CN1829916B - 用于确定生物活性分子之间结合的磁性粒子的使用 - Google Patents

用于确定生物活性分子之间结合的磁性粒子的使用 Download PDF

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Publication number
CN1829916B
CN1829916B CN2004800221615A CN200480022161A CN1829916B CN 1829916 B CN1829916 B CN 1829916B CN 2004800221615 A CN2004800221615 A CN 2004800221615A CN 200480022161 A CN200480022161 A CN 200480022161A CN 1829916 B CN1829916 B CN 1829916B
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magnetic
particle
pearl
molecule
microbial
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Expired - Fee Related
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CN2004800221615A
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CN1829916A (zh
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M·W·J·普林斯
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Koninklijke Philips NV
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Koninklijke Philips Electronics NV
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CN2004800221615A 2003-07-30 2004-07-14 用于确定生物活性分子之间结合的磁性粒子的使用 Expired - Fee Related CN1829916B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP03102352.6 2003-07-30
EP03102352 2003-07-30
PCT/IB2004/051213 WO2005010527A1 (en) 2003-07-30 2004-07-14 Use of magnetic particles for determining binding between bioactive molecules

Publications (2)

Publication Number Publication Date
CN1829916A CN1829916A (zh) 2006-09-06
CN1829916B true CN1829916B (zh) 2010-09-29

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CN2004800221615A Expired - Fee Related CN1829916B (zh) 2003-07-30 2004-07-14 用于确定生物活性分子之间结合的磁性粒子的使用

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US (1) US20060205093A1 (enExample)
EP (1) EP1651960A1 (enExample)
JP (1) JP4607875B2 (enExample)
KR (1) KR20060052889A (enExample)
CN (1) CN1829916B (enExample)
WO (1) WO2005010527A1 (enExample)

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US10914698B2 (en) 2006-11-16 2021-02-09 General Electric Company Sensing method and system
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US9536122B2 (en) 2014-11-04 2017-01-03 General Electric Company Disposable multivariable sensing devices having radio frequency based sensors
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EP2235504A1 (en) * 2007-12-20 2010-10-06 Koninklijke Philips Electronics N.V. Positioning of magnetic coils in a sensor device
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CA2711956A1 (en) 2008-01-17 2009-07-23 The Regents Of The University Of California Integrated magnetic field generation and detection platform
CN101939646B (zh) 2008-02-06 2014-05-14 皇家飞利浦电子股份有限公司 用于ftir生物传感器的使用反馈的磁珠致动
US8053250B2 (en) * 2008-06-27 2011-11-08 Rex Chin-Yih Hong Method and system for suppressing bindings on magnetic particles
GB0815212D0 (en) * 2008-08-20 2008-09-24 Roar Particles Ltd Identification of sample components
WO2010049883A1 (en) * 2008-10-31 2010-05-06 Koninklijke Philips Electronics N.V. Biosensor with multi-chamber cartridge
EP2368116B1 (en) * 2008-11-19 2019-07-03 Koninklijke Philips N.V. Biosensor system for actuating magnetic particles
US20120208296A1 (en) * 2009-08-19 2012-08-16 Koninklijke Philips Electronics N.V. Detection of different target components by cluster formation
DE102010013900B4 (de) * 2010-04-01 2013-01-03 Hochschule Für Angewandte Wissenschaften Fachhochschule Würzburg-Schweinfurt Verfahren zur Bildgebung mittels magnetischer Kleinstpartikel sowie Vorrichtung hierfür
US8542023B2 (en) 2010-11-09 2013-09-24 General Electric Company Highly selective chemical and biological sensors
US9518984B2 (en) * 2011-02-22 2016-12-13 Chrome Red Technologies, Llc Separation, washing and determination of analytes tagged with magnetic particles
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US10598650B2 (en) 2012-08-22 2020-03-24 General Electric Company System and method for measuring an operative condition of a machine
CN104583664B (zh) 2012-08-22 2018-06-08 通用电气公司 用于测量机器运转状况的无线系统和方法
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CN105190312B (zh) * 2013-03-01 2017-12-12 斯彼诺米克斯公司 基于磁性粒子的分离和测定方法
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CN107356758B (zh) * 2017-08-25 2019-11-22 李红俊 一种肺癌检测试剂盒及其使用方法
JP7212678B2 (ja) 2017-09-20 2023-01-25 アルトラテック・リミテッド 診断用デバイスおよびシステム
JP7158015B2 (ja) * 2017-11-09 2022-10-21 国立研究開発法人産業技術総合研究所 ポリペプチドの凝集化抑制方法
CN108192007A (zh) * 2017-12-28 2018-06-22 苏州英芮诚生化科技有限公司 一种羧基官能化的聚氨酯包覆磁性微球及其制备方法
CN111693691B (zh) * 2019-03-14 2023-09-05 天津华科泰生物技术有限公司 一种基于卟啉结构的聚合物标签
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JP2021115493A (ja) * 2020-01-22 2021-08-10 株式会社島津製作所 磁性体粒子の操作方法
CN114341641A (zh) * 2020-05-25 2022-04-12 金·保罗·杰里米 磁性纳米颗粒对于分析物的检测和定量的用途
CN114088680B (zh) * 2021-10-14 2023-06-27 安徽中科赛飞尔科技有限公司 一种染发样品中痕量毒品的快速检测方法

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Publication number Publication date
KR20060052889A (ko) 2006-05-19
JP2007500346A (ja) 2007-01-11
US20060205093A1 (en) 2006-09-14
WO2005010527A1 (en) 2005-02-03
JP4607875B2 (ja) 2011-01-05
CN1829916A (zh) 2006-09-06
EP1651960A1 (en) 2006-05-03

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