CN1826171A - 用于dna和蛋白质微阵列的可着色微球 - Google Patents

用于dna和蛋白质微阵列的可着色微球 Download PDF

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Publication number
CN1826171A
CN1826171A CNA2004800210324A CN200480021032A CN1826171A CN 1826171 A CN1826171 A CN 1826171A CN A2004800210324 A CNA2004800210324 A CN A2004800210324A CN 200480021032 A CN200480021032 A CN 200480021032A CN 1826171 A CN1826171 A CN 1826171A
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China
Prior art keywords
microspheres
microarray
analyte
reaction
biological
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Pending
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CNA2004800210324A
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English (en)
Chinese (zh)
Inventor
T·A·乔
J·W·莱昂
K·M·施勒德
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Eastman Kodak Co
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Eastman Kodak Co
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/583—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with non-fluorescent dye label
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00457—Dispensing or evacuation of the solid phase support
    • B01J2219/00459—Beads
    • B01J2219/00466—Beads in a slurry
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/0054—Means for coding or tagging the apparatus or the reagents
    • B01J2219/00545—Colours
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/0054—Means for coding or tagging the apparatus or the reagents
    • B01J2219/00572—Chemical means
    • B01J2219/00576—Chemical means fluorophore
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00646—Making arrays on substantially continuous surfaces the compounds being bound to beads immobilised on the solid supports
    • B01J2219/00648—Making arrays on substantially continuous surfaces the compounds being bound to beads immobilised on the solid supports by the use of solid beads
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00659—Two-dimensional arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • B01J2219/00722—Nucleotides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • B01J2219/00725—Peptides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • B01J2219/00731—Saccharides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
CNA2004800210324A 2003-07-23 2004-07-14 用于dna和蛋白质微阵列的可着色微球 Pending CN1826171A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/625,424 US20050019944A1 (en) 2003-07-23 2003-07-23 Colorable microspheres for DNA and protein microarray
US10/625,424 2003-07-23

Publications (1)

Publication Number Publication Date
CN1826171A true CN1826171A (zh) 2006-08-30

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Family Applications (1)

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CNA2004800210324A Pending CN1826171A (zh) 2003-07-23 2004-07-14 用于dna和蛋白质微阵列的可着色微球

Country Status (6)

Country Link
US (1) US20050019944A1 (https=)
EP (1) EP1646446A2 (https=)
JP (1) JP2006528773A (https=)
CN (1) CN1826171A (https=)
AU (1) AU2004265263A1 (https=)
WO (1) WO2005016515A2 (https=)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102791370A (zh) * 2010-03-17 2012-11-21 罗伯特·博世有限公司 具有固定粒子的微阵列
CN102853265A (zh) * 2011-06-30 2013-01-02 夏普株式会社 发光装置
CN103119178A (zh) * 2010-09-22 2013-05-22 株式会社钟化 核酸的检测方法以及装置、试剂盒
CN103823065A (zh) * 2014-03-13 2014-05-28 福建卫生职业技术学院 一种基于流式微球技术检测霉菌毒素的方法
US9476836B2 (en) 2011-03-04 2016-10-25 Kaneka Corporation Nucleic acid detection method, and device and kit for use in same
CN107632151A (zh) * 2017-07-28 2018-01-26 戈军 一种用于生物学检测、分析的固相材料
CN109112176A (zh) * 2018-09-04 2019-01-01 武汉尚码生物科技有限公司 一种微球编码载体及其应用
US20220066190A1 (en) * 2020-08-31 2022-03-03 Applied Materials, Inc. Slides for calibration of mfish

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CA2676432A1 (en) * 2007-01-18 2008-07-24 Sepracor, Inc. Inhibitors of d-amino acid oxidase
US20090029347A1 (en) * 2007-07-27 2009-01-29 Thornthwaite Jerry T Method for Identifying Multiple Analytes Using Flow Cytometry
US20130324478A1 (en) 2008-09-08 2013-12-05 Laurence Faure Pharmacodiagnosis Test Targeting Oncology and Neurodegeneration
WO2011028295A1 (en) * 2009-09-02 2011-03-10 Clear Align Llc Reversible reaction sensors and assemblies
CN102183512B (zh) * 2011-02-15 2012-09-19 杭州师范大学 一种基于化学发光原理的活细胞检测方法
EP2751134A1 (fr) 2011-03-18 2014-07-09 Laurence Faure Tests dedies a l'oncologie et a la neuro oncologie
US10443440B2 (en) * 2015-04-09 2019-10-15 United Technologies Corporation Heat shield, systems and methods
CN105689028B (zh) * 2016-01-20 2018-06-19 中国科学院上海微系统与信息技术研究所 用于免疫微球单一分布的微流体芯片、方法及其应用
CN111665235A (zh) * 2019-03-08 2020-09-15 上海索昕生物科技有限公司 一种化学发光微阵列芯片及其应用
CN111665236A (zh) * 2019-03-08 2020-09-15 上海索昕生物科技有限公司 一种发光微阵列芯片的制备方法及其应用
CN111665237A (zh) * 2019-03-08 2020-09-15 上海索昕生物科技有限公司 一种均相化学发光检测方法及其应用
CN118150554A (zh) * 2019-03-08 2024-06-07 上海索昕生物科技有限公司 一种化学发光微阵列芯片的应用
US20220276235A1 (en) * 2019-07-18 2022-09-01 Essenlix Corporation Imaging based homogeneous assay
JP7521846B1 (ja) 2023-10-02 2024-07-24 株式会社エンザイム・センサ 比色分析用高吸水性ポリマー及びそれを用いた分析方法

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US4663277A (en) * 1983-05-20 1987-05-05 Profile Diagnostic Sciences Inc. Virus detection method and materials
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US5143854A (en) * 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
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Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102791370A (zh) * 2010-03-17 2012-11-21 罗伯特·博世有限公司 具有固定粒子的微阵列
CN102791370B (zh) * 2010-03-17 2016-08-17 罗伯特·博世有限公司 具有固定粒子的微阵列
CN103119178A (zh) * 2010-09-22 2013-05-22 株式会社钟化 核酸的检测方法以及装置、试剂盒
US9097718B2 (en) 2010-09-22 2015-08-04 Kaneka Corporation Method and device for detecting nucleic acid, and kit
CN103119178B (zh) * 2010-09-22 2017-05-17 株式会社钟化 核酸的检测方法以及装置、试剂盒
US9476836B2 (en) 2011-03-04 2016-10-25 Kaneka Corporation Nucleic acid detection method, and device and kit for use in same
CN102853265A (zh) * 2011-06-30 2013-01-02 夏普株式会社 发光装置
CN103823065A (zh) * 2014-03-13 2014-05-28 福建卫生职业技术学院 一种基于流式微球技术检测霉菌毒素的方法
CN107632151A (zh) * 2017-07-28 2018-01-26 戈军 一种用于生物学检测、分析的固相材料
CN107632151B (zh) * 2017-07-28 2019-07-19 J.G.戈军 一种用于生物学检测、分析的固相材料
CN109112176A (zh) * 2018-09-04 2019-01-01 武汉尚码生物科技有限公司 一种微球编码载体及其应用
US20220066190A1 (en) * 2020-08-31 2022-03-03 Applied Materials, Inc. Slides for calibration of mfish

Also Published As

Publication number Publication date
JP2006528773A (ja) 2006-12-21
EP1646446A2 (en) 2006-04-19
AU2004265263A1 (en) 2005-02-24
US20050019944A1 (en) 2005-01-27
WO2005016515A2 (en) 2005-02-24
WO2005016515A3 (en) 2005-06-16

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