BR0207521A - Antagonistas rotulados de receptores de removedores macrófagos para a geração de imagens de aterosclerose e placa vulnerável - Google Patents
Antagonistas rotulados de receptores de removedores macrófagos para a geração de imagens de aterosclerose e placa vulnerávelInfo
- Publication number
- BR0207521A BR0207521A BR0207521-0A BR0207521A BR0207521A BR 0207521 A BR0207521 A BR 0207521A BR 0207521 A BR0207521 A BR 0207521A BR 0207521 A BR0207521 A BR 0207521A
- Authority
- BR
- Brazil
- Prior art keywords
- atherosclerosis
- vulnerable plaque
- receptor antagonists
- macrophage scavenger
- scavenger receptor
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Optics & Photonics (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
"ANTAGONISTAS ROTULADOS DE RECEPTORES DE REMOVEDORES MACRóFAGOS PARA A GERAçãO DE IMAGENS DE ATEROSCLEROSE E PLACA VULNERáVEL". Antagonistas rotulados de modo detectável de receptores de removedores macrófagos para o diagnóstico e monitoração de diversas doenças cardiovasculares incluindo sem limitação aterosclerose, placa vulnerável, doença das artérias coronárias, doença renal, trombose, isquemia temporária devida a coágulos, derrame cerebral, enfarte do miocárdio, transplante de um órgão, insuficiência de órgão e hipercolesterolemia.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US27095401P | 2001-02-23 | 2001-02-23 | |
PCT/US2002/005156 WO2002067761A2 (en) | 2001-02-23 | 2002-02-22 | Labeled macrophage scavenger receptor antagonists for imaging atherosclerosis and vulnerable plaque |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0207521A true BR0207521A (pt) | 2004-06-01 |
Family
ID=23033552
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0207521-0A BR0207521A (pt) | 2001-02-23 | 2002-02-22 | Antagonistas rotulados de receptores de removedores macrófagos para a geração de imagens de aterosclerose e placa vulnerável |
Country Status (12)
Country | Link |
---|---|
US (2) | US6869590B2 (pt) |
EP (1) | EP1377321A4 (pt) |
JP (1) | JP2004530654A (pt) |
CN (1) | CN1622832A (pt) |
AU (1) | AU2002254000A1 (pt) |
BR (1) | BR0207521A (pt) |
CA (1) | CA2438174A1 (pt) |
CZ (1) | CZ20032564A3 (pt) |
HU (1) | HUP0400027A3 (pt) |
IL (1) | IL157444A0 (pt) |
MX (1) | MXPA03007534A (pt) |
WO (1) | WO2002067761A2 (pt) |
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KR20040015234A (ko) * | 2001-05-02 | 2004-02-18 | 펄듀 리서치 파운데이션 | 대식세포 매개된 질환의 치료와 진단 |
JP2005502618A (ja) * | 2001-06-04 | 2005-01-27 | ザ・ジェネラル・ホスピタル・コーポレイション | 光力学的化合物を用いて脆弱なプラークを検出および治療する方法 |
CA2461836A1 (en) * | 2001-10-16 | 2003-04-24 | Epix Medical, Inc. | Detection and treatment of intravascular lesions |
US8043603B2 (en) | 2002-02-07 | 2011-10-25 | Endocyte, Inc. | Folate targeted enhanced tumor and folate receptor positive tissue optical imaging technology |
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US7018614B2 (en) * | 2002-11-05 | 2006-03-28 | Eastern Isotopes, Inc. | Stabilization of radiopharmaceuticals labeled with 18-F |
WO2004043497A1 (en) | 2002-11-05 | 2004-05-27 | Ion Beam Applications S.A. | Stabilzation of radiopharmceuticals labeled with 18-f |
GB0228490D0 (en) * | 2002-12-06 | 2003-01-08 | Amersham Plc | Novel imaging compounds |
US7153299B1 (en) | 2003-02-24 | 2006-12-26 | Maxwell Sensors Inc. | Optical apparatus for detecting and treating vulnerable plaque |
US7297154B2 (en) | 2003-02-24 | 2007-11-20 | Maxwell Sensors Inc. | Optical apparatus for detecting and treating vulnerable plaque |
US7803352B2 (en) * | 2003-03-07 | 2010-09-28 | John Steele Fisher | Method for continuous visualization of a blood clot or plaque in body lumen |
ATE412897T1 (de) | 2003-05-30 | 2008-11-15 | Purdue Research Foundation | Diagnoseverfahren für atherosklerose |
US7829597B2 (en) | 2003-10-03 | 2010-11-09 | Merck, Sharp & Dohme, Inc. | Benzylether and benzylamino beta-secretase inhibitors for the treatment of alzheimer's disease |
EP1602931A1 (en) * | 2004-06-03 | 2005-12-07 | Universiteit Leiden | SR-A antagonists |
US20080206150A1 (en) * | 2004-06-25 | 2008-08-28 | The Regents Of The University Of California | Nanoparticles for Imaging Atherosclerotic Plaque |
US7575738B2 (en) | 2004-08-13 | 2009-08-18 | General Electric Company | Heat shock protein as a targeting agent for endothelium-specific in vivo transduction |
CA2592302C (en) * | 2004-12-23 | 2013-10-29 | Purdue Research Foundation | Positron emission tomography imaging method |
JP5175723B2 (ja) | 2005-07-05 | 2013-04-03 | パーデュー・リサーチ・ファウンデーション | 単球介在性疾患を治療するための組成物の調製 |
US7874975B2 (en) * | 2005-07-20 | 2011-01-25 | Clear Vascular, Inc. | Methods and compositions for treating luminal inflammatory disease |
WO2007038346A2 (en) | 2005-09-23 | 2007-04-05 | Purdue Research Foundation | Multiphoton in vivo flow cytometry method and device |
US20070196282A1 (en) * | 2006-02-21 | 2007-08-23 | Siemens Medical Solutions Usa, Inc. | Medical diagnostic ultrasound with temperature-dependent contrast agents |
EP2087337A4 (en) | 2006-11-03 | 2010-09-08 | Purdue Research Foundation | METHOD AND DEVICE FOR EX-VIVO FLOW CYTOMETRY |
EP2109466B1 (en) | 2007-02-07 | 2014-11-12 | Purdue Research Foundation | Positron emission tomography imaging method |
WO2008148001A2 (en) * | 2007-05-25 | 2008-12-04 | Purdue Research Foundation | Method of imaging localized infections |
JP2011503239A (ja) * | 2007-11-07 | 2011-01-27 | ジーイー・ヘルスケア・ベスローテン・ヴェンノーツハップ | 放射性医薬品の安定化 |
US20090287120A1 (en) | 2007-12-18 | 2009-11-19 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Circulatory monitoring systems and methods |
US8636670B2 (en) | 2008-05-13 | 2014-01-28 | The Invention Science Fund I, Llc | Circulatory monitoring systems and methods |
US9717896B2 (en) | 2007-12-18 | 2017-08-01 | Gearbox, Llc | Treatment indications informed by a priori implant information |
CN101970015B (zh) | 2008-01-08 | 2014-05-07 | 兰休斯医疗成像公司 | 作为显像剂的n-烷氧基酰胺共轭物 |
US20100178245A1 (en) * | 2009-01-13 | 2010-07-15 | Arnsdorf Morton F | Biocompatible Microbubbles to Deliver Radioactive Compounds to Tumors, Atherosclerotic Plaques, Joints and Other Targeted Sites |
US8877157B2 (en) | 2009-07-08 | 2014-11-04 | Lantheus Medical Imaging, Inc. | N-alkoxyamide conjugates as imaging agents |
WO2013070471A1 (en) | 2011-11-11 | 2013-05-16 | Lantheus Medical Imaging, Inc. | Evaluation of presence of and vulnerability to atrial fibrillation and other indications using matrix metalloproteinase-based imaging |
DE112016001921T5 (de) | 2015-06-09 | 2018-01-11 | Cummins Filtration Ip, Inc. | System und Verfahren zur Verwendung einer reibungsarmen Kontaktdichtung für einen rotierenden Tropfenabscheider |
JP7203824B2 (ja) * | 2017-08-15 | 2023-01-13 | コーニンクレッカ フィリップス エヌ ヴェ | 周波数調整可能な管腔内超音波装置 |
WO2019118592A1 (en) * | 2017-12-12 | 2019-06-20 | Massachusetts Institute Of Technology | Cell-permeable imaging sensors and uses thereof |
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-
2002
- 2002-02-22 CN CNA028087704A patent/CN1622832A/zh active Pending
- 2002-02-22 JP JP2002567138A patent/JP2004530654A/ja active Pending
- 2002-02-22 BR BR0207521-0A patent/BR0207521A/pt not_active IP Right Cessation
- 2002-02-22 EP EP02723207A patent/EP1377321A4/en not_active Withdrawn
- 2002-02-22 CA CA002438174A patent/CA2438174A1/en not_active Abandoned
- 2002-02-22 AU AU2002254000A patent/AU2002254000A1/en not_active Abandoned
- 2002-02-22 WO PCT/US2002/005156 patent/WO2002067761A2/en active Application Filing
- 2002-02-22 CZ CZ20032564A patent/CZ20032564A3/cs unknown
- 2002-02-22 HU HU0400027A patent/HUP0400027A3/hu unknown
- 2002-02-22 IL IL15744402A patent/IL157444A0/xx unknown
- 2002-02-22 US US10/080,974 patent/US6869590B2/en not_active Expired - Fee Related
- 2002-02-22 MX MXPA03007534A patent/MXPA03007534A/es active IP Right Grant
-
2003
- 2003-08-14 US US10/641,688 patent/US6974567B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US6974567B2 (en) | 2005-12-13 |
US6869590B2 (en) | 2005-03-22 |
HUP0400027A2 (hu) | 2004-04-28 |
WO2002067761A3 (en) | 2003-02-13 |
CZ20032564A3 (cs) | 2004-09-15 |
JP2004530654A (ja) | 2004-10-07 |
CA2438174A1 (en) | 2002-09-06 |
CN1622832A (zh) | 2005-06-01 |
HUP0400027A3 (en) | 2006-01-30 |
AU2002254000A1 (en) | 2002-09-12 |
US20020127181A1 (en) | 2002-09-12 |
US20040057900A1 (en) | 2004-03-25 |
EP1377321A4 (en) | 2006-01-11 |
WO2002067761A2 (en) | 2002-09-06 |
IL157444A0 (en) | 2004-03-28 |
EP1377321A2 (en) | 2004-01-07 |
MXPA03007534A (es) | 2003-12-04 |
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Legal Events
Date | Code | Title | Description |
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B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 8A E 9A ANUIDADE(S). |
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B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2103 DE 26/04/2011. |