CN1543359A - 可生物利用的口服剂型醋氯芬酸组合物及其制备方法 - Google Patents

可生物利用的口服剂型醋氯芬酸组合物及其制备方法 Download PDF

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Publication number
CN1543359A
CN1543359A CNA028134176A CN02813417A CN1543359A CN 1543359 A CN1543359 A CN 1543359A CN A028134176 A CNA028134176 A CN A028134176A CN 02813417 A CN02813417 A CN 02813417A CN 1543359 A CN1543359 A CN 1543359A
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CN
China
Prior art keywords
aceclofenac
pharmaceutical preparation
preparation
described pharmaceutical
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA028134176A
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English (en)
Chinese (zh)
Inventor
���
李凡珍
李东源
金泰完
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PHARM TECH RES Inc
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PHARM TECH RES Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PHARM TECH RES Inc filed Critical PHARM TECH RES Inc
Publication of CN1543359A publication Critical patent/CN1543359A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CNA028134176A 2001-07-03 2002-06-25 可生物利用的口服剂型醋氯芬酸组合物及其制备方法 Pending CN1543359A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR2001/39387 2001-07-03
KR10-2001-0039387A KR100425226B1 (ko) 2001-07-03 2001-07-03 아세클로페낙을 함유하는 경제적인 경구용 제제의 조성 및제법

Publications (1)

Publication Number Publication Date
CN1543359A true CN1543359A (zh) 2004-11-03

Family

ID=19711694

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA028134176A Pending CN1543359A (zh) 2001-07-03 2002-06-25 可生物利用的口服剂型醋氯芬酸组合物及其制备方法

Country Status (6)

Country Link
US (1) US20040180961A1 (https=)
EP (1) EP1409023A1 (https=)
JP (1) JP2004536108A (https=)
KR (1) KR100425226B1 (https=)
CN (1) CN1543359A (https=)
WO (1) WO2003004060A1 (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1301709C (zh) * 2005-02-17 2007-02-28 西安东盛集团有限公司 一种含醋氯芬酸的皮肤用贴剂
CN102917696A (zh) * 2010-06-01 2013-02-06 韩国联合制药株式会社 在每日施用一次时提供最佳药理学临床效应的醋氯芬酸缓释制剂
CN102307575B (zh) * 2009-02-04 2013-02-13 韩国联合制药株式会社 含醋氯芬酸的控释口服药制剂及其制造方法

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* Cited by examiner, † Cited by third party
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ATE395044T1 (de) 2002-02-01 2008-05-15 Pfizer Prod Inc Pharmazeutische zusammensetzungen amorpher dispersionen von wirkstoffen und lipophiler mikrophasenbildender materialien
EP1920766B1 (en) * 2002-02-01 2017-08-23 Bend Research, Inc Pharmaceutical compositions of amorphous dispersions of drugs and lipophilic microphase-forming materials
JP2007501218A (ja) 2003-08-04 2007-01-25 ファイザー・プロダクツ・インク 非晶質薬物の吸着物および親油性ミクロ相形成物質の医薬組成物
US20060019933A1 (en) * 2004-07-22 2006-01-26 David Boardman Process for preparing stabilized vitamin D
ATE476962T1 (de) * 2004-11-22 2010-08-15 Venus Remedies Ltd Nichtwässrige flüssige parenterale aceclofenac- formulierung
KR100806541B1 (ko) * 2005-05-11 2008-02-26 한국유나이티드제약 주식회사 아세클로페낙을 함유하는 제어 방출성 제제
GB0613925D0 (en) * 2006-07-13 2006-08-23 Unilever Plc Improvements relating to nanodispersions
US8685457B2 (en) * 2007-06-06 2014-04-01 Basf Se Pharmaceutical formulation for the production of rapidly disintegrating tablets
KR100911517B1 (ko) * 2007-08-31 2009-08-10 주식회사 드림파마 신규한 서방출형 아세클로페낙 제제 조성물 및 그의제조방법
KR101003204B1 (ko) * 2008-02-14 2010-12-21 메콕스큐어메드 주식회사 약물 전달용 고형 지질 나노입자, 그 제조방법, 및 그나노입자를 포함하는 주사제
AR071375A1 (es) * 2008-04-22 2010-06-16 Solvay Pharm Gmbh Formulaciones para ingredientes farmaceuticos activos de permeabilidad deficiente, proceso de preparacion y producto
US20090281136A1 (en) * 2008-05-08 2009-11-12 Sandeep Mhetre Prasugrel pharmaceutical formulations
KR100986531B1 (ko) * 2008-07-18 2010-10-07 한국콜마 주식회사 액상의 아세클로페낙을 함유하는 캡슐제
US20100120906A1 (en) * 2008-07-18 2010-05-13 Valeant Pharmaceuticals International Modified release formulation and methods of use
KR101018894B1 (ko) * 2008-08-27 2011-03-04 근화제약주식회사 체내 흡수가 증진된 탈니플루메이트 함유 서방정
US20110229527A1 (en) * 2008-11-20 2011-09-22 Nandu Deorkar Directly compressible high functionality granular dibasic calcium phosphate based co-processed excipient
RU2686183C2 (ru) * 2014-01-21 2019-04-24 БиПиЭсАй ХОЛДИНГЗ, ЭлЭлСи Пленочные покрытия быстрого высвобождения, содержащие среднецепочечные глицериды, и покрытые ими субстраты
TWI586379B (zh) * 2015-06-29 2017-06-11 永信藥品工業股份有限公司 一種製作難溶藥物固體劑型的方法
KR102840190B1 (ko) * 2022-04-19 2025-07-29 (의) 삼성의료재단 생리활성물질 전달체

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5756450A (en) * 1987-09-15 1998-05-26 Novartis Corporation Water soluble monoesters as solubilisers for pharmacologically active compounds and pharmaceutical excipients and novel cyclosporin galenic forms
JPH08157362A (ja) * 1994-12-06 1996-06-18 Sankyo Co Ltd 油性物質含有固形製剤の製法
KR100239799B1 (ko) * 1995-01-21 2000-02-01 손경식 경구투여용 사이클로스포린 에이 고체미셀분산체, 이의 제조 방법 및 고형제제
SE9600070D0 (sv) * 1996-01-08 1996-01-08 Astra Ab New oral pharmaceutical dosage forms
KR100320361B1 (ko) * 1998-05-08 2002-05-13 류덕희 비스테로이드성소염진통약물의마이크로에멀젼외용제
KR100336090B1 (ko) * 1998-06-27 2002-05-27 윤승원 오일, 지방산 또는 이들의 혼합물을 함유한 난용성 약물의 고형분산제제
GB9908014D0 (en) * 1999-04-08 1999-06-02 Scherer Corp R P Pharmaceutical compositions

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1301709C (zh) * 2005-02-17 2007-02-28 西安东盛集团有限公司 一种含醋氯芬酸的皮肤用贴剂
CN102307575B (zh) * 2009-02-04 2013-02-13 韩国联合制药株式会社 含醋氯芬酸的控释口服药制剂及其制造方法
CN102917696A (zh) * 2010-06-01 2013-02-06 韩国联合制药株式会社 在每日施用一次时提供最佳药理学临床效应的醋氯芬酸缓释制剂

Also Published As

Publication number Publication date
JP2004536108A (ja) 2004-12-02
US20040180961A1 (en) 2004-09-16
EP1409023A1 (en) 2004-04-21
KR20030003500A (ko) 2003-01-10
WO2003004060A1 (en) 2003-01-16
KR100425226B1 (ko) 2004-03-30

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