CN1571680A - Pacap组合物及用于肿瘤成像与治疗的方法 - Google Patents

Pacap组合物及用于肿瘤成像与治疗的方法 Download PDF

Info

Publication number
CN1571680A
CN1571680A CNA028206819A CN02820681A CN1571680A CN 1571680 A CN1571680 A CN 1571680A CN A028206819 A CNA028206819 A CN A028206819A CN 02820681 A CN02820681 A CN 02820681A CN 1571680 A CN1571680 A CN 1571680A
Authority
CN
China
Prior art keywords
carcinoma
pacap
cancer
tumor
testee
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA028206819A
Other languages
English (en)
Chinese (zh)
Inventor
马休卡·马休·L·塔可尔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Thomas Jefferson University
Original Assignee
Thomas Jefferson University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomas Jefferson University filed Critical Thomas Jefferson University
Publication of CN1571680A publication Critical patent/CN1571680A/zh
Pending legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CNA028206819A 2001-10-19 2002-10-21 Pacap组合物及用于肿瘤成像与治疗的方法 Pending CN1571680A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34451101P 2001-10-19 2001-10-19
US60/344,511 2001-10-19

Publications (1)

Publication Number Publication Date
CN1571680A true CN1571680A (zh) 2005-01-26

Family

ID=23350835

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA028206819A Pending CN1571680A (zh) 2001-10-19 2002-10-21 Pacap组合物及用于肿瘤成像与治疗的方法

Country Status (9)

Country Link
US (1) US6855308B2 (enExample)
EP (1) EP1441773A1 (enExample)
JP (1) JP2005514335A (enExample)
KR (1) KR20040055784A (enExample)
CN (1) CN1571680A (enExample)
CA (1) CA2464002C (enExample)
IL (1) IL161332A0 (enExample)
RU (1) RU2004115104A (enExample)
WO (1) WO2003033030A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050009739A1 (en) * 2002-02-14 2005-01-13 Wei Wang Formulation strategies in stabilizing peptides in organic solvents and in dried states
US9006181B2 (en) 2004-07-21 2015-04-14 The Administrators Of The Tulane Educational Fund Treatment of renal dysfunction and multiple myeloma using PACAP compounds
WO2011013703A1 (ja) * 2009-07-31 2011-02-03 独立行政法人理化学研究所 膵臓内分泌細胞用指示薬、及びその利用
JP5908406B2 (ja) 2009-11-02 2016-04-26 ジ アドミニストレーターズ オブ ザ トゥレーン エデュケーショナル ファンド 下垂体アデニル酸シクラーゼ活性化ポリペプチド（ｐａｃａｐ）の類似体およびその使用方法
ES2667119T3 (es) * 2010-06-24 2018-05-09 Genomictree, Inc. Vector recombinante para suprimir la proliferación de células del papilomavirus humano que incluyen el gen del polipéptido activador de la adenilato ciclasa 1 (hipófisis) y composición farmacéutica para tratar el papilomavirus humano
KR20150143440A (ko) * 2013-02-15 2015-12-23 토마스 제퍼슨 유니버시티 떨어져 나가거나 순환 중인 종양세포를 생물학적 유액 내에서 탐지하는 방법
CA2901231C (en) * 2013-02-15 2020-06-23 Thomas Jefferson University Kit comprising lyophilized compositions for tumor imaging
JP2016528299A (ja) * 2013-08-22 2016-09-15 ロバート・ドイルＲｏｂｅｒｔ ＤＯＹＬＥ ビタミンｂ１２および内因子を含む組成物およびその使用方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5997844A (en) * 1991-02-08 1999-12-07 Diatide, Inc. Technetium-99m labeled peptides for imaging
US5849261A (en) * 1991-02-08 1998-12-15 Diatide, Inc. Radiolabeled vasoactive intestinal peptides for diagnosis and therapy
US5965107A (en) * 1992-03-13 1999-10-12 Diatide, Inc. Technetium-99m labeled peptides for imaging
US6107459A (en) * 1991-02-08 2000-08-22 Diatide, Inc. Technetium-99m labeled peptides for diagnostic imaging
US5508020A (en) * 1992-06-05 1996-04-16 Diatech, Inc. Technetium-99M labeled peptides for imaging
US6165755A (en) * 1997-01-23 2000-12-26 University Of Victoria Innovation And Development Corporation Chicken neuropeptide gene useful for improved poultry production
US6395255B1 (en) * 1998-06-15 2002-05-28 Thomas Jefferson University Radiolabeled vasoactive intestinal peptide analogs for imaging and therapy

Also Published As

Publication number Publication date
EP1441773A1 (en) 2004-08-04
KR20040055784A (ko) 2004-06-26
CA2464002A1 (en) 2003-04-24
US20030129133A1 (en) 2003-07-10
WO2003033030A1 (en) 2003-04-24
CA2464002C (en) 2011-06-28
JP2005514335A (ja) 2005-05-19
US6855308B2 (en) 2005-02-15
RU2004115104A (ru) 2005-02-20
IL161332A0 (en) 2004-09-27

Similar Documents

Publication Publication Date Title
CN1093424C (zh) 含单胺、联氨、硫羟基的金属螯合剂
JP7282792B2 (ja) 前立腺特異的膜抗原発現癌の診断または治療のための新規放射性金属結合化合物
CN1078480C (zh) 生长激素抑制素结合肽－金属络合物
JP5295967B2 (ja) 受容体（ｓｓｔｒ２）選択的ソマトスタチンアンタゴニスト
US20240350681A1 (en) Radiolabeled melanocortin 1 receptor-specific alpha-melanocyte-stimulating hormone analogues for imaging or therapy
CN1154072A (zh) 用于成象的锝-99m标记的肽
CN1181096C (zh) 环六肽抑生长素类似物
US12612343B2 (en) PSMA binder and use thereof
CN1822861A (zh) 稳定的放射性药物组合物及制备方法
CN1622832A (zh) 用于动脉粥样硬化和易病变性斑块成像的标记的巨噬细胞清除剂受体拮抗剂
CN1622830A (zh) 肽基化合物
CN1503680A (zh) 用于金属放射性药物的抗坏血酸类似物
JP7838149B2 (ja) 癌のイメージングおよび治療のための修飾されたｇｒｐｒアンタゴニストペプチド
CN104780944B (zh) 用于癌症和其它疾病的医学成像的靶向缓激肽受体b1的组合物
CN101065152A (zh) 靶向尿激酶纤溶酶原激活物受体的造影剂
EP4619043A1 (en) Fibroblast activation protein targeted compounds and use thereof
CN1152881A (zh) 锝-99m标记的成像剂
CN1852742A (zh) 具有抑制生长激素释放活性的促生长素抑制素类似物
CN105377287A (zh) 用于肿瘤成像的试剂盒
CA2464002C (en) Pacap compositions and methods for tumor imaging and therapy
EP0584256B1 (en) Compounds and pharmaceutical compositions for detecting and localizing tissues having neurokinine 1 receptors
CN1708322A (zh) 锝络合物和靶标部分的共轭体及其在mri诊断中的用途
CN1684973A (zh) 结合白细胞的化合物以及含有标记状态的该化合物作为有效成分的药用组合物
CN101039702A (zh) 作为靶向试剂用于内皮－特异性体内转导的热激蛋白
CN1901941A (zh) 血管紧张素ii与成像部分的缀合物

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication