CN1933815A - 用于预计量dpi的干粉制剂 - Google Patents

用于预计量dpi的干粉制剂 Download PDF

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Publication number
CN1933815A
CN1933815A CN200580009403.1A CN200580009403A CN1933815A CN 1933815 A CN1933815 A CN 1933815A CN 200580009403 A CN200580009403 A CN 200580009403A CN 1933815 A CN1933815 A CN 1933815A
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CN
China
Prior art keywords
preparation
dosage
dose
powder
container
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN200580009403.1A
Other languages
English (en)
Chinese (zh)
Inventor
T·尼尔松
C·弗里贝里
L·卡克斯
A·尼米
S·卡兰德
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mederio AG
Original Assignee
Mederio AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32105799&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN1933815(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Mederio AG filed Critical Mederio AG
Publication of CN1933815A publication Critical patent/CN1933815A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0046—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
    • A61M15/005—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged on a cylindrical surface
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Otolaryngology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
CN200580009403.1A 2004-03-29 2005-03-23 用于预计量dpi的干粉制剂 Pending CN1933815A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE04008447 2004-03-29
SE0400844A SE528121C2 (sv) 2004-03-29 2004-03-29 Preparering av torrpulver för på förhand uppmätt DPI

Publications (1)

Publication Number Publication Date
CN1933815A true CN1933815A (zh) 2007-03-21

Family

ID=32105799

Family Applications (1)

Application Number Title Priority Date Filing Date
CN200580009403.1A Pending CN1933815A (zh) 2004-03-29 2005-03-23 用于预计量dpi的干粉制剂

Country Status (15)

Country Link
US (1) US20050211244A1 (https=)
EP (1) EP1732515B1 (https=)
JP (1) JP2007530671A (https=)
CN (1) CN1933815A (https=)
AT (1) ATE399534T1 (https=)
AU (1) AU2005225335A1 (https=)
CA (1) CA2556443A1 (https=)
DE (1) DE602005007876D1 (https=)
DK (1) DK1732515T3 (https=)
ES (1) ES2311217T3 (https=)
MX (1) MXPA06009286A (https=)
RU (1) RU2006131829A (https=)
SE (1) SE528121C2 (https=)
WO (1) WO2005092289A1 (https=)
ZA (1) ZA200606963B (https=)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103287602A (zh) * 2013-06-27 2013-09-11 顺天保暖制品（昆山）有限公司 一种包装机上的分体式量杯
CN105828819A (zh) * 2014-04-08 2016-08-03 桑萨（巴巴多斯）公司 烟碱制剂及其制备方法
CN106539794A (zh) * 2015-09-16 2017-03-29 桑萨（巴巴多斯）公司 可吸入烟碱制剂以及其制备和使用方法
CN111278404A (zh) * 2017-09-21 2020-06-12 豪夫迈·罗氏有限公司 制药设施和药物产品的制造方法

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GB0327723D0 (en) 2003-09-15 2003-12-31 Vectura Ltd Pharmaceutical compositions
EP2402001A1 (en) * 2005-05-18 2012-01-04 Pulmatrix, Inc. Formulations for alteration of biophysical properties of mucosal lining
US20070101991A1 (en) * 2005-11-08 2007-05-10 Mederio Ag Optimizing release of dry medicament powder
DK1947010T3 (da) * 2005-11-21 2010-05-17 Mannkind Corp Pulverdoserings- og affølingsapparatur samt fremgagnsmåder
GB0616299D0 (en) * 2006-08-16 2006-09-27 Cambridge Consultants Drug Capsules for dry power inhalers
US7908992B2 (en) * 2007-01-09 2011-03-22 R.P. Scherer Technologies, Llc System and method for dusting soft capsules
CA2728808A1 (en) * 2008-02-01 2009-08-06 Vectura Limited Pulmonary formulations of triptans
PL2334560T3 (pl) 2008-08-05 2014-04-30 Mannkind Corp Moduły dozownika proszku i zespoły dozownika proszku
CA2754691C (en) 2009-03-26 2019-07-30 Pulmatrix, Inc. Dry powder formulations and methods for treating pulmonary diseases
GB0905840D0 (en) * 2009-04-06 2009-05-20 Sagentia Ltd Apparatus and methods
EP2464346A1 (en) 2010-08-30 2012-06-20 Pulmatrix, Inc. Treatment of cystic fibrosis using calcium lactate, leucine and sodium chloride in a respiraple dry powder
AU2011296343B2 (en) 2010-08-30 2015-12-10 Pulmatrix Operating Company, Inc. Dry powder formulations and methods for treating pulmonary diseases
RU2017144619A (ru) 2010-09-29 2019-02-20 Пулмэтрикс, Инк. Катионы одновалентных металлов сухих порошков для ингаляций
EP3470057B1 (en) 2010-09-29 2021-11-03 Pulmatrix Operating Company, Inc. Cationic dry powders comprising magnesium salt
CN107596518B (zh) 2012-02-29 2021-04-23 普马特里克斯营业公司 可吸入干粉剂
WO2014007772A2 (en) 2012-07-05 2014-01-09 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Inhalation compositions comprising glucose anhydrous
WO2014007771A2 (en) 2012-07-05 2014-01-09 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Inhalation compositions comprising muscarinic receptor antagonist
WO2014007770A2 (en) * 2012-07-05 2014-01-09 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Inhalation compositions comprising corticosteroid and sorbitol
JP6473738B2 (ja) 2013-04-01 2019-02-20 パルマトリックス，インコーポレイテッド チオトロピウム乾燥粉末
WO2016067252A1 (en) 2014-10-31 2016-05-06 Glaxosmithkline Intellectual Property Development Limited Powder formulation
US20170071248A1 (en) * 2015-09-16 2017-03-16 Sansa Corporation (Barbados) Inc. System and Method for Controlling the Harshness of Nicotine-Based Dry Powder Formulations
US10149844B2 (en) 2015-09-16 2018-12-11 Philip Morris Products S.A. Inhalable nicotine formulations, and methods of making and using thereof
EP3327409B1 (en) * 2016-11-29 2019-09-11 Mettler-Toledo GmbH Automated dosage-dispensing system for powdery substances, and method of ascertaining that the system is ready for operation
CA3075720A1 (en) * 2017-10-02 2019-04-11 Novartis Ag Method for preparing a pharmaceutical product
CN121221570A (zh) * 2019-11-06 2025-12-30 曼金德公司 氯法齐明的组合物，含它们的组合，它们的制备方法，含它们的用途和治疗方法

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US3860618A (en) * 1967-08-08 1975-01-14 Philip Saxton Hartley Chromone
US5192528A (en) * 1985-05-22 1993-03-09 Liposome Technology, Inc. Corticosteroid inhalation treatment method
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SK283569B6 (sk) * 1993-10-01 2003-09-11 Astra Aktiebolag Spôsob spracovania jemne deleného práškového liečiva, zariadenie na vykonávanie tohto spôsobu a aglomeráty vyrobené týmto spôsobom
SE9400462D0 (sv) * 1994-02-11 1994-02-11 Astra Ab Filling device
DK0969816T3 (da) * 1997-03-20 2005-03-14 Schering Corp Fremstilling af pulveragglomerater
HUP0203626A2 (en) * 1999-10-11 2003-02-28 Ml Lab Plc Medicament delivery device with moisture resistant coating
DE60025019T2 (de) * 1999-10-29 2006-08-24 Nektar Therapeutics, San Carlos Trockenpulverzusammensetzungen mit verbesserter dispersivität
ES2525087T5 (es) * 2000-05-10 2018-06-28 Novartis Ag Polvos basados en fosfolípidos para administración de fármacos
GB0014082D0 (en) * 2000-06-10 2000-08-02 Glaxo Group Ltd Method and apparatus for transferring a defined quantity of powder
SE516554C2 (sv) * 2000-08-31 2002-01-29 Microdrug Ag Uppmätt elektrodos
SE517227C2 (sv) * 2000-09-25 2002-05-14 Microdrug Ag Inhalator för torrt pulver med folieskärare
SE522558C2 (sv) * 2001-07-13 2004-02-17 Microdrug Ag Förfarande och anordning för styrning av överföring av elektriskt laddade partiklar av ett medicinskt pulver till en målarea på ett substratelement vid en dosutformningsprocess
US7931022B2 (en) * 2001-10-19 2011-04-26 Respirks, Inc. Method and apparatus for dispensing inhalator medicament
GB0202912D0 (en) * 2002-02-07 2002-03-27 Meridica Ltd Method and apparatus for introducing powder into a pocket
SE524990C2 (sv) * 2002-04-12 2004-11-09 Microdrug Ag Preparation av terapeutiskt torrt pulver samt förfarande för uppdelning och spridning i luft av medicinskt pulver
GB0225621D0 (en) * 2002-11-02 2002-12-11 Glaxo Group Ltd Medicament carrier

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103287602A (zh) * 2013-06-27 2013-09-11 顺天保暖制品（昆山）有限公司 一种包装机上的分体式量杯
CN105828819A (zh) * 2014-04-08 2016-08-03 桑萨（巴巴多斯）公司 烟碱制剂及其制备方法
CN106539794A (zh) * 2015-09-16 2017-03-29 桑萨（巴巴多斯）公司 可吸入烟碱制剂以及其制备和使用方法
CN106539794B (zh) * 2015-09-16 2020-05-15 菲利普莫里斯生产公司 可吸入烟碱制剂以及其制备和使用方法
CN111278404A (zh) * 2017-09-21 2020-06-12 豪夫迈·罗氏有限公司 制药设施和药物产品的制造方法
CN111278404B (zh) * 2017-09-21 2023-05-09 豪夫迈·罗氏有限公司 制药设施和药物产品的制造方法

Also Published As

Publication number Publication date
US20050211244A1 (en) 2005-09-29
EP1732515A1 (en) 2006-12-20
SE528121C2 (sv) 2006-09-05
ZA200606963B (en) 2007-11-28
ATE399534T1 (de) 2008-07-15
AU2005225335A1 (en) 2005-10-06
CA2556443A1 (en) 2005-10-06
SE0400844L (sv) 2005-09-30
WO2005092289A1 (en) 2005-10-06
DE602005007876D1 (de) 2008-08-14
RU2006131829A (ru) 2008-05-10
SE0400844D0 (sv) 2004-03-29
DK1732515T3 (da) 2008-11-10
JP2007530671A (ja) 2007-11-01
ES2311217T3 (es) 2009-02-01
EP1732515B1 (en) 2008-07-02
MXPA06009286A (es) 2007-03-07

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C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
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Open date: 20070321