CN1905857A - 液体剂型的托吡酯的受控释放 - Google Patents

液体剂型的托吡酯的受控释放 Download PDF

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Publication number
CN1905857A
CN1905857A CNA200480039213XA CN200480039213A CN1905857A CN 1905857 A CN1905857 A CN 1905857A CN A200480039213X A CNA200480039213X A CN A200480039213XA CN 200480039213 A CN200480039213 A CN 200480039213A CN 1905857 A CN1905857 A CN 1905857A
Authority
CN
China
Prior art keywords
dosage form
topiramate
layer
liquid
hydrophilic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA200480039213XA
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English (en)
Chinese (zh)
Inventor
李少玲
林仲强
董良昶
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alza Corp
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Publication of CN1905857A publication Critical patent/CN1905857A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

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  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CNA200480039213XA 2003-11-14 2004-11-12 液体剂型的托吡酯的受控释放 Pending CN1905857A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51995803P 2003-11-14 2003-11-14
US60/519,958 2003-11-14

Publications (1)

Publication Number Publication Date
CN1905857A true CN1905857A (zh) 2007-01-31

Family

ID=34619401

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA200480039213XA Pending CN1905857A (zh) 2003-11-14 2004-11-12 液体剂型的托吡酯的受控释放

Country Status (13)

Country Link
US (1) US20050129765A1 (cg-RX-API-DMAC7.html)
EP (1) EP1684713A1 (cg-RX-API-DMAC7.html)
JP (1) JP2007511519A (cg-RX-API-DMAC7.html)
KR (1) KR20060120193A (cg-RX-API-DMAC7.html)
CN (1) CN1905857A (cg-RX-API-DMAC7.html)
AU (1) AU2004291081A1 (cg-RX-API-DMAC7.html)
CA (1) CA2545834A1 (cg-RX-API-DMAC7.html)
IL (1) IL175605A0 (cg-RX-API-DMAC7.html)
MX (1) MXPA06005462A (cg-RX-API-DMAC7.html)
NO (1) NO20062739L (cg-RX-API-DMAC7.html)
TW (1) TW200528144A (cg-RX-API-DMAC7.html)
WO (1) WO2005048981A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA200604882B (cg-RX-API-DMAC7.html)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102579367A (zh) * 2012-03-23 2012-07-18 中国人民解放军军事医学科学院毒物药物研究所 托吡酯缓释药物组合物、其制备方法及用途
US9421188B2 (en) 2012-03-23 2016-08-23 Institute Of Pharmacology And Toxicology Academy Of Military Medical Sciences P.L.A. China Combination product comprising phentermine and topiramate, and preparation method thereof
US9457008B2 (en) 2012-03-23 2016-10-04 Institute Of Pharmacology And Toxicology Academy Of Military Medical Sciences P.L.A. China Joint product comprising synephrine and topiramate
CN108379588A (zh) * 2018-03-05 2018-08-10 合肥合源药业有限公司 托吡酯组合物

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MXPA06002067A (es) * 2003-08-22 2006-08-11 Johnson & Johnson Suministro gradual de topiramato durante periodo prolongado.
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AU2004312082A1 (en) * 2003-12-29 2005-07-21 Alza Corporation, Inc. Novel drug compositions and dosage forms
MX2007014713A (es) * 2005-05-25 2008-02-14 Janssen Pharmaceutica Nv Formulacion pediatrica de topiramato.
WO2008027557A2 (en) * 2006-08-31 2008-03-06 Spherics, Inc. Topiramate compositions and methods of enhancing its bioavailability
EP2394643B1 (en) 2006-11-17 2015-09-02 Supernus Pharmaceuticals, Inc. Sustained-release formulations of topiramate
EP2363113B1 (en) * 2006-12-04 2017-08-02 Supernus Pharmaceuticals, Inc. Enhanced immediate release formulations of topiramate
EP2219624A2 (en) * 2007-11-08 2010-08-25 Glaxo Group Limited Pharmaceutical formulations
US20120145572A1 (en) * 2009-04-20 2012-06-14 Ecole Polytechnique Federale De Lausanne (Epfl) Containers assembled in fluid and corresponding production
US8652527B1 (en) 2013-03-13 2014-02-18 Upsher-Smith Laboratories, Inc Extended-release topiramate capsules
US9101545B2 (en) 2013-03-15 2015-08-11 Upsher-Smith Laboratories, Inc. Extended-release topiramate capsules
US20210169844A1 (en) 2019-12-10 2021-06-10 Tulex Pharmaceuticals Inc. Compositions and methods for treating epilepsy, seizures and other conditions
US12290504B2 (en) 2023-04-11 2025-05-06 Tap Pharmaceuticals Ag Aqueous formulations of topiramate

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102579367A (zh) * 2012-03-23 2012-07-18 中国人民解放军军事医学科学院毒物药物研究所 托吡酯缓释药物组合物、其制备方法及用途
US9421188B2 (en) 2012-03-23 2016-08-23 Institute Of Pharmacology And Toxicology Academy Of Military Medical Sciences P.L.A. China Combination product comprising phentermine and topiramate, and preparation method thereof
US9457008B2 (en) 2012-03-23 2016-10-04 Institute Of Pharmacology And Toxicology Academy Of Military Medical Sciences P.L.A. China Joint product comprising synephrine and topiramate
CN108379588A (zh) * 2018-03-05 2018-08-10 合肥合源药业有限公司 托吡酯组合物

Also Published As

Publication number Publication date
JP2007511519A (ja) 2007-05-10
IL175605A0 (en) 2006-09-05
US20050129765A1 (en) 2005-06-16
TW200528144A (en) 2005-09-01
ZA200604882B (en) 2007-11-28
AU2004291081A1 (en) 2005-06-02
WO2005048981A1 (en) 2005-06-02
CA2545834A1 (en) 2005-06-02
NO20062739L (no) 2006-08-14
MXPA06005462A (es) 2006-12-15
EP1684713A1 (en) 2006-08-02
KR20060120193A (ko) 2006-11-24

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C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication