CN1575301A - 对雌性动物施用核酸序列 - Google Patents

对雌性动物施用核酸序列 Download PDF

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Publication number
CN1575301A
CN1575301A CNA018220088A CN01822008A CN1575301A CN 1575301 A CN1575301 A CN 1575301A CN A018220088 A CNA018220088 A CN A018220088A CN 01822008 A CN01822008 A CN 01822008A CN 1575301 A CN1575301 A CN 1575301A
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CN
China
Prior art keywords
carrier
jenny
cell
offspring
people
Prior art date
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Pending
Application number
CNA018220088A
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English (en)
Chinese (zh)
Inventor
R·J·施瓦茨
R·H·卡彭特
R·德勒吉亚-阿克里
D·R·克恩
R·G·史密斯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Baylor College of Medicine
Advisys Inc
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Baylor College of Medicine
Advisys Inc
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Publication date
Application filed by Baylor College of Medicine, Advisys Inc filed Critical Baylor College of Medicine
Publication of CN1575301A publication Critical patent/CN1575301A/zh
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00Rearing or breeding animals, not otherwise provided for; New breeds of animals
    • A01K67/027New breeds of vertebrates
    • A01K67/0271Chimeric animals, e.g. comprising exogenous cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/60Growth-hormone releasing factors (GH-RF) (Somatoliberin)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2207/00Modified animals
    • A01K2207/15Humanized animals
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00Animals characterised by purpose
    • A01K2267/02Animal zootechnically ameliorated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00Uses of viruses
    • C12N2799/02Uses of viruses as vector
    • C12N2799/021Uses of viruses as vector for the expression of a heterologous nucleic acid
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/008Vector systems having a special element relevant for transcription cell type or tissue specific enhancer/promoter combination
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/15Vector systems having a special element relevant for transcription chimeric enhancer/promoter combination
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/80Vector systems having a special element relevant for transcription from vertebrates
    • C12N2830/85Vector systems having a special element relevant for transcription from vertebrates mammalian
CNA018220088A 2000-12-12 2001-12-12 对雌性动物施用核酸序列 Pending CN1575301A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25502100P 2000-12-12 2000-12-12
US60/255,021 2000-12-12

Publications (1)

Publication Number Publication Date
CN1575301A true CN1575301A (zh) 2005-02-02

Family

ID=22966509

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA018220088A Pending CN1575301A (zh) 2000-12-12 2001-12-12 对雌性动物施用核酸序列

Country Status (10)

Country Link
EP (1) EP1364004A4 (fr)
KR (1) KR20040039187A (fr)
CN (1) CN1575301A (fr)
AR (1) AR035671A1 (fr)
AU (1) AU2002248194B2 (fr)
BR (1) BR0116472A (fr)
CA (1) CA2430921C (fr)
MX (1) MXPA03005236A (fr)
PL (1) PL366116A1 (fr)
WO (1) WO2002061037A2 (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102127545A (zh) * 2010-11-24 2011-07-20 山东农业大学 一种骨骼肌特异性ckm启动子及其应用
CN105219774A (zh) * 2015-10-10 2016-01-06 广西大学 猪胰岛素特异性表达启动子pip2及其应用
CN105617404A (zh) * 2016-01-27 2016-06-01 广州市科虎生物技术研究开发中心 Grf表达质粒在制备降低仔猪出生弱仔率的药物中的用途

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003038112A2 (fr) 2001-10-26 2003-05-08 Baylor College Of Medicine Composition et methode permettant de modifier la masse maigre et les proprietes osseuses d'un sujet
MXPA04007638A (es) 2002-02-07 2004-12-06 Baylor College Medicine Desarrollo modificado de la glandula pituitaria en productos de madres animales prenadas, tratadas con terapia de hormona liberadora de hormona del crecimiento.
AU2003249208B2 (en) 2002-07-16 2010-03-04 Vgx Pharmaceuticals, Llc Codon optimized synthetic plasmids
DE10240418A1 (de) * 2002-09-02 2004-03-11 Avontec Gmbh Formulierung zur Einschleusung von Nukleinsäuren in eukaryotische Zellen
AU2003295366B2 (en) * 2002-11-04 2011-11-24 Advisys, Inc. Synthetic muscle promoters with activities exceeding naturally occurring regulatory sequences in cardiac cells
US20040204358A1 (en) * 2003-01-28 2004-10-14 Advisys, Inc. Reducing culling in herd animals growth hormone releasing hormone (GHRH)
CN104031930B (zh) * 2014-05-30 2017-09-22 华南农业大学 一种提高母猪乳中营养及免疫物质含量的方法
DE202018105142U1 (de) * 2018-04-29 2018-10-08 Kalmarna Limited - CCS Trustees Limited Zusammensetzungen zur oralen Verabreichung zum Beeinflussen der Nachkommenschaft von Säugetieren

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2622455B1 (fr) * 1987-11-04 1991-07-12 Agronomique Inst Nat Rech Application du facteur de stimulation de la secretion de l'hormone de croissance humaine, de ses fragments actifs et des analogues correspondants, pour augmenter la production laitiere et le poids des nouveau-nes chez les mammiferes
ZA914983B (en) * 1990-06-29 1992-03-25 Hoffmann La Roche His-grf-analogs
US6165755A (en) * 1997-01-23 2000-12-26 University Of Victoria Innovation And Development Corporation Chicken neuropeptide gene useful for improved poultry production
AU8589998A (en) * 1997-07-24 1999-02-16 Valentis, Inc. Ghrh expression system and methods of use
EP1204321B1 (fr) * 1999-07-26 2005-11-09 Baylor College Of Medicine Analogue superactif de la somatostatine porcine

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102127545A (zh) * 2010-11-24 2011-07-20 山东农业大学 一种骨骼肌特异性ckm启动子及其应用
CN105219774A (zh) * 2015-10-10 2016-01-06 广西大学 猪胰岛素特异性表达启动子pip2及其应用
CN105617404A (zh) * 2016-01-27 2016-06-01 广州市科虎生物技术研究开发中心 Grf表达质粒在制备降低仔猪出生弱仔率的药物中的用途

Also Published As

Publication number Publication date
EP1364004A4 (fr) 2005-11-09
AU2002248194B2 (en) 2007-04-05
PL366116A1 (en) 2005-01-24
WO2002061037A2 (fr) 2002-08-08
EP1364004A2 (fr) 2003-11-26
BR0116472A (pt) 2005-04-05
WO2002061037B1 (fr) 2004-01-15
AR035671A1 (es) 2004-06-23
CA2430921C (fr) 2016-06-07
MXPA03005236A (es) 2005-04-08
WO2002061037A3 (fr) 2003-10-02
KR20040039187A (ko) 2004-05-10
CA2430921A1 (fr) 2002-08-08

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