CN1939335A - 使用β葡聚糖和抗体治疗癌性的方法 - Google Patents

使用β葡聚糖和抗体治疗癌性的方法 Download PDF

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Publication number
CN1939335A
CN1939335A CNA2006101362698A CN200610136269A CN1939335A CN 1939335 A CN1939335 A CN 1939335A CN A2006101362698 A CNA2006101362698 A CN A2006101362698A CN 200610136269 A CN200610136269 A CN 200610136269A CN 1939335 A CN1939335 A CN 1939335A
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China
Prior art keywords
glucan
tumor
cells
mice
soluble
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Pending
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CNA2006101362698A
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English (en)
Chinese (zh)
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戈登·D·罗斯
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University of Louisville Research Foundation ULRF
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University of Louisville Research Foundation ULRF
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=31978563&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN1939335(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by University of Louisville Research Foundation ULRF filed Critical University of Louisville Research Foundation ULRF
Publication of CN1939335A publication Critical patent/CN1939335A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/75—Agonist effect on antigen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
CNA2006101362698A 2002-09-04 2003-09-04 使用β葡聚糖和抗体治疗癌性的方法 Pending CN1939335A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40812602P 2002-09-04 2002-09-04
US60/408,126 2002-09-04

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN03824893XA Division CN1694715B (zh) 2002-09-04 2003-09-04 β葡聚糖和抗体在制备治疗癌性的药物中的用途

Publications (1)

Publication Number Publication Date
CN1939335A true CN1939335A (zh) 2007-04-04

Family

ID=31978563

Family Applications (3)

Application Number Title Priority Date Filing Date
CNA2006101362698A Pending CN1939335A (zh) 2002-09-04 2003-09-04 使用β葡聚糖和抗体治疗癌性的方法
CNB038248956A Ceased CN100363054C (zh) 2002-09-04 2003-09-04 全葡聚糖颗粒在抗癌药物中的应用
CN03824893XA Expired - Lifetime CN1694715B (zh) 2002-09-04 2003-09-04 β葡聚糖和抗体在制备治疗癌性的药物中的用途

Family Applications After (2)

Application Number Title Priority Date Filing Date
CNB038248956A Ceased CN100363054C (zh) 2002-09-04 2003-09-04 全葡聚糖颗粒在抗癌药物中的应用
CN03824893XA Expired - Lifetime CN1694715B (zh) 2002-09-04 2003-09-04 β葡聚糖和抗体在制备治疗癌性的药物中的用途

Country Status (9)

Country Link
US (3) US8883760B2 (https=)
EP (3) EP2181711A1 (https=)
JP (1) JP2006502167A (https=)
CN (3) CN1939335A (https=)
AT (1) ATE462437T1 (https=)
AU (2) AU2003295326A1 (https=)
CA (2) CA2496508C (https=)
DE (1) DE60331925D1 (https=)
WO (2) WO2004021994A2 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8563531B2 (en) 2002-08-13 2013-10-22 Biothera, Inc. Methods of using beta glucan as a radioprotective agent
US8883760B2 (en) 2002-09-04 2014-11-11 University Of Louisville Research Foundation, Inc. Cancer therapy using beta glucan and antibodies

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US8323644B2 (en) * 2006-01-17 2012-12-04 Sloan-Kettering Institute For Cancer Research Therapy-enhancing glucan
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8563531B2 (en) 2002-08-13 2013-10-22 Biothera, Inc. Methods of using beta glucan as a radioprotective agent
US8883760B2 (en) 2002-09-04 2014-11-11 University Of Louisville Research Foundation, Inc. Cancer therapy using beta glucan and antibodies
US9522187B2 (en) 2002-09-04 2016-12-20 University Of Louisville Research Foundation, Inc. Cancer therapy using beta glucan and antibodies

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WO2004030613A3 (en) 2005-01-13
EP1536820A2 (en) 2005-06-08
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CA2496508C (en) 2014-04-22
AU2003295326A1 (en) 2004-04-23
CA2496596A1 (en) 2004-03-18
EP1539194A4 (en) 2007-06-13
US8883760B2 (en) 2014-11-11
AU2003268486A1 (en) 2004-03-29
CN100363054C (zh) 2008-01-23
DE60331925D1 (de) 2010-05-12
JP2006502167A (ja) 2006-01-19
US20060009419A1 (en) 2006-01-12
US9522187B2 (en) 2016-12-20
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WO2004021994A3 (en) 2004-08-12
EP1536820A4 (en) 2007-06-20
CA2496596C (en) 2016-06-28
CN1694715A (zh) 2005-11-09
CN1697659A (zh) 2005-11-16
US20170056432A1 (en) 2017-03-02
EP1539194A2 (en) 2005-06-15
EP2181711A1 (en) 2010-05-05
EP1536820B2 (en) 2013-10-23
AU2003295326A8 (en) 2004-04-23
AU2003268486A8 (en) 2004-03-29
ATE462437T1 (de) 2010-04-15

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