CN1819843A - 增强脑膜炎球菌疫苗接种免疫原性的方法 - Google Patents
增强脑膜炎球菌疫苗接种免疫原性的方法 Download PDFInfo
- Publication number
- CN1819843A CN1819843A CNA2004800193051A CN200480019305A CN1819843A CN 1819843 A CN1819843 A CN 1819843A CN A2004800193051 A CNA2004800193051 A CN A2004800193051A CN 200480019305 A CN200480019305 A CN 200480019305A CN 1819843 A CN1819843 A CN 1819843A
- Authority
- CN
- China
- Prior art keywords
- sba
- days
- serogroup
- titers
- vaccine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/05—Actinobacteria, e.g. Actinomyces, Streptomyces, Nocardia, Bifidobacterium, Gardnerella, Corynebacterium; Propionibacterium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/08—Clostridium, e.g. Clostridium tetani
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46858303P | 2003-05-07 | 2003-05-07 | |
| US60/468,583 | 2003-05-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1819843A true CN1819843A (zh) | 2006-08-16 |
Family
ID=34061894
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2004800193051A Pending CN1819843A (zh) | 2003-05-07 | 2004-05-07 | 增强脑膜炎球菌疫苗接种免疫原性的方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20050002948A1 (enExample) |
| EP (2) | EP1626737A2 (enExample) |
| JP (2) | JP2007516219A (enExample) |
| CN (1) | CN1819843A (enExample) |
| AU (2) | AU2004255526A1 (enExample) |
| BR (1) | BRPI0410423A (enExample) |
| CA (1) | CA2524853A1 (enExample) |
| WO (1) | WO2005004909A2 (enExample) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102462839A (zh) * | 2010-11-12 | 2012-05-23 | 北京生物制品研究所 | 多糖结合疫苗及其制备方法 |
| CN103100081A (zh) * | 2012-12-26 | 2013-05-15 | 天津康希诺生物技术有限公司 | 一种多价联合疫苗 |
| CN106167519A (zh) * | 2016-08-10 | 2016-11-30 | 成都生物制品研究所有限责任公司 | 一种破伤风类毒素的制备方法 |
| CN107674118A (zh) * | 2016-08-02 | 2018-02-09 | 中国食品药品检定研究院 | 重组蛋白PspA1、PspA2和PspA3以及包含其的多糖结合疫苗 |
| CN109402035A (zh) * | 2018-11-06 | 2019-03-01 | 华中农业大学 | 一种肠外致病性大肠杆菌重组菌株及其应用 |
| CN111024946A (zh) * | 2019-11-19 | 2020-04-17 | 江苏美克医学技术有限公司 | 阴道毛滴虫荧光免疫层析测定试剂盒及其制备方法 |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE279943T1 (de) * | 1999-02-26 | 2004-11-15 | Chiron Srl | Verbesserung der bakterizidaktivität von neisseria antigenen mit cg enthaltende oligonukleotiden |
| GB0406013D0 (en) * | 2004-03-17 | 2004-04-21 | Chiron Srl | Analysis of saccharide vaccines without interference |
| GB0500787D0 (en) * | 2005-01-14 | 2005-02-23 | Chiron Srl | Integration of meningococcal conjugate vaccination |
| NZ550533A (en) * | 2004-04-30 | 2010-02-26 | Novartis Vaccines & Diagnostic | Meningococcal conjugate vaccination comprising N. meningitidis and diphtheria toxin |
| WO2006026689A2 (en) * | 2004-08-30 | 2006-03-09 | Sanofi Pasteur, Inc. | Multivalent meningococcal derivatized polysaccharide-protein conjugates and vaccine |
| ES2443529T3 (es) | 2005-09-01 | 2014-02-19 | Novartis Vaccines And Diagnostics Gmbh | Vacunación múltiple incluyendo meningococo del serogrupo C |
| BRPI0516372A (pt) * | 2005-12-22 | 2008-09-02 | Sanofi Pasteur Inc | conjugados de polissacarìdeo-proteìna derivatizados meningocócicos multivalentes e vacina |
| US20080305127A1 (en) * | 2005-12-23 | 2008-12-11 | Glaxosmithkline Biologicals S.A. | Conjugate Vaccines |
| KR20150038626A (ko) | 2006-03-17 | 2015-04-08 | 더 거버먼트 오브 더 유나이티드 스테이츠 오브 아메리카 에즈 레프리젠티드 바이 더 세크러테리 오브 더 디파트먼트 오브 헬스 앤드 휴먼 서비시즈 | 복합 다가 면역원성 콘쥬게이트의 제조 방법 |
| US8414899B2 (en) | 2006-04-11 | 2013-04-09 | Yeda Research And Development Co. Ltd. | Vaccines comprising multimeric HSP60 peptide carriers |
| US7491517B2 (en) | 2006-07-19 | 2009-02-17 | Jeeri R Reddy | Method of producing meningococcal meningitis vaccine for Neisseria meningitidis serotypes A,C,Y, and W-135 |
| US8394391B2 (en) * | 2007-08-31 | 2013-03-12 | University Of Utah Research Foundation | Drug delivery vehicle that mimics viral properties |
| GB0822633D0 (en) | 2008-12-11 | 2009-01-21 | Novartis Ag | Formulation |
| US8003112B2 (en) * | 2009-04-16 | 2011-08-23 | Howard University | Meningococcal and pneumococcal conjugate vaccine and method of using same |
| US8926982B2 (en) * | 2009-06-01 | 2015-01-06 | Xuguang Li | Reagents and methods for detecting influenza virus proteins |
| EP2550289A4 (en) | 2010-03-12 | 2013-11-27 | Childrens Medical Center | NEW IMMUNOGENES AND METHODS FOR IDENTIFICATION AND SCREENING THEREOF |
| CA2800158C (en) * | 2010-05-28 | 2020-07-21 | Coley Pharmaceutical Group, Inc. | Vaccines comprising cholesterol and cpg as sole adjuvant-carrier molecules |
| US10766932B2 (en) | 2011-05-11 | 2020-09-08 | The Children's Medical Center Corporation | Multiple antigen presenting immunogenic composition, and methods and uses thereof |
| US10428955B2 (en) * | 2012-06-25 | 2019-10-01 | Hamilton Sundstrand Corporation | Contamination resistant butterfly valve |
| JP6494527B2 (ja) | 2013-02-07 | 2019-04-03 | ザ チルドレンズ メディカル センター コーポレーション | 肺炎球菌のコロニー形成および/または疾患からの保護を提供するタンパク質抗原 |
| CA3061709A1 (en) | 2017-03-28 | 2018-10-04 | The Children's Medical Center Corporation | A multiple antigen presenting system (maps)-based staphylococcus aureus vaccine, immunogenic composition, and uses thereof |
| BR112019027387A8 (pt) | 2017-06-23 | 2022-12-06 | Univ Maryland | Composições imunogênicas |
| TWI852943B (zh) | 2018-09-12 | 2024-08-21 | 美商兒童醫療中心公司 | 肺炎鏈球菌融合蛋白疫苗 |
| JP2021535921A (ja) | 2018-09-12 | 2021-12-23 | アフィニバックス、インコーポレイテッド | 多価肺炎球菌ワクチン |
| CN115605222A (zh) | 2019-09-27 | 2023-01-13 | 辉瑞公司(Us) | 脑膜炎奈瑟氏菌组合物及其方法 |
| IL311239A (en) | 2021-09-09 | 2024-05-01 | Affinivax Inc | Multivalent pneumococcal vaccines |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4356170A (en) | 1981-05-27 | 1982-10-26 | Canadian Patents & Development Ltd. | Immunogenic polysaccharide-protein conjugates |
| US4619828A (en) | 1982-07-06 | 1986-10-28 | Connaught Laboratories, Inc. | Polysaccharide exotoxoid conjugate vaccines |
| HU212924B (en) | 1989-05-25 | 1996-12-30 | Chiron Corp | Adjuvant formulation comprising a submicron oil droplet emulsion |
| US5153312A (en) | 1990-09-28 | 1992-10-06 | American Cyanamid Company | Oligosaccharide conjugate vaccines |
| US5422427A (en) | 1991-09-17 | 1995-06-06 | The United States Of America As Represented By The United States Department Of Health And Human Services | Pneumococcal fimbrial protein A |
| US5445817A (en) | 1992-08-21 | 1995-08-29 | The United States Of America As Represented By The Department Of Health And Human Services | Pertussis toxin used as a carrier protein with non-charged saccharides in conjugate vaccines |
| US5965714A (en) | 1997-10-02 | 1999-10-12 | Connaught Laboratories, Inc. | Method for the covalent attachment of polysaccharides to protein molecules |
| US6146902A (en) | 1998-12-29 | 2000-11-14 | Aventis Pasteur, Inc. | Purification of polysaccharide-protein conjugate vaccines by ultrafiltration with ammonium sulfate solutions |
| GB0108364D0 (en) | 2001-04-03 | 2001-05-23 | Glaxosmithkline Biolog Sa | Vaccine composition |
| KR100898845B1 (ko) | 2000-06-29 | 2009-05-21 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 다가 백신 조성물 |
| YU66103A (sh) * | 2001-01-23 | 2006-05-25 | Aventis Pasteur | Vakcina multivalentnog konjugata meningokokalnog polisaharid-proteina |
-
2004
- 2004-05-07 CA CA002524853A patent/CA2524853A1/en not_active Abandoned
- 2004-05-07 WO PCT/US2004/014337 patent/WO2005004909A2/en not_active Ceased
- 2004-05-07 AU AU2004255526A patent/AU2004255526A1/en not_active Abandoned
- 2004-05-07 EP EP04775955A patent/EP1626737A2/en not_active Withdrawn
- 2004-05-07 US US10/841,267 patent/US20050002948A1/en not_active Abandoned
- 2004-05-07 JP JP2006529367A patent/JP2007516219A/ja active Pending
- 2004-05-07 EP EP10185661A patent/EP2301571A1/en not_active Withdrawn
- 2004-05-07 BR BRPI0410423-4A patent/BRPI0410423A/pt not_active IP Right Cessation
- 2004-05-07 CN CNA2004800193051A patent/CN1819843A/zh active Pending
-
2010
- 2010-12-21 AU AU2010257354A patent/AU2010257354A1/en not_active Withdrawn
- 2010-12-22 JP JP2010285610A patent/JP2011068676A/ja active Pending
Non-Patent Citations (1)
| Title |
|---|
| WILLIAMS&WILKINS,BALTIMORE,: "DOSE ESCALATION,SAFETY AND IMMUNOGENICITY STUDY OF A TETRAVALENT MENINGOCOCCAL POLYSACCHARIDE DIPHTHERIA CONJUGATE VACCINE IN TODDLERS", 《PEDIATRIC INFECTIOUS DISEASE JOURNAL》 * |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102462839A (zh) * | 2010-11-12 | 2012-05-23 | 北京生物制品研究所 | 多糖结合疫苗及其制备方法 |
| CN102462839B (zh) * | 2010-11-12 | 2016-03-30 | 北京生物制品研究所 | 多糖结合疫苗及其制备方法 |
| CN103100081A (zh) * | 2012-12-26 | 2013-05-15 | 天津康希诺生物技术有限公司 | 一种多价联合疫苗 |
| CN107674118A (zh) * | 2016-08-02 | 2018-02-09 | 中国食品药品检定研究院 | 重组蛋白PspA1、PspA2和PspA3以及包含其的多糖结合疫苗 |
| CN106167519A (zh) * | 2016-08-10 | 2016-11-30 | 成都生物制品研究所有限责任公司 | 一种破伤风类毒素的制备方法 |
| CN109402035A (zh) * | 2018-11-06 | 2019-03-01 | 华中农业大学 | 一种肠外致病性大肠杆菌重组菌株及其应用 |
| CN111024946A (zh) * | 2019-11-19 | 2020-04-17 | 江苏美克医学技术有限公司 | 阴道毛滴虫荧光免疫层析测定试剂盒及其制备方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2010257354A1 (en) | 2011-01-20 |
| WO2005004909A2 (en) | 2005-01-20 |
| US20050002948A1 (en) | 2005-01-06 |
| EP1626737A2 (en) | 2006-02-22 |
| CA2524853A1 (en) | 2005-01-20 |
| JP2007516219A (ja) | 2007-06-21 |
| WO2005004909A3 (en) | 2005-06-02 |
| AU2004255526A1 (en) | 2005-01-20 |
| BRPI0410423A (pt) | 2006-06-06 |
| EP2301571A1 (en) | 2011-03-30 |
| JP2011068676A (ja) | 2011-04-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN1819843A (zh) | 增强脑膜炎球菌疫苗接种免疫原性的方法 | |
| CN1852733A (zh) | 多价脑膜炎球菌衍生的多糖-蛋白质缀合物及疫苗 | |
| CN1191852C (zh) | 疫苗 | |
| CN100350972C (zh) | 含有铝佐剂和组氨酸的疫苗 | |
| CN1582297A (zh) | 奈瑟球菌蛋白质的杂合和串联表达 | |
| CN1767853A (zh) | 粘膜脑膜炎球菌疫苗 | |
| CN1946420A (zh) | 利用蛋白质进行针对脑膜炎球菌血清群y的免疫 | |
| CN1684707A (zh) | 用于细菌性脑膜炎的粘膜结合疫苗 | |
| CN1882612A (zh) | 乙酰化过低和过高的脑膜炎球菌荚膜糖 | |
| CN1809380A (zh) | 广泛防御高毒性脑膜炎球菌谱系的多肽-疫苗 | |
| CN101031584A (zh) | 脑膜炎球菌蛋白nmb1870的结构域和表位 | |
| CN101048175A (zh) | 具有外膜蛋白的免疫原性细菌囊泡 | |
| CN1228709A (zh) | 多价dtp-polio疫苗 | |
| US20090181054A1 (en) | Multivalent meningococcal derivatized polysaccharide-protein conjugates and vaccine | |
| CN101048177A (zh) | 多价的脑膜炎球菌产生的多糖-蛋白质偶联物和疫苗 | |
| EP2345422A1 (en) | Multivalent meningococcal derivatized polysaccharide-protein conjugates and vaccine | |
| CN1993141A (zh) | 诱导针对肺炎链球菌多糖的免疫应答 | |
| HK1096856A (en) | Method of enhanced immunogenicity to meningococcal vaccination | |
| HK1096305A (en) | Multivalent meningococcal derivatized polysaccharide-protein conjugates and corresponding vaccines | |
| CN1889975A (zh) | 多种脑膜炎球菌血清群的液体疫苗 | |
| AU2014213504B2 (en) | Multivalent meningococcal derivatized polysaccharide-protein conjugates and corresponding vaccines | |
| CN1976724A (zh) | 脑膜炎球菌缀合物疫苗的整合 | |
| CN1764472A (zh) | 抗多种脑膜炎球菌血清组的可注射性疫苗 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| REG | Reference to a national code |
Ref country code: HK Ref legal event code: DE Ref document number: 1096856 Country of ref document: HK |
|
| C12 | Rejection of a patent application after its publication | ||
| RJ01 | Rejection of invention patent application after publication |
Open date: 20060816 |
|
| CI01 | Publication of corrected invention patent application |
Correction item: Rejection of patent application Correct: Dismiss False: Reject Number: 32 Volume: 26 |
|
| ERR | Gazette correction |
Free format text: CORRECT: PATENT APPLICATION REJECTION AFTER THE ANNOUNCEMENT; FROM: REJECTION TO: CANCEL REJECTION |
|
| REG | Reference to a national code |
Ref country code: HK Ref legal event code: WD Ref document number: 1096856 Country of ref document: HK |
|
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20060816 |
|
| WD01 | Invention patent application deemed withdrawn after publication |