JP2007530671A - 事前計量されるｄｐｉのための乾燥粉末調合剤 - Google Patents

事前計量されるｄｐｉのための乾燥粉末調合剤 Download PDF

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Publication number
JP2007530671A
JP2007530671A JP2007506106A JP2007506106A JP2007530671A JP 2007530671 A JP2007530671 A JP 2007530671A JP 2007506106 A JP2007506106 A JP 2007506106A JP 2007506106 A JP2007506106 A JP 2007506106A JP 2007530671 A JP2007530671 A JP 2007530671A
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Japan
Prior art keywords
dose
formulation
container
particles
dry powder
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Pending
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JP2007506106A
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English (en)
Japanese (ja)
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JP2007530671A5 (https=
Inventor
トーマス ニルソン、
クラエス フライベルク、
ラルス カックス、
アルフ ニーミ、
スヴェン カランダー、
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mederio AG
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Mederio AG
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32105799&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JP2007530671(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Mederio AG filed Critical Mederio AG
Publication of JP2007530671A publication Critical patent/JP2007530671A/ja
Publication of JP2007530671A5 publication Critical patent/JP2007530671A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0046—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
    • A61M15/005—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged on a cylindrical surface
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Otolaryngology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
JP2007506106A 2004-03-29 2005-03-23 事前計量されるｄｐｉのための乾燥粉末調合剤 Pending JP2007530671A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0400844A SE528121C2 (sv) 2004-03-29 2004-03-29 Preparering av torrpulver för på förhand uppmätt DPI
PCT/SE2005/000418 WO2005092289A1 (en) 2004-03-29 2005-03-23 Dry powder preparations for pre-metered dpi

Publications (2)

Publication Number Publication Date
JP2007530671A true JP2007530671A (ja) 2007-11-01
JP2007530671A5 JP2007530671A5 (https=) 2008-05-08

Family

ID=32105799

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007506106A Pending JP2007530671A (ja) 2004-03-29 2005-03-23 事前計量されるｄｐｉのための乾燥粉末調合剤

Country Status (15)

Country Link
US (1) US20050211244A1 (https=)
EP (1) EP1732515B1 (https=)
JP (1) JP2007530671A (https=)
CN (1) CN1933815A (https=)
AT (1) ATE399534T1 (https=)
AU (1) AU2005225335A1 (https=)
CA (1) CA2556443A1 (https=)
DE (1) DE602005007876D1 (https=)
DK (1) DK1732515T3 (https=)
ES (1) ES2311217T3 (https=)
MX (1) MXPA06009286A (https=)
RU (1) RU2006131829A (https=)
SE (1) SE528121C2 (https=)
WO (1) WO2005092289A1 (https=)
ZA (1) ZA200606963B (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010515460A (ja) * 2007-01-09 2010-05-13 アール．ピー． シェーラー テクノロジーズ インコーポレイテッド 軟カプセル剤の粉付けシステム及び方法
JP2022554352A (ja) * 2019-11-06 2022-12-28 マンカインド コーポレイション クロファジミンの組成物、それを含む組合せ、その調製プロセス、それを含む使用及び処置方法

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GB0327723D0 (en) 2003-09-15 2003-12-31 Vectura Ltd Pharmaceutical compositions
AU2006247077A1 (en) * 2005-05-18 2006-11-23 Pulmatrix Inc. Formulations for alteration of biophysical properties of mucosal lining
US20070101991A1 (en) * 2005-11-08 2007-05-10 Mederio Ag Optimizing release of dry medicament powder
DE602006012120D1 (de) * 2005-11-21 2010-03-25 Mannkind Corp Gerät und Verfahren zur Pulverausgabe und Messung
GB0616299D0 (en) * 2006-08-16 2006-09-27 Cambridge Consultants Drug Capsules for dry power inhalers
WO2009095684A1 (en) * 2008-02-01 2009-08-06 Vectura Limited Pulmonary formulations of triptans
CN103482090B (zh) 2008-08-05 2016-02-10 曼康公司 改进的粉末分配器模块及粉末分配器组件
ES2625260T5 (es) 2009-03-26 2020-07-29 Pulmatrix Operating Co Inc Formulaciones de polvo seco y métodos para el tratamiento de enfermedades pulmonares
GB0905840D0 (en) * 2009-04-06 2009-05-20 Sagentia Ltd Apparatus and methods
WO2012030645A1 (en) 2010-08-30 2012-03-08 Pulmatrix, Inc. Respirably dry powder comprising calcium lactate, sodium chloride and leucine
CN103200938B (zh) 2010-08-30 2018-07-31 普马特里克斯营业公司 干燥粉末配方及用于治疗肺部疾病的方法
BR112013007304B1 (pt) 2010-09-29 2021-12-14 Pulmatrix, Inc. Pós secos de cátion de metal monovalente para inalação
PT3470057T (pt) 2010-09-29 2021-12-03 Pulmatrix Operating Co Inc Pós secos catiónicos compreendendo sais de magnésio
CN107596518B (zh) 2012-02-29 2021-04-23 普马特里克斯营业公司 可吸入干粉剂
WO2014007770A2 (en) * 2012-07-05 2014-01-09 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Inhalation compositions comprising corticosteroid and sorbitol
US10111957B2 (en) 2012-07-05 2018-10-30 Arven Ilac Snayi ve Ticaret A.S. Inhalation compositions comprising glucose anhydrous
US10105316B2 (en) 2012-07-05 2018-10-23 Arven llac Sanayi Ve Ticaret A.S. Inhalation compositions comprising muscarinic receptor antagonist
AU2014248455B2 (en) 2013-04-01 2018-12-06 Pulmatrix Operating Company, Inc. Tiotropium dry powders
CN103287602A (zh) * 2013-06-27 2013-09-11 顺天保暖制品（昆山）有限公司 一种包装机上的分体式量杯
CA2944471C (en) * 2014-04-08 2020-03-31 Philip Morris Products S.A. Nicotine formulations and methods of making the same
MX392636B (es) 2014-10-31 2025-03-24 Glaxosmithkline Ip Dev Ltd Formulacion en polvo.
US9585835B1 (en) 2015-09-16 2017-03-07 Sansa Corporation (Barbados) Inc. Inhalable nicotine formulations and methods of making and using the same
US10149844B2 (en) 2015-09-16 2018-12-11 Philip Morris Products S.A. Inhalable nicotine formulations, and methods of making and using thereof
US20170071248A1 (en) * 2015-09-16 2017-03-16 Sansa Corporation (Barbados) Inc. System and Method for Controlling the Harshness of Nicotine-Based Dry Powder Formulations
EP3327409B1 (en) * 2016-11-29 2019-09-11 Mettler-Toledo GmbH Automated dosage-dispensing system for powdery substances, and method of ascertaining that the system is ready for operation
EP3684322B1 (en) * 2017-09-21 2022-04-20 F. Hoffmann-La Roche AG Pharmaceutical manufacturing installation and method of manufacturing of a pharmaceutical product
CA3075720A1 (en) * 2017-10-02 2019-04-11 Novartis Ag Method for preparing a pharmaceutical product

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GB9911770D0 (en) * 1999-05-21 1999-07-21 Glaxo Group Ltd Powder loading method
US3860618A (en) * 1967-08-08 1975-01-14 Philip Saxton Hartley Chromone
US5192528A (en) * 1985-05-22 1993-03-09 Liposome Technology, Inc. Corticosteroid inhalation treatment method
US6536427B2 (en) * 1990-03-02 2003-03-25 Glaxo Group Limited Inhalation device
US6794357B1 (en) * 1993-06-24 2004-09-21 Astrazeneca Ab Compositions for inhalation
PT721331E (pt) * 1993-10-01 2002-05-31 Astrazeneca Ab Processo i
SE9400462D0 (sv) * 1994-02-11 1994-02-11 Astra Ab Filling device
WO1998041193A1 (en) * 1997-03-20 1998-09-24 Schering Corporation Preparation of powder agglomerates
EP1240261B1 (en) * 1999-10-11 2004-02-18 Innovata Biomed Limited Medicament delivery device with moisture resistant coating
NZ518401A (en) * 1999-10-29 2004-01-30 Nektar Therapeutics Dry powder compositions having improved dispersivity
PT1280520E (pt) * 2000-05-10 2014-12-16 Novartis Ag Pós à base de fosfolípidos para administração de fármacos
GB0014082D0 (en) * 2000-06-10 2000-08-02 Glaxo Group Ltd Method and apparatus for transferring a defined quantity of powder
SE516554C2 (sv) * 2000-08-31 2002-01-29 Microdrug Ag Uppmätt elektrodos
SE517227C2 (sv) * 2000-09-25 2002-05-14 Microdrug Ag Inhalator för torrt pulver med folieskärare
SE522558C2 (sv) * 2001-07-13 2004-02-17 Microdrug Ag Förfarande och anordning för styrning av överföring av elektriskt laddade partiklar av ett medicinskt pulver till en målarea på ett substratelement vid en dosutformningsprocess
US7931022B2 (en) * 2001-10-19 2011-04-26 Respirks, Inc. Method and apparatus for dispensing inhalator medicament
GB0202912D0 (en) * 2002-02-07 2002-03-27 Meridica Ltd Method and apparatus for introducing powder into a pocket
SE524990C2 (sv) * 2002-04-12 2004-11-09 Microdrug Ag Preparation av terapeutiskt torrt pulver samt förfarande för uppdelning och spridning i luft av medicinskt pulver
GB0225621D0 (en) * 2002-11-02 2002-12-11 Glaxo Group Ltd Medicament carrier

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010515460A (ja) * 2007-01-09 2010-05-13 アール．ピー． シェーラー テクノロジーズ インコーポレイテッド 軟カプセル剤の粉付けシステム及び方法
JP2022554352A (ja) * 2019-11-06 2022-12-28 マンカインド コーポレイション クロファジミンの組成物、それを含む組合せ、その調製プロセス、それを含む使用及び処置方法

Also Published As

Publication number Publication date
ZA200606963B (en) 2007-11-28
WO2005092289A1 (en) 2005-10-06
EP1732515B1 (en) 2008-07-02
SE0400844D0 (sv) 2004-03-29
ATE399534T1 (de) 2008-07-15
AU2005225335A1 (en) 2005-10-06
CA2556443A1 (en) 2005-10-06
US20050211244A1 (en) 2005-09-29
EP1732515A1 (en) 2006-12-20
DK1732515T3 (da) 2008-11-10
ES2311217T3 (es) 2009-02-01
MXPA06009286A (es) 2007-03-07
SE528121C2 (sv) 2006-09-05
RU2006131829A (ru) 2008-05-10
DE602005007876D1 (de) 2008-08-14
SE0400844L (sv) 2005-09-30
CN1933815A (zh) 2007-03-21

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