CN1694705A - 用作依赖细胞周期蛋白激酶抑制剂的吡唑并嘧啶 - Google Patents

用作依赖细胞周期蛋白激酶抑制剂的吡唑并嘧啶 Download PDF

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Publication number
CN1694705A
CN1694705A CNA038249081A CN03824908A CN1694705A CN 1694705 A CN1694705 A CN 1694705A CN A038249081 A CNA038249081 A CN A038249081A CN 03824908 A CN03824908 A CN 03824908A CN 1694705 A CN1694705 A CN 1694705A
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China
Prior art keywords
alkyl
aryl
heteroaryl
chemical compound
cycloalkyl
Prior art date
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Pending
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CNA038249081A
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English (en)
Chinese (zh)
Inventor
T·J·古兹
K·普拉奇
M·P·多怀尔
R·J·多尔
V·M·吉拉加威拉汉
C·肯特森
B·麦克基崔克
L·W·迪拉德
V·D·崔恩
希建明
R·A·詹姆斯
朴涵宋
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacopeia Drug Discovery Inc
Merck Sharp and Dohme LLC
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Pharmacopeia Drug Discovery Inc
Schering Corp
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Application filed by Pharmacopeia Drug Discovery Inc, Schering Corp filed Critical Pharmacopeia Drug Discovery Inc
Publication of CN1694705A publication Critical patent/CN1694705A/zh
Pending legal-status Critical Current

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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
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  • Chemical Kinetics & Catalysis (AREA)
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  • Pharmacology & Pharmacy (AREA)
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  • Neurology (AREA)
  • Neurosurgery (AREA)
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  • Biomedical Technology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
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  • Pulmonology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
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  • Ophthalmology & Optometry (AREA)
  • Transplantation (AREA)
  • Psychiatry (AREA)
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CNA038249081A 2002-09-04 2003-09-03 用作依赖细胞周期蛋白激酶抑制剂的吡唑并嘧啶 Pending CN1694705A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40818202P 2002-09-04 2002-09-04
US60/408,182 2003-09-04

Publications (1)

Publication Number Publication Date
CN1694705A true CN1694705A (zh) 2005-11-09

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CNA038249081A Pending CN1694705A (zh) 2002-09-04 2003-09-03 用作依赖细胞周期蛋白激酶抑制剂的吡唑并嘧啶

Country Status (14)

Country Link
US (2) US7084271B2 (enExample)
EP (1) EP1545533A1 (enExample)
JP (2) JP2006500391A (enExample)
KR (1) KR20050057072A (enExample)
CN (1) CN1694705A (enExample)
AR (1) AR041135A1 (enExample)
AU (1) AU2003265901B2 (enExample)
CA (1) CA2497539A1 (enExample)
MX (1) MXPA05002574A (enExample)
NZ (1) NZ539163A (enExample)
PE (1) PE20040998A1 (enExample)
TW (1) TW200412966A (enExample)
WO (1) WO2004022062A1 (enExample)
ZA (1) ZA200501854B (enExample)

Cited By (2)

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Publication number Priority date Publication date Assignee Title
CN106170489A (zh) * 2014-05-28 2016-11-30 诺华股份有限公司 新的吡唑并嘧啶衍生物及其作为malt1抑制剂的用途
CN113248500A (zh) * 2021-06-10 2021-08-13 中国药科大学 氮杂吲哚嘧啶胺杂环化合物及其制备方法和应用

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CN106170489A (zh) * 2014-05-28 2016-11-30 诺华股份有限公司 新的吡唑并嘧啶衍生物及其作为malt1抑制剂的用途
CN106170489B (zh) * 2014-05-28 2019-05-03 诺华股份有限公司 新的吡唑并嘧啶衍生物及其作为malt1抑制剂的用途
CN113248500A (zh) * 2021-06-10 2021-08-13 中国药科大学 氮杂吲哚嘧啶胺杂环化合物及其制备方法和应用
WO2022257568A1 (zh) * 2021-06-10 2022-12-15 中国药科大学 氮杂吲哚嘧啶胺杂环化合物及其制备方法和应用

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US20060173017A1 (en) 2006-08-03
US7468372B2 (en) 2008-12-23
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