CN1723288A - 检测系统 - Google Patents

检测系统 Download PDF

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Publication number
CN1723288A
CN1723288A CNA2003801056004A CN200380105600A CN1723288A CN 1723288 A CN1723288 A CN 1723288A CN A2003801056004 A CNA2003801056004 A CN A2003801056004A CN 200380105600 A CN200380105600 A CN 200380105600A CN 1723288 A CN1723288 A CN 1723288A
Authority
CN
China
Prior art keywords
probe
dna duplex
sample
wedding agent
nucleic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2003801056004A
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English (en)
Chinese (zh)
Inventor
M·A·李
M·巴斯彻
T·布郎
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UK Secretary of State for Defence
Original Assignee
UK Secretary of State for Defence
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by UK Secretary of State for Defence filed Critical UK Secretary of State for Defence
Publication of CN1723288A publication Critical patent/CN1723288A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Eye Examination Apparatus (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Geophysics And Detection Of Objects (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
CNA2003801056004A 2002-10-10 2003-10-10 检测系统 Pending CN1723288A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0223563.8A GB0223563D0 (en) 2002-10-10 2002-10-10 Detection system
GB0223563.8 2002-10-10

Publications (1)

Publication Number Publication Date
CN1723288A true CN1723288A (zh) 2006-01-18

Family

ID=9945669

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2003801056004A Pending CN1723288A (zh) 2002-10-10 2003-10-10 检测系统

Country Status (10)

Country Link
US (1) US20060127906A1 (enExample)
EP (1) EP1554404B1 (enExample)
JP (1) JP2006501836A (enExample)
CN (1) CN1723288A (enExample)
AT (1) ATE429513T1 (enExample)
AU (1) AU2003274316A1 (enExample)
CA (1) CA2501636A1 (enExample)
DE (1) DE60327345D1 (enExample)
GB (1) GB0223563D0 (enExample)
WO (1) WO2004033726A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111247252A (zh) * 2017-08-18 2020-06-05 Lgc基因组学有限公司 用于检测核酸分子的方法和试剂盒
CN111562244A (zh) * 2020-05-25 2020-08-21 赣南师范大学 一种检测柔红霉素的稀土时间分辨荧光探针和试剂盒

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0112868D0 (en) * 2001-05-25 2001-07-18 Secr Defence Detection system
WO2005059548A1 (ja) 2003-12-19 2005-06-30 Kankyo Engineering Co., Ltd. 核酸測定用新規混合物、及びそれを用いる核酸の新規測定方法並びにそれらに用いる核酸プローブ
US20070072211A1 (en) 2005-06-30 2007-03-29 Roche Molecular Systems, Inc. Asymmetric PCR coupled with post-PCR characterization for the identification of nucleic acids
GB0603190D0 (en) * 2006-02-16 2006-03-29 Enigma Diagnostics Ltd Detection system
DK2004847T3 (en) 2006-03-16 2017-08-21 Pentabase Aps Oligonucleotides comprising signaling pairs and hydrophobic nucleotides, "stemless beacons", for detection of nucleic acids, methylation status and mutants of nucleic acids
JP2009044967A (ja) * 2007-08-14 2009-03-05 Sony Corp 二本鎖核酸の形成に係る情報を得る方法
US8658366B2 (en) 2008-09-18 2014-02-25 Roche Molecular Systems, Inc. Detection of target variants using a fluorescent label and a soluble quencher
GB201004339D0 (en) 2010-03-16 2010-04-28 Enigma Diagnostics Ltd Sequence detection assay
GB201007868D0 (en) 2010-05-11 2010-06-23 Enigma Diagnostics Ltd Sequence detection assay
EP2569447A4 (en) 2010-05-14 2013-11-27 Fluidigm Corp ASSAYS FOR THE DETECTION OF GENOTYPES, MUTATIONS OR ANEUPLOIDY
AU2013202808B2 (en) 2012-07-31 2014-11-13 Gen-Probe Incorporated System and method for performing multiplex thermal melt analysis
CN107002140A (zh) * 2014-09-26 2017-08-01 双孔人公司 通过合成探针的纳米孔隙探测的靶序列检测
US11486873B2 (en) 2016-03-31 2022-11-01 Ontera Inc. Multipore determination of fractional abundance of polynucleotide sequences in a sample
DE102019219531A1 (de) * 2019-12-13 2021-06-17 Robert Bosch Gmbh Verfahren zur Durchführung einer Amplifikationsreaktion in einer mikrofluidischen Vorrichtung

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1533151A (fr) * 1962-05-18 1968-07-19 Rhone Poulenc Sa Nouvel antibiotique et sa préparation
US4012284A (en) * 1962-11-16 1977-03-15 Societa' Farmaceutici Italia, S.p.A. Process of preparation of antibiotic F.I. 1762 derivatives
US3183157A (en) * 1963-02-01 1965-05-11 Upjohn Co Antibiotic nogalamycin and method of producing
US4197249A (en) * 1977-08-15 1980-04-08 American Cyanamid Company 1,4-Bis(substituted-amino)-5,8-dihydroxyanthraquinones and leuco bases thereof
US4469863A (en) * 1980-11-12 1984-09-04 Ts O Paul O P Nonionic nucleic acid alkyl and aryl phosphonates and processes for manufacture and use thereof
US5200313A (en) * 1983-08-05 1993-04-06 Miles Inc. Nucleic acid hybridization assay employing detectable anti-hybrid antibodies
US4868103A (en) * 1986-02-19 1989-09-19 Enzo Biochem, Inc. Analyte detection by means of energy transfer
US5208323A (en) * 1989-08-10 1993-05-04 Universite Laval Coupling of an anti-tumor to an antibody using glutaraldehyde preactivated anti-tumor agent
GB8923075D0 (en) * 1989-10-13 1989-11-29 Patterson Laurence H Anti-cancer compounds
US5994056A (en) * 1991-05-02 1999-11-30 Roche Molecular Systems, Inc. Homogeneous methods for nucleic acid amplification and detection
US5567583A (en) * 1991-12-16 1996-10-22 Biotronics Corporation Methods for reducing non-specific priming in DNA detection
AU689815B2 (en) * 1993-08-30 1998-04-09 Promega Corporation Nucleic acid purification compositions and methods
US5491063A (en) * 1994-09-01 1996-02-13 Hoffmann-La Roche Inc. Methods for in-solution quenching of fluorescently labeled oligonucleotide probes
DE69527125T2 (de) * 1994-11-09 2003-02-27 Hitachi, Ltd. Verfahren und Vorrichtung zur DNS Analyse
US5858397A (en) * 1995-10-11 1999-01-12 University Of British Columbia Liposomal formulations of mitoxantrone
EP2369007B1 (en) * 1996-05-29 2015-07-29 Cornell Research Foundation, Inc. Detection of nucleic acid sequence differences using coupled ligase detection and polymerase chain reactions
US6403311B1 (en) * 1997-02-12 2002-06-11 Us Genomics Methods of analyzing polymers using ordered label strategies
ATE273381T1 (de) * 1997-02-12 2004-08-15 Eugene Y Chan Verfahren zur analyse von polymeren
US6646149B1 (en) * 1997-07-15 2003-11-11 Nicolaas M. J. Vermeulin Polyamine analogues as therapeutic and diagnostic agents
GB9725197D0 (en) * 1997-11-29 1998-01-28 Secr Defence Detection system
KR100386606B1 (ko) * 2001-02-03 2003-06-02 엘지전자 주식회사 Ｄｎａ 검출 방법 및 그 장치
GB0112868D0 (en) * 2001-05-25 2001-07-18 Secr Defence Detection system
KR100459394B1 (ko) * 2001-10-30 2004-12-03 엘지전자 주식회사 인터컬레이터를 이용한 핵산의 전기화학발광 검출방법
AU2002351193A1 (en) * 2001-11-28 2003-06-10 Mj Bioworks Incorporated Parallel polymorphism scoring by amplification and error correction
CA2500129C (en) * 2002-09-30 2011-03-29 F. Hoffmann-La Roche Ag Oligonucleotides for genotyping thymidylate synthase gene
US7354706B2 (en) * 2003-09-09 2008-04-08 The Regents Of The University Of Colorado, A Body Corporate Use of photopolymerization for amplification and detection of a molecular recognition event
EP1694869A2 (en) * 2003-11-10 2006-08-30 Investigen, Inc. Methods of preparing nucleic acid for detection

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111247252A (zh) * 2017-08-18 2020-06-05 Lgc基因组学有限公司 用于检测核酸分子的方法和试剂盒
CN111562244A (zh) * 2020-05-25 2020-08-21 赣南师范大学 一种检测柔红霉素的稀土时间分辨荧光探针和试剂盒
CN111562244B (zh) * 2020-05-25 2023-02-07 赣南师范大学 一种检测柔红霉素的稀土时间分辨荧光探针和试剂盒

Also Published As

Publication number Publication date
JP2006501836A (ja) 2006-01-19
EP1554404A1 (en) 2005-07-20
ATE429513T1 (de) 2009-05-15
CA2501636A1 (en) 2004-04-22
US20060127906A1 (en) 2006-06-15
GB0223563D0 (en) 2002-11-20
AU2003274316A1 (en) 2004-05-04
EP1554404B1 (en) 2009-04-22
WO2004033726A1 (en) 2004-04-22
DE60327345D1 (de) 2009-06-04

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