CA2545834A1 - Controlled release of topiramate in liquid dosage forms - Google Patents
Controlled release of topiramate in liquid dosage forms Download PDFInfo
- Publication number
- CA2545834A1 CA2545834A1 CA002545834A CA2545834A CA2545834A1 CA 2545834 A1 CA2545834 A1 CA 2545834A1 CA 002545834 A CA002545834 A CA 002545834A CA 2545834 A CA2545834 A CA 2545834A CA 2545834 A1 CA2545834 A1 CA 2545834A1
- Authority
- CA
- Canada
- Prior art keywords
- dosage form
- topiramate
- layer
- drug
- liquid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Classifications
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
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| US51995803P | 2003-11-14 | 2003-11-14 | |
| US60/519,958 | 2003-11-14 | ||
| PCT/US2004/037616 WO2005048981A1 (en) | 2003-11-14 | 2004-11-12 | Controlled release of topirimate in liquid dosage forms |
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| CA2545834A1 true CA2545834A1 (en) | 2005-06-02 |
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| CA002545834A Abandoned CA2545834A1 (en) | 2003-11-14 | 2004-11-12 | Controlled release of topiramate in liquid dosage forms |
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| US20050232995A1 (en) | 2002-07-29 | 2005-10-20 | Yam Nyomi V | Methods and dosage forms for controlled delivery of paliperidone and risperidone |
| MXPA06002067A (es) * | 2003-08-22 | 2006-08-11 | Johnson & Johnson | Suministro gradual de topiramato durante periodo prolongado. |
| WO2005065648A2 (en) * | 2003-12-29 | 2005-07-21 | Alza Corporation, Inc., | Novel drug compositions and dosage forms of topiramate |
| AU2004312082A1 (en) * | 2003-12-29 | 2005-07-21 | Alza Corporation, Inc. | Novel drug compositions and dosage forms |
| MX2007014713A (es) * | 2005-05-25 | 2008-02-14 | Janssen Pharmaceutica Nv | Formulacion pediatrica de topiramato. |
| WO2008027557A2 (en) * | 2006-08-31 | 2008-03-06 | Spherics, Inc. | Topiramate compositions and methods of enhancing its bioavailability |
| EP2394643B1 (en) | 2006-11-17 | 2015-09-02 | Supernus Pharmaceuticals, Inc. | Sustained-release formulations of topiramate |
| EP2363113B1 (en) * | 2006-12-04 | 2017-08-02 | Supernus Pharmaceuticals, Inc. | Enhanced immediate release formulations of topiramate |
| EP2219624A2 (en) * | 2007-11-08 | 2010-08-25 | Glaxo Group Limited | Pharmaceutical formulations |
| US20120145572A1 (en) * | 2009-04-20 | 2012-06-14 | Ecole Polytechnique Federale De Lausanne (Epfl) | Containers assembled in fluid and corresponding production |
| CN102579367B (zh) * | 2012-03-23 | 2014-03-12 | 中国人民解放军军事医学科学院毒物药物研究所 | 托吡酯缓释药物组合物、其制备方法及用途 |
| CN103316026B (zh) | 2012-03-23 | 2016-05-11 | 中国人民解放军军事医学科学院毒物药物研究所 | 含芬特明和托吡酯的联合产品及其制备方法 |
| EP2829270B1 (en) | 2012-03-23 | 2020-11-11 | Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China | Joint product containing synephrine and topiramate |
| US8652527B1 (en) | 2013-03-13 | 2014-02-18 | Upsher-Smith Laboratories, Inc | Extended-release topiramate capsules |
| US9101545B2 (en) | 2013-03-15 | 2015-08-11 | Upsher-Smith Laboratories, Inc. | Extended-release topiramate capsules |
| CN108379588B (zh) * | 2018-03-05 | 2024-07-02 | 合肥合源药业有限公司 | 托吡酯组合物 |
| US20210169844A1 (en) | 2019-12-10 | 2021-06-10 | Tulex Pharmaceuticals Inc. | Compositions and methods for treating epilepsy, seizures and other conditions |
| US12290504B2 (en) | 2023-04-11 | 2025-05-06 | Tap Pharmaceuticals Ag | Aqueous formulations of topiramate |
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| US3865108A (en) * | 1971-05-17 | 1975-02-11 | Ortho Pharma Corp | Expandable drug delivery device |
| US3845770A (en) * | 1972-06-05 | 1974-11-05 | Alza Corp | Osmatic dispensing device for releasing beneficial agent |
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| US4002173A (en) * | 1974-07-23 | 1977-01-11 | International Paper Company | Diester crosslinked polyglucan hydrogels and reticulated sponges thereof |
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| US4513006A (en) * | 1983-09-26 | 1985-04-23 | Mcneil Lab., Inc. | Anticonvulsant sulfamate derivatives |
| US4627850A (en) * | 1983-11-02 | 1986-12-09 | Alza Corporation | Osmotic capsule |
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| US4915949A (en) * | 1987-07-13 | 1990-04-10 | Alza Corporation | Dispenser with movable matrix comprising a plurality of tiny pills |
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| US4931285A (en) * | 1988-04-28 | 1990-06-05 | Alza Corporation | Aqueous based pharmaceutical coating composition for dosage forms |
| US5006346A (en) * | 1988-04-28 | 1991-04-09 | Alza Corporation | Delivery system |
| CA1340821C (en) * | 1988-10-06 | 1999-11-16 | Nobuyuki Fukazawa | Heterocyclic compounds and anticancer-drug reinforcing agents containing them as effective components |
| US5126142A (en) * | 1989-07-18 | 1992-06-30 | Alza Corporation | Dispenser comprising ionophore |
| US5324280A (en) * | 1990-04-02 | 1994-06-28 | Alza Corporation | Osmotic dosage system for delivering a formulation comprising liquid carrier and drug |
| US5190765A (en) * | 1991-06-27 | 1993-03-02 | Alza Corporation | Therapy delayed |
| US5252338A (en) * | 1991-06-27 | 1993-10-12 | Alza Corporation | Therapy delayed |
| AU651244B2 (en) * | 1991-09-19 | 1994-07-14 | Mcneilab, Inc. | Process for the preparation of chlorosulfate and sulfamate derivatives of 2,3:4,5-bis-0-(1-methylethylidene)-beta-D- fructopyranose and (1-methylcyclohexyl)methanol |
| US5643909A (en) * | 1993-04-19 | 1997-07-01 | Syntex (U.S.A.) Inc. | 10,11-Methanodibenzosuberane derivatives |
| ZA953078B (en) * | 1994-04-28 | 1996-01-05 | Alza Corp | Effective therapy for epilepsies |
| US5633011A (en) * | 1994-08-04 | 1997-05-27 | Alza Corporation | Progesterone replacement therapy |
| US5614578A (en) * | 1994-10-28 | 1997-03-25 | Alza Corporation | Injection-molded dosage form |
| US5824638A (en) * | 1995-05-22 | 1998-10-20 | Shire Laboratories, Inc. | Oral insulin delivery |
| US6551613B1 (en) * | 1998-09-08 | 2003-04-22 | Alza Corporation | Dosage form comprising therapeutic formulation |
| US6174547B1 (en) * | 1999-07-14 | 2001-01-16 | Alza Corporation | Dosage form comprising liquid formulation |
| DE69915346T2 (de) * | 1998-12-17 | 2004-07-22 | Alza Corp., Mountain View | Umwandlung von flüssigkeitsgefüllten gelatinkapseln in systeme mit gesteuerter wirkstoffabgabe durch mehrfache beschichtungen |
| US6342249B1 (en) * | 1998-12-23 | 2002-01-29 | Alza Corporation | Controlled release liquid active agent formulation dosage forms |
| US6559293B1 (en) * | 2002-02-15 | 2003-05-06 | Transform Pharmaceuticals, Inc. | Topiramate sodium trihydrate |
| DE60322371D1 (de) * | 2002-03-29 | 2008-09-04 | Alza Corp | Volumensparende arzneiform zur kontrollierten freisetzung |
| US20070243254A1 (en) * | 2002-06-26 | 2007-10-18 | David Edgren | Novel drug compositions and dosage forms of topiramate |
| EP1534238A1 (en) * | 2002-07-29 | 2005-06-01 | ALZA Corporation | Formulations and dosage forms for controlled delivery of topiramate |
-
2004
- 2004-11-12 EP EP04819096A patent/EP1684713A1/en not_active Withdrawn
- 2004-11-12 TW TW093134553A patent/TW200528144A/zh unknown
- 2004-11-12 WO PCT/US2004/037616 patent/WO2005048981A1/en not_active Ceased
- 2004-11-12 CA CA002545834A patent/CA2545834A1/en not_active Abandoned
- 2004-11-12 MX MXPA06005462A patent/MXPA06005462A/es unknown
- 2004-11-12 JP JP2006539847A patent/JP2007511519A/ja active Pending
- 2004-11-12 CN CNA200480039213XA patent/CN1905857A/zh active Pending
- 2004-11-12 KR KR1020067011334A patent/KR20060120193A/ko not_active Withdrawn
- 2004-11-12 US US10/986,962 patent/US20050129765A1/en not_active Abandoned
- 2004-11-12 AU AU2004291081A patent/AU2004291081A1/en not_active Abandoned
-
2006
- 2006-05-11 IL IL175605A patent/IL175605A0/en unknown
- 2006-06-13 ZA ZA200604882A patent/ZA200604882B/en unknown
- 2006-06-13 NO NO20062739A patent/NO20062739L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| JP2007511519A (ja) | 2007-05-10 |
| IL175605A0 (en) | 2006-09-05 |
| US20050129765A1 (en) | 2005-06-16 |
| TW200528144A (en) | 2005-09-01 |
| ZA200604882B (en) | 2007-11-28 |
| AU2004291081A1 (en) | 2005-06-02 |
| CN1905857A (zh) | 2007-01-31 |
| WO2005048981A1 (en) | 2005-06-02 |
| NO20062739L (no) | 2006-08-14 |
| MXPA06005462A (es) | 2006-12-15 |
| EP1684713A1 (en) | 2006-08-02 |
| KR20060120193A (ko) | 2006-11-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |