CN1805738A - 持续释放的二甲双胍片剂 - Google Patents

持续释放的二甲双胍片剂 Download PDF

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Publication number
CN1805738A
CN1805738A CNA2004800167682A CN200480016768A CN1805738A CN 1805738 A CN1805738 A CN 1805738A CN A2004800167682 A CNA2004800167682 A CN A2004800167682A CN 200480016768 A CN200480016768 A CN 200480016768A CN 1805738 A CN1805738 A CN 1805738A
Authority
CN
China
Prior art keywords
tablet
continuous release
release tablet
metformin
cellulose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2004800167682A
Other languages
English (en)
Chinese (zh)
Inventor
M·查拉
R·S·拉古瓦希
A·兰帕尔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ranbaxy Laboratories Ltd
Original Assignee
Ranbaxy Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ranbaxy Laboratories Ltd filed Critical Ranbaxy Laboratories Ltd
Publication of CN1805738A publication Critical patent/CN1805738A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
CNA2004800167682A 2003-06-16 2004-06-14 持续释放的二甲双胍片剂 Pending CN1805738A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN805DE2003 2003-06-16
IN805/DEL/2003 2003-06-16

Publications (1)

Publication Number Publication Date
CN1805738A true CN1805738A (zh) 2006-07-19

Family

ID=33548811

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2004800167682A Pending CN1805738A (zh) 2003-06-16 2004-06-14 持续释放的二甲双胍片剂

Country Status (3)

Country Link
EP (1) EP1646374A1 (de)
CN (1) CN1805738A (de)
WO (1) WO2004110422A1 (de)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102711739A (zh) * 2009-11-13 2012-10-03 百时美施贵宝公司 双层片剂
CN111939135A (zh) * 2020-09-02 2020-11-17 苏州东瑞制药有限公司 一种盐酸二甲双胍药物的缓释片及其制备方法

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KR100772980B1 (ko) * 2004-04-01 2007-11-02 한미약품 주식회사 메트포르민의 경구투여용 서방성 제제
SI1878426T1 (sl) * 2005-04-26 2010-09-30 Dainippon Sumitomo Pharma Co Granulatni pripravek ki vsebuje bigvanidno spojino
JOP20180109A1 (ar) * 2005-09-29 2019-01-30 Novartis Ag تركيبة جديدة
CA2632607A1 (en) * 2005-12-09 2007-06-21 Metaproteomics, Llc Anti-inflammatory botanical products for the treatment of metabolic syndrome and diabetes
US8703191B2 (en) 2006-07-25 2014-04-22 Intelgenx Corp. Controlled-release pharmaceutical tablets
US7674479B2 (en) 2006-07-25 2010-03-09 Intelgenx Corp. Sustained-release bupropion and bupropion/mecamylamine tablets
JP2010521492A (ja) * 2007-03-15 2010-06-24 ネクティド，インク． 徐放性ビグアニド組成物、および即時性ジペプチジルペプチダーゼｉｖ阻害剤組成物を含む抗糖尿病合剤
US8551524B2 (en) 2008-03-14 2013-10-08 Iycus, Llc Anti-diabetic combinations
US20120294936A1 (en) * 2009-11-13 2012-11-22 Astrazeneca Uk Limited Reduced mass metformin formulations
US20110136815A1 (en) 2009-12-08 2011-06-09 Horst Zerbe Solid oral film dosage forms and methods for making same
US10610528B2 (en) 2009-12-08 2020-04-07 Intelgenx Corp. Solid oral film dosage forms and methods for making same
US9480663B2 (en) 2011-01-07 2016-11-01 Elcelyx Therapeutics, Inc. Biguanide compositions and methods of treating metabolic disorders
US20120177730A1 (en) 2011-01-07 2012-07-12 Elcelyx Therapeutics, Inc. Chemosensory Receptor Ligand-Based Therapies
US11759441B2 (en) 2011-01-07 2023-09-19 Anji Pharmaceuticals Inc. Biguanide compositions and methods of treating metabolic disorders
US11974971B2 (en) 2011-01-07 2024-05-07 Anji Pharmaceuticals Inc. Compositions and methods for treating metabolic disorders
US8796338B2 (en) 2011-01-07 2014-08-05 Elcelyx Therapeutics, Inc Biguanide compositions and methods of treating metabolic disorders
US9572784B2 (en) 2011-01-07 2017-02-21 Elcelyx Therapeutics, Inc. Compositions comprising statins, biguanides and further agents for reducing cardiometabolic risk
US9211263B2 (en) 2012-01-06 2015-12-15 Elcelyx Therapeutics, Inc. Compositions and methods of treating metabolic disorders
AU2012363873B2 (en) 2012-01-06 2017-11-23 Anji Pharmaceuticals Inc. Biguanide compositions and methods of treating metabolic disorders
JP6175074B2 (ja) 2012-01-06 2017-08-02 エルセリクス セラピューティクス インコーポレイテッド 代謝障害を治療するための組成物および方法
US10166246B2 (en) 2014-05-27 2019-01-01 City Of Hope TGR5 agonist complexes for treating diabetes and cancer
WO2016042567A1 (en) * 2014-09-16 2016-03-24 Suresh Pareek Extended release formulation of metformin
TW201938147A (zh) * 2017-12-18 2019-10-01 德商拜耳廠股份有限公司 阿卡波糖與甲福明之固定劑量組合錠劑配製物及其製法
JP7376582B2 (ja) * 2018-10-22 2023-11-08 イーオーイー オレオ ゲーエムベーハー 成形体への圧縮を目的とした粉末材料用添加剤

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4432757A1 (de) * 1994-09-14 1996-03-21 Boehringer Mannheim Gmbh Pharmazeutische Zubereitung enthaltend Metformin und Verfahren zu deren Herstellung
US6117451A (en) * 1998-08-25 2000-09-12 Pharmalogix, Inc. Direct compression metformin hydrochloride tablets
EP1322158B1 (de) * 2000-10-02 2012-08-08 USV Ltd. Metformin enthaltende pharmazeutische Zusammensetzungen mit verzögerter Wirkstofffreigabe und Verfahren zu deren Herstellung
IN192180B (de) * 2001-09-28 2004-03-06 Ranbaxy Lab
JP2005508331A (ja) * 2001-09-28 2005-03-31 サン・ファーマシューティカル・インダストリーズ・リミテッド 糖尿病の処置のための投与製剤
CN1700910A (zh) * 2001-11-06 2005-11-23 兰贝克赛实验室有限公司 甲福明控释片剂
US6667054B2 (en) * 2001-12-05 2003-12-23 Bernard Charles Sherman Metformin hydrochloride tablets

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102711739A (zh) * 2009-11-13 2012-10-03 百时美施贵宝公司 双层片剂
CN102711739B (zh) * 2009-11-13 2015-12-16 阿斯利康(瑞典)有限公司 双层片剂
CN105193761A (zh) * 2009-11-13 2015-12-30 阿斯利康(瑞典)有限公司 双层片剂
CN105193761B (zh) * 2009-11-13 2019-12-06 阿斯利康(瑞典)有限公司 双层片剂
CN111939135A (zh) * 2020-09-02 2020-11-17 苏州东瑞制药有限公司 一种盐酸二甲双胍药物的缓释片及其制备方法

Also Published As

Publication number Publication date
EP1646374A1 (de) 2006-04-19
WO2004110422A1 (en) 2004-12-23

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