CN1772742A - 高纯度2,6－二氯喹喔啉的制备方法 - Google Patents
高纯度2,6－二氯喹喔啉的制备方法 Download PDFInfo
- Publication number
- CN1772742A CN1772742A CN 200510095624 CN200510095624A CN1772742A CN 1772742 A CN1772742 A CN 1772742A CN 200510095624 CN200510095624 CN 200510095624 CN 200510095624 A CN200510095624 A CN 200510095624A CN 1772742 A CN1772742 A CN 1772742A
- Authority
- CN
- China
- Prior art keywords
- dichloro
- organic solvent
- preparation
- high purity
- quinozaline
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- WFOKVKYNVKVWFK-UHFFFAOYSA-N 2,6-dichloroquinoxaline Chemical compound N1=C(Cl)C=NC2=CC(Cl)=CC=C21 WFOKVKYNVKVWFK-UHFFFAOYSA-N 0.000 title claims description 4
- 238000000034 method Methods 0.000 title abstract description 4
- 238000002360 preparation method Methods 0.000 claims abstract description 13
- 239000003960 organic solvent Substances 0.000 claims abstract description 9
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 8
- 239000002904 solvent Substances 0.000 claims abstract description 6
- 238000003756 stirring Methods 0.000 claims abstract description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 5
- 239000007788 liquid Substances 0.000 claims abstract description 4
- 239000000376 reactant Substances 0.000 claims abstract description 3
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Natural products CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 claims description 13
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 6
- XHXFXVLFKHQFAL-UHFFFAOYSA-N phosphoryl trichloride Chemical compound ClP(Cl)(Cl)=O XHXFXVLFKHQFAL-UHFFFAOYSA-N 0.000 claims description 4
- FYSNRJHAOHDILO-UHFFFAOYSA-N thionyl chloride Chemical group ClS(Cl)=O FYSNRJHAOHDILO-UHFFFAOYSA-N 0.000 claims description 3
- 238000010792 warming Methods 0.000 claims description 3
- LTHQFFWUHBKRGG-UHFFFAOYSA-N 3-chloro-1h-quinoxalin-2-one Chemical class C1=CC=C2N=C(Cl)C(O)=NC2=C1 LTHQFFWUHBKRGG-UHFFFAOYSA-N 0.000 claims description 2
- 235000011121 sodium hydroxide Nutrition 0.000 claims description 2
- 125000003944 tolyl group Chemical group 0.000 claims description 2
- 238000005516 engineering process Methods 0.000 abstract description 3
- 238000001914 filtration Methods 0.000 abstract description 2
- 239000012847 fine chemical Substances 0.000 abstract description 2
- 238000010992 reflux Methods 0.000 abstract description 2
- 230000001105 regulatory effect Effects 0.000 abstract description 2
- 239000003054 catalyst Substances 0.000 abstract 1
- 239000012320 chlorinating reagent Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000001704 evaporation Methods 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 239000000575 pesticide Substances 0.000 abstract 1
- 239000003905 agrochemical Substances 0.000 description 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 2
- 238000007599 discharging Methods 0.000 description 2
- 239000012452 mother liquor Substances 0.000 description 2
- SJAZZQLTKBYDHN-UHFFFAOYSA-N 6-chloro-1h-quinoxalin-2-one Chemical class C1=C(Cl)C=CC2=NC(O)=CN=C21 SJAZZQLTKBYDHN-UHFFFAOYSA-N 0.000 description 1
- 241000628997 Flos Species 0.000 description 1
- WXIUBYCJAAEOFL-UHFFFAOYSA-N [S].ClOCl Chemical class [S].ClOCl WXIUBYCJAAEOFL-UHFFFAOYSA-N 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 235000021050 feed intake Nutrition 0.000 description 1
- 238000009413 insulation Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Landscapes
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Description
Claims (4)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005100956247A CN100345831C (zh) | 2005-11-10 | 2005-11-10 | 高纯度2,6－二氯喹喔啉的制备方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005100956247A CN100345831C (zh) | 2005-11-10 | 2005-11-10 | 高纯度2,6－二氯喹喔啉的制备方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1772742A true CN1772742A (zh) | 2006-05-17 |
| CN100345831C CN100345831C (zh) | 2007-10-31 |
Family
ID=36759903
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2005100956247A Active CN100345831C (zh) | 2005-11-10 | 2005-11-10 | 高纯度2,6－二氯喹喔啉的制备方法 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN100345831C (zh) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101914069A (zh) * | 2010-07-29 | 2010-12-15 | 安徽丰乐农化有限责任公司 | 6-氯-2-羟基喹喔啉的氯化新工艺 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EG11837A (en) * | 1974-09-19 | 1977-12-31 | Lilly Co Eli | Novel 1-(substituted benzoyl)-3-(substituted pyrazinyl ureas used as insecticides |
| DE2724624C2 (de) * | 1977-06-01 | 1985-07-25 | Carl Schenck Ag, 6100 Darmstadt | Verfahren zum Eindrehen eines mit Unwucht behafteten Rotationskörpers |
| US4636562A (en) * | 1982-05-07 | 1987-01-13 | E. I. Du Pont De Nemours And Company | Process for preparing 6-halo-2-chloroquinoxaline |
| EP0113831A3 (de) * | 1982-12-17 | 1984-11-07 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft | Carbaminsäureester, Verfahren zu deren Herstellung und deren Verwendung |
| DE3925969A1 (de) * | 1989-08-05 | 1991-02-07 | Hoechst Ag | Verfahren zur herstellung von 2,6-dichlorchinoxalin |
| US5529999A (en) * | 1994-03-04 | 1996-06-25 | Eli Lilly And Company | Antitumor compositions and methods of treatment |
-
2005
- 2005-11-10 CN CNB2005100956247A patent/CN100345831C/zh active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101914069A (zh) * | 2010-07-29 | 2010-12-15 | 安徽丰乐农化有限责任公司 | 6-氯-2-羟基喹喔啉的氯化新工艺 |
Also Published As
| Publication number | Publication date |
|---|---|
| CN100345831C (zh) | 2007-10-31 |
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Effective date of registration: 20090220 Address after: No. 4, Pioneer Road, Shushan Economic Development Zone, Anhui, Hefei Patentee after: Anhui Fengle Agrochemical Co., Ltd. Address before: Anhui city of Hefei Province Agricultural Company fan wa Road No. 8 Patentee before: Wu Yonghu |
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Owner name: ANHUI FENGLE AGRICULTURAL CO., LTD. Free format text: FORMER OWNER: WU YONGHU Effective date: 20090220 |
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Address after: 231602 Hefei circular economy demonstration garden, Feidong County, Anhui Province Patentee after: Anhui Fengle Agrochemical Co., Ltd. Address before: 230031 No. 4, Pioneer Road, Shushan Economic Development Zone, Anhui, Hefei Patentee before: Anhui Fengle Agrochemical Co., Ltd. |
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Denomination of invention: Process for preparing high-purity 2-methyl-4-chloro phenoxyacetic acid Effective date of registration: 20160809 Granted publication date: 20071031 Pledgee: Bank of Hangzhou, Limited by Share Ltd, Feidong branch Pledgor: Anhui Fengle Agrochemical Co., Ltd. Registration number: 2016340000042 |
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Date of cancellation: 20170803 Granted publication date: 20071031 Pledgee: Bank of Hangzhou, Limited by Share Ltd, Feidong branch Pledgor: Anhui Fengle Agrochemical Co., Ltd. Registration number: 2016340000042 |
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| PC01 | Cancellation of the registration of the contract for pledge of patent right | ||
| PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: Process for preparing high-purity 2-methyl-4-chloro phenoxyacetic acid Effective date of registration: 20170814 Granted publication date: 20071031 Pledgee: Bank of Hangzhou, Limited by Share Ltd, Feidong branch Pledgor: Anhui Fengle Agrochemical Co., Ltd. Registration number: 2017340000151 |
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Date of cancellation: 20170818 Granted publication date: 20071031 Pledgee: Bank of Hangzhou, Limited by Share Ltd, Feidong branch Pledgor: Anhui Fengle Agrochemical Co., Ltd. Registration number: 2017340000151 |
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Denomination of invention: Process for preparing high-purity 2-methyl-4-chloro phenoxyacetic acid Effective date of registration: 20170828 Granted publication date: 20071031 Pledgee: Industrial Bank Limited by Share Ltd Hefei branch Pledgor: Anhui Fengle Agrochemical Co., Ltd. Registration number: 2017340000180 |
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Date of cancellation: 20190129 Granted publication date: 20071031 Pledgee: Industrial Bank Limited by Share Ltd Hefei branch Pledgor: Anhui Fengle Agrochemical Co., Ltd. Registration number: 2017340000180 |
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