CN1622832A - 用于动脉粥样硬化和易病变性斑块成像的标记的巨噬细胞清除剂受体拮抗剂 - Google Patents
用于动脉粥样硬化和易病变性斑块成像的标记的巨噬细胞清除剂受体拮抗剂 Download PDFInfo
- Publication number
- CN1622832A CN1622832A CNA028087704A CN02808770A CN1622832A CN 1622832 A CN1622832 A CN 1622832A CN A028087704 A CNA028087704 A CN A028087704A CN 02808770 A CN02808770 A CN 02808770A CN 1622832 A CN1622832 A CN 1622832A
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- China
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- substituted
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- independently selected
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Optics & Photonics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27095401P | 2001-02-23 | 2001-02-23 | |
| US60/270,954 | 2001-02-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1622832A true CN1622832A (zh) | 2005-06-01 |
Family
ID=23033552
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA028087704A Pending CN1622832A (zh) | 2001-02-23 | 2002-02-22 | 用于动脉粥样硬化和易病变性斑块成像的标记的巨噬细胞清除剂受体拮抗剂 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US6869590B2 (enExample) |
| EP (1) | EP1377321A4 (enExample) |
| JP (1) | JP2004530654A (enExample) |
| CN (1) | CN1622832A (enExample) |
| AU (1) | AU2002254000A1 (enExample) |
| BR (1) | BR0207521A (enExample) |
| CA (1) | CA2438174A1 (enExample) |
| CZ (1) | CZ20032564A3 (enExample) |
| HU (1) | HUP0400027A3 (enExample) |
| IL (1) | IL157444A0 (enExample) |
| MX (1) | MXPA03007534A (enExample) |
| WO (1) | WO2002067761A2 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116473020A (zh) * | 2022-11-18 | 2023-07-25 | 新乡医学院 | 一种Macrosialin基因缺失动脉粥样硬化小鼠模型的构建方法及其应用 |
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| MXPA03010035A (es) * | 2001-05-02 | 2004-06-30 | Purdue Research Foundation | Tratamiento y diagnostico de enfermedades mediadas por macrofagos. |
| CA2449828A1 (en) * | 2001-06-04 | 2003-01-16 | The General Hospital Corporation | Detection and therapy of vulnerable plaque with photodynamic compounds |
| CA2461836A1 (en) * | 2001-10-16 | 2003-04-24 | Epix Medical, Inc. | Detection and treatment of intravascular lesions |
| US8043603B2 (en) | 2002-02-07 | 2011-10-25 | Endocyte, Inc. | Folate targeted enhanced tumor and folate receptor positive tissue optical imaging technology |
| US8043602B2 (en) | 2002-02-07 | 2011-10-25 | Endocyte, Inc. | Folate targeted enhanced tumor and folate receptor positive tissue optical imaging technology |
| AU2002337926B8 (en) * | 2002-11-05 | 2008-02-28 | Ion Beam Applications S.A. | Stabilization of radiopharmaceuticals labeled with 18-F |
| US7018614B2 (en) * | 2002-11-05 | 2006-03-28 | Eastern Isotopes, Inc. | Stabilization of radiopharmaceuticals labeled with 18-F |
| GB0228490D0 (en) * | 2002-12-06 | 2003-01-08 | Amersham Plc | Novel imaging compounds |
| US7297154B2 (en) | 2003-02-24 | 2007-11-20 | Maxwell Sensors Inc. | Optical apparatus for detecting and treating vulnerable plaque |
| US7153299B1 (en) | 2003-02-24 | 2006-12-26 | Maxwell Sensors Inc. | Optical apparatus for detecting and treating vulnerable plaque |
| US7803352B2 (en) * | 2003-03-07 | 2010-09-28 | John Steele Fisher | Method for continuous visualization of a blood clot or plaque in body lumen |
| JP4680185B2 (ja) | 2003-05-30 | 2011-05-11 | パーデュー・リサーチ・ファウンデーション | アテローム性動脈硬化症の診断法 |
| CN1859904A (zh) * | 2003-10-03 | 2006-11-08 | 默克公司 | 用于治疗阿尔茨海默氏病的苄醚和苄氨基β-分泌酶抑制剂 |
| EP1602931A1 (en) * | 2004-06-03 | 2005-12-07 | Universiteit Leiden | SR-A antagonists |
| US20080206150A1 (en) * | 2004-06-25 | 2008-08-28 | The Regents Of The University Of California | Nanoparticles for Imaging Atherosclerotic Plaque |
| US7575738B2 (en) | 2004-08-13 | 2009-08-18 | General Electric Company | Heat shock protein as a targeting agent for endothelium-specific in vivo transduction |
| RU2007128036A (ru) * | 2004-12-23 | 2009-01-27 | Пердью Рисерч Фаундейшн (Us) | Способ получения изображения позитронно-эмиссионной томографией |
| EP1904183B1 (en) | 2005-07-05 | 2014-10-15 | Purdue Research Foundation | Pharmaceutical composition for the treatment of osteoarthritis |
| US7874975B2 (en) * | 2005-07-20 | 2011-01-25 | Clear Vascular, Inc. | Methods and compositions for treating luminal inflammatory disease |
| WO2007038346A2 (en) | 2005-09-23 | 2007-04-05 | Purdue Research Foundation | Multiphoton in vivo flow cytometry method and device |
| US20070196282A1 (en) * | 2006-02-21 | 2007-08-23 | Siemens Medical Solutions Usa, Inc. | Medical diagnostic ultrasound with temperature-dependent contrast agents |
| EP2087337A4 (en) | 2006-11-03 | 2010-09-08 | Purdue Research Foundation | METHOD AND DEVICE FOR EX-VIVO FLOW CYTOMETRY |
| EP2109466B1 (en) | 2007-02-07 | 2014-11-12 | Purdue Research Foundation | Positron emission tomography imaging method |
| US8961926B2 (en) * | 2007-05-25 | 2015-02-24 | Purdue Research Foundation | Method of imaging localized infections |
| RU2474435C2 (ru) * | 2007-11-07 | 2013-02-10 | Джи-И Хелткер БВ | Стабилизация радиофармацевтических композиций |
| US9717896B2 (en) | 2007-12-18 | 2017-08-01 | Gearbox, Llc | Treatment indications informed by a priori implant information |
| US20090287120A1 (en) | 2007-12-18 | 2009-11-19 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Circulatory monitoring systems and methods |
| US8636670B2 (en) | 2008-05-13 | 2014-01-28 | The Invention Science Fund I, Llc | Circulatory monitoring systems and methods |
| US8361438B2 (en) * | 2008-01-08 | 2013-01-29 | Lantheus Medical Imaging, Inc. | N-alkoxyamide conjugates as imaging agents |
| US20100178245A1 (en) * | 2009-01-13 | 2010-07-15 | Arnsdorf Morton F | Biocompatible Microbubbles to Deliver Radioactive Compounds to Tumors, Atherosclerotic Plaques, Joints and Other Targeted Sites |
| EP2451776B1 (en) | 2009-07-08 | 2019-09-18 | Lantheus Medical Imaging, Inc. | N-alkoxyamide conjugates as imaging agents |
| US20150023873A1 (en) | 2011-11-11 | 2015-01-22 | Lantheus Medical Imaging, Inc. | Evaluation of presence of and vulnerability to atrial fibrillation and other indications using matrix metalloproteinase-based imaging |
| DE112016001921B4 (de) | 2015-06-09 | 2025-03-20 | Cummins Filtration Ip, Inc. | Kurbelgehäuseentlüftungssysteme, die rotierende Tropfenabscheidervorrichtungen verwenden |
| WO2019034500A1 (en) * | 2017-08-15 | 2019-02-21 | Koninklijke Philips N.V. | INTRALUMINAL ULTRASONIC DEVICE WITH ADJUSTABLE FREQUENCY |
| US10933146B2 (en) * | 2017-12-12 | 2021-03-02 | Massachusetts Institute Of Technology | Cell-permeable imaging sensors and uses thereof |
| KR102207372B1 (ko) * | 2020-03-31 | 2021-01-27 | 재단법인 아산사회복지재단 | 방사성 의약품의 안정화제 및 이를 포함하는 방사성 의약 조성물 |
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| US4577042A (en) * | 1983-03-17 | 1986-03-18 | California Institute Of Technology | Homogeneous coordination compounds as oxidation catalysts |
| US4678667A (en) | 1985-07-02 | 1987-07-07 | 501 Regents of the University of California | Macrocyclic bifunctional chelating agents |
| US4752141A (en) | 1985-10-25 | 1988-06-21 | Luxtron Corporation | Fiberoptic sensing of temperature and/or other physical parameters |
| EP0247156B1 (en) | 1985-11-18 | 1993-06-23 | Access Pharmaceuticals Inc. | Polychelating agents for image and spectral enhancement (and spectral shift) |
| MX174467B (es) | 1986-01-23 | 1994-05-17 | Squibb & Sons Inc | 1,4,7-triscarboximetil-1,4,7,10-tetraazaciclodo decano substituido en 1 y compuestos analogos |
| US4885363A (en) | 1987-04-24 | 1989-12-05 | E. R. Squibb & Sons, Inc. | 1-substituted-1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclododecane and analogs |
| GB8603537D0 (en) | 1986-02-13 | 1986-03-19 | Parker D | Conjugate compound |
| GB8719042D0 (en) | 1987-08-12 | 1987-09-16 | Parker D | Conjugate compounds |
| US4923985A (en) | 1988-05-25 | 1990-05-08 | The United States Of America As Represented By The Department Of Health & Human Services | Process for synthesizing macrocyclic chelates |
| EP0416033B1 (en) | 1988-05-25 | 1996-03-06 | THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce | Macrocyclic chelates and methods of use thereof |
| US5756065A (en) | 1988-06-24 | 1998-05-26 | The Dow Chemical Company | Macrocyclic tetraazacyclododecane conjugates and their use as diagnostic and therapeutic agents |
| LU87403A1 (fr) | 1988-12-06 | 1990-07-10 | Oreal | Procede de teinture de fibres keratiniques avec un hydroxyindole,associe a un derive quinonique |
| DE69024826T2 (de) | 1989-02-10 | 1996-06-27 | Celltech Therapeutics Ltd | Aza-Macrozyklen und Verfahren zu deren Herstellung |
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| AU7587091A (en) | 1990-03-26 | 1991-10-21 | United States of America, as represented by the Secretary, U.S. Department of Commerce, The | A fonctionalized complexand |
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| EP0565930A1 (en) | 1992-03-27 | 1993-10-20 | Nihon Medi-Physics Co., Ltd. | Tetraazacyclododecane tetraacetic acid derivatives and the use thereof as diagnostic agents |
| US5310535A (en) | 1992-04-24 | 1994-05-10 | The Dow Chemical Company | Carboxamide modified polyamine chelators and radioactive complexes thereof for conjugation to antibodies |
| US5744120A (en) | 1993-03-30 | 1998-04-28 | The Dupont Merick Pharmaceutical Company | Ternary radiopharmaceutical complexes |
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| AU2194695A (en) | 1994-03-28 | 1995-10-17 | Regents Of The University Of California, The | Method for preparing radionuclide-labeled chelating agent-ligand complexes |
| IT1283218B1 (it) | 1996-03-08 | 1998-04-16 | Bracco Spa | Polichelanti, loro complessi con ioni metallici, loro preparazione e loro usi |
| US5879659A (en) | 1996-03-13 | 1999-03-09 | Dupont Pharmaceuticals Company | Ternary radiopharmaceutical complexes |
| US5848367A (en) | 1996-09-13 | 1998-12-08 | Sony Corporation | System and method for sharing a non-volatile memory element as a boot device |
| US6403054B1 (en) | 1997-05-28 | 2002-06-11 | Bristol-Myers Squibb Pharma Company | Ternary ligand complexes useful as radiopharmaceuticals |
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| CA2328457A1 (en) | 1998-06-20 | 1999-12-29 | Washington University | Membrane-permeant peptide complexes for medical imaging, diagnostics, and pharmaceutical therapy |
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| JP2002521437A (ja) | 1998-07-30 | 2002-07-16 | スミスクライン・ビーチャム・コーポレイション | マクロファージ・スカベンジャー受容体アンタゴニスト |
-
2002
- 2002-02-22 JP JP2002567138A patent/JP2004530654A/ja active Pending
- 2002-02-22 MX MXPA03007534A patent/MXPA03007534A/es active IP Right Grant
- 2002-02-22 AU AU2002254000A patent/AU2002254000A1/en not_active Abandoned
- 2002-02-22 EP EP02723207A patent/EP1377321A4/en not_active Withdrawn
- 2002-02-22 IL IL15744402A patent/IL157444A0/xx unknown
- 2002-02-22 BR BR0207521-0A patent/BR0207521A/pt not_active IP Right Cessation
- 2002-02-22 CA CA002438174A patent/CA2438174A1/en not_active Abandoned
- 2002-02-22 CN CNA028087704A patent/CN1622832A/zh active Pending
- 2002-02-22 CZ CZ20032564A patent/CZ20032564A3/cs unknown
- 2002-02-22 WO PCT/US2002/005156 patent/WO2002067761A2/en not_active Ceased
- 2002-02-22 HU HU0400027A patent/HUP0400027A3/hu unknown
- 2002-02-22 US US10/080,974 patent/US6869590B2/en not_active Expired - Fee Related
-
2003
- 2003-08-14 US US10/641,688 patent/US6974567B2/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116473020A (zh) * | 2022-11-18 | 2023-07-25 | 新乡医学院 | 一种Macrosialin基因缺失动脉粥样硬化小鼠模型的构建方法及其应用 |
Also Published As
| Publication number | Publication date |
|---|---|
| BR0207521A (pt) | 2004-06-01 |
| IL157444A0 (en) | 2004-03-28 |
| AU2002254000A1 (en) | 2002-09-12 |
| JP2004530654A (ja) | 2004-10-07 |
| EP1377321A2 (en) | 2004-01-07 |
| US6974567B2 (en) | 2005-12-13 |
| US20040057900A1 (en) | 2004-03-25 |
| MXPA03007534A (es) | 2003-12-04 |
| CA2438174A1 (en) | 2002-09-06 |
| US20020127181A1 (en) | 2002-09-12 |
| HUP0400027A2 (hu) | 2004-04-28 |
| US6869590B2 (en) | 2005-03-22 |
| CZ20032564A3 (cs) | 2004-09-15 |
| WO2002067761A2 (en) | 2002-09-06 |
| EP1377321A4 (en) | 2006-01-11 |
| WO2002067761A3 (en) | 2003-02-13 |
| HUP0400027A3 (en) | 2006-01-30 |
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| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C12 | Rejection of a patent application after its publication | ||
| RJ01 | Rejection of invention patent application after publication |