CN1893919B - 局部施用的杀体内寄生虫组合物 - Google Patents

局部施用的杀体内寄生虫组合物 Download PDF

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Publication number
CN1893919B
CN1893919B CN2004800371839A CN200480037183A CN1893919B CN 1893919 B CN1893919 B CN 1893919B CN 2004800371839 A CN2004800371839 A CN 2004800371839A CN 200480037183 A CN200480037183 A CN 200480037183A CN 1893919 B CN1893919 B CN 1893919B
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CN
China
Prior art keywords
sub
compositions
alkyl
methyl
lactyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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CN2004800371839A
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English (en)
Chinese (zh)
Other versions
CN1893919A (zh
Inventor
V·-R·卡尼坎蒂
T·巴赫
G·阿尔特罗伊特
M·特劳贝尔
H·-J·哈曼
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Intellectual Property GmbH
Original Assignee
Bayer Healthcare AG
Bayer Animal Health GmbH
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Application filed by Bayer Healthcare AG, Bayer Animal Health GmbH filed Critical Bayer Healthcare AG
Publication of CN1893919A publication Critical patent/CN1893919A/zh
Application granted granted Critical
Publication of CN1893919B publication Critical patent/CN1893919B/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A61K9/0017—Non-human animal skin, e.g. pour-on, spot-on
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/15—Depsipeptides; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN2004800371839A 2003-12-13 2004-11-30 局部施用的杀体内寄生虫组合物 Expired - Fee Related CN1893919B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10358525.7 2003-12-13
DE10358525A DE10358525A1 (de) 2003-12-13 2003-12-13 Endoparasitizide Mittel zur topischen Applikation
PCT/EP2004/013552 WO2005055973A2 (de) 2003-12-13 2004-11-30 Endoparasitizide mittel zur topischen applikation

Publications (2)

Publication Number Publication Date
CN1893919A CN1893919A (zh) 2007-01-10
CN1893919B true CN1893919B (zh) 2010-09-29

Family

ID=34638681

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2004800371839A Expired - Fee Related CN1893919B (zh) 2003-12-13 2004-11-30 局部施用的杀体内寄生虫组合物

Country Status (31)

Country Link
US (1) US7763583B2 (https=)
EP (1) EP1694291B1 (https=)
JP (1) JP4842141B2 (https=)
KR (1) KR101272139B1 (https=)
CN (1) CN1893919B (https=)
AR (1) AR046878A1 (https=)
AT (1) ATE447940T1 (https=)
AU (1) AU2004296537B2 (https=)
BR (1) BRPI0417578B1 (https=)
CA (1) CA2548897C (https=)
CR (1) CR8428A (https=)
DE (2) DE10358525A1 (https=)
DK (1) DK1694291T3 (https=)
ES (1) ES2334920T3 (https=)
GT (1) GT200400264A (https=)
HR (1) HRP20100056T1 (https=)
IL (1) IL176151A (https=)
MX (1) MXPA06006594A (https=)
MY (1) MY142044A (https=)
NO (1) NO20063171L (https=)
NZ (1) NZ547837A (https=)
PE (1) PE20050919A1 (https=)
PL (1) PL1694291T3 (https=)
PT (1) PT1694291E (https=)
RU (1) RU2401108C2 (https=)
SI (1) SI1694291T1 (https=)
TW (1) TWI341202B (https=)
UA (1) UA85574C2 (https=)
UY (1) UY28662A1 (https=)
WO (1) WO2005055973A2 (https=)
ZA (1) ZA200604744B (https=)

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US20070148228A1 (en) * 1999-02-22 2007-06-28 Merrion Research I Limited Solid oral dosage form containing an enhancer
DE102004055316A1 (de) * 2004-11-16 2006-05-18 Bayer Healthcare Ag Verhinderung vertikaler Endoparasiten-Infektionen
DE102005011779A1 (de) * 2005-03-11 2006-09-14 Bayer Healthcare Ag Endoparasitizide Mittel
KR101191322B1 (ko) 2006-04-07 2012-10-16 메리온 리서치 Ⅲ 리미티드 증진제를 함유하는 고형 경구용 투여 제형
EP2040731A4 (en) * 2006-06-09 2010-05-19 Merrion Res Iii Ltd SOLID DOSAGE FORM FOR ORAL ADMINISTRATION CONTAINING AN ACTIVATOR
PE20081406A1 (es) * 2006-12-20 2008-10-17 Schering Plough Ltd Composiciones farmaceuticas de flunixina
CN107096012A (zh) * 2008-05-07 2017-08-29 诺和诺德股份有限公司 肽的组合物及其制备方法
DE102008022520A1 (de) * 2008-05-07 2009-11-12 Bayer Animal Health Gmbh Feste Arzneimittelformulierung mit verzögerter Freisetzung
ES2617672T3 (es) * 2008-10-08 2017-06-19 Zoetis Services Llc Composiciones antihelmínticas de bencimidazol
US20100215743A1 (en) * 2009-02-25 2010-08-26 Leonard Thomas W Composition and drug delivery of bisphosphonates
DE102009012423A1 (de) 2009-03-10 2010-09-16 Bayer Animal Health Gmbh Zubereitung auf Ölbasis
AP2909A (en) 2009-03-17 2014-05-31 Concert Pharmaceuticals Inc Pyrazinoisoquinoline Compounds
GB2472327B (en) 2009-07-31 2013-03-13 Shin Nippon Biomedical Lab Ltd Intranasal granisetron and nasal applicator
US20110182985A1 (en) * 2010-01-28 2011-07-28 Coughlan David C Solid Pharmaceutical Composition with Enhancers and Methods of Preparing thereof
WO2011120033A1 (en) 2010-03-26 2011-09-29 Merrion Research Iii Limited Pharmaceutical compositions of selective factor xa inhibitors for oral administration
EP2661273A4 (en) 2011-01-07 2014-06-04 Merrion Res Iii Ltd IRON PHARMACEUTICAL COMPOSITIONS FOR ORAL ADMINISTRATION
US8680054B2 (en) * 2011-04-20 2014-03-25 Novartis Ag Suspension type topical formulations comprising cyclic depsipeptide
CN102283843A (zh) * 2011-06-29 2011-12-21 梁晓天 一种吡喹酮外用制剂及其制备方法和应用
AU2012357848C1 (en) * 2011-12-21 2018-07-19 Bayer Pharma Aktiengesellschaft Preparations containing amorphous emodepside
WO2014098619A1 (en) * 2012-12-18 2014-06-26 Donaghys Industries Limited Transdermal parasiticidal formulations
WO2015123480A2 (en) * 2014-02-14 2015-08-20 Dsm Ip Assets B.V. Compositions and methods for the prevention and/or treatment of schistosomiasis
US10265384B2 (en) 2015-01-29 2019-04-23 Novo Nordisk A/S Tablets comprising GLP-1 agonist and enteric coating
LT3298027T (lt) 2015-05-20 2021-08-10 Boehringer Ingelheim Animal Health USA Inc. Antihelmintiniai depsipeptido junginiai
RU2715556C2 (ru) 2015-12-28 2020-03-02 Мериал, Инк. Противогельминтные депсипептидные соединения
CA3044038A1 (en) 2016-11-16 2018-05-24 Boehringer Ingelheim Animal Health USA Inc. Anthelmintic depsipeptide compounds
EP3480195A1 (en) 2017-11-07 2019-05-08 Bayer Animal Health GmbH Method for the synthesis of cyclic depsipeptides
PL3676265T3 (pl) 2017-11-07 2025-12-15 Elanco Animal Health Gmbh Sposób syntezy cyklicznych depsypeptydów
CN111346046B (zh) * 2020-03-06 2021-07-09 安徽农业大学 一种含莫西菌素注射用缓释凝胶制剂及制备方法

Citations (3)

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US4988696A (en) * 1986-10-11 1991-01-29 Bayer Aktiengesellschaft Dermal treatment of worm diseases in cats with praziquantel
US6340672B1 (en) * 2000-02-16 2002-01-22 Phoenix Scientific, Inc. Parasiticidal formulation and a method of making this formulation
CN1352559A (zh) * 1999-05-12 2002-06-05 拜尔公司 杀内寄生虫组合物

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DE2362539C2 (de) * 1973-12-17 1986-05-07 Merck Patent Gmbh, 6100 Darmstadt 2-Acyl-4-oxo-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isochinoline, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
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DE4317432A1 (de) 1993-05-26 1994-12-01 Bayer Ag Octacyclodepsipeptide mit endoparasitizider Wirkung
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NZ260018A (en) 1994-03-03 1995-10-26 Bomac Lab Ltd Benzimidazole compositions and anthelmintic compositions
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US5780487A (en) 1995-08-07 1998-07-14 Amer Moh Samir S-2'- 2-(1-methyl-2-piperidyl) ethyl! cinnamanilide
DE19601263A1 (de) 1996-01-16 1997-07-17 Bayer Ag Anthelmintische Paste
DE19628776A1 (de) 1996-07-17 1998-01-22 Bayer Ag Oral applizierbare Granulate von Hexahydropyrazinderivaten
US5837289A (en) * 1996-07-23 1998-11-17 Grasela; John C. Transdermal delivery of medications using a combination of penetration enhancers
DE19941024A1 (de) 1999-08-28 2001-03-01 Hartmut Klocke Wirkstoffpräparat für tierärztliche Applikation und Verfahren zu seiner Herstellung
NZ518376A (en) * 1999-11-18 2004-01-30 Novartis Ag Pesticidal aminoheterocyclamide compounds
DE10008128A1 (de) 2000-02-22 2001-08-23 Bayer Ag Endoparasitizide Mittel
ATE320812T1 (de) 2000-10-10 2006-04-15 Wyeth Corp Anthelmintika
TWI292712B (en) * 2000-12-20 2008-01-21 Novartis Ag Aminoacetonitrile compounds for use in the control of endoparasites
GB0108485D0 (en) 2001-04-04 2001-05-23 Pfizer Ltd Combination therapy
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PT1610613T (pt) * 2003-04-04 2017-03-07 Merial Inc Formulações veterinárias anti-helmínticas tópicas

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US4988696A (en) * 1986-10-11 1991-01-29 Bayer Aktiengesellschaft Dermal treatment of worm diseases in cats with praziquantel
CN1352559A (zh) * 1999-05-12 2002-06-05 拜尔公司 杀内寄生虫组合物
US6340672B1 (en) * 2000-02-16 2002-01-22 Phoenix Scientific, Inc. Parasiticidal formulation and a method of making this formulation

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Also Published As

Publication number Publication date
UY28662A1 (es) 2005-07-29
GT200400264A (es) 2005-08-18
BRPI0417578B1 (pt) 2015-12-22
EP1694291A2 (de) 2006-08-30
CA2548897C (en) 2012-04-10
RU2006124964A (ru) 2008-01-20
EP1694291B1 (de) 2009-11-11
PE20050919A1 (es) 2005-12-16
HK1102915A1 (en) 2007-12-07
AU2004296537A1 (en) 2005-06-23
AR046878A1 (es) 2005-12-28
TW200533384A (en) 2005-10-16
WO2005055973A2 (de) 2005-06-23
NO20063171L (no) 2006-07-07
KR101272139B1 (ko) 2013-06-10
TWI341202B (en) 2011-05-01
IL176151A0 (en) 2006-10-05
ATE447940T1 (de) 2009-11-15
DK1694291T3 (da) 2010-03-15
ES2334920T3 (es) 2010-03-17
IL176151A (en) 2013-12-31
PT1694291E (pt) 2010-01-18
US20070060509A1 (en) 2007-03-15
NZ547837A (en) 2010-02-26
JP2007513903A (ja) 2007-05-31
KR20060103953A (ko) 2006-10-04
JP4842141B2 (ja) 2011-12-21
UA85574C2 (uk) 2009-02-10
WO2005055973A3 (de) 2005-08-11
HRP20100056T1 (hr) 2010-03-31
DE502004010367D1 (de) 2009-12-24
ZA200604744B (en) 2007-09-26
DE10358525A1 (de) 2005-07-07
PL1694291T3 (pl) 2010-04-30
AU2004296537B2 (en) 2010-05-13
SI1694291T1 (sl) 2010-03-31
CN1893919A (zh) 2007-01-10
CR8428A (es) 2006-11-23
MXPA06006594A (es) 2006-08-23
MY142044A (en) 2010-08-30
CA2548897A1 (en) 2005-06-23
BRPI0417578A (pt) 2007-03-20
US7763583B2 (en) 2010-07-27
RU2401108C2 (ru) 2010-10-10

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