CN1649610A - 一种用于加强温血动物的免疫、抗炎、抗肿瘤以及 d n a修复过程的植物水溶性提取物生物活性组分的分离纯化以及结构鉴定 - Google Patents

一种用于加强温血动物的免疫、抗炎、抗肿瘤以及 d n a修复过程的植物水溶性提取物生物活性组分的分离纯化以及结构鉴定 Download PDF

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Publication number
CN1649610A
CN1649610A CNA038101599A CN03810159A CN1649610A CN 1649610 A CN1649610 A CN 1649610A CN A038101599 A CNA038101599 A CN A038101599A CN 03810159 A CN03810159 A CN 03810159A CN 1649610 A CN1649610 A CN 1649610A
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CN
China
Prior art keywords
extract
mammal
biologically active
quinic acid
med
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Pending
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CNA038101599A
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English (en)
Chinese (zh)
Inventor
罗纳德·W·佩罗
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Individual
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Individual
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27788020&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN1649610(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Individual filed Critical Individual
Publication of CN1649610A publication Critical patent/CN1649610A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/74—Rubiaceae (Madder family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
CNA038101599A 2002-03-07 2003-03-07 一种用于加强温血动物的免疫、抗炎、抗肿瘤以及 d n a修复过程的植物水溶性提取物生物活性组分的分离纯化以及结构鉴定 Pending CN1649610A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/093,794 2002-03-07
US10/093,794 US6964784B2 (en) 2002-03-07 2002-03-07 Method of preparation and composition of a water soluble extract of the bioactive component of the plant species uncaria for enhancing immune, anti-inflammatory, anti-tumor and dna repair processes of warm blooded animals

Publications (1)

Publication Number Publication Date
CN1649610A true CN1649610A (zh) 2005-08-03

Family

ID=27788020

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA038101599A Pending CN1649610A (zh) 2002-03-07 2003-03-07 一种用于加强温血动物的免疫、抗炎、抗肿瘤以及 d n a修复过程的植物水溶性提取物生物活性组分的分离纯化以及结构鉴定

Country Status (11)

Country Link
US (7) US6964784B2 (OSRAM)
EP (1) EP1485114A2 (OSRAM)
JP (1) JP2005526053A (OSRAM)
KR (1) KR20040099300A (OSRAM)
CN (1) CN1649610A (OSRAM)
AU (1) AU2003207894A1 (OSRAM)
BR (1) BRPI0308253A2 (OSRAM)
CA (1) CA2477785A1 (OSRAM)
IL (1) IL163886A0 (OSRAM)
MX (1) MXPA04008567A (OSRAM)
WO (1) WO2003074062A2 (OSRAM)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102300578A (zh) * 2008-12-01 2011-12-28 延寿有限责任公司 用于改变健康、安康和寿命的方法和组合物
CN109847071A (zh) * 2017-11-30 2019-06-07 奥普特吉尼克斯有限公司 增加细胞中的端粒长度
CN113759067A (zh) * 2021-08-06 2021-12-07 北京康仁堂药业有限公司 一种薄层色谱的构建方法和鉴定方法及其应用

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002042429A2 (en) * 2000-11-03 2002-05-30 Proteotech, Inc. Methods of isolating amyloid-inhibiting compounds and use of compounds isolated from uncaria tomentosa and related plants
US6964784B2 (en) * 2002-03-07 2005-11-15 Optigenex, Inc. Method of preparation and composition of a water soluble extract of the bioactive component of the plant species uncaria for enhancing immune, anti-inflammatory, anti-tumor and dna repair processes of warm blooded animals
EP1631304A4 (en) 2003-04-04 2007-03-21 Unigen Pharmaceuticals Inc FORMULATION OF DUAL CYCLOXYGENASE (COX) AND LIPOXYGENASE (LOX) INHIBITORS FOR THE SKIN CARE OF MAMMALS
WO2005094773A1 (es) † 2004-04-01 2005-10-13 Industrial Farmaceutica Cantabria, S.A. Composiciones fotoprotectoras y/o fotoinmunoprotectoras de la piel y sus usos
US20050226825A1 (en) * 2004-04-13 2005-10-13 Giampapa Vincent C Topical composition for preventing and treating skin damage caused by UV light exposure
US20050287227A1 (en) * 2004-04-16 2005-12-29 Ronald Pero Supplement containing carotenoid, nicotinamide, zinc, water soluble extract of uncaria species and method of the same
KR100545304B1 (ko) * 2004-09-01 2006-05-08 주식회사 유니젠 아선약을 포함하는 운카리아 속 식물, 또는 이의 황금및/또는 녹차의 배합물을 포함하는 사이클로옥시게나제및/또는 5-리폭시게나제 억제용 조성물
MX2007011200A (es) * 2005-03-16 2008-04-02 Ronald W Pero Composiciones medicinales de sales, quelatos y/o acidos libres de acidos organicos de alfa-hidroxilo y procesos y metodos relacionados.
US20090035395A1 (en) * 2007-08-01 2009-02-05 Peter Koepke Spondias mombin l. extract and methods of extracting and using such extract
US7879369B2 (en) 2007-09-18 2011-02-01 Selvamedica, Llc Combretum laurifolium Mart. extract and methods of extracting and using such extract
JP5660898B2 (ja) * 2007-11-09 2015-01-28 ユニバーシティ オブ テネシー リサーチ ファウンデーション 経口投与用の抗炎症性キナ酸誘導体
US8911774B2 (en) * 2009-05-18 2014-12-16 Cellhealth Technologies Ltd. Topical composition for anti-aging skin treatment using dual DNA repair mechanism and method of use
US9457009B2 (en) 2012-05-31 2016-10-04 The United States Of America As Represented By The Department Of Veterans Affairs Methods and compositions for preventing and treating auditory dysfunctions
CN105050708A (zh) 2012-11-14 2015-11-11 格雷斯公司 含有生物活性材料与无序无机氧化物的组合物
AU2016227767A1 (en) * 2015-03-03 2017-07-27 Société des Produits Nestlé S.A. Compound use in promoting energy expenditure

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE538512A (OSRAM) * 1954-05-28
DE1905875A1 (de) * 1969-02-06 1970-08-20 Stark Dr Hans C Mittel,hergestellt durch die Kombination verschiedener chemischer Koerper,das die Regulierung und vorzeitige Hervorrufung der Periodenblutung bewirkt sowie im Klimakterium die Menstruation nach dem Stillstand wieder hervorruft und fuer mehrere Jahre verlaengert
US4363815A (en) * 1975-07-23 1982-12-14 Yu Ruey J Alpha hydroxyacids, alpha ketoacids and their use in treating skin conditions
US5389677B1 (en) * 1986-12-23 1997-07-15 Tristrata Inc Method of treating wrinkles using glycalic acid
US5385938B1 (en) * 1986-12-23 1997-07-15 Tristrata Inc Method of using glycolic acid for treating wrinkles
US4940803A (en) * 1988-05-23 1990-07-10 Merck & Co., Inc. Process for synthesis of 1R,2R,5R-2-hydroxy-6-oxo-7-oxabicyclo[3.2.1]-octane
DE69228542T2 (de) * 1992-08-03 1999-07-29 Societe Des Produits Nestle S.A., Vevey 3- und/oder 4-substituierte Chinasäurederivate und Verfahren zur Herstellung von 3- und/oder 4-substituierten Chinasäurederivaten
US5952375A (en) * 1995-02-27 1999-09-14 Gilead Sciences, Inc. Compounds and methods for synthesis and therapy
US6238675B1 (en) * 1997-02-27 2001-05-29 Campamed Corp. Method of preparation and composition of a water soluble extract of the plant species Uncaria for enhancing immune, anti-inflammatory and anti-tumor processes of warm blooded animals
US6039949A (en) * 1997-02-27 2000-03-21 Campamed, Inc. Method of preparation and composition of a water soluble extract of the plant species uncaria
US5843928A (en) * 1997-03-17 1998-12-01 Wisconsin Alumni Research Foundation 2-alkylidene-19-nor-vitamin D compounds
TW477783B (en) * 1997-12-12 2002-03-01 Gilead Sciences Inc Novel compounds useful as neuraminidase inhibitors and pharmaceutical compositions containing same
JPH11245503A (ja) * 1998-03-02 1999-09-14 Bando Chem Ind Ltd 水性インク吸収材及び該吸収材の層を有する積層フィルム
PT1176195E (pt) * 1999-04-09 2013-07-18 Kyowa Hakko Kirin Co Ltd Processo para controlar a actividade de uma molécula funcional sob o ponto de vista imunológico
US6723368B1 (en) * 1999-12-21 2004-04-20 Loretta M. Zapp Method for enhancing post-processing content of beneficial compounds in beverages naturally containing same
US20010047032A1 (en) * 1999-12-30 2001-11-29 Castillo Gerardo M. Polyhydroxylated aromatic compounds for the treatment of amyloidosis and alpha-synuclein fibril diseases
US6410246B1 (en) * 2000-06-23 2002-06-25 Genetastix Corporation Highly diverse library of yeast expression vectors
US7863020B2 (en) * 2000-06-28 2011-01-04 Glycofi, Inc. Production of sialylated N-glycans in lower eukaryotes
US20060034830A1 (en) * 2000-06-28 2006-02-16 Gerngross Tillman U Immunoglobulins comprising predominantly a GalGlcNAcMan5GLcNAc2 glycoform
US7449308B2 (en) * 2000-06-28 2008-11-11 Glycofi, Inc. Combinatorial DNA library for producing modified N-glycans in lower eukaryotes
US7625756B2 (en) * 2000-06-28 2009-12-01 GycoFi, Inc. Expression of class 2 mannosidase and class III mannosidase in lower eukaryotic cells
US20060029604A1 (en) * 2000-06-28 2006-02-09 Gerngross Tillman U Immunoglobulins comprising predominantly a GlcNAc2Man3GlcNAc2 glycoform
US20060034828A1 (en) * 2000-06-28 2006-02-16 Gerngross Tillman U Immunoglobulins comprising predominantly a GlcNAcMAN5GLCNAC2 glycoform
US7795002B2 (en) * 2000-06-28 2010-09-14 Glycofi, Inc. Production of galactosylated glycoproteins in lower eukaryotes
US7598055B2 (en) * 2000-06-28 2009-10-06 Glycofi, Inc. N-acetylglucosaminyltransferase III expression in lower eukaryotes
US20060024304A1 (en) * 2000-06-28 2006-02-02 Gerngross Tillman U Immunoglobulins comprising predominantly a Man5GlcNAc2 glycoform
ATE440959T1 (de) * 2000-06-28 2009-09-15 Glycofi Inc Verfahren für die herstellung modifizierter glykoproteine
GB0108903D0 (en) * 2000-10-05 2001-05-30 Aventis Pharm Prod Inc Novel crystalline forms of a factor Xa inhibitor
US7064191B2 (en) * 2000-10-06 2006-06-20 Kyowa Hakko Kogyo Co., Ltd. Process for purifying antibody
US6632459B2 (en) * 2000-12-11 2003-10-14 Nutricia N.V. Chlorogenic acid and an analog thereof for immune system stimulation
CA2347879A1 (en) * 2001-05-11 2002-11-11 Vanderbilt University Substituted dicinnamoylquinides and their use in augmentation of adenosine function
EP2359685B1 (en) * 2001-12-27 2013-12-04 GlycoFi, Inc. Methods to engineer mammalian-type carbohydrate structures
US20060034829A1 (en) * 2001-12-27 2006-02-16 Gerngross Tillman U Immunoglobulins comprising predominantly a MAN3GLCNAC2 glycoform
US20060024292A1 (en) * 2001-12-27 2006-02-02 Gerngross Tillman U Immunoglobulins comprising predominantly a Gal2GlcNAc2Man3GlcNAc2 glycoform
US6964784B2 (en) * 2002-03-07 2005-11-15 Optigenex, Inc. Method of preparation and composition of a water soluble extract of the bioactive component of the plant species uncaria for enhancing immune, anti-inflammatory, anti-tumor and dna repair processes of warm blooded animals
US7332299B2 (en) * 2003-02-20 2008-02-19 Glycofi, Inc. Endomannosidases in the modification of glycoproteins in eukaryotes
CA2551484C (en) * 2003-12-24 2015-03-31 Glycofi, Inc. Methods for eliminating mannosylphosphorylation of glycans in the production of glycoproteins
WO2005090552A2 (en) * 2004-03-17 2005-09-29 Glycofi, Inc. Method of engineering a cytidine monophosphate-sialic acid synthetic pathway in fungi and yeast
CN101084233B (zh) * 2004-04-29 2012-08-15 格利科菲公司 用于在糖蛋白产生中减少或消除α-甘露糖苷酶抗性聚糖的方法

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102300578A (zh) * 2008-12-01 2011-12-28 延寿有限责任公司 用于改变健康、安康和寿命的方法和组合物
CN109847071A (zh) * 2017-11-30 2019-06-07 奥普特吉尼克斯有限公司 增加细胞中的端粒长度
CN109847071B (zh) * 2017-11-30 2022-07-19 奥普特吉尼克斯有限公司 增加细胞中的端粒长度
CN113759067A (zh) * 2021-08-06 2021-12-07 北京康仁堂药业有限公司 一种薄层色谱的构建方法和鉴定方法及其应用

Also Published As

Publication number Publication date
KR20040099300A (ko) 2004-11-26
CA2477785A1 (en) 2003-09-12
US20110245337A1 (en) 2011-10-06
US8372449B2 (en) 2013-02-12
WO2003074062A2 (en) 2003-09-12
US20050176825A1 (en) 2005-08-11
AU2003207894A1 (en) 2003-09-16
US7947312B2 (en) 2011-05-24
BRPI0308253A2 (pt) 2016-07-12
US20090298939A1 (en) 2009-12-03
US6964784B2 (en) 2005-11-15
US20110263706A1 (en) 2011-10-27
US20060068035A1 (en) 2006-03-30
JP2005526053A (ja) 2005-09-02
MXPA04008567A (es) 2004-12-06
US7595064B2 (en) 2009-09-29
US7955626B2 (en) 2011-06-07
EP1485114A2 (en) 2004-12-15
US8372448B2 (en) 2013-02-12
IL163886A0 (en) 2005-12-18
WO2003074062A3 (en) 2004-02-05
US7579023B2 (en) 2009-08-25
US20090281180A1 (en) 2009-11-12
US20030170320A1 (en) 2003-09-11

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