CN1772311A - 一种含银锌组合物的创伤敷料 - Google Patents
一种含银锌组合物的创伤敷料 Download PDFInfo
- Publication number
- CN1772311A CN1772311A CN 200410090621 CN200410090621A CN1772311A CN 1772311 A CN1772311 A CN 1772311A CN 200410090621 CN200410090621 CN 200410090621 CN 200410090621 A CN200410090621 A CN 200410090621A CN 1772311 A CN1772311 A CN 1772311A
- Authority
- CN
- China
- Prior art keywords
- argentiferous
- composition
- zinc
- wound dressing
- silver
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
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- 229910052725 zinc Inorganic materials 0.000 claims abstract description 81
- 229910052709 silver Inorganic materials 0.000 claims abstract description 45
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- NDVLTYZPCACLMA-UHFFFAOYSA-N silver oxide Chemical compound [O-2].[Ag+].[Ag+] NDVLTYZPCACLMA-UHFFFAOYSA-N 0.000 claims abstract description 20
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- 150000003751 zinc Chemical class 0.000 claims abstract description 5
- 238000005507 spraying Methods 0.000 claims abstract description 3
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Abstract
Description
价态(化合物) | Ag% | Zn% | 对白色念珠菌杀菌率%(10分钟6.6×105cfu/ml) |
Ag+(AgNO3) | 0.01 | 0 | 87.31 |
Ag4+(H4Ag2O6) | 0.01 | 0 | 98.05 |
Ag4+(H4Ag2O6) | 0.01 | 1.0 | 99.99 |
氧化银 | 0.1 | 0 | 86.42 |
氧化银 | 0.1 | 1.0 | 98.91 |
过氧化银 | 0.1 | 0 | 90.10 |
过氧化银 | 0.1 | 1.0 | 99.80 |
NO | Ag%(Ag4+) | Zn% | 对白色念珠菌杀菌率%(10分钟5.25×105cfu/ml) |
1 | 0.01 | 0 | 97.45 |
2 | 0.01 | 0.01 | 99.72 |
3 | 0.01 | 0.03 | 99.95 |
4 | 0.01 | 0.05 | 99.91 |
5 | 0.01 | 0.10 | 99.85 |
6 | 0.01 | 0.20 | 99.57 |
7 | 0.01 | 0.30 | 98.10 |
8 | 0.01 | 0.50 | 97.70 |
9 | 0.01 | 1.0 | 97.30 |
敷料名称 | 吸苯率(wt%) |
以天然纤维或其纺织物、无纺布为载体的含银锌组合物的创伤敷料(实施例1) | 45-50 |
以甲壳胺纤维或其机织物、针织物、无纺布为载体的含银锌组合物的创伤敷料(实施例2) | 40-45 |
以藻酸盐纤维或其机织物、针织物、无纺布为载体的含银锌组合物的创伤敷料(实施例3) | 40-50 |
以甲壳胺纤维或其机织物、针织物、无纺布为载体的含银锌组合物的创伤敷料(实施例4) | 40-45 |
以藻酸盐纤维或其机织物、针织物、无纺布为载体的含银锌组合物的创伤敷料(实施例5) | 40-45 |
以活性炭纤维或其机织物、针织物、无纺布为载体的含银锌组合物的创伤敷料(实施例6) | 8-10 |
以活性炭纤维及其机织物、针织物、无纺布为载体的含银锌组合物的创伤敷料(实施例7) | 8-10 |
以活性炭粉末为载体的含银锌组合物的创伤敷料(实施例8) | 7-9 |
以聚氨酯泡沫塑料为载体的含银锌组合物的创伤敷料(实施例14) | 30-35 |
以聚乙烯泡沫塑料为载体的含银锌组合物的创伤敷料(实施例15) | 35-40 |
以聚苯乙烯泡沫塑料为载体的含银锌组合物的创伤敷料(实施例16) | 30-40 |
敷料种类 | 平均止血时间(s) |
以天然纤维或其纺织物、无纺布为载体的含银锌组合物的创伤敷料(实施例1) | 69 |
以甲壳胺纤维或其机织物、针织物、无纺布为载体的含银锌组合 | 46 |
物的创伤敷料(实施例2) | |
以藻酸盐纤维或其机织物、针织物、无纺布为载体的含银锌组合物的创伤敷料(实施例3) | 45 |
以甲壳胺纤维或其机织物、针织物、无纺布为载体的含银锌组合物的创伤敷料(实施例4) | 40 |
以藻酸盐纤维或其机织物、针织物、无纺布为载体的含银锌组合物的创伤敷料(实施例5) | 35 |
以活性炭纤维或其机织物、针织物、无纺布为载体的含银锌组合物的创伤敷料(实施例6) | 48 |
以活性炭纤维及其机织物、针织物、无纺布为载体的含银锌组合物的创伤敷料(实施例7) | 53 |
以活性炭粉末为载体的含银锌组合物的创伤敷料(实施例8) | 46 |
以聚氨酯泡沫塑料为载体的含银锌组合物的创伤敷料(实施例14) | 51 |
以聚乙烯泡沫塑料为载体的含银锌组合物的创伤敷料(实施例15) | 49 |
以聚苯乙烯泡沫塑料为载体的含银锌组合物的创伤敷料(实施例16) | 47 |
含银锌组合物的膨润土粉末止血敷料(实施例17) | 35 |
含银锌组合物的膨润土粉末止血敷料(实施例18) | 38 |
含银锌组合物的沸石粉末止血敷料(实施例19) | 35 |
含银锌组合物的沸石粉末止血敷料(实施例20) | 31 |
含银锌组合物的聚丙烯酸、羧甲基淀粉止血粉末敷料(实施例21) | 30 |
含银锌组合物的羟乙基纤维素、海藻酸钠止血粉末敷料(实施例22) | 31 |
观察项目 | 浅II度创面 | 深II度创面 | ||||||
实验组1 | 实验组2 | 实验组3 | 对照组 | 实验组1 | 实验组2 | 实验组3 | 对照组 | |
例数(n) | 36 | 36 | 36 | 36 | 36 | 36 | 36 | 36 |
愈合天数 | 7.8 | 7.2 | 6.5 | 12.4 | 15.2 | 15.1 | 13.7 | 20.3 |
愈合率% | 100 | 100 | 100 | 97.3 | 100 | 100 | 100 | 94.4 |
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