CN1922146A - 四氢喹啉酮及其作为促代谢谷氨酸受体拮抗剂的用途 - Google Patents
四氢喹啉酮及其作为促代谢谷氨酸受体拮抗剂的用途 Download PDFInfo
- Publication number
- CN1922146A CN1922146A CNA2005800060497A CN200580006049A CN1922146A CN 1922146 A CN1922146 A CN 1922146A CN A2005800060497 A CNA2005800060497 A CN A2005800060497A CN 200580006049 A CN200580006049 A CN 200580006049A CN 1922146 A CN1922146 A CN 1922146A
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- Prior art keywords
- quinoline
- dihydro
- ketone
- alkyl
- dimethyl
- Prior art date
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- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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- General Chemical & Material Sciences (AREA)
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- Neurology (AREA)
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- Diabetes (AREA)
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- Obesity (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US54878804P | 2004-02-27 | 2004-02-27 | |
| US60/548,788 | 2004-02-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1922146A true CN1922146A (zh) | 2007-02-28 |
Family
ID=34911013
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2005800060497A Pending CN1922146A (zh) | 2004-02-27 | 2005-02-25 | 四氢喹啉酮及其作为促代谢谷氨酸受体拮抗剂的用途 |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US7598384B2 (enExample) |
| EP (1) | EP1723116B1 (enExample) |
| JP (1) | JP4712027B2 (enExample) |
| KR (1) | KR100846347B1 (enExample) |
| CN (1) | CN1922146A (enExample) |
| AR (1) | AR049006A1 (enExample) |
| AT (1) | ATE409182T1 (enExample) |
| AU (1) | AU2005217199B2 (enExample) |
| BR (1) | BRPI0508225A (enExample) |
| CA (1) | CA2556653C (enExample) |
| DE (1) | DE602005009929D1 (enExample) |
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| KR101450356B1 (ko) | 2006-11-24 | 2014-10-15 | 에이씨 이뮨 에스.에이. | 알츠하이머와 같은 아밀로이드 또는 아밀로이드-유사 단백질과 관련된 질환의 치료를 위한 n-(메틸)-1h-피라졸-3-아민, n-(메틸)-피리딘-2-아민 및 n-(메틸)-티아졸-2-아민 유도체 |
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| WO2010099217A1 (en) | 2009-02-25 | 2010-09-02 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
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| GB0003632D0 (en) | 2000-02-16 | 2000-04-05 | Univ Hong Kong Science & Techn | Dimeric compounds |
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| BR0308945A (pt) * | 2002-03-29 | 2005-01-04 | Janssen Pharmaceutica Nv | Derivados radiomarcados de quinolina e quinolinona e uso dos mesmos como ligantes para receptores de glutamato metabotrópicos |
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2005
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- 2005-02-25 KR KR1020067017249A patent/KR100846347B1/ko not_active Expired - Fee Related
- 2005-02-25 CN CNA2005800060497A patent/CN1922146A/zh active Pending
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- 2005-02-25 DK DK05717798T patent/DK1723116T3/da active
- 2005-02-25 CA CA2556653A patent/CA2556653C/en not_active Expired - Fee Related
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104262243A (zh) * | 2009-10-15 | 2015-01-07 | Ac免疫有限公司 | 用于治疗与淀粉状蛋白有关的疾病或用于治疗眼部疾病的2,6-二氨基吡啶化合物 |
| CN104262243B (zh) * | 2009-10-15 | 2017-04-12 | Ac免疫有限公司 | 用于治疗与淀粉状蛋白有关的疾病或用于治疗眼部疾病的2,6‑二氨基吡啶化合物 |
| CN103298789A (zh) * | 2010-11-16 | 2013-09-11 | 通用电气健康护理有限公司 | 作为τ蛋白病理成像探针的杂环化合物 |
| CN104755471A (zh) * | 2012-08-30 | 2015-07-01 | 日本新药株式会社 | 吡啶衍生物及药物 |
| CN104513200A (zh) * | 2013-09-26 | 2015-04-15 | 江苏苏中药业集团股份有限公司 | 取代丁烯酰胺的马来酸盐及其晶型 |
| CN104513200B (zh) * | 2013-09-26 | 2017-05-03 | 江苏苏中药业集团股份有限公司 | 取代丁烯酰胺的马来酸盐及其晶型 |
Also Published As
| Publication number | Publication date |
|---|---|
| KR100846347B1 (ko) | 2008-07-15 |
| EA010656B1 (ru) | 2008-10-30 |
| IL177524A (en) | 2012-02-29 |
| JP4712027B2 (ja) | 2011-06-29 |
| PL1723116T3 (pl) | 2009-04-30 |
| WO2005082856A2 (en) | 2005-09-09 |
| KR20070001975A (ko) | 2007-01-04 |
| AR049006A1 (es) | 2006-06-21 |
| US20050197361A1 (en) | 2005-09-08 |
| DE602005009929D1 (de) | 2008-11-06 |
| ATE409182T1 (de) | 2008-10-15 |
| AU2005217199A1 (en) | 2005-09-09 |
| EP1723116A2 (en) | 2006-11-22 |
| EA200601556A1 (ru) | 2007-02-27 |
| UY28775A1 (es) | 2005-04-29 |
| BRPI0508225A (pt) | 2007-07-17 |
| SI1723116T1 (sl) | 2009-04-30 |
| TW200534857A (en) | 2005-11-01 |
| JP2007524710A (ja) | 2007-08-30 |
| EP1723116B1 (en) | 2008-09-24 |
| TWI301760B (en) | 2008-10-11 |
| CA2556653A1 (en) | 2005-09-09 |
| WO2005082856A3 (en) | 2005-11-24 |
| IL177524A0 (en) | 2006-12-10 |
| UA83549C2 (uk) | 2008-07-25 |
| ZA200606686B (en) | 2008-01-30 |
| CA2556653C (en) | 2011-08-16 |
| PT1723116E (pt) | 2009-01-02 |
| AU2005217199B2 (en) | 2008-06-26 |
| ES2315853T3 (es) | 2009-04-01 |
| US7598384B2 (en) | 2009-10-06 |
| DK1723116T3 (da) | 2009-02-02 |
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