CN1832956B - 编码IgE信号肽和/或IL-15的核酸序列与包含IgE信号肽和/或IL-15的组合物及其使用方法 - Google Patents

编码IgE信号肽和/或IL-15的核酸序列与包含IgE信号肽和/或IL-15的组合物及其使用方法 Download PDF

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CN1832956B
CN1832956B CN2004800228915A CN200480022891A CN1832956B CN 1832956 B CN1832956 B CN 1832956B CN 2004800228915 A CN2004800228915 A CN 2004800228915A CN 200480022891 A CN200480022891 A CN 200480022891A CN 1832956 B CN1832956 B CN 1832956B
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nucleic acid
protein
cells
sequence
cell
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CN1832956A (zh
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D·B·维纳
M·库茨勒
A·K·楚
J·杨
J·D·博伊尔
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University of Pennsylvania
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5443—IL-15
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55522—Cytokines; Lymphokines; Interferons
    • A61K2039/55527—Interleukins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

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  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
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  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CN2004800228915A 2003-06-13 2004-06-14 编码IgE信号肽和/或IL-15的核酸序列与包含IgE信号肽和/或IL-15的组合物及其使用方法 Expired - Fee Related CN1832956B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US47820503P 2003-06-13 2003-06-13
US47821003P 2003-06-13 2003-06-13
US60/478,205 2003-06-13
US60/478,210 2003-06-13
PCT/US2004/018962 WO2005000235A2 (en) 2003-06-13 2004-06-14 NUCLEIC ACID SEQUENCES ENCODING AND COMPOSITIONS COMPRISING IgE SIGNAL PEPTIDE AND/OR IL-15 AND METHODS FOR USING THE SAME

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CN1832956A CN1832956A (zh) 2006-09-13
CN1832956B true CN1832956B (zh) 2013-11-20

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US (2) US8173786B2 (enExample)
EP (2) EP1638987B1 (enExample)
JP (2) JP2007516696A (enExample)
KR (2) KR101225473B1 (enExample)
CN (1) CN1832956B (enExample)
AU (2) AU2004251070B2 (enExample)
BR (1) BRPI0411363A (enExample)
CA (1) CA2529145C (enExample)
IL (1) IL172496A (enExample)
MX (1) MXPA05013526A (enExample)
NZ (2) NZ570709A (enExample)
WO (1) WO2005000235A2 (enExample)

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WO2005000235A3 (en) 2005-06-16
US8173786B2 (en) 2012-05-08
EP1638987B1 (en) 2014-11-19
US20070041941A1 (en) 2007-02-22
CN1832956A (zh) 2006-09-13
AU2012202867B2 (en) 2015-01-29
AU2012202867A1 (en) 2012-06-07
EP1638987A2 (en) 2006-03-29
CA2529145A1 (en) 2005-01-06
AU2004251070A1 (en) 2005-01-06
EP1638987A4 (en) 2007-12-26
NZ544077A (en) 2009-01-31
IL172496A0 (en) 2006-04-10
EP2292634A2 (en) 2011-03-09
JP5623444B2 (ja) 2014-11-12
KR20060030041A (ko) 2006-04-07
WO2005000235A2 (en) 2005-01-06
KR20110129945A (ko) 2011-12-02
MXPA05013526A (es) 2006-03-09
AU2004251070B2 (en) 2012-02-23
JP2012110345A (ja) 2012-06-14
KR101225473B1 (ko) 2013-01-24
US20120276142A1 (en) 2012-11-01
BRPI0411363A (pt) 2006-07-25
CA2529145C (en) 2017-07-11
JP2007516696A (ja) 2007-06-28
KR101269548B1 (ko) 2013-06-21
NZ570709A (en) 2010-04-30
IL172496A (en) 2013-02-28
EP2292634A3 (en) 2012-08-08

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