BRPI0411363A - seqüências de ácidos nucléicos codificando e composições compreendendo peptìdeo sinal ige e/ou il-15 e processos para uso das mesmas - Google Patents
seqüências de ácidos nucléicos codificando e composições compreendendo peptìdeo sinal ige e/ou il-15 e processos para uso das mesmasInfo
- Publication number
- BRPI0411363A BRPI0411363A BRPI0411363-2A BRPI0411363A BRPI0411363A BR PI0411363 A BRPI0411363 A BR PI0411363A BR PI0411363 A BRPI0411363 A BR PI0411363A BR PI0411363 A BRPI0411363 A BR PI0411363A
- Authority
- BR
- Brazil
- Prior art keywords
- nucleic acid
- compositions
- fusion proteins
- processes
- ige
- Prior art date
Links
- 150000007523 nucleic acids Chemical group 0.000 title abstract 5
- 239000000203 mixture Substances 0.000 title abstract 4
- 108010076504 Protein Sorting Signals Proteins 0.000 title abstract 3
- 108020001507 fusion proteins Proteins 0.000 abstract 5
- 102000037865 fusion proteins Human genes 0.000 abstract 5
- 102000003812 Interleukin-15 Human genes 0.000 abstract 4
- 108090000172 Interleukin-15 Proteins 0.000 abstract 4
- 108020004707 nucleic acids Proteins 0.000 abstract 3
- 102000039446 nucleic acids Human genes 0.000 abstract 3
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 239000013598 vector Substances 0.000 abstract 2
- 108010029697 CD40 Ligand Proteins 0.000 abstract 1
- 102100032937 CD40 ligand Human genes 0.000 abstract 1
- 108010008038 Synthetic Vaccines Proteins 0.000 abstract 1
- 230000002238 attenuated effect Effects 0.000 abstract 1
- 230000002519 immonomodulatory effect Effects 0.000 abstract 1
- 244000052769 pathogen Species 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 229940124551 recombinant vaccine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5443—IL-15
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
- A61K2039/55527—Interleukins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Epidemiology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US47820503P | 2003-06-13 | 2003-06-13 | |
| US47821003P | 2003-06-13 | 2003-06-13 | |
| PCT/US2004/018962 WO2005000235A2 (en) | 2003-06-13 | 2004-06-14 | NUCLEIC ACID SEQUENCES ENCODING AND COMPOSITIONS COMPRISING IgE SIGNAL PEPTIDE AND/OR IL-15 AND METHODS FOR USING THE SAME |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0411363A true BRPI0411363A (pt) | 2006-07-25 |
Family
ID=33555491
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0411363-2A BRPI0411363A (pt) | 2003-06-13 | 2004-06-14 | seqüências de ácidos nucléicos codificando e composições compreendendo peptìdeo sinal ige e/ou il-15 e processos para uso das mesmas |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US8173786B2 (enExample) |
| EP (2) | EP2292634A3 (enExample) |
| JP (2) | JP2007516696A (enExample) |
| KR (2) | KR101225473B1 (enExample) |
| CN (1) | CN1832956B (enExample) |
| AU (2) | AU2004251070B2 (enExample) |
| BR (1) | BRPI0411363A (enExample) |
| CA (1) | CA2529145C (enExample) |
| IL (1) | IL172496A (enExample) |
| MX (1) | MXPA05013526A (enExample) |
| NZ (2) | NZ570709A (enExample) |
| WO (1) | WO2005000235A2 (enExample) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ570709A (en) * | 2003-06-13 | 2010-04-30 | Univ Pennsylvania | Nucleic acid sequences encoding and compositions comprising IgE signal peptide and/or IL-15 and methods for using the same |
| US8178660B2 (en) | 2006-01-13 | 2012-05-15 | The Trustees Of The University Of Pennsylvania | Vaccines and immunotherapeutics using codon optimized IL-15 and methods for using the same |
| CA3184778A1 (en) * | 2006-07-28 | 2008-01-31 | The Trustees Of The University Of Pennsylvania | Hiv consensus envelope sequences and methods for using same |
| US10426827B1 (en) * | 2006-11-06 | 2019-10-01 | Microvax, Llc | Dengue hemorrhagic fever virus vaccine |
| CN101909635B (zh) * | 2008-01-11 | 2014-09-17 | Vgx药品有限责任公司 | 针对多种登革病毒亚型的新颖疫苗 |
| WO2009124309A2 (en) | 2008-04-04 | 2009-10-08 | The Trustees Of The University Of Pennsylvania | Vaccines and immunotherapeutics using il-28 and compositions and methods of using the same |
| ES2588738T3 (es) * | 2008-04-04 | 2016-11-04 | The Trustees Of The University Of Pennsylvania | Secuencias de consenso de proteínas del virus Chikungunya, moléculas de ácido nucleico que las codifican, y composiciones y métodos de uso de las mismas |
| CN102821790A (zh) | 2009-09-14 | 2012-12-12 | 宾夕法尼亚大学托管会 | 包含IL-15受体α和/或编码IL-15受体α的核酸分子的疫苗和免疫治疗剂,以及其使用方法 |
| AU2011213559B2 (en) | 2010-02-08 | 2015-05-07 | The Trustees Of The University Of Pennsylvania | Nucleic acid molecules encoding RANTES, and compositions comprising and methods of using the same |
| US9238679B2 (en) | 2011-02-11 | 2016-01-19 | The Trustees Of The University Of Pennslyvania | Nucleic acid molecule encoding hepatitis B virus core protein and surface antigen protein and vaccine comprising the same |
| EA037377B1 (ru) | 2011-02-11 | 2021-03-22 | Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания | Вакцина для индукции иммунного ответа на hbv |
| EP2791362B1 (en) | 2011-12-12 | 2019-07-03 | The Trustees Of The University Of Pennsylvania | Proteins comprising mrsa pbp2a and fragments thereof, nucleic acids encoding the same, and compositions and their use to prevent and treat mrsa infections |
| CA2870182A1 (en) | 2012-04-10 | 2013-10-17 | The Trustees Of The University Of Pennsylvania | Human respiratory syncytial virus consensus antigens, nucleic acid constructs and vaccines made therefrom, and methods of using same |
| CN110051835A (zh) * | 2012-04-12 | 2019-07-26 | 宾夕法尼亚大学理事会 | 丝状病毒共有抗原、由其制备的核酸构建体和疫苗以及其使用方法 |
| EP3974520A1 (en) * | 2013-05-14 | 2022-03-30 | Board of Regents, The University of Texas System | Human application of engineered chimeric antigen receptor (car) t-cells |
| CA3190002A1 (en) | 2014-02-14 | 2015-08-20 | Board Of Regents, The University Of Texas System | Chimeric antigen receptors and methods of making |
| KR20250108761A (ko) * | 2014-10-01 | 2025-07-15 | 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 | 항원 및 어쥬번트로서 인터류킨-21을 갖는 백신 |
| TN2018000154A1 (en) * | 2015-10-22 | 2019-10-04 | Modernatx Inc | Respiratory syncytial virus vaccine |
| EA201892124A1 (ru) | 2016-12-02 | 2019-04-30 | Дэвид Б. Уэйнер | Днк-конструкции антител и способы их применения |
| CU24546B1 (es) * | 2016-12-30 | 2021-09-07 | Ct Ingenieria Genetica Biotecnologia | Composición vacunal que comprende un mutante de la interleucina-15 humana |
| CA3049652A1 (en) | 2017-01-10 | 2018-07-19 | Intrexon Corporation | Modulating expression of polypeptides via new gene switch expression systems |
| JP7551496B2 (ja) | 2017-10-31 | 2024-09-17 | カリヴィル イムノセラピューティクス, インコーポレイテッド | 全身送達のためのプラットフォーム腫瘍溶解性ベクター |
| CN111479585A (zh) | 2017-12-13 | 2020-07-31 | 艾诺奥医药品有限公司 | 靶向boris的癌症疫苗和其用途 |
| AU2018383658B2 (en) | 2017-12-13 | 2022-02-10 | Inovio Pharmaceuticals, Inc. | Cancer vaccines targeting mesothelin and uses thereof |
| KR20230116955A (ko) | 2017-12-13 | 2023-08-04 | 이노비오 파마수티컬즈, 인크. | Muc16을 표적화하는 암 백신 및 이의 용도 |
| MX2022002747A (es) | 2019-09-10 | 2022-04-06 | Obsidian Therapeutics Inc | Proteinas de fusion de ca2-il15 para regulacion ajustable. |
| JP2023510112A (ja) * | 2019-12-19 | 2023-03-13 | ザ ウィスター インスティテュート オブ アナトミー アンド バイオロジー | アフリカ豚熱ウイルスに対するワクチン、およびそれを使用する方法 |
| US12064481B2 (en) * | 2020-11-02 | 2024-08-20 | Drexel University | Compositions and methods employing adenosine deaminase-1 (ADA-1) as an adjuvant |
| PE20231175A1 (es) | 2020-11-19 | 2023-08-01 | Kalivir Immunotherapeutics Inc | Inmunoterapia oncolitica por remodelacion del microambiente tumoral |
| IL316712B2 (en) * | 2021-04-30 | 2025-12-01 | Kalivir Immunotherapeutics Inc | Oncolytic viruses for modified mhc expression |
| US12605349B2 (en) | 2024-09-05 | 2026-04-21 | Orbus Therapeutics, Inc. | Methods of treating grade 3 astrocytoma |
Family Cites Families (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2157994A (en) | 1937-11-08 | 1939-05-09 | Kelsey Hayes Wheel Co | Brake mechanism |
| US5077044A (en) | 1980-05-19 | 1991-12-31 | The Board Of Trustees Of The Leland Stanford Jr. University | Novel non-reverting shigella live vaccines |
| US4722848A (en) | 1982-12-08 | 1988-02-02 | Health Research, Incorporated | Method for immunizing animals with synthetically modified vaccinia virus |
| US5110587A (en) | 1981-12-24 | 1992-05-05 | Health Research, Incorporated | Immunogenic composition comprising synthetically modified vaccinia virus |
| US5338683A (en) | 1981-12-24 | 1994-08-16 | Health Research Incorporated | Vaccinia virus containing DNA sequences encoding herpesvirus glycoproteins |
| US5174993A (en) | 1981-12-24 | 1992-12-29 | Health Research Inc. | Recombinant avipox virus and immunological use thereof |
| US4945050A (en) | 1984-11-13 | 1990-07-31 | Cornell Research Foundation, Inc. | Method for transporting substances into living cells and tissues and apparatus therefor |
| US5036006A (en) | 1984-11-13 | 1991-07-30 | Cornell Research Foundation, Inc. | Method for transporting substances into living cells and tissues and apparatus therefor |
| GB8508845D0 (en) | 1985-04-04 | 1985-05-09 | Hoffmann La Roche | Vaccinia dna |
| US5223424A (en) | 1985-09-06 | 1993-06-29 | Prutech Research And Development | Attenuated herpesviruses and herpesviruses which include foreign DNA encoding an amino acid sequence |
| US5310668A (en) | 1986-06-20 | 1994-05-10 | Merck & Co., Inc. | Varicella-zoster virus as a live recombinant vaccine |
| US5242829A (en) | 1986-09-23 | 1993-09-07 | Therion Biologics Corporation | Recombinant pseudorabies virus |
| IL86583A0 (en) | 1987-06-04 | 1988-11-15 | Molecular Eng Ass | Vaccine containing a derivative of a microbe and method for the production thereof |
| US5387744A (en) | 1987-06-04 | 1995-02-07 | Washington University | Avirulent microbes and uses therefor: Salmonella typhi |
| US5294441A (en) | 1987-06-04 | 1994-03-15 | Washington University | Avirulent microbes and uses therefor: salmonella typhi |
| US5112749A (en) | 1987-10-02 | 1992-05-12 | Praxis Biologics, Inc. | Vaccines for the malaria circumsporozoite protein |
| US5225336A (en) | 1989-03-08 | 1993-07-06 | Health Research Incorporated | Recombinant poxvirus host range selection system |
| AT400955B (de) | 1989-03-08 | 1996-05-28 | Health Research Inc | Rekombinantes pockenvirus-wirtsselektionssystem |
| US5703055A (en) | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
| WO1990011687A1 (en) | 1989-03-31 | 1990-10-18 | Washington University | VACCINES CONTAINING AVIRULENT phoP-TYPE MICROORGANISMS |
| ES2070997T3 (es) | 1989-12-04 | 1995-06-16 | Akzo Nobel Nv | Virus de herpes recombinante de pavos y vacunas vector vivas derivadas de los mismos. |
| US5294548A (en) | 1990-04-02 | 1994-03-15 | American Biogenetic Sciences, Inc | Recombianant Hepatitis a virus |
| US5462734A (en) | 1990-11-02 | 1995-10-31 | Wisconsin Alumni Research Foundation | Bovine herpesvirus vaccine and method of using same |
| US5240703A (en) | 1991-03-01 | 1993-08-31 | Syntro Corporation | Attenuated, genetically-engineered pseudorabies virus s-prv-155 and uses thereof |
| US5593972A (en) | 1993-01-26 | 1997-01-14 | The Wistar Institute | Genetic immunization |
| US5981505A (en) | 1993-01-26 | 1999-11-09 | The Trustees Of The University Of Pennsylvania | Compositions and methods for delivery of genetic material |
| WO1994016737A1 (en) | 1993-01-26 | 1994-08-04 | Weiner David B | Compositions and methods for delivery of genetic material |
| US5739118A (en) | 1994-04-01 | 1998-04-14 | Apollon, Inc. | Compositions and methods for delivery of genetic material |
| NL9401820A (nl) | 1994-11-02 | 1996-06-03 | Meyn Maschf | Inrichting voor het bewerken van aan zijn poten opgehangen gevogelte. |
| US5962428A (en) | 1995-03-30 | 1999-10-05 | Apollon, Inc. | Compositions and methods for delivery of genetic material |
| ES2305024T3 (es) | 1995-08-01 | 2008-11-01 | F. Hoffmann-La Roche Ag | Receptores para interleuquina-12 humana. |
| CN1257976C (zh) * | 1996-10-23 | 2006-05-31 | 宾夕法尼亚州立大学托管会 | 改良疫苗 |
| WO1999016466A2 (en) * | 1997-09-29 | 1999-04-08 | Beth Israel Deaconess Medical Center | Vaccine compositions and methods of enhancing vaccine efficacy |
| JP2001526241A (ja) * | 1997-12-19 | 2001-12-18 | イミュネックス・コーポレーション | Hiv感染に対する感受性を低下させるための方法 |
| CA2320960A1 (en) * | 1998-02-11 | 1999-08-19 | Maxygen, Inc. | Optimization of immunomodulatory properties of genetic vaccines |
| US7560105B1 (en) * | 1999-10-04 | 2009-07-14 | Leids Universitair Medisch Centrum | Dendritic cells activated in the presence of glucocorticoid hormones are capable of suppressing antigen-specific T cell responses |
| ES2288952T3 (es) * | 2000-05-11 | 2008-02-01 | Baylor Research Institute | Composiciones y metodos para producir celulas presentadoras de antigenos. |
| EP1322338A4 (en) | 2000-10-04 | 2005-04-13 | Univ Pennsylvania | COMPOSITIONS AND METHODS OF USING A CAPSID PROTEIN FROM VARIOUS FLAVIVIRUS AND PESTIVIRUS |
| IL160358A0 (en) | 2001-08-23 | 2004-07-25 | Genmab As | Human antibodies specific for interleukin 15 (il-15) |
| AU2003243663A1 (en) * | 2002-06-20 | 2004-01-06 | The Trustees Of The University Of Pennsylvania | Vaccines for suppressing ige-mediated allergic disease and methods for using the same |
| NZ570709A (en) * | 2003-06-13 | 2010-04-30 | Univ Pennsylvania | Nucleic acid sequences encoding and compositions comprising IgE signal peptide and/or IL-15 and methods for using the same |
| KR20140137679A (ko) | 2013-05-23 | 2014-12-03 | 삼성전자주식회사 | 카드 소켓 장치 |
-
2004
- 2004-06-13 NZ NZ570709A patent/NZ570709A/en not_active IP Right Cessation
- 2004-06-14 KR KR1020117023822A patent/KR101225473B1/ko not_active Expired - Fee Related
- 2004-06-14 NZ NZ544077A patent/NZ544077A/en not_active IP Right Cessation
- 2004-06-14 CA CA2529145A patent/CA2529145C/en not_active Expired - Fee Related
- 2004-06-14 EP EP10191165A patent/EP2292634A3/en not_active Withdrawn
- 2004-06-14 EP EP04776577.1A patent/EP1638987B1/en not_active Expired - Lifetime
- 2004-06-14 WO PCT/US2004/018962 patent/WO2005000235A2/en not_active Ceased
- 2004-06-14 US US10/560,650 patent/US8173786B2/en not_active Expired - Fee Related
- 2004-06-14 CN CN2004800228915A patent/CN1832956B/zh not_active Expired - Fee Related
- 2004-06-14 KR KR1020057023994A patent/KR101269548B1/ko not_active Expired - Fee Related
- 2004-06-14 BR BRPI0411363-2A patent/BRPI0411363A/pt not_active Application Discontinuation
- 2004-06-14 AU AU2004251070A patent/AU2004251070B2/en not_active Ceased
- 2004-06-14 MX MXPA05013526A patent/MXPA05013526A/es active IP Right Grant
- 2004-06-14 JP JP2006533791A patent/JP2007516696A/ja active Pending
-
2005
- 2005-12-11 IL IL172496A patent/IL172496A/en active IP Right Grant
-
2012
- 2012-02-14 JP JP2012029973A patent/JP5623444B2/ja not_active Expired - Fee Related
- 2012-05-07 US US13/466,015 patent/US20120276142A1/en not_active Abandoned
- 2012-05-16 AU AU2012202867A patent/AU2012202867B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| IL172496A0 (en) | 2006-04-10 |
| KR101225473B1 (ko) | 2013-01-24 |
| EP1638987B1 (en) | 2014-11-19 |
| US20120276142A1 (en) | 2012-11-01 |
| WO2005000235A2 (en) | 2005-01-06 |
| CN1832956B (zh) | 2013-11-20 |
| AU2004251070A1 (en) | 2005-01-06 |
| MXPA05013526A (es) | 2006-03-09 |
| AU2004251070B2 (en) | 2012-02-23 |
| KR20110129945A (ko) | 2011-12-02 |
| WO2005000235A3 (en) | 2005-06-16 |
| KR101269548B1 (ko) | 2013-06-21 |
| JP2007516696A (ja) | 2007-06-28 |
| US20070041941A1 (en) | 2007-02-22 |
| EP1638987A4 (en) | 2007-12-26 |
| NZ570709A (en) | 2010-04-30 |
| CN1832956A (zh) | 2006-09-13 |
| NZ544077A (en) | 2009-01-31 |
| JP5623444B2 (ja) | 2014-11-12 |
| EP2292634A3 (en) | 2012-08-08 |
| KR20060030041A (ko) | 2006-04-07 |
| CA2529145C (en) | 2017-07-11 |
| CA2529145A1 (en) | 2005-01-06 |
| AU2012202867A1 (en) | 2012-06-07 |
| JP2012110345A (ja) | 2012-06-14 |
| EP2292634A2 (en) | 2011-03-09 |
| US8173786B2 (en) | 2012-05-08 |
| AU2012202867B2 (en) | 2015-01-29 |
| EP1638987A2 (en) | 2006-03-29 |
| IL172496A (en) | 2013-02-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MXPA05013526A (es) | Secuencias de acido nucleico que codifican y composiciones que comprenden el peptido de senal de ige y/o il-15 y metodos para uso de los mismos. | |
| MX2010005783A (es) | Secuencias de aminoacidos dirigidas contra citoquinas heterodimericas y/o sus receptores y polipeptidos que comprenden las mismas. | |
| EP1548032A4 (en) | KDR-PEPTIDES AND VACCINES CONTAINING THEM | |
| WO2006119987A3 (en) | Recombinant n-glycosylated proteins from procaryotic cells | |
| MX2011008094A (es) | Polipeptidos recombinantes extendidos y composiciones que comprenden los mismos. | |
| DE69934967D1 (de) | Verfahren zur verminderung der immunogenität von proteinen | |
| DE50112802D1 (de) | Peptide, deren herstellung und verwendung zur bindung von immunglobulinen | |
| WO2009024327A3 (en) | New proteins for use in human and animal staphylococcus infections | |
| EP2589658A4 (en) | PARTIAL REGION POLYPEPTIDE OF REIC / DKK-3 PROTEIN | |
| JP2014507146A5 (enExample) | ||
| DE602004027362D1 (de) | Zusammensetzungen und verfahren mit dem respiratory syncytial virus untergruppe b stamm 9320 | |
| ATE455792T1 (de) | Neues phosphatbindendes protein, pharmazeutische zusammensetzungen, die dieses enthalten, und verwendung davon | |
| BR112022026248A2 (pt) | Conjugados de citocinas | |
| DK0918865T3 (da) | Immunologisk aktive proteiner af Borrelia burgdorferi, derfor kodende nukleinsyrer samt deres anvendelse i testkits og som vacciner | |
| WO2007029262A3 (en) | Compositions and methods using same for the detection of viruses | |
| NO20081541L (no) | Ny sjo-lus vaksine | |
| DK1664097T3 (da) | Piroplasmidvaccine | |
| DE50106199D1 (de) | Regulatorische sequenz zur spezifischen expression in dendritischen zellen und deren anwendungen | |
| ATE450546T1 (de) | Impfstoffe mit ornithobakterium rhinotracheale- untereinheit | |
| ATE423200T1 (de) | Neues plexin-polypeptid, dieses codierende dna und verwendung davon | |
| WO2004013281A3 (en) | Novel proteins and their uses | |
| HK1161887A (en) | Extended recombinant polypeptides and compositions comprising same |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B06T | Formal requirements before examination [chapter 6.20 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL |