CA2477785A1 - Isolation, purification and structural identification of a bioactive component of a water soluble extract of a botanical species for enhancing immune, anti-inflammatory, anti-tumor and dna repair processes of warm blooded animals - Google Patents

Isolation, purification and structural identification of a bioactive component of a water soluble extract of a botanical species for enhancing immune, anti-inflammatory, anti-tumor and dna repair processes of warm blooded animals Download PDF

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Publication number
CA2477785A1
CA2477785A1 CA002477785A CA2477785A CA2477785A1 CA 2477785 A1 CA2477785 A1 CA 2477785A1 CA 002477785 A CA002477785 A CA 002477785A CA 2477785 A CA2477785 A CA 2477785A CA 2477785 A1 CA2477785 A1 CA 2477785A1
Authority
CA
Canada
Prior art keywords
mammal
extract
bioactive component
quinic acid
pharmaceutical composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002477785A
Other languages
English (en)
French (fr)
Inventor
Ronald W. Pero
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Optigenex Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27788020&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2477785(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Individual filed Critical Individual
Publication of CA2477785A1 publication Critical patent/CA2477785A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/74—Rubiaceae (Madder family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
CA002477785A 2002-03-07 2003-03-07 Isolation, purification and structural identification of a bioactive component of a water soluble extract of a botanical species for enhancing immune, anti-inflammatory, anti-tumor and dna repair processes of warm blooded animals Abandoned CA2477785A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/093,794 2002-03-07
US10/093,794 US6964784B2 (en) 2002-03-07 2002-03-07 Method of preparation and composition of a water soluble extract of the bioactive component of the plant species uncaria for enhancing immune, anti-inflammatory, anti-tumor and dna repair processes of warm blooded animals
PCT/IB2003/000824 WO2003074062A2 (en) 2002-03-07 2003-03-07 Isolation, purification and structural identification of a bioactive component of a water soluble extract of a botanical species for enhancing immune, anti-inflammatory, anti-tumor and dna repair processes of warm blooded animals

Publications (1)

Publication Number Publication Date
CA2477785A1 true CA2477785A1 (en) 2003-09-12

Family

ID=27788020

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002477785A Abandoned CA2477785A1 (en) 2002-03-07 2003-03-07 Isolation, purification and structural identification of a bioactive component of a water soluble extract of a botanical species for enhancing immune, anti-inflammatory, anti-tumor and dna repair processes of warm blooded animals

Country Status (11)

Country Link
US (7) US6964784B2 (OSRAM)
EP (1) EP1485114A2 (OSRAM)
JP (1) JP2005526053A (OSRAM)
KR (1) KR20040099300A (OSRAM)
CN (1) CN1649610A (OSRAM)
AU (1) AU2003207894A1 (OSRAM)
BR (1) BRPI0308253A2 (OSRAM)
CA (1) CA2477785A1 (OSRAM)
IL (1) IL163886A0 (OSRAM)
MX (1) MXPA04008567A (OSRAM)
WO (1) WO2003074062A2 (OSRAM)

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WO2002042429A2 (en) * 2000-11-03 2002-05-30 Proteotech, Inc. Methods of isolating amyloid-inhibiting compounds and use of compounds isolated from uncaria tomentosa and related plants
US6964784B2 (en) * 2002-03-07 2005-11-15 Optigenex, Inc. Method of preparation and composition of a water soluble extract of the bioactive component of the plant species uncaria for enhancing immune, anti-inflammatory, anti-tumor and dna repair processes of warm blooded animals
EP1631304A4 (en) 2003-04-04 2007-03-21 Unigen Pharmaceuticals Inc FORMULATION OF DUAL CYCLOXYGENASE (COX) AND LIPOXYGENASE (LOX) INHIBITORS FOR THE SKIN CARE OF MAMMALS
WO2005094773A1 (es) † 2004-04-01 2005-10-13 Industrial Farmaceutica Cantabria, S.A. Composiciones fotoprotectoras y/o fotoinmunoprotectoras de la piel y sus usos
US20050226825A1 (en) * 2004-04-13 2005-10-13 Giampapa Vincent C Topical composition for preventing and treating skin damage caused by UV light exposure
US20050287227A1 (en) * 2004-04-16 2005-12-29 Ronald Pero Supplement containing carotenoid, nicotinamide, zinc, water soluble extract of uncaria species and method of the same
KR100545304B1 (ko) * 2004-09-01 2006-05-08 주식회사 유니젠 아선약을 포함하는 운카리아 속 식물, 또는 이의 황금및/또는 녹차의 배합물을 포함하는 사이클로옥시게나제및/또는 5-리폭시게나제 억제용 조성물
MX2007011200A (es) * 2005-03-16 2008-04-02 Ronald W Pero Composiciones medicinales de sales, quelatos y/o acidos libres de acidos organicos de alfa-hidroxilo y procesos y metodos relacionados.
US20090035395A1 (en) * 2007-08-01 2009-02-05 Peter Koepke Spondias mombin l. extract and methods of extracting and using such extract
US7879369B2 (en) 2007-09-18 2011-02-01 Selvamedica, Llc Combretum laurifolium Mart. extract and methods of extracting and using such extract
JP5660898B2 (ja) * 2007-11-09 2015-01-28 ユニバーシティ オブ テネシー リサーチ ファウンデーション 経口投与用の抗炎症性キナ酸誘導体
EP2370086A2 (en) * 2008-12-01 2011-10-05 Lifespan Extension Llc Methods and compositions for altering health, wellbeing, and lifespan
US8911774B2 (en) * 2009-05-18 2014-12-16 Cellhealth Technologies Ltd. Topical composition for anti-aging skin treatment using dual DNA repair mechanism and method of use
US9457009B2 (en) 2012-05-31 2016-10-04 The United States Of America As Represented By The Department Of Veterans Affairs Methods and compositions for preventing and treating auditory dysfunctions
CN105050708A (zh) 2012-11-14 2015-11-11 格雷斯公司 含有生物活性材料与无序无机氧化物的组合物
AU2016227767A1 (en) * 2015-03-03 2017-07-27 Société des Produits Nestlé S.A. Compound use in promoting energy expenditure
US10098922B1 (en) 2017-11-30 2018-10-16 Optigenex, Inc. Increasing telomere length in a cell
CN113759067A (zh) * 2021-08-06 2021-12-07 北京康仁堂药业有限公司 一种薄层色谱的构建方法和鉴定方法及其应用

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DE1905875A1 (de) * 1969-02-06 1970-08-20 Stark Dr Hans C Mittel,hergestellt durch die Kombination verschiedener chemischer Koerper,das die Regulierung und vorzeitige Hervorrufung der Periodenblutung bewirkt sowie im Klimakterium die Menstruation nach dem Stillstand wieder hervorruft und fuer mehrere Jahre verlaengert
US4363815A (en) * 1975-07-23 1982-12-14 Yu Ruey J Alpha hydroxyacids, alpha ketoacids and their use in treating skin conditions
US5389677B1 (en) * 1986-12-23 1997-07-15 Tristrata Inc Method of treating wrinkles using glycalic acid
US5385938B1 (en) * 1986-12-23 1997-07-15 Tristrata Inc Method of using glycolic acid for treating wrinkles
US4940803A (en) * 1988-05-23 1990-07-10 Merck & Co., Inc. Process for synthesis of 1R,2R,5R-2-hydroxy-6-oxo-7-oxabicyclo[3.2.1]-octane
DE69228542T2 (de) * 1992-08-03 1999-07-29 Societe Des Produits Nestle S.A., Vevey 3- und/oder 4-substituierte Chinasäurederivate und Verfahren zur Herstellung von 3- und/oder 4-substituierten Chinasäurederivaten
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PT1176195E (pt) * 1999-04-09 2013-07-18 Kyowa Hakko Kirin Co Ltd Processo para controlar a actividade de uma molécula funcional sob o ponto de vista imunológico
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US6410246B1 (en) * 2000-06-23 2002-06-25 Genetastix Corporation Highly diverse library of yeast expression vectors
US7863020B2 (en) * 2000-06-28 2011-01-04 Glycofi, Inc. Production of sialylated N-glycans in lower eukaryotes
US20060034830A1 (en) * 2000-06-28 2006-02-16 Gerngross Tillman U Immunoglobulins comprising predominantly a GalGlcNAcMan5GLcNAc2 glycoform
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Also Published As

Publication number Publication date
KR20040099300A (ko) 2004-11-26
US20110245337A1 (en) 2011-10-06
US8372449B2 (en) 2013-02-12
WO2003074062A2 (en) 2003-09-12
US20050176825A1 (en) 2005-08-11
AU2003207894A1 (en) 2003-09-16
US7947312B2 (en) 2011-05-24
BRPI0308253A2 (pt) 2016-07-12
US20090298939A1 (en) 2009-12-03
US6964784B2 (en) 2005-11-15
US20110263706A1 (en) 2011-10-27
US20060068035A1 (en) 2006-03-30
JP2005526053A (ja) 2005-09-02
MXPA04008567A (es) 2004-12-06
US7595064B2 (en) 2009-09-29
US7955626B2 (en) 2011-06-07
EP1485114A2 (en) 2004-12-15
US8372448B2 (en) 2013-02-12
IL163886A0 (en) 2005-12-18
WO2003074062A3 (en) 2004-02-05
CN1649610A (zh) 2005-08-03
US7579023B2 (en) 2009-08-25
US20090281180A1 (en) 2009-11-12
US20030170320A1 (en) 2003-09-11

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EEER Examination request
FZDE Discontinued