CN1511039A - 降低血浆葡萄糖的方法 - Google Patents

降低血浆葡萄糖的方法 Download PDF

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Publication number
CN1511039A
CN1511039A CNA028099958A CN02809995A CN1511039A CN 1511039 A CN1511039 A CN 1511039A CN A028099958 A CNA028099958 A CN A028099958A CN 02809995 A CN02809995 A CN 02809995A CN 1511039 A CN1511039 A CN 1511039A
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CN
China
Prior art keywords
gram
solid
amine polymers
poly
group
Prior art date
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Pending
Application number
CNA028099958A
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English (en)
Chinese (zh)
Inventor
ʷ���ġ�K������
史蒂文·K·勃克
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Genzyme Corp
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Genzyme Corp
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Publication date
Application filed by Genzyme Corp filed Critical Genzyme Corp
Publication of CN1511039A publication Critical patent/CN1511039A/zh
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/785Polymers containing nitrogen
    • A61K31/787Polymers containing nitrogen containing heterocyclic rings having nitrogen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/785Polymers containing nitrogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

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  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CNA028099958A 2001-04-18 2002-04-10 降低血浆葡萄糖的方法 Pending CN1511039A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US28444501P 2001-04-18 2001-04-18
US60/284,445 2001-04-18
US30556401P 2001-07-13 2001-07-13
US60/305,564 2001-07-13

Publications (1)

Publication Number Publication Date
CN1511039A true CN1511039A (zh) 2004-07-07

Family

ID=26962623

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA028099958A Pending CN1511039A (zh) 2001-04-18 2002-04-10 降低血浆葡萄糖的方法

Country Status (17)

Country Link
US (2) US7229613B2 (enExample)
EP (1) EP1392331B1 (enExample)
JP (2) JP4499363B2 (enExample)
KR (1) KR20040018358A (enExample)
CN (1) CN1511039A (enExample)
AT (1) ATE390927T1 (enExample)
AU (1) AU2002257145B2 (enExample)
BR (1) BRPI0209134B8 (enExample)
CA (1) CA2444046C (enExample)
CY (1) CY1119486T1 (enExample)
DE (1) DE60225908T2 (enExample)
DK (2) DK1392331T3 (enExample)
ES (2) ES2637020T3 (enExample)
MX (1) MXPA03009568A (enExample)
NZ (1) NZ528831A (enExample)
PT (1) PT1923064T (enExample)
WO (1) WO2002085377A1 (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105188718A (zh) * 2013-03-15 2015-12-23 建新公司 晚期糖化终产物(age)前体的螯合剂
CN107250189A (zh) * 2014-12-18 2017-10-13 建新公司 用于治疗2型糖尿病的交联聚二烯丙胺共聚物
WO2023023939A1 (en) * 2021-08-24 2023-03-02 Waterstone Pharmaceuticals (Wuhan) Co., Ltd. Polymers, compositions and methods for treating hyperuricemia
WO2023023938A1 (en) * 2021-08-24 2023-03-02 Waterstone Pharmaceuticals (Wuhan) Co., Ltd. Polymers, compositions and methods for treating hyperuricemia

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US6733780B1 (en) 1999-10-19 2004-05-11 Genzyme Corporation Direct compression polymer tablet core
ES2637020T3 (es) * 2001-04-18 2017-10-10 Genzyme Corporation Uso de polímero de amina para reducir la glucosa sérica
AU2003282867A1 (en) * 2002-10-22 2004-05-13 Genzyme Corporation Amine polymers for promoting bone formation
US7608674B2 (en) * 2003-11-03 2009-10-27 Ilypsa, Inc. Pharmaceutical compositions comprising cross-linked small molecule amine polymers
US7449605B2 (en) * 2003-11-03 2008-11-11 Ilypsa, Inc. Crosslinked amine polymers
US7767768B2 (en) * 2003-11-03 2010-08-03 Ilypsa, Inc. Crosslinked amine polymers
US7335795B2 (en) * 2004-03-22 2008-02-26 Ilypsa, Inc. Crosslinked amine polymers
US7385012B2 (en) * 2003-11-03 2008-06-10 Ilypsa, Inc. Polyamine polymers
US7459502B2 (en) * 2003-11-03 2008-12-02 Ilypsa, Inc. Pharmaceutical compositions comprising crosslinked polyamine polymers
ES2397159T3 (es) * 2004-03-26 2013-03-05 Mitsubishi Tanabe Pharma Corporation Agente mejorador de la resistencia a insulina
US7985418B2 (en) 2004-11-01 2011-07-26 Genzyme Corporation Aliphatic amine polymer salts for tableting
WO2006072054A1 (en) * 2004-12-30 2006-07-06 Genzyme Corporation Zinc-containing treatments for hyperphosphatemia
JP2009507019A (ja) * 2005-09-02 2009-02-19 ジェンザイム・コーポレーション リン酸塩を除去する方法およびそれに使用される重合体
KR101547925B1 (ko) 2005-09-15 2015-08-27 젠자임 코포레이션 아민 중합체에 대한 샤셋 제형
WO2007056405A2 (en) * 2005-11-08 2007-05-18 Genzyme Corporation Magnesium-containing polymers for the treatment of hyperphosphatemia
EP2043627A2 (en) * 2006-07-05 2009-04-08 Genzyme Corporation Iron(ii)-containing treatments for hyperphosphatemia
US7964182B2 (en) * 2006-09-01 2011-06-21 USV, Ltd Pharmaceutical compositions comprising phosphate-binding polymer
BRPI0717008A2 (pt) * 2006-09-01 2014-01-21 Usv Ltd Processo para o preparo de cloridrato de sevelamer e formulação do mesmo
WO2008042222A2 (en) 2006-09-29 2008-04-10 Genzyme Corporation Amide dendrimer compositions
WO2008076242A1 (en) 2006-12-14 2008-06-26 Genzyme Corporation Amido-amine polymer compositions
EP2361171A4 (en) * 2008-09-15 2014-11-05 Shasun Chemicals And Drugs Ltd PROCESS FOR PREPARING NETWORKED POLYMERS IN A NON-AQUEOUS SOLUTION
AU2010209293A1 (en) * 2009-01-22 2011-09-08 Usv Limited Pharmaceutical compositions comprising phosphate-binding polymer
US9566299B2 (en) 2013-02-08 2017-02-14 Wockhardt Limited Oral pharmaceutical composition of aliphatic amine polymer or salts thereof
EP3164155B1 (en) 2014-06-13 2022-02-09 United Therapeutics Corporation Treprostinil formulations
WO2018124264A1 (ja) 2016-12-28 2018-07-05 富士フイルム株式会社 窒素原子含有ポリマー又はその塩の乳化液、その製造方法、及び粒子の製造方法
JP6992084B2 (ja) 2017-10-16 2022-01-13 富士フイルム株式会社 高リン血症治療剤

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US4528847A (en) * 1983-10-04 1985-07-16 D. Halmi And Associates, Inc. Flow metering device with recessed pressure taps
JPS6090243A (ja) 1983-10-25 1985-05-21 Nitto Boseki Co Ltd 小球状モノアリルアミン橋かけ重合体の製造方法
US4528347A (en) 1983-11-10 1985-07-09 501 Nitto Boseki, Co. Ltd Process for producing polymers of monoallylamine
US5468727A (en) * 1990-12-13 1995-11-21 Board Of Regents, The University Of Texas System Methods of normalizing metabolic parameters in diabetics
JP3507523B2 (ja) 1993-05-12 2004-03-15 積水化学工業株式会社 糖質吸収抑制剤
US5487888A (en) 1993-05-20 1996-01-30 Geltex, Inc. Iron-binding polymers for oral administration
US5607669A (en) 1994-06-10 1997-03-04 Geltex Pharmaceuticals, Inc. Amine polymer sequestrant and method of cholesterol depletion
US5624963A (en) 1993-06-02 1997-04-29 Geltex Pharmaceuticals, Inc. Process for removing bile salts from a patient and compositions therefor
US5900475A (en) 1994-06-10 1999-05-04 Geltex Pharmaceuticals, Inc. Hydrophobic sequestrant for cholesterol depletion
US5618530A (en) 1994-06-10 1997-04-08 Geltex Pharmaceuticals, Inc. Hydrophobic amine polymer sequestrant and method of cholesterol depletion
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US5667775A (en) 1993-08-11 1997-09-16 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
US5496545A (en) * 1993-08-11 1996-03-05 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
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JP4156684B2 (ja) * 1996-03-05 2008-09-24 三菱化学株式会社 高リン血症予防および/または治療剤
US6203785B1 (en) 1996-12-30 2001-03-20 Geltex Pharmaceuticals, Inc. Poly(diallylamine)-based bile acid sequestrants
US5925379A (en) 1997-03-27 1999-07-20 Geltex Pharmaceuticals, Inc. Interpenetrating polymer networks for sequestration of bile acids
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FR2766195A1 (fr) 1997-07-21 1999-01-22 Transgene Sa Polymeres cationiques, complexes associant lesdits polymeres cationiques et des substances therapeutiquement actives comprenant au moins une charges negative, notamment des acides nucleiques, et leur utilisation en therapie genique
US6083497A (en) 1997-11-05 2000-07-04 Geltex Pharmaceuticals, Inc. Method for treating hypercholesterolemia with unsubstituted polydiallylamine polymers
US6726905B1 (en) 1997-11-05 2004-04-27 Genzyme Corporation Poly (diallylamines)-based phosphate binders
US5985938A (en) 1997-11-05 1999-11-16 Geltex Pharmaceuticals, Inc. Method for reducing oxalate
WO1999040990A1 (en) 1998-02-17 1999-08-19 University Of Maryland Anion binding polymers and the use thereof
EP1340510A1 (en) * 1998-12-23 2003-09-03 G.D. Searle LLC. Combinations of cholesteryl ester transfer protein inhibitors and bile acid sequestering agents for cardiovascular indications
AU7856200A (en) * 1999-10-07 2001-05-10 University Of Maryland Sugar binding polymers and the use thereof
TWI241195B (en) * 2000-04-10 2005-10-11 Shionogi & Co Preventive agent for bile acidic diarrhea
ES2637020T3 (es) * 2001-04-18 2017-10-10 Genzyme Corporation Uso de polímero de amina para reducir la glucosa sérica
US20020198202A1 (en) 2001-06-07 2002-12-26 Wyeth Combination of a PTPase inhibitor and an antilipemic agent

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105188718A (zh) * 2013-03-15 2015-12-23 建新公司 晚期糖化终产物(age)前体的螯合剂
CN107250189A (zh) * 2014-12-18 2017-10-13 建新公司 用于治疗2型糖尿病的交联聚二烯丙胺共聚物
WO2023023939A1 (en) * 2021-08-24 2023-03-02 Waterstone Pharmaceuticals (Wuhan) Co., Ltd. Polymers, compositions and methods for treating hyperuricemia
WO2023023938A1 (en) * 2021-08-24 2023-03-02 Waterstone Pharmaceuticals (Wuhan) Co., Ltd. Polymers, compositions and methods for treating hyperuricemia
US12478638B2 (en) 2021-08-24 2025-11-25 Waterstone Pharmaceuticals (Wuhan) Co., Ltd. Polymers, compositions and methods for treating hyperuricemia

Also Published As

Publication number Publication date
CA2444046A1 (en) 2002-10-31
DE60225908T2 (de) 2009-05-14
ES2304437T3 (es) 2008-10-16
WO2002085377A8 (en) 2002-11-28
JP4499363B2 (ja) 2010-07-07
ES2637020T3 (es) 2017-10-10
BRPI0209134B1 (pt) 2019-08-27
US20020187121A1 (en) 2002-12-12
KR20040018358A (ko) 2004-03-03
MXPA03009568A (es) 2004-02-12
US20070286841A1 (en) 2007-12-13
PT1923064T (pt) 2017-08-23
JP2004535384A (ja) 2004-11-25
DK1392331T3 (da) 2008-06-23
US7229613B2 (en) 2007-06-12
JP2010090172A (ja) 2010-04-22
WO2002085377A1 (en) 2002-10-31
BR0209134A (pt) 2004-06-15
NZ528831A (en) 2005-07-29
ATE390927T1 (de) 2008-04-15
BRPI0209134B8 (pt) 2021-05-25
DE60225908D1 (de) 2008-05-15
DK1923064T3 (en) 2017-10-02
EP1392331A1 (en) 2004-03-03
EP1392331B1 (en) 2008-04-02
AU2002257145B2 (en) 2005-06-02
CA2444046C (en) 2011-06-07
CY1119486T1 (el) 2018-03-07

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C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication