
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    • A61K9/145Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
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    • A61K9/2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Organic Chemistry (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Neurology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biomedical Technology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Hematology (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Urology & Nephrology (AREA)
CN2006101159063A 2001-09-28 2002-09-27 包含胶态二氧化硅的药物组合物 Expired - Lifetime CN1951390B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0123400.4A GB0123400D0 (en) 2001-09-28 2001-09-28 Organic compounds
GB0123400.4 2001-09-28

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CNA028190459A Division CN1561201A (zh) 2001-09-28 2002-09-27 包含胶态二氧化硅的药物组合物

Publications (2)

Publication Number Publication Date
CN1951390A CN1951390A (zh) 2007-04-25
CN1951390B true CN1951390B (zh) 2010-11-03

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ID=9922916

Family Applications (3)

Application Number Title Priority Date Filing Date
CN2006101159063A Expired - Lifetime CN1951390B (zh) 2001-09-28 2002-09-27 包含胶态二氧化硅的药物组合物
CN2010101174089A Pending CN101912392A (zh) 2001-09-28 2002-09-27 包含胶态二氧化硅的药物组合物
CNA028190459A Pending CN1561201A (zh) 2001-09-28 2002-09-27 包含胶态二氧化硅的药物组合物

Family Applications After (2)

Application Number Title Priority Date Filing Date
CN2010101174089A Pending CN101912392A (zh) 2001-09-28 2002-09-27 包含胶态二氧化硅的药物组合物
CNA028190459A Pending CN1561201A (zh) 2001-09-28 2002-09-27 包含胶态二氧化硅的药物组合物

Country Status (30)

Country Link
US (4) US20040254210A1 (https=)
EP (2) EP1432408B8 (https=)
JP (2) JP2005507897A (https=)
KR (1) KR100626785B1 (https=)
CN (3) CN1951390B (https=)
AR (2) AR036643A1 (https=)
AT (1) ATE485813T1 (https=)
BR (2) BRPI0212922B1 (https=)
CA (1) CA2458455C (https=)
CO (1) CO5390072A1 (https=)
CY (2) CY1111119T1 (https=)
DE (1) DE60238131D1 (https=)
DK (2) DK1432408T3 (https=)
EC (1) ECSP024323A (https=)
ES (2) ES2560106T3 (https=)
GB (1) GB0123400D0 (https=)
HU (1) HU229991B1 (https=)
IL (2) IL160498A0 (https=)
MX (1) MXPA04002814A (https=)
MY (1) MY150060A (https=)
NO (1) NO333892B1 (https=)
NZ (2) NZ542273A (https=)
PE (1) PE20030602A1 (https=)
PL (1) PL209704B1 (https=)
PT (2) PT2193788E (https=)
RU (1) RU2322970C2 (https=)
SI (1) SI1432408T1 (https=)
TW (1) TWI242449B (https=)
WO (1) WO2003028705A1 (https=)
ZA (1) ZA200401300B (https=)

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EP1568381A1 (en) * 2002-10-09 2005-08-31 Kyowa Hakko Kogyo Co., Ltd. Remedy for hormone-dependent cancer
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CN101444503B (zh) * 2008-12-31 2011-02-02 江苏大学 一种水飞蓟宾高效长效制剂及其制法
CN101439025B (zh) * 2008-12-31 2011-05-11 江苏大学 一种水飞蓟素高效长效制剂及其制法
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