CN1927361A - Nutritious health food for protecting liver and neutralizing the effect of alcohol and its preparation - Google Patents

Nutritious health food for protecting liver and neutralizing the effect of alcohol and its preparation Download PDF

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CN1927361A
CN1927361A CNA2006100103978A CN200610010397A CN1927361A CN 1927361 A CN1927361 A CN 1927361A CN A2006100103978 A CNA2006100103978 A CN A2006100103978A CN 200610010397 A CN200610010397 A CN 200610010397A CN 1927361 A CN1927361 A CN 1927361A
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alcohol
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陈福存
王德生
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Abstract

The invention relates to capsules and the process for preparation, wherein the raw materials include kudzuvine root, kudzuvine flower, hovenine, wild chrysanthemum flower, hyacinth bean, galangal rhizome, acanthopanax root, astragalus root, and composite vitamins.

Description

The nutritional health food of liver-protecting sobering up and preparation technology thereof
Affiliated field: the nutritional health food and the preparation technology thereof that the present invention relates to a kind of liver-protecting sobering up.
Background technology: present nutraceutical is more, the overall absorption weak effect, and edible not only inconvenience but also influence absorption, and existing processing technique is coarse, can not effectively discharge the ability of the complementation of multiple nutrients material, enriched nutritive effect.
Summary of the invention: the purpose of this invention is to provide a kind of absorption that helps the person, the liver protecting with health care and better nutritive validity is removed alcohol intoxication antifatigue nutritional health food.The objective of the invention is to be achieved through the following technical solutions: the present invention is a kind of nutritional health food of liver-protecting sobering up, the weight proportion of its component is: Radix Puerariae 300-350 restrains, Flos puerariae lobatae 300-350 restrains, Semen Hoveniae (Fructus Hoveniae) 800-900 restrains, Flos Chrysanthemi 400-500 restrains, Semen Lablab Album 200-300 restrains, Rhizoma Alpiniae Officinarum 100-150 restrains, Radix Et Caulis Acanthopanacis Senticosi 100-150 restrains,, Radix Astragali 100-150 restrains, vitamin B complex 200-250 restrains.
Preparation technology of the present invention is: (1) will clean after drying Radix Puerariae, Flos puerariae lobatae, Semen Hoveniae (Fructus Hoveniae), Flos Chrysanthemi, Semen Lablab Album, Rhizoma Alpiniae Officinarum, Radix Et Caulis Acanthopanacis Senticosi, the Radix Astragali, be mixed into mechanical activation comminution, granularity is controlled at about 20 orders, and mixed powder is put into basin, carries out enzymolysis processing, the water that adds 10 times of raw material weights earlier, adjust pH value scope 4.5----5.0, heat, add pectase 1.1% to 50----55 degree centigrade, proteinase-10 .7%, start agitator and be mixed, enzymolysis kept 4 hours, the middle stirring 1 time; (2) water is carried: raw material slag and enzymolysis solution directly are warmed up to 85----90 degree centigrade, kept 2.0----2.5 hour, coarse filtration: after raw material slag and extracting solution be cooled to room temperature, carry out screen cloth coarse filtration and filter cloth earlier and filter, the filtering residue list is put and is prepared enzymolysis and water extraction for the second time, for the first time filtrate to put into basin stand-by, same operation is advanced three times, both do the second time, extracted for the third time, again three lixiviating solution had been lumped together, carried out next procedure; (3) fine straining: with kieselguhr cardboard filter machine, above-mentioned three kinds of mixed extracts are carried out fine straining, getting filtrate, to put into basin stand-by, (4) vacuum and low temperature concentrates: use vacuum concentration pot, above-mentioned filtrate is concentrated, liquid relative density 1.15-1.18 (5) drying after concentrating: medicinal liquid is carried out spray drying, and inlet temperature is controlled at about 160 ℃, and leaving air temp is controlled at about 70 ℃; (6) mix: spray drying medicated powder is mixed with compound vitamin, adopt powerful V-Mixer mixing 15-20 branch.(7) capsule fill: the above-mentioned medicated powder that is mixed is adorned capsule with capsule filling machine, require capsule loading amount 0.25 gram/grain for qualified.
Formula combination of the present invention is novel unique, and China's excessive drinking in recent years and alcoholic are increasing, has a strong impact on stablizing of the healthy and family of people, society.Wine has pharmacological action widely to human body, and acute heavy drinking can cause nausea, vomiting, hypomnesis, absent minded, the impaired and emotional instability of fine movement ability, when serious even can cause death because of paralysis of respiratory muscle.The diseases such as can causing mental disorder, gastric ulcer and fatty liver, alcoholic hepatitis, liver cirrhosis of drinking for a long time, have rising that data shows esophageal carcinoma, onset of liver cancer rate as if also with drink relevant.Therefore develop the generally attention that the medicine that effectively relieves the effect of alcohol is subjected to the national governments and the people.The disintoxicating product of western countries' exploitation at present is based on synthetic, and Asian countries then stresses the research and development of natural plants.Ethanol is absorbed by digestive tract in human body, mainly at liver metabolism, is acetaldehyde through ethanol dehydrogenase (ADH) metabolism under physiological condition, and then is converted into acetic acid, enters the body circulation.In addition, the Michaelis constant (Km=8.6mmol/L) that also has the .MEOS of metabolism system such as (MEOS) of microsome Alcohol oxidase system in the liver mainly plays a role when picked-up high dose ethanol than the big several times of ADH (2mmol/L).Ethanol dehydrogenase also is found in gastrointestinal tract in recent years, but when taking a large amount of ethanol, it is insignificant that the gastrointestinal tract metabolism then seems.Ethanol brings out the generation of free radical in metabolic process, a plurality of organs such as liver are caused damage.Ethanol is fat-soluble bigger, can see through the blood brain barrier human brain, and its concentration and blood level difference in brain is little, therefore can infer intoxication according to concentration of alcohol in the blood.The antialcoholic approach will be exactly to reduce the concentration of ethanol patient's blood and metabolite thereof from the effect core of the medicine that relieves the effect of alcohol so.Alleviate its damage to each organ.According to ethanol metabolic characteristic in vivo.Current drug main will be from two aspects performance antialcoholism action.One, the gastrointestinal that suppresses ethanol absorbs, and strengthens ethanol at the gastrointestinal first pass effect, reduces the concentration of alcohol in the blood; Its two, medicine directly acts on hepatic metabolism enzyme system, the elimination speed of accelerating alcohol and metabolite thereof alleviates its infringement to tissue and cell.Careful liver antialcoholism capsule adopts primary raw materials such as pure natural raw material Flos puerariae lobatae, Radix Puerariae, Flos Chrysanthemi, Semen Hoveniae (Fructus Hoveniae), the Radix Astragali, through the refining effective component content height, the functional food of active ingredient enrichment of forming of processing technique such as biological enzymolysis breaking cellular wall, cryoconcentration.This product absorbs by the gastrointestinal that suppresses ethanol, strengthen ethanol at the gastrointestinal first pass effect, the concentration of alcohol accelerating alcohol in the reduction blood and the elimination speed of metabolite thereof, thereby reach adjustment, alleviation, remove the effect of the malaise symptoms that causes by drinking, avoiding the infringement of ethanol to liver simultaneously, is hobby alcohol user's good companion.Flos puerariae lobatae and Radix Puerariae are the most representative liver-protecting and alcoholism-relieving plants in the Chinese medicine.After the modern study reference took ethanol, Flos puerariae lobatae can effectively reduce concentration of alcohol in the blood.Domestic scholars is studied the health-care sobering product " Flos puerariae lobatae dew " based on Flos puerariae lobatae.In the Hepar Mus alcohol metabolism experiment in vitro, ethanol adds Flos puerariae lobatae dew, and to organize alcoholic acid metabolism amount be 13 times of simple ethanol group metabolism amount, and Flos puerariae lobatae can influence alcoholic acid gastrointestinal and absorb, and the prompting Flos puerariae lobatae can play a role in alcoholic acid absorption and two links of metabolism.The Japan scholar studies Flos puerariae lobatae ethanol is caused the influence that body metabolism is unusual.They separate the methanolic extract of Flos puerariae lobatae, and each effective site is carried out pharmacological research, find that wherein methanolic extract can suppress alcohol induced mouse blood sugar rising with the osajin composition that is contained in wherein; Methanolic extract and triterpene saponin constituents can suppress the rising of triglyceride in the blood; Isoflavone and triterpene saponin can also reduce the rising of the urinary nitrogen concentration that ethanol causes in addition.These results prove that the sober-up function of Flos puerariae lobatae is very definite.Japanese in addition scholar studies the theasaponin of known structure, finds that it can suppress alcoholic acid gastrointestinal and absorb, the ethanol that promotion has simultaneously absorbed and the elimination of acetaldehyde.People such as Takanli study the influence of green tea to alcohol metabolism, find that its crude extract can reduce mice and take the ethanol in the ethanol bleeding from anus and the concentration of acetaldehyde.Further experiment shows that the caffeine in the green tea has the effect similar to crude extract, and gallic acid epicatechin ester can resist the acetic acid that causes behind the alcohol metabolism and the rising of acetone, reduces acid concentration in the blood, alleviates side effect such as ataxia, liver injury.Natural plants such as modern pharmacological research Flos puerariae lobatae, tea all have and remove the free radical effect in the tangible body except that antialcoholism action.In chronic alcoholic liver disease and other various forms of toxic hepatic diseasies, noxious substance has important pathogenic effects at the free radical that intrahepatic metabolism produces.Excessive free radical can with cell membrane lipid, lipoprotein covalent bond, generate toxicants such as lipid peroxide, finally cause cell destroyed.This shows that these several natural Antialcoholic plants also have effect preferably aspect treatment ethanol and other toxic liver injuries.Process using multi-enzyme method technology, main with pectase, protease, Ye Huamei etc., make grain refine, the raw material yield is increased to 11.6-12.4%, adopt cryoconcentration to combine to make the effective ingredient still less product efficacy enhancing of running off simultaneously with drying process with atomizing, strengthen absorbing of the person, strengthen health food, health care and nutrition balance, this technology is the innovation of compatibility and new technology utilization.Do not appear in the newspapers at home through looking into newly, fill the domestic gaps real the genus.
The specific embodiment: the present invention is that a kind of the liver protecting is removed alcohol intoxication antifatigue nutritional health food, and the weight proportion of its component is a Radix Puerariae: 300-350 gram, Flos puerariae lobatae 300-350 gram, Semen Hoveniae (Fructus Hoveniae) 800-900 gram, Flos Chrysanthemi 400-500 gram, Semen Lablab Album 200-300 gram, Rhizoma Alpiniae Officinarum 100-150 gram, Radix Et Caulis Acanthopanacis Senticosi 100-150 gram, Radix Astragali 100-150 gram, vitamin B complex 200-250 gram.
Preparation technology of the present invention is: (1) will clean after drying Radix Puerariae, Flos puerariae lobatae, Semen Hoveniae (Fructus Hoveniae), Flos Chrysanthemi, Semen Lablab Album, Rhizoma Alpiniae Officinarum, Radix Et Caulis Acanthopanacis Senticosi, the Radix Astragali, be mixed into mechanical activation comminution, granularity is controlled at about 20 orders, and mixed powder is put into basin, carries out enzymolysis processing, the water that adds 10 times of raw material weights earlier, adjust pH value scope 4.5----5.0, heat, add pectase 1.1% to 50----55 degree centigrade, proteinase-10 .7%, start agitator and be mixed, enzymolysis kept 4 hours, the middle stirring 1 time; (2) water is carried: raw material slag and enzymolysis solution directly are warmed up to 85----90 degree centigrade, kept 2.0----2.5 hour, coarse filtration: after raw material slag and extracting solution be cooled to room temperature, carry out screen cloth coarse filtration and filter cloth earlier and filter, the filtering residue list is put and is prepared enzymolysis and water extraction for the second time, for the first time filtrate to put into basin stand-by, same operation is advanced three times, both do the second time, extracted for the third time, again three lixiviating solution had been lumped together, carried out next procedure; (3) fine straining: with kieselguhr cardboard filter machine, above-mentioned three kinds of mixed extracts are carried out fine straining, getting filtrate, to put into basin stand-by, (4) vacuum and low temperature concentrates: use vacuum concentration pot, above-mentioned filtrate is concentrated, liquid relative density 1.15-1.18 (5) drying after concentrating: medicinal liquid is carried out spray drying, and inlet temperature is controlled at about 160 ℃, and leaving air temp is controlled at about 70 ℃; (6) mix: spray drying medicated powder is mixed with compound vitamin, adopt powerful V-Mixer mixing 15-20 branch.(7) capsule fill: the above-mentioned medicated powder that is mixed is adorned capsule with capsule filling machine, require capsule loading amount 0.25 gram/grain for qualified.
Prescription of the present invention is main according to being " centre halfback No. 2002.51 " file of issuing of the Pharmacopoeia of the People's Republic of China, health ministry in the pertinent regulations, " Chinese health food progress " etc. that are the nutraceutical of polyphagia with emaciation medicine and health food, ad hoc meter formula for a product, main component research is as follows in the prescription:
One, Semen Lablab Album: Semen Lablab Album has another name called along the hedge bean, because of Rhizoma Euonymus (kind skin), plain boiled pork (cotyledon), white umbilicus are gained the name.The seed of drying and ripening is flat ellipse or flat oval, and long 0.8-1.3 centimetre, wide 0.6-0.9 centimetre, thick 0.7 centimetre, surperficial yellowish white or faint yellow.Semen Lablab Album is nutritious, and nutritive element contents such as its protein, calcium, phosphorus, ferrum occupy first place in vegetable.According to surveying and determination, the bright Semen Lablab Album of the heavy green grass or young crops of every hectogram contains protein 3 grams, fat 0.2 gram, and carbohydrate 5.6 grams, 123 milligrams of calcium, 77 milligrams in phosphorus, 0.9 milligram of ferrum, 0.58 milligram of carotene, 13 milligrams in ascorbic acid also has thiamine, riboflavin, nicotinic acid etc.Dried son boils in plain water, and to simmer soup agreeable to taste, is excellent tonic product, has a distinctive flavour with Fish are braised in soy sauce.Semen Lablab Album is also pharmaceutically acceptable using except that cooking.It is more than that the treatment cholera is told dysentery, grinds into powder with vinegar and obey it.Sector-style gas is controlled woman's leukorrhagia.Alcoholic intoxication, Fugu ocellatus ichthyotoxin, separate all vegetation poison, give birth to and chew and the liquor drink is got effect.Stopping leak dysentery is relieved summer heat, and warming the spleen and stomach except that damp and hot, is only quenched one's thirst.
Two, Semen Hoveniae (Fructus Hoveniae): having another name called Semen Hoveniae (Fructus Hoveniae), be the Rhamnaceae plant, is the brother of Fructus Jujubae family.Medicinal part is the fruits and seeds that has the meat fruit stem, and the fruit stem stalk is concave shape, and meat expands, bronzing when ripe, and smooth no hair, fragrant and sweet good to eat.Spherical fruit includes three bronzing seeds." Chinese dendrology " claims that again it is chicken feet pears, sweet midnight.This plant is born in limes marginis, roadside or the mountain valley, and main product is in Shaanxi Qin crust mountain area, and also there is distribution on ground such as Sichuan, Hubei, Zhejiang, Jiangsu, Anhui, Fujian.It is one of name fruit, also is a kind of rare medical, edible fruit.Li Shizhen (1518-1593 A.D.) claims that it is golden fruit tree, and record in Compendium of Material Medica hentriaconta-volume, and " its son also curls; so with four zhang of wooden Senior Three of it ", " Semen Hoveniae (Fructus Hoveniae) of name, Ye Yuanda such as Mulberry girder; bloom summer; the end of the branch is solid are as chicken feet shape for Semen Hoveniae (Fructus Hoveniae) ... make the trifoliate orange Chinese holly again; flexing meanings of not stretching all, tree racemosus and song ... the sweet in the mouth of chewing is as honey ", and can " the relieving restlessness warm on diaphragm of quenching the thirst, moistening five ZANG-organs, diuresis, the same Mel of function ".The successive dynasties physician also often is used in it in the side of relieving the effect of alcohol as principal agent, and curative effect is fine.
Claim in motherland's medical science monograph that Semen Hoveniae (Fructus Hoveniae) is flat, sweet in the mouth is sour, goes into spleen, lung two warps, cure mainly drunk, dysphoria with smothery sensation, thirsty, vomiting, difficulty in urination and defecation.Having the human rabbit to make pharmacological evaluation, find that this medicine has significant diuresis, is a kind of good medicine that relieves the effect of alcohol.Modern medicine study shows that Semen Hoveniae (Fructus Hoveniae) contains glucose, fructose, potassium nitrate, peroxidase etc.Semen Hoveniae (Fructus Hoveniae) and compound recipe thereof can significantly reduce the concentration of ethanol in blood, promote alcoholic acid removing, eliminate the interior excessive free radicals that produces of body after drinking, hinder the formation of lipid peroxide, thereby alleviate the damage of ethanol, avoid alcoholism to cause various Developmental and Metabolic Disorder, bring out various diseases hepatic tissue.In addition, Semen Hoveniae (Fructus Hoveniae) still digests human body and crosses blubbery health fruit, and often eating can defatting beauty.
Three, Flos puerariae lobatae: all claim it in Shennong's Herbal, " medicine is complete works of ", " the difficult sick piece of writing of east doctor's treasured book ", Compendium of Material Medica etc.: " relieving acute alcoholism and recuperating the spleen ", so among the people, even in the traditional Chinese medical science field of China, have over the past thousands of years: the saying of " thousand glasss of not liquor-saturated kudzu ".Simultaneously Flos puerariae lobatae is infused into tea, drink not only have an antialcoholism function, have heat-clearing and toxic substances removing, nourishing the liver simultaneously, protect stomach, the effect of the kidney invigorating.Brainstrust has been opened the fan that Flos Pueraria omeiensis relieves the effect of alcohol by a large amount of scientific experimentss and clinical trial for us: contain abundant saponin and isoflavone in the Flos Pueraria omeiensis, it can effectively suppress the absorption of the intestines and stomach to ethanol, promote the decomposition and the drainage of ethanol in the blood, reach relieve the effect of alcohol, the effect of hepatoprotective, nourishing the stomach, the kidney invigorating, and without any side effects, also therefore be described as " jinx of wine ".Drank in preceding 15 minutes at wine capacity for liquor is heightened, drink after drinking and then can impel ethanol to decompose fast and drain, thereby sober up rapidly, alleviate liver pressure.
Five, the Radix Astragali: the Radix Astragali is the Chinese medicine resistance and supplementing qi medicine.Now having confirmed has facilitation to body's immunological function.Experiment shows that the Radix Astragali can strengthen the phagocytic function of reticuloendothelial system significantly, and its action intensity and bacillus calmette-guerin vaccine are close, the Radix Astragali with share with Radix Codonopsis, its effect that strengthens the reticuloendothelial system phagocytic function is particularly remarkable, is strong than bacillus calmette-guerin vaccine.Have cellular immune function potentiation again, can promote the function that healthy human lymphocyte transforms, most of hepatitis B patients SK-SD skin test when obtaining curative effect changes sun and strengthens.Take the Radix Astragali and can obviously improve the function of human leukocytes inducement interferon, and see that the content of IgA and IgG rises in the easy catching a cold patient nose secretion.The Radix Astragali and extract thereof can make mice plasma ring phosphorus gland former times (cAMP) level improve, and this may be relevant with the content of its raising interferon.Visible leukocyte of animal experiment and multinuclear leucocyte increase significantly.
Clinical research shows, Radix Astragali injection can be used for various types of hepatitis patients, especially be applicable to the chronic persistent hepatitis (CPH) of cellular immune function reduction and the patient of chronic active hepatitis (CAH), but appetite stimulator, improve liver function, strengthen cellular immunization, reduce hbs antigen (HB-sAg) titre or make it to turn out cloudy.The chronic tracheitis patient who is used for typical insufficiency of the spleen symptom, insufficiency of the spleen doing well,improving in the most patients 20 days.Experimentation shows that the Radix Astragali infects mice I type parainfluenza virus slight protective effect, and testing the conclusive evidence Radix Astragali through the crowd has the anti-effect that cures cold.With Radix Codonopsis pairing nephritic proteinuria therapeutical effect is arranged.
The effect of Radix Et Caulis Acanthopanacis Senticosi: the effect of replenishing QI to invigorate the spleen, tonifying the kidney for tranquilization cures mainly that soreness of the waist and knees, body void are weak, insomnia and dreamful sleep, promotion human immunity.
The Rhizoma Alpiniae Officinarum volatile oil content is 0.3~0.5% (Yunnan and Guangxi medicine inspecting institute data).Contain methyl cinnamate 48%, eucalyptol 20~30%, Camphora etc. in the volatile oil.The Rhizoma Alpiniae Officinarum ligroin extraction has phlegm-dispelling functions preferably, and the bronchus secretion is increased, and the volatility part can directly stimulate broncheal gland, but not volatile fraction then passes through the reflection generation effect of gastric mucosa.
Vitamin B1 in the vitamin B group claims thiamine again, and B2 claims riboflavin again, and B3 claims pantothenic acid again, and B5 claims nicotinic acid again, and B11 claims folic acid again.The content of vitamin B group is as shown in table 3 in the Folium Camelliae sinensis.Vitamin B group comprises B1, B2, B6 and B12, also has folic acid, pantothenic acid, nicotinic acid etc., their can releive emotion, Cure for insomnia, asthma, hepatitis, keep the metabolism of human body, but because the modern diet structure becomes more meticulous, not enough to the vitamin B group picked-up at ordinary times, therefore by vitamin B group additional being played the effect of protecting, improving liver function that protects the liver.

Claims (2)

1, a kind of the liver protecting is removed alcohol intoxication antifatigue nutritional health food, and it is characterized in that: the weight proportion of its component is a Radix Puerariae: 300-350 gram, Flos puerariae lobatae 300-350 gram, Semen Hoveniae (Fructus Hoveniae) 800-900 gram, Flos Chrysanthemi 400-500 gram, Semen Lablab Album 200-300 gram, Rhizoma Alpiniae Officinarum 100-150 gram, Radix Et Caulis Acanthopanacis Senticosi 100-150 gram, Radix Astragali 100-150 gram, vitamin B complex 200-250 gram.
2, a kind of the liver protecting is removed the preparation technology of alcohol intoxication antifatigue nutritional health food, it is characterized in that: (1) will clean the Radix Puerariae of after drying, Flos puerariae lobatae, Semen Hoveniae (Fructus Hoveniae), Flos Chrysanthemi, Semen Lablab Album, Rhizoma Alpiniae Officinarum, Radix Et Caulis Acanthopanacis Senticosi, the Radix Astragali, be mixed into mechanical activation comminution, granularity is controlled at about 20 orders, mixed powder is put into basin, carry out enzymolysis processing, the water that adds 10 times of raw material weights earlier, adjust pH value scope 4.5----5.0, heat to 50----55 degree centigrade, add pectase 1.1%, proteinase-10 .7% starts agitator and is mixed, enzymolysis kept 4 hours, the middle stirring 1 time; (2) water is carried: raw material slag and enzymolysis solution directly are warmed up to 85----90 degree centigrade, kept 2.0----2.5 hour, coarse filtration: after raw material slag and extracting solution be cooled to room temperature, carry out screen cloth coarse filtration and filter cloth earlier and filter, the filtering residue list is put and is prepared enzymolysis and water extraction for the second time, for the first time filtrate to put into basin stand-by, same operation is advanced three times, both do the second time, extracted for the third time, again three lixiviating solution had been lumped together, carried out next procedure; (3) fine straining: with kieselguhr cardboard filter machine, above-mentioned three kinds of mixed extracts are carried out fine straining, getting filtrate, to put into basin stand-by, (4) vacuum and low temperature concentrates: use vacuum concentration pot, above-mentioned filtrate is concentrated, liquid relative density 1.15-1.18 (5) drying after concentrating: medicinal liquid is carried out spray drying, and inlet temperature is controlled at about 160 ℃, and leaving air temp is controlled at about 70 ℃; (6) mix: spray drying medicated powder is mixed with compound vitamin, adopt powerful V-Mixer mixing 15-20 minute, (7) capsule fill: the above-mentioned medicated powder that is mixed is adorned capsule with capsule filling machine, require capsule loading amount 0.25 gram/grain for qualified.
CNA2006100103978A 2006-08-11 2006-08-11 Nutritious health food for protecting liver and neutralizing the effect of alcohol and its preparation Pending CN1927361A (en)

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Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101401603B (en) * 2008-11-11 2011-07-20 邓丽菊 Tea for relieving or neutralizing the effect of alcohol to protect liver
CN102894436A (en) * 2011-07-25 2013-01-30 江西食方食坊中药食品有限公司 Hovenia dulcis beverage with hangover alleviating effect, and preparation method thereof
CN103656439A (en) * 2012-09-06 2014-03-26 张金荣 Traditional Chinese medicine composition for sobering up and protecting liver and preparation method of oral liquid thereof
CN104126796A (en) * 2014-07-18 2014-11-05 吴自伟 Health care food capable of dispelling effects of alcohol
CN104274705A (en) * 2014-09-23 2015-01-14 苏州市天灵中药饮片有限公司 Sobering and liver protecting chewable tablet and preparation method thereof
CN104939095A (en) * 2015-06-12 2015-09-30 蚌埠市丰牧牛羊肉制品有限责任公司 De-alcoholic capsules
CN106173714A (en) * 2016-07-16 2016-12-07 王金杰 A kind of beverage of liver-protecting and stomach-nourishing and preparation method thereof
CN106616185A (en) * 2017-01-04 2017-05-10 云南农业大学 Processing process of health type coix seed solid beverage
CN107105742A (en) * 2014-10-13 2017-08-29 韩国韩医学研究院 Contain Semen Lablab Album extract as the composition for being used to preventing or improving NASH disease of active ingredient
CN108576814A (en) * 2018-04-28 2018-09-28 成都市宏智达科技有限公司 One kind is relieved the effect of alcohol mixture and preparation method thereof

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101401603B (en) * 2008-11-11 2011-07-20 邓丽菊 Tea for relieving or neutralizing the effect of alcohol to protect liver
CN102894436A (en) * 2011-07-25 2013-01-30 江西食方食坊中药食品有限公司 Hovenia dulcis beverage with hangover alleviating effect, and preparation method thereof
WO2013013497A1 (en) * 2011-07-25 2013-01-31 江西食方食坊中药食品有限公司 Hovenia acerba drink with effect of curing drunkenness and preparation method thereof
CN103656439A (en) * 2012-09-06 2014-03-26 张金荣 Traditional Chinese medicine composition for sobering up and protecting liver and preparation method of oral liquid thereof
CN104126796A (en) * 2014-07-18 2014-11-05 吴自伟 Health care food capable of dispelling effects of alcohol
CN104274705A (en) * 2014-09-23 2015-01-14 苏州市天灵中药饮片有限公司 Sobering and liver protecting chewable tablet and preparation method thereof
CN107105742A (en) * 2014-10-13 2017-08-29 韩国韩医学研究院 Contain Semen Lablab Album extract as the composition for being used to preventing or improving NASH disease of active ingredient
CN104939095A (en) * 2015-06-12 2015-09-30 蚌埠市丰牧牛羊肉制品有限责任公司 De-alcoholic capsules
CN106173714A (en) * 2016-07-16 2016-12-07 王金杰 A kind of beverage of liver-protecting and stomach-nourishing and preparation method thereof
CN106616185A (en) * 2017-01-04 2017-05-10 云南农业大学 Processing process of health type coix seed solid beverage
CN108576814A (en) * 2018-04-28 2018-09-28 成都市宏智达科技有限公司 One kind is relieved the effect of alcohol mixture and preparation method thereof

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