CN1698779A - Toothache relieving oral cavity spray and its preparation method - Google Patents
Toothache relieving oral cavity spray and its preparation method Download PDFInfo
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- CN1698779A CN1698779A CN 200510072146 CN200510072146A CN1698779A CN 1698779 A CN1698779 A CN 1698779A CN 200510072146 CN200510072146 CN 200510072146 CN 200510072146 A CN200510072146 A CN 200510072146A CN 1698779 A CN1698779 A CN 1698779A
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Abstract
Disclosed is a toothache relieving oral cavity spray and its preparation method, the invention solves their problems of most of the market available medicament for treating toothache including, needing to be administered orally, strong side effect, slow action, and inconvenience in use.
Description
Technical field
The present invention relates to a kind of oral spray for the treatment of toothache and preparation method thereof, belong to the field of Chinese medicines.
Background technology
The toothache of indication of the present invention is many different common symptoms of having a toothache and causing.Violent tooth pain can cause headache again, otalgia, and the cervical region pain, influence is chewed and is worked.Chinese medicine thinks that this disease is with the wind heat stomach-fire, and the pain that dental caries etc. cause is the most common.Belong to wind heat, disease is seen swelling and aching of gum, and shapes such as dry thirsty, the constipation of halitosis belong to dental caries, and disease sees that when eating food such as hot and cold, sour, sweet feel tooth pain, degree of depth dental caries also can cause pulpitis etc.
Toothache is a kind of commonly encountered diseases, frequently-occurring disease.As the saying goes that " toothache is not a disease, and pain is got up and can be killed." though having a toothache is unlikely to threat to life, it is terribly really that pain is got up.The medicine that is used for the treatment of toothache in the market is oral analgesic mostly, side effect is big, it is slow to take effect, and still there be not more medicine evident in efficacy and a dosage form that is specifically designed to treatment and nursing toothache, thereby in treatment, brought great difficulty for the patient, cause numerous patients not treated timely and effectively and to nurse.
Summary of the invention
An object of the present invention is to provide a kind of oral spray for the treatment of toothache.
Another purpose of invention provides a kind of preparation method for the treatment of the oral spray of toothache.
For achieving the above object, a technical scheme of the present invention provides a kind of oral spray for the treatment of toothache, each material mass percentage composition is as follows in the oral spray of this treatment toothache: sodium lauryl sulfate 0.5-2%, glycerol 3-8%, Sorbitol 3-8%, xylitol 0.5-5%, glucide 0.5-1%, ethanol 8-12%, chloral hydrate 8-12%, pure water 5-10%, all the other are the Chinese medicine preparation extracting solution.
Can also comprise propylparaben alcoholic solution 0-0.2%, essence 0-0.2%.
Chinese medicine preparation extract recipe and consumption are by weight, and be as follows:
This prescription has 28 flavor Chinese medicines and forms: Herba Asari 40-60 part, Rhizoma Pinelliae 20-30 part, Rhizoma Arisaematis 20-30 part, Radix Saposhnikoviae 20-30 part, Radix Aconiti Kusnezoffii 15-25 part, sweetgum 15-25 part, Resina Populi Diversifoliae 20-30 part, Radix Angelicae Dahuricae 20-30 part, Herba Menthae 15-25 part, Radix Et Rhizoma Rhei 15-25 part, Borneolum Syntheticum 5-10 part, Flos Caryophylli 25-35 part, Rhizoma Chuanxiong 25-35 part, Fructus Cnidii 40-60 part, Semen Hyoscyami 15-25 part, Rhizoma Cimicifugae 10-20 part, Cortex Phellodendri 15-25 part, Rhizoma Anemarrhenae 15-25 part, Rhizoma Coptidis 10-20 part, Radix Ophiopogonis 25-35 part, Radix Paeoniae Rubra 25-35 part, Rhizoma Atractylodis Macrocephalae 25-35 part, Galla Chinensis 15-20 part, Fructus Xanthii 15-25 part, Herba Euphorbiae Helioscopiae 25-35 part, Rhizoma Kaempferiae 15-25 part, Radix Glycyrrhizae 10-20 part, Chinese liquor 5000-6000 part.
The optimization formula that the present invention treats the oral spray of toothache is: each substance weight percentage composition is as follows:
Chinese medicine preparation extracting solution 60%, sodium lauryl sulfate 1%, glycerol 5%, Sorbitol 5%, xylitol 2%, propylparaben alcoholic solution 0.1%, essence 0.1%, glucide 0.8%, ethanol 10%, chloral hydrate 10%, pure water 6%.
Preferred Chinese medicine preparation extract recipe and consumption
This prescription has 28 flavor Chinese medicines and forms: 50 parts of Herba Asaris, 25 parts of the Rhizoma Pinelliaes, 25 parts of Rhizoma Arisaematis, 25 parts of Radix Saposhnikoviaes, 20 parts of Radix Aconiti Kusnezoffii, 20 parts of sweetgums, 25 parts of Resina Populi Diversifoliaes, 25 parts of the Radixs Angelicae Dahuricae, 20 parts of Herba Menthaes, 20 parts of Radix Et Rhizoma Rhei, 6 parts of Borneolum Syntheticums, 30 parts of Flos Caryophyllis, 30 parts of Rhizoma Chuanxiongs, 50 parts of Fructus Cnidiis, 20 parts of Semen Hyoscyamis, 15 parts of Rhizoma Cimicifugaes, 20 parts of Cortex Phellodendris, 20 parts of the Rhizoma Anemarrhenaes, 15 parts of Rhizoma Coptidis, 30 parts of Radix Ophiopogonis, 30 parts of Radix Paeoniae Rubra, 30 parts of the Rhizoma Atractylodis Macrocephalaes, 18 parts of Galla Chinensiss, 20 parts of Fructus Xanthii, 30 parts of Herba Euphorbiae Helioscopiae, 20 parts of Rhizoma Kaempferiae, 15 parts in Radix Glycyrrhizae, 5000 parts of Chinese liquor.
The present invention treats the preparation method of the oral spray of toothache:
1. the manufacture method of Chinese medicine preparation extracting solution.
Chinese herbal medicine is put in the clean container, adds Chinese liquor 2500ml, carry out just soaking extraction, after soaking 15 days, filter, in filtering residue, add remaining Chinese liquor, soak extraction again, 15 days after-filtration with cold the following the example of of merceration.In the medicinal residues after the extraction, add 5000 parts by weight of purified water, boil and fry in shallow oil 15 minutes after-filtration, the yeast for brewing rice wine liquid that decocting juice is also just soaked again extraction mixes, and it is standby to stir,
2. treat the manufacture method of the oral spray of toothache:
(1) the Chinese medicine preparation extracting solution is put into rustless steel container, sodium lauryl sulfate, Radix Glycyrrhizae, Sorbitol, xylitol are put into it successively, through fully stirring, after making it to dissolve fully, standby.
(2) with water chloro aldehyde, essence, glucide, put into successively in the solution that step 1 makes, after fully stirring, add ethanol, propylparaben alcoholic solution and pure water, restir left standstill 24 hours after 30 minutes, stock solution.
In packing or when using, with stock solution with pure water in 1: after the ratio of 2-3 is diluted, can use, only need be aimed at the pain tooth with this product and spray gently or get this product 30-50ml oral cavity rinsing the mouth more than 3 minutes, spue with saliva then, can reach analgesic effect.
Last toothache nebulization, following toothache is with the method for gargling.
The invention is characterized in that Chinese medicine preparation itself has clearing away heat and cooling blood, pathogenic fire purging dampness, dispel the wind detumescence, sterilization pain relieving this effect, chemicals has the effect of the seasoning of preserving moisture sterilization pain relieving, and the two combination has reached easy to use, administration puts in place, easy operating, purpose evident in efficacy can be removed the hardship of patient's pain rapidly.
Composition and effect below in conjunction with each raw material among the present invention further specify beneficial effect of the present invention:
Herba Asari: have another name called Xiao Xin, Kingdonia uniflora, Jin Pencao, recluse's ginseng; Whole herb with root for aristolochiaceae plant Herba Asari or magnificent Herba Asari; Nature and flavor: suffering, temperature; Function cures mainly: expelling wind and cold, row water is had one's ideas straightened out.
The Rhizoma Pinelliae: have another name called ground literary composition, water beautiful, keep the field, show aunt, Sedum spectabile Boreau, old Fructus Colocasiae Esculentae, Fructus Crotonis, crow are first-class is the tuber of the aroid Rhizoma Pinelliae; Nature and flavor: hot, temperature, poisonous; Function cures mainly: drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass;
Rhizoma Arisaematis: be the fresh tuber of aroid Rhizoma Arisaematis, arisaema amurense Maxim or Arisaema heterophyllum B1. etc.Nature and flavor: toil, temperature, poisonous.Function cures mainly: drying dampness to eliminate phlegm, expelling wind for relieving convulsion, dispersing swelling and dissipating binds.
Radix Saposhnikoviae: be the root of umbelliferae Saposhnikovia divaricata.Nature and flavor: Xin Gan, temperature.Function cures mainly: deliver, dispel the wind, win and wet, pain relieving.
Radix Aconiti Kusnezoffii: have another name called Radix Aconiti Kusnezoffii, violet, Odontobutis obscura (T. Et S.), Gelsemium elegans Benth..Tuber for cohosh Aconitum carmichjaelii Debx., Aconitum kusnezoffii Reichb or other multiple congeners; Nature and flavor: suffering, heat, poisonous.Function cures mainly: search wind prevailing over dampness, dispersing cold for relieving pain is opened expectorant, detumescence.
Sweetgum: be Hamamelidaceae plant sweetgum; Nature and flavor: arduous, flat, slightly poisonous; Function cures mainly: control diseases such as acute gastroenteritis, dysentery, puerperal exposure to wind, paralysis, swelling due to wind;
Resina Populi Diversifoliae: different name: poon rule, stone rule, stone tear, poon alkali; Be the resin of Salicaceae plant Populus euphratica, in soil, retain and form for many years; Nature and flavor: salty in the mouth hardship, Great Cold, nontoxic; Function cures mainly: heat clearing away, reduce phlegm, softening the hard mass.
The Radix Angelicae Dahuricae: different name fragrance, Ze Fen, Radix Angelicae Dahuricae (Radix Heraclei Scabridi); Root for the samphire Xingan Radix Angelicae Dahuricae, angelica anomala, Radix angelicae dahuricae or Yunnan cattle Radix Saposhnikoviae; Nature and flavor: hot, warm; Function cures mainly: dispel the wind dampness, detumescence, pain relieving.
Herba Menthae: have another name called breath flower at night, luxuriant lotus dish etc. are herb or the leaf of labiate Herba Menthae or tame Herba Menthae; Nature and flavor: suffering, cold; Function cures mainly: dispelling wind, dispel the heat, ward off dirty, the detoxifcation.
Radix Et Rhizoma Rhei: different name: yellow good, fire ginseng, skin are as, general, Radix Et Rhizoma Rhei; Be polygonum rheum palmatum, Rheum tanguticum or Rheum officinale rhizome; Nature and flavor: bitter, cold; Function cures mainly: the poison that purges heat, removing mass stagnate clots absorbing blood.
Borneolum Syntheticum: have another name called: Borneolum Syntheticum, borneol, Borneolum Syntheticum, sheet brain, etc., be the processed goods of Dipterocarpaceae plant Borneolum Syntheticum resin, or for Camphora, Lignum Pini Nodi wet goods with the synthetic product of being processed into of chemical method; Nature and flavor: arduous, cold.Function cures mainly: logical all keys, the stagnated fire of loosing, removing nebula make eye bright, reducing swelling and alleviating pain.
Flos Caryophylli: different name: clove tree, dismemberent perfume, male Flos Caryophylli etc.; Alabastrum for plant clove of myrtaceae; Nature and flavor: hot, warm; Function cures mainly: warming middle-JIAO, warming the kidney, sending down the abnormal ascending QI.
Rhizoma Chuanxiong: samphire Rhizoma Chuanxiong rhizome.Nature and flavor: suffering, temperature.Function cures mainly activating QI to alleviate the depression dispeiling pathogenic wind and removing dampness, promoting blood circulation and stopping pain.
Fructus Cnidii: different name: Serpentis rice, Serpentis pearl, gas fruit, Radix Habenariae Dentatae, wild Fructus Foeniculi; Fruit for the samphire cnidium monnieri; Nature and flavor: arduous, warm; Function cures mainly: warming the kidney to activate YANG, dispel the wind, dampness, parasite killing.
Semen Hyoscyami: have another name called hyoscyami, SEMEN HYOSCYAMI, little Semen daturae, smoked serratd edge; Seed for the plant of Solanaceae hyoscyami; Nature and flavor: toil, temperature, poisonous; Function cures mainly: decide the epilepsy pain relieving.
Cortex Phellodendri: function: clearing away damp-heat, separate sore; Cure mainly: carbuncle skin infection, eczema pruritus, leukorrhagia pyretic stranguria etc.Main Ingredients and Appearance: contain XIAONIE alkali, obacunone, Cortex Phellodendri lactone, dictamnolactone.Pharmacological action: antibiotic, antifungal, convergence antiinflammatory.
The Rhizoma Anemarrhenae: have another name called: connect mother, DISHEN, water ginseng, women thunder, youngster's grass Dioscorea nipponica Mak. Ningpo Yam Rhizome etc., be the root of the liliaceous plant Rhizoma Anemarrhenae; Nature and flavor: bitter, cold; Function cures mainly: nourishing YIN to lower pathogenic fire, moisturize laxation.
Rhizoma Coptidis: having another name called flavor companys, Wang Lian, Zhi Lian, is a kind of in the Rhizoma Coptidis, and main product is in Sichuan, nature and flavor: hardship, to tremble with fear, and function cures mainly: pathogenic fire purging, dampness, detoxifcation parasite killing.
Radix Ophiopogonis: have another name called Radix Ophiopogonis, be the careless tuber of liliaceous plant along the street; Nature and flavor: sweet little hardship, cold; Function cures mainly: the nourishing YIN and moistening the lung relieving restlessness that clears away heart-fire, reinforcing stomach reg fluid.
Radix Paeoniae Rubra: it is flat to have another name called wooden Radix Paeoniae, red Radix Paeoniae, Radix clerodendri bungei; Root for cohosh Radix Paeoniae, wild Radix Paeoniae, CHUANSHAO medicine; Nature and flavor: bitter, cool; Function cures mainly: clots absorbing, pain relieving, removing heat from blood, detumescence.
The Rhizoma Atractylodis Macrocephalae: have another name called Folium seu Radix Clausenae dentatae, Ovum Gallus domesticus Flavus, be the root or the root bark of rutaceae bassoon; Nature and flavor, bitter sweet, warm; Function cures mainly: spleen reinforcing, stomach reinforcing, dampness and in
Galla Chinensis: different name Conch Meretricis seu Cyclinae, hundred worm storehouses, be the insect gall that times Aphidiadae insecticide Chinese Nut-gall aphid or melaphis peitan Tsai et Tang form on its host's Fructus rhois chinensis etc., function cures mainly: astringe the lung, astringing intestine to stop diarrhea, hemostasis detoxifcation.
Fructus Xanthii: have another name called grey son, Herba Xanthii is real, is the fruit of the band involucre of feverfew Herba Xanthii, and function cures mainly: wind, pain relieving, damp eliminating, parasite killing loose.
Herba Euphorbiae Helioscopiae: have another name called five phoenixes grass, RADIX EUPHORBIAE PEKINENSIS, careless eye; Herb for the euphorbia plant Herba Euphorbiae Helioscopiae; Function cures mainly: row water, expectorant, parasite killing, detoxifcation.
Rhizoma Kaempferiae: have another name called husky Rhizoma Zingiberis Recens, three rely, and are zingiberaceous plant Rhizoma Kaempferiae rhizome, and function cures mainly: warming middle-JIAO, help digestion, pain relieving.
Radix Glycyrrhizae, different name: MEICAO, sweet sweet; Base is former: be the root and the root stock of glycyrrhizic legume; Composition: root of Radix Glycyrrhizae and rhizome contain the triterpenoid saponin glycyrrhizic acid, biosone, 18 α-enoxolone and multiple flavone component comprise glycyrrhizin, isoliquiritigenin, liquiritin, neoliquriitin, neoisoliquiritin, isoliquiritigenin-4-β-glucose-β-curly garden parsley glucoside; Nature and flavor: sweet, flat; Function cures mainly: and middle emergency, lung moistening, detoxifcation, coordinating the actions of various ingredients in a prescription.
The present invention is guidance with motherland's Chinese medical theory, on the basis of traditional secret recipe, proved recipe, in conjunction with doctor trained in Western medicine chemical race and modern science and technology method, fundamentally improve treatment and nursing efficacy to toothache, remove the many difficulty of patient in therapeutic process, thereby reach easy to use, administration puts in place, easy operating is removed patient suffering's purpose as early as possible.
The invention is characterized in that Chinese medicine preparation itself has clearing away heat and cooling blood, pathogenic fire purging dampness, the detumescence of dispeling the wind, this effect of sterilization pain relieving.Chinese medicine preparation is made up of 28 flavors altogether, wherein, has Radix Paeoniae Rubra, Radix Et Rhizoma Rhei, Rhizoma Cimicifugae, Radix Ophiopogonis the effect of clearing away heat and cooling blood, Cortex Phellodendri, the Rhizoma Anemarrhenae, Rhizoma Coptidis etc., has the effect of rushing down dampness, the Rhizoma Pinelliae, Rhizoma Arisaematis, Galla Chinensis, Herba Asari, the Radix Angelicae Dahuricae etc. have the function of the detumescence of dispeling the wind, and Flos Caryophylli, Rhizoma Kaempferiae, Fructus Cnidii etc. have the effect of sterilization pain relieving.All medicines cooperate, play clearing away heat and cooling blood, pathogenic fire purging dampness altogether, the detumescence of dispeling the wind, the sterilization pain relieving effect, the chemical products chloral hydrate that in addition has analgesic activity, with the Radix Glycyrrhizae with the seasoning antisepsis of preserving moisture, Sorbitol, propylparaben alcoholic solution etc., make the present invention reach easy to use, administration puts in place, easy operating, purpose evident in efficacy.
Lee, upper left seven depth of threat degree dental caries, concurrent pulpitis, whole left face swelling, pain unbearably, but its hypertension, heart disease is arranged, and the dentist dare not handle easily, and spray is treated the oral spray of toothache after 3 minutes with the present invention, pain has alleviation slightly, after 5 minutes, and pain relief, adhere to using the present invention to treat the oral spray of toothache after one week, the disappearance of swelling and ache, after two weeks, the dental pulp inflammation disappears.
The Wang, toothache due to pathogenic wind-heat, the oral spray that spray is treated toothache with the present invention be after 3 minutes, and pain relief adheres to that the oral spray that uses the present invention to treat toothache gargles, and takes place without any disease in the oral cavity so far.
The specific embodiment:
Enumerate embodiment below, the present invention is further specified, but the present invention is not only limited to these embodiment.
Embodiment 1
In the oral spray of treatment toothache, the preparation of Chinese medicine preparation extracting solution: accurately take by weighing Herba Asari 50kg, Rhizoma Pinelliae 25kg, Rhizoma Arisaematis 25kg, Radix Saposhnikoviae 25kg, Radix Aconiti Kusnezoffii 20kg, sweetgum 20kg, Resina Populi Diversifoliae 25kg, Radix Angelicae Dahuricae 25kg, Herba Menthae 20kg, Radix Et Rhizoma Rhei 20kg, Borneolum Syntheticum 6kg, Flos Caryophylli 30kg, Rhizoma Chuanxiong 30kg, Fructus Cnidii 50kg, Semen Hyoscyami 20kg, Rhizoma Cimicifugae 15kg, Cortex Phellodendri 20kg, Rhizoma Anemarrhenae 20kg, Rhizoma Coptidis 15kg, Radix Ophiopogonis 30kg, Radix Paeoniae Rubra 30kg, Rhizoma Atractylodis Macrocephalae 30kg, Galla Chinensis 18kg, Fructus Xanthii 20kg, Herba Euphorbiae Helioscopiae 30kg, Rhizoma Kaempferiae 20kg, Radix Glycyrrhizae 15kg, Chinese liquor 5000kg.
Chinese herbal medicine is put in the clean container, adds Chinese liquor 2500ml, carry out just soaking extraction, after soaking 15 days, filter, in filtering residue, add remaining Chinese liquor, soak extraction again, 15 days after-filtration with cold the following the example of of merceration.With the medicinal residues after the extraction, add the 5000kg pure water, boil and fry in shallow oil 15 minutes after-filtration, the yeast for brewing rice wine liquid that decocting juice is also just soaked again extraction mixes, and it is standby to stir,
Embodiment 2
The preparation method of the oral spray of treatment toothache:
(1) accurately takes by weighing Chinese medicine preparation extracting solution 60kg, sodium lauryl sulfate 1kg, glycerol 5kg, Sorbitol 5kg, xylitol 2kg, propylparaben alcoholic solution 0.1kg, essence 0.1kg, glucide 0.8kg, ethanol 10kg, chloral hydrate 10kg, pure water 6kg.The Chinese medicine preparation extracting solution is put into rustless steel container, sodium lauryl sulfate, Radix Glycyrrhizae, Sorbitol, xylitol are put into it successively, through fully stirring, after making it to dissolve fully, standby.
(2) with water chloro aldehyde, essence, glucide, put into successively in the solution that step 1 makes, after fully stirring, add propylparaben alcoholic solution and pure water, restir left standstill 24 hours after 30 minutes, stock solution.
Embodiment 3-7
With the oral spray that the 1 same method preparation treatment with embodiment is had a toothache, concrete material name and proportioning that embodiment 3-7 uses are as shown in table 1.
Table 1:
| Material name | Embodiment 3 | Embodiment 4 | Embodiment 5 | Embodiment 6 | Embodiment 7 |
| Sodium lauryl sulfate | 0.5 | ?2 | ?0.8 | ?1.5 | ?1.2 |
| Glycerol | 3 | ?8 | ?5 | ?6 | ?4 |
| Sorbitol | 3 | ?8 | ?7 | ?4 | ?6 |
| Xylitol | 0.5 | ?5 | ?1 | ?2 | ?3 |
| The propylparaben alcoholic solution | 0 | ?0.2 | ?0.1 | ?0 | ?0.2 |
| Essence | 0 | ?0.2 | ?0.1 | ?0 | ?0.2 |
| Glucide | 0.5 | ?1 | ?0.6 | ?0.8 | ?0.6 |
| Ethanol | 8 | ?12 | ?9 | ?10 | ?11 |
| Chloral hydrate | 12 | ?8 | ?11 | ?9 | ?10 |
| Pure water | 10 | ?5 | ?6 | ?7 | ?8 |
| The Chinese medicine preparation extracting solution | 62.5 | ?50.6 | ?59.4 | ?59.7 | ?55.8 |
Embodiment 8-12
With the oral spray that the 2 same method preparation treatments with embodiment are had a toothache, concrete material name and proportioning that embodiment 8-12 uses are as shown in table 2.
Table 2:
| Material name | Embodiment 8 | Embodiment 9 | Embodiment 10 | Embodiment 11 | Embodiment 12 |
| Herba Asari | 40 | ?60 | ?55 | ?50 | ?45 |
| The Rhizoma Pinelliae | 20 | ?30 | ?25 | ?22 | ?28 |
| Rhizoma Arisaematis | 20 | ?30 | ?28 | ?26 | ?23 |
| Radix Saposhnikoviae | 20 | ?30 | ?21 | ?29 | ?27 |
| Radix Aconiti Kusnezoffii | 15 | ?25 | ?18 | ?20 | ?22 |
| Sweetgum | 15 | ?25 | ?20 | ?22 | ?18 |
| Resina Populi Diversifoliae | 20 | ?30 | ?25 | ?22 | ?28 |
| The Radix Angelicae Dahuricae | 20 | ?30 | ?28 | ?26 | ?23 |
| Herba Menthae | 15 | ?25 | ?18 | ?20 | ?22 |
| Radix Et Rhizoma Rhei | 15 | ?25 | ?20 | ?22 | ?18 |
| Borneolum Syntheticum | 5 | ?10 | ?6 | ?8 | ?9 |
| Flos Caryophylli | 25 | ?35 | ?28 | ?30 | ?32 |
| Rhizoma Chuanxiong | 25 | ?35 | ?28 | ?33 | ?30 |
| Fructus Cnidii | 40 | ?60 | ?55 | ?50 | ?45 |
| Semen Hyoscyami | 15 | ?25 | ?22 | ?18 | ?20 |
| Rhizoma Cimicifugae | 10 | ?20 | ?12 | ?14 | ?16 |
| Cortex Phellodendri | 15 | ?25 | ?18 | ?20 | ?22 |
| The Rhizoma Anemarrhenae | 15 | ?25 | ?20 | ?22 | ?18 |
| Rhizoma Coptidis | 10 | ?20 | ?12 | ?14 | ?16 |
| Radix Ophiopogonis | 25 | ?35 | ?28 | ?30 | ?32 |
| Radix Paeoniae Rubra | 25 | ?35 | ?28 | ?33 | ?30 |
| The Rhizoma Atractylodis Macrocephalae | 25 | ?35 | ?34 | ?31 | ?27 |
| Galla Chinensis | 15 | ?20 | ?16 | ?18 | ?17 |
| Fructus Xanthii | 15 | ?25 | ?13 | ?20 | ?16 |
| Herba Euphorbiae Helioscopiae | 25 | ?35 | ?34 | ?31 | ?27 |
| Rhizoma Kaempferiae | 15 | ?25 | ?20 | ?22 | ?18 |
| Radix Glycyrrhizae | 10 | ?20 | ?12 | ?18 | ?16 |
| Chinese liquor | 5000 | ?6000 | ?5500 | ?5800 | ?5200 |
Claims (7)
1. oral spray for the treatment of toothache, each substance weight percentage composition is as follows in the oral spray of this treatment toothache: sodium lauryl sulfate 0.5-2%, glycerol 3-8%, Sorbitol 3-8%, xylitol 0.5-5%, glucide 0.5-1%, ethanol 8-12%, chloral hydrate 8-12%, pure water 5-10%, all the other are the Chinese medicine preparation extracting solution.
2. the oral spray of treatment toothache according to claim 1 is characterized in that, can also comprise propylparaben alcoholic solution 0-0.2%, essence 0-0.2%.
3. the oral spray of treatment toothache according to claim 1 is characterized in that each material mass percentage composition is as follows: sodium lauryl sulfate 1%, glycerol 5%, Sorbitol 5%, xylitol 2%, propylparaben alcoholic solution 0.1%, essence 0.1%, glucide 0.8%, ethanol 10%, chloral hydrate 10%, pure water 6%, Chinese medicine preparation extracting solution 60%.
4. the oral spray of treatment toothache according to claim 1, it is characterized in that Chinese medicine preparation extract recipe and consumption: Herba Asari 40-60 part, Rhizoma Pinelliae 20-30 part, Rhizoma Arisaematis 20-30 part, Radix Saposhnikoviae 20-30 part, Radix Aconiti Kusnezoffii 15-25 part, sweetgum 15-25 part, Resina Populi Diversifoliae 20-30 part, Radix Angelicae Dahuricae 20-30 part, Herba Menthae 15-25 part, Radix Et Rhizoma Rhei 15-25 part, Borneolum Syntheticum 5-10 part, Flos Caryophylli 25-35 part, Rhizoma Chuanxiong 25-35 part, Fructus Cnidii 40-60 part, Semen Hyoscyami 15-25 part, Rhizoma Cimicifugae 10-20 part, Cortex Phellodendri 15-25 part, Rhizoma Anemarrhenae 15-25 part, Rhizoma Coptidis 10-20 part, Radix Ophiopogonis 25-35 part, Radix Paeoniae Rubra 25-35 part, Rhizoma Atractylodis Macrocephalae 25-35 part, Galla Chinensis 15-20 part, Fructus Xanthii 15-25 part, Herba Euphorbiae Helioscopiae 25-35 part, Rhizoma Kaempferiae 15-25 part, Radix Glycyrrhizae 10-20 part, Chinese liquor 5000-6000 part.
5. the oral spray of treatment toothache according to claim 1, it is characterized in that, Chinese medicine preparation extract recipe and consumption by weight: 50 parts of Herba Asaris, 25 parts of the Rhizoma Pinelliaes, 25 parts of Rhizoma Arisaematis, 25 parts of Radix Saposhnikoviaes, 20 parts of Radix Aconiti Kusnezoffii, 20 parts of sweetgums, 25 parts of Resina Populi Diversifoliaes, 25 parts of the Radixs Angelicae Dahuricae, 20 parts of Herba Menthaes, 20 parts of Radix Et Rhizoma Rhei, 6 parts of Borneolum Syntheticums, 30 parts of Flos Caryophyllis, 30 parts of Rhizoma Chuanxiongs, 50 parts of Fructus Cnidiis, 20 parts of Semen Hyoscyamis, 15 parts of Rhizoma Cimicifugaes, 20 parts of Cortex Phellodendris, 20 parts of the Rhizoma Anemarrhenaes, 15 parts of Rhizoma Coptidis, 30 parts of Radix Ophiopogonis, 30 parts of Radix Paeoniae Rubra, 30 parts of the Rhizoma Atractylodis Macrocephalaes, 18 parts of Galla Chinensiss, 20 parts of Fructus Xanthii, 30 parts of Herba Euphorbiae Helioscopiae, 20 parts of Rhizoma Kaempferiae, 15 parts in Radix Glycyrrhizae, 5000 parts of Chinese liquor.
6. method for preparing the oral spray of the described treatment of claim 1 toothache, this method may further comprise the steps:
(1) the Chinese medicine preparation extracting solution is put into rustless steel container, sodium lauryl sulfate, glycerol, Sorbitol, xylitol are put into it successively, through fully stirring, after making it to dissolve fully, standby;
(2) with water chloro aldehyde, essence, glucide, put into successively in the solution that step 1 makes, after fully stirring, add ethanol, propylparaben alcoholic solution and pure water, restir left standstill 24 hours after 30 minutes, stock solution.
7. the preparation method of the oral spray of treatment toothache according to claim 6, it is characterized in that: the preparation method of Chinese medicine preparation extracting solution wherein is put in Chinese herbal medicine in the clean container, add Chinese liquor 2500ml, carry out just soaking extraction, after soaking 15 days, filter, in filtering residue, add remaining Chinese liquor, soak extraction again, 15 days after-filtration; In the medicinal residues after extraction, add 5000 parts by weight of purified water, boil and fry in shallow oil 15 minutes after-filtration, filtrate and the first yeast for brewing rice wine liquid that soaks extraction are again mixed, stir.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200510072146 CN1698779A (en) | 2005-05-25 | 2005-05-25 | Toothache relieving oral cavity spray and its preparation method |
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Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101947198A (en) * | 2010-09-10 | 2011-01-19 | 甘肃奇正藏药有限公司 | Toothpaste special for pregnant women and preparation process thereof |
| CN101416926B (en) * | 2008-11-21 | 2011-03-16 | 福建福泽医药器械科技有限公司 | Grapefruit mouth spraying agent and preparation method thereof |
| CN102579805A (en) * | 2012-03-23 | 2012-07-18 | 吕海秀 | Mouthwash for treating orthodontic gingivitis |
| CN102885969A (en) * | 2011-09-13 | 2013-01-23 | 徐柔云 | Externally applied cream for treating toothache caused by deficiency fire |
| CN102961728A (en) * | 2012-12-06 | 2013-03-13 | 王辉 | Medicament for preventing and treating children saprodontia |
| CN103505555A (en) * | 2012-06-21 | 2014-01-15 | 黄承金 | Method for treating toothache |
| CN103830679A (en) * | 2014-03-17 | 2014-06-04 | 来维营 | Medicine for treating irritable bowel syndrome and applications thereof |
| CN104825779A (en) * | 2015-04-23 | 2015-08-12 | 刘德臻 | Traditional Chinese medicine oral aerosol |
| CN104906348A (en) * | 2015-06-11 | 2015-09-16 | 王淑霞 | Traditional Chinese medicine oral aerosol |
| WO2016169125A1 (en) * | 2015-04-22 | 2016-10-27 | 深圳市共创百业科技开发有限公司 | Traditional chinese medicine composition for treating odontalgia under o2o offline conditioning and preparation method therefor |
| CN109464540A (en) * | 2018-12-21 | 2019-03-15 | 广东方制药有限公司 | A kind of alleviation oral cavity and the spray of throat discomfort and preparation method thereof |
| CN109758403A (en) * | 2019-03-29 | 2019-05-17 | 上海涵博生物科技有限公司 | One kind is quick-acting to control toothache by spraying |
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Cited By (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101416926B (en) * | 2008-11-21 | 2011-03-16 | 福建福泽医药器械科技有限公司 | Grapefruit mouth spraying agent and preparation method thereof |
| CN101947198A (en) * | 2010-09-10 | 2011-01-19 | 甘肃奇正藏药有限公司 | Toothpaste special for pregnant women and preparation process thereof |
| CN101947198B (en) * | 2010-09-10 | 2013-09-11 | 甘肃奇正藏药有限公司 | Toothpaste special for pregnant women and preparation process thereof |
| CN102885969A (en) * | 2011-09-13 | 2013-01-23 | 徐柔云 | Externally applied cream for treating toothache caused by deficiency fire |
| CN102885969B (en) * | 2011-09-13 | 2014-03-12 | 庄章彬 | Externally applied cream for treating toothache caused by deficiency fire |
| CN102579805A (en) * | 2012-03-23 | 2012-07-18 | 吕海秀 | Mouthwash for treating orthodontic gingivitis |
| CN102579805B (en) * | 2012-03-23 | 2013-07-10 | 吕海秀 | Mouthwash for treating orthodontic gingivitis |
| CN103505555A (en) * | 2012-06-21 | 2014-01-15 | 黄承金 | Method for treating toothache |
| CN102961728B (en) * | 2012-12-06 | 2014-02-19 | 王辉 | Medicament for preventing and treating children saprodontia |
| CN102961728A (en) * | 2012-12-06 | 2013-03-13 | 王辉 | Medicament for preventing and treating children saprodontia |
| CN103830679A (en) * | 2014-03-17 | 2014-06-04 | 来维营 | Medicine for treating irritable bowel syndrome and applications thereof |
| WO2016169125A1 (en) * | 2015-04-22 | 2016-10-27 | 深圳市共创百业科技开发有限公司 | Traditional chinese medicine composition for treating odontalgia under o2o offline conditioning and preparation method therefor |
| CN104825779A (en) * | 2015-04-23 | 2015-08-12 | 刘德臻 | Traditional Chinese medicine oral aerosol |
| CN104906348A (en) * | 2015-06-11 | 2015-09-16 | 王淑霞 | Traditional Chinese medicine oral aerosol |
| CN109464540A (en) * | 2018-12-21 | 2019-03-15 | 广东方制药有限公司 | A kind of alleviation oral cavity and the spray of throat discomfort and preparation method thereof |
| CN109464540B (en) * | 2018-12-21 | 2021-05-07 | 广东一方制药有限公司 | Spray for relieving discomfort of oral cavity and throat and preparation method thereof |
| CN109758403A (en) * | 2019-03-29 | 2019-05-17 | 上海涵博生物科技有限公司 | One kind is quick-acting to control toothache by spraying |
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