JP2004530654A - アテローム硬化症および脆弱性プラークを画像診断するための標識マクロファージスカベンジャー受容体拮抗薬 - Google Patents
アテローム硬化症および脆弱性プラークを画像診断するための標識マクロファージスカベンジャー受容体拮抗薬 Download PDFInfo
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Optics & Photonics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| US27095401P | 2001-02-23 | 2001-02-23 | |
| PCT/US2002/005156 WO2002067761A2 (en) | 2001-02-23 | 2002-02-22 | Labeled macrophage scavenger receptor antagonists for imaging atherosclerosis and vulnerable plaque |
Publications (2)
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| JP2004530654A true JP2004530654A (ja) | 2004-10-07 |
| JP2004530654A5 JP2004530654A5 (enExample) | 2008-03-27 |
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| EP (1) | EP1377321A4 (enExample) |
| JP (1) | JP2004530654A (enExample) |
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| BR (1) | BR0207521A (enExample) |
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| HU (1) | HUP0400027A3 (enExample) |
| IL (1) | IL157444A0 (enExample) |
| MX (1) | MXPA03007534A (enExample) |
| WO (1) | WO2002067761A2 (enExample) |
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| MXPA03010035A (es) * | 2001-05-02 | 2004-06-30 | Purdue Research Foundation | Tratamiento y diagnostico de enfermedades mediadas por macrofagos. |
| CA2449828A1 (en) * | 2001-06-04 | 2003-01-16 | The General Hospital Corporation | Detection and therapy of vulnerable plaque with photodynamic compounds |
| CA2461836A1 (en) * | 2001-10-16 | 2003-04-24 | Epix Medical, Inc. | Detection and treatment of intravascular lesions |
| US8043603B2 (en) | 2002-02-07 | 2011-10-25 | Endocyte, Inc. | Folate targeted enhanced tumor and folate receptor positive tissue optical imaging technology |
| US8043602B2 (en) | 2002-02-07 | 2011-10-25 | Endocyte, Inc. | Folate targeted enhanced tumor and folate receptor positive tissue optical imaging technology |
| AU2002337926B8 (en) * | 2002-11-05 | 2008-02-28 | Ion Beam Applications S.A. | Stabilization of radiopharmaceuticals labeled with 18-F |
| US7018614B2 (en) * | 2002-11-05 | 2006-03-28 | Eastern Isotopes, Inc. | Stabilization of radiopharmaceuticals labeled with 18-F |
| GB0228490D0 (en) * | 2002-12-06 | 2003-01-08 | Amersham Plc | Novel imaging compounds |
| US7297154B2 (en) | 2003-02-24 | 2007-11-20 | Maxwell Sensors Inc. | Optical apparatus for detecting and treating vulnerable plaque |
| US7153299B1 (en) | 2003-02-24 | 2006-12-26 | Maxwell Sensors Inc. | Optical apparatus for detecting and treating vulnerable plaque |
| US7803352B2 (en) * | 2003-03-07 | 2010-09-28 | John Steele Fisher | Method for continuous visualization of a blood clot or plaque in body lumen |
| JP4680185B2 (ja) | 2003-05-30 | 2011-05-11 | パーデュー・リサーチ・ファウンデーション | アテローム性動脈硬化症の診断法 |
| CN1859904A (zh) * | 2003-10-03 | 2006-11-08 | 默克公司 | 用于治疗阿尔茨海默氏病的苄醚和苄氨基β－分泌酶抑制剂 |
| EP1602931A1 (en) * | 2004-06-03 | 2005-12-07 | Universiteit Leiden | SR-A antagonists |
| US20080206150A1 (en) * | 2004-06-25 | 2008-08-28 | The Regents Of The University Of California | Nanoparticles for Imaging Atherosclerotic Plaque |
| US7575738B2 (en) | 2004-08-13 | 2009-08-18 | General Electric Company | Heat shock protein as a targeting agent for endothelium-specific in vivo transduction |
| RU2007128036A (ru) * | 2004-12-23 | 2009-01-27 | Пердью Рисерч Фаундейшн (Us) | Способ получения изображения позитронно-эмиссионной томографией |
| EP1904183B1 (en) | 2005-07-05 | 2014-10-15 | Purdue Research Foundation | Pharmaceutical composition for the treatment of osteoarthritis |
| US7874975B2 (en) * | 2005-07-20 | 2011-01-25 | Clear Vascular, Inc. | Methods and compositions for treating luminal inflammatory disease |
| WO2007038346A2 (en) | 2005-09-23 | 2007-04-05 | Purdue Research Foundation | Multiphoton in vivo flow cytometry method and device |
| US20070196282A1 (en) * | 2006-02-21 | 2007-08-23 | Siemens Medical Solutions Usa, Inc. | Medical diagnostic ultrasound with temperature-dependent contrast agents |
| EP2087337A4 (en) | 2006-11-03 | 2010-09-08 | Purdue Research Foundation | METHOD AND DEVICE FOR EX-VIVO FLOW CYTOMETRY |
| EP2109466B1 (en) | 2007-02-07 | 2014-11-12 | Purdue Research Foundation | Positron emission tomography imaging method |
| US8961926B2 (en) * | 2007-05-25 | 2015-02-24 | Purdue Research Foundation | Method of imaging localized infections |
| RU2474435C2 (ru) * | 2007-11-07 | 2013-02-10 | Джи-И Хелткер БВ | Стабилизация радиофармацевтических композиций |
| US9717896B2 (en) | 2007-12-18 | 2017-08-01 | Gearbox, Llc | Treatment indications informed by a priori implant information |
| US20090287120A1 (en) | 2007-12-18 | 2009-11-19 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Circulatory monitoring systems and methods |
| US8636670B2 (en) | 2008-05-13 | 2014-01-28 | The Invention Science Fund I, Llc | Circulatory monitoring systems and methods |
| US8361438B2 (en) * | 2008-01-08 | 2013-01-29 | Lantheus Medical Imaging, Inc. | N-alkoxyamide conjugates as imaging agents |
| US20100178245A1 (en) * | 2009-01-13 | 2010-07-15 | Arnsdorf Morton F | Biocompatible Microbubbles to Deliver Radioactive Compounds to Tumors, Atherosclerotic Plaques, Joints and Other Targeted Sites |
| EP2451776B1 (en) | 2009-07-08 | 2019-09-18 | Lantheus Medical Imaging, Inc. | N-alkoxyamide conjugates as imaging agents |
| US20150023873A1 (en) | 2011-11-11 | 2015-01-22 | Lantheus Medical Imaging, Inc. | Evaluation of presence of and vulnerability to atrial fibrillation and other indications using matrix metalloproteinase-based imaging |
| DE112016001921B4 (de) | 2015-06-09 | 2025-03-20 | Cummins Filtration Ip, Inc. | Kurbelgehäuseentlüftungssysteme, die rotierende Tropfenabscheidervorrichtungen verwenden |
| WO2019034500A1 (en) * | 2017-08-15 | 2019-02-21 | Koninklijke Philips N.V. | INTRALUMINAL ULTRASONIC DEVICE WITH ADJUSTABLE FREQUENCY |
| US10933146B2 (en) * | 2017-12-12 | 2021-03-02 | Massachusetts Institute Of Technology | Cell-permeable imaging sensors and uses thereof |
| KR102207372B1 (ko) * | 2020-03-31 | 2021-01-27 | 재단법인 아산사회복지재단 | 방사성 의약품의 안정화제 및 이를 포함하는 방사성 의약 조성물 |
| CN116473020B (zh) * | 2022-11-18 | 2025-04-25 | 新乡医学院 | 一种Macrosialin基因缺失动脉粥样硬化小鼠模型的构建方法及其应用 |
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| US4577042A (en) * | 1983-03-17 | 1986-03-18 | California Institute Of Technology | Homogeneous coordination compounds as oxidation catalysts |
| US4678667A (en) | 1985-07-02 | 1987-07-07 | 501 Regents of the University of California | Macrocyclic bifunctional chelating agents |
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| MX174467B (es) | 1986-01-23 | 1994-05-17 | Squibb & Sons Inc | 1,4,7-triscarboximetil-1,4,7,10-tetraazaciclodo decano substituido en 1 y compuestos analogos |
| US4885363A (en) | 1987-04-24 | 1989-12-05 | E. R. Squibb & Sons, Inc. | 1-substituted-1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclododecane and analogs |
| GB8603537D0 (en) | 1986-02-13 | 1986-03-19 | Parker D | Conjugate compound |
| GB8719042D0 (en) | 1987-08-12 | 1987-09-16 | Parker D | Conjugate compounds |
| US4923985A (en) | 1988-05-25 | 1990-05-08 | The United States Of America As Represented By The Department Of Health & Human Services | Process for synthesizing macrocyclic chelates |
| EP0416033B1 (en) | 1988-05-25 | 1996-03-06 | THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce | Macrocyclic chelates and methods of use thereof |
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| LU87403A1 (fr) | 1988-12-06 | 1990-07-10 | Oreal | Procede de teinture de fibres keratiniques avec un hydroxyindole,associe a un derive quinonique |
| DE69024826T2 (de) | 1989-02-10 | 1996-06-27 | Celltech Therapeutics Ltd | Aza-Macrozyklen und Verfahren zu deren Herstellung |
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| AU7587091A (en) | 1990-03-26 | 1991-10-21 | United States of America, as represented by the Secretary, U.S. Department of Commerce, The | A fonctionalized complexand |
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| US5744120A (en) | 1993-03-30 | 1998-04-28 | The Dupont Merick Pharmaceutical Company | Ternary radiopharmaceutical complexes |
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| AU2194695A (en) | 1994-03-28 | 1995-10-17 | Regents Of The University Of California, The | Method for preparing radionuclide-labeled chelating agent-ligand complexes |
| IT1283218B1 (it) | 1996-03-08 | 1998-04-16 | Bracco Spa | Polichelanti, loro complessi con ioni metallici, loro preparazione e loro usi |
| US5879659A (en) | 1996-03-13 | 1999-03-09 | Dupont Pharmaceuticals Company | Ternary radiopharmaceutical complexes |
| US5848367A (en) | 1996-09-13 | 1998-12-08 | Sony Corporation | System and method for sharing a non-volatile memory element as a boot device |
| US6403054B1 (en) | 1997-05-28 | 2002-06-11 | Bristol-Myers Squibb Pharma Company | Ternary ligand complexes useful as radiopharmaceuticals |
| WO1999007382A1 (en) | 1997-08-06 | 1999-02-18 | Smithkline Beecham Corporation | Macrophage scavenger receptor antagonists for use in the treatment of cardiovascular diseases |
| CA2328457A1 (en) | 1998-06-20 | 1999-12-29 | Washington University | Membrane-permeant peptide complexes for medical imaging, diagnostics, and pharmaceutical therapy |
| WO2000003704A1 (en) * | 1998-07-20 | 2000-01-27 | Smithkline Beecham Corporation | Macrophage scavenger receptor antagonists |
| JP2002521437A (ja) | 1998-07-30 | 2002-07-16 | スミスクライン・ビーチャム・コーポレイション | マクロファージ・スカベンジャー受容体アンタゴニスト |
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| US6869590B2 (en) | 2005-03-22 |
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| EP1377321A4 (en) | 2006-01-11 |
| WO2002067761A3 (en) | 2003-02-13 |
| HUP0400027A3 (en) | 2006-01-30 |
| CN1622832A (zh) | 2005-06-01 |
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