CN1495275A - 肿瘤诊断组合物 - Google Patents
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Abstract
一种癌症诊断组合物,通过检测从两组基因中筛选出来的组合物中每种基因的差异性调节(相对于同一基因在正常组织中的表达)来诊断癌症。本发明的另一个方面是提供基因表达组合物和应用本发明方法的试剂盒。
Description
发明背景
本申请要求2002年3月29日申请的序列号为Seq ID No.60/368,667的美国临时申请的权利。
本发明涉及诊断标记组合物的选择。
目前使用一些单基因诊断标记物,如het-2-neu。然而,通过对一个特殊基因的分子诊断通常不能简单地对疾病作出诊断。经常需要多个标记物,而且基于差异基因调节,在实验中包含的这种标记的数目可能很大,甚至是数以百计的基因。理想的是将标记物分成若干几个组合物,通过使用最小数量的必须标记物获得最可靠的结果。这在包含多个步骤的分析中尤其有用,例如核酸扩增步骤。
发明概述
本发明是一种通过鉴别基因组合物中每种基因的差异调节(相对于同一基因在正常人群中的表达)来诊断癌症的方法。基因组合物的基因选自Seq IDNo.1-30,Seq ID No.32,Seq ID No.34和Seq ID No.98。在另一个实施例中,组合物的基因选自Seq ID No.32-67,Seq ID No.69和Seq ID No.98-100。
本发明另一方面提供使用本方法的基因表达组合物和试剂盒。
发明详述
本发明的方法可以与任何检测相关细胞基因表达方式的方法及任何通过蛋白质确定基因表达的方法联合使用。建立基因表达分布图的优选方法包括检测一个能够编码蛋白质或肽的基因所产生的RNA的量。这可以通过反转录酶PCR反应(RT+PCR),竞争性RT-PCR,实时RT-PCR,差异显示RT-PCR,Seq IDNo.rthern印迹分析和其它相关试验来实现。当在单个PCR反应中使用这些技术时,最好从mRNA扩增拷贝DNA(cDNA)或拷贝RNA(cRNA),并且通过微阵列分析。对本领域技术人员来说,大量不同阵列构型及其生产方法是已知的,并且在如下美国专利中描述过:5,445,934;5,532,128;5,556,752;5,242,974;5,384,261;5,405,783;5,412,087;5,424,186;5,429,807;5,436,327;5,472,672;5,527,681;5,529,756;5,545,531;5,554,501;5,561,071;5,571,639;5,593,839;5,599,695;5,624,711;5,658,734和5,700,637。这些专利并入本文作为参考。
微阵列技术允许同时检测数以千计基因的稳定状态的mRNA水平,因而对检测细胞增殖失控的启动、抑制或者调节等效应提供了一个强有力的工具。目前广泛应用的有两种微阵列技术。第一种是cDNA阵列技术,第二种是寡聚核苷酸阵列技术。尽管这些芯片在构造上存在着差别,但是它们在下游数据分析和输出信号方面基本上相同。这些分析的结果总是通过测量来自标记探针的信号强度而获得的,所述探针是用于检测样品中与微阵列已知位置核苷酸序列杂交的cDNA序列的。典型地,信号强度与cDNA的量成比例,因而同样品细胞表达的mRNA量成比例。有许多这样的技术可以获得并且是有用。优选的检测基因表达的方法可以在美国专利中找到,如Linsley等人的专利6,271002;Friend等人的专利6,218,122;Peck等人的专利6,218,114;Wang等人的专利6,004,755。上述每一项专利均并入本文作为参考。
通过比较这些强度来分析基因表达水平。最好是构建一个检测样品与对照样品中基因表达的强度的比值矩阵。例如,将患病组织中基因表达的强度与在相同类型正常组织中基因表达的强度进行比较(如比较患病的结肠组织样品与正常的结肠组织样品)。这些表达强度的比值显示检测样品和对照样品之间基因表达有成倍的变化。
被调节的基因是指那些在异常细胞中被向上或者向下调节的差别表达的基因。上调或下调是相对的概念,是指在基因表达量上检测出相对于某个基线所能检测到的差异(超过所用检测系统噪音的部分)。在本发明中,基线就是正常细胞中被测基因的表达。那么,使用同一检测方法,目的基因在异常细胞中的表达相对基线或向上调节或向下调节。
优选地,向上调节和向下调节的水平根据杂交的微阵列探针信号强度数值倍数的变化而加以区别。例如,如果1.5倍或更多的差异作为这种区别,那么患病细胞产生的信号强度要比正常细胞至少高1.5倍或者低1.5倍。
可以通过其它的方法进行区别。例如,统计学的检验方法能够发现不同样本组之间差异最显著的基因。“斯氏”T检验是一种有说服力的统计学检验,能够发现两组样本之间显著性的差异。P值越小,不同组间基因表现出差异的证据也就越令人可信。然而,由于微阵列的检测一次超过一个基因,因此可能要求一次进行好几万次的统计学检验。正因为这样,偶尔有可能会遇见小P值,可以使用Sidak校正和作随机/排列实验对此进行调整。
T检验中P值小于0.05,是基因有显著性差异的证据。经过Sidak校正后,更令人可信的证据是P值小于0.05。对于每一组中大量样本,经过随机化/排列检验后,最令人信服的有显著性差异的证据是P值小于0.05。
基因可以被分成几组,那么从各基因组中每组基因所得到的信息就可以为临床上作出诸如诊断、预后或者治疗方案的选择等相关判断提供可靠的基础。这些基因组构成了本发明的基因组合物。虽然有大量的标记物,但是经常希望使用最少数量的标记物就足以充分作出一个正确的医学判断。这既防止了延误使用那些悬而未决因需要进一步分析才能采取的治疗措施,同时又防止了对于时间和医疗资源的不合理的使用。优选的组合物是使用最少的标记物就能作出这些判断,而且适合于将这种判断确实正确的可能性最大化的疾病。这些疾病总的来说将包括灵敏度和特异性的要求。在微阵列检测技术领域内,标记组合物的灵敏度反映在患病或异常状态下相对于正常状态基因表达所表现出的倍数差异。相对于基因在其它状态下的表达,如果检测到的基因差异表达呈现出大的倍数变化,那么这种检测是灵敏的。灵敏度的另一个方面是从噪音中区分信号的能力。例如,尽管一组基因的表达显示出足够的灵敏度能够确定某一疾病状态,但是,如果一个基因所产生的信号(例如微阵列中的强度测量值)低于在所指定的背景中(例如一个临床实验室)很容易从噪音中区分出来的水平,那么这个基因应当从优选的组合物中被排除。本发明的方法中还包括这种如鉴别优选标记组合物的确定该疾病的方法。
特异性反映在基因表达信号与目的疾病基因表达的信号相关性的统计学测量值中。如果所观察到的一组基因的差异表达产生了很大的倍数改变,但是这种差异不仅是表现在所关注的疾病,而且在许多疾病中也出现(例如,多疾病状态),那么这组基因的表达分布图则是非特异性的。表示数据之间相互关系或者一致性的统计学测量值,如标准差,相关系数等,能够作为这种测量值。考虑到在一个组合物中所包含的一组基因,表达测量值中小的标准差与更高的特异性相关。表达方式相似的基因可能是由一个相同的因素共同调节的,这个因素在同一个方向上促进基因。如果这种因子对于一个样本的分类来说是充分但不是必须的,而且所有的标记物都与这个单个因素有关的话,那么这些基因将不能正确鉴别样本。多样化导致筛选尽可能少的标记物,却要覆盖尽可能多的包含在数据集中的不同的优选表达方式。
在本发明的方法中,筛选出了一组用于疾病诊断的遗传标记物。这些组标记物就是“组合物”。疾病诊断方面的应用包括检测或者鉴别疾病的状态或者被检测对象的健康状况,预测被检测对象患某种特定疾病的可能性,预测患病的病人对治疗产生反应的可能性,评估患者的预后情况(或疾病可能的进展或消退),以及预测患者对治疗所产生的效果。例如,这种方法能够用来建立组合物,该组合物用以检测被检测对象是否患有结肠癌,或者被检测对象患结肠癌的可能性,或者这样的病人对于细胞毒性药物产生令人满意疗效的可能性。
用本发明方法筛选出的组合物包含一定数量和种类的标记物,这些标记物确保获得精确和准确的检测结果,并且在构成组合物的基因数量方面是经济的。本发明的方法能够建立优选的基因表达组合物,该组合物适用于检测伴有多基因表达的任何疾病或疾病的任何状态。在本发明的范围内,一个优选的组合物涉及基因表达分布图,它根据精确度,准确性和组合物中基因的数量这三个参数中至少两个参数的预先确定的标准,对被检测对象的健康状况作出评估(基于分析所针对的疾病)。
在组合物中最优选采用能够表达mRNA的核酸序列(“基因”)。标记物在健康人中平时也可能表达,但在接受诊断的受体人体内发生异常时,标记物可能会发生更高的表达或者不那么高表达。或者,标记物仅在接受诊断的受体人体内发生异常时才发生表达。
能够通过比较作出诊断性判断的标记物的属性,特征,指示值或者测量值是本方法中使用的诊断性参数。基因表达水平的指示值是最优选的诊断性参数。这些指标包括如上面所描述的从微阵列中读出的信号强度测量值。还可以有其它的诊断性参数,如标记物甲基化相对程度的指示值。
通过使用数学/统计学值得到相互关联的诊断参数之间的差别。优选的差别是表示基因表达的平均信号读数和这些读数的方差。最优选的差别是通过使用不同组读数(例如微阵列强度测量值)之间信号比的平均值和信号比的标准差得到的。很多种这样的数学/统计学数值应用于合适的地方,例如达到设定的百分点时就反馈。
诊断参数差别之间的关系可以用来优化筛选对于诊断应用有用的标记物。这通常是通过使用线性的或者二次的程序演算法。然而,渐进式方法也可以应用或者用于补充输入数据选择或输出数据。最优选的关系是均方差的关系,HarryM.Markowitz在Mean-Variance Analysis in Porfolio Choice ang Capital Markets(Frank J.Fabozzi Associates,New Hope,2000,ISBN:1-883249-75-9)书中描述了这种关系,将该书并入本文作为参考。在选择哪些股票作为金融投资组合物的背景下最容易理解这种关系。这是这种关系产生和解释的背景。
那些渴望优化股票组合方案的投资者能够从大量可能的股票中进行选择,每一种股票都有其以往的回报率和风险因素。均方差的方法通过严格使用线性或二次程序演算法来确定出所有可能的方案,这些方案将指定期望回报水平下的风险最小化;将指定风险水平下(如计算方差或标准差)的预期回报值最大化。当计算出预期回报的标准差后,能够产生高效率的股票组合物的边界就产生了。依据此高效边界来选择股票,就会产生在回报和风险方面多样化的优选股票组合方案。
当均方差关系用于本发明的方法中时,微阵列的信号强度和标准差这两个诊断参数替代了在选择金融投资组合方案中所使用的回报和风险因素。最优选的是,当应用均方差关系时,要应用一个商业上的计算机软件,例如“WagnerAssociates Mean-Variance Optimization Application”,在整个说明书中称作“Wagner软件”。这个软件使用来自“Wagner Associates Mean-VarianceOptimization Library”中的功能来确定高效率边界和在Markowitz意义上的优选组合物。由于上述功能是为金融方面的应用而设计的,因此可能必须对输入的数据进行预处理以使数据能够符合软件的要求。例如,当Wagner软件与微阵列强度测量值结合使用时,要使用以下的数据转换方法。
首先必须建立每个基因的基线与试验数值之间的关系。优选的过程如下所述。选择一个基线组。基线组通常来自不患有目的疾病的群体。例如,如果想挑选出用于乳腺癌诊断的一组基因,那么,来源于未患乳腺癌患者的标本能够用作制备基线组。一旦选择出基线组,就可以计算出基线组样本中每一个基因的基因表达指标的算术平均值和标准差。这个指标通常是微阵列荧光强度的读数。计算所得的统计学数据接着用来计算每一个基因的基线值(X*标准差+均值)。这就是基因的基线读数,所有的其它样本将要与这个基线读数相比较。X是一个制定组合物的人挑选出来的严格的变量。X的数值越大就越严格。X数值的优选范围是0.5-3,更优选的是2-3,最优选的是3。
接着计算每一个试验样本(那些表现目的疾病的样本)与基线读数的比值。这些比值随后要转换成易于软件处理的基数为10的对数值。这种转化方法能够使表达下调的基因呈现出负值,这些负值对于在使用Wagner软件时根据Markman均方差算法进行优化是必须的。
含有转换的比值的预处理数据作为输入数据,替代那些通常用于金融分析目的的Wagner软件中资产回报值。
一旦制定出高效率边界,那么对于一个给定的输入水平(回报)或对应于边界上的一个点的方差,就可以挑选出一个优选的组合物。这些输入数值或方差是制定组合物的人预先确定的标准数据集。换言之,寻求最适组合物的人确定一个可以接受的输入水平(表明灵敏度)或者一个给定的方差水平(表明特异性),接着依据对应于输入水平或方差的高效率边界挑选基因。当选定了输入水平或方差时,Wagner软件就能够挑选出这样的基因。Wagner软件象在股票组合物中每一个股票都有一定的数量一样,它给组合物中的每一个基因都指定了一个重量。
通过将组合物中的基因在病人样本中表达的情况与用于建立组合物的差异表达基因的计算值相比较,就可以确定该样本是否患有组合物所诊断的疾病。优选的是,首先通过计算组合物中每个基因强度值与在筛选组合物的过程中指定给每个基因重量的乘积之和,产生一个组合物值。接着就可以通过(Y*标准差+基线组组合物值的均值)算出临界值,这里Y是一个严格的变量,同上面描述过的X具有一样的意义。如果一个样本的组合物值高于基线组的临界值,那么此样本就被划为患有此种疾病的一类。如果需要的话,可以根据那些提高可信度水平的已知统计学方法,重复上述过程。当然也可以重复进行上述过程,直到获得预期的最高准确度。
挑选组合物的过程和未知量的特性总结如下:
1.选择基线组
2.计算基线组样本中每个基因的均值和标准差
3.对每个基因进行(X*标准差+均值)计算。这就是基因的基线读数,其它的所有样本都要与这个基线读数相比较。X是一个严格的变量,X的数值越大就越严格。
4.计算根据步骤3得到的每个实验样本与基线读数之间的比值
5.通过数值转换,将小于1的比值转换为负数(例如使用基数为10的对数)。(下调的基因现在有了正确的负值,该负值对于MV方法进行优化是必须的)
6.将这些比值作为输入值,替换通常在该软件的应用中所使用的资产回报值
7.该软件将会描绘出高效的临界线,并且会沿此高效临界线上任意一点返回一组优选的组合物。
8.在此高效临界线上选择一个想要得到的回报值或者一个方差
9.通过计算每个基因强度值与在组合物筛选演算时产生的重量的乘积之和,计算每个样本的组合物的值。
10.Y与基线组合物值标准差的乘积加上基线组组合物值的均值,计算出临界值。大于此临界值的数值将被归为实验组。
11.也可以重复进行上述过程,直到获得预期的最高准确度。
将基线和试验的计算值颠倒过来,就可以产生第二个组合物。这样产生了一个由那些在原始的基线组中被上调的基因所组成的新的组合物。第一个组合物的值减去第二个组合物的值能够得到一个多个组合物基础上的新的分类值。
从基因表达数据中预先筛选基因以使其在筛选组合物的过程中作为输入数据的另一个有用方法是根据公式
计算所得的阈值,其中μt是患病样本子集的均值,μn是正常样本子集的均值,σt+σn代表联合标准差。根据如
的关系,一个除去了噪音的信号也能被用作预先选择的信号。这确保基于差异性调节而被预先筛选的基因能够以显著的临床方法被区分。这就是说,超过了检测设备噪音水平的信号适合完成测量参数的任务。为每一个根据这些标准预先筛选的标记物建立一个矩阵,矩阵中的列代表样本,行代表标记物,每一个元素都是根据
的关系进行标准化后所得到的标记物表达强度的测量值。其中I代表强度测量值。
使用这种为金融组合物软件建立输入数据的过程,也允许建立确定优选组合物的其它临界情况。例如,组合物的规模可以限定在一个固定的范围或一定数量的标记物。这可以通过使建立预先筛选的标准更严格(例如,用 代替
或者通过使用诸如限定组合物规模的程序化计算方法来完成。例如,可以将临界情况设置为从仅仅只有10个优选基因中筛选基因组合物的有效临界线的临界情况。也可以用所有预先筛选的基因来确定高效临界线,然后再限定要筛选的基因数量(例如,仅仅有10个基因)。
挑选组合物的过程也包括使用有渐进式规则。优选的是,这些规则是基于生物学和用于获得对得到临床结果的技术的理解基础上制定的。更优选的是,它们应用于优化方法的输出。例如,组合物筛选的均方差方法能够应用于乳腺癌样本中大量基因差异性表达的微阵列数据。这种方法得到的输出数据将会是一个优选的基因集合,这些基因包括那些既在外周血中表达也在患病乳腺组织中表达的基因。如果检测方法使用的样本来源于外周血而且某些基因既在乳腺癌中差异性表达,也能在外周血中差异性表达,那么能够应用一个渐进式规则,在这个规则中,从高效临界线中筛选的组合物排除了那些在外周血中差异性表达的基因。当然,这个规则可以在形成高效临界线之前应用,例如,在数据的预先筛选中应用该规则。
也能应用其它与正在谈论的生物学问题没有必然联系的渐进式规则。例如,一个特殊的基因或几个基因仅能够代表组合物的一定百分数的规则。商业上可以得到的软件,如Wagner软件就容易适应这些种类的探索规则。例如当除了精确度和准确度因素外的其它因素(例如预期许可费用)对包含一个或者更多基因的期望有影响时,这种方法是很有用的。
除了均方差关系外,其它关系也能够在本发明的方法中使用,这些关系能够根据预先确定的诸如分析的精确度和准确度的属性来优化组合物。例如马丁的同时平衡方法(Elton,Edwin J.and Martin J.Gruber(1987),Modern Portfolio TheoryInvestment Analysis,Third Edition,John Wiley,New York,1987)以及遗传学演算法(Davis,L.,(1989),Adapting Operator Probabilities in Genetic Algorithms,MorganKaufmann:San Mateo,pp.61-69)。也有许多方法采用均方差关系处理发生偏差的数据,例如标记物检测技术显示出已知的偏差。其中包括,例如半偏差法,该法中那些相对于基准信号有偏差的值(负数),即仅低于基准值的信号值,首先被平方,然后求平均,最后再开方。
本发明的项目中包括对基因表达分布情况的描述,这些基因构成了对于疾病的治疗,诊断,预后和评估疾病其它情况有用的标记组合物。这些描述被记录在能够被机器自动读取的媒介中,如计算机可读的媒介(磁性的,光学的等等)。项目中也包括在这样的媒介中评价基因表达分布的操作指南。例如,项目中可能由一张如何比较上述基因组合物中基因表达分布的计算机操作指南的CD ROM构成。项目中也可能有数字形式记录的基因表达分布,这样就可以与患者样本中的基因表达的数据相比较。或者,基因表达分布也可以用其它方式描述,例如用图解的记录方法。
根据本发明生产的不同种类的项目是显示基因表达分布的媒介或者是格式化的试样(assay)。可包括,例如,微阵列,在该微阵列上,互补序列或探针被固定成阵列,指示目的基因的序列与之结合,从而构成了一个表示它们存在的可读形式的行列式。当这样一个微阵列中包含一个优选的组合物时可以极大的节省时间,节约过程步骤,而且节约所获得的资源,这是通过使必须用于底物的cDNA或者寡聚核苷酸的数量最小,与样本的反应的次数最小化,分析人员读取的数据最少,加工过程最少和需要核实(有时)的数据最少来实现的。
根据本发明其它项目的可制成用于进行杂交的试剂盒,用于扩增的试剂盒,产生指示根据本发明的方法建立的组合物中基因表达水平信号的试剂盒。根据本发明制备的试剂盒包括用于检测基因表达分布的格式化的试样。这些项目中包含完成试样所需的全部或者部分材料,如试剂和操作指南。
实施例
实施例1:产生优化的组合物
最近从有代表性的11种不同类型癌症的组织标本中制备了基因表达数据。这些数据发表在Cancer Research 61:7388-7393,2001,和http://carrier.gnf.org/welsh/epican/.参见,Andrew I.Su et al.,题目是:“MolecularClassification of Human CarciSeq ID No.mas by Use of Gene ExpressionSignatures”。这个数据包含使用“U95”寡聚核苷酸微阵列(可以从Affymetrix公司商业购买)获得的强度测量值。
使用公开数据的基因表达测量值(荧光强度测量值)为一组标记物选择优化的基因表达组合物,用以检测一个循环细胞是否能指示乳腺癌,前列腺癌,卵巢癌,结肠直肠癌,或者肺癌的存在。这种循环细胞优选是上皮细胞。
本研究的数据来自下列样本:24例腺癌,12例浸润导管型乳腺腺癌,21例结肠直肠腺癌,23例卵巢腺癌,25例肺癌,数据还来自另外的样本:19例前列腺腺癌,12例乳腺癌,13例结肠癌,13例卵巢癌,13例卵巢癌和89例肺癌。
将来自正常组织标本的强度读数作为基线组,对每一个基因计算算术平均值,标准差以及计算(X*标准差+均值)值。在本例中严格变量X的数值指定为3。接着计算本试验中提到的每一个试验样本与基线值的比值。将比值转换成常用对数。这些数据接着作为Wagner软件的输入值。
这个过程是选择一个高效率临界线,此临界线使每一类型肿瘤的标记物数量最少,并且对于一个选定的差异水平具有最小的方差(在信噪比最佳的点选择)。通过软件的优化,选出了一个具有24个基因的组合物,组合物包含2个用于检测前列腺癌,5个用于检测乳腺癌,6个用于检测结肠癌,2个用于检测卵巢癌,9个用于检测肺癌(表1)。
表1
肿瘤类型 | 登记号 | 名称 | 描述 | 序列号(Seq IDNo.) |
PR | NM_001648 | KLK3 | 激肽释放酶3,(前列腺特异性抗原) | Seq ID No.1 |
PR | NM_005551 | KLK2 | 激肽释放酶2,前列腺的 | Seq ID No.2 |
BR | NM_004064 | CDKN1B | 细胞周期蛋白依赖性激酶抑制剂1B(p27,Kip1) | Seq ID No.34 |
BR | NM_002411 | MGB1 | 乳腺珠蛋白1(mammaglobin 1) | Seq ID No.3 |
BR | NM_005264 | GFRA1 | α1GDNF家族受体 | Seq ID No.4 |
BR | 无 | C18ORF1 | 18号染色体开放读码框1 | Seq ID No.98 |
BR | NM_000095 | COMP | 软骨寡聚基质蛋白 | Seq ID No.6 |
CO | NM_001804 | CDX1 | 尾部类型同源盒转录因子1 | Seq ID No.8 |
CO | NM_001046 | SLC12A2 | 溶质载体家族12(钠/钾/氯转运蛋白),成员2 | Seq ID No.9 |
CO | NM_001285 | CLCA1 | 氯离子通道,活化的钙,家族成员1 | Seq ID No.11 |
CO | NM_007052 | SEQ ID NO.X1 | NADPH氧化酶1 | Seq ID No.13 |
CO | NM_002457 | MUC2 | 黏蛋白2,肠道的/气管的 | Seq ID No.14 |
CO | NM_004063 | CDH17 | 钙粘连素17,LI钙粘连素 | Seq ID No.15 |
LU-A | NM_021950 | MS4A2 | 4个跨膜区,A亚家族,成员2 | Seq ID No.17 |
LU-A | NM_000964 | ASAHL | N-酰基神经鞘氨醇氨基水解酶(酸性神经酰胺酶)类似物 | Seq ID No.18 |
LU-A | NM_006495 | EVI2B | 亲环境病毒结合位点2B | Seq ID No.20 |
LU-A | NM_006864 | LILRB3 | 白细胞免疫球蛋白样受体,B亚家族 | Seq ID No.21 |
LU-A | X67301 | 无 | 编码H.sapiens的IgM免疫球蛋白重链恒定区的mRNA(Ab63) | Seq ID No.22 |
LU-A | NM_00123 | HLA-DQB1 | II类主要组织相容性复合物,1βDQ抗原 | Seq ID No.23 |
LU-S | NM_000673 | ADH7 | 乙醇脱氢酶7(IV型),μ或δ多肽 | Seq ID No.24 |
LU-S | NM_003722 | TP63 | 63KD的肿瘤蛋白,与p53蛋白有高同源性 | Seq ID No.26 |
LU-S | 无 | SOX2 | SRY(性别决定区Y)盒2 | Seq ID No.32 |
OV | NM_000906 | NPR1 | 利钠肽受体A/鸟苷酸环化酶A | Seq IDNo.28,29 |
OV | NM_000378 | WT1 | Wilms肿瘤1 | Seq ID No.30 |
实施例2:渐进式步骤
一个渐进式规则可以进一步应用于从实施例1中所得到的组合物。那即是说,该规则说明,如果被测定的基因/标记物可能在外周血中表达,或者是特征明显的组织标记物(例如,PSA,乳腺珠蛋白(mammaglobin 1)等),那么将这样的基因/标记物从组合物中去除。通过应用这种方法,能够建立一个用于筛选的优化的基因/标记物组合物,病人的样本是通过分析在外周血中发现的成分,如上皮细胞而获得的。表2显示了经过挑选得到的含有31个基因的组合物。
表2
肿瘤类型 | 登记号 | 名称 | 描述 | 序列号(Seq ID No.) |
PR | Hs.2784 | KIAA0293 | KIAA0293蛋白 | Seq ID No.67 |
PR | NM_006562 | LBX1 | 与D.melaSeq ID No.gaster成熟瓢虫同源域结构蛋白相似的转录因了 | Seq ID No.33 |
PR | NM_016026 | LOC51109 | CGI-82蛋白 | Seq ID No.34 |
PR | HG2261_HT2352 | 无 | 抗原 | Seq ID No.99 |
PR | NM_012449 | STEAP | 六次跨膜的前列腺上皮抗原 | Seq ID No.35 |
PR | NM_001634 | AMD1 | S-腺苷甲硫氨酸脱羧酶1 | Seq ID No.36 |
PR | HG2261_HT2351 | 无 | 抗原 | Seq ID No.100 |
PR | NM_006457 | LIM | LIM蛋白(与大鼠蛋白激酶C结合物相似) | Seq ID No.37 |
BR | NM_005853 | IPX5 | 易洛魁(inoquois)同源异形盒蛋白5 | Seq ID No.38 |
BR | NM_005264 | GFRA1 | α1GDNF家族受体 | Seq ID No.39,40 |
BR | 无 | C18ORF1 | 18号染色体开放读码框1 | Seq ID No.98 |
BR | NM_000095 | COMP | 软骨寡聚基质蛋白(假软骨发育不全,骨骺发育不良1型,多发性的) | Seq ID No.41,42 |
CO | NM_001265 | CDX2 | 尾部类型同源盒转录因子2 | Seq ID No.43 |
CO | NM_001046 | SLC12A2 | 溶质载体家族12(钠/钾/氯转运蛋白),成员2 | Seq ID No.44,45 |
CO | NM_001285 | CLCA1 | 氯离子通道,活化的钙,家族成员1 | Seq ID No.46,47 |
CO | NM_004063 | CDH17 | 钙粘连素17,LI钙粘连素(肝-肠) | Seq ID No.48,49 |
OV | NM_000906 | NPR1 | 利钠肽受体A/鸟苷酸环化酶A(心房利钠肽受体A) | Seq ID No.50,51 |
OV | NM_005504 | BCAT1 | 支链氨基转移酶1,胞液的 | Seq ID No.52 |
OV | NM_002398 | MES1 | Meis1(小鼠)同系物 | Scq ID No.53 |
OV | 无 | SPON1 | Spondin 1,(f-Spondlin)细胞外基质蛋白 | Seq ID No.69 |
OV | NM_001692 | 无 | M25809:人细胞膜内质子泵亚单位mRNA,GenBank:M25809 | Seq ID No.54 |
OV | NM_002774 | KLK6 | 激肽释放酶6(甘油磷酸钙,酶) | Seq ID No.55 |
LU-A | Nm_000964 | ASAHL | N-酰基神经鞘氨醇氨基水解酶(酸性神经酰胺酶)类似物 | Seq ID No.56,57 |
LU-A | NM_002838 | PTPRC | 蛋白酪氨酸磷酸化酶,受体类型,C | Seq ID No.58 |
LU-A | NM_015364 | MD-2 | MD-2蛋白 | Seq ID No.59 |
LU-A | NM_006875 | PIM2 | pim-2癌基因 | Seq ID No.60 |
LU-S | NM_005554 | KRT6A | 角蛋白6A | Seq ID No.61 |
LU-S | NM_000673 | ADH7 | 乙醇脱氢酶7(IV型),μ或δ多肽 | Seq ID No.62,63 |
LU-S | NM_003722 | TP63 | 63KD的肿瘤蛋白,与p53蛋白有高同源性 | Seq ID No.64,65 |
LU-S | 无 | SOX2 | SRY(性别决定区Y)盒2 | Seq ID No.32 |
LU-S | NM_005688 | ABCC5 | ATP结合盒,C亚家族(CFTR/MPR),成员5 | Seq ID No.66 |
实施例3:预后组合物
用一个已知临床结果的病人样本集检验根据本发明的方法筛选的组合物。
在van’t Veer,L.J et al.Genen Expression Profiling Predicts Clinical Outcome of BreastCaner,Nature,415,530-536,(2002)中公开了这个样本集,在此并入本微作为参考。在van’t Veer,L.J的研究中,乳腺组织样本来自78位患有单发乳腺肿瘤的病人。所有这些病人的年龄都小于55岁,并且肿瘤小于5厘米。所有病人的淋巴结都没有肿大。有34位病人在5年内有肿瘤的远处转移,44位患者同一时期没有发生远处转移。
在参考文献里描述了样本的制备和基因表达分布情况。在对不同预后(肿瘤发生了转移与没有发生转移)的患者的样本中5000个具有差异表达的基因进行了分析之后,挑选了70个基因作为用于诊断预后的标记组合物。这种选择是先自行分类,然后进行相关系数的分析。这是通过计算每一个基因的表达与疾病结果的相关系数来完成的。将那些通过这种分析得到的与疾病有显著相关的基因排列在5个连续的组中,根据“leave-one-out”的方法进行比较,直到筛选出具有70个基因的“优化”组合物。
将来自上述研究的数据根据本发明的方法进一步处理。54号样本被发现有高漏诊率,因而在进一步的分析中被排除。将没有发生肿瘤转移的样本作为基线,计算每一个基因强度测量值的均值和标准差。接着计算每一个基线基因的差异值X*(标准差+均值)(X的值指定为3)。使用这个值能够确保得到的组合物是严格的。计算每一个有转移的样本的差异值与基线值的比值。将这个比值转换为常用对数。然后将此数据输入到Wagner软件中得到一个高效临界线,从这个临界线得到一个由16个基因构成的组合物。将基线值和试验值颠倒过来计算比值,得到第二个由12种在非转移病例中代表上调基因的组合物。第一种组合物的值减去第二种组合物的值,得到由所有28个基因组成的联合组合物的值。这个最终的组合物由来自序列Seq ID No.70-97中的基因组成。这个组合物中有17种基因也在参考文献中描述过。经过确定的组合物的基因如下。(Seq IDNo.70,Seq ID No.72,Seq ID No.73-77,Seq ID No.79,Seq ID No.80,Seq ID No.85,Seq ID No.87,Seq ID No.91-93,Seq ID No.95和Seq ID No.97)
28个基因列表(2个组合物)
在转移病人中上调的基因(组合物1)
Cntig53226_RC | Seq.ID No.89 |
NM_012214 | Seq.ID No.82 |
NM_020386 | Seq.ID No.86 |
NM_004504 | Seq.ID No.81 |
AA555029_RC | Seq.ID No.70 |
AL080059 | Seq.ID No.74 |
AF055033 | Seq.ID No.73 |
NM_016448 | Seq.ID No.85 |
Contig40831_RC | Seq.ID No.95 |
Contig63649_RC | Seq.ID No.91 |
Contig24252_RC | Seq.ID No.93 |
NM_000436 | Seq.ID No.75 |
NM_002019 | Seq.ID No.77 |
Contig55313_RC | Seq.ID No.90 |
Contig25991 | Seq.ID No.97 |
NM_000788 | Seq.ID No.76 |
在没有发生肿瘤转移的患者中上调的基因(组合物2)AB033007 | Seq.ID No.71 |
Contig42421_RC | Seq.ID No.96 |
NM_003748 | Seq.ID No.78 |
NM_013262 | Seq.ID No.83 |
NM_003862 | Seq.ID No.79 |
NM_003882 | Seq.ID No.80 |
Contig48328_RC | Seq.ID No.87 |
NM_015416 | Seq.ID No.84 |
AB037863 | Seq.ID No.72 |
Contig27312_RC | Seq.ID No.88 |
Contig32125_RC | Seq.ID No.92 |
Contig49670_RC | Seq.ID No.94 |
17个与文献中重复的基因
分类名称 | |
NM_003862 | Seq.ID No.79 |
NM_003882 | Seq.ID No.80 |
Contig48328_RC | Seq.ID No.87 |
AA555029_RC | Seq.ID No.70 |
AL080059 | Seq.ID No.74 |
AF055033 | Seq.ID No.73 |
AF055033 | Seq.ID No.73 |
NM_016448 | Seq.ID No.85 |
AB037863 | Seq.ID No.72 |
Contig40831_RC | Seq.ID No.95 |
Contig63649_RC | Seq.ID No.91 |
Contig24252_RC | Seq.ID No.93 |
NM_000436 | Seq.ID No.75 |
NM_002019 | Seq.ID No.77 |
Contig32125_RC | Seq.ID No.92 |
Contig25991 | Seq.ID No.97 |
NM_000788 | Seq.ID No.76 |
这两个组合物接着通过比较根据本发明的方法得到的微阵列中基因表达数据,用以确定78例原始样本的预后,检验参考文献中记载的分类的精确度。在包含有70个基因的组合物的实例中,根据一个经过优化的倾向于包括将模糊的信号作为不良预后(85%使用绝对阈值)的阈值,81%的样本能够被正确的判断。这个组合物由于使用了优化的阈值(5例使用绝对阈值),使3个有不良预后的病人被错误地归为有良好预后。12个有良好预后的病人被错误地归为有良好预后,然而当使用优化的阈值时(8例使用绝对阈值),他们有不良的预后。
在包含有28个基因的组合物的实例中,根据一个经过优化的倾向于包括将模糊的信号作为不良预后的(绝对阈值的93%)阈值,94%的样本能够被正确的判断。这个组合物由于使用了优化的阈值(5例使用绝对阈值),使3例预后不良的病人被错误地归为预后良好。3个有良好预后的病人被错误地归为有良好的预后,然而当使用优化的阈值时(2个使用绝对阈值),他们有不良的预后。
很明显,通过比较上述两个组合物可以发现,根据本发明的方法所选择的组合物比那些与其比较的组合物更经济,得到的结果更精确和更可靠。
序列表
<110>FOLLOW,TO
WANG,YIXIN
<120>癌症诊断组合物
<130>CDS 269 US NP
<150>60/368,667
<151>2002-03-29
<160>100
<170>PatentIn version 3.1
<210>1
<211>1466
<212>DNA
<213>人
<400>1
agccccaagc ttaccacctg cacccggaga gctgtgtgtc accatgtggg tcccggttgt 60
cttcctcacc ctgtccgtga cgtggattgg tgctgcaccc ctcatcctgt ctcggattgt 120
gggaggctgg gagtgcgaga agcattccca accctggcag gtgcttgtgg cctctcgtgg 180
cagggcagtc tgcggcggtg ttctggtgca cccccagtgg gtcctcacag ctgcccactg 240
catcaggaac aaaagcgtga tcttgctggg tcggcacagc ctgtttcatc ctgaagacac 300
aggccaggta tttcaggtca gccacagctt cccacacccg ctctacgata tgagcctcct 360
gaagaatcga ttcctcaggc caggtgatga ctccagccac gacctcatgc tgctccgcct 420
gtcagagcct gccgagctca cggatgctgt gaaggtcatg gacctgccca cccaggagcc 480
agcactgggg accacctgct acgcctcagg ctggggcagc attgaaccag aggagttctt 540
gaccccaaag aaacttcagt gtgtggacct ccatgttatt tccaatgacg tgtgtgcgca 600
agttcaccct cagaaggtga ccaagttcat gctgtgtgct ggacgctgga cagggggcaa 660
aagcacctgc tcgggtgatt ctgggggccc acttgtctgt aatggtgtgc ttcaaggtat 720
cacgtcatgg ggcagtgaac catgtgccct gcccgaaagg ccttccctgt acaccaaggt 780
ggtgcattac cggaagtgga tcaaggacac catcgtggcc aacccctgag cacccctatc 840
aaccccctat tgtagtaaac ttggaacctt ggaaatgacc aggccaagac tcaagcctcc 900
ccagttctac tgacctttgt ccttaggtgt gaggtccagg gttgctagga aaagaaatca 960
gcagacacag gtgtagacca gagtgtttct taaatggtgt aattttgtcc tctctgtgtc 1020
ctggggaata ctggccatgc ctggagacat atcactcaat ttctctgagg acacagatag 1080
gatggggtgt ctgtgttatt tgtggggtac agagatgaaa gaggggtggg atccacactg 1140
agagagtgga gagtgacatg tgctggacac tgtccatgaa gcactgagca gaagctggag 1200
gcacaacgca ccagacactc acagcaagga tggagctgaa aacataaccc actctgtcct 1260
ggaggcactg ggaagcctag agaaggctgt gagccaagga gggagggtct tcctttggca 1320
tgggatgggg atgaagtaag gagagggact ggaccccctg gaagctgatt cactatgggg 1380
ggaggtgtat tgaagtcctc cagacaaccc tcagatttga tgatttccta gtagaactca 1440
cagaaataaa gagctgttat actgtg 1466
<210>2
<211>786
<212>DNA
<213>人
<400>2
atgtgggacc tggttctctc catcgccttg tctgtggggt gcactggtgc cgtgcccctc 60
atccagtctc ggattgtggg aggctgggag tgtgagaagc attcccaacc ctggcaggtg 120
gctgtgtaca gtcatggatg ggcacactgt gggggtgtcc tggtgcaccc ccagtgggtg 180
ctcacagctg cccattgcct aaagaagaat agccaggtct ggctgggtcg gcacaacctg 240
tttgagcctg aagacacagg ccagagggtc cctgtcagcc acagcttccc acacccgctc 300
tacaatatga gccttctgaa gcatcaaagc cttagaccag atgaagactc cagccatgac 360
ctcatgctgc tccgcctgtc agagcctgcc aagatcacag atgttgtgaa ggtcctgggc 420
ctgcccaccc aggagccagc actggggacc acctgctacg cctcaggctg gggcagcatc 480
gaaccagagg agttcttgcg ccccaggagt cttcagtgtg tgagcctcca tctcctgtcc 540
aatgacatgt gtgctagagc ttactctgag aaggtgacag agttcatgtt gtgtgctggg 600
ctctggacag gtggtaaaga cacttgtggg ggtgattctg ggggtccact tgtctgtaat 660
ggggtgcttc aaggtatcac atcatggggc cctgagccat gtgccctgcc tgaaaagcct 720
gctgtgtaca ccaaggtggt gcattaccgg aagtggatca aggacaccat cgcagccaac 780
ccctga 786
<210>3
<211>503
<212>DNA
<213>人
<400>3
gacagcggct tccttgatcc ttgccacccg cgactgaaca ccgacagcag cagcctcacc 60
atgaagttgc tgatggtcct catgctggcg gccctctccc agcactgcta cgcaggctct 120
ggctgcccct tattggagaa tgtgatttcc aagacaatca atccacaagt gtctaagact 180
gaatacaaag aacttcttca agagttcata gacgacaatg ccactacaaa tgccatagat 240
gaattgaagg aatgttttct taaccaaacg gatgaaactc tgagcaatgt tgaggtgttt 300
atgcaattaa tatatgacag cagtctttgt gatttatttt aactttctgc aagacctttg 360
gctcacagaa ctgcagggta tggtgagaaa ccaactacgg attgctgcaa accacacctt 420
ctctttctta tgtcttttta ctacaaacta caagacaatt gttgaaacct gctatacatg 480
tttattttaa taaattgatg gca 503
<210>4
<211>2560
<212>DNA
<213>人
<400>4
gaattccggc cagaagaaat ctggcctcgg aacacgccat tctccgcgcc gcttccaata 60
accactaaca tccctaacga gcatccgagc cgagggctct gctcggaaat cgtcctggcc 120
caactcggcc cttcgagctc tcgaagatta ccgcatctat tttttttttc ttttttttct 180
tttcctagcg cagataaagt gagcccggaa agggaaggag ggggcgggga caccattgcc 240
ctgaaagaat aaataagtaa ataaacaaac tggctcctcg ccgcagctgg acgcggtcgg 300
ttgagtccag gttgggtcgg acctgaaccc ctaaaagcgg aaccgcctcc cgccctcgcc 360
atcccggagc tgagtcgccg gcggcggtgg ctgctgccag acccggagtt tcctctttca 420
ctggatggag ctgaactttg ggcggccaga gcagcacagc tgtccgggga tcgctgcacg 480
ctgagctccc tcggcaagac ccagcggcgg ctcgggattt ttttgggggg gcggggacca 540
gccccgcgcc ggcaccatgt tcctggcgac cctgtacttc gcgctgccgc tcttggactt 600
gctcctgtcg gccgaagtga gcggcggaga ccgcctggat tgcgtgaaag ccagtgatca 660
gtgcctgaag gagcagagct gcagcaccaa gtaccgcacg ctaaggcagt gcgtggcggg 720
caaggagacc aacttcagcc tggcatccgg cctggaggcc aaggatgagt gccgcagcgc 780
catggaggcc ctgaagcaga agtcgctcta caactgccgc tgcaagcggg gtatgaagaa 840
ggagaagaac tgcctgcgca tttactggag catgtaccag agcctgcagg gaaatgatct 900
gctggaggat tccccatatg aaccagttaa cagcagattg tcagatatat tccgggtggt 960
cccattcata tcagatgttt ttcagcaagt ggagcacatt cccaaaggga acaactgcct 1020
ggatgcagcg aaggcctgca acctcgacga catttgcaag aagtacaggt cggcgtacat 1080
caccccgtgc accaccagcg tgtccaacga tgtctgcaac cgccgcaagt gccacaaggc 1140
cctccggcag ttctttgaca aggtcccggc caagcacagc tacggaatgc tcttctgctc 1200
ctgccgggac atcgcctgca cagagcggag gcgacagacc atcgtgcctg tgtgctccta 1260
tgaagagagg gagaagccca actgtttgaa tttgcaggac tcctgcaaga cgaattacat 1320
ctgcagatct cgccttgcgg atttttttac caactgccag ccagagtcaa ggtctgtcag 1380
cagctgtcta aaggaaaact acgctgactg cctcctcgcc tactcggggc ttattggcac 1440
agtcatgacc cccaactaca tagactccag tagcctcagt gtggccccat ggtgtgactg 1500
cagcaacagt gggaacgacc tagaagagtg cttgaaattt ttgaatttct tcaaggacaa 1560
tacatgtctt aaaaatgcaa ttcaagcctt tggcaatggc tccgatgtga ccgtgtggca 1620
gccagccttc ccagtacaga ccaccactgc cactaccacc actgccctcc gggttaagaa 1680
caagcccctg gggccagcag ggtctgagaa tgaaattccc actcatgttt tgccaccgtg 1740
tgcaaattta caggcacaga agctgaaatc caatgtgtcg ggcaatacac acctctgtat 1800
ttccaatggt aattatgaaa aagaaggtct cggtgcttcc agccacataa ccacaaaatc 1860
aatggctgct cctccaagct gtggtctgag cccactgctg gtcctggtgg taaccgctct 1920
gtccacccta ttatctttaa cagaaacatc atagctgcat taaaaaaata caatatggac 1980
atgtaaaaag acaaaaacca agttatctgt ttcctgttct cttgtatagc tgaaattcca 2040
gtttaggagc tcagttgaga aacagttcca ttcaactgga acattttttt ttttcctttt 2100
aagaaagctt cttgtgatcc ttcggggctt ctgtgaaaaa cctgatgcag tgctccatcc 2160
aaactcagaa ggctttggga tatgctgtat tttaaaggga cagtttgtaa cttgggctgt 2220
aaagcaaact ggggctgtgt tttcgatgat gatgatcatc atgatcatga tgattttaac 2280
agttttactt ctggcctttc ctagctagag aaggagttaa tatttctaag gtaactccca 2340
tatctccttt aatgacattg atttctaatg atataaattt cagcctacat tgatgccaag 2400
cttttttgcc acaaagaaga ttcttaccaa gagtgggctt tgtggaaaca gctggtactg 2460
atgttcacct ttatatatgt actagcattt tccacgctga tgtttatgta ctgtaaacag 2520
ttctgcactc ttgtacaaaa gaaaaaacca cccggaattc 2560
<210>5
<211>2560
<212>DNA
<213>人
<400>5
gaattccggc cagaagaaat ctggcctcgg aacacgccat tctccgcgcc gcttccaata 60
accactaaca tccctaacga gcatccgagc cgagggctct gctcggaaat cgtcctggcc 120
caactcggcc cttcgagctc tcgaagatta ccgcatctat tttttttttc ttttttttct 180
tttcctagcg cagataaagt gagcccggaa agggaaggag ggggcgggga caccattgcc 240
ctgaaagaat aaataagtaa ataaacaaac tggctcctcg ccgcagctgg acgcggtcgg 300
ttgagtccag gttgggtcgg acctgaaccc ctaaaagcgg aaccgcctcc cgccctcgcc 360
atcccggagc tgagtcgccg gcggcggtgg ctgctgccag acccggagtt tcctctttca 420
ctggatggag ctgaactttg ggcggccaga gcagcacagc tgtccgggga tcgctgcacg 480
ctgagctccc tcggcaagac ccagcggcgg ctcgggattt ttttgggggg gcggggacca 540
gccccgcgcc ggcaccatgt tcctggcgac cctgtacttc gcgctgccgc tcttggactt 600
gctcctgtcg gccgaagtga gcggcggaga ccgcctggat tgcgtgaaag ccagtgatca 660
gtgcctgaag gagcagagct gcagcaccaa gtaccgcacg ctaaggcagt gcgtggcggg 720
caaggagacc aacttcagcc tggcatccgg cctggaggcc aaggatgagt gccgcagcgc 780
catggaggcc ctgaagcaga agtcgctcta caactgccgc tgcaagcggg gtatgaagaa 840
ggagaagaac tgcctgcgca tttactggag catgtaccag agcctgcagg gaaatgatct 900
gctggaggat tccccatatg aaccagttaa cagcagattg tcagatatat tccgggtggt 960
cccattcata tcagatgttt ttcagcaagt ggagcacatt cccaaaggga acaactgcct 1020
ggatgcagcg aaggcctgca acctcgacga catttgcaag aagtacaggt cggcgtacat 1080
caccccgtgc accaccagcg tgtccaacga tgtctgcaac cgccgcaagt gccacaaggc 1140
cctccggcag ttctttgaca aggtcccggc caagcacagc tacggaatgc tcttctgctc 1200
ctgccgggac atcgcctgca cagagcggag gcgacagacc atcgtgcctg tgtgctccta 1260
tgaagagagg gagaagccca actgtttgaa tttgcaggac tcctgcaaga cgaattacat 1320
ctgcagatct cgccttgcgg atttttttac caactgccag ccagagtcaa ggtctgtcag 1380
cagctgtcta aaggaaaact acgctgactg cctcctcgcc tactcggggc ttattggcac 1440
agtcatgacc cccaactaca tagactccag tagcctcagt gtggccccat ggtgtgactg 1500
cagcaacagt gggaacgacc tagaagagtg cttgaaattt ttgaatttct tcaaggacaa 1560
tacatgtctt aaaaatgcaa ttcaagcctt tggcaatggc tccgatgtga ccgtgtggca 1620
gccagccttc ccagtacaga ccaccactgc cactaccacc actgccctcc gggttaagaa 1680
caagcccctg gggccagcag ggtctgagaa tgaaattccc actcatgttt tgccaccgtg 1740
tgcaaattta caggcacaga agctgaaatc caatgtgtcg ggcaatacac acctctgtat 1800
ttccaatggt aattatgaaa aagaaggtct cggtgcttcc agccacataa ccacaaaatc 1860
aatggctgct cctccaagct gtggtctgag cccactgctg gtcctggtgg taaccgctct 1920
gtccacccta ttatctttaa cagaaacatc atagctgcat taaaaaaata caatatggac 1980
atgtaaaaag acaaaaacca agttatctgt ttcctgttct cttgtatagc tgaaattcca 2040
gtttaggagc tcagttgaga aacagttcca ttcaactgga acattttttt ttttcctttt 2100
aagaaagctt cttgtgatcc ttcggggctt ctgtgaaaaa cctgatgcag tgctccatcc 2160
aaactcagaa ggctttggga tatgctgtat tttaaaggga cagtttgtaa cttgggctgt 2220
aaagcaaact ggggctgtgt tttcgatgat gatgatcatc atgatcatga tgattttaac 2280
agttttactt ctggcctttc ctagctagag aaggagttaa tatttctaag gtaactccca 2340
tatctccttt aatgacattg atttctaatg atataaattt cagcctacat tgatgccaag 2400
cttttttgcc acaaagaaga ttcttaccaa gagtgggctt tgtggaaaca gctggtactg 2460
atgttcacct ttatatatgt actagcattt tccacgctga tgtttatgta ctgtaaacag 2520
ttctgcactc ttgtacaaaa gaaaaaacca cccggaattc 2560
<210>6
<211>2439
<212>DNA
<213>人
<400>6
cagcacccag ctccccgcca ccgccatggt ccccgacacc gcctgcgttc ttctgctcac 60
cctggctgcc ctcggcgcgt ccggacaggg ccagagcccg ttgggctcag acctgggccc 120
gcagatgctt cgggaactgc aggaaaccaa cgcggcgctg caggacgtgc gggactggct 180
gcggcagcag gtcagggaga tcacgttcct gaaaaacacg gtgatggagt gtgacgcgtg 240
cgggatgcag cagtcagtac gcaccggcct acccagcgtg cggcccctgc tccactgcgc 300
gcccggcttc tgcttccccg gcgtggcctg catccagacg gagagcggcg gccgctgcgg 360
cccctgcccc gcgggcttca cgggcaacgg ctcgcactgc accgacgtca acgagtgcaa 420
cgcccacccc tgcttccccc gagtccgctg tatcaacacc agcccggggt tccgctgcga 480
ggcttgcccg ccggggtaca gcggccccac ccaccagggc gtggggctgg ctttcgccaa 540
ggccaacaag caggtttgca cggacatcaa cgagtgtgag accgggcaac ataactgcgt 600
ccccaactcc gtgtgcatca acacccgggg ctccttccag tgcggcccgt gccagcccgg 660
cttcgtgggc gaccaggcgt ccggctgcca gcgcggcgca cagcgcttct gccccgacgg 720
ctcgcccagc gagtgccacg agcatgcaga ctgcgtccta gagcgcgatg gctcgcggtc 780
gtgcgtgtgt cgcgttggct gggccggcaa cgggatcctc tgtggtcgcg acactgacct 840
agacggcttc ccggacgaga agctgcgctg cccggagccg cagtgccgta aggacaactg 900
cgtgactgtg cccaactcag ggcaggagga tgtggaccgc gatggcatcg gagacgcctg 960
cgatccggat gccgacgggg acggggtccc caatgaaaag gacaactgcc cgctggtgcg 1020
gaacccagac cagcgcaaca cggacgagga caagtggggc gatgcgtgcg acaactgccg 1080
gtcccagaag aacgacgacc aaaaggacac agaccaggac ggccggggcg atgcgtgcga 1140
cgacgacatc gacggcgacc ggatccgcaa ccaggccgac aactgcccta gggtacccaa 1200
ctcagaccag aaggacagtg atggcgatgg tataggggat gcctgtgaca actgtcccca 1260
gaagagcaac ccggatcagg cggatgtgga ccacgacttt gtgggagatg cttgtgacag 1320
cgatcaagac caggatggag acggacatca ggactctcgg gacaactgtc ccacggtgcc 1380
taacagtgcc caggaggact cagaccacga tggccagggt gatgcctgcg acgacgacga 1440
cgacaatgac ggagtccctg acagtcggga caactgccgc ctggtgccta accccggcca 1500
ggaggacgcg gacagggacg gcgtgggcga cgtgtgccag gacgactttg atgcagacaa 1560
ggtggtagac aagatcgacg tgtgtccgga gaacgctgaa gtcacgctca ccgacttcag 1620
ggccttccag acagtcgtgc tggacccgga gggtgacgcg cagattgacc ccaactgggt 1680
ggtgctcaac cagggaaggg agatcgtgca gacaatgaac agcgacccag gcctggctgt 1740
gggttacact gccttcaatg gcgtggactt cgagggcacg ttccatgtga acacggtcac 1800
ggatgacgac tatgcgggct tcatctttgg ctaccaggac agctccagct tctacgtggt 1860
catgtggaag cagatggagc aaacgtattg gcaggcgaac cccttccgtg ctgtggccga 1920
gcctggcatc caactcaagg ctgtgaagtc ttccacaggc cccggggaac agctgcggaa 1980
cgctctgtgg catacaggag acacagagtc ccaggtgcgg ctgctgtgga aggacccgcg 2040
aaacgtgggt tggaaggaca agaagtccta tcgttggttc ctgcagcacc ggccccaagt 2100
gggctacatc agggtgcgat tctatgaggg ccctgagctg gtggccgaca gcaacgtggt 2160
cttggacaca accatgcggg gtggccgcct gggggtcttc tgcttctccc aggagaacat 2220
catctgggcc aacctgcgtt accgctgcaa tgacaccatc ccagaggact atgagaccca 2280
tcagctgcgg caagcctagg gaccagggtg aggacccgcc ggatgacagc caccctcacc 2340
gcggctggat gggggctctg cacccagccc aaggggtggc cgtcctgagg gggaagtgag 2400
aagggctcag agaggacaaa ataaagtgtg tgtgcaggg 2439
<210>7
<211>2439
<212>DNA
<213>人
<400>7
cagcacccag ctccccgcca ccgccatggt ccccgacacc gcctgcgttc ttctgctcac 60
cctggctgcc ctcggcgcgt ccggacaggg ccagagcccg ttgggctcag acctgggccc 120
gcagatgctt cgggaactgc aggaaaccaa cgcggcgctg caggacgtgc gggactggct 180
gcggcagcag gtcagggaga tcacgttcct gaaaaacacg gtgatggagt gtgacgcgtg 240
cgggatgcag cagtcagtac gcaccggcct acccagcgtg cggcccctgc tccactgcgc 300
gcccggcttc tgcttccccg gcgtggcctg catccagacg gagagcggcg gccgctgcgg 360
cccctgcccc gcgggcttca cgggcaacgg ctcgcactgc accgacgtca acgagtgcaa 420
cgcccacccc tgcttccccc gagtccgctg tatcaacacc agcccggggt tccgctgcga 480
ggcttgcccg ccggggtaca gcggccccac ccaccagggc gtggggctgg ctttcgccaa 540
ggccaacaag caggtttgca cggacatcaa cgagtgtgag accgggcaac ataactgcgt 600
ccccaactcc gtgtgcatca acacccgggg ctccttccag tgcggcccgt gccagcccgg 660
cttcgtgggc gaccaggcgt ccggctgcca gcgcggcgca cagcgcttct gccccgacgg 720
ctcgcccagc gagtgccacg agcatgcaga ctgcgtccta gagcgcgatg gctcgcggtc 780
gtgcgtgtgt cgcgttggct gggccggcaa cgggatcctc tgtggtcgcg acactgacct 840
agacggcttc ccggacgaga agctgcgctg cccggagccg cagtgccgta aggacaactg 900
cgtgactgtg cccaactcag ggcaggagga tgtggaccgc gatggcatcg gagacgcctg 960
cgatccggat gccgacgggg acggggtccc caatgaaaag gacaactgcc cgctggtgcg 1020
gaacccagac cagcgcaaca cggacgagga caagtggggc gatgcgtgcg acaactgccg 1080
gtcccagaag aacgacgacc aaaaggacac agaccaggac ggccggggcg atgcgtgcga 1140
cgacgacatc gacggcgacc ggatccgcaa ccaggccgac aactgcccta gggtacccaa 1200
ctcagaccag aaggacagtg atggcgatgg tataggggat gcctgtgaca actgtcccca 1260
gaagagcaac ccggatcagg cggatgtgga ccacgacttt gtgggagatg cttgtgacag 1320
cgatcaagac caggatggag acggacatca ggactctcgg gacaactgtc ccacggtgcc 1380
taacagtgcc caggaggact cagaccacga tggccagggt gatgcctgcg acgacgacga 1440
cgacaatgac ggagtccctg acagtcggga caactgccgc ctggtgccta accccggcca 1500
ggaggacgcg gacagggacg gcgtgggcga cgtgtgccag gacgactttg atgcagacaa 1560
ggtggtagac aagatcgacg tgtgtccgga gaacgctgaa gtcacgctca ccgacttcag 1620
ggccttccag acagtcgtgc tggacccgga gggtgacgcg cagattgacc ccaactgggt 1680
ggtgctcaac cagggaaggg agatcgtgca gacaatgaac agcgacccag gcctggctgt 1740
gggttacact gccttcaatg gcgtggactt cgagggcacg ttccatgtga acacggtcac 1800
ggatgacgac tatgcgggct tcatctttgg ctaccaggac agctccagct tctacgtggt 1860
catgtggaag cagatggagc aaacgtattg gcaggcgaac cccttccgtg ctgtggccga 1920
gcctggcatc caactcaagg ctgtgaagtc ttccacaggc cccggggaac agctgcggaa 1980
cgctctgtgg catacaggag acacagagtc ccaggtgcgg ctgctgtgga aggacccgcg 2040
aaacgtgggt tggaaggaca agaagtccta tcgttggttc ctgcagcacc ggccccaagt 2100
gggctacatc agggtgcgat tctatgaggg ccctgagctg gtggccgaca gcaacgtggt 2160
cttggacaca accatgcggg gtggccgcct gggggtcttc tgcttctccc aggagaacat 2220
catctgggcc aacctgcgtt accgctgcaa tgacaccatc ccagaggact atgagaccca 2280
tcagctgcgg caagcctagg gaccagggtg aggacccgcc ggatgacagc caccctcacc 2340
gcggctggat gggggctctg cacccagccc aaggggtggc cgtcctgagg gggaagtgag 2400
aagggctcag agaggacaaa ataaagtgtg tgtgcaggg 2439
<210>8
<211>1700
<212>DNA
<213>人
<400>8
haggtgagcg gttgctcgtc gtcggggcgg ccggcagcgg cggctccagg gcccagcatg 60
cgcgggggac cccgcggcca ccatgtatgt gggctatgtg ctggacaagg attcgcccgt 120
gtaccccggc ccagccaggc cagccagcct cggcctgggc ccggcaaact acggcccccc 180
ggccccgccc ccggcgcccc cgcagtaccc cgacttctcc agctactctc acgtggagcc 240
ggcccccgcg cccccgacgg cctggggggc gcccttccct gcgcccaagg acgactgggc 300
cgccgcctac ggcccgggcc ccgcggcccc tgccgccagc ccagcttcgc tggcattcgg 360
gccccctcca gactttagcc cggtgccggc gccccctggg cccggcccgg gcctcctggc 420
gcagcccctc gggggcccgg gcacaccgtc ctcgcccgga gcgcagaggc cgacgcccta 480
cgagtggatg cggcgcagcg tggcggccgg aggcggcggt ggcagcggta agactcggac 540
caaggacaag taccgcgtgg tctacaccga ccaccaacgc ctggagctgg agaaggagtt 600
tcattacagc cgttacatca caatccggcg gaaatcagag ctggctgcca atctggggct 660
cactgaacgg caggtgaaga tctggttcca aaaccggcgg gcaaaggagc gcaaagtgaa 720
caagaagaaa cagcagcagc aacagccccc acagccgccg atggcccacg acatcacggc 780
caccccagcc gggccatccc tggggggcct gtgtcccagc aacaccagcc tcctggccac 840
ctcctctcca atgcctgtga aagaggagtt tctgccatag ccccatgccc agcctgtgcg 900
ccgggggacc tggggactcg ggtgctggga gtgtggctcc tgtgggccca ggaggtctgg 960
tccgagtctc agccctgacc ttctgggaca tggtggacag tcacctatcc accctctgca 1020
tccccttggc ccattgtgtg cagtaagcct gttggataaa gaccttccag ctcctgtgtt 1080
ctagacctct gggggataag ggagtccagg gtggatgatc tcaatctccc gtgggcatct 1140
caagccccaa atggttgggg gaggggccta gacaaggctc caggccccac ctcctcctcc 1200
atacgttcag aggtgcagct ggaggcctgt gtggggacca cactgatcct ggagaaaagg 1260
gatggagctg aaaaagatgg aatgcttgca gagcatgacc tgaggaggga ggaacgtggt 1320
caactcacac ctgcctcttc tgcagcctca cctctacctg cccccatcat aagggcactg 1380
agcccttccc aggctggata ctaagcacaa agcccatagc actgggctct gatggctgct 1440
ccactgggtt acagaatcac agccctcatg atcattctca gtgagggctc tggattgaga 1500
gggaggccct gggaggagag aagggggcag agtcttccct accaggtttc tacacccccg 1560
ccaggctgcc catcagggcc cagggagccc ccagaggact ttattcggac caagcagagc 1620
tcacagctgg acaggtgttg tatatagagt ggaatctctt ggatgcagct tcaagaataa 1680
atttttcttc tcttttcaaa 1700
<210>9
<211>4098
<212>DNA
<213>人
<400>9
ggtggcctct gtggccgtcc aggctagcgg cggcccgcag gcggcgggga gaaagactct 60
ctcacctggt cttgcggctg tggccaccgc cggccagggg tgtggagggc gtgctgccgg 120
agacgtccgc cgggctctgc agttccgccg ggggtcgggc agctatggag ccgcggccca 180
cggcgccctc ctccggcgcc ccgggactgg ccggggtcgg ggagacgccg tcagccgctg 240
cgctggccgc agccagggtg gaactgcccg gcacggctgt gccctcggtg ccggaggatg 300
ctgcgcccgc gagccgggac ggcggcgggg tccgcgatga gggccccgcg gcggccgggg 360
acgggctggg cagacccttg gggcccaccc cgagccagag ccgtttccag gtggacctgg 420
tttccgagaa cgccgggcgg gccgctgctg cggcggcggc ggcggcggcg gcagcggcgg 480
cggctggtgc tggggcgggg gccaagcaga cccccgcgga cggggaagcc agcggcgaga 540
gcgagccagc taaaggcagc gaggaagcca agggccgctt ccgcgtgaac ttcgtggacc 600
cagctgcctc ctcgtcggct gaagacagcc tgtcagatgc tgccggggtc ggagtcgacg 660
ggcccaacgt gagcttccag aacggcgggg acacggtgct gagcgagggc agcagcctgc 720
actccggcgg cggcggcggc agtgggcacc accagcacta ctattatgat acccacacca 780
acacctacta cctgcgcacc ttcggccaca acaccatgga cgctgtgccc aggatcgatc 840
actaccggca cacagccgcg cagctgggcg agaagctgct ccggcctagc ctggcggagc 900
tccacgacga gctggaaaag gaaccttttg aggatggctt tgcaaatggg gaagaaagta 960
ctccaaccag agatgctgtg gtcacgtata ctgcagaaag taaaggagtc gtgaagtttg 1020
gctggatcaa gggtgtatta gtacgttgta tgttaaacat ttggggtgtg atgcttttca 1080
ttagattgtc atggattgtg ggtcaagctg gaataggtct atcagtcctt gtaataatga 1140
tggccactgt tgtgacaact atcacaggat tgtctacttc agcaatagca actaatggat 1200
ttgtaagagg aggaggagca tattatttaa tatctagaag tctagggcca gaatttggtg 1260
gtgcaattgg tctaatcttc gcctttgcca acgctgttgc agttgctatg tatgtggttg 1320
gatttgcaga aaccgtggtg gagttgctta aggaacattc catacttatg atagatgaaa 1380
tcaatgatat ccgaattatt ggagccatta cagtcgtgat tcttttaggt atctcagtag 1440
ctggaatgga gtgggaagca aaagctcaga ttgttctttt ggtgatccta cttcttgcta 1500
ttggtgattt cgtcatagga acatttatcc cactggagag caagaagcca aaagggtttt 1560
ttggttataa atctgaaata tttaatgaga actttgggcc cgattttcga gaggaagaga 1620
ctttcttttc tgtatttgcc atcttttttc ctgctgcaac tggtattctg gctggagcaa 1680
atatctcagg tgatcttgca gatcctcagt cagccatacc caaaggaaca ctcctagcca 1740
ttttaattac tacattggtt tacgtaggaa ttgcagtatc tgtaggttct tgtgttgttc 1800
gagatgccac tggaaacgtt aatgacacta tcgtaacaga gctaacaaac tgtacttctg 1860
cagcctgcaa attaaacttt gatttttcat cttgtgaaag cagtccttgt tcctatggcc 1920
taatgaacaa cttccaggta atgagtatgg tgtcaggatt tacaccacta atttctgcag 1980
gtatattttc agccactctt tcttcagcat tagcatccct agtgagtgct cccaaaatat 2040
ttcaggctct atgtaaggac aacatctacc cagctttcca gatgtttgct aaaggttatg 2100
ggaaaaataa tgaacctctt cgtggctaca tcttaacatt cttaattgca cttggattca 2160
tcttaattgc tgaactgaat gttattgcac caattatctc aaacttcttc cttgcatcat 2220
atgcattgat caatttttca gtattccatg catcacttgc aaaatctcca ggatggcgtc 2280
ctgcattcaa atactacaac atgtggatat cacttcttgg agcaattctt tgttgcatag 2340
taatgttcgt cattaactgg tgggctgcat tgctaacata tgtgatagtc cttgggctgt 2400
atatttatgt tacctacaaa aaaccagatg tgaattgggg atcctctaca caagccctga 2460
cttacctgaa tgcactgcag cattcaattc gtctttctgg agtggaagac cacgtgaaaa 2520
actttaggcc acagtgtctt gttatgacag gtgctccaaa ctcacgtcca gctttacttc 2580
atcttgttca tgatttcaca aaaaatgttg gtttgatgat ctgtggccat gtacatatgg 2640
gtcctcgaag acaagccatg aaagagatgt ccatcgatca agccaaatat cagcgatggc 2700
ttattaagaa caaaatgaag gcattttatg ctccagtaca tgcagatgac ttgagagaag 2760
gtgcacagta tttgatgcag gctgctggtc ttggtcgtat gaagccaaac acacttgtcc 2820
ttggatttaa gaaagattgg ttgcaagcag atatgaggga tgtggatatg tatataaact 2880
tatttcatga tgcttttgac atacaatatg gagtagtggt tattcgccta aaagaaggtc 2940
tggatatatc tcatcttcaa ggacaagaag aattattgtc atcacaagag aaatctcctg 3000
gcaccaagga tgtggtagta agtgtggaat atagtaaaaa gtccgattta gatacttcca 3060
aaccactcag tgaaaaacca attacacaca aagttgagga agaggatggc aagactgcaa 3120
ctcaaccact gttgaaaaaa gaatccaaag gccctattgt gcctttaaat gtagctgacc 3180
aaaagcttct tgaagctagt acacagtttc agaaaaaaca aggaaagaat actattgatg 3240
tctggtggct ttttgatgat ggaggtttga ccttattgat accttacctt ctgacgacca 3300
agaaaaaatg gaaagactgt aagatcagag tattcattgg tggaaagata aacagaatag 3360
accatgaccg gagagcgatg gctactttgc ttagcaagtt ccggatagac ttttctgata 3420
tcatggttct aggagatatc aataccaaac caaagaaaga aaatattata gcttttgagg 3480
aaatcattga gccatacaga cttcatgaag atgataaaga gcaagatatt gcagataaaa 3540
tgaaagaaga tgaaccatgg cgaataacag ataatgagct tgaactttat aagaccaaga 3600
cataccggca gatcaggtta aatgagttat taaaggaaca ttcaagcaca gctaatatta 3660
ttgtcatgag tctcccagtt gcacgaaaag gtgctgtgtc tagtgctctc tacatggcat 3720
ggttagaagc tctatctaag gacctaccac caatcctcct agttcgtggg aatcatcaga 3780
gtgtccttac cttctattca taaatgttct atacagtgga cagccctcca gaatggtact 3840
tcagtgccta gtgtagtaac ctgaaatctt caatgacaca ttaacatcac aatggcgaat 3900
ggtgactttt ctttcacgat ttcattaatt tgaaagcaca caggaaagct tgctccattg 3960
ataacgtgta tggagacttc ggttttagtc aattccatat ctcaatctta atggtgattc 4020
ttctctgttg aactgaagtt tgtgagagta gttttccttt gctacttgaa tagcaataaa 4080
agcgtgttaa ctttttgg 4098
<210>10
<211>4098
<212>DNA
<213>人
<400>10
ggtggcctct gtggccgtcc aggctagcgg cggcccgcag gcggcgggga gaaagactct 60
ctcacctggt cttgcggctg tggccaccgc cggccagggg tgtggagggc gtgctgccgg 120
agacgtccgc cgggctctgc agttccgccg ggggtcgggc agctatggag ccgcggccca 180
cggcgccctc ctccggcgcc ccgggactgg ccggggtcgg ggagacgccg tcagccgctg 240
cgctggccgc agccagggtg gaactgcccg gcacggctgt gccctcggtg ccggaggatg 300
ctgcgcccgc gagccgggac ggcggcgggg tccgcgatga gggccccgcg gcggccgggg 360
acgggctggg cagacccttg gggcccaccc cgagccagag ccgtttccag gtggacctgg 420
tttccgagaa cgccgggcgg gccgctgctg cggcggcggc ggcggcggcg gcagcggcgg 480
cggctggtgc tggggcgggg gccaagcaga cccccgcgga cggggaagcc agcggcgaga 540
gcgagccagc taaaggcagc gaggaagcca agggccgctt ccgcgtgaac ttcgtggacc 600
cagctgcctc ctcgtcggct gaagacagcc tgtcagatgc tgccggggtc ggagtcgacg 660
ggcccaacgt gagcttccag aacggcgggg acacggtgct gagcgagggc agcagcctgc 720
actccggcgg cggcggcggc agtgggcacc accagcacta ctattatgat acccacacca 780
acacctacta cctgcgcacc ttcggccaca acaccatgga cgctgtgccc aggatcgatc 840
actaccggca cacagccgcg cagctgggcg agaagctgct ccggcctagc ctggcggagc 900
tccacgacga gctggaaaag gaaccttttg aggatggctt tgcaaatggg gaagaaagta 960
ctccaaccag agatgctgtg gtcacgtata ctgcagaaag taaaggagtc gtgaagtttg 1020
gctggatcaa gggtgtatta gtacgttgta tgttaaacat ttggggtgtg atgcttttca 1080
ttagattgtc atggattgtg ggtcaagctg gaataggtct atcagtcctt gtaataatga 1140
tggccactgt tgtgacaact atcacaggat tgtctacttc agcaatagca actaatggat 1200
ttgtaagagg aggaggagca tattatttaa tatctagaag tctagggcca gaatttggtg 1260
gtgcaattgg tctaatcttc gcctttgcca acgctgttgc agttgctatg tatgtggttg 1320
gatttgcaga aaccgtggtg gagttgctta aggaacattc catacttatg atagatgaaa 1380
tcaatgatat ccgaattatt ggagccatta cagtcgtgat tcttttaggt atctcagtag 1440
ctggaatgga gtgggaagca aaagctcaga ttgttctttt ggtgatccta cttcttgcta 1500
ttggtgattt cgtcatagga acatttatcc cactggagag caagaagcca aaagggtttt 1560
ttggttataa atctgaaata tttaatgaga actttgggcc cgattttcga gaggaagaga 1620
ctttcttttc tgtatttgcc atcttttttc ctgctgcaac tggtattctg gctggagcaa 1680
atatctcagg tgatcttgca gatcctcagt cagccatacc caaaggaaca ctcctagcca 1740
ttttaattac tacattggtt tacgtaggaa ttgcagtatc tgtaggttct tgtgttgttc 1800
gagatgccac tggaaacgtt aatgacacta tcgtaacaga gctaacaaac tgtacttctg 1860
cagcctgcaa attaaacttt gatttttcat cttgtgaaag cagtccttgt tcctatggcc 1920
taatgaacaa cttccaggta atgagtatgg tgtcaggatt tacaccacta atttctgcag 1980
gtatattttc agccactctt tcttcagcat tagcatccct agtgagtgct cccaaaatat 2040
ttcaggctct atgtaaggac aacatctacc cagctttcca gatgtttgct aaaggttatg 2100
ggaaaaataa tgaacctctt cgtggctaca tcttaacatt cttaattgca cttggattca 2160
tcttaattgc tgaactgaat gttattgcac caattatctc aaacttcttc cttgcatcat 2220
atgcattgat caatttttca gtattccatg catcacttgc aaaatctcca ggatggcgtc 2280
ctgcattcaa atactacaac atgtggatat cacttcttgg agcaattctt tgttgcatag 2340
taatgttcgt cattaactgg tgggctgcat tgctaacata tgtgatagtc cttgggctgt 2400
atatttatgt tacctacaaa aaaccagatg tgaattgggg atcctctaca caagccctga 2460
cttacctgaa tgcactgcag cattcaattc gtctttctgg agtggaagac cacgtgaaaa 2520
actttaggcc acagtgtctt gttatgacag gtgctccaaa ctcacgtcca gctttacttc 2580
atcttgttca tgatttcaca aaaaatgttg gtttgatgat ctgtggccat gtacatatgg 2640
gtcctcgaag acaagccatg aaagagatgt ccatcgatca agccaaatat cagcgatggc 2700
ttattaagaa caaaatgaag gcattttatg ctccagtaca tgcagatgac ttgagagaag 2760
gtgcacagta tttgatgcag gctgctggtc ttggtcgtat gaagccaaac acacttgtcc 2820
ttggatttaa gaaagattgg ttgcaagcag atatgaggga tgtggatatg tatataaact 2880
tatttcatga tgcttttgac atacaatatg gagtagtggt tattcgccta aaagaaggtc 2940
tggatatatc tcatcttcaa ggacaagaag aattattgtc atcacaagag aaatctcctg 3000
gcaccaagga tgtggtagta agtgtggaat atagtaaaaa gtccgattta gatacttcca 3060
aaccactcag tgaaaaacca attacacaca aagttgagga agaggatggc aagactgcaa 3120
ctcaaccact gttgaaaaaa gaatccaaag gccctattgt gcctttaaat gtagctgacc 3180
aaaagcttct tgaagctagt acacagtttc agaaaaaaca aggaaagaat actattgatg 3240
tctggtggct ttttgatgat ggaggtttga ccttattgat accttacctt ctgacgacca 3300
agaaaaaatg gaaagactgt aagatcagag tattcattgg tggaaagata aacagaatag 3360
accatgaccg gagagcgatg gctactttgc ttagcaagtt ccggatagac ttttctgata 3420
tcatggttct aggagatatc aataccaaac caaagaaaga aaatattata gcttttgagg 3480
aaatcattga gccatacaga cttcatgaag atgataaaga gcaagatatt gcagataaaa 3540
tgaaagaaga tgaaccatgg cgaataacag ataatgagct tgaactttat aagaccaaga 3600
cataccggca gatcaggtta aatgagttat taaaggaaca ttcaagcaca gctaatatta 3660
ttgtcatgag tctcccagtt gcacgaaaag gtgctgtgtc tagtgctctc tacatggcat 3720
ggttagaagc tctatctaag gacctaccac caatcctcct agttcgtggg aatcatcaga 3780
gtgtccttac cttctattca taaatgttct atacagtgga cagccctcca gaatggtact 3840
tcagtgccta gtgtagtaac ctgaaatctt caatgacaca ttaacatcac aatggcgaat 3900
ggtgactttt ctttcacgat ttcattaatt tgaaagcaca caggaaagct tgctccattg 3960
ataacgtgta tggagacttc ggttttagtc aattccatat ctcaatctta atggtgattc 4020
ttctctgttg aactgaagtt tgtgagagta gttttccttt gctacttgaa tagcaataaa 4080
agcgtgttaa ctttttgg 4098
<210>11
<211>3311
<212>DNA
<213>人
<400>11
tgctaatgct tttggtacaa atggatgtgg aatataattg aatattttct tgtttaaggg 60
gagcatgaag aggtgttgag gttatgtcaa gcatctggca cagctgaagg cagatggaaa 120
tatttacaag tacgcaattt gagactaaga tattgttatc attctcctat tgaagacaag 180
agcaatagta aaacacatca ggtcaggggg ttaaagacct gtgataaacc acttccgata 240
agttggaaac gtgtgtctat attttcatat ctgtatatat ataatggtaa agaaagacac 300
cttcgtaacc cgcattttcc aaagagagga atcacaggga gatgtacagc aatggggcca 360
tttaagagtt ctgtgttcat cttgattctt caccttctag aaggggccct gagtaattca 420
ctcattcagc tgaacaacaa tggctatgaa ggcattgtcg ttgcaatcga ccccaatgtg 480
ccagaagatg aaacactcat tcaacaaata aaggacatgg tgacccaggc atctctgtat 540
ctgtttgaag ctacaggaaa gcgattttat ttcaaaaatg ttgccatttt gattcctgaa 600
acatggaaga caaaggctga ctatgtgaga ccaaaacttg agacctacaa aaatgctgat 660
gttctggttg ctgagtctac tcctccaggt aatgatgaac cctacactga gcagatgggc 720
aactgtggag agaagggtga aaggatccac ctcactcctg atttcattgc aggaaaaaag 780
ttagctgaat atggaccaca aggtaaggca tttgtccatg agtgggctca tctacgatgg 840
ggagtatttg acgagtacaa taatgatgag aaattctact tatccaatgg aagaatacaa 900
gcagtaagat gttcagcagg tattactggt acaaatgtag taaagaagtg tcagggaggc 960
agctgttaca ccaaaagatg cacattcaat aaagttacag gactctatga aaaaggatgt 1020
gagtttgttc tccaatcccg ccagacggag aaggcttcta taatgtttgc acaacatgtt 1080
gattctatag ttgaattctg tacagaacaa aaccacaaca aagaagctcc aaacaagcaa 1140
aatcaaaaat gcaatctccg aagcacatgg gaagtgatcc gtgattctga ggactttaag 1200
aaaaccactc ctatgacaac acagccacca aatcccacct tctcattgct gcagattgga 1260
caaagaattg tgtgtttagt ccttgacaaa tctggaagca tggcgactgg taaccgcctc 1320
aatcgactga atcaagcagg ccagcttttc ctgctgcaga cagttgagct ggggtcctgg 1380
gttgggatgg tgacatttga cagtgctgcc catgtacaaa gtgaactcat acagataaac 1440
agtggcagtg acagggacac actcgccaaa agattacctg cagcagcttc aggagggacg 1500
tccatctgca gcgggcttcg atcggcattt actgtgatta ggaagaaata tccaactgat 1560
ggatctgaaa ttgtgctgct gacggatggg gaagacaaca ctataagtgg gtgctttaac 1620
gaggtcaaac aaagtggtgc catcatccac acagtcgctt tggggccctc tgcagctcaa 1680
gaactagagg agctgtccaa aatgacagga ggtttacaga catatgcttc agatcaagtt 1740
cagaacaatg gcctcattga tgcttttggg gccctttcat caggaaatgg agctgtctct 1800
cagcgctcca tccagcttga gagtaaggga ttaaccctcc agaacagcca gtggatgaat 1860
ggcacagtga tcgtggacag caccgtggga aaggacactt tgtttcttat cacctggaca 1920
acgcagcctc cccaaatcct tctctgggat cccagtggac agaagcaagg tggctttgta 1980
gtggacaaaa acaccaaaat ggcctacctc caaatcccag gcattgctaa ggttggcact 2040
tggaaataca gtctgcaagc aagctcacaa accttgaccc tgactgtcac gtcccgtgcg 2100
tccaatgcta ccctgcctcc aattacagtg acttccaaaa cgaacaagga caccagcaaa 2160
ttccccagcc ctctggtagt ttatgcaaat attcgccaag gagcctcccc aattctcagg 2220
gccagtgtca cagccctgat tgaatcagtg aatggaaaaa cagttacctt ggaactactg 2280
gataatggag caggtgctga tgctactaag gatgacggtg tctactcaag gtatttcaca 2340
acttatgaca cgaatggtag atacagtgta aaagtgcggg ctctgggagg agttaacgca 2400
gccagacgga gagtgatacc ccagcagagt ggagcactgt acatacctgg ctggattgag 2460
aatgatgaaa tacaatggaa tccaccaaga cctgaaatta ataaggatga tgttcaacac 2520
aagcaagtgt gtttcagcag aacatcctcg ggaggctcat ttgtggcttc tgatgtccca 2580
aatgctccca tacctgatct cttcccacct ggccaaatca ccgacctgaa ggcggaaatt 2640
cacgggggca gtctcattaa tctgacttgg acagctcctg gggatgatta tgaccatgga 2700
acagctcaca agtatatcat tcgaataagt acaagtattc ttgatctcag agacaagttc 2760
aatgaatctc ttcaagtgaa tactactgct ctcatcccaa aggaagccaa ctctgaggaa 2820
gtctttttgt ttaaaccaga aaacattact tttgaaaatg gcacagatct tttcattgct 2880
attcaggctg ttgataaggt cgatctgaaa tcagaaatat ccaacattgc acgagtatct 2940
ttgtttattc ctccacagac tccgccagag acacctagtc ctgatgaaac gtctgctcct 3000
tgtcctaata ttcatatcaa cagcaccatt cctggcattc acattttaaa aattatgtgg 3060
aagtggatag gagaactgca gctgtcaata gcctagggct gaatttttgt cagataaata 3120
aaataaatca ttcatccttt ttttgattat aaaattttct aaaatgtatt ttagacttcc 3180
tgtagggggc gatatactaa atgtatatag tacatttata ctaaatgtat tcctgtaggg 3240
ggcgatatac taaatgtatt ttagacttcc tgtagggggc gataaaataa aatgctaaac 3300
aactgggtaa a 3311
<210>12
<211>3311
<212>DNA
<213>人
<400>12
tgctaatgct tttggtacaa atggatgtgg aatataattg aatattttct tgtttaaggg 60
gagcatgaag aggtgttgag gttatgtcaa gcatctggca cagctgaagg cagatggaaa 120
tatttacaag tacgcaattt gagactaaga tattgttatc attctcctat tgaagacaag 180
agcaatagta aaacacatca ggtcaggggg ttaaagacct gtgataaacc acttccgata 240
agttggaaac gtgtgtctat attttcatat ctgtatatat ataatggtaa agaaagacac 300
cttcgtaacc cgcattttcc aaagagagga atcacaggga gatgtacagc aatggggcca 360
tttaagagtt ctgtgttcat cttgattctt caccttctag aaggggccct gagtaattca 420
ctcattcagc tgaacaacaa tggctatgaa ggcattgtcg ttgcaatcga ccccaatgtg 480
ccagaagatg aaacactcat tcaacaaata aaggacatgg tgacccaggc atctctgtat 540
ctgtttgaag ctacaggaaa gcgattttat ttcaaaaatg ttgccatttt gattcctgaa 600
acatggaaga caaaggctga ctatgtgaga ccaaaacttg agacctacaa aaatgctgat 660
gttctggttg ctgagtctac tcctccaggt aatgatgaac cctacactga gcagatgggc 720
aactgtggag agaagggtga aaggatccac ctcactcctg atttcattgc aggaaaaaag 780
ttagctgaat atggaccaca aggtaaggca tttgtccatg agtgggctca tctacgatgg 840
ggagtatttg acgagtacaa taatgatgag aaattctact tatccaatgg aagaatacaa 900
gcagtaagat gttcagcagg tattactggt acaaatgtag taaagaagtg tcagggaggc 960
agctgttaca ccaaaagatg cacattcaat aaagttacag gactctatga aaaaggatgt 1020
gagtttgttc tccaatcccg ccagacggag aaggcttcta taatgtttgc acaacatgtt 1080
gattctatag ttgaattctg tacagaacaa aaccacaaca aagaagctcc aaacaagcaa 1140
aatcaaaaat gcaatctccg aagcacatgg gaagtgatcc gtgattctga ggactttaag 1200
aaaaccactc ctatgacaac acagccacca aatcccacct tctcattgct gcagattgga 1260
caaagaattg tgtgtttagt ccttgacaaa tctggaagca tggcgactgg taaccgcctc 1320
aatcgactga atcaagcagg ccagcttttc ctgctgcaga cagttgagct ggggtcctgg 1380
gttgggatgg tgacatttga cagtgctgcc catgtacaaa gtgaactcat acagataaac 1440
agtggcagtg acagggacac actcgccaaa agattacctg cagcagcttc aggagggacg 1500
tccatctgca gcgggcttcg atcggcattt actgtgatta ggaagaaata tccaactgat 1560
ggatctgaaa ttgtgctgct gacggatggg gaagacaaca ctataagtgg gtgctttaac 1620
gaggtcaaac aaagtggtgc catcatccac acagtcgctt tggggccctc tgcagctcaa 1680
gaactagagg agctgtccaa aatgacagga ggtttacaga catatgcttc agatcaagtt 1740
cagaacaatg gcctcattga tgcttttggg gccctttcat caggaaatgg agctgtctct 1800
cagcgctcca tccagcttga gagtaaggga ttaaccctcc agaacagcca gtggatgaat 1860
ggcacagtga tcgtggacag caccgtggga aaggacactt tgtttcttat cacctggaca 1920
acgcagcctc cccaaatcct tctctgggat cccagtggac agaagcaagg tggctttgta 1980
gtggacaaaa acaccaaaat ggcctacctc caaatcccag gcattgctaa ggttggcact 2040
tggaaataca gtctgcaagc aagctcacaa accttgaccc tgactgtcac gtcccgtgcg 2100
tccaatgcta ccctgcctcc aattacagtg acttccaaaa cgaacaagga caccagcaaa 2160
ttccccagcc ctctggtagt ttatgcaaat attcgccaag gagcctcccc aattctcagg 2220
gccagtgtca cagccctgat tgaatcagtg aatggaaaaa cagttacctt ggaactactg 2280
gataatggag caggtgctga tgctactaag gatgacggtg tctactcaag gtatttcaca 2340
acttatgaca cgaatggtag atacagtgta aaagtgcggg ctctgggagg agttaacgca 2400
gccagacgga gagtgatacc ccagcagagt ggagcactgt acatacctgg ctggattgag 2460
aatgatgaaa tacaatggaa tccaccaaga cctgaaatta ataaggatga tgttcaacac 2520
aagcaagtgt gtttcagcag aacatcctcg ggaggctcat ttgtggcttc tgatgtccca 2580
aatgctccca tacctgatct cttcccacct ggccaaatca ccgacctgaa ggcggaaatt 2640
cacgggggca gtctcattaa tctgacttgg acagctcctg gggatgatta tgaccatgga 2700
acagctcaca agtatatcat tcgaataagt acaagtattc ttgatctcag agacaagttc 2760
aatgaatctc ttcaagtgaa tactactgct ctcatcccaa aggaagccaa ctctgaggaa 2820
gtctttttgt ttaaaccaga aaacattact tttgaaaatg gcacagatct tttcattgct 2880
attcaggctg ttgataaggt cgatctgaaa tcagaaatat ccaacattgc acgagtatct 2940
ttgtttattc ctccacagac tccgccagag acacctagtc ctgatgaaac gtctgctcct 3000
tgtcctaata ttcatatcaa cagcaccatt cctggcattc acattttaaa aattatgtgg 3060
aagtggatag gagaactgca gctgtcaata gcctagggct gaatttttgt cagataaata 3120
aaataaatca ttcatccttt ttttgattat aaaattttct aaaatgtatt ttagacttcc 3180
tgtagggggc gatatactaa atgtatatag tacatttata ctaaatgtat tcctgtaggg 3240
ggcgatatac taaatgtatt ttagacttcc tgtagggggc gataaaataa aatgctaaac 3300
aactgggtaa a 3311
<210>13
<211>2609
<212>DNA
<213>人
<220>
<221>misc_特征
<222>(2025)..(2025)
<223>任意碱基
<220>
<221>misc_特征
<223>任意碱基
<220>
<221>misc_特征
<222>(2164)..(2164)
<223>
<220>
<221>misc_特征
<222>(2264)..(2264)
<223>任意碱基
<400>13
gctgatagca cagttctgtc cagagaagga aggcggaata aacttattca ttcccaggaa 60
ctcttggggt aggtgtgtgt ttttcacatc ttaaaggctc acagaccctg cgctggacaa 120
atgttccatt cctgaaggac ctctccagaa tccggattgc tgaatcttcc ctgttgccta 180
gaagggctcc aaaccacctc ttgacaatgg gaaactgggt ggttaaccac tggttttcag 240
ttttgtttct ggttgtttgg ttagggctga atgttttcct gtttgtggat gccttcctga 300
aatatgagaa ggccgacaaa tactactaca caagaaaaat ccttgggtca acattggcct 360
gtgcccgagc gtctgctctc tgcttgaatt ttaacagcac gctgatcctg cttcctgtgt 420
gtcgcaatct gctgtccttc ctgaggggca cctgctcatt ttgcagccgc acactgagaa 480
agcaattgga tcacaacctc accttccaca agctggtggc ctatatgatc tgcctacata 540
cagctattca catcattgca cacctgttta actttgactg ctatagcaga agccgacagg 600
ccacagatgg ctcccttgcc tccattctct ccagcctatc tcatgatgag aaaaaggggg 660
gttcttggct aaatcccatc cagtcccgaa acacgacagt ggagtatgtg acattcacca 720
gcgttgctgg tctcactgga gtgatcatga caatagcctt gattctcatg gtaacttcag 780
ctactgagtt catccggagg agttattttg aagtcttctg gtatactcac caccttttta 840
tcttctatat ccttggctta gggattcacg gcattggtgg aattgtccgg ggtcaaacag 900
aggagagcat gaatgagagt catcctcgca agtgtgcaga gtcttttgag atgtgggatg 960
atcgtgactc ccactgtagg cgccctaagt ttgaagggca tccccctgag tcttggaagt 1020
ggatccttgc accggtcatt ctttatatct gtgaaaggat cctccggttt taccgctccc 1080
agcagaaggt tgtgattacc aaggttgtta tgcacccatc caaagttttg gaattgcaga 1140
tgaacaagcg tggcttcagc atggaagtgg ggcagtatat ctttgttaat tgcccctcaa 1200
tctctctcct ggaatggcat ccttttactt tgacctctgc tccagaggaa gatttcttct 1260
ccattcatat ccgagcagca ggggactgga cagaaaatct cataagggct ttcgaacaac 1320
aatattcacc aattcccagg attgaagtgg atggtccctt tggcacagcc agtgaggatg 1380
ttttccagta tgaagtggct gtgctggttg gagcaggaat tggggtcacc ccctttgctt 1440
ctatcttgaa atccatctgg tacaaattcc agtgtgcaga ccacaacctc aaaacaaaaa 1500
agatctattt ctactggatc tgcagggaga caggtgcctt ttcctggttc aacaacctgt 1560
tgacttccct ggaacaggag atggaggaat taggcaaagt gggttttcta aactaccgtc 1620
tcttcctcac cggatgggac agcaatattg ttggtcatgc agcattaaac tttgacaagg 1680
ccactgacat cgtgacaggt ctgaaacaga aaacctcctt tgggagacca atgtgggaca 1740
atgagttttc tacaatagct acctcccacc ccaagtctgt agtgggagtt ttcttatgtg 1800
gccctcggac tttggcaaag agcctgcgca aatgctgtca ccgatattcc agtctggatc 1860
ctagaaaggt tcaattctac ttcaacaaag aaaatttttg agttatagga ataaggacgg 1920
taatctgcat tttgtctctt tgtatcttca gtaattgagt tataggaata aggacggtaa 1980
tctgcatttt gtctctttgt atcttcagta atttacttgg tctcntcagg tttgancagt 2040
cactttagga taagaatgtg cctctcaagc cttgactccc tggtattctt tttttgattg 2100
cattcaactt cgttacttga gcttcagcaa cttaagaact tctgaagttc ttaaagttct 2160
gaanttctta aagcccatgg atcctttctc agaaaaataa ctgtaaatct ttctggacag 2220
ccatgactgt agcaaggctt gatagcagaa gtttggtggt tcanaattat acaactaatc 2280
ccaggtgatt ttatcaattc cagtgttacc atctcctgag ttttggtttg taatcttttg 2340
tccctcccac ccccacagaa gattttaagt agggtgactt tttaaataaa aatttattga 2400
ataattaatg ataaaacata ataataaaca taaataataa acaaaattac cgagaacccc 2460
atccccatat aacaccaaca gtgtacatgt ttactgtcac ttttgatatg gtttatccag 2520
tgtgaacagc aatttattat ttttgctcat caaaaaataa aggatttttt ttcacttgaa 2580
aaaaaaaaaa aaaaaaaaaa aaaaaaaaa 2609
<210>14
<211>15720
<212>DNA
<213>人
<400>14
caacccacac cgcccctgcc agccaccatg gggctgccac tagcccgcct ggcggctgtg 60
tgcctggccc tgtctttggc agggggctcg gagctccaga cagagggcag aacccgatac 120
cacggccgca acgtctgcag cacctggggc aacttccact acaagacctt cgacggggac 180
gtcttccgct tccccggcct ctgcgactac aacttcgcct ccgactgccg aggctcctac 240
aaggaatttg ctgtgcacct gaagcggggt ccgggccagg ctgaggcccc cgccggggtg 300
gagtccatcc tgctgaccat caaggatgac accatctacc tcacccgcca cctggctgtg 360
cttaacgggg ccgtggtcag caccccgcac tacagccccg ggctgctcat tgagaagagc 420
gatgcctaca ccaaagtcta ctcccgcgcc ggcctcaccc tcatgtggaa ccgggaggat 480
gcactcatgc tggagctgga cactaagttc cggaaccaca cctgtggcct ctgcggggac 540
tacaacggcc tgcagagcta ttcagaattc ctctctgacg gcgtgctctt cagtcccctg 600
gagtttggga acatgcagaa gatcaaccag cccgatgtgg tgtgtgagga tcccgaggag 660
gaggtggccc ccgcatcctg ctccgagcac cgcgccgagt gtgagaggct gctgaccgcc 720
gaggccttcg cggactgtca ggacctggtg ccgctggagc cgtatctgcg cgcctgccag 780
caggaccgct gccggtgccc gggcggtgac acctgcgtct gcagcaccgt ggccgagttc 840
tcccgccagt gctcccacgc cggcggccgg cccgggaact ggaggaccgc cacgctctgc 900
cccaagacct gccccgggaa cctggtgtac ctggagagcg gctcgccctg catggacacc 960
tgctcacacc tggaggtgag cagcctgtgc gaggagcacc gcatggacgg ctgtttctgc 1020
ccagaaggca ccgtatatga cgacatcggg gacagtggct gcgttcctgt gagccagtgc 1080
cactgcaggc tgcacggaca cctgtacaca ccgggccagg agatcaccaa tgactgcgag 1140
cagtgtgtct gtaacgctgg ccgctgggtg tgcaaagacc tgccctgccc cggcacctgt 1200
gccctggaag gcggctccca catcaccacc ttcgatggga agacgtacac cttccacggg 1260
gactgctact atgtcctggc caagggtgac cacaacgatt cctacgctct cctgggcgag 1320
ctggccccct gtggctccac agacaagcag acctgcctga agacggtggt gctgctggct 1380
gacaagaaga agaatgcggt ggtcttcaag tccgatggca gtgtactgct caaccagctg 1440
caggtgaacc tgccccacgt gaccgcgagc ttctctgtct tccgcccgtc ttcctaccac 1500
atcatggtga gcatggccat tggcgtccgg ctgcaggtgc agctggcccc agtcatgcaa 1560
ctctttgtga cactggacca ggcctcccag gggcaggtgc agggcctctg cgggaacttc 1620
aacggcctgg aaggtgacga cttcaagacg gccagcgggc tggtggaggc cacgggggcc 1680
ggctttgcca acacctggaa ggcacagtca acctgccatg acaagctgga ctggttggac 1740
gatccctgct ccctgaacat cgagagcgcc aactacgccg agcactggtg ctccctcctg 1800
aagaagacag agaccccctt tggcaggtgc cactcggctg tggaccctgc tgagtattac 1860
aagaggtgca aatatgacac gtgtaactgt cagaacaatg aggactgcct gtgcgccgcc 1920
ctgtcctcct acgcgcgcgc ctgcaccgcc aagggcgtca tgctgtgggg ctggcgggag 1980
catgtctgca acaaggatgt gggctcctgc cccaactcgc aggtcttcct gtacaacctg 2040
accacctgcc agcagacctg ccgctccctc tccgaggccg acagccactg tctcgagggc 2100
tttgcgcctg tggacggctg cggctgccct gaccacacct tcctggacga gaagggccgc 2160
tgcgtacccc tggccaagtg ctcctgttac caccgcggtc tctacctgga ggcgggggat 2220
gtggtcgtca ggcaggaaga acgatgtgtg tgccgggatg ggcggctgca ctgtaggcag 2280
atccggctga tcggccagag ctgcacggcc ccaaagatcc acatggactg cagcaacctg 2340
actgcactgg ccacctcgaa gccccgagcc ctcagctgcc agacgctggc cgccggctat 2400
taccacacag agtgtgtcag tggctgtgtg tgccccgacg ggctgatgga tgacggccgg 2460
ggtggctgcg tggtggagaa ggaatgccct tgcgtccata acaacgacct gtattcttcc 2520
ggcgccaaga tcaaggtgga ctgcaatacc tgcacctgca agagaggacg ctgggtgtgc 2580
acccaggctg tgtgccatgg cacctgctcc atttacggga gtggccacta catcaccttt 2640
gatgggaagt actacgactt tgacggacac tgctcctacg tggctgttca ggactactgc 2700
ggccagaact cctcactggg ctcattcagc atcatcaccg agaacgtccc ctgtggcact 2760
acgggcgtca cctgctccaa ggccatcaag atcttcatgg ggaggacgga gctgaagttg 2820
gaagacaagc accgtgtggt gatccagcgt gatgagggtc accacgtggc ctacaccacg 2880
cgggaggtgg gccagtacct ggtggtggag tccagcacgg gcatcatcgt catctgggac 2940
aagaggacca ccgtgttcat caagctggct ccctcctaca agggcaccgt gtgtggcctg 3000
tgtgggaact ttgaccaccg ctccaacaac gacttcacca cgcgggacca catggtggtg 3060
agcagcgagc tggacttcgg gaacagctgg aaggaggccc ccacctgccc agatgtgagc 3120
accaaccccg agccctgcag cctgaacccg caccgccgct cctgggccga gaagcagtgc 3180
agcatcctca aaagcagcgt gttcagcatc tgccacagca aggtggaccc caagcccttc 3240
tacgaggcct gtgtgcacga ctcgtgctcc tgtgacacgg gtggggactg tgagtgcttc 3300
tgctctgccg tggcctccta cgcccaggag tgtaccaaag agggggcctg cgtgttctgg 3360
aggacgccgg acctgtgccc catattctgc gactactaca accctccgca tgagtgtgag 3420
tggcactatg agccatgtgg gaaccggagc ttcgagacct gcaggaccat caacggcatc 3480
cactccaaca tctccgtgtc ctacctggag ggctgctacc cccggtgccc caaggacagg 3540
cccatctatg aggaggatct gaagaagtgt gtcactgcag acaagtgtgg ctgctatgtc 3600
gaggacaccc actacccacc tggagcatcg gttcccaccg aggagacctg caagtcctgc 3660
gtgtgtacca actcctccca agtcgtctgc aggccggagg aaggaaagat tcttaaccag 3720
acccaggatg gcgccttctg ctactgggag atctgtggcc ccaacgggac ggtggagaag 3780
cacttcaaca tctgttccat tacgacacgc ccgtccaccc tgaccacctt caccaccatc 3840
accctcccca ccacccccac ctccttcacc actaccacca ccaccaccac cccgacctcc 3900
agcacagttt tatcaacaac tccgaagctg tgctgcctct ggtctgactg gatcaatgag 3960
gaccacccca gcagtggcag cgacgacggt gaccgagaac catttgatgg ggtctgcggg 4020
gcccctgagg acatcgagtg caggtcggtc aaggatcccc acctcagctt ggagcagcat 4080
ggccagaagg tgcagtgtga tgtctctgtt gggttcattt gcaagaatga agaccagttt 4140
ggaaatggac catttggact gtgttacgac tacaagatac gtgtcaattg ttgctggccc 4200
atggataagt gtatcaccac tcccagccct ccaactacca ctcccagccc tccaccaacc 4260
acgacgacca cccttccacc aaccaccacc cccagccctc caaccaccac cacaaccacc 4320
cctccaccaa ccaccacccc cagccctcca ataaccacca cgaccacccc tctaccaacc 4380
accactccca gccctccaat aagcaccaca accacccctc caccaaccac cactcccagc 4440
cctccaacca ccactcccag ccctccaacc accactccca gccctccaac aaccaccaca 4500
accacccctc caccaaccac cactcccagc cctccaatga ctacgcccat cactccacca 4560
gccagcacta ccacccttcc accaaccacc actcccagcc ctccaacaac caccacaacc 4620
acccctccac caaccaccac tcccagtcct ccaacgacta cgcccatcac tccaccaacc 4680
agcactacta cccttccacc aaccaccact cccagccctc caccaaccac cacaaccacc 4740
cctccaccaa ccaccactcc cagccctcca acaaccacca ctcccagtcc tccaacaatc 4800
accacaacca cccctccacc aaccaccact cccagccctc caacaacgac cacaaccacc 4860
cctccaccaa ccaccactcc cagccctcca acgactacac ccatcactcc accaaccagc 4920
actaccaccc ttccaccaac caccactccc agccctccac caaccaccac aaccacccct 4980
ccaccaacca ccactcccag ccctccaaca accaccactc ccagccctcc aataaccacc 5040
acaaccaccc ctccaccaac caccactccc agctctccaa taaccaccac tcccagccct 5100
ccaacaacca ccatgaccac cccttcacca accaccaccc ccagctctcc aataaccacc 5160
acaaccaccc cttcctcaac taccactccc agccctccac caaccaccat gaccacccct 5220
tcaccaacca ccactcccag ccctccaaca accaccatga ccacccttcc accaaccacc 5280
acttccagcc ctctaacaac tactcctcta cctccatcaa taactcctcc tacattttca 5340
ccattctcaa cgacaacccc tactacccca tgcgtgcctc tctgcaattg gactggctgg 5400
ctggattctg gaaaacccaa ctttcacaaa ccaggtggag acacagaatt gattggagac 5460
gtctgtggac caggctgggc agctaacatc tcttgcagag ccaccatgta tcctgatgtt 5520
cccattggac agcttggaca aacagtggtg tgtgatgtct ctgtggggct gatatgcaaa 5580
aatgaagacc aaaagccagg tggggtcatc cctatggcct tctgcctcaa ctacgagatc 5640
aacgttcagt gctgtgagtg tgtcacccaa cccaccacca tgacaaccac caccacagag 5700
aacccaactc cgccaaccac gacacccatc accaccacca ctacggtgac cccaacccca 5760
acacccaccg gcacacagac cccaaccacg acacccatca ccaccaccac tacggtgacc 5820
ccaaccccaa cacccaccgg cacacagacc ccaaccacga cacccatcac caccaccact 5880
acggtgaccc caaccccaac acccaccggc acacagaccc caaccacgac acccatcacc 5940
accaccacta cggtgacccc aaccccaaca cccaccggca cacagacccc aaccacgaca 6000
cccatcacca ccaccactac ggtgacccca accccaacac ccaccggcac acagacccca 6060
accacgacac ccatcaccac caccactacg gtgaccccaa ccccaacacc caccggcaca 6120
cagaccccaa ccacgacacc catcaccacc accactacgg tgaccccaac cccaacaccc 6180
accggcacac agaccccaac cacgacaccc atcaccacca ccactacggt gaccccaacc 6240
ccaacaccca ccggcacaca gaccccaacc acgacaccca tcaccaccac cactacggtg 6300
accccaaccc caacacccac cggcacacag accccaacca cgacacccat caccaccacc 6360
actacggtga ccccaacccc aacacccacc ggcacacaga ccccaaccac gacacccatc 6420
accaccacca ctacggtgac cccaacccca acacccaccg gcacacagac cccaaccacg 6480
acacccatca ccaccaccac tacggtgacc ccaaccccaa cacccaccgg cacacagacc 6540
ccaaccacga cacccatcac caccaccact acggtgaccc caaccccaac acccaccggc 6600
acacagaccc caaccacgac acccatcacc accaccacta cggtgacccc aaccccaaca 6660
cccaccggca cacagacccc aaccacgaca cccatcacca ccaccactac ggtgacccca 6720
accccaacac ccaccggcac acagacccca accacgacac ccatcaccac caccactacg 6780
gtgaccccaa ccccaacacc caccggcaca cagaccccaa ccacgacacc catcaccacc 6840
accactacgg tgaccccaac cccaacaccc accggcacac agaccccaac cacgacaccc 6900
atcaccacca ccactacggt gaccccaacc ccaacaccca ccggcacaca gaccccaacc 6960
acgacaccca tcaccaccac cactacggtg accccaaccc caacacccac cggcacacag 7020
accccaacca cgacacccat caccaccacc actacggtga ccccaacccc aacacccacc 7080
ggcacacaga ccccaaccac gacacccatc accaccacca ctacggtgac cccaacccca 7140
acacccaccg gcacacagac cccaaccacg acacccatca ccaccaccac tacggtgacc 7200
ccaaccccaa cacccaccgg cacacagacc ccaaccacga cacccatcac caccaccact 7260
acggtgaccc caaccccaac acccaccggc acacagaccc caaccacgac acccatcacc 7320
accaccacta cggtgacccc aaccccaaca cccaccggca cacagacccc aaccacgaca 7380
cccatcacca ccaccactac ggtgacccca accccaacac ccaccggcac acagacccca 7440
accacgacac ccatcaccac caccactacg gtgaccccaa ccccaacacc caccggcaca 7500
cagaccccaa ccacgacacc catcaccacc accactacgg tgaccccaac cccaacaccc 7560
accggcacac agaccccaac cacgacaccc atcaccacca ccactacggt gaccccaacc 7620
ccaacaccca ccggcacaca gaccccaacc acgacaccca tcaccaccac cactacggtg 7680
accccaaccc caacacccac cggcacacag accccaacca cgacacccat caccaccacc 7740
actacggtga ccccaacccc aacacccacc ggcacacaga ccccaaccac gacacccatc 7800
accaccacca ctacggtgac cccaacccca acacccaccg gcacacagac cccaaccacg 7860
acacccatca ccaccaccac tacggtgacc ccaaccccaa cacccaccgg cacacagacc 7920
ccaaccacga cacccatcac caccaccact acggtgaccc caaccccaac acccaccggc 7980
acacagaccc caaccacgac acccatcacc accaccacta cggtgacccc aaccccaaca 8040
cccaccggca cacagacccc aaccacgaca cccatcacca ccaccactac ggtgacccca 8100
accccaacac ccaccggcac acagacccca accacgacac ccatcaccac caccactacg 8160
gtgaccccaa ccccaacacc caccggcaca cagaccccaa ccacgacacc catcaccacc 8220
accactacgg tgaccccaac cccaacaccc accggcacac agaccccaac cacgacaccc 8280
atcaccacca ccactacggt gaccccaacc ccaacaccca ccggcacaca gaccccaacc 8340
acgacaccca tcaccaccac cactacggtg accccaaccc caacacccac cggcacacag 8400
accccaacca cgacacccat caccaccacc actacggtga ccccaacccc aacacccacc 8460
ggcacacaga ccccaaccac gacacccatc accaccacca ctacggtgac cccaacccca 8520
acacccaccg gcacacagac cccaaccacg acacccatca ccaccaccac tacggtgacc 8580
ccaaccccaa cacccaccgg cacacagacc ccaaccacga cacccatcac caccaccact 8640
acggtgaccc caaccccaac acccaccggc acacagaccc caaccacgac acccatcacc 8700
accaccacta cggtgacccc aaccccaaca cccaccggca cacagacccc aaccacgaca 8760
cccatcacca ccaccactac ggtgacccca accccaacac ccaccggcac acagacccca 8820
accacgacac ccatcaccac caccactacg gtgaccccaa ccccaacacc caccggcaca 8880
cagaccccaa ccacgacacc catcaccacc accactacgg tgaccccaac cccaacaccc 8940
accggcacac agaccccaac cacgacaccc atcaccacca ccactacggt gaccccaacc 9000
ccaacaccca ccggcacaca gaccccaacc acgacaccca tcaccaccac cactacggtg 9060
accccaaccc caacacccac cggcacacag accccaacca cgacacccat caccaccacc 9120
actacggtga ccccaacccc aacacccacc ggcacacaga ccccaaccac gacacccatc 9180
accaccacca ctacggtgac cccaacccca acacccaccg gcacacagac cccaaccacg 9240
acacccatca ccaccaccac tacggtgacc ccaaccccaa cacccaccgg cacacagacc 9300
ccaaccacga cacccatcac caccaccact acggtgaccc caaccccaac acccaccggc 9360
acacagaccc caaccacgac acccatcacc accaccacta cggtgacccc aaccccaaca 9420
cccaccggca cacagacccc aaccacgaca cccatcacca ccaccactac ggtgacccca 9480
accccaacac ccaccggcac acagacccca accacgacac ccatcaccac caccactacg 9540
gtgaccccaa ccccaacacc caccggcaca cagaccccaa ccacgacacc catcaccacc 9600
accactacgg tgaccccaac cccaacaccc accggcacac agaccccaac cacgacaccc 9660
atcaccacca ccactacggt gaccccaacc ccaacaccca ccggcacaca gaccccaacc 9720
acgacaccca tcaccaccac cactacggtg accccaaccc caacacccac cggcacacag 9780
accccaacca cgacacccat caccaccacc actacggtga ccccaacccc aacacccacc 9840
ggcacacaga ccccaaccac gacacccatc accaccacca ctacggtgac cccaacccca 9900
acacccaccg gcacacagac cccaaccacg acacccatca ccaccaccac tacggtgacc 9960
ccaaccccaa cacccaccgg cacacagacc ccaaccacga cacccatcac caccaccact 10020
acggtgaccc caaccccaac acccaccggc acacagaccc caaccacgac acccatcacc 10080
accaccacta cggtgacccc aaccccaaca cccaccggca cacagacccc aaccacgaca 10140
cccatcacca ccaccactac ggtgacccca accccaacac ccaccggcac acagacccca 10200
accacgacac ccatcaccac caccactacg gtgaccccaa ccccaacacc caccggcaca 10260
cagaccccaa ccacgacacc catcaccacc accactacgg tgaccccaac cccaacaccc 10320
accggcacac agaccccaac cacgacaccc atcaccacca ccactacggt gaccccaacc 10380
ccaacaccca ccggcacaca gaccccaacc acgacaccca tcaccaccac cactacggtg 10440
accccaaccc caacacccac cggcacacag accccaacca cgacacccat caccaccacc 10500
actacggtga ccccaacccc aacacccacc ggcacacaga ccccaaccac gacacccatc 10560
accaccacca ctacggtgac cccaacccca acacccaccg gcacacagac cccaaccacg 10620
acacccatca ccaccaccac tacggtgacc ccaaccccaa cacccaccgg cacacagacc 10680
ccaaccacga cacccatcac caccaccact acggtgaccc caaccccaac acccaccggc 10740
acacagaccc caaccacgac acccatcacc accaccacta cggtgacccc aaccccaaca 10800
cccaccggca cacagacccc aaccacgaca cccatcacca ccaccactac ggtgacccca 10860
accccaacac ccaccggcac acagacccca accacgacac ccatcaccac caccactacg 10920
gtgaccccaa ccccaacacc caccggcaca cagaccccaa ccacgacacc catcaccacc 10980
accactacgg tgaccccaac cccaacaccc accggcacac agaccccaac cacgacaccc 11040
atcaccacca ccactacggt gaccccaacc ccaacaccca ccggcacaca gaccccaacc 11100
acgacaccca tcaccaccac cactacggtg accccaaccc caacacccac cggcacacag 11160
accccaacca cgacacccat caccaccacc actacggtga ccccaacccc aacacccacc 11220
ggcacacaga ccccaaccac gacacccatc accaccacca ctacggtgac cccaacccca 11280
acacccaccg gcacacagac cccaaccacg acacccatca ccaccaccac tacggtgacc 11340
ccaaccccaa cacccaccgg cacacagacc ccaaccacga cacccatcac caccaccact 11400
acggtgaccc caaccccaac acccaccggc acacagaccc caaccacgac acccatcacc 11460
accaccacta cggtgacccc aaccccaaca cccaccggca cacagacccc aaccacgaca 11520
cccatcacca ccaccactac ggtgacccca accccaacac ccaccggcac acagacccca 11580
accacgacac ccatcaccac caccactacg gtgaccccaa ccccaacacc caccggcaca 11640
cagaccccaa ccacgacacc catcaccacc accactacgg tgaccccaac cccaacaccc 11700
accggcacac agaccccaac cacgacaccc atcaccacca ccactacggt gaccccaacc 11760
ccaacaccca ccggcacaca gaccccaacc acgacaccca tcaccaccac cactacggtg 11820
accccaaccc caacacccac cggcacacag accccaacca cgacacccat caccaccacc 11880
actacggtga ccccaacccc aacacccacc ggcacacaga ccccaaccac gacacccatc 11940
accaccacca ctacggtgac cccaacccca acacccaccg gcacacagac cccaaccacg 12000
acacccatca ccaccaccac tacggtgacc ccaaccccaa cacccaccgg cacacagacc 12060
ccaaccacga cacccatcac caccaccact acggtgaccc caaccccaac acccaccggc 12120
acacagaccc caaccacgac acccatcacc accaccacta cggtgacccc aaccccaaca 12180
cccaccggca cacagacccc aaccacgaca cccatcacca ccaccactac ggtgacccca 12240
accccaacac ccaccggcac acagacccca accacgacac ccatcaccac caccactacg 12300
gtgaccccaa ccccaacacc caccggcaca cagaccccaa ccacgacacc catcaccacc 12360
accactacgg tgaccccaac cccaacaccc accggcacac agaccccaac cacgacaccc 12420
atcaccacca ccactacggt gaccccaacc ccaacaccca ccggcacaca gaccccaacc 12480
acgacaccca tcaccaccac cactacggtg accccaaccc caacacccac cggcacacag 12540
accccaacca cgacacccat caccaccacc actacggtga ccccaacccc aacacccacc 12600
ggcacacaga ccgggccccc cacccacaca agcacagcac cgattgctga gttgaccaca 12660
tccaatcctc cgcctgagtc ctcaacccct cagacctctc ggtccacctc ttcccctctc 12720
acggagtcaa ccacccttct gagtacccta ccacctgcca ttgagatgac cagcacggcc 12780
ccaccctcca cacccacggc acccacgacc acgagcggag gccacacact gtctccaccg 12840
cccagcacca ccacgtcccc tccaggcacc cccactcgcg gtaccacgac cgggtcatct 12900
tcagccccca cccccagcac tgtgcagacg accaccacca gtgcctggac cccaacgccg 12960
accccactct ccacacccag catcatcagg accacaggcc tgaggcccta cccttcctct 13020
gtgcttatct gctgtgtcct gaacgacacc tactacgcac caggtgagga ggtgtacaac 13080
ggcacatacg gagacacctg ttatttcgtc aactgctcac tgagctgtac gttggagttc 13140
tataactggt cctgcccatc cacgccctcc ccaacaccca cgccctccaa gtcgacgccc 13200
acgccttcca agccatcgtc cacgccctcc aagccgacgc ccggcaccaa gccccccgag 13260
tgcccagact ttgatcctcc cagacaggag aacgagactt ggtggctgtg cgactgcttc 13320
atggccacgt gcaagtacaa caacacggtg gagatcgtga aggtggagtg tgagccgccg 13380
cccatgccca cctgctccaa cggcctccaa cccgtgcgcg tcgaggaccc cgacggctgc 13440
tgctggcact gggagtgcga ctgctactgc acgggctggg gcgacccgca ctatgtcacc 13500
ttcgacggac tctactacag ctaccagggc aactgcacct acgtgctggt ggaggagatc 13560
agcccctccg tggacaactt cggagtttac atcgacaact accactgcga tcccaacgac 13620
aaggtgtcct gtccccgcac cctcatcgtg cgccacgaga cccaggaggt gctgatcaag 13680
accgtgcata tgatgcccat gcaggtgcag gtgcaggtga acaggcaggc ggtggcactg 13740
ccctacaaga agtacgggct ggaggtgtac cagtctggca tcaactacgt ggtggacatc 13800
cccgagctgg gtgtcctcgt ctcctacaat ggcctgtcct tctccgtcag gctgccctac 13860
caccggtttg gcaacaacac caagggccag tgtggcacct gcaccaacac cacctccgac 13920
gactgcattc tgcccagcgg ggagatcgtc tccaactgtg aggctgcggc tgaccagtgg 13980
ctggtgaacg acccctccaa gccacactgc ccccacagca gctccacgac caagcgcccg 14040
gccgtcactg tgcccggggg cggtaaaacg accccacaca aggactgcac cccatctccc 14100
ctctgccagc tcatcaagga cagcctgttt gcccagtgcc acgcactggt gcccccgcag 14160
cactactacg atgcctgcgt gttcgacagc tgcttcatgc cgggctcgag cctggagtgc 14220
gccagtctgc aggcctacgc agccctctgt gcccagcaga acatctgcct cgactggcgg 14280
aaccacacgc atggggcctg cttggtggag tgcccatctc acagggagta ccaggcctgt 14340
ggccctgcag aagagcccac gtgcaaatcc agctcctccc agcagaacaa cacagtcctg 14400
gtggaaggct gcttctgtcc tgagggcacc atgaactacg ctcctggctt tgatgtctgc 14460
gtgaagacct gcggctgtgt gggacctgac aatgtgccca gagagtttgg ggagcacttc 14520
gagttcgact gcaagaactg tgtctgcctg gagggtggaa gtggcatcat ctgccaaccc 14580
aagaggtgca gccagaagcc cgttacccac tgcgtggaag acggcaccta cctcgccacg 14640
gaggtcaacc ctgccgacac ctgctgcaac attaccgtct gcaagtgcaa caccagcctg 14700
tgcaaagaga agccctccgt gtgcccgctg ggattcgaag tgaagagcaa gatggtgcct 14760
ggaaggtgct gtcccttcta ctggtgtgag tccaaggggg tgtgtgttca cgggaatgct 14820
gagtaccagc ccggttctcc agtttattcc tccaagtgcc aggactgcgt gtgcacggac 14880
aaggtggaca acaacaccct gctcaacgtc atcgcctgca cccacgtgcc ctgcaacacc 14940
tcctgcagcc ctggcttcga actcatggag gcccccgggg agtgctgtaa gaagtgtgaa 15000
cagacgcact gtatcatcaa acggcccgac aaccagcacg tcatcctgaa gcccggggac 15060
ttcaagagcg acccgaagaa caactgcaca ttcttcagct gcgtgaagat ccacaaccag 15120
ctcatctcgt ccgtctccaa catcacctgc cccaactttg atgccagcat ttgcatcccg 15180
ggctccatca cattcatgcc caatggatgc tgcaagacct gcacccctcg caatgagacc 15240
agggtgccct gctccaccgt ccccgtcacc acggaggttt cgtacgccgg ctgcaccaag 15300
accgtcctca tgaatcattg ctccgggtcc tgcgggacat ttgtcatgta ctcggccaag 15360
gcccaggccc tggaccacag ctgctcctgc tgcaaagagg agaaaaccag ccagcgtgag 15420
gtggtcctga gctgccccaa tggcggctcg ctgacacaca cctacaccca catcgagagc 15480
tgccagtgcc aggacaccgt ctgcgggctc cccaccggca cctcccgccg ggcccggcgc 15540
tcccctaggc atctggggag cgggtgagcg gggtgggcac agcccccttc actgccctcg 15600
acagctttac ctcccccgga ccctctgagc ctcctaagct cggcttcctc tcttcagata 15660
tttattgtct gagtctttgt tcagtccttg ctttccaata ataaactcag ggggacatgc 15720
<210>15
<211>3697
<212>DNA
<213>人
<400>15
agggagtgtt cccgggggag atactccagt cgtagcaaga gtctcgacca ctgaatggaa 60
gaaaaggact tttaaccacc attttgtgac ttacagaaag gaatttgaat aaagaaaact 120
atgatacttc aggcccatct tcactccctg tgtcttctta tgctttattt ggcaactgga 180
tatggccaag aggggaagtt tagtggaccc ctgaaaccca tgacattttc tatttatgaa 240
ggccaagaac cgagtcaaat tatattccag tttaaggcca atcctcctgc tgtgactttt 300
gaactaactg gggagacaga caacatattt gtgatagaac gggagggact tctgtattac 360
aacagagcct tggacaggga aacaagatct actcacaatc tccaggttgc agccctggac 420
gctaatggaa ttatagtgga gggtccagtc cctatcacca tagaagtgaa ggacatcaac 480
gacaatcgac ccacgtttct ccagtcaaag tacgaaggct cagtaaggca gaactctcgc 540
ccaggaaagc ccttcttgta tgtcaatgcc acagacctgg atgatccggc cactcccaat 600
ggccagcttt attaccagat tgtcatccag cttcccatga tcaacaatgt catgtacttt 660
cagatcaaca acaaaacggg agccatctct cttacccgag agggatctca ggaattgaat 720
cctgctaaga atccttccta taatctggtg atctcagtga aggacatggg aggccagagt 780
gagaattcct tcagtgatac cacatctgtg gatatcatag tgacagagaa tatttggaaa 840
gcaccaaaac ctgtggagat ggtggaaaac tcaactgatc ctcaccccat caaaatcact 900
caggtgcggt ggaatgatcc cggtgcacaa tattccttag ttgacaaaga gaagctgcca 960
agattcccat tttcaattga ccaggaagga gatatttacg tgactcagcc cttggaccga 1020
gaagaaaagg atgcatatgt tttttatgca gttgcaaagg atgagtacgg aaaaccactt 1080
tcatatccgc tggaaattca tgtaaaagtt aaagatatta atgataatcc acctacatgt 1140
ccgtcaccag taaccgtatt tgaggtccag gagaatgaac gactgggtaa cagtatcggg 1200
acccttactg cacatgacag ggatgaagaa aatactgcca acagttttct aaactacagg 1260
attgtggagc aaactcccaa acttcccatg gatggactct tcctaatcca aacctatgct 1320
ggaatgttac agttagctaa acagtccttg aagaagcaag atactcctca gtacaactta 1380
acgatagagg tgtctgacaa agatttcaag accctttgtt ttgtgcaaat caacgttatt 1440
gatatcaatg atcagatccc catctttgaa aaatcagatt atggaaacct gactcttgct 1500
gaagacacaa acattgggtc caccatctta accatccagg ccactgatgc tgatgagcca 1560
tttactggga gttctaaaat tctgtatcat atcataaagg gagacagtga gggacgcctg 1620
ggggttgaca cagatcccca taccaacacc ggatatgtca taattaaaaa gcctcttgat 1680
tttgaaacag cagctgtttc caacattgtg ttcaaagcag aaaatcctga gcctctagtg 1740
tttggtgtga agtacaatgc aagttctttt gccaagttca cgcttattgt gacagatgtg 1800
aatgaagcac ctcaattttc ccaacacgta ttccaagcga aagtcagtga ggatgtagct 1860
ataggcacta aagtgggcaa tgtgactgcc aaggatccag aaggtctgga cataagctat 1920
tcactgaggg gagacacaag aggttggctt aaaattgacc acgtgactgg tgagatcttt 1980
agtgtggctc cattggacag agaagccgga agtccatatc gggtacaagt ggtggccaca 2040
gaagtagggg ggtcttcctt gagctctgtg tcagagttcc acctgatcct tatggatgtg 2100
aatgacaacc ctcccaggct agccaaggac tacacgggct tgttcttctg ccatcccctc 2160
agtgcacctg gaagtctcat tttcgaggct actgatgatg atcagcactt atttcggggt 2220
ccccatttta cattttccct cggcagtgga agcttacaaa acgactggga agtttccaaa 2280
atcaatggta ctcatgcccg actgtctacc aggcacacag agtttgagga gagggagtat 2340
gtcgtcttga tccgcatcaa tgatgggggt cggccaccct tggaaggcat tgtttcttta 2400
ccagttacat tctgcagttg tgtggaagga agttgtttcc ggccagcagg tcaccagact 2460
gggataccca ctgtgggcat ggcagttggt atactgctga ccacccttct ggtgattggt 2520
ataattttag cagttgtgtt tatccgcata aagaaggata aaggcaaaga taatgttgaa 2580
agtgctcaag catctgaagt caaacctctg agaagctgaa tttgaaaagg aatgtttgaa 2640
tttatatagc aagtgctatt tcagcaacaa ccatctcatc ctattacttt tcatctaacg 2700
tgcattataa ttttttaaac agatattccc tcttgtcctt taatatttgc taaatatttc 2760
ttttttgagg tggagtcttg ctctgtcgcc caggctggag tacagtggtg tgatcccagc 2820
tcactgcaac ctccgcctcc tgggttcaca tgattctcct gcctcagctt cctaagtagc 2880
tgggtttaca ggcacccacc accatgccca gctaattttt gtatttttaa tagagacggg 2940
gtttcgccat ttggccaggc tggtcttgaa ctcctgacgt caagtgatct gcctgccttg 3000
gtctcccaat acaggcatga accactgcac ccacctactt agatatttca tgtgctatag 3060
acattagaga gatttttcat ttttccatga catttttcct ctctgcaaat ggcttagcta 3120
cttgtgtttt tcccttttgg ggcaagacag actcattaaa tattctgtac attttttctt 3180
tatcaaggag atatatcagt gttgtctcat agaactgcct ggattccatt tatgtttttt 3240
ctgattccat cctgtgtccc cttcatcctt gactcctttg gtatttcact gaatttcaaa 3300
catttgtcag agaagaaaaa cgtgaggact caggaaaaat aaataaataa aagaacagcc 3360
ttttccctta gtattaacag aaatgtttct gtgtcattaa ccatctttaa tcaatgtgac 3420
atgttgctct ttggctgaaa ttcttcaact tggaaatgac acagacccac agaaggtgtt 3480
caaacacaac ctactctgca aaccttggta aaggaaccag tcagctggcc agatttcctc 3540
actacctgcc atgcatacat gctgcgcatg ttttcttcat tcgtatgtta gtaaagtttt 3600
ggttattata tatttaacat gtggaagaaa acaagacatg aaaagagtgg tgacaaatca 3660
agaataaaca ctggttgtag tcagttttgt ttgttaa 3697
<210>16
<211>3697
<212>DNA
<213>人
<400>16
agggagtgtt cccgggggag atactccagt cgtagcaaga gtctcgacca ctgaatggaa 60
gaaaaggact tttaaccacc attttgtgac ttacagaaag gaatttgaat aaagaaaact 120
atgatacttc aggcccatct tcactccctg tgtcttctta tgctttattt ggcaactgga 180
tatggccaag aggggaagtt tagtggaccc ctgaaaccca tgacattttc tatttatgaa 240
ggccaagaac cgagtcaaat tatattccag tttaaggcca atcctcctgc tgtgactttt 300
gaactaactg gggagacaga caacatattt gtgatagaac gggagggact tctgtattac 360
aacagagcct tggacaggga aacaagatct actcacaatc tccaggttgc agccctggac 420
gctaatggaa ttatagtgga gggtccagtc cctatcacca tagaagtgaa ggacatcaac 480
gacaatcgac ccacgtttct ccagtcaaag tacgaaggct cagtaaggca gaactctcgc 540
ccaggaaagc ccttcttgta tgtcaatgcc acagacctgg atgatccggc cactcccaat 600
ggccagcttt attaccagat tgtcatccag cttcccatga tcaacaatgt catgtacttt 660
cagatcaaca acaaaacggg agccatctct cttacccgag agggatctca ggaattgaat 720
cctgctaaga atccttccta taatctggtg atctcagtga aggacatggg aggccagagt 780
gagaattcct tcagtgatac cacatctgtg gatatcatag tgacagagaa tatttggaaa 840
gcaccaaaac ctgtggagat ggtggaaaac tcaactgatc ctcaccccat caaaatcact 900
caggtgcggt ggaatgatcc cggtgcacaa tattccttag ttgacaaaga gaagctgcca 960
agattcccat tttcaattga ccaggaagga gatatttacg tgactcagcc cttggaccga 1020
gaagaaaagg atgcatatgt tttttatgca gttgcaaagg atgagtacgg aaaaccactt 1080
tcatatccgc tggaaattca tgtaaaagtt aaagatatta atgataatcc acctacatgt 1140
ccgtcaccag taaccgtatt tgaggtccag gagaatgaac gactgggtaa cagtatcggg 1200
acccttactg cacatgacag ggatgaagaa aatactgcca acagttttct aaactacagg 1260
attgtggagc aaactcccaa acttcccatg gatggactct tcctaatcca aacctatgct 1320
ggaatgttac agttagctaa acagtccttg aagaagcaag atactcctca gtacaactta 1380
acgatagagg tgtctgacaa agatttcaag accctttgtt ttgtgcaaat caacgttatt 1440
gatatcaatg atcagatccc catctttgaa aaatcagatt atggaaacct gactcttgct 1500
gaagacacaa acattgggtc caccatctta accatccagg ccactgatgc tgatgagcca 1560
tttactggga gttctaaaat tctgtatcat atcataaagg gagacagtga gggacgcctg 1620
ggggttgaca cagatcccca taccaacacc ggatatgtca taattaaaaa gcctcttgat 1680
tttgaaacag cagctgtttc caacattgtg ttcaaagcag aaaatcctga gcctctagtg 1740
tttggtgtga agtacaatgc aagttctttt gccaagttca cgcttattgt gacagatgtg 1800
aatgaagcac ctcaattttc ccaacacgta ttccaagcga aagtcagtga ggatgtagct 1860
ataggcacta aagtgggcaa tgtgactgcc aaggatccag aaggtctgga cataagctat 1920
tcactgaggg gagacacaag aggttggctt aaaattgacc acgtgactgg tgagatcttt 1980
agtgtggctc cattggacag agaagccgga agtccatatc gggtacaagt ggtggccaca 2040
gaagtagggg ggtcttcctt gagctctgtg tcagagttcc acctgatcct tatggatgtg 2100
aatgacaacc ctcccaggct agccaaggac tacacgggct tgttcttctg ccatcccctc 2160
agtgcacctg gaagtctcat tttcgaggct actgatgatg atcagcactt atttcggggt 2220
ccccatttta cattttccct cggcagtgga agcttacaaa acgactggga agtttccaaa 2280
atcaatggta ctcatgcccg actgtctacc aggcacacag agtttgagga gagggagtat 2340
gtcgtcttga tccgcatcaa tgatgggggt cggccaccct tggaaggcat tgtttcttta 2400
ccagttacat tctgcagttg tgtggaagga agttgtttcc ggccagcagg tcaccagact 2460
gggataccca ctgtgggcat ggcagttggt atactgctga ccacccttct ggtgattggt 2520
ataattttag cagttgtgtt tatccgcata aagaaggata aaggcaaaga taatgttgaa 2580
agtgctcaag catctgaagt caaacctctg agaagctgaa tttgaaaagg aatgtttgaa 2640
tttatatagc aagtgctatt tcagcaacaa ccatctcatc ctattacttt tcatctaacg 2700
tgcattataa ttttttaaac agatattccc tcttgtcctt taatatttgc taaatatttc 2760
ttttttgagg tggagtcttg ctctgtcgcc caggctggag tacagtggtg tgatcccagc 2820
tcactgcaac ctccgcctcc tgggttcaca tgattctcct gcctcagctt cctaagtagc 2880
tgggtttaca ggcacccacc accatgccca gctaattttt gtatttttaa tagagacggg 2940
gtttcgccat ttggccaggc tggtcttgaa ctcctgacgt caagtgatct gcctgccttg 3000
gtctcccaat acaggcatga accactgcac ccacctactt agatatttca tgtgctatag 3060
acattagaga gatttttcat ttttccatga catttttcct ctctgcaaat ggcttagcta 3120
cttgtgtttt tcccttttgg ggcaagacag actcattaaa tattctgtac attttttctt 3180
tatcaaggag atatatcagt gttgtctcat agaactgcct ggattccatt tatgtttttt 3240
ctgattccat cctgtgtccc cttcatcctt gactcctttg gtatttcact gaatttcaaa 3300
catttgtcag agaagaaaaa cgtgaggact caggaaaaat aaataaataa aagaacagcc 3360
ttttccctta gtattaacag aaatgtttct gtgtcattaa ccatctttaa tcaatgtgac 3420
atgttgctct ttggctgaaa ttcttcaact tggaaatgac acagacccac agaaggtgtt 3480
caaacacaac ctactctgca aaccttggta aaggaaccag tcagctggcc agatttcctc 3540
actacctgcc atgcatacat gctgcgcatg ttttcttcat tcgtatgtta gtaaagtttt 3600
ggttattata tatttaacat gtggaagaaa acaagacatg aaaagagtgg tgacaaatca 3660
agaataaaca ctggttgtag tcagttttgt ttgttaa 3697
<210>17
<211>1597
<212>DNA
<213>人
<400>17
aacaaactgc acccactgaa ctccgcagct agcatccaaa tcagcccttg agatttgagg 60
ccttggagac tcaggagttt tgagagcaaa atgacaacac ccagaaattc agtaaatggg 120
actttcctgg cagagccaat gaaaggccct attgctatgc aatctggtcc aaaaccactc 180
ttcaggagga tgtcttcact ggtgggcccc acgcaaagct tcttcatgag ggaatctaag 240
actttggggg ctgtccagat tatgaatggg ctcttccaca ttgccctggg gggtcttctg 300
atgatcccag cagggatcta tgcacccatc tgtgtgactg tgtggtaccc tctctgggga 360
ggcattatgt atattatttc cggatcactc ctggcagcaa cggagaaaaa ctccaggaag 420
tgtttggtca aaggaaaaat gataatgaat tcattgagcc tctttgctgc catttctgga 480
atgattcttt caatcatgga catacttaat attaaaattt cccatttttt aaaaatggag 540
agtctgaatt ttattagagc tcacacacca tatattaaca tatacaactg tgaaccagct 600
aatccctctg agaaaaactc cccatctacc caatactgtt acagcataca atctctgttc 660
ttgggcattt tgtcagtgat gctgatcttt gccttcttcc aggaacttgt aatagctggc 720
atcgttgaga atgaatggaa aagaacgtgc tccagaccca aatctaacat agttctcctg 780
tcagcagaag aaaaaaaaga acagactatt gaaataaaag aagaagtggt tgggctaact 840
gaaacatctt cccaaccaaa gaatgaagaa gacattgaaa ttattccaat ccaagaagag 900
gaagaagaag aaacagagac gaactttcca gaacctcccc aagatcagga atcctcacca 960
atagaaaatg acagctctcc ttaagtgatt tcttctgttt tctgtttcct tttttaaaca 1020
ttagtgttca tagcttccaa gagacatgct gactttcatt tcttgaggta ctctgcacat 1080
acgcaccaca tctctatctg gcctttgcat ggagtgacca tagctccttc tctcttacat 1140
tgaatgtaga gaatgtagcc attgtagcag cttgtgttgt cacgcttctt cttttgagca 1200
actttcttac actgaagaaa ggcagaatga gtgcttcaga atgtgatttc ctactaacct 1260
gttccttgga taggcttttt agtatagtat ttttttttgt cattttctcc atcagcaacc 1320
agggagactg cacctgatgg aaaagatata tgactgcttc atgacattcc taaactatct 1380
tttttttatt ccacatctac gtttttggtg gagtcccttt tgcatcattg ttttaaggat 1440
gataaaaaaa aaataacaac tagggacaat acagaaccca ttccatttat ctttctacag 1500
ggctgacatt gtggcacatt cttagagtta ccacacccca tgagggaagc tctaaatagc 1560
caacacccat ctgttttttg taaaaacagc atagctt 1597
<210>18
<211>2907
<212>DNA
<213>人
<400>18
gccatctggg cccaggcccc atgccccgag gaggggtggt ctgaagccca ccagagcccc 60
ctgccagact gtctgcctcc cttctgactg tggccgcttg gcatggccag caacagcagc 120
tcctgcccga cacctggggg cgggcacctc aatgggtacc cggtgcctcc ctacgccttc 180
ttcttccccc ctatgctggg tggactctcc ccgccaggcg ctctgaccac tctccagcac 240
cagcttccag ttagtggata tagcacacca tccccagcca ccattgagac ccagagcagc 300
agttctgaag agatagtgcc cagccctccc tcgccacccc ctctaccccg catctacaag 360
ccttgctttg tctgtcagga caagtcctca ggctaccact atggggtcag cgcctgtgag 420
ggctgcaagg gcttcttccg ccgcagcatc cagaagaaca tggtgtacac gtgtcaccgg 480
gacaagaact gcatcatcaa caaggtgacc cggaaccgct gccagtactg ccgactgcag 540
aagtgctttg aagtgggcat gtccaaggag tctgtgagaa acgaccgaaa caagaagaag 600
aaggaggtgc ccaagcccga gtgctctgag agctacacgc tgacgccgga ggtgggggag 660
ctcattgaga aggtgcgcaa agcgcaccag gaaaccttcc ctgccctctg ccagctgggc 720
aaatacacta cgaacaacag ctcagaacaa cgtgtctctc tggacattga cctctgggac 780
aagttcagtg aactctccac caagtgcatc attaagactg tggagttcgc caagcagctg 840
cccggcttca ccaccctcac catcgccgac cagatcaccc tcctcaaggc tgcctgcctg 900
gacatcctga tcctgcggat ctgcacgcgg tacacgcccg agcaggacac catgaccttc 960
tcggacgggc tgaccctgaa ccggacccag atgcacaacg ctggcttcgg ccccctcacc 1020
gacctggtct ttgccttcgc caaccagctg ctgcccctgg agatggatga tgcggagacg 1080
gggctgctca gcgccatctg cctcatctgc ggagaccgcc aggacctgga gcagccggac 1140
cgggtggaca tgctgcagga gccgctgctg gaggcgctaa aggtctacgt gcggaagcgg 1200
aggcccagcc gcccccacat gttccccaag atgctaatga agattactga cctgcgaagc 1260
atcagcgcca agggggctga gcgggtgatc acgctgaaga tggagatccc gggctccatg 1320
ccgcctctca tccaggaaat gttggagaac tcagagggcc tggacactct gagcggacag 1380
ccggggggtg gggggcggga cgggggtggc ctggcccccc cgccaggcag ctgtagcccc 1440
agcctcagcc ccagctccaa cagaagcagc ccggccaccc actccccgtg accgcccacg 1500
ccacatggac acagccctcg ccctccgccc cggcttttct ctgcctttct accgaccatg 1560
tgaccccgca ccagccctgc ccccacctgc cctcccgggc agtactgggg accttccctg 1620
ggggacgggg agggaggagg cagcgactcc ttggacagag gcctgggccc tcagtggact 1680
gcctgctccc acagcctggg ctgacgtcag aggccgaggc caggaactga gtgaggcccc 1740
tggtcctggg tctcaggatg ggtcctgggg gcctcgtgtt catcaagaca cccctctgcc 1800
cagctcacca catcttcatc accagcaaac gccaggactt ggctccccca tcctcagaac 1860
tcacaagcca ttgctcccca gctggggaac ctcaacctcc cccctgcctc ggttggtgac 1920
agagggggtg ggacaggggc ggggggttcc ccctgtacat accctgccat accaacccca 1980
ggtattaatt ctcgctggtt ttgtttttat tttaattttt ttgttttgat ttttttaata 2040
agaattttca ttttaagcac atttatactg aaggaatttg tgctgtgtat tggggggagc 2100
tggatccaga gctggagggg gtgggtccgg gggagggagt ggctcggaag gggcccccac 2160
tctcctttca tgtccctgtg ccccccagtt ctcctcctca gccttttcct cctcagtttt 2220
ctctttaaaa ctgtgaagta ctaactttcc aaggcctgcc ttcccctccc tcccactgga 2280
gaagccgcca gcccctttct ccctctgcct gaccactggg tgtggacggt gtggggcagc 2340
cctgaaagga caggctcctg gccttggcac ttgcctgcac ccaccatgag gcatggagca 2400
gggcagagca agggccccgg gacagagttt tcccagacct ggctcctcgg cagagctgcc 2460
tcccgtcagg gcccacatca tctaggctcc ccagccccca ctgtgaaggg gctggccagg 2520
ggcccgagct gcccccaccc ccggcctcag ccaccagcac ccccataggg cccccagaca 2580
ccacacacat gcgcgtgcgc acacacacaa acacacacac actggacagt agatgggccg 2640
acacacactt ggcccgagtt cctccatttc cctggcctgc cccccacccc caacctgtcc 2700
cacccccgtg ccccctcctt accccgcagg acgggcctac aggggggtct cccctcaccc 2760
ctgcaccccc agctggggga gctggctctg ccccgacctc cttcaccagg ggttggggcc 2820
ccttcccctg gagcccgtgg gtgcacctgt tactgttggg ctttccactg agatctactg 2880
gataaagaat aaagttctat ttattct 2907
<210>19
<211>2907
<212>DNA
<213>人
<400>19
gccatctggg cccaggcccc atgccccgag gaggggtggt ctgaagccca ccagagcccc 60
ctgccagact gtctgcctcc cttctgactg tggccgcttg gcatggccag caacagcagc 120
tcctgcccga cacctggggg cgggcacctc aatgggtacc cggtgcctcc ctacgccttc 180
ttcttccccc ctatgctggg tggactctcc ccgccaggcg ctctgaccac tctccagcac 240
cagcttccag ttagtggata tagcacacca tccccagcca ccattgagac ccagagcagc 300
agttctgaag agatagtgcc cagccctccc tcgccacccc ctctaccccg catctacaag 360
ccttgctttg tctgtcagga caagtcctca ggctaccact atggggtcag cgcctgtgag 420
ggctgcaagg gcttcttccg ccgcagcatc cagaagaaca tggtgtacac gtgtcaccgg 480
gacaagaact gcatcatcaa caaggtgacc cggaaccgct gccagtactg ccgactgcag 540
aagtgctttg aagtgggcat gtccaaggag tctgtgagaa acgaccgaaa caagaagaag 600
aaggaggtgc ccaagcccga gtgctctgag agctacacgc tgacgccgga ggtgggggag 660
ctcattgaga aggtgcgcaa agcgcaccag gaaaccttcc ctgccctctg ccagctgggc 720
aaatacacta cgaacaacag ctcagaacaa cgtgtctctc tggacattga cctctgggac 780
aagttcagtg aactctccac caagtgcatc attaagactg tggagttcgc caagcagctg 840
cccggcttca ccaccctcac catcgccgac cagatcaccc tcctcaaggc tgcctgcctg 900
gacatcctga tcctgcggat ctgcacgcgg tacacgcccg agcaggacac catgaccttc 960
tcggacgggc tgaccctgaa ccggacccag atgcacaacg ctggcttcgg ccccctcacc 1020
gacctggtct ttgccttcgc caaccagctg ctgcccctgg agatggatga tgcggagacg 1080
gggctgctca gcgccatctg cctcatctgc ggagaccgcc aggacctgga gcagccggac 1140
cgggtggaca tgctgcagga gccgctgctg gaggcgctaa aggtctacgt gcggaagcgg 1200
aggcccagcc gcccccacat gttccccaag atgctaatga agattactga cctgcgaagc 1260
atcagcgcca agggggctga gcgggtgatc acgctgaaga tggagatccc gggctccatg 1320
ccgcctctca tccaggaaat gttggagaac tcagagggcc tggacactct gagcggacag 1380
ccggggggtg gggggcggga cgggggtggc ctggcccccc cgccaggcag ctgtagcccc 1440
agcctcagcc ccagctccaa cagaagcagc ccggccaccc actccccgtg accgcccacg 1500
ccacatggac acagccctcg ccctccgccc cggcttttct ctgcctttct accgaccatg 1560
tgaccccgca ccagccctgc ccccacctgc cctcccgggc agtactgggg accttccctg 1620
ggggacgggg agggaggagg cagcgactcc ttggacagag gcctgggccc tcagtggact 1680
gcctgctccc acagcctggg ctgacgtcag aggccgaggc caggaactga gtgaggcccc 1740
tggtcctggg tctcaggatg ggtcctgggg gcctcgtgtt catcaagaca cccctctgcc 1800
cagctcacca catcttcatc accagcaaac gccaggactt ggctccccca tcctcagaac 1860
tcacaagcca ttgctcccca gctggggaac ctcaacctcc cccctgcctc ggttggtgac 1920
agagggggtg ggacaggggc ggggggttcc ccctgtacat accctgccat accaacccca 1980
ggtattaatt ctcgctggtt ttgtttttat tttaattttt ttgttttgat ttttttaata 2040
agaattttca ttttaagcac atttatactg aaggaatttg tgctgtgtat tggggggagc 2100
tggatccaga gctggagggg gtgggtccgg gggagggagt ggctcggaag gggcccccac 2160
tctcctttca tgtccctgtg ccccccagtt ctcctcctca gccttttcct cctcagtttt 2220
ctctttaaaa ctgtgaagta ctaactttcc aaggcctgcc ttcccctccc tcccactgga 2280
gaagccgcca gcccctttct ccctctgcct gaccactggg tgtggacggt gtggggcagc 2340
cctgaaagga caggctcctg gccttggcac ttgcctgcac ccaccatgag gcatggagca 2400
gggcagagca agggccccgg gacagagttt tcccagacct ggctcctcgg cagagctgcc 2460
tcccgtcagg gcccacatca tctaggctcc ccagccccca ctgtgaaggg gctggccagg 2520
ggcccgagct gcccccaccc ccggcctcag ccaccagcac ccccataggg cccccagaca 2580
ccacacacat gcgcgtgcgc acacacacaa acacacacac actggacagt agatgggccg 2640
acacacactt ggcccgagtt cctccatttc cctggcctgc cccccacccc caacctgtcc 2700
cacccccgtg ccccctcctt accccgcagg acgggcctac aggggggtct cccctcaccc 2760
ctgcaccccc agctggggga gctggctctg ccccgacctc cttcaccagg ggttggggcc 2820
ccttcccctg gagcccgtgg gtgcacctgt tactgttggg ctttccactg agatctactg 2880
gataaagaat aaagttctat ttattct 2907
<210>20
<211>1347
<212>DNA
<213>人
<400>20
atggatccca aatatttcat cttaattttg ttttgtggac acctgaacaa tacatttttt 60
tcaaagacag agacaattac aacagagaag cagtcacagc ctaccttata cacatcatca 120
atgtcacagg tattggctaa ttctcaaaac acaacaggga atcctttggg tcaaccaaca 180
caattcagcg acactttttc tggacaatca atatcacctg ccaaagtcac tgctggacaa 240
ccaacaccag ctgtctatac ctcttctgaa aaaccagaag cacatacttc tgctggacaa 300
ccacttgcct acaacaccaa acaaccaaca ccaatagcca acacctcctc ccagcaagcc 360
gtgttcacct ctgccagaca actaccatct gcccgtactt ctaccacaca accaccaaag 420
tcatttgtct atacttttac tcaacaatca tcatctgtcc agatcccttc tagaaaacaa 480
ataactgttc ataatccatc cacacaacca acatcaactg tcaaaaattc acctaggagt 540
acaccaggat ttatcttaga tactaccagt aacaaacaaa ccccacaaaa aaacaattat 600
aattcaatag ctgccatact aattggtgta cttctgactt ctatgttggt agctataatc 660
atcattgtac tttggaaatg cttaaggaaa ccagttttaa atgatcaaaa ttgggcaggt 720
agatctccat ttgctgatgg agaaacccct gacatttgta tggataacat cagagaaaat 780
gaaatatcca caaaacgtac atcaatcatt tcacttacac cctggaaacc aagcaaaagc 840
acacttttag cagatgactt agaaattaag ttgtttgaat caagtgaaaa cattgaagac 900
tccaacaacc ccaaaacaga gaaaataaaa gatcaagtaa atggtacatc agaagatagt 960
gctgatggtt caacagttgg aactgctgtt tcttcttcag atgatgcaga tctgcctcca 1020
ccacctcccc ttctggattt ggaaggacag gaaagtaacc aatctgacaa acccacaatg 1080
acaattgtat ctcctcttcc aaatgattct actagtctcc ctccatctct ggactgtctc 1140
aatcaagact gtggagatca taaatctgag ataatacaat catttccacc gcttgactca 1200
cttaacttgc ccctgccacc agtagatttt atgaaaaacc aagaagattc caaccttgag 1260
atccagtgtc aggagttctc tattcctccc aactctgatc aagatcttaa tgaatccctg 1320
ccacctccac ctgcagaact gttataa 1347
<210>21
<211>2170
<212>DNA
<213>人
<400>21
ctgagggctc atccctctgc agagcgcggg gtcaccggga ggagacgcca tgacgcccgc 60
cctcacagcc ctgctctgcc ttgggctgag tctgggcccc aggacccgcg tgcaggcagg 120
gcccttcccc aaacccaccc tctgggctga gccaggctct gtgatcagct gggggagccc 180
cgtgaccatc tggtgtcagg ggagcctgga ggcccaggag taccgactgg ataaagaggg 240
aagcccagag cccttggaca gaaataaccc actggaaccc aagaacaagg ccagattctc 300
catcccatcc atgacagagc accatgcggg gagataccgc tgccactatt acagctctgc 360
aggctggtca gagcccagcg accccctgga gctggtgatg acaggattct acaacaaacc 420
caccctctca gccctgccca gccctgtggt ggcctcaggg gggaatatga ccctccgatg 480
tggctcacag aagggatatc accattttgt tctgatgaag gaaggagaac accagctccc 540
ccggaccctg gactcacagc agctccacag tggggggttc caggccctgt tccctgtggg 600
ccccgtgaac cccagccaca ggtggaggtt cacatgctat tactattata tgaacacccc 660
ccaggtgtgg tcccacccca gtgaccccct ggagattctg ccctcaggcg tgtctaggaa 720
gccctccctc ctgaccctgc agggccctgt cctggcccct gggcagagcc tgaccctcca 780
gtgtggctct gatgtcggct acgacagatt tgttctgtat aaggaggggg aacgtgactt 840
cctccagcgc cctggccagc agccccaggc tgggctctcc caggccaact tcaccctggg 900
ccctgtgagc ccctcccacg ggggccagta caggtgctat ggtgcacaca acctctcctc 960
cgagtggtcg gcccccagcg accccctgaa catcctgatg gcaggacaga tctatgacac 1020
cgtctccctg tcagcacagc cgggccccac agtggcctca ggagagaacg tgaccctgct 1080
gtgtcagtca tggtggcagt ttgacacttt ccttctgacc aaagaagggg cagcccatcc 1140
cccactgcgt ctgagatcaa tgtacggagc tcataagtac caggctgaat tccccatgag 1200
tcctgtgacc tcagcccacg cggggaccta caggtgctac ggctcataca gctccaaccc 1260
ccacctgctg tctttcccca gtgagcccct ggaactcatg gtctcaggac actctggagg 1320
ctccagcctc ccacccacag ggccgccctc cacacctggt ctgggaagat acctggaggt 1380
tttgattggg gtctcggtgg ccttcgtcct gctgctcttc ctcctcctct tcctcctcct 1440
ccgacgtcag cgtcacagca aacacaggac atctgaccag agaaagactg atttccagcg 1500
tcctgcaggg gctgcggaga cagagcccaa ggacaggggc ctgctgagga ggtccagccc 1560
agctgctgac gtccaggaag aaaacctcta tgctgccgtg aaggacacac agtctgagga 1620
cagggtggag ctggacagtc agagcccaca cgatgaagac ccccaggcag tgacgtatgc 1680
cccggtgaaa cactccagtc ctaggagaga aatggcctct cctccctcct cactgtctgg 1740
ggaattcctg gacacaaagg acagacaggt ggaagaggac aggcagatgg acactgaggc 1800
tgctgcatct gaagcctccc aggatgtgac ctacgcccag ctgcacagct tgacccttag 1860
acggaaggca actgagcctc ctccatccca ggaaggggaa cctccagctg agcccagcat 1920
ctacgccact ctggccatcc actagcccgg ggggtacgca gaccccacac tcagcagaag 1980
gagactcagg actgctgaag gcacgggagc tgcccccagt ggacaccagt gaaccccagt 2040
cagcctggac ccctaacaca gaccatgagg agacgctggg aacttgtggg actcacctga 2100
ctcaaagatg actaatatcg tcccattttg gaaataaagc aacagacttc tcaacaatca 2160
atgagttaat 2170
<210>22
<211>1453
<212>DNA
<213>人
<400>22
gggagtgcat ccgccccaac ccttttcccc ctcgtctcct gtgagaattc cccgtcggat 60
acgagcagcg tggccgttgg ctgcctcgca caggacttcc ttcccgactc catcactttc 120
tcctggaaat acaagaacaa ctctgacatc agcagcaccc ggggcttccc atcagtcctg 180
agagggggca agtacgcagc cacctcacag gtgctgctgc cttccaagga cgtcatgcag 240
ggcacagacg aacacgtggt gtgcaaagtc cagcacccca acggcaacaa agaaaagaac 300
gtgcctcttc cagtgattgc cgagctgcct cccaaagtga gcgtcttcgt cccaccccgc 360
gacggcttct tcggcaaccc ccgcaagtcc aagctcatct gccaggccac gggtttcagt 420
ccccggcaga ttcaggtgtc ctggctgcgc gaggggaagc aggtggggtc tggcgtcacc 480
acggaccagg tgcaggctga ggccaaagag tctgggccca cgacctacaa ggtgaccagc 540
acactgacca tcaaagagag cgactggctc agccagagca tgttcacctg ccgcgtggat 600
cacaggggcc tgaccttcca gcagaatgcg tcctccatgt gtgtccccga tcaagacaca 660
gccatccggg tcttcgccat ccccccatcc tttgccagca tcttcctcac caagtccacc 720
aagttgacct gcctggtcac agacctgacc acctatgaca gcgtgaccat ctcctggacc 780
cgccagaatg gcgaagctgt gaaaacccac accaacatct ccgagagcca ccccaatgcc 840
actttcagcg ccgtgggtga ggccagcatc tgcgaggatg actggaattc cggggagagg 900
ttcacgtgca ccgtgaccca cacagacctg ccctcgccac tgaagcagac catctcccgg 960
cccaaggggg tggccctgca caggcccgat gtctacttgc tgccaccagc ccgggagcag 1020
ctgaacctgc gggagtcggc caccatcacg tgcctggtga cgggcttctc tcccgcggac 1080
gtcttcgtgc agtggatgca gagggggcag cccttgtccc cggagaagta tgtgaccagc 1140
gccccaatgc ctgagcccca ggccccaggc cggtacttcg cccacagcat cctgaccgtg 1200
tccgaagagg aatggaacac gggggagacc tacacctgcg tggtggccca tgaggccctg 1260
cccaacaggg tcaccgagag gaccgtggac aagtccaccg gtaaacccac cctgtacaac 1320
gtgtccctgg tcatgtccga cacagctggc acctgctact gaccctgctg gcctgcccac 1380
aggctcgggg cggctggccg ctctgtgtgt gcatgcaaac taacccgtgt caacggggtg 1440
agatgttgca tct 1453
<210>23
<211>1192
<212>DNA
<213>人
<400>23
cagatccatc aggtccaagc tgtgttgact accactgctt ttcccttcgt ctcaattatg 60
tcttggaaga aggctttgcg gatccctgga ggccttcggg tagcaactgt gaccttgatg 120
ctggcgatgc tgagcacccc ggtggctgag ggcagagact ctcccgagga tttcgtgtac 180
cagtttaagg gcatgtgcta cttcaccaac gggacggagc gcgtgcgtct tgtgaccaga 240
tacatctata accgagagga gtacgcacgc ttcgacagcg acgtgggggt gtatcgggcg 300
gtgacgccgc tggggccgcc tgacgccgag tactggaaca gccagaagga agtcctggag 360
aggacccggg cggagttgga cacggtgtgc agacacaact accagttgga gctccgcacg 420
accttgcagc ggcgagtgga gcccacagtg accatctccc catccaggac agaggccctc 480
aaccaccaca acctgctggt ctgctcagtg acagatttct atccagccca gatcaaagtc 540
cggtggtttc ggaatgacca ggaggagaca actggcgttg tgtccacccc ccttattagg 600
aacggtgact ggaccttcca gatcctggtg atgctggaaa tgactcccca gcgtggagac 660
gtctacacct gccacgtgga gcaccccagc ctccagaacc ccatcatcgt ggagtggcgg 720
gctcagtctg aatctgccca gagcaagatg ctgagtggca ttggaggctt cgtgctgggg 780
ctgatcttcc tcgggctggg ccttattatc catcacagga gtcagaaagg gctcctgcac 840
tgactcctga gactatttta actgggattg gttatcactt ttctgtaacg cctgcttgtc 900
cctgcccaga attcccagct gcctgtgtca gcctgtcccc cgagatcaga gtcctaccgt 960
ggctgtcacg cagccaccag gtcatctcct ttcatcccca cctcaaggct gatggctgtg 1020
accctgcttc ctgcactgac ccagagcctc tgcctgtgca cggccagctg cgtctactga 1080
ggccccaagg ggtttctgtt tctattctct cctcagactg ctcaagagaa gcacatgaaa 1140
accattacct gactttagag cttttttaca taattaaaca tgatcctgag tt 1192
<210>24
<211>2048
<212>DNA
<213>人
<400>24
atgtgaaggc acaagctgct gttatataca acagagtgaa ctgagcatca gtcagaaaaa 60
gtctatgttt gcagaaatac agatccaaga caaagacagg atgggcactg ctggaaaagt 120
tattaaatgc aaagcagctg tgctttggga gcagaagcaa cccttctcca ttgaggaaat 180
agaagttgcc ccaccaaaga ctaaagaagt tcgcattaag attttggcca caggaatctg 240
tcgcacagat gaccatgtga taaaaggaac aatggtgtcc aagtttccag tgattgtggg 300
acatgaggca actgggattg tagagagcat tggagaagga gtgactacag tgaaaccagg 360
tgacaaagtc atccctctct ttctgccaca atgtagagaa tgcaatgctt gtcgcaaccc 420
agatggcaac ctttgcatta ggagcgatat tactggtcgt ggagtactgg ctgatggcac 480
caccagattt acatgcaagg gcaaaccagt acaccacttc atgaacacca gtacatttac 540
cgagtacaca gtggtggatg aatcttctgt tgctaagatt gatgatgcag ctcctcctga 600
gaaagtctgt ttaattggct gtgggttttc cactggatat ggcgctgctg ttaaaactgg 660
caaggtcaaa cctggttcca cttgcgtcgt ctttggcctg ggaggagttg gcctgtcagt 720
catcatgggc tgtaagtcag ctggtgcatc taggatcatt gggattgacc tcaacaaaga 780
caaatttgag aaggccatgg ctgtaggtgc cactgagtgt atcagtccca aggactctac 840
caaacccatc agtgaggtgc tgtcagaaat gacaggcaac aacgtgggat acacctttga 900
agttattggg catcttgaaa ccatgattga tgccctggca tcctgccaca tgaactatgg 960
gaccagcgtg gttgtaggag ttcctccatc agccaagatg ctcacctatg acccgatgtt 1020
gctcttcact ggacgcacat ggaagggatg tgtctttgga ggtttgaaaa gcagagatga 1080
tgtcccaaaa ctagtgactg agttcctggc aaagaaattt gacctggacc agttgataac 1140
tcatgtttta ccatttaaaa aaatcagtga aggatttgag ctgctcaatt caggacaaag 1200
cattcgaacg gtcctgacgt tttgagatcc aaagtggcag gaggtctgtg ttgtcatggt 1260
gaactggagt ttctcttgtg agagttccct catctgaaat catgtatctg tctcacaaat 1320
acaagcataa gtagaagatt tgttgaagac atagaaccct tataaagaat tattaacctt 1380
tataaacatt taaagtcttg tgagcacctg ggaattagta taataacaat gttaatattt 1440
ttgatttaca ttttgtaagg ctataattgt atcttttaag aaaacataca cttggatttc 1500
tatgttgaaa tggagatttt taagagtttt aaccagctgc tgcagatata taactcaaaa 1560
cagatatagc gtataaagat atagtaaatg catctcccag agtaatattc acttaacaca 1620
ttgaaactat tattttttag atttgaatat aaatgtattt tttaaacact tgttatgagt 1680
taacttggat tacattttga aatcagttca ttccatgatg catattactg gattagatta 1740
agaaagacag aaaagattaa gggacgggca catttttcaa cgattaagaa tcatcattac 1800
ataacttggt gaaactgaaa aagtatatca tatgggtaca caaggctatt tgccagcata 1860
tattaatatt ttagaaaata ttccttttgt aatactgaat ataaacatag agctagagtc 1920
atattatcat acttatcata atgttcaatt tgatacagta gaattgcaag tccctaagtc 1980
cctattcact gtgcttagta gtgactccat ttaataaaaa gtgtttttag tttttaacaa 2040
ctaaaccg 2048
<210>25
<211>2048
<212>DNA
<213>人
<400>25
atgtgaaggc acaagctgct gttatataca acagagtgaa ctgagcatca gtcagaaaaa 60
gtctatgttt gcagaaatac agatccaaga caaagacagg atgggcactg ctggaaaagt 120
tattaaatgc aaagcagctg tgctttggga gcagaagcaa cccttctcca ttgaggaaat 180
agaagttgcc ccaccaaaga ctaaagaagt tcgcattaag attttggcca caggaatctg 240
tcgcacagat gaccatgtga taaaaggaac aatggtgtcc aagtttccag tgattgtggg 300
acatgaggca actgggattg tagagagcat tggagaagga gtgactacag tgaaaccagg 360
tgacaaagtc atccctctct ttctgccaca atgtagagaa tgcaatgctt gtcgcaaccc 420
agatggcaac ctttgcatta ggagcgatat tactggtcgt ggagtactgg ctgatggcac 480
caccagattt acatgcaagg gcaaaccagt acaccacttc atgaacacca gtacatttac 540
cgagtacaca gtggtggatg aatcttctgt tgctaagatt gatgatgcag ctcctcctga 600
gaaagtctgt ttaattggct gtgggttttc cactggatat ggcgctgctg ttaaaactgg 660
caaggtcaaa cctggttcca cttgcgtcgt ctttggcctg ggaggagttg gcctgtcagt 720
catcatgggc tgtaagtcag ctggtgcatc taggatcatt gggattgacc tcaacaaaga 780
caaatttgag aaggccatgg ctgtaggtgc cactgagtgt atcagtccca aggactctac 840
caaacccatc agtgaggtgc tgtcagaaat gacaggcaac aacgtgggat acacctttga 900
agttattggg catcttgaaa ccatgattga tgccctggca tcctgccaca tgaactatgg 960
gaccagcgtg gttgtaggag ttcctccatc agccaagatg ctcacctatg acccgatgtt 1020
gctcttcact ggacgcacat ggaagggatg tgtctttgga ggtttgaaaa gcagagatga 1080
tgtcccaaaa ctagtgactg agttcctggc aaagaaattt gacctggacc agttgataac 1140
tcatgtttta ccatttaaaa aaatcagtga aggatttgag ctgctcaatt caggacaaag 1200
cattcgaacg gtcctgacgt tttgagatcc aaagtggcag gaggtctgtg ttgtcatggt 1260
gaactggagt ttctcttgtg agagttccct catctgaaat catgtatctg tctcacaaat 1320
acaagcataa gtagaagatt tgttgaagac atagaaccct tataaagaat tattaacctt 1380
tataaacatt taaagtcttg tgagcacctg ggaattagta taataacaat gttaatattt 1440
ttgatttaca ttttgtaagg ctataattgt atcttttaag aaaacataca cttggatttc 1500
tatgttgaaa tggagatttt taagagtttt aaccagctgc tgcagatata taactcaaaa 1560
cagatatagc gtataaagat atagtaaatg catctcccag agtaatattc acttaacaca 1620
ttgaaactat tattttttag atttgaatat aaatgtattt tttaaacact tgttatgagt 1680
taacttggat tacattttga aatcagttca ttccatgatg catattactg gattagatta 1740
agaaagacag aaaagattaa gggacgggca catttttcaa cgattaagaa tcatcattac 1800
ataacttggt gaaactgaaa aagtatatca tatgggtaca caaggctatt tgccagcata 1860
tattaatatt ttagaaaata ttccttttgt aatactgaat ataaacatag agctagagtc 1920
atattatcat acttatcata atgttcaatt tgatacagta gaattgcaag tccctaagtc 1980
cctattcact gtgcttagta gtgactccat ttaataaaaa gtgtttttag tttttaacaa 2040
ctaaaccg 2048
<210>26
<211>2816
<212>DNA
<213>人
<400>26
tcgttgatat caaagacagt tgaaggaaat gaattttgaa acttcacggt gtgccaccct 60
acagtactgc cctgaccctt acatccagcg tttcgtagaa acccagctca tttctcttgg 120
aaagaaagtt attaccgatc caccatgtcc cagagcacac agacaaatga attcctcagt 180
ccagaggttt tccagcatat ctgggatttt ctggaacagc ctatatgttc agttcagccc 240
attgacttga actttgtgga tgaaccatca gaagatggtg cgacaaacaa gattgagatt 300
agcatggact gtatccgcat gcaggactcg gacctgagtg accccatgtg gccacagtac 360
acgaacctgg ggctcctgaa cagcatggac cagcagattc agaacggctc ctcgtccacc 420
agtccctata acacagacca cgcgcagaac agcgtcacgg cgccctcgcc ctacgcacag 480
cccagctcca ccttcgatgc tctctctcca tcacccgcca tcccctccaa caccgactac 540
ccaggcccgc acagtttcga cgtgtccttc cagcagtcga gcaccgccaa gtcggccacc 600
tggacgtatt ccactgaact gaagaaactc tactgccaaa ttgcaaagac atgccccatc 660
cagatcaagg tgatgacccc acctcctcag ggagctgtta tccgcgccat gcctgtctac 720
aaaaaagctg agcacgtcac ggaggtggtg aagcggtgcc ccaaccatga gctgagccgt 780
gaattcaacg agggacagat tgcccctcct agtcatttga ttcgagtaga ggggaacagc 840
catgcccagt atgtagaaga tcccatcaca ggaagacaga gtgtgctggt accttatgag 900
ccaccccagg ttggcactga attcacgaca gtcttgtaca atttcatgtg taacagcagt 960
tgtgttggag ggatgaaccg ccgtccaatt ttaatcattg ttactctgga aaccagagat 1020
gggcaagtcc tgggccgacg ctgctttgag gcccggatct gtgcttgccc aggaagagac 1080
aggaaggcgg atgaagatag catcagaaag cagcaagttt cggacagtac aaagaacggt 1140
gatggtacga agcgcccgtt tcgtcagaac acacatggta tccagatgac atccatcaag 1200
aaacgaagat ccccagatga tgaactgtta tacttaccag tgaggggccg tgagacttat 1260
gaaatgctgt tgaagatcaa agagtccctg gaactcatgc agtaccttcc tcagcacaca 1320
attgaaacgt acaggcaaca gcaacagcag cagcaccagc acttacttca gaaacatctc 1380
ctttcagcct gcttcaggaa tgagcttgtg gagccccgga gagaaactcc aaaacaatct 1440
gacgtcttct ttagacattc caagccccca aaccgatcag tgtacccata gagccctatc 1500
tctatatttt aagtgtgtgt gttgtatttc catgtgtata tgtgagtgtg tgtgtgtgta 1560
tgtgtgtgcg tgtgtatcta gccctcataa acaggacttg aagacacttt ggctcagaga 1620
cccaactgct caaaggcaca aagccactag tgagagaatc ttttgaaggg actcaaacct 1680
ttacaagaaa ggatgttttc tgcagatttt gtatccttag accggccatt ggtgggtgag 1740
gaaccactgt gtttgtctgt gagctttctg ttgtttcctg ggagggaggg gtcaggtggg 1800
gaaaggggca ttaagatgtt tattggaacc cttttctgtc ttcttctgtt gtttttctaa 1860
aattcacagg gaagcttttg agcaggtctc aaacttaaga tgtcttttta agaaaaggag 1920
aaaaaagttg ttattgtctg tgcataagta agttgtaggt gactgagaga ctcagtcaga 1980
cccttttaat gctggtcatg taataatatt gcaagtagta agaaacgaag gtgtcaagtg 2040
tactgctggg cagcgaggtg atcattacca aaagtaatca actttgtggg tggagagttc 2100
tttgtgagaa cttgcattat ttgtgtcctc ccctcatgtg taggtagaac atttcttaat 2160
gctgtgtacc tgcctctgcc actgtatgtt ggcatctgtt atgctaaagt ttttcttgta 2220
catgaaaccc tggaagacct actacaaaaa aactgttgtt tggcccccat agcaggtgaa 2280
ctcattttgt gcttttaata gaaagacaaa tccaccccag taatattgcc cttacgtagt 2340
tgtttaccat tattcaaagc tcaaaataga atttgaagcc ctctcacaaa atctgtgatt 2400
aatttgctta attagagctt ctatccctca agcctaccta ccataaaacc agccatatta 2460
ctgatactgt tcagtgcatt tagccaggag acttacgttt tgagtaagtg agatccaagc 2520
agacgtgtta aaatcagcac tcctggactg gaaattaaag attgaaaggg tagactactt 2580
ttcttttttt tactcaaaag tttagagaat ctctgtttct ttccatttta aaaacatatt 2640
ttaagataat agcataaaga ctttaaaaat gttcctcccc tccatcttcc cacacccagt 2700
caccagcact gtattttctg tcaccaagac aatgatttct tgttattgag gctgttgctt 2760
ttgtggatgt gtgattttaa ttttcaataa acttttgcat cttggtttaa aagaaa 2816
<210>27
<211>2816
<212>DNA
<213>人
<400>27
tcgttgatat caaagacagt tgaaggaaat gaattttgaa acttcacggt gtgccaccct 60
acagtactgc cctgaccctt acatccagcg tttcgtagaa acccagctca tttctcttgg 120
aaagaaagtt attaccgatc caccatgtcc cagagcacac agacaaatga attcctcagt 180
ccagaggttt tccagcatat ctgggatttt ctggaacagc ctatatgttc agttcagccc 240
attgacttga actttgtgga tgaaccatca gaagatggtg cgacaaacaa gattgagatt 300
agcatggact gtatccgcat gcaggactcg gacctgagtg accccatgtg gccacagtac 360
acgaacctgg ggctcctgaa cagcatggac cagcagattc agaacggctc ctcgtccacc 420
agtccctata acacagacca cgcgcagaac agcgtcacgg cgccctcgcc ctacgcacag 480
cccagctcca ccttcgatgc tctctctcca tcacccgcca tcccctccaa caccgactac 540
ccaggcccgc acagtttcga cgtgtccttc cagcagtcga gcaccgccaa gtcggccacc 600
tggacgtatt ccactgaact gaagaaactc tactgccaaa ttgcaaagac atgccccatc 660
cagatcaagg tgatgacccc acctcctcag ggagctgtta tccgcgccat gcctgtctac 720
aaaaaagctg agcacgtcac ggaggtggtg aagcggtgcc ccaaccatga gctgagccgt 780
gaattcaacg agggacagat tgcccctcct agtcatttga ttcgagtaga ggggaacagc 840
catgcccagt atgtagaaga tcccatcaca ggaagacaga gtgtgctggt accttatgag 900
ccaccccagg ttggcactga attcacgaca gtcttgtaca atttcatgtg taacagcagt 960
tgtgttggag ggatgaaccg ccgtccaatt ttaatcattg ttactctgga aaccagagat 1020
gggcaagtcc tgggccgacg ctgctttgag gcccggatct gtgcttgccc aggaagagac 1080
aggaaggcgg atgaagatag catcagaaag cagcaagttt cggacagtac aaagaacggt 1140
gatggtacga agcgcccgtt tcgtcagaac acacatggta tccagatgac atccatcaag 1200
aaacgaagat ccccagatga tgaactgtta tacttaccag tgaggggccg tgagacttat 1260
gaaatgctgt tgaagatcaa agagtccctg gaactcatgc agtaccttcc tcagcacaca 1320
attgaaacgt acaggcaaca gcaacagcag cagcaccagc acttacttca gaaacatctc 1380
ctttcagcct gcttcaggaa tgagcttgtg gagccccgga gagaaactcc aaaacaatct 1440
gacgtcttct ttagacattc caagccccca aaccgatcag tgtacccata gagccctatc 1500
tctatatttt aagtgtgtgt gttgtatttc catgtgtata tgtgagtgtg tgtgtgtgta 1560
tgtgtgtgcg tgtgtatcta gccctcataa acaggacttg aagacacttt ggctcagaga 1620
cccaactgct caaaggcaca aagccactag tgagagaatc ttttgaaggg actcaaacct 1680
ttacaagaaa ggatgttttc tgcagatttt gtatccttag accggccatt ggtgggtgag 1740
gaaccactgt gtttgtctgt gagctttctg ttgtttcctg ggagggaggg gtcaggtggg 1800
gaaaggggca ttaagatgtt tattggaacc cttttctgtc ttcttctgtt gtttttctaa 1860
aattcacagg gaagcttttg agcaggtctc aaacttaaga tgtcttttta agaaaaggag 1920
aaaaaagttg ttattgtctg tgcataagta agttgtaggt gactgagaga ctcagtcaga 1980
cccttttaat gctggtcatg taataatatt gcaagtagta agaaacgaag gtgtcaagtg 2040
tactgctggg cagcgaggtg atcattacca aaagtaatca actttgtggg tggagagttc 2100
tttgtgagaa cttgcattat ttgtgtcctc ccctcatgtg taggtagaac atttcttaat 2160
gctgtgtacc tgcctctgcc actgtatgtt ggcatctgtt atgctaaagt ttttcttgta 2220
catgaaaccc tggaagacct actacaaaaa aactgttgtt tggcccccat agcaggtgaa 2280
ctcattttgt gcttttaata gaaagacaaa tccaccccag taatattgcc cttacgtagt 2340
tgtttaccat tattcaaagc tcaaaataga atttgaagcc ctctcacaaa atctgtgatt 2400
aatttgctta attagagctt ctatccctca agcctaccta ccataaaacc agccatatta 2460
ctgatactgt tcagtgcatt tagccaggag acttacgttt tgagtaagtg agatccaagc 2520
agacgtgtta aaatcagcac tcctggactg gaaattaaag attgaaaggg tagactactt 2580
ttcttttttt tactcaaaag tttagagaat ctctgtttct ttccatttta aaaacatatt 2640
ttaagataat agcataaaga ctttaaaaat gttcctcccc tccatcttcc cacacccagt 2700
caccagcact gtattttctg tcaccaagac aatgatttct tgttattgag gctgttgctt 2760
ttgtggatgt gtgattttaa ttttcaataa acttttgcat cttggtttaa aagaaa 2816
<210>28
<211>3803
<212>DNA
<213>人
<400>28
ccatggtagg agcgctcgcc tcgctgcggt gcccgctgag gccatgccgg ggccccggcg 60
ccccgctggc tcccgcctgc gcctgctcct gctcctgctg ctgccgccgc tgctgctgct 120
gctccggggc agccacgcgg gcaacctgac ggtagccgtg gtactgccgc tggccaatac 180
ctcgtacccc tggtcgtggg cgcgcgtggg acccgccgtg gagctggccc tggcccaggt 240
gaaggcgcgc cccgacttgc tgccgggctg gacggtccgc acggtgctgg gcagcagcga 300
aaacgcgctg ggcgtctgct ccgacaccgc agcgcccctg gccgcggtgg acctcaagtg 360
ggagcacaac cccgctgtgt tcctgggccc cggctgcgtg tacgccgccg ccccagtggg 420
gcgcttcacc gcgcactggc gggtcccgct gctgaccgcc ggcgccccgg cgctgggctt 480
cggtgtcaag gacgagtatg cgctgaccac ccgcgcgggg cccagctacg ccaagctggg 540
ggacttcgtg gcggcgctgc accgacggct gggctgggag cgccaagcgc tcatgctcta 600
cgcctaccgg ccgggtgacg aagagcactg cttcttcctc gtggaggggc tgttcatgcg 660
ggtccgcgac cgcctcaata ttacggtgga ccacctggag ttcgccgagg acgacctcag 720
ccactacacc aggctgctgc ggaccatgcc gcgcaaaggc cgagttatct acatctgcag 780
ctcccctgat gccttcagaa ccctcatgct cctggccctg gaagctggct tgtgtgggga 840
ggactacgtt ttcttccacc tggatatctt tgggcaaagc ctgcaaggtg gacagggccc 900
tgctccccgc aggccctggg agagagggga tgggcaggat gtcagtgccc gccaggcctt 960
tcaggctgcc aaaatcatta catataaaga cccagataat cccgagtact tggaattcct 1020
gaagcagtta aaacacctgg cctatgagca gttcaacttc accatggagg atggcctggt 1080
gaacaccatc ccagcatcct tccacgacgg gctcctgctc tatatccagg cagtgacgga 1140
gactctggca catgggggaa ctgttactga tggggagaac atcactcagc ggatgtggaa 1200
ccgaagcttt caaggtgtga caggatacct gaaaattgat agcagtggcg atcgggaaac 1260
agacttctcc ctctgggata tggatcccga gaatggtgcc ttcagggttg tactgaacta 1320
caatgggact tcccaagagc tggtggctgt gtcggggcgc aaactgaact ggcccctggg 1380
gtaccctcct cctgacatcc ccaaatgtgg ctttgacaac gaagacccag catgcaacca 1440
agatcacctt tccaccctgg aggtgctggc tttggtgggc agcctctcct tgctcggcat 1500
tctgattgtc tccttcttca tatacaggaa gatgcagctg gagaaggaac tggcctcgga 1560
gctgtggcgg gtgcgctggg aggacgttga gcccagtagc cttgagaggc acctgcggag 1620
tgcaggcagc cggctgaccc tgagcgggag aggctccaat tacggctccc tgctaaccac 1680
agagggccag ttccaagtct ttgccaagac agcatattat aagggcaacc tcgtggctgt 1740
gaaacgtgtg aaccgtaaac gcattgagct gacacgaaaa gtcctgtttg aactgaagca 1800
tatgcgggat gtgcagaatg aacacctgac caggtttgtg ggagcctgca ccgacccccc 1860
caatatctgc atcctcacag agtactgtcc ccgtgggagc ctgcaggaca ttctggagaa 1920
tgagagcatc accctggact ggatgttccg gtactcactc accaatgaca tcgtcaaggg 1980
catgctgttt ctacacaatg gggctatctg ttcccatggg aacctcaagt catccaactg 2040
cgtggtagat gggcgctttg tgctcaagat caccgactat gggctggaga gcttcaggga 2100
cctggaccca gagcaaggac acaccgttta tgccaaaaag ctgtggacgg cccctgagct 2160
cctgcgaatg gcttcacccc ctgtgcgggg ctcccaggct ggtgacgtat acagctttgg 2220
gatcatcctt caggagattg ccctgaggag tggggtcttc cacgtggaag gtttggacct 2280
gagccccaaa gagatcatcg agcgggtgac tcggggtgag cagcccccct tccggccctc 2340
cctggccctg cagagtcacc tggaggagtt ggggctgctc atgcagcggt gctgggctga 2400
ggacccacag gagaggccac cattccagca gatccgcctg acgttgcgca aatttaacag 2460
ggagaacagc agcaacatcc tggacaacct gctgtcccgc atggagcagt acgcgaacaa 2520
tctggaggaa ctggtggagg agcggaccca ggcatacctg gaggagaagc gcaaggctga 2580
ggccctgctc taccagatcc tgcctcactc agtggctgag cagctgaagc gtggggagac 2640
ggtgcaggcc gaagcctttg acagtgttac catctacttc agtgacattg tgggtttcac 2700
agcgctgtcg gcggagagca cacccatgca ggtggtgacc ctgctcaatg acctgtacac 2760
ttgctttgat gctgtcatag acaactttga tgtgtacaag gtggagacaa ttggcgatgc 2820
ctacatggtg gtgtcagggc tccctgtgcg gaacgggcgg ctacacgcct gcgaggtagc 2880
ccgcatggcc ctggcactgc tggatgctgt gcgctccttc cgaatccgcc accggcccca 2940
ggagcagctg cgcttgcgca ttggcatcca cacaggacct gtgtgtgctg gagtggtggg 3000
actgaagatg ccccgttact gtctctttgg ggatacagtc aacacagcct caagaatgga 3060
gtctaatggg gaagccctga agatccactt gtcttctgag accaaggctg tcctggagga 3120
gtttggtggt ttcgagctgg agcttcgagg ggatgtagaa atgaagggca aaggcaaggt 3180
tcggacctac tggctccttg gggagagggg gagtagcacc cgaggctgac ctgcctcctc 3240
tcctatccct ccacacctcc cctaccctgt gccagaagca acagaggtgc caggcctcag 3300
cctcacccac agcagcccca tcgccaaagg atggaagtaa tttgaatagc tcaggtgtgc 3360
tgaccccagt gaagacacca gataggacct ctgagagggg actggcatgg ggggatctca 3420
gagcttacag gctgagccaa gcccacggcc atgcacaggg acactcacac aggcacacgc 3480
acctgctctc cacctggact caggccgggc tgggctgtgg atccttgatc ccctcccctc 3540
cccatgctct cctccctcag ccttgctacc ctgtgactta ctgggaggag agtcacctga 3600
aggggaacat gaaaagagac taggtgaaga gagggcaggg gagcccacat ctggggctgg 3660
cccacaatac ctgctccccc gaccccctcc acccagcagt agacacagtg cacaggggag 3720
aagaggggtg gcgcagaagg gttgggggcc tgtatgcctt gcttctacca tgagcagaga 3780
caattaaaat ctttattcca gtg 3803
<210>29
<211>3802
<212>DNA
<213>人
<400>29
ccatggtagg agcgctcgcc tcgctgcggt gcccgctgag gccatgccgg ggccccggcg 60
ccccgctggc tcccgcctgc gcctgctcct gctcctgctg ctgccgccgc tgctgctgct 120
gctccggggc agccacgcgg gcaacctgac ggtagccgtg gtactgccgc tggccaatac 180
ctcgtacccc tggtcgtggg cgcgcgtggg acccgccgtg gagctggccc tggcccaggt 240
gaaggcgcgc cccgacttgc tgccgggctg gacggtccgc acggtgctgg gcagcagcga 300
aaacgcgctg ggcgtctgct ccgacaccgc agcgcccctg gccgcggtgg acctcaagtg 360
ggagcacaac cccgctgtgt tcctgggccc cggctgcgtg tacgccgccg ccccagtggg 420
gcgcttcacc gcgcactggc gggtcccgct gctgaccgcc ggcgccccgg cgctgggctt 480
cggtgtcaag gacgagtatg cgctgaccac ccgcgcgggg cccagctacg ccaagctggg 540
ggacttcgtg gcggcgctgc accgacggct gggctgggag cgccaagcgc tcatgctcta 600
cgcctaccgg ccgggtgacg aagagcactg cttcttcctc gtggaggggc tgttcatgcg 660
ggtccgcgac cgcctcaata ttacggtgga ccacctggag ttcgccgagg acgacctcag 720
ccactacacc aggctgctgc ggaccatgcc gcgcaaaggc cgagttatct acatctgcag 780
ctcccctgat gccttcagaa ccctcatgct cctggccctg gaagctggct tgtgtgggga 840
ggactacgtt ttcttccacc tggatatctt tgggcaaagc ctgcaaggtg gacagggccc 900
tgctccccgc aggccctggg agagagggga tgggcaggat gtcagtgccc gccaggcctt 960
tcaggctgcc aaaatcatta catataaaga cccagataat cccgagtact tggaattcct 1020
gaagcagtta aaacacctgg cctatgagca gttcaacttc accatggagg atggcctggt 1080
gaacaccatc ccagcatcct tccacgacgg gctcctgctc tatatccagg cagtgacgga 1140
gactctggca catgggggaa ctgttactga tggggagaac atcactcagc ggatgtggaa 1200
ccgaagcttt caaggtgtga caggatacct gaaaattgat agcagtggcg atcgggaaac 1260
agacttctcc ctctgggata tggatcccga gaatggtgcc ttcagggttg tactgaacta 1320
caatgggact tcccaagagc tggtggctgt gtcggggcgc aaactgaact ggcccctggg 1380
gtaccctcct cctgacatcc ccaaatgtgg ctttgacaac gaagacccag catgcaacca 1440
agatcacctt tccaccctgg aggtgctggc tttggtgggc agcctctcct tgctcggcat 1500
tctgattgtc tccttcttca tatacaggaa gatgcagctg gagaaggaac tggcctcgga 1560
gctgtggcgg gtgcgctggg aggacgttga gcccagtagc cttgagaggc acctgcggag 1620
tgcaggcagc cggctgaccc tgagcgggag aggctccaat tacggctccc tgctaaccac 1680
agagggccag ttccaagtct ttgccaagac agcatattat aagggcaacc tcgtggctgt 1740
gaaacgtgtg aaccgtaaac gcattgagct gacacgaaaa gtcctgtttg aactgaagca 1800
tatgcgggat gtgcagaatg aacacctgac caggtttgtg ggagcctgca ccgacccccc 1860
caatatctgc atcctcacag agtactgtcc ccgtgggagc ctgcaggaca ttctggagaa 1920
tgagagcatc accctggact ggatgttccg gtactcactc accaatgaca tcgtcaaggg 1980
catgctgttt ctacacaatg gggctatctg ttcccatggg aacctcaagt catccaactg 2040
cgtggtagat gggcgctttg tgctcaagat caccgactat gggctggaga gcttcaggga 2100
cctggaccca gagcaaggac acaccgttta tgccaaaaag ctgtggacgg cccctgagct 2160
cctgcgaatg gcttcacccc ctgtgcgggg ctcccaggct ggtgacgtat acagctttgg 2220
gatcatcctt caggagattg ccctgaggag tggggtcttc cacgtggaag gtttggacct 2280
gagccccaaa gagatcatcg agcgggtgac tcggggtgag cagcccccct tccggccctc 2340
cctggccctg cagagtcacc tggaggagtt ggggctgctc atgcagcggt gctgggctga 2400
ggacccacag gagaggccac cattccagca gatccgcctg acgttgcgca aatttaacag 2460
ggagaacagc agcaacatcc tggacaacct gctgtcccgc atggagcagt acgcgaacaa 2520
tctggaggaa ctggtggagg agcggaccca ggcatacctg gaggagaagc gcaaggctga 2580
ggccctgctc taccagatcc tgcctcactc agtggctgag cagctgaagc gtggggagac 2640
ggtgcaggcc gaagcctttg acagtgttac catctacttc agtgacattg tgggtttcac 2700
agcgctgtcg gcggagagca cacccatcag gtggtgaccc tgctcaatga cctgtacact 2760
tgctttgatg ctgtcataga caactttgat gtgtacaagg tggagacaat tggcgatgcc 2820
tacatggtgg tgtcagggct ccctgtgcgg aacgggcggc tacacgcctg cgaggtagcc 2880
cgcatggccc tggcactgct ggatgctgtg cgctccttcc gaatccgcca ccggccccag 2940
gagcagctgc gcttgcgcat tggcatccac acaggacctg tgtgtgctgg agtggtggga 3000
ctgaagatgc cccgttactg tctctttggg gatacagtca acacagcctc aagaatggag 3060
tctaatgggg aagccctgaa gatccacttg tcttctgaga ccaaggctgt cctggaggag 3120
tttggtggtt tcgagctgga gcttcgaggg gatgtagaaa tgaagggcaa aggcaaggtt 3180
cggacctact ggctccttgg ggagaggggg agtagcaccc gaggctgacc tgcctcctct 3240
cctatccctc cacacctccc ctaccctgtg ccagaagcaa cagaggtgcc aggcctcagc 3300
ctcacccaca gcagccccat cgccaaagga tggaagtaat ttgaatagct caggtgtgct 3360
gaccccagtg aagacaccag ataggacctc tgagagggga ctggcatggg gggatctcag 3420
agcttacagg ctgagccaag cccacggcca tgcacaggga cactcacaca ggcacacgca 3480
cctgctctcc acctggactc aggccgggct gggctgtgga tccttgatcc cctcccctcc 3540
ccatgctctc ctccctcagc cttgctaccc tgtgacttac tgggaggaga gtcacctgaa 3600
ggggaacatg aaaagagact aggtgaagag agggcagggg agcccacatc tggggctggc 3660
ccacaatacc tgctcccccg accccctcca cccagcagta gacacagtgc acaggggaga 3720
agaggggtgg cgcagaaggg ttgggggcct gtatgccttg cttctaccat gagcagagac 3780
aattaaaatc tttattccag tg 3802
<210>30
<211>2970
<212>DNA
<213>人
<400>30
ggggtaagga gttcaaggca gcgcccacac ccgggggctc tccgcaaccc gaccgcctgt 60
ccgctccccc acttcccgcc ctccctccca cctactcatt cacccaccca cccacccaga 120
gccgggacgg cagcccaggc gcccgggccc cgccgtctcc tcgccgcgat cctggacttc 180
ctcttgctgc aggacccggc ttccacgtgt gtcccggagc cggcgtctca gcacacgctc 240
cgctccgggc ctgggtgcct acagcagcca gagcagcagg gagtccggga cccgggcggc 300
atctgggcca agttaggcgc cgccgaggcc agcgctgaac gtctccaggg ccggaggagc 360
cgcggggcgt ccgggtctga gcctcagcaa atgggctccg acgtgcggga cctgaacgcg 420
ctgctgcccg ccgtcccctc cctgggtggc ggcggcggct gtgccctgcc tgtgagcggc 480
gcggcgcagt gggcgccggt gctggacttt gcgcccccgg gcgcttcggc ttacgggtcg 540
ttgggcggcc ccgcgccgcc accggctccg ccgccacccc cgccgccgcc gcctcactcc 600
ttcatcaaac aggagccgag ctggggcggc gcggagccgc acgaggagca gtgcctgagc 660
gccttcactg tccacttttc cggccagttc actggcacag ccggagcctg tcgctacggg 720
cccttcggtc ctcctccgcc cagccaggcg tcatccggcc aggccaggat gtttcctaac 780
gcgccctacc tgcccagctg cctcgagagc cagcccgcta ttcgcaatca gggttacagc 840
acggtcacct tcgacgggac gcccagctac ggtcacacgc cctcgcacca tgcggcgcag 900
ttccccaacc actcattcaa gcatgaggat cccatgggcc agcagggctc gctgggtgag 960
cagcagtact cggtgccgcc cccggtctat ggctgccaca cccccaccga cagctgcacc 1020
ggcagccagg ctttgctgct gaggacgccc tacagcagtg acaatttata ccaaatgaca 1080
tcccagcttg aatgcatgac ctggaatcag atgaacttag gagccacctt aaagggccac 1140
agcacagggt acgagagcga taaccacaca acgcccatcc tctgcggagc ccaatacaga 1200
atacacacgc acggtgtctt cagaggcatt caggatgtgc gacgtgtgcc tggagtagcc 1260
ccgactcttg tacggtcggc atctgagacc agtgagaaac gccccttcat gtgtgcttac 1320
ccaggctgca ataagagata ttttaagctg tcccacttac agatgcacag caggaagcac 1380
actggtgaga aaccatacca gtgtgacttc aaggactgtg aacgaaggtt ttctcgttca 1440
gaccagctca aaagacacca aaggagacat acaggtgtga aaccattcca gtgtaaagct 1500
tgtcagcgaa agttctcccg gtccgaccac ctgaagaccc acaccaggac tcatacaggt 1560
gaaaagccct tcagctgtcg gtggccaagt tgtcagaaaa agtttgcccg gtcagatgaa 1620
ttagtccgcc atcacaacat gcatcagaga aacatgacca aactccagct ggcgctttga 1680
ggggtctccc tcggggaccg ttcagtgtcc caggcagcac agtgtgtgaa ctgctttcaa 1740
gtctgactct ccactcctcc tcactaaaaa ggaaacttca gttgatcttc ttcatccaac 1800
ttccaagaca agataccggt gcttctggaa actaccaggt gtgcctggaa gagttggtct 1860
ctgccctgcc tacttttagt tgactcacag gccctggaga agcagctaac aatgtctggt 1920
tagttaaaag cccattgcca tttggtctgg attttctact gtaagaagag ccatagctga 1980
tcatgtcccc ctgacccttc ccttcttttt ttatgctcgt tttcgctggg gatggaatta 2040
ttgtaccatt ttctatcatg gaatatttat aggccagggc atgtgtatgt gtctgctaat 2100
gtaaactttg tcatggtttc catttactaa cagcaacagc aagaaataaa tcagagagca 2160
aggcatcggg ggtgaatctt gtctaacatt cccgaggtca gccaggctgc taacctggaa 2220
agcaggatgt agttctgcca ggcaactttt aaagctcatg catttcaagc agctgaagaa 2280
agaatcagaa ctaaccagta cctctgtata gaaatctaaa agaattttac cattcagtta 2340
attcaatgtg aacactggca cactgctctt aagaaactat gaagatctga gatttttttg 2400
tgtatgtttt tgactctttt gagtggtaat catatgtgtc tttatagatg tacatacctc 2460
cttgcacaaa tggaggggaa ttcattttca tcactgggag tgtccttagt gtataaaaac 2520
catgctggta tatggcttca agttgtaaaa atgaaagtga ctttaaaaga aaatagggga 2580
tggtccagga tctccactga taagactgtt tttaagtaac ttaaggacct ttgggtctac 2640
aagtatatgt gaaaaaaatg agacttactg ggtgaggaaa tccattgttt aaagatggtc 2700
gtgtgtgtgt gtgtgtgtgt gtgtgtgttg tgttgtgttt tgttttttaa gggagggaat 2760
ttattattta ccgttgcttg aaattactgt gtaaatatat gtctgataat gatttgctct 2820
ttgacaacta aaattaggac tgtataagta ctagatgcat cactgggtgt tgatcttaca 2880
agatattgat gataacactt aaaattgtaa cctgcatttt tcactttgct ctcaattaaa 2940
gtctattcaa aaggaaaaaa aaaaaaaaaa 2970
<210>31
<211>2422
<212>DNA
<213>人
<400>31
gtcagcctcc cttccaccgc catattgggc cactaaaaaa agggggctcg tcttttcggg 60
gtgtttttct ccccctcccc tgtccccgct tgctcacggc tctgcgactc cgacgccggc 120
aaggtttgga gagcggctgg gttcgcggga cccgcgggct tgcacccgcc cagactcgga 180
cgggctttgc caccctctcc gcttgcctgg tcccctctcc tctccgccct cccgctcgcc 240
agtccatttg atcagcggag actcggcggc cgggccgggg cttccccgca gcccctgcgc 300
gctcctagag ctcgggccgt ggctcgtcgg ggtctgtgtc ttttggctcc gagggcagtc 360
gctgggcttc cgagaggggt tcgggccgcg taggggcgct ttgttttgtt cggttttgtt 420
tttttgagag tgcgagagag gcggtcgtgc agacccggga gaaagatgtc aaacgtgcga 480
gtgtctaacg ggagccctag cctggagcgg atggacgcca ggcaggcgga gcaccccaag 540
ccctcggcct gcaggaacct cttcggcccg gtggaccacg aagagttaac ccgggacttg 600
gagaagcact gcagagacat ggaagaggcg agccagcgca agtggaattt cgattttcag 660
aatcacaaac ccctagaggg caagtacgag tggcaagagg tggagaaggg cagcttgccc 720
gagttctact acagaccccc gcggcccccc aaaggtgcct gcaaggtgcc ggcgcaggag 780
agccaggatg tcagcgggag ccgcccggcg gcgcctttaa ttggggctcc ggctaactct 840
gaggacacgc atttggtgga cccaaagact gatccgtcgg acagccagac ggggttagcg 900
gagcaatgcg caggaataag gaagcgacct gcaaccgacg attcttctac tcaaaacaaa 960
agagccaaca gaacagaaga aaatgtttca gacggttccc caaatgccgg ttctgtggag 1020
cagacgccca agaagcctgg cctcagaaga cgtcaaacgt aaacagctcg aattaagaat 1080
atgtttcctt gtttatcaga tacatcactg cttgatgaag caaggaagat atacatgaaa 1140
attttaaaaa tacatatcgc tgacttcatg gaatggacat cctgtataag cactgaaaaa 1200
caacaacaca ataacactaa aattttaggc actcttaaat gatctgcctc taaaagcgtt 1260
ggatgtagca ttatgcaatt aggtttttcc ttatttgctt cattgtacta cctgtgtata 1320
tagtttttac cttttatgta gcacataaac tttggggaag ggagggcagg gtggggctga 1380
ggaactgacg tggagcgggg tatgaagagc ttgctttgat ttacagcaag tagataaata 1440
tttgacttgc atgaagagaa gcaattttgg ggaagggttt gaattgtttt ctttaaagat 1500
gtaatgtccc tttcagagac agctgatact tcatttaaaa aaatcacaaa aatttgaaca 1560
ctggctaaag ataattgcta tttattttta caagaagttt attctcattt gggagatctg 1620
gtgatctccc aagctatcta aagtttgtta gatagctgca tgtggctttt ttaaaaaagc 1680
aacagaaacc tatcctcact gccctcccca gtctctctta aagttggaat ttaccagtta 1740
attactcagc agaatggtga tcactccagg tagtttgggg caaaaatccg aggtgcttgg 1800
gagttttgaa tgttaagaat tgaccatctg cttttattaa atttgttgac aaaattttct 1860
cattttcttt tcacttcggg ctgtgtaaac acagtcaaaa taattctaaa tccctcgata 1920
tttttaaaga tctgtaagta acttcacatt aaaaaatgaa atatttttta atttaaagct 1980
tactctgtcc atttatccac aggaaagtgt tatttttaaa ggaaggttca tgtagagaaa 2040
agcacacttg taggataagt gaaatggata ctacatcttt aaacagtatt tcattgcctg 2100
tgtatggaaa aaccatttga agtgtacctg tgtacataac tctgtaaaaa cactgaaaaa 2160
ttatactaac ttatttatgt taaaagattt tttttaatct agacaatata caagccaaag 2220
tggcatgttt tgtgcatttg taaatgctgt gttgggtaga ataggttttc ccctcttttg 2280
ttaaataata tggctatgct taaaaggttg catactgagc caagtataat tttttgtaat 2340
gtgtgaaaaa gatgccaatt attgttacac attaagtaat caataaagaa aacttccata 2400
gctaaaaaaa aaaaaaaaaa aa 2422
<210>32
<211>1181
<212>DNA
<213>人
<400>32
ggcacgaggc ccgggccccc caaagtcccg gccgggccga gggtcggcgg ccgccggcgg 60
gccgggcccg cgcacagcgc ccgcatgtac aacatgatgg agacggagct gaagccgccg 120
ggcccgcagc aaacttcggg gggcggcggc ggcaactcca ccgcggcggc ggccggcggc 180
aaccagaaaa acagcccgga ccgcgtcaag cggcccatga atgccttcat ggtgtggtcc 240
cgcgggcagc ggcgcaagat ggcccaggag aaccccaaga tgcacaactc ggagatcagc 300
aagcgcctgg gcgccgagtg gaaacttttg tcggagacgg agaagcggcc gttcatcgac 360
gaggctaagc ggctgcgagc gctgcacatg aaggagcacc cggattataa ataccggccc 420
cggcggaaaa ccaagacgct catgaagaag gataagtaca cgctgcccgg cgggctgctg 480
gcccccggcg gcaatagcat ggcgagcggg gtcggggtgg gcgccggcct gggcgcgggc 540
gtgaaccagc gcatggacag ttacgcgcac atgaacggct ggagcaacgg cagctacagc 600
atgatgcagg accagctggg ctacccgcag cacccgggcc tcaatgcgca cggcgcagcg 660
cagatgcagc ccatgcaccg ctacgacgtg agcgccctgc agtacaactc catgaccagc 720
tcgcagacct acatgaacgg ctcgcccacc tacagcatgt cctactcgca gcagggcacc 780
cctggcatgg ctcttggctc catgggttcg gtggtcaagt ccgaggccag ctccagcccc 840
cctgtggtta cctcttcctc ccactccagg gcgccctgcc aggccgggga cctccgggac 900
atgatcagca tgtatctccc cggcgccgag gtgccggaac ccgccgcccc cagcagactt 960
cacatgtccc agcactacca gagcggcccg gtgcccggca cggccattaa cggcacactg 1020
cccctctcac acatgtgagg gccggacagc gaactggagg ggggagaaat tttcaaagaa 1080
aaacgaggga aatgggaggg gtgcaaaaga ggagagtaag aaacagcatg gagaaaaccc 1140
ggtacgctca aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a 1181
<210>33
<211>1305
<212>DNA
<213>人
<400>33
ggggccccgc gccggcccgc gccctgccca gtgcggcctc cttccacccg ccgctgcctg 60
gcccgcgccg tccggccgag ctgcccggcg ggctggtccc cgcgcccgag ccgcccggcc 120
gggaccccga acaaggccga gatgacttcc aaggaggacg gcaaggcggc gccgggggag 180
gagcggcgcc gcagcccgct ggaccacctg cctccgcctg ccaactccaa caagccagac 240
gccgttcagc atcgaggaca tcctcaacaa gccgtctgtg cggagaagtt actcgctgcg 300
tggggcggcg cacctgctgg ccgccgcgga caagcacgcg cagggcggct tgccctggcg 360
ggccgcgcgc tgctctcgaa gacctcgccg ctgtgcgcgc tggaggagct cgccagcaag 420
acgtttaagg ggctggaggt cagcgttctg caggcagccg aaggccgcga cggtatgacc 480
atctttgggc agcggcagac ccctaagaag cggcgaaagt cgcgcacggc cttcaccaac 540
caccagatct atgaattgga aaagcgcttt ctataccaga agtacctgtc ccccgccgat 600
cgcgaccaaa tcgcgcagca gctgggcctc accaacgcgc aagtcatcac ctggttccag 660
aatcggcgcg ctaagctcaa gcgggaactg gaggagatga aggccgacgt ggagtccccc 720
aagaaactgg gccccagcgg gcagatggac atcgtggcgc tggccgaact cgagcagaac 780
tcggaggcca cagccggcgg tggcggcggc tgcggcaggg ccaagtcgag gcccggctct 840
ccggtcctcc ccccaggcgc cccgaaggcc cccgggcgct gcgccctgca gctctcgcct 900
gcctctccgc tcacggacca gccggccagc agccaggact gctcggagga cgaggaagac 960
gaagagatcg acgtggacga ttgagcggcg ccccgggtct tccgccgccc tgggctccta 1020
gcgctcgaaa gcccaacgcc tcccggaccg gaccgccgag gggagctggg acctcctctg 1080
ccactcccgc ctcctcccct gtccccggac tcggctcctg gcagccgcct cttccctctc 1140
gaagcaataa acccaggctg gccggccggg ccggccgcca ccagcggcct ccgccgcccc 1200
ggaagccctc gccgagcaat tctgtatggc ttctatataa atatttaaac ctatatagcg 1260
ggttctcccc aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa 1305
<210>34
<211>1926
<212>DNA
<213>人
<400>34
gctggagcat cccgctctgg tgccgctgca gccggcagag atggttgagc tcatgttccc 60
gctgttgctc ctccttctgc ccttccttct gtatatggct gcgccccaaa tcaggaaaat 120
gctgtccagt ggggtgtgta catcaactgt tcagcttcct gggaaagtag ttgtggtcac 180
aggagctaat acaggtatcg ggaaggagac agccaaagag ctggctcaga gaggagctcg 240
agtatattta gcttgccggg atgtggaaaa gggggaattg gtggccaaag agatccagac 300
cacgacaggg aaccagcagg tgttggtgcg gaaactggac ctgtctgata ctaagtctat 360
tcgagctttt gctaagggct tcttagctga ggaaaagcac ctccacgttt tgatcaacaa 420
tgcaggagtg atgatgtgtc cgtactcgaa gacagcagat ggctttgaga tgcacatagg 480
agtcaaccac ttgggtcact tcctcctaac ccatctgctg ctagagaaac taaaggaatc 540
agccccatca aggatagtaa atgtgtcttc cctcgcacat cacctgggaa ggatccactt 600
ccataacctg cagggcgaga aattctacaa tgcaggcctg gcctactgtc acagcaagct 660
agccaacatc ctcttcaccc aggaactggc ccggagacta aaaggctctg gcgttacgac 720
gtattctgta caccctggca cagtccaatc tgaactggtt cggcactcat ctttcatgag 780
atggatgtgg tggcttttct cctttttcat caagactcct cagcagggag cccagaccag 840
cctgcactgt gccttaacag aaggtcttga gattctaagt gggaatcatt tcagtgactg 900
tcatgtggca tgggtctctg cccaagctcg taatgagact atagcaaggc ggctgtggga 960
cgtcagttgt gacctgctgg gcctcccaat agactaacag gcagtgcagt tggacccaag 1020
agaagactgc agcagactac acagtacttc ttgtcaaaat gattctcctt caaggttttc 1080
aaaaccttta gcacaaagag agcaaaacct tccagccttg cctgcttggt gtccagttaa 1140
aactcagtgt actgccagat tcgtctaaat gtctgtcatg tccagattta ctttgcttct 1200
gttactgcca gagttactag agatatcata ataggataag aagaccctca tatgacctgc 1260
acagctcatt ttccttctga aagaaactac tacctaggag aatctaagct atagcaggga 1320
tgatttatgc aaatttgaac tagcttcttt gttcacaatt cagttcctcc caaccaacca 1380
gtcttcactt caagagggcc acactgcaac ctcagcttaa catgaataac aaagactggc 1440
tcaggagcag ggcttgccca ggcatggtgg atcaccggag tcagtagttc aagaccagcc 1500
tggccaacat ggtgaaaccc cacctctact aaaaattgtg tatatctttg tgtgtcttcc 1560
tgtttatgtg tgccaaggga gtattttcac aaagttcaaa acagccacaa taatcagaga 1620
tggagcaaac cagtgccatc cagtctttat gcaaatgaaa tgctgcaaag ggaagcagat 1680
tctgtatatg ttggtaacta cccaccaaga gcacatgggt agcagggaag aagtaaaaaa 1740
agagaaggag aatactggaa gataatgcac aaaatgaagg gactagttaa ggattaacta 1800
gccctttaag gattaactag ttaaggatta atagcaaaag acattaaata tgctaacata 1860
gctatggagg aattgagggc aagcacccag gactgatgag gtcttaacaa aaaccagtgt 1920
ggcaaa 1926
<210>35
<211>1195
<212>DNA
<213>人
<400>35
ccgagactca cggtcaagct aaggcgaaga gtgggtggct gaagccatac tattttatag 60
aattaatgga aagcagaaaa gacatcacaa accaagaaga actttggaaa atgaagccta 120
ggagaaattt agaagaagac gattatttgc ataaggacac gggagagacc agcatgctaa 180
aaagacctgt gcttttgcat ttgcaccaaa cagcccatgc tgatgaattt gactgccctt 240
cagaacttca gcacacacag gaactctttc cacagtggca cttgccaatt aaaatagctg 300
ctattatagc atctctgact tttctttaca ctcttctgag ggaagtaatt caccctttag 360
caacttccca tcaacaatat ttttataaaa ttccaatcct ggtcatcaac aaagtcttgc 420
caatggtttc catcactctc ttggcattgg tttacctgcc aggtgtgata gcagcaattg 480
tccaacttca taatggaacc aagtataaga agtttccaca ttggttggat aagtggatgt 540
taacaagaaa gcagtttggg cttctcagtt tcttttttgc tgtactgcat gcaatttata 600
gtctgtctta cccaatgagg cgatcctaca gatacaagtt gctaaactgg gcatatcaac 660
aggtccaaca aaataaagaa gatgcctgga ttgagcatga tgtttggaga atggagattt 720
atgtgtctct gggaattgtg ggattggcaa tactggctct gttggctgtg acatctattc 780
catctgtgag tgactctttg acatggagag aatttcacta tattcagagc aagctaggaa 840
ttgtttccct tctactgggc acaatacacg cattgatttt tgcctggaat aagtggatag 900
atataaaaca atttgtatgg tatacacctc caacttttat gatagctgtt ttccttccaa 960
ttgttgtcct gatatttaaa agcatactat tcctgccatg cttgaggaag aagatactga 1020
agattagaca tggttgggaa gacgtcacca aaattaacaa aactgagata tgttcccagt 1080
tgtagaatta ctgtttacac acatttttgt tcaatattga tatattttat caccaacatt 1140
tcaagtttgt atttgttaat aaaatgatta ttcaaggaaa aaaaaaaaaa aaaaa 1195
<210>36
<211>3414
<212>DNA
<213>人
<400>36
gcttacacag tatggccggc gacattagct agcgctcgct ctactctctc taacgggaaa 60
gcagcggaat acaagagact gaactgtatc tgcctctatt tccaaaagac tcacgttcaa 120
ctttcgctca cacaaagccg ggaaaatttt attagtcctt tttttaaaaa aagttaatat 180
aaaattatag caaaaaaaaa aaggaacctg aactttagta acacagctgg aacaatcgca 240
gcggcggcgg cagcggcggg agaagaggtt taatttagtt gattttctgt ggttgttggt 300
tgttcgctag tctcacggtg atggaagctg cacatttttt cgaagggacc gagaagctgc 360
tggaggtttg gttctcccgg cagcagcccg acgcaaacca aggatctggg gatcttcgca 420
ctatcccaag atctgagtgg gacatacttt tgaaggatgt gcaatgttca atcataagtg 480
tgacaaaaac tgacaagcag gaagcttatg tactcagtga gagtagcatg tttgtctcca 540
agagacgttt cattttgaag agatgtggta ccaccctctt gctgaaagca ctggttcccc 600
tgttgaagct tgctagggat tacagtgggt ttgactcaat tcaaagcttc ttttattctc 660
gtaagaattt catgaagcct tctcaccaag ggtacccaca ccggaatttc caggaagaaa 720
tagagtttct taatgcaatt ttcccaaatg gagcaggata ttgtatggga cgtatgaatt 780
ctgactgttg gtacttatat actctggatt tcccagagag tcgggtaatc agtcagccag 840
atcaaacctt ggaaattctg atgagtgagc ttgacccagc agttatggac cagttctaca 900
tgaaagatgg tgttactgca aaggatgtca ctcgtgagag tggaattcgt gacctgatac 960
caggttctgt cattgatgcc acaatgttca atccttgtgg gtattcgatg aatggaatga 1020
aatcggatgg aacttattgg actattcaca tcactccaga accagaattt tcttatgtta 1080
gctttgaaac aaacttaagt cagacctcct atgatgacct gatcaggaaa gttgtagaag 1140
tcttcaagcc aggaaaattt gtgaccacct tgtttgttaa tcagagttct aaatgtcgca 1200
cagtgcttgc ttcgccccag aagattgaag gttttaagcg tcttgattgc cagagtgcta 1260
tgttcaatga ttacaatttt gtttttacca gttttgctaa gaagcagcaa caacagcaga 1320
gttgattaag aaaaatgaag aaaaaacgca aaaagagaac acatgtagaa ggtggtggat 1380
gctttctaga tgtcgatgct gggggcagtg ctttccataa ccaccactgt gtagttgcag 1440
aaagccctag atgtaatgat agtgtaatca ttttgaattg tatgcattat tatatcaagg 1500
agttagatat cttgcatgaa tgctctcttc tgtgtttagg tattctctgc cactcttgct 1560
gtgaaattga agtggatgta gaaaaaacct tttactatat gaaactttac aacacttgtg 1620
aaagcaactc aatttggttt atgcacagtg taatatttct ccaagtatca tccaaaattc 1680
cccacagaca aggctttcgt cctcattagg tgttggcctc agcctaaccc tctaggactg 1740
ttctattaaa ttgctgccag aattttacat ccagttacct ccactttcta gaacatattc 1800
tttactaatg ttattgaaac caatttctac ttcatactga tgtttttgga aacagcaatt 1860
aaagtttttc ttccatagtt gagtccttag aaaatgattc cagttactca ttttgcatat 1920
tgctatttaa cattattgga ccctgcattt atagtccttt gatttcttcc ctctccctgg 1980
tgtctccccc aagaccccaa ataaagcaat accctgttaa cactgtgggt ttatatacta 2040
attctatacc ccagatgggg aattaggggg gagatggtcc ctgggcttaa tattctttaa 2100
agggcatggg aatttagcct ctcttttatt gtaatgtgct cttttggaaa atagttggtt 2160
agcagggaga ccagagttgt agattgagat tgggtgtact ggctgttctg tggaaaacat 2220
acattctgtg ttcctcgaat aagtgaaatt gagcttctaa tgagatgcac ccctttacta 2280
acttgatgat gatataaaat tcatttttat ttagttaatt accagagaga tttagcataa 2340
ttttgcttct ggattcagta aatcaagtca gcttggatca ttcaccttaa cttttccttt 2400
agcagccctt tccactagtt tcccattaag tagtgttcta taaactttga tccaaagcag 2460
aatcaatgtc ttttccatct cgtgacttaa agttctgtga ctgtgatgca tgtgagtgtt 2520
ccgacttcat ctgttcctct taactacggt gtttccctta ccgatcggca ttcataggat 2580
gaaatgaatg actgtcccag aatgagaatt tgtccagatt attcagataa acatcataaa 2640
gagaataaca ttataaataa gtagaatatg aataaataga ataataaaat tccaaaatac 2700
tcaatgggaa atgactagta atataggctt tcaagagttg gtacctttac gtatatttgc 2760
agattctctg ggattttaag gaactgagaa aacagaaaag ttgactaaat tttatatttc 2820
ttgtcctcta aatattttga taattcctgg attgatgcag tgatgttttt cgttccttgt 2880
atttataaat gaaaaccttt ttttggtgtt tctaaaccta aaatctactt ggtttgaaat 2940
caagtggttg gaacactgtt tgacttttat ttgaagcatg ttgttgattg aaaatttcat 3000
tgaggaagtt ttcaatcagt gtgatcagtt tgattctgta atgagcacag cacctaatat 3060
tttgaggagc tctgttttga ggaccaatgc ttaaggtgga ccttgttgct aaacaatatc 3120
ccaatagatt tgttgacttg aggtctggtt tggttttgtt tttgttttgt tttggttttg 3180
ttttgtttcc caatagaatt aagaattcta atgttgaaaa actgtataaa tttttatggg 3240
acaaagccta gaaaagagaa atgtagtttg aatcataatc taaatcatcg tatgatagga 3300
aggaaaagtt ttggtgccat aatttctcct ttcactggtg ttggacttaa atcagttgaa 3360
atgtatttct gtaccacaat ttacgcttca ataaaagttt aattgtctag tgag 3414
<210>37
<211>3287
<212>DNA
<213>人
<400>37
agactgaggc ggaggcagcc ccgcgccgcg ccggacccga gcatatttca ttttctgtca 60
ttggactttg agccattaga accatgagca actacagtgt gtcactggtt ggcccagctc 120
cttggggttt ccggctgcag ggcggtaagg atttcaacat gcctctgaca atctctagtc 180
taaaagatgg cggcaaggca gcccaggcaa atgtaagaat aggcgatgtg gttctcagca 240
ttgatggaat aaatgcacaa ggaatgactc atcttgaagc ccagaataag attaagggtt 300
gtacaggctc tttgaatatg actctgcaaa gagcatctgc tgcacccaag cctgagccgg 360
ttcctgttca aaagggagaa cctaaagaag tagttaaacc tgtgcccatt acatctcctg 420
ctgtgtccaa agtcacttcc acaaacaaca tggcctacaa taaggcacca cggccttttg 480
gttctgtgtc ttcaccaaaa gtcacatcca tcccatcacc atcgtctgcc ttcaccccag 540
cccatgcgac cacctcatca catgcttccc cttcacccgt ggctgccgtc actcctcccc 600
tgttcgctgc atctggactg catgctaatg ccaatcttag tgctgaccag tctccatctg 660
cactgagcgc tggtaaaact gcagttaatg tcccacggca gcccacagtc accagcgtgt 720
gttccgagac ttctcaggag ctagcagagg gacagagaag aggatcccag ggtgacagta 780
aacagcaaaa tggcccacca agaaaacaca ttgtggagcg ctatacagag ttttatcatg 840
tacccactca cagtgatgcc agcaagaaga gactgattga ggatactgaa gactggcgtc 900
caagaactgg aacaactcag tctcgctctt tccgaatcct tgcccagatc actgggactg 960
aacatttgaa agaatctgaa gccgataata caaagaaggc aaataactct caggagcctt 1020
ctccgcagtt ggcttccttg gtagcttcca cacggagcat gcccgagagc ctggacagcc 1080
caacctctgg cagaccaggg gttaccagcc tcacaactgc agctgccttc aagcctgtag 1140
gatccactgg cgtcatcaag tcaccaagct ggcaacggcc aaaccaagga gtaccttcca 1200
ctggaagaat ctcaaacagc gctacttact caggatcagt ggcaccagcc aactcagctt 1260
tgggacaaac ccagccaagt gaccaggaca ctttagtgca aagagctgag cacattccag 1320
cagggaaacg aactccgatg tgcgcccatt gtaaccaggt catcagagga ccattcttag 1380
tggcactggg gaaatcttgg cacccagaag aattcaactg cgctcactgc aaaaatacaa 1440
tggcctacat tggatttgta gaggagaaag gagccctgta ttgtgagctg tgctatgaga 1500
aattctttgc ccctgaatgt ggtcgatgcc aaaggaagat ccttggagaa gtcatcaatg 1560
cgttgaaaca aacttggcat gtttcctgtt ttgtgtgtgt agcctgtgga aagcccattc 1620
ggaacaatgt ttttcacttg gaggatggtg aaccctactg tgagactgat tattatgccc 1680
tctttggtac tatatgccat ggatgtgaat ttcccataga agctggtgac atgttcctgg 1740
aagctctggg ctacacctgg catgacactt gctttgtatg ctcagtgtgt tgtgaaagtt 1800
tggaaggtca gacctttttc tccaagaagg acaagcccct gtgtaagaaa catgctcatt 1860
ctgtgaattt ttgaaagtca acagttcagg agaagagaag gaatttgaag agaaaaagga 1920
aaattaaaat tactaattaa tttttagatt caatatttat atggagtttt gaaaaataat 1980
agtggccctg aaggaataaa ttccagcttt aaaaaccaag tctgaggaaa tatttggctt 2040
cataaagtaa agagacggtt tggcatttat tattactttt tcctgtattt tatgcccata 2100
aaataagctt tataaaaacc aatttcctga tggactatta aattcatctt agaataaatt 2160
agtgaagaat ttaattttag aataaataat ccaatctgaa ataattatac cttctttcct 2220
tgttaggtag ttatgagtaa atctgcaaaa ggcaatgaaa atgccttaaa ttttatcaat 2280
aacagaatta ttgtatttaa aaaaaaacta atacttatct ttaaaatagt aaataggatt 2340
ttaaacagag aattttatca gtaataggtg tcagttttta aaaaattgct tgtaggctga 2400
gcgcggtggc tcacgcctgt aatcccagca ctttgggagg ccaaggtggg tggaccacat 2460
gaggtcagga gtttgagatc agcctggcca acatggtgaa accccatctc tactaaaaat 2520
acaaaaatta gccggacgca gtggcacgcg cctgtaatcc cagctactca agaggctgag 2580
gcacgagaat cacttgaacc cgggagggag aggttgcagt gagccaagat cgtaccactg 2640
cactccagcc tgggtgacag agtgagactc cgtctccaaa aaaaaacttt gcttgtatat 2700
tatttttgcc ttacagtgga tcattctagt aggaaaggac aataagattt tttatcaaaa 2760
tgtgtcatgc cagtaagaga tgttatattc ttttcttatt tcttccccac ccaaaaataa 2820
gctaccatat agcttataag tctcaaattt ttgcctttta ctaaaatgtg attgtttctg 2880
ttcattgtgt atgcttcatc acctatatta ggcaaattcc attttttccc ttgcgctaag 2940
gtaaagattt aattaaataa ttttggcctc tcatagtttt ctctctcttt aaagagaata 3000
aatagagggc caggtgtggt ggctcacgcc tgtgatccca gcactttggg aggccaagac 3060
gggcggatca tgaggtcaag agatcaagat catcctggcc aacatggtga aaccctgtct 3120
ctactaaaaa tacaaaaatg agctgggcat ggtggggcgt gcctgtagtc ccatgtactt 3180
gggaggctga ggcaggaaaa ttcttgaacc caggagacgg aagttgcagt gagctgagat 3240
cacaccactg cactccagcc tggtgacaga gcaagactcc ggctctt 3287
<210>38
<211>1254
<212>DNA
<213>人
<400>38
atggcagtgg agaccacggt ccacactcac ctctctgcgt ctccaccgca gggctctccc 60
tacgaccaca cacccggcat ggcgggctcc ttggggtacc atccttacgc ggcgcccctg 120
ggatcgtacc cttacgggga cccagcgtac cggaagaacg ccacaaggga cgccacggct 180
accctcaagg cctggctcaa cgagcaccgc aagaacccct accccaccaa gggcgagaag 240
atcatgctgg ccatcatcac caagatgacc ctcacccagg tgtccacctg gttcgccaac 300
gcgcgccggc gcctcaagaa agagaataaa atgacgtgga cgccgcggaa ccgcagcgag 360
gacgaggaag aggaggagaa cattgacctg gagaagaacg acgaggacga gccccagaag 420
cccgaggaca agggcgaccc cgagggcccc gaagcaggag gagctgagca gaaggcggct 480
tcgggctgcg aacggcttca gggaccaccc acccctgcag gcaaggagac ggagggcagc 540
ctcagcgact cggattttaa ggagccgccc tcggagggcc gcctcgacgc gctgcagggc 600
cccccccgca ccggcgggcc ctccccggct gggccagcgg cggcgcggct ggcggaggac 660
ccggcccctc actaccccgc cggagcgccg gcgcccggcc cgcatccagc cgcgggcgag 720
gtgcctccgg gtcccggcgg gccctcggtt atccattcgc cgcctccgcc gccgcctcct 780
gcggtgctcg ccaagcccaa actgtggtct ttggcagaga tcgccacatt gtcggacaag 840
gtcaaggacg ggggcggcgg gaacgagggc tctccatgcc caccgtgtcc cgggcccata 900
gccgggcaag ccctaggagg cagccgggcg tcgccggccc cggcgccgtc acgctcgccc 960
tcggcgcagt gtccttttcc aggcgggacg gtgctgtccc ggcctctcta ctacaccgcg 1020
cccttctatc ccggctacac gaactatggc tccttcggac accttcatgg ccacccgggg 1080
cccgggccag gccccacaac cggtccgggg tctcatttca atggattaaa ccagaccgtg 1140
ttgaaccgag cggacgcttt ggctaaagac ccgaaaatgt tgcggagcca gtctcagcta 1200
gacctgtgca aagactctcc ctatgaattg aagaaaggta tgtccgacat ttaa 1254
<210>39
<211>2560
<212>DNA
<213>人
<400>39
gaattccggc cagaagaaat ctggcctcgg aacacgccat tctccgcgcc gcttccaata 60
accactaaca tccctaacga gcatccgagc cgagggctct gctcggaaat cgtcctggcc 120
caactcggcc cttcgagctc tcgaagatta ccgcatctat tttttttttc ttttttttct 180
tttcctagcg cagataaagt gagcccggaa agggaaggag ggggcgggga caccattgcc 240
ctgaaagaat aaataagtaa ataaacaaac tggctcctcg ccgcagctgg acgcggtcgg 300
ttgagtccag gttgggtcgg acctgaaccc ctaaaagcgg aaccgcctcc cgccctcgcc 360
atcccggagc tgagtcgccg gcggcggtgg ctgctgccag acccggagtt tcctctttca 420
ctggatggag ctgaactttg ggcggccaga gcagcacagc tgtccgggga tcgctgcacg 480
ctgagctccc tcggcaagac ccagcggcgg ctcgggattt ttttgggggg gcggggacca 540
gccccgcgcc ggcaccatgt tcctggcgac cctgtacttc gcgctgccgc tcttggactt 600
gctcctgtcg gccgaagtga gcggcggaga ccgcctggat tgcgtgaaag ccagtgatca 660
gtgcctgaag gagcagagct gcagcaccaa gtaccgcacg ctaaggcagt gcgtggcggg 720
caaggagacc aacttcagcc tggcatccgg cctggaggcc aaggatgagt gccgcagcgc 780
catggaggcc ctgaagcaga agtcgctcta caactgccgc tgcaagcggg gtatgaagaa 840
ggagaagaac tgcctgcgca tttactggag catgtaccag agcctgcagg gaaatgatct 900
gctggaggat tccccatatg aaccagttaa cagcagattg tcagatatat tccgggtggt 960
cccattcata tcagatgttt ttcagcaagt ggagcacatt cccaaaggga acaactgcct 1020
ggatgcagcg aaggcctgca acctcgacga catttgcaag aagtacaggt cggcgtacat 1080
caccccgtgc accaccagcg tgtccaacga tgtctgcaac cgccgcaagt gccacaaggc 1140
cctccggcag ttctttgaca aggtcccggc caagcacagc tacggaatgc tcttctgctc 1200
ctgccgggac atcgcctgca cagagcggag gcgacagacc atcgtgcctg tgtgctccta 1260
tgaagagagg gagaagccca actgtttgaa tttgcaggac tcctgcaaga cgaattacat 1320
ctgcagatct cgccttgcgg atttttttac caactgccag ccagagtcaa ggtctgtcag 1380
cagctgtcta aaggaaaact acgctgactg cctcctcgcc tactcggggc ttattggcac 1440
agtcatgacc cccaactaca tagactccag tagcctcagt gtggccccat ggtgtgactg 1500
cagcaacagt gggaacgacc tagaagagtg cttgaaattt ttgaatttct tcaaggacaa 1560
tacatgtctt aaaaatgcaa ttcaagcctt tggcaatggc tccgatgtga ccgtgtggca 1620
gccagccttc ccagtacaga ccaccactgc cactaccacc actgccctcc gggttaagaa 1680
caagcccctg gggccagcag ggtctgagaa tgaaattccc actcatgttt tgccaccgtg 1740
tgcaaattta caggcacaga agctgaaatc caatgtgtcg ggcaatacac acctctgtat 1800
ttccaatggt aattatgaaa aagaaggtct cggtgcttcc agccacataa ccacaaaatc 1860
aatggctgct cctccaagct gtggtctgag cccactgctg gtcctggtgg taaccgctct 1920
gtccacccta ttatctttaa cagaaacatc atagctgcat taaaaaaata caatatggac 1980
atgtaaaaag acaaaaacca agttatctgt ttcctgttct cttgtatagc tgaaattcca 2040
gtttaggagc tcagttgaga aacagttcca ttcaactgga acattttttt ttttcctttt 2100
aagaaagctt cttgtgatcc ttcggggctt ctgtgaaaaa cctgatgcag tgctccatcc 2160
aaactcagaa ggctttggga tatgctgtat tttaaaggga cagtttgtaa cttgggctgt 2220
aaagcaaact ggggctgtgt tttcgatgat gatgatcatc atgatcatga tgattttaac 2280
agttttactt ctggcctttc ctagctagag aaggagttaa tatttctaag gtaactccca 2340
tatctccttt aatgacattg atttctaatg atataaattt cagcctacat tgatgccaag 2400
cttttttgcc acaaagaaga ttcttaccaa gagtgggctt tgtggaaaca gctggtactg 2460
atgttcacct ttatatatgt actagcattt tccacgctga tgtttatgta ctgtaaacag 2520
ttctgcactc ttgtacaaaa gaaaaaacca cccggaattc 2560
<210>40
<211>2560
<212>DNA
<213>人
<400>40
gaattccggc cagaagaaat ctggcctcgg aacacgccat tctccgcgcc gcttccaata 60
accactaaca tccctaacga gcatccgagc cgagggctct gctcggaaat cgtcctggcc 120
caactcggcc cttcgagctc tcgaagatta ccgcatctat tttttttttc ttttttttct 180
tttcctagcg cagataaagt gagcccggaa agggaaggag ggggcgggga caccattgcc 240
ctgaaagaat aaataagtaa ataaacaaac tggctcctcg ccgcagctgg acgcggtcgg 300
ttgagtccag gttgggtcgg acctgaaccc ctaaaagcgg aaccgcctcc cgccctcgcc 360
atcccggagc tgagtcgccg gcggcggtgg ctgctgccag acccggagtt tcctctttca 420
ctggatggag ctgaactttg ggcggccaga gcagcacagc tgtccgggga tcgctgcacg 480
ctgagctccc tcggcaagac ccagcggcgg ctcgggattt ttttgggggg gcggggacca 540
gccccgcgcc ggcaccatgt tcctggcgac cctgtacttc gcgctgccgc tcttggactt 600
gctcctgtcg gccgaagtga gcggcggaga ccgcctggat tgcgtgaaag ccagtgatca 660
gtgcctgaag gagcagagct gcagcaccaa gtaccgcacg ctaaggcagt gcgtggcggg 720
caaggagacc aacttcagcc tggcatccgg cctggaggcc aaggatgagt gccgcagcgc 780
catggaggcc ctgaagcaga agtcgctcta caactgccgc tgcaagcggg gtatgaagaa 840
ggagaagaac tgcctgcgca tttactggag catgtaccag agcctgcagg gaaatgatct 900
gctggaggat tccccatatg aaccagttaa cagcagattg tcagatatat tccgggtggt 960
cccattcata tcagatgttt ttcagcaagt ggagcacatt cccaaaggga acaactgcct 1020
ggatgcagcg aaggcctgca acctcgacga catttgcaag aagtacaggt cggcgtacat 1080
caccccgtgc accaccagcg tgtccaacga tgtctgcaac cgccgcaagt gccacaaggc 1140
cctccggcag ttctttgaca aggtcccggc caagcacagc tacggaatgc tcttctgctc 1200
ctgccgggac atcgcctgca cagagcggag gcgacagacc atcgtgcctg tgtgctccta 1260
tgaagagagg gagaagccca actgtttgaa tttgcaggac tcctgcaaga cgaattacat 1320
ctgcagatct cgccttgcgg atttttttac caactgccag ccagagtcaa ggtctgtcag 1380
cagctgtcta aaggaaaact acgctgactg cctcctcgcc tactcggggc ttattggcac 1440
agtcatgacc cccaactaca tagactccag tagcctcagt gtggccccat ggtgtgactg 1500
cagcaacagt gggaacgacc tagaagagtg cttgaaattt ttgaatttct tcaaggacaa 1560
tacatgtctt aaaaatgcaa ttcaagcctt tggcaatggc tccgatgtga ccgtgtggca 1620
gccagccttc ccagtacaga ccaccactgc cactaccacc actgccctcc gggttaagaa 1680
caagcccctg gggccagcag ggtctgagaa tgaaattccc actcatgttt tgccaccgtg 1740
tgcaaattta caggcacaga agctgaaatc caatgtgtcg ggcaatacac acctctgtat 1800
ttccaatggt aattatgaaa aagaaggtct cggtgcttcc agccacataa ccacaaaatc 1860
aatggctgct cctccaagct gtggtctgag cccactgctg gtcctggtgg taaccgctct 1920
gtccacccta ttatctttaa cagaaacatc atagctgcat taaaaaaata caatatggac 1980
atgtaaaaag acaaaaacca agttatctgt ttcctgttct cttgtatagc tgaaattcca 2040
gtttaggagc tcagttgaga aacagttcca ttcaactgga acattttttt ttttcctttt 2100
aagaaagctt cttgtgatcc ttcggggctt ctgtgaaaaa cctgatgcag tgctccatcc 2160
aaactcagaa ggctttggga tatgctgtat tttaaaggga cagtttgtaa cttgggctgt 2220
aaagcaaact ggggctgtgt tttcgatgat gatgatcatc atgatcatga tgattttaac 2280
agttttactt ctggcctttc ctagctagag aaggagctaa tatttctaag gtaactccca 2340
tatctccttt aatgacattg atttctaatg atataaattt cagcctacat tgatgccaag 2400
cttttttgcc acaaagaaga ttcttaccaa gagtgggctt tgtggaaaca gctggtactg 2460
atgttcacct ttatatatgt actagcattt tccacgctga tgtttatgta ctgtaaacag 2520
ttctgcactc ttgtacaaaa gaaaaaacca cccggaattc 2560
<210>41
<211>2439
<212>DNA
<213>人
<400>41
cagcacccag ctccccgcca ccgccatggt ccccgacacc gcctgcgttc ttctgctcac 60
cctggctgcc ctcggcgcgt ccggacaggg ccagagcccg ttgggctcag acctgggccc 120
gcagatgctt cgggaactgc aggaaaccaa cgcggcgctg caggacgtgc gggactggct 180
gcggcagcag gtcagggaga tcacgttcct gaaaaacacg gtgatggagt gtgacgcgtg 240
cgggatgcag cagtcagtac gcaccggcct acccagcgtg cggcccctgc tccactgcgc 300
gcccggcttc tgcttccccg gcgtggcctg catccagacg gagagcggcg gccgctgcgg 360
cccctgcccc gcgggcttca cgggcaacgg ctcgcactgc accgacgtca acgagtgcaa 420
cgcccacccc tgcttccccc gagtccgctg tatcaacacc agcccggggt tccgctgcga 480
ggcttgcccg ccggggtaca gcggccccac ccaccagggc gtggggctgg ctttcgccaa 540
ggccaacaag caggtttgca cggacatcaa cgagtgtgag accgggcaac ataactgcgt 600
ccccaactcc gtgtgcatca acacccgggg ctccttccag tgcggcccgt gccagcccgg 660
cttcgtgggc gaccaggcgt ccggctgcca gcgcggcgca cagcgcttct gccccgacgg 720
ctcgcccagc gagtgccacg agcatgcaga ctgcgtccta gagcgcgatg gctcgcggtc 780
gtgcgtgtgt cgcgttggct gggccggcaa cgggatcctc tgtggtcgcg acactgacct 840
agacggcttc ccggacgaga agctgcgctg cccggagccg cagtgccgta aggacaactg 900
cgtgactgtg cccaactcag ggcaggagga tgtggaccgc gatggcatcg gagacgcctg 960
cgatccggat gccgacgggg acggggtccc caatgaaaag gacaactgcc cgctggtgcg 1020
gaacccagac cagcgcaaca cggacgagga caagtggggc gatgcgtgcg acaactgccg 1080
gtcccagaag aacgacgacc aaaaggacac agaccaggac ggccggggcg atgcgtgcga 1140
cgacgacatc gacggcgacc ggatccgcaa ccaggccgac aactgcccta gggtacccaa 1200
ctcagaccag aaggacagtg atggcgatgg tataggggat gcctgtgaca actgtcccca 1260
gaagagcaac ccggatcagg cggatgtgga ccacgacttt gtgggagatg cttgtgacag 1320
cgatcaagac caggatggag acggacatca ggactctcgg gacaactgtc ccacggtgcc 1380
taacagtgcc caggaggact cagaccacga tggccagggt gatgcctgcg acgacgacga 1440
cgacaatgac ggagtccctg acagtcggga caactgccgc ctggtgccta accccggcca 1500
ggaggacgcg gacagggacg gcgtgggcga cgtgtgccag gacgactttg atgcagacaa 1560
ggtggtagac aagatcgacg tgtgtccgga gaacgctgaa gtcacgctca ccgacttcag 1620
ggccttccag acagtcgtgc tggacccgga gggtgacgcg cagattgacc ccaactgggt 1680
ggtgctcaac cagggaaggg agatcgtgca gacaatgaac agcgacccag gcctggctgt 1740
gggttacact gccttcaatg gcgtggactt cgagggcacg ttccatgtga acacggtcac 1800
ggatgacgac tatgcgggct tcatctttgg ctaccaggac agctccagct tctacgtggt 1860
catgtggaag cagatggagc aaacgtattg gcaggcgaac cccttccgtg ctgtggccga 1920
gcctggcatc caactcaagg ctgtgaagtc ttccacaggc cccggggaac agctgcggaa 1980
cgctctgtgg catacaggag acacagagtc ccaggtgcgg ctgctgtgga aggacccgcg 2040
aaacgtgggt tggaaggaca agaagtccta tcgttggttc ctgcagcacc ggccccaagt 2100
gggctacatc agggtgcgat tctatgaggg ccctgagctg gtggccgaca gcaacgtggt 2160
cttggacaca accatgcggg gtggccgcct gggggtcttc tgcttctccc aggagaacat 2220
catctgggcc aacctgcgtt accgctgcaa tgacaccatc ccagaggact atgagaccca 2280
tcagctgcgg caagcctagg gaccagggtg aggacccgcc ggatgacagc caccctcacc 2340
gcggctggat gggggctctg cacccagccc aaggggtggc cgtcctgagg gggaagtgag 2400
aagggctcag agaggacaaa ataaagtgtg tgtgcaggg 2439
<210>42
<211>2439
<212>DNA
<213>人
<400>42
cagcacccag ctccccgcca ccgccatggt ccccgacacc gcctgcgttc ttctgctcac 60
cctggctgcc ctcggcgcgt ccggacaggg ccagagcccg ttgggctcag acctgggccc 120
gcagatgctt cgggaactgc aggaaaccaa cgcggcgctg caggacgtgc gggactggct 180
gcggcagcag gtcagggaga tcacgttcct gaaaaacacg gtgatggagt gtgacgcgtg 240
cgggatgcag cagtcagtac gcaccggcct acccagcgtg cggcccctgc tccactgcgc 300
gcccggcttc tgcttccccg gcgtggcctg catccagacg gagagcggcg gccgctgcgg 360
cccctgcccc gcgggcttca cgggcaacgg ctcgcactgc accgacgtca acgagtgcaa 420
cgcccacccc tgcttccccc gagtccgctg tatcaacacc agcccggggt tccgctgcga 480
ggcttgcccg ccggggtaca gcggccccac ccaccagggc gtggggctgg ctttcgccaa 540
ggccaacaag caggtttgca cggacatcaa cgagtgtgag accgggcaac ataactgcgt 600
ccccaactcc gtgtgcatca acacccgggg ctccttccag tgcggcccgt gccagcccgg 660
cttcgtgggc gaccaggcgt ccggctgcca gcgcggcgca cagcgcttct gccccgacgg 720
ctcgcccagc gagtgccacg agcatgcaga ctgcgtccta gagcgcgatg gctcgcggtc 780
gtgcgtgtgt cgcgttggct gggccggcaa cgggatcctc tgtggtcgcg acactgacct 840
agacggcttc ccggacgaga agctgcgctg cccggagccg cagtgccgta aggacaactg 900
cgtgactgtg cccaactcag ggcaggagga tgtggaccgc gatggcatcg gagacgcctg 960
cgatccggat gccgacgggg acggggtccc caatgaaaag gacaactgcc cgctggtgcg 1020
gaacccagac cagcgcaaca cggacgagga caagtggggc gatgcgtgcg acaactgccg 1080
gtcccagaag aacgacgacc aaaaggacac agaccaggac ggccggggcg atgcgtgcga 1140
cgacgacatc gacggcgacc ggatccgcaa ccaggccgac aactgcccta gggtacccaa 1200
ctcagaccag aaggacagtg atggcgatgg tataggggat gcctgtgaca actgtcccca 1260
gaagagcaac ccggatcagg cggatgtgga ccacgacttt gtgggagatg cttgtgacag 1320
cgatcaagac caggatggag acggacatca ggactctcgg gacaactgtc ccacggtgcc 1380
taacagtgcc caggaggact cagaccacga tggccagggt gatgcctgcg acgacgacga 1440
cgacaatgac ggagtccctg acagtcggga caactgccgc ctggtgccta accccggcca 1500
ggaggacgcg gacagggacg gcgtgggcga cgtgtgccag gacgactttg atgcagacaa 1560
ggtggtagac aagatcgacg tgtgtccgga gaacgctgaa gtcacgctca ccgacttcag 1620
ggccttccag acagtcgtgc tggacccgga gggtgacgcg cagattgacc ccaactgggt 1680
ggtgctcaac cagggaaggg agatcgtgca gacaatgaac agcgacccag gcctggctgt 1740
gggttacact gccttcaatg gcgtggactt cgagggcacg ttccatgtga acacggtcac 1800
ggatgacgac tatgcgggct tcatctttgg ctaccaggac agctccagct tctacgtggt 1860
catgtggaag cagatggagc aaacgtattg gcaggcgaac cccttccgtg ctgtggccga 1920
gcctggcatc caactcaagg ctgtgaagtc ttccacaggc cccggggaac agctgcggaa 1980
cgctctgtgg catacaggag acacagagtc ccaggtgcgg ctgctgtgga aggacccgcg 2040
aaacgtgggt tggaaggaca agaagtccta tcgttggttc ctgcagcacc ggccccaagt 2100
gggctacatc agggtgcgat tctatgaggg ccctgagctg gtggccgaca gcaacgtggt 2160
cttggacaca accatgcggg gtggccgcct gggggtcttc tgcttctccc aggagaacat 2220
catctgggcc aacctgcgtt accgctgcaa tgacaccatc ccagaggact atgagaccca 2280
tcagctgcgg caagcctagg gaccagggtg aggacccgcc ggatgacagc caccctcacc 2340
gcggctggat gggggctctg cacccagccc aaggggtggc cgtcctgagg gggaagtgag 2400
aagggctcag agaggacaaa ataaagtgtg tgtgcaggg 2439
<210>43
<211>1365
<212>DNA
<213>人
<400>43
ctccagccat tggtgtctgt gtcattacta atagagtctt gtaaacactc gttaatcacg 60
gaagccgccg gcctggggct ccgcacgcca gcctgtgcgg gtcttccccg cctctgcagc 120
ctagtgggaa ggaggtggga ggaaagaagg aagaaaggga gggagggagg aggcaggcca 180
gagggaggga ccgcctcgga ggcagaagag ccgcgaggag ccagcggagc accgcgggct 240
ggggcgcagc cacccgccgc tcctcgagtc ccctcgcccc tttcccttcg tgccccccgg 300
cagcctccag cgtcggtccc caggcagcat ggtgaggtct gctcccggtc cctcgccacc 360
atgtacgtga gctacctcct ggacaaggac gtgagcatgt accctagctc cgtgcgccac 420
tctggcggcc tcaacctggc gccgcagaac ttcgtcagcc ccccgcagta cccggactac 480
ggcggttacc acgtggcggc cgcagctgca gcggcagcga acttggacag cgcgcagtcc 540
ccggggccat cctggccggc agcgtatggc gccccactcc gggaggactg gaatggctac 600
gcgcccggag gcgccgcggc cgccgccaac gccgtggctc acggcctcaa cggtggctcc 660
ccggccgcag ccatgggcta cagcagcccc gcagactacc atccgcacca ccacccgcat 720
caccacccgc accacccggc cgcggcgcct tcctgcgctt ctgggctgct gcaaacgctc 780
aaccccggcc ctcctgggcc cgccgccacc gctgccgccg agcagctgtc tcccggcggc 840
cagcggcgga acctgtgcga gtggatgcgg aagccggcgc agcagtccct cggcagccaa 900
gtgaaaacca ggacgaaaga caaatatcga gtggtgtaca cggaccacca gcggctggag 960
ctggagaagg agtttcacta cagtcgctac atcaccatcc ggaggaaagc cgagctagcc 1020
gccacgctgg ggctctctga gaggcaggtt aaaatctggt ttcagaaccg cagagcaaag 1080
gagaggaaaa tcaacaagaa gaagttgcag cagcaacagc agcagcagcc accacagccg 1140
cctccgccgc caccacagcc tccccagcct cagccaggtc ctctgagaag tgtcccagag 1200
cccttgagtc cggtgtcttc cctgcaagcc tcagtgtctg gctctgtccc tggggttctg 1260
gggccaactg ggggggtgct aaaccccacc gtcacccagt gacccaccgg ggttctgcag 1320
cggcagagca attccaggct gagccatgag gagcgtggac tctgctagac tcctcaggag 1380
agacc 1385
<210>44
<211>4098
<212>DNA
<213>人
<400>44
ggtggcctct gtggccgtcc aggctagcgg cggcccgcag gcggcgggga gaaagactct 60
ctcacctggt cttgcggctg tggccaccgc cggccagggg tgtggagggc gtgctgccgg 120
agacgtccgc cgggctctgc agttccgccg ggggtcgggc agctatggag ccgcggccca 180
cggcgccctc ctccggcgcc ccgggactgg ccggggtcgg ggagacgccg tcagccgctg 240
cgctggccgc agccagggtg gaactgcccg gcacggctgt gccctcggtg ccggaggatg 300
ctgcgcccgc gagccgggac ggcggcgggg tccgcgatga gggccccgcg gcggccgggg 360
acgggctggg cagacccttg gggcccaccc cgagccagag ccgtttccag gtggacctgg 420
tttccgagaa cgccgggcgg gccgctgctg cggcggcggc ggcggcggcg gcagcggcgg 480
cggctggtgc tggggcgggg gccaagcaga cccccgcgga cggggaagcc agcggcgaga 540
gcgagccagc taaaggcagc gaggaagcca agggccgctt ccgcgtgaac ttcgtggacc 600
cagctgcctc ctcgtcggct gaagacagcc tgtcagatgc tgccggggtc ggagtcgacg 660
ggcccaacgt gagcttccag aacggcgggg acacggtgct gagcgagggc agcagcctgc 720
actccggcgg cggcggcggc agtgggcacc accagcacta ctattatgat acccacacca 780
acacctacta cctgcgcacc ttcggccaca acaccatgga cgctgtgccc aggatcgatc 840
actaccggca cacagccgcg cagctgggcg agaagctgct ccggcctagc ctggcggagc 900
tccacgacga gctggaaaag gaaccttttg aggatggctt tgcaaatggg gaagaaagta 960
ctccaaccag agatgctgtg gtcacgtata ctgcagaaag taaaggagtc gtgaagtttg 1020
gctggatcaa gggtgtatta gtacgttgta tgttaaacat ttggggtgtg atgcttttca 1080
ttagattgtc atggattgtg ggtcaagctg gaataggtct atcagtcctt gtaataatga 1140
tggccactgt tgtgacaact atcacaggat tgtctacttc agcaatagca actaatggat 1200
ttgtaagagg aggaggagca tattatttaa tatctagaag tctagggcca gaatttggtg 1260
gtgcaattgg tctaatcttc gcctttgcca acgctgttgc agttgctatg tatgtggttg 1320
gatttgcaga aaccgtggtg gagttgctta aggaacattc catacttatg atagatgaaa 1380
tcaatgatat ccgaattatt ggagccatta cagtcgtgat tcttttaggt atctcagtag 1440
ctggaatgga gtgggaagca aaagctcaga ttgttctttt ggtgatccta cttcttgcta 1500
ttggtgattt cgtcatagga acatttatcc cactggagag caagaagcca aaagggtttt 1560
ttggttataa atctgaaata tttaatgaga actttgggcc cgattttcga gaggaagaga 1620
ctttcttttc tgtatttgcc atcttttttc ctgctgcaac tggtattctg gctggagcaa 1680
atatctcagg tgatcttgca gatcctcagt cagccatacc caaaggaaca ctcctagcca 1740
ttttaattac tacattggtt tacgtaggaa ttgcagtatc tgtaggttct tgtgttgttc 1800
gagatgccac tggaaacgtt aatgacacta tcgtaacaga gctaacaaac tgtacttctg 1860
cagcctgcaa attaaacttt gatttttcat cttgtgaaag cagtccttgt tcctatggcc 1920
taatgaacaa cttccaggta atgagtatgg tgtcaggatt tacaccacta atttctgcag 1980
gtatattttc agccactctt tcttcagcat tagcatccct agtgagtgct cccaaaatat 2040
ttcaggctct atgtaaggac aacatctacc cagctttcca gatgtttgct aaaggttatg 2100
ggaaaaataa tgaacctctt cgtggctaca tcttaacatt cttaattgca cttggattca 2160
tcttaattgc tgaactgaat gttattgcac caattatctc aaacttcttc cttgcatcat 2220
atgcattgat caatttttca gtattccatg catcacttgc aaaatctcca ggatggcgtc 2280
ctgcattcaa atactacaac atgtggatat cacttcttgg agcaattctt tgttgcatag 2340
taatgttcgt cattaactgg tgggctgcat tgctaacata tgtgatagtc cttgggctgt 2400
atatttatgt tacctacaaa aaaccagatg tgaattgggg atcctctaca caagccctga 2460
cttacctgaa tgcactgcag cattcaattc gtctttctgg agtggaagac cacgtgaaaa 2520
actttaggcc acagtgtctt gttatgacag gtgctccaaa ctcacgtcca gctttacttc 2580
atcttgttca tgatttcaca aaaaatgttg gtttgatgat ctgtggccat gtacatatgg 2640
gtcctcgaag acaagccatg aaagagatgt ccatcgatca agccaaatat cagcgatggc 2700
ttattaagaa caaaatgaag gcattttatg ctccagtaca tgcagatgac ttgagagaag 2760
gtgcacagta tttgatgcag gctgctggtc ttggtcgtat gaagccaaacacacttgtcc 2820
ttggatttaa gaaagattgg ttgcaagcag atatgaggga tgtggatatg tatataaact 2880
tatttcatga tgcttttgac atacaatatg gagtagtggt tattcgccta aaagaaggtc 2940
tggatatatc tcatcttcaa ggacaagaag aattattgtc atcacaagag aaatctcctg 3000
gcaccaagga tgtggtagta agtgtggaat atagtaaaaa gtccgattta gatacttcca 3060
aaccactcag tgaaaaacca attacacaca aagttgagga agaggatggc aagactgcaa 3120
ctcaaccact gttgaaaaaa gaatccaaag gccctattgt gcctttaaat gtagctgacc 3180
aaaagcttct tgaagctagt acacagtttc agaaaaaaca aggaaagaat actattgatg 3240
tctggtggct ttttgatgat ggaggtttga ccttattgat accttacctt ctgacgacca 3300
agaaaaaatg gaaagactgt aagatcagag tattcattgg tggaaagata aacagaatag 3360
accatgaccg gagagcgatg gctactttgc ttagcaagtt ccggatagac ttttctgata 3420
tcatggttct aggagatatc aataccaaac caaagaaaga aaatattata gcttttgagg 3480
aaatcattga gccatacaga cttcatgaag atgataaaga gcaagatatt gcagataaaa 3540
tgaaagaaga tgaaccatgg cgaataacag ataatgagct tgaactttat aagaccaaga 3600
cataccggca gatcaggtta aatgagttat taaaggaaca ttcaagcaca gctaatatta 3660
ttgtcatgag tctcccagtt gcacgaaaag gtgctgtgtc tagtgctctc tacatggcat 3720
ggttagaagc tctatctaag gacctaccac caatcctcct agttcgtggg aatcatcaga 3780
gtgtccttac cttctattca taaatgttct atacagtgga cagccctcca gaatggtact 3840
tcagtgccta gtgtagtaac ctgaaatctt caatgacaca ttaacatcac aatggcgaat 3900
ggtgactttt ctttcacgat ttcattaatt tgaaagcaca caggaaagct tgctccattg 3960
ataacgtgta tggagacttc ggttttagtc aattccatat ctcaatctta atggtgattc 4020
ttctctgttg aactgaagtt tgtgagagta gttttccttt gctacttgaa tagcaataaa 4080
agcgtgttaa ctttttgg 4098
<210>45
<211>4098
<212>DNA
<213>人
<400>45
ggtggcctct gtggccgtcc aggctagcgg cggcccgcag gcggcgggga gaaagactct 60
ctcacctggt cttgcggctg tggccaccgc cggccagggg tgtggagggc gtgctgccgg 120
agacgtccgc cgggctctgc agttccgccg ggggtcgggc agctatggag ccgcggccca 180
cggcgccctc ctccggcgcc ccgggactgg ccggggtcgg ggagacgccg tcagccgctg 240
cgctggccgc agccagggtg gaactgcccg gcacggctgt gccctcggtg ccggaggatg 300
ctgcgcccgc gagccgggac ggcggcgggg tccgcgatga gggccccgcg gcggccgggg 360
acgggctggg cagacccttg gggcccaccc cgagccagag ccgtttccag gtggacctgg 420
tttccgagaa cgccgggcgg gccgctgctg cggcggcggc ggcggcggcg gcagcggcgg 480
cggctggtgc tggggcgggg gccaagcaga cccccgcgga cggggaagcc agcggcgaga 540
gcgagccagc taaaggcagc gaggaagcca agggccgctt ccgcgtgaac ttcgtggacc 600
cagctgcctc ctcgtcggct gaagacagcc tgtcagatgc tgccggggtc ggagtcgacg 660
ggcccaacgt gagcttccag aacggcgggg acacggtgct gagcgagggc agcagcctgc 720
actccggcgg cggcggcggc agtgggcacc accagcacta ctattatgat acccacacca 780
acacctacta cctgcgcacc ttcggccaca acaccatgga cgctgtgccc aggatcgatc 840
actaccggca cacagccgcg cagctgggcg agaagctgct ccggcctagc ctggcggagc 900
tccacgacga gctggaaaag gaaccttttg aggatggctt tgcaaatggg gaagaaagta 960
ctccaaccag agatgctgtg gtcacgtata ctgcagaaag taaaggagtc gtgaagtttg 1020
gctggatcaa gggtgtatta gtacgttgta tgttaaacat ttggggtgtg atgcttttca 1080
ttagattgtc atggattgtg ggtcaagctg gaataggtct atcagtcctt gtaataatga 1140
tggccactgt tgtgacaact atcacaggat tgtctacttc agcaatagca actaatggat 1200
ttgtaagagg aggaggagca tattatttaa tatctagaag tctagggcca gaatttggtg 1260
gtgcaattgg tctaatcttc gcctttgcca acgctgttgc agttgctatg tatgtggttg 1320
gatttgcaga aaccgtggtg gagttgctta aggaacattc catacttatg atagatgaaa 1380
tcaatgatat ccgaattatt ggagccatta cagtcgtgat tcttttaggt atctcagtag 1440
ctggaatgga gtgggaagca aaagctcaga ttgttctttt ggtgatccta cttcttgcta 1500
ttggtgattt cgtcatagga acatttatcc cactggagag caagaagcca aaagggtttt 1560
ttggttataa atctgaaata tttaatgaga actttgggcc cgattttcga gaggaagaga 1620
ctttcttttc tgtatttgcc atcttttttc ctgctgcaac tggtattctg gctggagcaa 1680
atatctcagg tgatcttgca gatcctcagt cagccatacc caaaggaaca ctcctagcca 1740
ttttaattac tacattggtt tacgtaggaa ttgcagtatc tgtaggttct tgtgttgttc 1800
gagatgccac tggaaacgtt aatgacacta tcgtaacaga gctaacaaac tgtacttctg 1860
cagcctgcaa attaaacttt gatttttcat cttgtgaaag cagtccttgt tcctatggcc 1920
taatgaacaa cttccaggta atgagtatgg tgtcaggatt tacaccacta atttctgcag 1980
gtatattttc agccactctt tcttcagcat tagcatccct agtgagtgct cccaaaatat 2040
ttcaggctct atgtaaggac aacatctacc cagctttcca gatgtttgct aaaggttatg 2100
ggaaaaataa tgaacctctt cgtggctaca tcttaacatt cttaattgca cttggattca 2160
tcttaattgc tgaactgaat gttattgcac caattatctc aaacttcttc cttgcatcat 2220
atgcattgat caatttttca gtattccatg catcacttgc aaaatctcca ggatggcgtc 2280
ctgcattcaa atactacaac atgtggatat cacttcttgg agcaattctt tgttgcatag 2340
taatgttcgt cattaactgg tgggctgcat tgctaacata tgtgatagtc cttgggctgt 2400
atatttatgt tacctacaaa aaaccagatg tgaattgggg atcctctaca caagccctga 2460
cttacctgaa tgcactgcag cattcaattc gtctttctgg agtggaagac cacgtgaaaa 2520
actttaggcc acagtgtctt gttatgacag gtgctccaaa ctcacgtcca gctttacttc 2580
atcttgttca tgatttcaca aaaaatgttg gtttgatgat ctgtggccat gtacatatgg 2640
gtcctcgaag acaagccatg aaagagatgt ccatcgatca agccaaatat cagcgatggc 2700
ttattaagaa caaaatgaag gcattttatg ctccagtaca tgcagatgac ttgagagaag 2760
gtgcacagta tttgatgcag gctgctggtc ttggtcgtat gaagccaaac acacttgtcc 2820
ttggatttaa gaaagattgg ttgcaagcag atatgaggga tgtggatatg tatataaact 2880
tatttcatga tgcttttgac atacaatatg gagtagtggt tattcgccta aaagaaggtc 2940
tggatatatc tcatcttcaa ggacaagaag aattattgtc atcacaagag aaatctcctg 3000
gcaccaagga tgtggtagta agtgtggaat atagtaaaaa gtccgattta gatacttcca 3060
aaccactcag tgaaaaacca attacacaca aagttgagga agaggatggc aagactgcaa 3120
ctcaaccact gttgaaaaaa gaatccaaag gccctattgt gcctttaaat gtagctgacc 3180
aaaagcttct tgaagctagt acacagtttc agaaaaaaca aggaaagaat actattgatg 3240
tctggtggct ttttgatgat ggaggtttga ccttattgat accttacctt ctgacgacca 3300
agaaaaaatg gaaagactgt aagatcagag tattcattgg tggaaagata aacagaatag 3360
accatgaccg gagagcgatg gctactttgc ttagcaagtt ccggatagac ttttctgata 3420
tcatggttct aggagatatc aataccaaac caaagaaaga aaatattata gcttttgagg 3480
aaatcattga gccatacaga cttcatgaag atgataaaga gcaagatatt gcagataaaa 3540
tgaaagaaga tgaaccatgg cgaataacag ataatgagct tgaactttat aagaccaaga 3600
cataccggca gatcaggtta aatgagttat taaaggaaca ttcaagcaca gctaatatta 3660
ttgtcatgag tctcccagtt gcacgaaaag gtgctgtgtc tagtgctctc tacatggcat 3720
ggttagaagc tctatctaag gacctaccac caatcctcct agttcgtggg aatcatcaga 3780
gtgtccttac cttctattca taaatgttct atacagtgga cagccctcca gaatggtact 3840
tcagtgccta gtgtagtaac ctgaaatctt caatgacaca ttaacatcac aatggcgaat 3900
ggtgactttt ctttcacgat ttcattaatt tgaaagcaca caggaaagct tgctccattg 3960
ataacgtgta tggagacttc ggttttagtc aattccatat ctcaatctta atggtgattc 4020
ttctctgttg aactgaagtt tgtgagagta gttttcctttgctacttgaa tagcaataaa 4080
agcgtgttaa ctttttgg 4098
<210>46
<211>3311
<212>DNA
<213>人
<400>46
tgctaatgct tttggtacaa atggatgtgg aatataattg aatattttct tgtttaaggg 60
gagcatgaag aggtgttgag gttatgtcaa gcatctggca cagctgaagg cagatggaaa 120
tatttacaag tacgcaattt gagactaaga tattgttatc attctcctat tgaagacaag 180
agcaatagta aaacacatca ggtcaggggg ttaaagacct gtgataaacc acttccgata 240
agttggaaac gtgtgtctat attttcatat ctgtatatat ataatggtaa agaaagacac 300
cttcgtaacc cgcattttcc aaagagagga atcacaggga gatgtacagc aatggggcca 360
tttaagagtt ctgtgttcat cttgattctt caccttctag aaggggccct gagtaattca 420
ctcattcagc tgaacaacaa tggctatgaa ggcattgtcg ttgcaatcga ccccaatgtg 480
ccagaagatg aaacactcat tcaacaaata aaggacatgg tgacccaggc atctctgtat 540
ctgtttgaag ctacaggaaa gcgattttat ttcaaaaatg ttgccatttt gattcctgaa 600
acatggaaga caaaggctga ctatgtgaga ccaaaacttg agacctacaa aaatgctgat 660
gttctggttg ctgagtctac tcctccaggt aatgatgaac cctacactga gcagatgggc 720
aactgtggag agaagggtga aaggatccac ctcactcctg atttcattgc aggaaaaaag 780
ttagctgaat atggaccaca aggtaaggca tttgtccatg agtgggctca tctacgatgg 840
ggagtatttg acgagtacaa taatgatgag aaattctact tatccaatgg aagaatacaa 900
gcagtaagat gttcagcagg tattactggt acaaatgtag taaagaagtg tcagggaggc 960
agctgttaca ccaaaagatg cacattcaat aaagttacag gactctatga aaaaggatgt 1020
gagtttgttc tccaatcccg ccagacggag aaggcttcta taatgtttgc acaacatgtt 1080
gattctatag ttgaattctg tacagaacaa aaccacaaca aagaagctcc aaacaagcaa 1140
aatcaaaaat gcaatctccg aagcacatgg gaagtgatcc gtgattctga ggactttaag 1200
aaaaccactc ctatgacaac acagccacca aatcccacct tctcattgct gcagattgga 1260
caaagaattg tgtgtttagt ccttgacaaa tctggaagca tggcgactgg taaccgcctc 1320
aatcgactga atcaagcagg ccagcttttc ctgctgcaga cagttgagct ggggtcctgg 1380
gttgggatgg tgacatttga cagtgctgcc catgtacaaa gtgaactcat acagataaac 1440
agtggcagtg acagggacac actcgccaaa agattacctg cagcagcttc aggagggacg 1500
tccatctgca gcgggcttcg atcggcattt actgtgatta ggaagaaata tccaactgat 1560
ggatctgaaa ttgtgctgct gacggatggg gaagacaaca ctataagtgg gtgctttaac 1620
gaggtcaaac aaagtggtgc catcatccac acagtcgctt tggggccctc tgcagctcaa 1680
gaactagagg agctgtccaa aatgacagga ggtttacaga catatgcttc agatcaagtt 1740
cagaacaatg gcctcattga tgcttttggg gccctttcat caggaaatgg agctgtctct 1800
cagcgctcca tccagcttga gagtaaggga ttaaccctcc agaacagcca gtggatgaat 1860
ggcacagtga tcgtggacag caccgtggga aaggacactt tgtttcttat cacctggaca 1920
acgcagcctc cccaaatcct tctctgggat cccagtggac agaagcaagg t~ctttgta 1980
gtggacaaaa acaccaaaat ggcctacctc caaatcccag gcattgctaa ggttggcact 2040
tggaaataca gtctgcaagc aagctcacaa accttgaccc tgactgtcac gtcccgtgcg 2100
tccaatgcta ccctgcctcc aattacagtg acttccaaaa cgaacaagga caccagcaaa 2160
ttccccagcc ctctggtagt ttatgcaaat attcgccaag gagcctcccc aattctcagg 2220
gccagtgtca cagccctgat tgaatcagtg aatggaaaaa cagttacctt ggaactactg 2280
gataatggag caggtgctga tgctactaag gatgacggtg tctactcaag gtatttcaca 2340
acttatgaca cgaatggtag atacagtgta aaagtgcggg ctctgggagg agttaacgca 2400
gccagacgga gagtgatacc ccagcagagt ggagcactgt acatacctgg ctggattgag 2460
aatgatgaaa tacaatggaa tccaccaaga cctgaaatta ataaggatga tgttcaacac 2520
aagcaagtgt gtttcagcag aacatcctcg ggaggctcat ttgtggcttc tgatgtccca 2580
aatgctccca tacctgatct cttcccacct ggccaaatca ccgacctgaa ggcggaaatt 2640
cacgggggca gtctcattaa tctgacttgg acagctcctg gggatgatta tgaccatgga 2700
acagctcaca agtatatcat tcgaataagt acaagtattc ttgatctcag agacaagttc 2760
aatgaatctc ttcaagtgaa tactactgct ctcatcccaa aggaagccaa ctctgaggaa 2820
gtctttttgt ttaaaccaga aaacattact tttgaaaatg gcacagatct tttcattgct 2880
attcaggctg ttgataaggt cgatctgaaa tcagaaatat ccaacattgc acgagtatct 2940
ttgtttattc ctccacagac tccgccagag acacctagtc ctgatgaaac gtctgctcct 3000
tgtcctaata ttcatatcaa cagcaccatt cctggcattc acattttaaa aattatgtgg 3060
aagtggatag gagaactgca gctgtcaata gcctagggct gaatttttgt cagataaata 3120
aaataaatca ttcatccttt ttttgattat aaaattttct aaaatgtatt ttagacttcc 3180
tgtagggggc gatatactaa atgtatatag tacatttata ctaaatgtat tcctgtaggg 3240
ggcgatatac taaatgtatt ttagacttcc tgtagggggc gataaaataa aatgctaaac 3300
aactgggtaa a 3311
<210>47
<211>3311
<212>DNA
<213>人
<400>47
tgctaatgct tttggtacaa atggatgtgg aatataattg aatattttct tgtttaaggg 60
gagcatgaag aggtgttgag gttatgtcaa gcatctggca cagctgaagg cagatggaaa 120
tatttacaag tacgcaattt gagactaaga tattgttatc attctcctat tgaagacaag 180
agcaatagta aaacacatca ggtcaggggg ttaaagacct gtgataaacc acttccgata 240
agttggaaac gtgtgtctat attttcatat ctgtatatat ataatggtaa agaaagacac 300
cttcgtaacc cgcattttcc aaagagagga atcacaggga gatgtacagc aatggggcca 360
tttaagagtt ctgtgttcat cttgattctt caccttctag aaggggccct gagtaattca 420
ctcattcagc tgaacaacaa tggctatgaa ggcattgtcg ttgcaatcga ccccaatgtg 480
ccagaagatg aaacactcat tcaacaaata aaggacatgg tgacccaggc atctctgtat 540
ctgtttgaag ctacaggaaa gcgattttat ttcaaaaatg ttgccatttt gattcctgaa 600
acatggaaga caaaggctga ctatgtgaga ccaaaacttg agacctacaa aaatgctgat 660
gttctggttg ctgagtctac tcctccaggt aatgatgaac cctacactga gcagatgggc 720
aactgtggag agaagggtga aaggatccac ctcactcctg atttcattgc aggaaaaaag 780
ttagctgaat atggaccaca aggtaaggca tttgtccatg agtgggctca tctacgatgg 840
ggagtatttg acgagtacaa taatgatgag aaattctact tatccaatgg aagaatacaa 900
gcagtaagat gttcagcagg tattactggt acaaatgtag taaagaagtg tcagggaggc 960
agctgttaca ccaaaagatg cacattcaat aaagttacag gactctatga aaaaggatgt 1020
gagtttgttc tccaatcccg ccagacggag aaggcttcta taatgtttgc acaacatgtt 1080
gattctatag ttgaattctg tacagaacaa aaccacaaca aagaagctcc aaacaagcaa 1140
aatcaaaaat gcaatctccg aagcacatgg gaagtgatcc gtgattctga ggactttaag 1200
aaaaccactc ctatgacaac acagccacca aatcccacct tctcattgct gcagattgga 1260
caaagaattg tgtgtttagt ccttgacaaa tctggaagca tggcgactgg taaccgcctc 1320
aatcgactga atcaagcagg ccagcttttc ctgctgcaga cagttgagct ggggtcctgg 1380
gttgggatgg tgacatttga cagtgctgcc catgtacaaa gtgaactcat acagataaac 1440
agtggcagtg acagggacac actcgccaaa agattacctg cagcagcttc aggagggacg 1500
tccatctgca gcgggcttcg atcggcattt actgtgatta ggaagaaata tccaactgat 1560
ggatctgaaa ttgtgctgct gacggatggg gaagacaaca ctataagtgg gtgctttaac 1620
gaggtcaaac aaagtggtgc catcatccac acagtcgctt tggggccctc tgcagctcaa 1680
gaactagagg agctgtccaa aatgacagga ggtttacaga catatgcttc agatcaagtt 1740
cagaacaatg gcctcattga tgcttttggg gccctttcat caggaaatgg agctgtctct 1800
cagcgctcca tccagcttga gagtaaggga ttaaccctcc agaacagcca gtggatgaat 1860
ggcacagtga tcgtggacag caccgtggga aaggacactt tgtttcttat cacctggaca 1920
acgcagcctc cccaaatcct tctctgggat cccagtggac agaagcaagg tggctttgta 1980
gtggacaaaa acaccaaaat ggcctacctc caaatcccag gcattgctaa ggttggcact 2040
tggaaataca gtctgcaagc aagctcacaa accttgaccc tgactgtcac gtcccgtgcg 2100
tccaatgcta ccctgcctcc aattacagtg acttccaaaa cgaacaagga caccagcaaa 2160
ttccccagcc ctctggtagt ttatgcaaat attcgccaag gagcctcccc aattctcagg 2220
gccagtgtca cagccctgat tgaatcagtg aatggaaaaa cagttacctt ggaactactg 2280
gataatggag caggtgctga tgctactaag gatgacggtg tctactcaag gtatttcaca 2340
acttatgaca cgaatggtag atacagtgta aaagtgcggg ctctgggagg agttaacgca 2400
gccagacgga gagtgatacc ccagcagagt ggagcactgt acatacctgg ctggattgag 2460
aatgatgaaa tacaatggaa tccaccaaga cctgaaatta ataaggatga tgttcaacac 2520
aagcaagtgt gtttcagcag aacatcctcg ggaggctcat ttgtggcttc tgatgtccca 2580
aatgctccca tacctgatct cttcccacct ggccaaatca ccgacctgaa ggcggaaatt 2640
cacgggggca gtctcattaa tctgacttgg acagctcctg gggatgatta tgaccatgga 2700
acagctcaca agtatatcat tcgaataagt acaagtattc ttgatctcag agacaagttc 2760
aatgaatctc ttcaagtgaa tactactgct ctcatcccaa aggaagccaa ctctgaggaa 2820
gtctttttgt ttaaaccaga aaacattact tttgaaaatg gcacagatct tttcattgct 2880
attcaggctg ttgataaggt cgatctgaaa tcagaaatat ccaacattgc acgagtatct 2940
ttgtttattc ctccacagac tccgccagag acacctagtc ctgatgaaac gtctgctcct 3000
tgtcctaata ttcatatcaa cagcaccatt cctggcattc acattttaaa aattatgtgg 3060
aagtggatag gagaactgca gctgtcaata gcctagggct gaatttttgt cagataaata 3120
aaataaatca ttcatccttt ttttgattat aaaattttct aaaatgtatt ttagacttcc 3180
tgtagggggc gatatactaa atgtatatag tacatttata ctaaatgtat tcctgtaggg 3240
ggcgatatac taaatgtatt ttagacttcc tgtagggggc gataaaataa aatgctaaac 3300
aactgggtaa a 3311
<210>48
<211>3697
<212>DNA
<213>人
<400>48
agggagtgtt cccgggggag atactccagt cgtagcaaga gtctcgacca ctgaatggaa 60
gaaaaggact tttaaccacc attttgtgac ttacagaaag gaatttgaat aaagaaaact 120
atgatacttc aggcccatct tcactccctg tgtcttctta tgctttattt ggcaactgga 180
tatggccaag aggggaagtt tagtggaccc ctgaaaccca tgacattttc tatttatgaa 240
ggccaagaac cgagtcaaat tatattccag tttaaggcca atcctcctgc tgtgactttt 300
gaactaactg gggagacaga caacatattt gtgatagaac gggagggact tctgtattac 360
aacagagcct tggacaggga aacaagatct actcacaatc tccaggttgc agccctggac 420
gctaatggaa ttatagtgga gggtccagtc cctatcacca tagaagtgaa ggacatcaac 480
gacaatcgac ccacgtttct ccagtcaaag tacgaaggct cagtaaggca gaactctcgc 540
ccaggaaagc ccttcttgta tgtcaatgcc acagacctgg atgatccggc cactcccaat 600
ggccagcttt attaccagat tgtcatccag cttcccatga tcaacaatgt catgtacttt 660
cagatcaaca acaaaacggg agccatctct cttacccgag agggatctca ggaattgaat 720
cctgctaaga atccttccta taatctggtg atctcagtga aggacatggg aggccagagt 780
gagaattcct tcagtgatac cacatctgtg gatatcatag tgacagagaa tatttggaaa 840
gcaccaaaac ctgtggagat ggtggaaaac tcaactgatc ctcaccccat caaaatcact 900
caggtgcggt ggaatgatcc cggtgcacaa tattccttag ttgacaaaga gaagctgcca 960
agattcccat tttcaattga ccaggaagga gatatttacg tgactcagcc cttggaccga 1020
gaagaaaagg atgcatatgt tttttatgca gttgcaaagg atgagtacgg aaaaccactt 1080
tcatatccgc tggaaattca tgtaaaagtt aaagatatta atgataatcc acctacatgt 1140
ccgtcaccag taaccgtatt tgaggtccag gagaatgaac gactgggtaa cagtatcggg 1200
acccttactg cacatgacag ggatgaagaa aatactgcca acagttttct aaactacagg 1260
attgtggagc aaactcccaa acttcccatg gatggactct tcctaatcca aacctatgct 1320
ggaatgttac agttagctaa acagtccttg aagaagcaag atactcctca gtacaactta 1380
acgatagagg tgtctgacaa agatttcaag accctttgtt ttgtgcaaat caacgttatt 1440
gatatcaatg atcagatccc catctttgaa aaatcagatt atggaaacct gactcttgct 1500
gaagacacaa acattgggtc caccatctta accatccagg ccactgatgc tgatgagcca 1560
tttactggga gttctaaaat tctgtatcat atcataaagg gagacagtga gggacgcctg 1620
ggggttgaca cagatcccca taccaacacc ggatatgtca taattaaaaa gcctcttgat 1680
tttgaaacag cagctgtttc caacattgtg ttcaaagcag aaaatcctga gcctctagtg 1740
tttggtgtga agtacaatgc aagttctttt gccaagttca cgcttattgt gacagatgtg 1800
aatgaagcac ctcaattttc ccaacacgta ttccaagcga aagtcagtga ggatgtagct 1860
ataggcacta aagtgggcaa tgtgactgcc aaggatccag aaggtctgga cataagctat 1920
tcactgaggg gagacacaag aggttggctt aaaattgacc acgtgactgg tgagatcttt 1980
agtgtggctc cattggacag agaagccgga agtccatatc gggtacaagt ggtggccaca 2040
gaagtagggg ggtcttcctt gagctctgtg tcagagttcc acctgatcct tatggatgtg 2100
aatgacaacc ctcccaggct agccaaggac tacacgggct tgttcttctg ccatcccctc 2160
agtgcacctg gaagtctcat tttcgaggct actgatgatg atcagcactt atttcggggt 2220
ccccatttta cattttccct cggcagtgga agcttacaaa acgactggga agtttccaaa 2280
atcaatggta ctcatgcccg actgtctacc aggcacacag agtttgagga gagggagtat 2340
gtcgtcttga tccgcatcaa tgatgggggt cggccaccct tggaaggcat tgtttcttta 2400
ccagttacat tctgcagttg tgtggaagga agttgtttcc ggccagcagg tcaccagact 2460
gggataccca ctgtgggcat ggcagttggt atactgctga ccacccttct ggtgattggt 2520
ataattttag cagttgtgtt tatccgcata aagaaggata aaggcaaaga taatgttgaa 2580
agtgctcaag catctgaagt caaacctctg agaagctgaa tttgaaaagg aatgtttgaa 2640
tttatatagc aagtgctatt tcagcaacaa ccatctcatc ctattacttt tcatctaacg 2700
tgcattataa ttttttaaac agatattccc tcttgtcctt taatatttgc taaatatttc 2760
ttttttgagg tggagtcttg ctctgtcgcc caggctggag tacagtggtg tgatcccagc 2820
tcactgcaac ctccgcctcc tgggttcaca tgattctcct gcctcagctt cctaagtagc 2880
tgggtttaca ggcacccacc accatgccca gctaattttt gtatttttaa tagagacggg 2940
gtttcgccat ttggccaggc tggtcttgaa ctcctgacgt caagtgatct gcctgccttg 3000
gtctcccaat acaggcatga accactgcac ccacctactt agatatttca tgtgctatag 3060
acattagaga gatttttcat ttttccatga catttttcct ctctgcaaat ggcttagcta 3120
cttgtgtttt tcccttttgg ggcaagacag actcattaaa tattctgtac attttttctt 3180
tatcaaggag atatatcagt gttgtctcat agaactgcct ggattccatt tatgtttttt 3240
ctgattccat cctgtgtccc cttcatcctt gactcctttg gtatttcact gaatttcaaa 3300
catttgtcag agaagaaaaa cgtgaggact caggaaaaat aaataaataa aagaacagcc 3360
ttttccctta gtattaacag aaatgtttct gtgtcattaa ccatctttaa tcaatgtgac 3420
atgttgctct ttggctgaaa ttcttcaact tggaaatgac acagacccac agaaggtgtt 3480
caaacacaac ctactctgca aaccttggta aaggaaccag tcagctggcc agatttcctc 3540
actacctgcc atgcatacat gctgcgcatg ttttcttcat tcgtatgtta gtaaagtttt 3600
ggttattata tatttaacat gtggaagaaa acaagacatg aaaagagtgg tgacaaatca 3660
agaataaaca ctggttgtag tcagttttgt ttgttaa 3697
<210>49
<211>3697
<212>DNA
<213>人
<400>49
agggagtgtt cccgggggag atactccagt cgtagcaaga gtctcgacca ctgaatggaa 60
gaaaaggact tttaaccacc attttgtgac ttacagaaag gaatttgaat aaagaaaact 120
atgatacttc aggcccatct tcactccctg tgtcttctta tgctttattt ggcaactgga 180
tatggccaag aggggaagtt tagtggaccc ctgaaaccca tgacattttc tatttatgaa 240
ggccaagaac cgagtcaaat tatattccag tttaaggcca atcctcctgc tgtgactttt 300
gaactaactg gggagacaga caacatattt gtgatagaac gggagggact tctgtattac 360
aacagagcct tggacaggga aacaagatct actcacaatc tccaggttgc agccctggac 420
gctaatggaa ttatagtgga gggtccagtc cctatcacca tagaagtgaa ggacatcaac 480
gacaatcgac ccacgtttct ccagtcaaag tacgaaggct cagtaaggca gaactctcgc 540
ccaggaaagc ccttcttgta tgtcaatgcc acagacctgg atgatccggc cactcccaat 600
ggccagcttt attaccagat tgtcatccag cttcccatga tcaacaatgt catgtacttt 660
cagatcaaca acaaaacggg agccatctct cttacccgag agggatctca ggaattgaat 720
cctgctaaga atccttccta taatctggtg atctcagtga aggacatggg aggccagagt 780
gagaattcct tcagtgatac cacatctgtg gatatcatag tgacagagaa tatttggaaa 840
gcaccaaaac ctgtggagat ggtggaaaac tcaactgatc ctcaccccat caaaatcact 900
caggtgcggt ggaatgatcc cggtgcacaa tattccttag ttgacaaaga gaagctgcca 960
agattcccat tttcaattga ccaggaagga gatatttacg tgactcagcc cttggaccga 1020
gaagaaaagg atgcatatgt tttttatgca gttgcaaagg atgagtacgg aaaaccactt 1080
tcatatccgc tggaaattca tgtaaaagtt aaagatatta atgataatcc acctacatgt 1140
ccgtcaccag taaccgtatt tgaggtccag gagaatgaac gactgggtaa cagtatcggg 1200
acccttactg cacatgacag ggatgaagaa aatactgcca acagttttct aaactacagg 1260
attgtggagc aaactcccaa acttcccatg gatggactct tcctaatcca aacctatgct 1320
ggaatgttac agttagctaa acagtccttg aagaagcaag atactcctca gtacaactta 1380
acgatagagg tgtctgacaa agatttcaag accctttgtt ttgtgcaaat caacgttatt 1440
gatatcaatg atcagatccc catctttgaa aaatcagatt atggaaacct gactcttgct 1500
gaagacacaa acattgggtc caccatctta accatccagg ccactgatgc tgatgagcca 1560
tttactggga gttctaaaat tctgtatcat atcataaagg gagacagtga gggacgcctg 1620
ggggttgaca cagatcccca taccaacacc ggatatgtca taattaaaaa gcctcttgat 1680
tttgaaacag cagctgtttc caacattgtg ttcaaagcag aaaatcctga gcctctagtg 1740
tttggtgtga agtacaatgc aagttctttt gccaagttca cgcttattgt gacagatgtg 1800
aatgaagcac ctcaattttc ccaacacgta ttccaagcga aagtcagtga ggatgtagct 1860
ataggcacta aagtgggcaa tgtgactgcc aaggatccag aaggtctgga cataagctat 1920
tcactgaggg gagacacaag aggttggctt aaaattgacc acgtgactgg tgagatcttt 1980
agtgtggctc cattggacag agaagccgga agtccatatc gggtacaagt ggtggccaca 2040
gaagtagggg ggtcttcctt gagctctgtg tcagagttcc acctgatcct tatggatgtg 2100
aatgacaacc ctcccaggct agccaaggac tacacgggct tgttcttctg ccatcccctc 2160
agtgcacctg gaagtctcat tttcgaggct actgatgatg atcagcactt atttcggggt 2220
ccccatttta cattttccct cggcagtgga agcttacaaa acgactggga agtttccaaa 2280
atcaatggta ctcatgcccg actgtctacc aggcacacag agtttgagga gagggagtat 2340
gtcgtcttga tccgcatcaa tgatgggggt cggccaccct tggaaggcat tgtttcttta 2400
ccagttacat tctgcagttg tgtggaagga agttgtttcc ggccagcagg tcaccagact 2460
gggataccca ctgtgggcat ggcagttggt atactgctga ccacccttct ggtgattggt 2520
ataattttag cagttgtgtt tatccgcata aagaaggata aaggcaaaga taatgttgaa 2580
agtgctcaag catctgaagt caaacctctg agaagctgaa tttgaaaagg aatgtttgaa 2640
tttatatagc aagtgctatt tcagcaacaa ccatctcatc ctattacttt tcatctaacg 2700
tgcattataa ttttttaaac agatattccc tcttgtcctt taatatttgc taaatatttc 2760
ttttttgagg tggagtcttg ctctgtcgcc caggctggag tacagtggtg tgatcccagc 2820
tcactgcaac ctccgcctcc tgggttcaca tgattctcct gcctcagctt cctaagtagc 2880
tgggtttaca ggcacccacc accatgccca gctaattttt gtatttttaa tagagacggg 2940
gtttcgccat ttggccaggc tggtcttgaa ctcctgacgt caagtgatct gcctgccttg 3000
gtctcccaat acaggcatga accactgcac ccacctactt agatatttca tgtgctatag 3060
acattagaga gatttttcat ttttccatga catttttcct ctctgcaaat ggcttagcta 3120
cttgtgtttt tcccttttgg ggcaagacag actcattaaa tattctgtac attttttctt 3180
tatcaaggag atatatcagt gttgtctcat agaactgcct ggattccatt tatgtttttt 3240
ctgattccat cctgtgtccc cttcatcctt gactcctttg gtatttcact gaatttcaaa 3300
catttgtcag agaagaaaaa cgtgaggact caggaaaaat aaataaataa aagaacagcc 3360
ttttccctta gtattaacag aaatgtttct gtgtcattaa ccatctttaa tcaatgtgac 3420
atgttgctct ttggctgaaa ttcttcaact tggaaatgac acagacccac agaaggtgtt 3480
caaacacaac ctactctgca aaccttggta aaggaaccag tcagctggcc agatttcctc 3540
actacctgcc atgcatacat gctgcgcatg ttttcttcat tcgtatgtta gtaaagtttt 3600
ggttattata tatttaacat gtggaagaaa acaagacatg aaaagagtgg tgacaaatca 3660
agaataaaca ctggttgtag tcagttttgt ttgttaa 3697
<210>50
<211>3803
<212>DNA
<213>人
<400>50
ccatggtagg agcgctcgcc tcgctgcggt gcccgctgag gccatgccgg ggccccggcg 60
ccccgctggc tcccgcctgc gcctgctcct gctcctgctg ctgccgccgc tgctgctgct 120
gctccggggc agccacgcgg gcaacctgac ggtagccgtg gtactgccgc tggccaatac 180
ctcgtacccc tggtcgtggg cgcgcgtggg acccgccgtg gagctggccc tggcccaggt 240
gaaggcgcgc cccgacttgc tgccgggctg gacggtccgc acggtgctgg gcagcagcga 300
aaacgcgctg ggcgtctgct ccgacaccgc agcgcccctg gccgcggtgg acctcaagtg 360
ggagcacaac cccgctgtgt tcctgggccc cggctgcgtg tacgccgccg ccccagtggg 420
gcgcttcacc gcgcactggc gggtcccgct gctgaccgcc ggcgccccgg cgctgggctt 480
cggtgtcaag gacgagtatg cgctgaccac ccgcgcgggg cccagctacg ccaagctggg 540
ggacttcgtg gcggcgctgc accgacggct gggctgggag cgccaagcgc tcatgctcta 600
cgcctaccgg ccgggtgacg aagagcactg cttcttcctc gtggaggggc tgttcatgcg 660
ggtccgcgac cgcctcaata ttacggtgga ccacctggag ttcgccgagg acgacctcag 720
ccactacacc aggctgctgc ggaccatgcc gcgcaaaggc cgagttatct acatctgcag 780
ctcccctgat gccttcagaa ccctcatgct cctggccctg gaagctggct tgtgtgggga 840
ggactacgtt ttcttccacc tggatatctt tgggcaaagc ctgcaaggtg gacagggccc 900
tgctccccgc aggccctggg agagagggga tgggcaggat gtcagtgccc gccaggcctt 960
tcaggctgcc aaaatcatta catataaaga cccagataat cccgagtact tggaattcct 1020
gaagcagtta aaacacctgg cctatgagca gttcaacttc accatggagg atggcctggt 1080
gaacaccatc ccagcatcct tccacgacgg gctcctgctc tatatccagg cagtgacgga 1140
gactctggca catgggggaa ctgttactga tggggagaac atcactcagc ggatgtggaa 1200
ccgaagcttt caaggtgtga caggatacct gaaaattgat agcagtggcg atcgggaaac 1260
agacttctcc ctctgggata tggatcccga gaatggtgcc ttcagggttg tactgaacta 1320
caatgggact tcccaagagc tggtggctgt gtcggggcgc aaactgaact ggcccctggg 1380
gtaccctcct cctgacatcc ccaaatgtgg ctttgacaac gaagacccag catgcaacca 1440
agatcacctt tccaccctgg aggtgctggc tttggtgggc agcctctcct tgctcggcat 1500
tctgattgtc tccttcttca tatacaggaa gatgcagctg gagaaggaac tggcctcgga 1560
gctgtggcgg gtgcgctggg aggacgttga gcccagtagc cttgagaggc acctgcggag 1620
tgcaggcagc cggctgaccc tgagcgggag aggctccaat tacggctccc tgctaaccac 1680
agagggccag ttccaagtct ttgccaagac agcatattat aagggcaacc tcgtggctgt 1740
gaaacgtgtg aaccgtaaac gcattgagct gacacgaaaa gtcctgtttg aactgaagca 1800
tatgcgggat gtgcagaatg aacacctgac caggtttgtg ggagcctgca ccgacccccc 1860
caatatctgc atcctcacag agtactgtcc ccgtgggagc ctgcaggaca ttctggagaa 1920
tgagagcatc accctggact ggatgttccg gtactcactc accaatgaca tcgtcaaggg 1980
catgctgttt ctacacaatg gggctatctg ttcccatggg aacctcaagt catccaactg 2040
cgtggtagat gggcgctttg tgctcaagat caccgactat gggctggaga gcttcaggga 2100
cctggaccca gagcaaggac acaccgttta tgccaaaaag ctgtggacgg cccctgagct 2160
cctgcgaatg gcttcacccc ctgtgcgggg ctcccaggct ggtgacgtat acagctttgg 2220
gatcatcctt caggagattg ccctgaggag tggggtcttc cacgtggaag gtttggacct 2280
gagccccaaa gagatcatcg agcgggtgac tcggggtgag cagcccccct tccggccctc 2340
cctggccctg cagagtcacc tggaggagtt ggggctgctc atgcagcggt gctgggctga 2400
ggacccacag gagaggccac cattccagca gatccgcctg acgttgcgca aatttaacag 2460
ggagaacagc agcaacatcc tggacaacct gctgtcccgc atggagcagt acgcgaacaa 2520
tctggaggaa ctggtggagg agcggaccca ggcatacctg gaggagaagc gcaaggctga 2580
ggccctgctc taccagatcc tgcctcactc agtggctgag cagctgaagc gtggggagac 2640
ggtgcaggcc gaagcctttg acagtgttac catctacttc agtgacattg tgggtttcac 2700
agcgctgtcg gcggagagca cacccatgca ggtggtgacc ctgctcaatg acctgtacac 2760
ttgctttgat gctgtcatag acaactttga tgtgtacaag gtggagacaa ttggcgatgc 2820
ctacatggtg gtgtcagggc tccctgtgcg gaacgggcgg ctacacgcct gcgaggtagc 2880
ccgcatggcc ctggcactgc tggatgctgt gcgctccttc cgaatccgcc accggcccca 2940
ggagcagctg cgcttgcgca ttggcatcca cacaggacct gtgtgtgctg gagtggtggg 3000
actgaagatg ccccgttact gtctctttgg ggatacagtc aacacagcct caagaatgga 3060
gtctaatggg gaagccctga agatccactt gtcttctgag accaaggctg tcctggagga 3120
gtttggtggt ttcgagctgg agcttcgagg ggatgtagaa atgaagggca aaggcaaggt 3180
tcggacctac tggctccttg gggagagggg gagtagcacc cgaggctgac ctgcctcctc 3240
tcctatccct ccacacctcc cctaccctgt gccagaagca acagaggtgc caggcctcag 3300
cctcacccac agcagcccca tcgccaaagg atggaagtaa tttgaatagc tcaggtgtgc 3360
tgaccccagt gaagacacca gataggacct ctgagagggg actggcatgg ggggatctca 3420
gagcttacag gctgagccaa gcccacggcc atgcacaggg acactcacac aggcacacgc 3480
acctgctctc cacctggact caggccgggc tgggctgtgg atccttgatc ccctcccctc 3540
cccatgctct cctccctcag ccttgctacc ctgtgactta ctgggaggag agtcacctga 3600
aggggaacat gaaaagagac taggtgaaga gagggcaggg gagcccacat ctggggctgg 3660
cccacaatac ctgctccccc gaccccctcc acccagcagt agacacagtg cacaggggag 3720
aagaggggtg gcgcagaagg gttgggggcc tgtatgcctt gcttctacca tgagcagaga 3780
caattaaaat ctttattcca gtg 3803
<210>51
<211>3803
<212>DNA
<213>人
<400>51
ccatggtagg agcgctcgcc tcgctgcggt gcccgctgag gccatgccgg ggccccggcg 60
ccccgctggc tcccgcctgc gcctgctcct gctcctgctg ctgccgccgc tgctgctgct 120
gctccggggc agccacgcgg gcaacctgac ggtagccgtg gtactgccgc tggccaatac 180
ctcgtacccc tggtcgtggg cgcgcgtggg acccgccgtg gagctggccc tggcccaggt 240
gaaggcgcgc cccgacttgc tgccgggctg gacggtccgc acggtgctgg gcagcagcga 300
aaacgcgctg ggcgtctgct ccgacaccgc agcgcccctg gccgcggtgg acctcaagtg 360
ggagcacaac cccgctgtgt tcctgggccc cggctgcgtg tacgccgccg ccccagtggg 420
gcgcttcacc gcgcactggc gggtcccgct gctgaccgcc ggcgccccgg cgctgggctt 480
cggtgtcaag gacgagtatg cgctgaccac ccgcgcgggg cccagctacg ccaagctggg 540
ggacttcgtg gcggcgctgc accgacggct gggctgggag cgccaagcgc tcatgctcta 600
cgcctaccgg ccgggtgacg aagagcactg cttcttcctc gtggaggggc tgttcatgcg 660
ggtccgcgac cgcctcaata ttacggtgga ccacctggag ttcgccgagg acgacctcag 720
ccactacacc aggctgctgc ggaccatgcc gcgcaaaggc cgagttatct acatctgcag 780
ctcccctgat gccttcagaa ccctcatgct cctggccctg gaagctggct tgtgtgggga 840
ggactacgtt ttcttccacc tggatatctt tgggcaaagc ctgcaaggtg gacagggccc 900
tgctccccgc aggccctggg agagagggga tgggcaggat gtcagtgccc gccaggcctt 960
tcaggctgcc aaaatcatta catataaaga cccagataat cccgagtact tggaattcct 1020
gaagcagtta aaacacctgg cctatgagca gttcaacttc accatggagg atggcctggt 1080
gaacaccatc ccagcatcct tccacgacgg gctcctgctc tatatccagg cagtgacgga 1140
gactctggca catgggggaa ctgttactga tggggagaac atcactcagc ggatgtggaa 1200
ccgaagcttt caaggtgtga caggatacct gaaaattgat agcagtggcg atcgggaaac 1260
agacttctcc ctctgggata tggatcccga gaatggtgcc ttcagggttg tactgaacta 1320
caatgggact tcccaagagc tggtggctgt gtcggggcgc aaactgaact ggcccctggg 1380
gtaccctcct cctgacatcc ccaaatgtgg ctttgacaac gaagacccag catgcaacca 1440
agatcacctt tccaccctgg aggtgctggc tttggtgggc agcctctcct tgctcggcat 1500
tctgattgtc tccttcttca tatacaggaa gatgcagctg gagaaggaac tggcctcgga 1560
gctgtggcgg gtgcgctggg aggacgttga gcccagtagc cttgagaggc acctgcggag 1620
tgcaggcagc cggctgaccc tgagcgggag aggctccaat tacggctccc tgctaaccac 1680
agagggccag ttccaagtct ttgccaagac agcatattat aagggcaacc tcgtggctgt 1740
gaaacgtgtg aaccgtaaac gcattgagct gacacgaaaa gtcctgtttg aactgaagca 1800
tatgcgggat gtgcagaatg aacacctgac caggtttgtg ggagcctgca ccgacccccc 1860
caatatctgc atcctcacag agtactgtcc ccgtgggagc ctgcaggaca ttctggagaa 1920
tgagagcatc accctggact ggatgttccg gtactcactc accaatgaca tcgtcaaggg 1980
catgctgttt ctacacaatg gggctatctg ttcccatggg aacctcaagt catccaactg 2040
cgtggtagat gggcgctttg tgctcaagat caccgactat gggctggaga gcttcaggga 2100
cctggaccca gagcaaggac acaccgttta tgccaaaaag ctgtggacgg cccctgagct 2160
cctgcgaatg gcttcacccc ctgtgcgggg ctcccaggct ggtgacgtat acagctttgg 2220
gatcatcctt caggagattg ccctgaggag tggggtcttc cacgtggaag gtttggacct 2280
gagccccaaa gagatcatcg agcgggtgac tcggggtgag cagcccccct tccggccctc 2340
cctggccctg cagagtcacc tggaggagtt ggggctgctc atgcagcggt gctgggctga 2400
ggacccacag gagaggccac cattccagca gatccgcctg acgttgcgca aatttaacag 2460
ggagaacagc agcaacatcc tggacaacct gctgtcccgc atggagcagt acgcgaacaa 2520
tctggaggaa ctggtggagg agcggaccca ggcatacctg gaggagaagc gcaaggctga 2580
ggccctgctc taccagatcc tgcctcactc agtggctgag cagctgaagc gtggggagac 2640
ggtgcaggcc gaagcctttg acagtgttac catctacttc agtgacattg tgggtttcac 2700
agcgctgtcg gcggagagca cacccatgca ggtggtgacc ctgctcaatg acctgtacac 2760
ttgctttgat gctgtcatag acaactttga tgtgtacaag gtggagacaa ttggcgatgc 2820
ctacatggtg gtgtcagggc tccctgtgcg gaacgggcgg ctacacgcct gcgaggtagc 2880
ccgcatggcc ctggcactgc tggatgctgt gcgctccttc cgaatccgcc accggcccca 2940
ggagcagctg cgcttgcgca ttggcatcca cacaggacct gtgtgtgctg gagtggtggg 3000
actgaagatg ccccgttact gtctctttgg ggatacagtc aacacagcct caagaatgga 3060
gtctaatggg gaagccctga agatccactt gtcttctgag accaaggctg tcctggagga 3120
gtttggtggt ttcgagctgg agcttcgagg ggatgtagaa atgaagggca aaggcaaggt 3180
tcggacctac tggctccttg gggagagggg gagtagcacc cgaggctgac ctgcctcctc 3240
tcctatccct ccacacctcc cctaccctgt gccagaagca acagaggtgc caggcctcag 3300
cctcacccac agcagcccca tcgccaaagg atggaagtaa tttgaatagc tcaggtgtgc 3360
tgaccccagt gaagacacca gataggacct ctgagagggg actggcatgg ggggatctca 3420
gagcttacag gctgagccaa gcccacggcc atgcacaggg acactcacac aggcacacgc 3480
acctgctctc cacctggact caggccgggc tgggctgtgg atccttgatc ccctcccctc 3540
cccatgctct cctccctcag ccttgctacc ctgtgactta ctgggaggag agtcacctga 3600
aggggaacat gaaaagagac taggtgaaga gagggcaggg gagcccacat ctggggctgg 3660
cccacaatac ctgctccccc gaccccctcc acccagcagt agacacagtg cacaggggag 3720
aagaggggtg gcgcagaagg gttgggggcc tgtatgcctt gcttctacca tgagcagaga 3780
caattaaaat ctttattcca gtg 3803
<210>52
<211>1155
<212>DNA
<213>人
<400>52
atggattgca gtaacggatc ggcagagtgt accggagaag gaggatcaaa agaggtggtg 60
gggactttta aggctaaaga cctaatagtc acaccagcta ccattttaaa ggaaaaacca 120
gaccccaata atctggtttt tggaactgtg ttcacggatc atatgctgac ggtggagtgg 180
tcctcagagt ttggatggga gaaacctcat atcaagcctc ttcagaacct gtcattgcac 240
cctggctcat cagctttgca ctatgcagtg gaattatttg aaggattgaa ggcatttcga 300
ggagtagata ataaaattcg actgtttcag ccaaacctca acatggatag aatgtatcgc 360
tctgctgtga gggcaactct gccggtattt gacaaagaag agctcttaga gtgtattcaa 420
cagcttgtga aattggatca agaatgggtc ccatattcaa catctgctag tctgtatatt 480
cgtcctgcat tcattggaac tgagccttct cttggagtca agaagcctac caaagccctg 540
ctctttgtac tcttgagccc agtgggacct tatttttcaa gtggaacctt taatccagtg 600
tccctgtggg ccaatcccaa gtatgtaaga gcctggaaag gtggaactgg ggactgcaag 660
atgggaggga attacggctc atctcttttt gcccaatgtg aagacgtaga taatgggtgt 720
cagcaggtcc tgtggctcta tggcagagac catcagatca ctgaagtggg aactatgaat 780
ctttttcttt actggataaa tgaagatgga gaagaagaac tggcaactcc tccactagat 840
ggcatcattc ttccaggagt gacaaggcgg tgcattctgg acctggcaca tcagtggggt 900
gaatttaagg tgtcagagag atacctcacc atggatgact tgacaacagc cctggagggg 960
aacagagtga gagagatgtt tagctctggt acagcctgtg ttgtttgccc agtttctgat 1020
atactgtaca aaggcgagac aatacacatt ccaactatgg agaatggtcc taagctggca 1080
agccgcatct tgagcaaatt aactgatatc cagtatggaa gagaagagag cgactggaca 1140
attgtgctat cctga 1155
<210>53
<211>2511
<212>DNA
<213>人
<400>53
cttttcacac tggccttaaa gaggatatat tagaagttga agtaggaagg gagccagaga 60
ggccgatggc gcaaaggtac gacgatctac cccattacgg gggcatggat ggagtaggca 120
tcccctccac gatgtatggg gacccgcatg cagccaggtc catgcagccg gtccaccacc 180
tgaaccacgg gcctcctctg cactcgcatc agtacccgca cacagctcat accaacgcca 240
tggcccccag catgggctcc tctgtcaatg acgctttaaa gagagataaa gatgccattt 300
atggacaccc cctcttccct ctcttagcac tgatttttga gaaatgtgaa ttagctactt 360
gtaccccccg cgagccgggg gtggcgggcg gggacgtctg ctcgtcagag tcattcaatg 420
aagatatagc cgtgttcgcc aaacagattc gcgcagaaaa acctctattt tcttctaatc 480
cagaactgga taacttgatg attcaagcca tacaagtatt aaggtttcat ctattggaat 540
tagagaaggt acacgaatta tgtgacaatt tctgccaccg gtatattagc tgtttgaaag 600
ggaaaatgcc tatcgatttg gtgatagacg atagagaagg aggatcaaaa tcagacagtg 660
aagatataac aagatcagca aatctaactg accagccctc ttggaacaga gatcatgatg 720
acacggcatc tactcgttca ggaggaaccc caggcccttc cagcggtggc cacacgtcac 780
acagtgggga caacagcagt gagcaaggtg atggcttgga caacagtgta gcttccccca 840
gcacaggtga cgatgatgac cctgataagg acaaaaagcg tcacaaaaag cgtggcatct 900
ttcccaaagt agccacaaat atcatgaggg cgtggctgtt ccagcatcta acacaccctt 960
acccttctga agaacagaaa aagcagttgg cacaagacac gggactcacc atccttcaag 1020
tgaacaattg gtttattaat gcccggagaa gaatagtgca gcccatgata gaccagtcca 1080
accgagcagt aagtcaagga acaccttata atcctgatgg acagcccatg ggaggtttcg 1140
taatggacgg tcagcaacat atgggaatta gagcaccagg acctatgagt ggaatgggca 1200
tgaatatggg catggagggg cagtggcact acatgtaacc ttcatctagt taaccaatcg 1260
caaagcaagg gggaaggctg caaagtatgc caggggagta tgtagcccgg ggtggtccaa 1320
tgggtgtgag tatgggacag ccaagttata cccaacccca gatgcccccc catcctgctc 1380
agctgcgtca tgggcccccc atgcatacgt acattcctgg acaccctcac cacccaacag 1440
tgatgatgca tggaggaccg ccccaccctg gaatgccaat gtcagcatca agccccacag 1500
ttcttaatac aggagaccca acaatgagtg gacaagtcat ggacattcat gctcagtagc 1560
ttaagggaat atgcattgtc tgcaatggtg actgatttca aatcatgttt tttctgcaat 1620
gactgtggag ttccattctt ggcatctact ctggaccaag gagcatccct aattcttcat 1680
agggaccttt aaaaagcagg aaataccaac tgaagtcaat ttgggggaca tgctaaataa 1740
ctatataaga cattaagaga acaaagagtg aaatattgta aatgctatta tactgttatc 1800
catattacgt tgtttcttat agatttttta aaaaaaatgt gaaatttttc cacactatgt 1860
gtgttgtttc catagctctt cacttcctcc agaagcctcc ttacattaaa aagccttaca 1920
gttatcctgc aagggacagg aaggtctgat ttgcaggatt tttagagcat taaaataact 1980
atcaggcaga agaatctttc ttctcgccta ggatttcagc catgcgcgcg ctctctctct 2040
ttctctctct tttcctctct ctccctcttt ctagcctggg gcttgaattt gcatgtctaa 2100
ttcatttact caccatattt gaattggcct gaacagatgt aaatcgggaa ggatgggaaa 2160
aactgcagtc atcaacaatg attaatcagc tgttgcaggc agtgtcttaa ggagactggt 2220
aggaggaggc atggaaacca aaaggccgtg tgtttagaag cctaattgtc acatcaagca 2280
tcattgtccc catgcaacaa ccaccacctt atacatcact tcctgtttta agcagctcta 2340
aaacatagac tgaagattta tttttaatat gttgacttta tttctgagca aagcatcggt 2400
catgtgtgta ttttttcata gtcccacctt ggagcattta tgtagacatt gtaaataaat 2460
tttgtgcaaa aaggactgga aaaatgaact gtattattgc aatttttttt t 2511
<210>54
<211>1887
<212>DNA
<213>人
<400>54
tcgcccaatt ccgggctcag acactgggct cccagctggg gactgctcca tggccatgga 60
gatagacagc aggcctgggg ggctccccgg cagtagctgc aacctaggtg cagcccgaga 120
acacatgcag gcggtcaccc gaaactacat cacccacccc cgtgtcacct acaggactgt 180
gtgcagcgtg aacgggcccc tggtggtgct ggaccgggtc aagtttgccc agtatgcgga 240
gatcgtccac ttcaccctcc cagatgggac tcagaggagc gggcaggtgc ttgaggtggc 300
tggcaccaag gcgattgttc aggtgtttga agggacatca gggatcgatg ccaggaagac 360
cacttgcgaa tttacagggg acatcctacg aactccggtg tcagaggaca tgctgggtcg 420
ggttttcaat ggctccggca agcccattga caaggggcca gtggtcatgg cggaggactt 480
tctggatatc aatggccagc ccatcaaccc gcactcccgc atctaccccg aggagatgat 540
tcagacgggc atttctccta ttgacgtcat gaacagcatt gcccgcggcc agaagatccc 600
catcttctca gcagccgggc tcccccacaa tgagattgcc gctcagatct gccgccaggc 660
ggggctggtg aagaagtcca aggctgtgct ggattaccat gacgacaact tcgccatcgt 720
ctttgcagcc atgggggtga acatggagac agccagattc ttcaagtctg actttgagca 780
gaatggaacc atggggaacg tctgcctctt cctgaacttg gccaatgacc ccacgatcga 840
gcggatcatc accccgcgcc tggcgctgac cactgctgaa ttccttgcct accagtgtga 900
gaagcatgtg ctggtcatac tgacggacat gagttcctat gcagaggcct tgcgggaggt 960
ctctgctgct agagaggagg tgcctgggcg ccgagggttt cctggatata tgtacacaga 1020
cctggccacc atctacgagc gggcgggccg tgtggagggt cggggaggat ccatcacaca 1080
gatccccatc ctcaccatgc ccaacgacga tatcacccac cctatcccag acttgacggg 1140
cttcatcaca gagggacaga tctacgtgga cagacagctt cacaacagac agatctaccc 1200
ccccatcaac gtgctccctt ccctgtcgcg gctgatgaag tcagccattg gggaaggcat 1260
gacaagaaag gaccatggag atgtctccaa ccagctgtac gcctgctatg ccatcgggaa 1320
ggacgtgcag gccatgaagg cagtagttgg ggaggaggcg ctcacctctg aggacctgct 1380
ctacctggaa ttcctgcaga agtttgagaa gaacttcatc aatcagggcc cctacgagaa 1440
ccgctcgatg ttcgagtcgc tggaccttag ctggaagctg ctgcgcatct tccccaagga 1500
gatgctgaag cgcattccgc aggccgtgat cgacgagttc tattcccgcg aggggcggct 1560
gcaggacctc gcgcctgaca ctgcgctcta gccccgcgcg ccgtggcacc ccaacaccgg 1620
caggaaccta ccctcggctc ccgggtctcc ccgtccctcg ccacccctaa ccagcggctt 1680
tcgcgccgcc ctccgccctc cgtggctccg aggtggtggg gggcgccgca gtcatccctt 1740
tcctcgctcg attccttttc ccgcgctcca tgcctccccc tcagctcccg gtgctgcgga 1800
agaactgaag gttcatgcct actctgacgg gagcatctgt attttttatg ttaaaagccc 1860
acaaaataaa aataaaaatg aactgag 1887
<210>55
<211>1506
<212>DNA
<213>人
<400>55
aggcggacaa agcccgattg ttcctgggcc ctttccccat cgcgcctggg cctgctcccc 60
agcccggggc aggggcgggg gccagtgtgg tgacacacgc tgtagctgtc tccccggctg 120
gctggctcgc tctctcctgg ggacacagag gtcggcaggc agcacacaga gggacctacg 180
ggcagctgtt ccttcccccg actcaagaat ccccggaggc ccggaggcct gcagcaggag 240
cggccatgaa gaagctgatg gtggtgctga gtctgattgc tgcagcctgg gcagaggagc 300
agaataagtt ggtgcatggc ggaccctgcg acaagacatc tcacccctac caagctgccc 360
tctacacctc gggccacttg ctctgtggtg gggtccttat ccatccactg tgggtcctca 420
cagctgccca ctgcaaaaaa ccgaatcttc aggtcttcct ggggaagcat aaccttcggc 480
aaagggagag ttcccaggag cagagttctg ttgtccgggc tgtgatccac cctgactatg 540
atgccgccag ccatgaccag gacatcatgc tgttgcgcct ggcacgccca gccaaactct 600
ctgaactcat ccagcccctt cccctggaga gggactgctc agccaacacc accagctgcc 660
acatcctggg ctggggcaag acagcagatg gtgatttccc tgacaccatc cagtgtgcat 720
acatccacct ggtgtcccgt gaggagtgtg agcatgccta ccctggccag atcacccaga 780
acatgttgtg tgctggggat gagaagtacg ggaaggattc ctgccagggt gattctgggg 840
gtccgctggt atgtggagac cacctccgag gccttgtgtc atggggtaac atcccctgtg 900
gatcaaagga gaagccagga gtctacacca acgtctgcag atacacgaac tggatccaaa 960
aaaccattca ggccaagtga ccctgacatg tgacatctac ctcccgacct accaccccac 1020
tggctggttc cagaacgtct ctcacctaga ccttgcctcc cctcctctcc tgcccagctc 1080
tgaccctgat gcttaataaa cgcagcgacg tgagggtcct gattctccct ggttttaccc 1140
cagctccatc cttgcatcac tggggaggac gtgatgagtg aggacttggg tcctcggtct 1200
tacccccacc actaagagaa tacaggaaaa tcccttctag gcatctcctc tccccaaccc 1260
ttccacacgt ttgatttctt cctgcagagg cccagccacg tgtctggaat cccagctccg 1320
ctgcttactg tcggtgtccc cttgggatgt acctttcttc actgcagatt tctcacctgt 1380
aagatgaaga taaggatgat acagtctcca tcaggcagtg gctgttggaa agatttaaga 1440
tttcacacct atgacataca tgggatagca cctgggccgc catgcactca ataaagaatg 1500
tatttt 1506
<210>56
<211>2907
<212>DNA
<213>人
<400>56
gccatctggg cccaggcccc atgccccgag gaggggtggt ctgaagccca ccagagcccc 60
ctgccagact gtctgcctcc cttctgactg tggccgcttg gcatggccag caacagcagc 120
tcctgcccga cacctggggg cgggcacctc aatgggtacc cggtgcctcc ctacgccttc 180
ttcttccccc ctatgctggg tggactctcc ccgccaggcg ctctgaccac tctccagcac 240
cagcttccag ttagtggata tagcacacca tccccagcca ccattgagac ccagagcagc 300
agttctgaag agatagtgcc cagccctccc tcgccacccc ctctaccccg catctacaag 360
ccttgctttg tctgtcagga caagtcctca ggctaccact atggggtcag cgcctgtgag 420
ggctgcaagg gcttcttccg ccgcagcatc cagaagaaca tggtgtacac gtgtcaccgg 480
gacaagaact gcatcatcaa caaggtgacc cggaaccgct gccagtactg ccgactgcag 540
aagtgctttg aagtgggcat gtccaaggag tctgtgagaa acgaccgaaa caagaagaag 600
aaggaggtgc ccaagcccga gtgctctgag agctacacgc tgacgccgga ggtgggggag 660
ctcattgaga aggtgcgcaa agcgcaccag gaaaccttcc ctgccctctg ccagctgggc 720
aaatacacta cgaacaacag ctcagaacaa cgtgtctctc tggacattga cctctgggac 780
aagttcagtg aactctccac caagtgcatc attaagactg tggagttcgc caagcagctg 840
cccggcttca ccaccctcac catcgccgac cagatcaccc tcctcaaggc tgcctgcctg 900
gacatcctga tcctgcggat ctgcacgcgg tacacgcccg agcaggacac catgaccttc 960
tcggacgggc tgaccctgaa ccggacccag atgcacaacg ctggcttcgg ccccctcacc 1020
gacctggtct ttgccttcgc caaccagctg ctgcccctgg agatggatga tgcggagacg 1080
gggctgctca gcgccatctg cctcatctgc ggagaccgcc aggacctgga gcagccggac 1140
cgggtggaca tgctgcagga gccgctgctg gaggcgctaa aggtctacgt gcggaagcgg 1200
aggcccagcc gcccccacat gttccccaag atgctaatga agattactga cctgcgaagc 1260
atcagcgcca agggggctga gcgggtgatc acgctgaaga tggagatccc gggctccatg 1320
ccgcctctca tccaggaaat gttggagaac tcagagggcc tggacactct gagcggacag 1380
ccggggggtg gggggcggga cgggggtggc ctggcccccc cgccaggcag ctgtagcccc 1440
agcctcagcc ccagctccaa cagaagcagc ccggccaccc actccccgtg accgcccacg 1500
ccacatggac acagccctcg ccctccgccc cggcttttct ctgcctttct accgaccatg 1560
tgaccccgca ccagccctgc ccccacctgc cctcccgggc agtactgggg accttccctg 1620
ggggacgggg agggaggagg cagcgactcc ttggacagag gcctgggccc tcagtggact 1680
gcctgctccc acagcctggg ctgacgtcag aggccgaggc caggaactga gtgaggcccc 1740
tggtcctggg tctcaggatg ggtcctgggg gcctcgtgtt catcaagaca cccctctgcc 1800
cagctcacca catcttcatc accagcaaac gccaggactt ggctccccca tcctcagaac 1860
tcacaagcca ttgctcccca gctggggaac ctcaacctcc cccctgcctc ggttggtgac 1920
agagggggtg ggacaggggc ggggggttcc ccctgtacat accctgccat accaacccca 1980
ggtattaatt ctcgctggtt ttgtttttat tttaattttt ttgttttgat ttttttaata 2040
agaattttca ttttaagcac atttatactg aaggaatttg tgctgtgtat tggggggagc 2100
tggatccaga gctggagggg gtgggtccgg gggagggagt ggctcggaag gggcccccac 2160
tctcctttca tgtccctgtg ccccccagtt ctcctcctca gccttttcct cctcagtttt 2220
ctctttaaaa ctgtgaagta ctaactttcc aaggcctgcc ttcccctccc tcccactgga 2280
gaagccgcca gcccctttct ccctctgcct gaccactggg tgtggacggt gtggggcagc 2340
cctgaaagga caggctcctg gccttggcac ttgcctgcac ccaccatgag gcatggagca 2400
gggcagagca agggccccgg gacagagttt tcccagacct ggctcctcgg cagagctgcc 2460
tcccgtcagg gcccacatca tctaggctcc ccagccccca ctgtgaaggg gctggccagg 2520
ggcccgagct gcccccaccc ccggcctcag ccaccagcac ccccataggg cccccagaca 2580
ccacacacat gcgcgtgcgc acacacacaa acacacacac actggacagt agatgggccg 2640
acacacactt ggcccgagtt cctccatttc cctggcctgc cccccacccc caacctgtcc 2700
cacccccgtg ccccctcctt accccgcagg acgggcctac aggggggtct cccctcaccc 2760
ctgcaccccc agctggggga gctggctctg ccccgacctc cttcaccagg ggttggggcc 2820
ccttcccctg gagcccgtgg gtgcacctgt tactgttggg ctttccactg agatctactg 2880
gataaagaat aaagttctat ttattct 2907
<210>57
<211>2907
<212>DNA
<213>人
<400>57
gccatctggg cccaggcccc atgccccgag gaggggtggt ctgaagccca ccagagcccc 60
ctgccagact gtctgcctcc cttctgactg tggccgcttg gcatggccag caacagcagc 120
tcctgcccga cacctggggg cgggcacctc aatgggtacc cggtgcctcc ctacgccttc 180
ttcttccccc ctatgctggg tggactctcc ccgccaggcg ctctgaccac tctccagcac 240
cagcttccag ttagtggata tagcacacca tccccagcca ccattgagac ccagagcagc 300
agttctgaag agatagtgcc cagccctccc tcgccacccc ctctaccccg catctacaag 360
ccttgctttg tctgtcagga caagtcctca ggctaccact atggggtcag cgcctgtgag 420
ggctgcaagg gcttcttccg ccgcagcatc cagaagaaca tggtgtacac gtgtcaccgg 480
gacaagaact gcatcatcaa caaggtgacc cggaaccgct gccagtactg ccgactgcag 540
aagtgctttg aagtgggcat gtccaaggag tctgtgagaa acgaccgaaa caagaagaag 600
aaggaggtgc ccaagcccga gtgctctgag agctacacgc tgacgccgga ggtgggggag 660
ctcattgaga aggtgcgcaa agcgcaccag gaaaccttcc ctgccctctg ccagctgggc 720
aaatacacta cgaacaacag ctcagaacaa cgtgtctctc tggacattga cctctgggac 780
aagttcagtg aactctccac caagtgcatc attaagactg tggagttcgc caagcagctg 840
cccggcttca ccaccctcac catcgccgac cagatcaccc tcctcaaggc tgcctgcctg 900
gacatcctga tcctgcggat ctgcacgcgg tacacgcccg agcaggacac catgaccttc 960
tcggacgggc tgaccctgaa ccggacccag atgcacaacg ctggcttcgg ccccctcacc 1020
gacctggtct ttgccttcgc caaccagctg ctgcccctgg agatggatga tgcggagacg 1080
gggctgctca gcgccatctg cctcatctgc ggagaccgcc aggacctgga gcagccggac 1140
cgggtggaca tgctgcagga gccgctgctg gaggcgctaa aggtctacgt gcggaagcgg 1200
aggcccagcc gcccccacat gttccccaag atgctaatga agattactga cctgcgaagc 1260
atcagcgcca agggggctga gcgggtgatc acgctgaaga tggagatccc gggctccatg 1320
ccgcctctca tccaggaaat gttggagaac tcagagggcc tggacactct gagcggacag 1380
ccggggggtg gggggcggga cgggggtggc ctggcccccc cgccaggcag ctgtagcccc 1440
agcctcagcc ccagctccaa cagaagcagc ccggccaccc actccccgtg accgcccacg 1500
ccacatggac acagccctcg ccctccgccc cggcttttct ctgcctttct accgaccatg 1560
tgaccccgca ccagccctgc ccccacctgc cctcccgggc agtactgggg accttccctg 1620
ggggacgggg agggaggagg cagcgactcc ttggacagag gcctgggccc tcagtggact 1680
gcctgctccc acagcctggg ctgacgtcag aggccgaggc caggaactga gtgaggcccc 1740
tggtcctggg tctcaggatg ggtcctgggg gcctcgtgtt catcaagaca cccctctgcc 1800
cagctcacca catcttcatc accagcaaac gccaggactt ggctccccca tcctcagaac 1860
tcacaagcca ttgctcccca gctggggaac ctcaacctcc cccctgcctc ggttggtgac 1920
agagggggtg ggacaggggc ggggggttcc ccctgtacat accctgccat accaacccca 1980
ggtattaatt ctcgctggtt ttgtttttat tttaattttt ttgttttgat ttttttaata 2040
agaattttca ttttaagcac atttatactg aaggaatttg tgctgtgtat tggggggagc 2100
tggatccaga gctggagggg gtgggtccgg gggagggagt ggctcggaag gggcccccac 2160
tctcctttca tgtccctgtg ccccccagtt ctcctcctca gccttttcct cctcagtttt 2220
ctctttaaaa ctgtgaagta ctaactttcc aaggcctgcc ttcccctccc tcccactgga 2280
gaagccgcca gcccctttct ccctctgcct gaccactggg tgtggacggt gtggggcagc 2340
cctgaaagga caggctcctg gccttggcac ttgcctgcac ccaccatgag gcatggagca 2400
gggcagagca agggccccgg gacagagttt tcccagacct ggctcctcgg cagagctgcc 2460
tcccgtcagg gcccacatca tctaggctcc ccagccccca ctgtgaaggg gctggccagg 2520
ggcccgagct gcccccaccc ccggcctcag ccaccagcac ccccataggg cccccagaca 2580
ccacacacat gcgcgtgcgc acacacacaa acacacacac actggacagt agatgggccg 2640
acacacactt ggcccgagtt cctccatttc cctggcctgc cccccacccc caacctgtcc 2700
cacccccgtg ccccctcctt accccgcagg acgggcctac aggggggtct cccctcaccc 2760
ctgcaccccc agctggggga gctggctctg ccccgacctc cttcaccagg ggttggggcc 2820
ccttcccctg gagcccgtgg gtgcacctgt tactgttggg ctttccactg agatctactg 2880
gataaagaat aaagttctat ttattct 2907
<210>58
<211>5026
<212>DNA
<213>人
<400>58
agaggaggaa attgttcctc gtctgataag acaacagtgg agaaaggacg catgctgttt 60
cttagggaca cggctgactt ccagatatga ccatgtattt gtggcttaaa ctcttggcat 120
ttggctttgc ctttctggac acagaagtat ttgtgacagg gcaaagccca acaccttccc 180
ccactggatt gactacagca aagatgccca gtgttccact ttcaagtgac cccttaccta 240
ctcacaccac tgcattctca cccgcaagca cctttgaaag agaaaatgac ttctcagaga 300
ccacaacttc tcttagtcca gacaatactt ccacccaagt atccccggac tctttggata 360
atgctagtgc ttttaatacc acaggtgttt catcagtaca gacgcctcac cttcccacgc 420
acgcagactc gcagacgccc tctgctggaa ctgacacgca gacattcagc ggctccgccg 480
ccaatgcaaa actcaaccct accccaggca gcaatgctat ctcagatgtc ccaggagaga 540
ggagtacagc cagcaccttt cctacagacc cagtttcccc attgacaacc accctcagcc 600
ttgcacacca cagctctgct gccttacctg cacgcacctc caacaccacc atcacagcga 660
acacctcaga tgcctacctt aatgcctctg aaacaaccac tctgagccct tctggaagcg 720
ctgtcatttc aaccacaaca atagctacta ctccatctaa gccaacatgt gatgaaaaat 780
atgcaaacat cactgtggat tacttatata acaaggaaac taaattattt acagcaaagc 840
taaatgttaa tgagaatgtg gaatgtggaa acaatacttg cacaaacaat gaggtgcata 900
accttacaga atgtaaaaat gcgtctgttt ccatatctca taattcatgt actgctcctg 960
ataagacatt aatattagat gtgccaccag gggttgaaaa gtttcagtta catgattgta 1020
cacaagttga aaaagcagat actactattt gtttaaaatg gaaaaatatt gaaaccttta 1080
cttgtgatac acagaatatt acctacagat ttcagtgtgg taatatgata tttgataata 1140
aagaaattaa attagaaaac cttgaacccg aacatgagta taagtgtgac tcagaaatac 1200
tctataataa ccacaagttt actaacgcaa gtaaaattat taaaacagat tttgggagtc 1260
caggagagcc tcagattatt ttttgtagaa gtgaagctgc acatcaagga gtaattacct 1320
ggaatccccc tcaaagatca tttcataatt ttaccctctg ttatataaaa gagacagaaa 1380
aagattgcct caatctggat aaaaacctga tcaaatatga tttgcaaaat ttaaaacctt 1440
atacgaaata tgttttatca ttacatgcct acatcattgc aaaagtgcaa cgtaatggaa 1500
gtgctgcaat gtgtcatttc acaactaaaa gtgctcctcc aagccaggtc tggaacatga 1560
ctgtctccat gacatcagat aatagtatgc atgtcaagtg taggcctccc agggaccgta 1620
atggccccca tgaacgttac catttggaag ttgaagctgg aaatactctg gttagaaatg 1680
agtcgcataa gaattgcgat ttccgtgtaa aagatcttca atattcaaca gactacactt 1740
ttaaggccta ttttcacaat ggagactatc ctggagaacc ctttatttta catcattcaa 1800
catcttataa ttctaaggca ctgatagcat ttctggcatt tctgattatt gtgacatcaa 1860
tagccctgct tgttgttctc tacaaaatct atgatctaca taagaaaaga tcctgcaatt 1920
tagatgaaca gcaggagctt gttgaaaggg atgatgaaaa acaactgatg aatgtggagc 1980
caatccatgc agatattttg ttggaaactt ataagaggaa gattgctgat gaaggaagac 2040
tttttctggc tgaatttcag agcatcccgc gggtgttcag caagtttcct ataaaggaag 2100
ctcgaaagcc ctttaaccag aataaaaacc gttatgttga cattcttcct tatgattata 2160
accgtgttga actctctgag ataaacggag atgcagggtc aaactacata aatgccagct 2220
atattgatgg tttcaaagaa cccaggaaat acattgctgc acaaggtccc agggatgaaa 2280
ctgttgatga tttctggagg atgatttggg aacagaaagc cacagttatt gtcatggtca 2340
ctcgatgtga agaaggaaac aggaacaagt gtgcagaata ctggccgtca atggaagagg 2400
gcactcgggc ttttggagat gttgttgtaa agatcaacca gcacaaaaga tgtccagatt 2460
acatcattca gaaattgaac attgtaaata aaaaagaaaa agcaactgga agagaggtga 2520
ctcacattca gttcaccagc tggccagacc acggggtgcc tgaggatcct cacttgctcc 2580
tcaaactgag aaggagagtg aatgccttca gcaatttctt cagtggtccc attgtggtgc 2640
actgcagtgc tggtgttggg cgcacaggaa cctatatcgg aattgatgcc atgctagaag 2700
gcctggaagc cgagaacaaa gtggatgttt atggttatgt tgtcaagcta aggcgacaga 2760
gatgcctgat ggttcaagta gaggcccagt acatcttgat ccatcaggct ttggtggaat 2820
acaatcagtt tggagaaaca gaagtgaatt tgtctgaatt acatccatat ctacataaca 2880
tgaagaaaag ggatccaccc agtgagccgt ctccactaga ggctgaattc cagagacttc 2940
cttcatatag gagctggagg acacagcaca ttggaaatca agaagaaaat aaaagtaaaa 3000
acaggaattc taatgtcatc ccatatgact ataacagagt gccacttaaa catgagctgg 3060
aaatgagtaa agagagtgag catgattcag atgaatcctc tgatgatgac agtgattcag 3120
aggaaccaag caaatacatc aatgcatctt ttataatgag ctactggaaa cctgaagtga 3180
tgattgctgc tcagggacca ctgaaggaga ccattggtga cttttggcag atgatcttcc 3240
aaagaaaagt caaagttatt gttatgctga cagaactgaa acatggagac caggaaatct 3300
gtgctcagta ctggggagaa ggaaagcaaa catatggaga tattgaagtt gacctgaaag 3360
acacagacaa atcttcaact tatacccttc gtgtctttga actgagacat tccaagagga 3420
aagactctcg aactgtgtac cagtaccaat atacaaactg gagtgtggag cagcttcctg 3480
cagaacccaa ggaattaatc tctatgattc aggtcgtcaa acaaaaactt ccccagaaga 3540
attcctctga agggaacaag catcacaaga gtacacctct actcattcac tgcagggatg 3600
gatctcagca aacgggaata ttttgtgctt tgttaaatct cttagaaagt gcggaaacag 3660
aagaggtagt ggatattttt caagtggtaa aagctctacg caaagctagg ccaggcatgg 3720
tttccacatt cgagcaatat caattcctat atgacgtcat tgccagcacc taccctgctc 3780
agaatggaca agtaaagaaa aacaaccatc aagaagataa aattgaattt gataatgaag 3840
tggacaaagt aaagcaggat gctaattgtg ttaatccact tggtgcccca gaaaagctcc 3900
ctgaagcaaa ggaacaggct gaaggttctg aacccacgag tggcactgag gggccagaac 3960
attctgtcaa tggtcctgca agtccagctt taaatcaagg ttcataggaa aagacataaa 4020
tgaggaaact ccaaacctcc tgttagctgt tatttctatt tttgtagaag taggaagtga 4080
aaataggtat acagtggatt aattaaatgc agcgaaccaa tatttgtaga agggttatat 4140
tttactactg tggaaaaata tttaagatag ttttgccaga acagtttgta cagacgtatg 4200
cttattttaa aattttatct cttattcagt aaaaaacaac ttctttgtaa tcgttatgtg 4260
tgtatatgta tgtgtgtatg ggtgtgtgtt tgtgtgagag acagagaaag agagagaatt 4320
ctttcaagtg aatctaaaag cttttgcttt tcctttgttt ttatgaagaa aaaatacatt 4380
ttatattaga agtgttaact tagcttgaag gatctgtttt taaaaatcat aaactgtgtg 4440
cagactcaat aaaatcatgt acatttctga aatgacctca agatgtcctc cttgttctac 4500
tcatatatat ctatcttata tacttactat tttacttcta gagatagtac ataaaggtgg 4560
tatgtgtgtg tatgctacta caaaaaagtt gttaactaaa ttaacattgg gaaatcttat 4620
attccatata ttagcattta gtccaatgtc tttttaagct tatttaatta aaaaatttcc 4680
agtgagctta tcatgctgtc tttacatggg gttttcaatt ttgcatgctc gattattccc 4740
tgtacaatat ttaaaattta ttgcttgata cttttgacaa caaattaggt tttgtacaat 4800
tgaacttaaa taaatgtcat taaaataaat aaatgcaata tgtattaata ttcattgtat 4860
aaaaatagaa gaatacaaac atatttgtta aatatttaca tatgaaattt aatatagcta 4920
tttttatgga atttttcatt gatatgaaaa atatgatatt gcatatgcat agttcccatg 4980
ttaaatccca ttcataactt tcattaaagc atttactttg aatttc 5026
<210>59
<211>625
<212>DNA
<213>人
<400>59
aggcgggccg ctcccacttc ggcacgaggg gcacgaggta aatcttttct gcttactgaa 60
aaggaagagt ctgatgatta gttactgatc ctctttgcat ttgtaaagct ttggagatat 120
tgaatcatgt taccatttct gtttttttcc accctgtttt cttccatatt tactgaagct 180
cagaagcagt attgggtctg caactcatcc gatgcaagta tttcatacac ctactgtgat 240
aaaatgcaat acccaatttc aattaatgtt aacccctgta tagaattgaa aggatccaaa 300
ggattattgc acattttcta cattccaagg agagatttaa agcaattata tttcaatctc 360
tatataactg tcaacaccat gaatcttcca aagcgcaaag aagttatttg ccgaggatct 420
gatgacgatt actctttttg cagagctctg aagggagaga ctgtgaatac aacaatatca 480
ttctccttca agggaataaa attttctaag ggaaaataca aatgtgttgt tgaagctatt 540
tctgggagcc cagaagaaat gctcttttgc ttggagtttg tcatcctaca ccaacctaat 600
tcaaattaga ataaattgag tattt 625
<210>60
<211>2088
<212>DNA
<213>人
<400>60
gaattcggca cgagcgcgcg gcgaatctca acgctgcgcc gtctgcgggc gcttccgggc 60
caccagtttc tctgctttcc accctggcgc cccccagccc tggctcccca gctgcgctgc 120
cccgggcgtc cacgccctgc gggcttagcg ggttcagtgg gctcaatctg cgcagcgcca 180
cctccatgtt gaccaagcct ctacaggggc ctcccgcgcc ccccgggacc cccacgccgc 240
cgccaggagg caaggatcgg gaagcgttcg aggccgagta tcgactcggc cccctcctgg 300
gtaagggggg ctttggcacc gtcttcgcag gacaccgcct cacagatcga ctccaggtgg 360
ccatcaaagt gattccccgg aatcgtgtgc tgggctggtc ccccttgtca gactcagtca 420
catgcccact cgaagtcgca ctgctatgga aagtgggtgc aggtggtggg caccctggcg 480
tgatccgcct gcttgactgg tttgagacac aggaaggctt catgctggtc ctcgagcggc 540
ctttgcccgc ccaggatctc tttgactata tcacagagaa gggcccactg ggtgaaggcc 600
caagccgctg cttctttggc caagtagtgg cagccatcca gcactgccat tcccgtggag 660
ttgtccatcg tgacatcaag gatgagaaca tcctgataga cctacgccgt ggctgtgcca 720
aactcattga ttttggttct ggtgccctgc ttcatgatga accctacact gactttgatg 780
ggacaagggt gtacagcccc ccagagtgga tctctcgaca ccagtaccat gcactcccgg 840
ccactgtctg gtcactgggc atcctcctct atgacatggt gtgtggggac attccctttg 900
agagggacca ggagattctg gaagctgagc tccacttccc agcccatgtc tccccagact 960
gctgtgccct aatccgccgg tgcctggccc ccaaaccttc ttcccgaccc tcactggaag 1020
agatcctgct ggacccctgg atgcaaacac cagccgagga tgttacccct caacccctcc 1080
aaaggaggcc ctgccccttt ggcctggtcc ttgctaccct aagcctggcc tggcctggcc 1140
tggcccccaa tggtcagaag agccatccca tggccatgtc acagggatag atggacattt 1200
gttgacttgg ttttacaggt cattaccagt cattaaagtc cagtattact aaggtaaggg 1260
attgaggatc aggggttaga agacataaac caagtttgcc cagttccctt cccaatccta 1320
caaaggagcc ttcctcccag aacctgtggt ccctgatttt ggagggggaa cttcttgctt 1380
ctcattttgc taaggaagtt tattttggtg aagttgttcc cattttgagc cccgggactc 1440
ttattttgat gatgtgtcac cccacattgg cacctcctac taccaccaca caaacttagt 1500
tcatatgctt ttacttgggc aagggtgctt tccttccaat accccagtag cttttatttt 1560
agtaaaggga ccctttcccc tagcctaggg tcccatattg ggtcaagctg cttacctgcc 1620
tcagcccagg attttttatt ttgggggagg taatgccctg ttgttacccc aaggcttctt 1680
tttttttttt tttttttttg ggtgagggga ccctactttg ttatcccaag tgctcttatt 1740
ctggtgagaa gaaccttaat tccataattt gggaaggaat ggaagatgga caccaccgga 1800
caccaccaga caataggatg ggatggatgg ttttttgggg gatgggctag gggaaataag 1860
gcttgctgtt tgttttcctg gggcgctccc tccaattttg cagatttttg caacctcctc 1920
ctgagccggg attgtccaat tactaaaatg taaataatca cgtattgtgg ggaggggagt 1980
tccaagtgtg ccctcctttt ttttcctgcc tggattattt aaaaagccat gtgtggaaac 2040
ccactattta ataaaagtaa tagaatcaga aaaaaaaaaa aaaaaaaa 2088
<210>61
<211>2270
<212>DNA
<213>人
<400>61
ctcctccagc ctctcacact ctcctcagct ctctcatctc ctggaaccat ggccagcaca 60
tccaccacca tcaggagcca cagcagcagc cgccggggtt tcagtgccaa ctcagccagg 120
ctccctgggg tcagccgctc tggcttcagc agcgtctccg tgtcccgctc caggggcagt 180
ggtggcctgg gtggtgcatg tggaggagct ggctttggca gccgcagtct gtatggcctg 240
gggggctcca agaggatctc cattggaggg ggcagctgtg ccatcagtgg cggctatggc 300
agcagagccg gaggcagcta tggctttggt ggcgccggga gtggatttgg tttcggtggt 360
ggagccggca ttggctttgg tctgggtggt ggagccggcc ttgctggtgg ctttgggggc 420
cctggcttcc ctgtgtgccc ccctggaggc atccaagagg tcaccgtcaa ccagagtctc 480
ctgactcccc tcaacctgca aatcgatccc accatccagc gggtgcgggc tgaggagcgt 540
gaacagatca agaccctcaa caacaagttt gcctccttca tcgacaaggt gcggttcctg 600
gagcagcaga acaaggttct ggaaacaaag tggaccctgc tgcaggagca gggcaccaag 660
actgtgaggc agaacctgga gccgttgttc gagcagtaca tcaacaacct caggaggcag 720
ctggacagca ttgtcgggga acggggccgc ctggactcag agctcagagg catgcaggac 780
ctggtggagg acttcaagaa caaatatgag gatgaaatca acaagcgcac agcagcagag 840
aatgaatttg tgactctgaa gaaggatgtg gatgctgcct acatgaacaa ggttgaactg 900
caagccaagg cagacactct cacagacgag atcaacttcc tgagagcctt gtatgatgca 960
gagctgtccc agatgcagac ccacatctca gacacatctg tggtgctgtc catggacaac 1020
aaccgcaacc tggacctgga cagcatcatc gctgaggtca aggcccaata tgaggagatt 1080
gctcagagaa gccgggctga ggctgagtcc tggtaccaga ccaagtacga ggagctgcag 1140
gtcacagcag gcagacatgg ggacgacctg cgcaacacca agcaggagat tgctgagatc 1200
aaccgcatga tccagaggct gagatctgag atcgaccacg tcaagaagca gtgcgccaac 1260
ctgcaggccg ccattgctga tgctgagcag cgtggggaga tggccctcaa ggatgccaag 1320
aacaagctgg aagggctgga ggatgccctg cagaaggcca agcaggacct ggcccggctg 1380
ctgaaggagt accaggagct gatgaatgtc aagctggccc tggacgtgga gatcgccacc 1440
taccgcaagc tgctggaggg tgaggagtgc aggctgaatg gcgaaggcgt tggacaagtc 1500
aacatctctg tggtgcagtc caccgtctcc agtggctatg gcggtgccag tggtgtcggc 1560
agtggcttag gcctgggtgg aggaagcagc tactcctatg gcagtggtct tggcgttgga 1620
ggtggcttca gttccagcag tggcagagcc attgggggtg gcctcagctc tgttggaggc 1680
ggcagttcca ccatcaagta caccaccacc tcctcctcca gcaggaagag ctataagcac 1740
taaagtgcgt ctgctagctc tcggtcccac agtcctcagg cccctctctg gctgcagagc 1800
cctctcctca ggttgcctgt cctctcctgg cctccagtct cccctgctgt cccaggtaga 1860
gctggggatg aatgcttagt gccctcactt cttctctctc tctctatacc atctgagcac 1920
ccattgctca ccatcagatc aacctctgat tttacatcat gatgtaatca ccactggagc 1980
ttcactgtta ctaaattatt aatttcttgc ctccagtgtt ctatctctga ggctgagcat 2040
tataagaaaa tgacctctgc tccttttcat tgcagaaaat tgccaggggc ttatttcaga 2100
acaacttcca cttactttcc actggctctc aaactctcta acttataagt gttgtgaacc 2160
cccacccagg cagtatccat gaaagcacaa gtgactagtc ctatgatgta caaagcctgt 2220
atctctgtga tgatttctgt gctcttcact gtttgcaatt gctaaataaa 2270
<210>62
<211>2048
<212>DNA
<213>人
<400>62
atgtgaaggc acaagctgct gttatataca acagagtgaa ctgagcatca gtcagaaaaa 60
gtctatgttt gcagaaatac agatccaaga caaagacagg atgggcactg ctggaaaagt 120
tattaaatgc aaagcagctg tgctttggga gcagaagcaa cccttctcca ttgaggaaat 180
agaagttgcc ccaccaaaga ctaaagaagt tcgcattaag attttggcca caggaatctg 240
tcgcacagat gaccatgtga taaaaggaac aatggtgtcc aagtttccag tgattgtggg 300
acatgaggca actgggattg tagagagcat tggagaagga gtgactacag tgaaaccagg 360
tgacaaagtc atccctctct ttctgccaca atgtagagaa tgcaatgctt gtcgcaaccc 420
agatggcaac ctttgcatta ggagcgatat tactggtcgt ggagtactgg ctgatggcac 480
caccagattt acatgcaagg gcaaaccagt acaccacttc atgaacacca gtacatttac 540
cgagtacaca gtggtggatg aatcttctgt tgctaagatt gatgatgcag ctcctcctga 600
gaaagtctgt ttaattggct gtgggttttc cactggatat ggcgctgctg ttaaaactgg 660
caaggtcaaa cctggttcca cttgcgtcgt ctttggcctg ggaggagttg gcctgtcagt 720
catcatgggc tgtaagtcag ctggtgcatc taggatcatt gggattgacc tcaacaaaga 780
caaatttgag aaggccatgg ctgtaggtgc cactgagtgt atcagtccca aggactctac 840
caaacccatc agtgaggtgc tgtcagaaat gacaggcaac aacgtgggat acacctttga 900
agttattggg catcttgaaa ccatgattga tgccctggca tcctgccaca tgaactatgg 960
gaccagcgtg gttgtaggag ttcctccatc agccaagatg ctcacctatg acccgatgtt 1020
gctcttcact ggacgcacat ggaagggatg tgtctttgga ggtttgaaaa gcagagatga 1080
tgtcccaaaa ctagtgactg agttcctggc aaagaaattt gacctggacc agttgataac 1140
tcatgtttta ccatttaaaa aaatcagtga aggatttgag ctgctcaatt caggacaaag 1200
cattcgaacg gtcctgacgt tttgagatcc aaagtggcag gaggtctgtg ttgtcatggt 1260
gaactggagt ttctcttgtg agagttccct catctgaaat catgtatctg tctcacaaat 1320
acaagcataa gtagaagatt tgttgaagac atagaaccct tataaagaat tattaacctt 1380
tataaacatt taaagtcttg tgagcacctg ggaattagta taataacaat gttaatattt 1440
ttgatttaca ttttgtaagg ctataattgt atcttttaag aaaacataca cttggatttc 1500
tatgttgaaa tggagatttt taagagtttt aaccagctgc tgcagatata taactcaaaa 1560
cagatatagc gtataaagat atagtaaatg catctcccag agtaatattc acttaacaca 1620
ttgaaactat tattttttag atttgaatat aaatgtattt tttaaacact tgttatgagt 1680
taacttggat tacattttga aatcagttca ttccatgatg catattactg gattagatta 1740
agaaagacag aaaagattaa gggacgggca catttttcaa cgattaagaa tcatcattac 1800
ataacttggt gaaactgaaa aagtatatca tatgggtaca caaggctatt tgccagcata 1860
tattaatatt ttagaaaata ttccttttgt aatactgaat ataaacatag agctagagtc 1920
atattatcat acttatcata atgttcaatt tgatacagta gaattgcaag tccctaagtc 1980
cctattcact gtgcttagta gtgactccat ttaataaaaa gtgtttttag tttttaacaa 2040
ctaaaccg 2048
<210>63
<211>2048
<212>DNA
<213>人
<400>63
atgtgaaggc acaagctgct gttatataca acagagtgaa ctgagcatca gtcagaaaaa 60
gtctatgttt gcagaaatac agatccaaga caaagacagg atgggcactg ctggaaaagt 120
tattaaatgc aaagcagctg tgctttggga gcagaagcaa cccttctcca ttgaggaaat 180
agaagttgcc ccaccaaaga ctaaagaagt tcgcattaag attttggcca caggaatctg 240
tcgcacagat gaccatgtga taaaaggaac aatggtgtcc aagtttccag tgattgtggg 300
acatgaggca actgggattg tagagagcat tggagaagga gtgactacag tgaaaccagg 360
tgacaaagtc atccctctct ttctgccaca atgtagagaa tgcaatgctt gtcgcaaccc 420
agatggcaac ctttgcatta ggagcgatat tactggtcgt ggagtactgg ctgatggcac 480
caccagattt acatgcaagg gcaaaccagt acaccacttc atgaacacca gtacatttac 540
cgagtacaca gtggtggatg aatcttctgt tgctaagatt gatgatgcag ctcctcctga 600
gaaagtctgt ttaattggct gtgggttttc cactggatat ggcgctgctg ttaaaactgg 660
caaggtcaaa cctggttcca cttgcgtcgt ctttggcctg ggaggagttg gcctgtcagt 720
catcatgggc tgtaagtcag ctggtgcatc taggatcatt gggattgacc tcaacaaaga 780
caaatttgag aaggccatgg ctgtaggtgc cactgagtgt atcagtccca aggactctac 840
caaacccatc agtgaggtgc tgtcagaaat gacaggcaac aacgtgggat acacctttga 900
agttattggg catcttgaaa ccatgattga tgccctggca tcctgccaca tgaactatgg 960
gaccagcgtg gttgtaggag ttcctccatc agccaagatg ctcacctatg acccgatgtt 1020
gctcttcact ggacgcacat ggaagggatg tgtctttgga ggtttgaaaa gcagagatga 1080
tgtcccaaaa ctagtgactg agttcctggc aaagaaattt gacctggacc agttgataac 1140
tcatgtttta ccatttaaaa aaatcagtga aggatttgag ctgctcaatt caggacaaag 1200
cattcgaacg gtcctgacgt tttgagatcc aaagtggcag gaggtctgtg ttgtcatggt 1260
gaactggagt ttctcttgtg agagttccct catctgaaat catgtatctg tctcacaaat 1320
acaagcataa gtagaagatt tgttgaagac atagaaccct tataaagaat tattaacctt 1380
tataaacatt taaagtcttg tgagcacctg ggaattagta taataacaat gttaatattt 1440
ttgatttaca ttttgtaagg ctataattgt atcttttaag aaaacataca cttggatttc 1500
tatgttgaaa tggagatttt taagagtttt aaccagctgc tgcagatata taactcaaaa 1560
cagatatagc gtataaagat atagtaaatg catctcccag agtaatattc acttaacaca 1620
ttgaaactat tattttttag atttgaatat aaatgtattt tttaaacact tgttatgagt 1680
taacttggat tacattttga aatcagttca ttccatgatg catattactg gattagatta 1740
agaaagacag aaaagattaa gggacgggca catttttcaa cgattaagaa tcatcattac 1800
ataacttggt gaaactgaaa aagtatatca tatgggtaca caaggctatt tgccagcata 1860
tattaatatt ttagaaaata ttccttttgt aatactgaat ataaacatag agctagagtc 1920
atattatcat acttatcata atgttcaatt tgatacagta gaattgcaag tccctaagtc 1980
cctattcact gtgcttagta gtgactccat ttaataaaaa gtgtttttag tttttaacaa 2040
ctaaaccg 2048
<210>64
<211>2816
<212>DNA
<213>人
<400>64
tcgttgatat caaagacagt tgaaggaaat gaattttgaa acttcacggt gtgccaccct 60
acagtactgc cctgaccctt acatccagcg tttcgtagaa acccagctca tttctcttgg 120
aaagaaagtt attaccgatc caccatgtcc cagagcacac agacaaatga attcctcagt 180
ccagaggttt tccagcatat ctgggatttt ctggaacagc ctatatgttc agttcagccc 240
attgacttga actttgtgga tgaaccatca gaagatggtg cgacaaacaa gattgagatt 300
agcatggact gtatccgcat gcaggactcg gacctgagtg accccatgtg gccacagtac 360
acgaacctgg ggctcctgaa cagcatggac cagcagattc agaacggctc ctcgtccacc 420
agtccctata acacagacca cgcgcagaac agcgtcacgg cgccctcgcc ctacgcacag 480
cccagctcca ccttcgatgc tctctctcca tcacccgcca tcccctccaa caccgactac 540
ccaggcccgc acagtttcga cgtgtccttc cagcagtcga gcaccgccaa gtcggccacc 600
tggacgtatt ccactgaact gaagaaactc tactgccaaa ttgcaaagac atgccccatc 660
cagatcaagg tgatgacccc acctcctcag ggagctgtta tccgcgccat gcctgtctac 720
aaaaaagctg agcacgtcac ggaggtggtg aagcggtgcc ccaaccatga gctgagccgt 780
gaattcaacg agggacagat tgcccctcct agtcatttga ttcgagtaga ggggaacagc 840
catgcccagt atgtagaaga tcccatcaca ggaagacaga gtgtgctggt accttatgag 900
ccaccccagg ttggcactga attcacgaca gtcttgtaca atttcatgtg taacagcagt 960
tgtgttggag ggatgaaccg ccgtccaatt ttaatcattg ttactctgga aaccagagat 1020
gggcaagtcc tgggccgacg ctgctttgag gcccggatct gtgcttgccc aggaagagac 1080
aggaaggcgg atgaagatag catcagaaag cagcaagttt cggacagtac aaagaacggt 1140
gatggtacga agcgcccgtt tcgtcagaac acacatggta tccagatgac atccatcaag 1200
aaacgaagat ccccagatga tgaactgtta tacttaccag tgaggggccg tgagacttat 1260
gaaatgctgt tgaagatcaa agagtccctg gaactcatgc agtaccttcc tcagcacaca 1320
attgaaacgt acaggcaaca gcaacagcag cagcaccagc acttacttca gaaacatctc 1380
ctttcagcct gcttcaggaa tgagcttgtg gagccccgga gagaaactcc aaaacaatct 1440
gacgtcttct ttagacattc caagccccca aaccgatcag tgtacccata gagccctatc 1500
tctatatttt aagtgtgtgt gttgtatttc catgtgtata tgtgagtgtg tgtgtgtgta 1560
tgtgtgtgcg tgtgtatcta gccctcataa acaggacttg aagacacttt ggctcagaga 1620
cccaactgct caaaggcaca aagccactag tgagagaatc ttttgaaggg actcaaacct 1680
ttacaagaaa ggatgttttc tgcagatttt gtatccttag accggccatt ggtgggtgag 1740
gaaccactgt gtttgtctgt gagctttctg ttgtttcctg ggagggaggg gtcaggtggg 1800
gaaaggggca ttaagatgtt tattggaacc cttttctgtc ttcttctgtt gtttttctaa 1860
aattcacagg gaagcttttg agcaggtctc aaacttaaga tgtcttttta agaaaaggag 1920
aaaaaagttg ttattgtctg tgcataagta agttgtaggt gactgagaga ctcagtcaga 1980
cccttttaat gctggtcatg taataatatt gcaagtagta agaaacgaag gtgtcaagtg 2040
tactgctggg cagcgaggtg atcattacca aaagtaatca actttgtggg tggagagttc 2100
tttgtgagaa cttgcattat ttgtgtcctc ccctcatgtg taggtagaac atttcttaat 2160
gctgtgtacc tgcctctgcc actgtatgtt ggcatctgtt atgctaaagt ttttcttgta 2220
catgaaaccc tggaagacct actacaaaaa aactgttgtt tggcccccat agcaggtgaa 2280
ctcattttgt gcttttaata gaaagacaaa tccaccccag taatattgcc cttacgtagt 2340
tgtttaccat tattcaaagc tcaaaataga atttgaagcc ctctcacaaa atctgtgatt 2400
aatttgctta attagagctt ctatccctca agcctaccta ccataaaacc agccatatta 2460
ctgatactgt tcagtgcatt tagccaggag acttacgttt tgagtaagtg agatccaagc 2520
agacgtgtta aaatcagcac tcctggactg gaaattaaag attgaaaggg tagactactt 2580
ttcttttttt tactcaaaag tttagagaat ctctgtttct ttccatttta aaaacatatt 2640
ttaagataat agcataaaga ctttaaaaat gttcctcccc tccatcttcc cacacccagt 2700
caccagcact gtattttctg tcaccaagac aatgatttct tgttattgag gctgttgctt 2760
ttgtggatgt gtgattttaa ttttcaataa acttttgcat cttggtttaa aagaaa 2816
<210>65
<211>2816
<212>DNA
<213>人
<400>65
tcgttgatat caaagacagt tgaaggaaat gaattttgaa acttcacggt gtgccaccct 60
acagtactgc cctgaccctt acatccagcg tttcgtagaa acccagctca tttctcttgg 120
aaagaaagtt attaccgatc caccatgtcc cagagcacac agacaaatga attcctcagt 180
ccagaggttt tccagcatat ctgggatttt ctggaacagc ctatatgttc agttcagccc 240
attgacttga actttgtgga tgaaccatca gaagatggtg cgacaaacaa gattgagatt 300
agcatggact gtatccgcat gcaggactcg gacctgagtg accccatgtg gccacagtac 360
acgaacctgg ggctcctgaa cagcatggac cagcagattc agaacggctc ctcgtccacc 420
agtccctata acacagacca cgcgcagaac agcgtcacgg cgccctcgcc ctacgcacag 480
cccagctcca ccttcgatgc tctctctcca tcacccgcca tcccctccaa caccgactac 540
ccaggcccgc acagtttcga cgtgtccttc cagcagtcga gcaccgccaa gtcggccacc 600
tggacgtatt ccactgaact gaagaaactc tactgccaaa ttgcaaagac atgccccatc 660
cagatcaagg tgatgacccc acctcctcag ggagctgtta tccgcgccat gcctgtctac 720
aaaaaagctg agcacgtcac ggaggtggtg aagcggtgcc ccaaccatga gctgagccgt 780
gaattcaacg agggacagat tgcccctcct agtcatttga ttcgagtaga ggggaacagc 840
catgcccagt atgtagaaga tcccatcaca ggaagacaga gtgtgctggt accttatgag 900
ccaccccagg ttggcactga attcacgaca gtcttgtaca atttcatgtg taacagcagt 960
tgtgttggag ggatgaaccg ccgtccaatt ttaatcattg ttactctgga aaccagagat 1020
gggcaagtcc tgggccgacg ctgctttgag gcccggatct gtgcttgccc aggaagagac 1080
aggaaggcgg atgaagatag catcagaaag cagcaagttt cggacagtac aaagaacggt 1140
gatggtacga agcgcccgtt tcgtcagaac acacatggta tccagatgac atccatcaag 1200
aaacgaagat ccccagatga tgaactgtta tacttaccag tgaggggccg tgagacttat 1260
gaaatgctgt tgaagatcaa agagtccctg gaactcatgc agtaccttcc tcagcacaca 1320
attgaaacgt acaggcaaca gcaacagcag cagcaccagc acttacttca gaaacatctc 1380
ctttcagcct gcttcaggaa tgagcttgtg gagccccgga gagaaactcc aaaacaatct 1440
gacgtcttct ttagacattc caagccccca aaccgatcag tgtacccata gagccctatc 1500
tctatatttt aagtgtgtgt gttgtatttc catgtgtata tgtgagtgtg tgtgtgtgta 1560
tgtgtgtgcg tgtgtatcta gccctcataa acaggacttg aagacacttt ggctcagaga 1620
cccaactgct caaaggcaca aagccactag tgagagaatc ttttgaaggg actcaaacct 1680
ttacaagaaa ggatgttttc tgcagatttt gtatccttag accggccatt ggtgggtgag 1740
gaaccactgt gtttgtctgt gagctttctg ttgtttcctg ggagggaggg gtcaggtggg 1800
gaaaggggca ttaagatgtt tattggaacc cttttctgtc ttcttctgtt gtttttctaa 1860
aattcacagg gaagcttttg agcaggtctc aaacttaaga tgtcttttta agaaaaggag 1920
aaaaaagttg ttattgtctg tgcataagta agttgtaggt gactgagaga ctcagtcaga 1980
cccttttaat gctggtcatg taataatatt gcaagtagta agaaacgaag gtgtcaagtg 2040
tactgctggg cagcgaggtg atcattacca aaagtaatca actttgtggg tggagagttc 2100
tttgtgagaa cttgcattat ttgtgtcctc ccctcatgtg taggtagaac atttcttaat 2160
gctgtgtacc tgcctctgcc actgtatgtt ggcatctgtt atgctaaagt ttttcttgta 2220
catgaaaccc tggaagacct actacaaaaa aactgttgtt tggcccccat agcaggtgaa 2280
ctcattttgt gcttttaata gaaagacaaa tccaccccag taatattgcc cttacgtagt 2340
tgtttaccat tattcaaagc tcaaaataga atttgaagcc ctctcacaaa atctgtgatt 2400
aatttgctta attagagctt ctatccctca agcctaccta ccataaaacc agccatatta 2460
ctgatactgt tcagtgcatt tagccaggag acttacgttt tgagtaagtg agatccaagc 2520
agacgtgtta aaatcagcac tcctggactg gaaattaaag attgaaaggg tagactactt 2580
ttcttttttt tactcaaaag tttagagaat ctctgtttct ttccatttta aaaacatatt 2640
ttaagataat agcataaaga ctttaaaaat gttcctcccc tccatcttcc cacacccagt 2700
caccagcact gtattttctg tcaccaagac aatgatttct tgttattgag gctgttgctt 2760
ttgtggatgt gtgattttaa ttttcaataa acttttgcat cttggtttaa aagaaa 2816
<210>66
<211>5838
<212>DNA
<213>人
<400>66
ccgggcaggt ggctcatgct cgggagcgtg gttgagcggc tggcgcggtt gtcctggagc 60
aggggcgcag gaattctgat gtgaaactaa cagtctgtga gccctggaac ctccgctcag 120
agaagatgaa ggatatcgac ataggaaaag agtatatcat ccccagtcct gggtatagaa 180
gtgtgaggga gagaaccagc acttctggga cgcacagaga ccgtgaagat tccaagttca 240
ggagaactcg accgttggaa tgccaagatg ccttggaaac agcagcccga gccgagggcc 300
tctctcttga tgcctccatg cattctcagc tcagaatcct ggatgaggag catcccaagg 360
gaaagtacca tcatggcttg agtgctctga agcccatccg gactacttcc aaacaccagc 420
acccagtgga caatgctggg cttttttcct gtatgacttt ttcgtggctt tcttctctgg 480
cccgtgtggc ccacaagaag ggggagctct caatggaaga cgtgtggtct ctgtccaagc 540
acgagtcttc tgacgtgaac tgcagaagac tagagagact gtggcaagaa gagctgaatg 600
aagttgggcc agacgctgct tccctgcgaa gggttgtgtg gatcttctgc cgcaccaggc 660
tcatcctgtc catcgtgtgc ctgatgatca cgcagctggc tggcttcagt ggaccagcct 720
tcatggtgaa acacctcttg gagtataccc aggcaacaga gtctaacctg cagtacagct 780
tgttgttagt gctgggcctc ctcctgacgg aaatcgtgcg gtcttggtcg cttgcactga 840
cttgggcatt gaattaccga accggtgtcc gcttgcgggg ggccatccta accatggcat 900
ttaagaagat ccttaagtta aagaacatta aagagaaatc cctgggtgag ctcatcaaca 960
tttgctccaa cgatgggcag agaatgtttg aggcagcagc cgttggcagc ctgctggctg 1020
gaggacccgt tgttgccatc ttaggcatga tttataatgt aattattctg ggaccaacag 1080
gcttcctggg atcagctgtt tttatcctct tttacccagc aatgatgttt gcatcacggc 1140
tcacagcata tttcaggaga aaatgcgtgg ccgccacgga tgaacgtgtc cagaagatga 1200
atgaagttct tacttacatt aaatttatca aaatgtatgc ctgggtcaaa gcattttctc 1260
agagtgttca aaaaatccgc gaggaggagc gtcggatatt ggaaaaagcc gggtacttcc 1320
agggtatcac tgtgggtgtg gctcccattg tggtggtgat tgccagcgtg gtgaccttct 1380
ctgttcatat gaccctgggc ttcgatctga cagcagcaca ggctttcaca gtggtgacag 1440
tcttcaattc catgactttt gctttgaaag taacaccgtt ttcagtaaag tccctctcag 1500
aagcctcagt ggctgttgac agatttaaga gtttgtttct aatggaagag gttcacatga 1560
taaagaacaa accagccagt cctcacatca agatagagat gaaaaatgcc accttggcat 1620
gggactcctc ccactccagt atccagaact cgcccaagct gacccccaaa atgaaaaaag 1680
acaagagggc ttccaggggc aagaaagaga aggtgaggca gctgcagcgc actgagcatc 1740
aggcggtgct ggcagagcag aaaggccacc tcctcctgga cagtgacgag cggcccagtc 1800
ccgaagagga agaaggcaag cacatccacc tgggccacct gcgcttacag aggacactgc 1860
acagcatcga tctggagatc caagagggta aactggttgg aatctgcggc agtgtgggaa 1920
gtggaaaaac ctctctcatt tcagccattt taggccagat gacgcttcta gagggcagca 1980
ttgcaatcag tggaaccttc gcttatgtgg cccagcaggc ctggatcctc aatgctactc 2040
tgagagacaa catcctgttt gggaaggaat atgatgaaga aagatacaac tctgtgctga 2100
acagctgctg cctgaggcct gacctggcca ttcttcccag cagcgacctg acggagattg 2160
gagagcgagg agccaacctg agcggtgggc agcgccagag gatcagcctt gcccgggcct 2220
tgtatagtga caggagcatc tacatcctgg acgaccccct cagtgcctta gatgcccatg 2280
tgggcaacca catcttcaat agtgctatcc ggaaacatct caagtccaag acagttctgt 2340
ttgttaccca ccagttacag tacctggttg actgtgatga agtgatcttc atgaaagagg 2400
gctgtattac ggaaagaggc acccatgagg aactgatgaa tttaaatggt gactatgcta 2460
ccatttttaa taacctgttg ctgggagaga caccgccagt tgagatcaat tcaaaaaagg 2520
aaaccagtgg ttcacagaag aagtcacaag acaagggtcc taaaacagga tcagtaaaga 2580
aggaaaaagc agtaaagcca gaggaagggc agcttgtgca gctggaagag aaagggcagg 2640
gttcagtgcc ctggtcagta tatggtgtct acatccaggc tgctgggggc cccttggcat 2700
tcctggttat tatggccctt ttcatgctga atgtaggcag caccgccttc agcacctggt 2760
ggttgagtta ctggatcaag caaggaagcg ggaacaccac tgtgactcga gggaacgaga 2820
cctcggtgag tgacagcatg aaggacaatc ctcatatgca gtactatgcc agcatctacg 2880
ccctctccat ggcagtcatg ctgatcctga aagccattcg aggagttgtc tttgtcaagg 2940
gcacgctgcg agcttcctcc cggctgcatg acgagcttttccgaaggatc cttcgaagcc 3000
ctatgaagtt ttttgacacg acccccacag ggaggattct caacaggttt tccaaagaca 3060
tggatgaagt tgacgtgcgg ctgccgttcc aggccgagat gttcatccag aacgttatcc 3120
tggtgttctt ctgtgtggga atgatcgcag gagtcttccc gtggttcctt gtggcagtgg 3180
ggccccttgt catcctcttt tcagtcctgc acattgtctc cagggtcctg attcgggagc 3240
tgaagcgtct ggacaatatc acgcagtcac ctttcctctc ccacatcacg tccagcatac 3300
agggccttgc caccatccac gcctacaata aagggcagga gtttctgcac agataccagg 3360
agctgctgga tgacaaccaa gctccttttt ttttgtttac gtgtgcgatg cggtggctgg 3420
ctgtgcggct ggacctcatc agcatcgccc tcatcaccac cacggggctg atgatcgttc 3480
ttatgcacgg gcagattccc ccagcctatg cgggtctcgc catctcttat gctgtccagt 3540
taacggggct gttccagttt acggtcagac tggcatctga gacagaagct cgattcacct 3600
cggtggagag gatcaatcac tacattaaga ctctgtcctt ggaagcacct gccagaatta 3660
agaacaaggc tccctcccct gactggcccc aggagggaga ggtgaccttt gagaacgcag 3720
agatgaggta ccgagaaaac ctccctcttg tcctaaagaa agtatccttc acgatcaaac 3780
ctaaagagaa gattggcatt gtggggcgga caggatcagg gaagtcctcg ctggggatgg 3840
ccctcttccg tctggtggag ttatctggag gctgcatcaa gattgatgga gtgagaatca 3900
gtgatattgg ccttgccgac ctccgaagca aactctctat cattcctcaa gagccggtgc 3960
tgttcagtgg cactgtcaga tcaaatttgg accccttcaa ccagtacact gaagaccaga 4020
tttgggatgc cctggagagg acacacatga aagaatgtat tgctcagcta cctctgaaac 4080
ttgaatctga agtgatggag aatggggata acttctcagt gggggaacgg cagctcttgt 4140
gcatagctag agccctgctc cgccactgta agattctgat tttagatgaa gccacagctg 4200
ccatggacac agagacagac ttattgattc aagagaccat ccgagaagca tttgcagact 4260
gtaccatgct gaccattgcc catcgcctgc acacggttct aggctccgat aggattatgg 4320
tgctggccca gggacaggtg gtggagtttg acaccccatc ggtccttctg tccaacgaca 4380
gttcccgatt ctatgccatg tttgctgctg cagagaacaa ggtcgctgtc aagggctgac 4440
tcctccctgt tgacgaagtc tcttttcttt agagcattgc cattccctgc ctggggcggg 4500
cccctcatcg cgtcctccta ccgaaacctt gcctttctcg attttatctt tcgcacagca 4560
gttccggatt ggcttgtgtg tttcactttt agggagagtc atattttgat tattgtattt 4620
attccatatt catgtaaaca aaatttagtt tttgttctta attgcactct aaaaggttca 4680
gggaaccgtt attataattg tatcagaggc ctataatgaa gctttatacg tgtagctata 4740
tctatatata attctgtaca tagcctatat ttacagtgaa aatgtaagct gtttatttta 4800
tattaaaata agcactgtgc taataacagt gcatattcct ttctatcatt tttgtacagt 4860
ttgctgtact agagatctgg ttttgctatt agactgtagg aagagtagca tttcattctt 4920
ctctagctgg tggtttcacg gtgccaggtt ttctgggtgt ccaaaggaag acgtgtggca 4980
atagtgggcc ctccgacagc cccctctgcc gcctccccac agccgctcca ggggtggctg 5040
gagacgggtg ggcggctgga gaccatgcag agcgccgtga gttctcaggg ctcctgcctt 5100
ctgtcctggt gtcacttact gtttctgtca ggagagcagc ggggcgaagc ccaggcccct 5160
tttcactccc tccatcaaga atggggatca cagagacatt cctccgagcc ggggagtttc 5220
tttcctgcct tcttcttttt gctgttgttt ctaaacaaga atcagtctat ccacagagag 5280
tcccactgcc tcaggttcct atggctggcc actgcacaga gctctccagc tccaagacct 5340
gttggttcca agccctggag ccaactgctg ctttttgagg tggcactttt tcatttgcct 5400
attcccacac ctccacagtt cagtggcagg gctcaggatt tcgtgggtct gttttccttt 5460
ctcaccgcag tcgtcgcaca gtctctctct ctctctcccc tcaaagtctg caactttaag 5520
cagctcttgc taatcagtgt ctcacactgg cgtagaagtt tttgtactgt aaagagacct 5580
acctcaggtt gctggttgct gtgtggtttg gtgtgttccc gcaaaccccc tttgtgctgt 5640
ggggctggta gctcaggtgg gcgtggtcac tgctgtcatc agttgaatgg tcagcgttgc 5700
atgtcgtgac caactagaca ttctgtcgcc ttagcatgtt tgctgaacac cttgtggaag 5760
caaaaatctg aaaatgtgaa taaaattatt ttggattttg taaaaaaaaa aaaaaaaaaa 5820
aaaaaaaaaa aaaaaaaa 5838
<210>67
<211>1181
<212>DNA
<213>人
<400>67
ggcacgaggc ccgggccccc caaagtcccg gccgggccga gggtcggcgg ccgccggcgg 60
gccgggcccg cgcacagcgc ccgcatgtac aacatgatgg agacggagct gaagccgccg 120
ggcccgcagc aaacttcggg gggcggcggc ggcaactcca ccgcggcggc ggccggcggc 180
aaccagaaaa acagcccgga ccgcgtcaag cggcccatga atgccttcat ggtgtggtcc 240
cgcgggcagc ggcgcaagat ggcccaggag aaccccaaga tgcacaactc ggagatcagc 300
aagcgcctgg gcgccgagtg gaaacttttg tcggagacgg agaagcggcc gttcatcgac 360
gaggctaagc ggctgcgagc gctgcacatg aaggagcacc cggattataa ataccggccc 420
cggcggaaaa ccaagacgct catgaagaag gataagtaca cgctgcccgg cgggctgctg 480
gcccccggcg gcaatagcat ggcgagcggg gtcggggtgg gcgccggcct gggcgcgggc 540
gtgaaccagc gcatggacag ttacgcgcac atgaacggct ggagcaacgg cagctacagc 600
atgatgcagg accagctggg ctacccgcag cacccgggcc tcaatgcgca cggcgcagcg 660
cagatgcagc ccatgcaccg ctacgacgtg agcgccctgc agtacaactc catgaccagc 720
tcgcagacct acatgaacgg ctcgcccacc tacagcatgt cctactcgca gcagggcacc 780
cctggcatgg ctcttggctc catgggttcg gtggtcaagt ccgaggccag ctccagcccc 840
cctgtggtta cctcttcctc ccactccagg gcgccctgcc aggccgggga cctccgggac 900
atgatcagca tgtatctccc cggcgccgag gtgccggaac ccgccgcccc cagcagactt 960
cacatgtccc agcactacca gagcggcccg gtgcccggca cggccattaa cggcacactg 1020
cccctctcac acatgtgagg gccggacagc gaactggagg ggggagaaat tttcaaagaa 1080
aaacgaggga aatgggaggg gtgcaaaaga ggagagtaag aaacagcatg gagaaaaccc 1140
ggtacgctca aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a 1181
<210>68
<211>4755
<212>DNA
<213>人
<400>68
gctgctctcg ttcgcttggc tcagctcagc tcagctcagc gcagctccgc ggccgccaag 60
ccgaggcggg cacggtctcc gagtcgcgga cgccagctcc gagctccctc tctccgccgc 120
gcctccgcca ggtcgcgcct tcgtcgggac cacttcgggc aggagtcgcg tggcgaaggc 180
ctgcggccgc ggcacaaagt tgggggccgc gaagatgagg ctgtccccgg cgcccctgaa 240
gctgagccgg actccggcac tgctggccct ggcgctgccc ctggccgcgg cgctggcctt 300
ctccgacgag accctggaca aagtgcccaa gtcagagggc tactgcagcc gtatcctgcg 360
cgcccagggc acgcggcgcg agggctacac cgagttcagc ctccgcgtgg agggcgaccc 420
cgacttctac aagccgggaa ccagctaccg cgtaacactt tcagctgctc ctccctccta 480
cttcagagga ttcacattaa ttgccctcag agagaacaga gagggtgata aggaagaaga 540
ccatgctggg accttccaga tcatagacga agaagaaact cagtttatga gcaattgccc 600
tgttgcagtc actgaaagca ctccacggag gaggacccgg atccaggtgt tttggatagc 660
accaccagcg ggaacaggct gcgtgattct gaaggccagc atcgtacaaa aacgcattat 720
ttattttcaa gatgagggct ctctgaccaa gaaactttgt gaacaagatt ccacatttga 780
tggggtgact gacaaaccca tcttagactg ctgtgcctgc ggaactgcca agtacagact 840
cacattttat gggaattggt ccgagaagac acacccaaag gattaccctc gtcgggccaa 900
ccactggtct gcgatcatcg gaggatccca ctccaagaat tatgtactgt gggaatatgg 960
aggatatgcc agcgaaggcg tcaaacaagt tgcagaattg ggctcacccg tgaaaatgga 1020
ggaagaaatt cgacaacaga gtgatgaggt cctcaccgtc atcaaagcca aagcccagtg 1080
gccagcctgg cagcctctca acgtgagagc agcaccttca gctgaatttt ccgtggacag 1140
aacgcgccat ttaatgtcct tcctgaccat gatgggccct agtcccgact ggaacgtagg 1200
cttatctgca gaagatctgt gcaccaagga atgtggctgg gtccagaagg tggtgcaaga 1260
cctgattccc tgggacgctg gcaccgacag cggggtgacc tatgagtcac ccaacaaacc 1320
caccattccc caggagaaaa tccggcccct gaccagcctg gaccatcctc agagtccttt 1380
ctatgaccca gagggtgggt ccatcactca agtagccaga gttgtcatcg agagaatcgc 1440
acggaagggt gaacaatgca atattgtacc tgacaatgtc gatgatattg tagctgacct 1500
ggctccagaa gagaaagatg aagatgacac ccctgaaacc tgcatctact ccaactggtc 1560
cccatggtcc gcctgcagct cctccacctg tgacaaaggc aagaggatgc gacagcgcat 1620
gctgaaagca cagctggacc tcagcgtccc ctgccctgac acccaggact tccagccctg 1680
catgggccct ggctgcagtg acgaagacgg ccccacctgc accatgtccg agtggatcac 1740
ctggtcgccc tgcagcatct cctgcggcat gggcatgagg tcccgggaga ggtatgtgaa 1800
gcagttcccg gaggacggct ccgtgtgcac gctgcccact gaggaaacgg agaagtgcac 1860
ggtcaacgag gagtgctctc ccagcagctg cctgatgacc gagtggggcg agtgggacga 1920
gtacagcgcc acctgcggca tgggcatgaa gaagcggcac cgcatgatca agatgaaccc 1980
cgcagatggc tccatgtgca aagccgagac atcacaggca gagaagcgca tgatgccaga 2040
gtgccacacc atcccatgct tgctgtcccc atggtccgag tggagtgact gcagcgtgac 2100
ctgcgggaag ggcatgcgaa cccgacagcg gatgctcaag tctctggcag aacttggaga 2160
ctgcaatgag gatctggagc aggtggagaa gtgcatgctc cctgaatgcc ccattgactg 2220
tgagctcacc gagtggtccc agtggtcgga atgtaacaag tcatgtggga aaggccacgt 2280
gattcgaacc cggatgatcc aaatggagcc tcagtttgga ggtgcaccct gcccagagac 2340
tgtgcagcga aaaaagtgcc gcatccgaaa atgccttcga aatccatcca tccaaaagct 2400
acgctggagg gaggcccgag agagccggcg gagtgagcag ctgaaggaag agtctgaagg 2460
ggagcagttc ccaggttgta ggatgcgccc atggacggcc tggtcagaat gcaccaaact 2520
gtgcggaggt ggaattcagg aacgttacat gactgtaaag aagagattca aaagctccca 2580
gtttaccagc tgcaaagaca agaaggagat cagagcatgc aatgttcatc cttgttagca 2640
agggtacgag ttccccaggg ctgcactcta gattccagag tcaccaatgg ctggattatt 2700
tgcttgttta agacaattta aattgtgtac gctagttttc atttttgcag tgtggttcgc 2760
ccagtagtct tgtggatgcc agagacatcc tttctgaata cttcttgatg ggtacaggct 2820
gagtggggcg ccctcacctc cagccagcct cttcctgcag aggagtagtg tcagccacct 2880
tgtactaagc tgaaacatgt ccctctggag cttccacctg gccagggagg acggagactt 2940
tgacctactc cacatggaga ggcaaccatg tctggaagtg actatgcctg agtcccaggg 3000
tgcggcaggt aggaaacatt cacagatgaa gacagcagat tccccacatt ctcatctttg 3060
gcctgttcaa tgaaaccatt gtttgcccat ctcttcttag tggaacttta ggtctctttt 3120
caagtctcct cagtcatcaa tagttcctgg ggaaaaacag agctggtaga cttgaagagg 3180
agcattgatg ttgggtggct tttgttcttt cactgagaaa ttcggaatac atttgtctca 3240
cccctgatat tggttcctga tgccccccca acaaaaataa ataaataaat tatggctgct 3300
ttatttaaat ataaggtagc tagtttttac acctgagata aataataagc ttagagtgta 3360
tttttccctt gcttttgggg gttcagagga gtatgtacaa ttcttctggg aagccagcct 3420
tctgaacttt ttggtactaa atccttattg gaaccaagac aaaggaagca aaattggtct 3480
ctttagagac caatttgcct aaattttaaa atcttcctac acacatctag acgttcaagt 3540
ttgcaaatca gtttttagca agaaaacatt tttgctatac aaacattttg ctaagtctgc 3600
ccaaagcccc cccaatgcat tccttcaaca aaatacaatc tctgtacttt aaagttattt 3660
tagtcatgaa attttatatg cagagagaaa aagttaccga gacagaaaac aaatctaagg 3720
gaaaggaata ttatgggatt aagctgagca agcaattctg gtggaaagtc aaacctgtca 3780
gtgctccaca ccagggctgt ggtcctccca gacatgcata ggaatggcca caggtttaca 3840
ctgccttccc agcaattata agcacaccag attcagggag actgaccacc aagggatagt 3900
gtaaaaggac attttctcag ttgggtccat cagcagtttt tcttcctgca tttattgttg 3960
aaaactattg tttcatttct tcttttatag gccttattac tgcttaatcc aaatgtgtac 4020
cattggtgag acacatacaa tgctctgaat acactacgaa tttgtattaa acacatcaga 4080
atatttccaa atacaacata gtatagtcct gaatatgtac ttttaacaca agagagacta 4140
ttcaataaaa actcactggg tctttcatgt ctttaagcta agtaagtgtt cagaaggttc 4200
ttttttatat tgtcctccac ctccatcatt ttcaataaaa gatagggctt ttgctccctt 4260
gttcttggag ggaccattat tacatctctg aactaccttt gtatccaaca tgttttaaat 4320
ccttaaatga attgctttct cccaaaaaaa gcacagtata aagaaacaca agatttaatt 4380
atttttctac ttggggggaa aaaagtcctc atgtagaagc acccactttt gcaatgttgt 4440
tctaagctat ctatctaact ctcagcccat gataaagttc cttaagctgg tgattcctaa 4500
tcaaggacaa gccaccctag tgtctcatgt ttgtatttgg tcccagttgg gtacatttta 4560
aaatcctgat tttggagact taaaaccagg ttaatggcta agaatgggta acatgactct 4620
tgttggattg ttattttttg tttgcaatgg ggaatttata agaagcatca agtctctttc 4680
ttaccaaagt cttgttaggt ggtttatagt tcttttggct aacaaatcat tttggaaata 4740
aagatttttt actac 4755
<210>69
<211>6841
<212>DNA
<213>人
<400>69
gccggagggc gcccgagggg ccccgggccg cggcgctcag ggcccgggcg gccggcggcg 60
gccccggggc tggggggagt ccagcccgga tattgagtgc agccattgag aaaagccaaa 120
ctcttgtgtg tgcgcgtctc gatagccccc aagatggccg ccaatgtggg atcgatgttt 180
caatattgga agcgatttga tctacggcga ctccagaagg agcttaattc cgtcgcttct 240
gagctgtctg cacggcagga ggagagtgaa cattctcata aacatttaat tgaactccgc 300
cgggaattta agaaaaatgt acctgaggaa atcagagaga tggtggctcc tgtattaaaa 360
agcttccaag ccgaggtggt ggcccttagt aagagaagtc aggaggcgga ggctgctttt 420
ctgagtgttt acaagcaatt aattgaagca ccagaccccg tgcctgtgtt tgaggcggca 480
cgcagcctag acgacagact gcagcccccc agctttgacc ccagtgggca gccccggcga 540
gacctccaca cttcgtggaa gaggaacccc gagctcctca gccccaaaga gcagagagag 600
gggacgtcgc ctgccgggcc cacgctgacc gagggaagcc gcctcccagg cattcccggg 660
aaagccctcc tgacagaaac cttgctgcag agaaatgagg cggaaaaaca aaagggcctt 720
caagaagtac agatcacttt ggcggccaga ctgggggagg cagaggagaa aatcaaagtc 780
ctacattcag cgctaaaggc tacgcaggca gagctgctag agctgcggcg gaagtacgac 840
gaggaggcag catccaaggc agatgaagtc ggcctgatca tgaccaacct ggagaaagct 900
aatcagcgag ctgaggctgc ccagcgggag gtggaaagtc tccgggaaca gctggcctct 960
gtcaacagct ccatccgcct ggcttgctgc tctccccagg ggcccagtgg ggataaggtg 1020
aacttcactc tgtgctcggg ccctcggctg gaggccgcgc tggcctccaa ggacagggag 1080
atcctgcggc tgctgaagga cgtgcagcac ctccagagct cactgcagga gctggaggag 1140
gcatccgcca accagatcgc cgacctggag cggcagctca cggccaagtc cgaggccata 1200
gaaaagctgg aagagaagct ccaggcccag tctgactatg aggaaattaa aacggagctg 1260
agcatcctga aagccatgaa gctggcctcc agcacctgca gcctccccca gggcatggcc 1320
aagcctgaag actcactgct tattgcaaag gaggccttct tccccacgca gaaattcctt 1380
ctggagaagc ccagcctcct ggccagccct gaggaagacc catcagagga cgattccatc 1440
aaggattcac tgggcacgga gcagtcctac ccctcccctc agcagctccc acctccacca 1500
gggccagaag accccctgtc tcccagcccc gggcagcccc tgctgggccc cagcttgggg 1560
cctgacggca ctcggacttt ctcgctgtcc cccttcccca gcctggcatc aggggagaga 1620
ctgatgatgc ccccagccgc cttcaaggga gaggcgggcg gcctgctggt gttcccccca 1680
gccttctatg gcgccaagcc ccccacagcc cctgccaccc cggcccctgg ccctgagcca 1740
ctgggcggtc ctgagcccgc ggatggtggt gggggcggag cggcggggcc cggggcagag 1800
gaggagcagc tggacacggc agagatcgcc ttccaggtga aggagcagct gctgaaacac 1860
aacatcgggc agcgggtgtt tgggcattac gtgctggggc tgtcgcaggg ctcggtcagc 1920
gagatcctag cccggcccaa gccctggcgc aagctcacgg tgaagggcaa ggagcccttc 1980
atcaagatga agcagttcct gtcggatgag cagaatgtac tggcgctcag gaccatccaa 2040
gtgcggcagc gaggcagcat caccccgaga atccgcacgc ctgagacagg ctcagacgac 2100
gccatcaaga gcattctaga gcaggccaag aaggagatcg agtcgcagaa gggcggcgag 2160
cccaagacct cggtggcccc gctgagcatc gccaacggca cgacccccgc cagcacctcg 2220
gaggacgcca tcaagagcat cctggagcag gcacgccgtg agatgcaggc gcaacagcag 2280
gcgctgctgg agatggaggt ggcgcccagg ggccgctcgg tgcccccctc gcccccggag 2340
cggccatcac tggccaccgc gagccagaac ggggccccgg ccttggtgaa gcaggaggag 2400
ggcagcgggg gccccgcgca ggcgccgctc ccggtcctgt cccccgccgc cttcgtgcag 2460
agcatcatcc gcaaggtcaa gtccgagatc ggcgacgccg gctacttcga ccaccactgg 2520
gcctccgacc gcggcctgct cagccgcccc tacgcctccg tgtcgccctc gctgtcctcc 2580
tcctcctcct ctggctactc tggccagccc aacggccgcg cctggccccg cggggacgag 2640
gcccctgtgc cccccgagga cgaggcggcg gcaggggcgg aggacgaacc ccccaggacg 2700
ggcgagctca aggctgaggg cgcgacggcc gaggcgggcg cgcggctgcc ctactacccg 2760
gcctacgtgc cgcgcaccct gaagcccacc gtgccgccgc tgacccccga gcagtacgag 2820
ctgtacatgt accgtgaggt agacacgctg gagctcaccc gccaggtcaa ggagaagctg 2880
gccaagaacg gcatctgcca gaggatcttc ggggagaagg tgctgggcct gtcacagggc 2940
agcgtgagcg acatgctgtc ccggccgaag ccatggagca agctgacgca gaaggggcgg 3000
gagcccttca tccgcatgca gctgtggctc tctgaccagc tcggccaggc agtgggccag 3060
cagcctggtg cctcccaggc cagtcccaca gaaccaaggt cctcaccatc cccacccccc 3120
agccccacag agcctgagaa gagctcccag gagccgttga gcctgtccct ggagagcagc 3180
aaggagaacc agcagccaga gggccgctcc agctcctcgt tgagcgggaa gatgtactca 3240
ggcagccagg ccccaggggg catccaggag atcgtggcca tgtcccccga gctggacacg 3300
tactccatca ccaagagggt gaaggaggtc ctcacagaca acaatctagg gcagcggctg 3360
tttggggaaa gcatcctggg tctgacacag ggctccgtgt ctgacctgct gtcccggccc 3420
aaaccctggc acaagctgag cctgaagggg cgggagcctt ttgtccgcat gcagctgtgg 3480
ctcaatgacc cccataacgt ggagaagctg agggatatga agaagctgga gaagaaagcc 3540
tacctgaaac gtcgctatgg cctcatcagc accggctcag acagtgagtc cccggccacc 3600
cgctcagagt gccccagccc ctgcctgcag ccccaggacc tgagcctcct gcagatcaag 3660
aagccccggg tggtgctggc acccgaggag aaggaggcac tgcggaaggc ctatcagctg 3720
gaaccctacc cctcgcagca gaccatcgag ctcctctcct tccagctcaa cctcaagacc 3780
aacaccgtca tcaactggtt ccacaactac aggtcccgga tgcgccggga gatgttggtg 3840
gaggggaccc aggatgagcc agaccttgat ccaagcgggg gtcctggaat cctaccgcca 3900
ggccactccc acccagaccc caccccgcag agccctgact ctgagactga ggaccagaag 3960
ccaaccgtga aggaactgga gcttcaggag ggccctgagg agaacagcac acccctgacc 4020
acccaggaca aggcccaagt gaggatcaag caggaacaga tggaggagga tgctgaggaa 4080
gaggcaggca gccagcccca ggactcaggg gagctggaca aaggccaagg tccccccaaa 4140
gaggagcatc ccgaccctcc gggtaatgat ggactcccaa aagtggctcc cgggcccctc 4200
cttccaggtg gatccacccc agactgtccc tcacttcatc cccaacagga gagtgaggcc 4260
ggggagcgac ttcacccgga ccctttaagt tttaagtcag cctcagagtc ctcacgctgc 4320
agcctggagg tgtcactgaa ctcgccctcg gccgcctcct caccaggcct catgatgtct 4380
gtgtcacctg tcccctcctc ctcagctccc atctccccat ccccacctgg cgccccccct 4440
gccaaagtgc cgagtgccag ccccactgct gacatggctg gagccttgca ccccagtgcc 4500
aaggtgaacc ccaacttgca gcggcggcat gagaagatgg ccaatctgaa caacatcatt 4560
taccgactag agcgggctgc caatcgggag gaggccctgg agtgggagtt ctgaaggcag 4620
ggtgaggggg caagggacat accctggtaa ctaccttcct tctcgcactt actctcctca 4680
acaggatggg gtaagggagg gaggaactca accatcaaaa tgtggacagc aatgttatgc 4740
cgtttacgtt ttttgttgta atcctagttc tatgaagctg tgtgagcagg tgggtcaaat 4800
gccattgcct ccacttttct gcacccccct gctcctcttc accctgaccc ctctgcagga 4860
ggcagaagca aaatggcacc acatattcac ctgaaaactc caaactcttt tagaaaaata 4920
aataaatatt tatagacctc ttttagatat tttaataaag gatcctttgg aatttatccc 4980
agctgatgct gttttgatat tacagagagt tataaaatca ggatgctgtc acaactgttg 5040
cgaagtatac actgaagttg tgtcgttttt gccactagat gagattaaaa gaagacaatt 5100
attcaaagcc atcacaaaac actataagac tgaccaaaat ttagataacc tttgaaccac 5160
gatttttttc cacatctgtc tgtgagacac agcgcaatgc tactgccctt ccagaaactg 5220
tgctaaaaag agaaagtcca aaagactcta aacaaaaacc tcgacgccgt tgaggatgtg 5280
tttcattctg gtggtctgtt ttgcaagctt gataacagaa tgtccgtgcc attgtaaatg 5340
ttgtagagat gtgggccgtg gcccaaccgt cctatatgag atgtagcatg gtacagaaca 5400
aactgcttac acaggtctca ctagttagaa acctgtgggc catggaggtc agacatccat 5460
cttgtccatc tataggcaag aagtgtttcc agatcctttg gaaaggtggg catggggcag 5520
gtgcttggag agtggcgttt gagccagagc gaccccattt cccgtgtgaa ccataggcac 5580
aacccaggaa gtttccccac ttgtaggagt gtgggtattc cagagcaaga ctgtggccac 5640
catcttcccc tcttggtgtt ttccgaaagt gacagtgttg gtcatcccat gaccactgaa 5700
gcttagtaac cagcgccaaa aagtagattc atcaaactag agaccccagc tccccttctc 5760
gccatcttct ttctcaagtt gaccgtggtg ctgtttctgg aaggcatctg caactccaag 5820
tccatgcaga actctggaag gccaagttca tcgcagcatg ttcaccatat cccagcctcc 5880
aaatctatcc tcctaccttc caacgcatga cctgttgggg agcagagact taacccccaa 5940
ctcagaggaa cccttcctcc agcgtctttg gcatggtttc tagggtgaga gttcccaatt 6000
tggatagaac ggccaccata ttggttactg aatctctctc ccttgttttt attacgtttc 6060
ctttttcaaa ctgtccatgg gaaggctgaa ttgagtgact ccccagaatg aagatgagaa 6120
ggtgaatata atcaatgcca atgtaatgcc agcgggtgag atggccgatg gaggtttcaa 6180
agatgtagct agcattttga aaccatatgg gcaaaacccg gcaaccagaa ggggacagat 6240
aaggaccgtt ccagaaatcc caactctcac acccagccca ggctgcagtc tccacaccaa 6300
acagtcaaca aaacacaaac cctgaaggaa aaccttttcc atacacccag gctatgcatt 6360
gaagagtttt ccactgtata catttttatc cagatgaagg tatttttata ttttgacaat 6420
aggaaacagt gaccattttc agagtaatca aatctggaac aaatgaaaca tcttttagcc 6480
accaccaccc tgttgcaatt aagacaaccg tgggggaaca caccactttt tactgttgaa 6540
accaacacaa cgttgaaatc caggcttata cgcagactcc gattcctaga gaactaaatt 6600
tggctttagt gtgacgggat ttgattaagc acttagtata gtcttttgaa cacggaaatc 6660
ctgttgtact taaagctagc ggacccgtga acaactttgt caggttcacg tcctataacg 6720
gttaaaaaac acacacacac atacacaaac cgtttctatg agagattgat gaactttgtt 6780
taaaatttta aaaaaaggaa cacgttctgt aaacgagtcg ctaaatacag aattgtataa 6840
t 6841
<210>70
<211>443
<212>DNA
<213>人
<400>70
tttttttttt tttttccatt aacccaacac aagtttattt actaagtcaa gtcaaactga 60
ggagtatttg tttctttggt agttggtaga caaagaatac atatacatat tctatttccc 120
attaagcatt cgatcatgtt acaaaacaat ggcctagaga actatcattg aagatttacc 180
aaatctgcct gaagcaaaat gtgataaact gcagaaatgg tggagaatga cactggaagt 240
cataaagttg attctcaaac acgggtttga actgcatagg accgcttata tgcatatttt 300
gataaatata ttgaaaattt ttttggaaat ttgcaacaat ttaaaaaact tgcagatgca 360
ccatgtagct tagaaatact gaaaaactaa gaaaaaggtg tgtcatgaat tcatataata 420
tatgtagaca ctagtctatt tta 443
<210>71
<211>2432
<212>DNA
<213>人
<400>71
ggcgagtggc gagtggcgag tgtcaggggg gcggccggcg ggggcggggc ggccggagga 60
ggcgttggca gcgggctcgg acccacgcgg cgccgcggcc cgcctggcct gcagcgctcc 120
cacccccggc ggcggcacga tgccctttga cttcaggagg tttgacatct acaggaaggt 180
gcccaaggac cttacgcagc caacgtacac cggggccatt atctccatct gctgctgcct 240
cttcatcctc ttcctcttcc tctcggagct caccggattt ataacgacag aagttgtgaa 300
cgagctctat gtcgatgacc cagacaagga cagcggtggc aagatcgacg tcagtctgaa 360
catcagttta cccaatctgc actgcgagtt ggttgggctt gacattcagg atgagatggg 420
caggcacgaa gtgggccaca tcgacaactc catgaagatc ccgctgaaca atggggcagg 480
ctgccgcttc gaggggcagt tcagcatcaa caaggtcccc ggcaacttcc acgtgtccac 540
acacagtgcc acagcccagc cacagaaccc agacatgacg catgtcatcc acaagctctc 600
ctttggggac acgctacagg tccagaacat ccacggagct ttcaatgctc tcgggggagc 660
agacagactc acctccaacc ccctggcctc ccacgactac atcctgaaga ttgtgcccac 720
ggtttatgag gacaagagtg gcaagcagcg gtactcctac cagtacacgg tggccaacaa 780
ggaatacgtc gcctacagcc acacgggccg catcatccct gcaatctggt tccgctacga 840
cctcagcccc atcacggtca agtacacaga gagacggcag ccgctgtaca gattcatcac 900
cacgatctgt gccatcattg gcgggacctt caccgtcgcc ggcatcctgg actcatgcat 960
cttcacagcc tctgaggcct ggaagaagat ccagctgggc aagatgcatt gacgccacac 1020
ccagcctaat ggccgaggac cctgggcatc gccagccttg cctccagtgc cctgtctcct 1080
ttggccctca atctggtccc aaatctggct gtgtcccaaa gggtgtgtgg gaagtggggg 1140
gaaagtagag gatggctcga tgttttgcag ctacctcttt tccccgtgtt tctttttaga 1200
caaattacac tgcctgaagt tgcagttccc ctttccctgg ggagccccaa gaacagagtc 1260
aggcaagggg tggggagtcc agggatcttg gggacccctc ctaggagagc tgcagtctct 1320
tccctcaggg gaacatccca gaatgcatat cgatcagctc tcagccaggc ttcgacaatc 1380
tcgcagcccc cactaggtgg acacattaat gatttggttt ctcccctggg cagccaacct 1440
gccccagagg caccagacct gggctttcag ctttgggacc aggctgccca aaggtactcc 1500
tttatacacc cggcaccttc cacgaaagat ggtacttccc aagcaagccc ctatgatttg 1560
tcactataga tggaaccctg acttctgccc catcccttcc tgcccaacct agaacccagg 1620
cctcaagtct ttaccccacc cctttcttgt tcttccaaga agcagatgcc cagttgctca 1680
gcagcagcgg tagagacttg aatctgccca ccagtcacaa ggcgggtcac agattcctct 1740
tcctctcttc tcctcgttcc tctgaaccct ccaccaatgt gcctcagcct gtgtgctgtg 1800
tggcaacagc attctggttc ccactgccaa gatctcccac cactctgctg ggatctgcag 1860
tggcagggag tgggggttgt gtaaagggga agtcatcttt tgagatccag atagacatgg 1920
tttgtgcact tacgtccaga tgggaagcat ccttcctgca accctaaaat aatcatgcag 1980
cctctcagac ggacgccatc ggtcccaagg ccttaggtgg aggaagcaaa gcaggccagg 2040
cctgtcctgt ccgtggacct ctaccttctg gactccctac gggtgcagag cacttgggtt 2100
tctctacagc catcgtggcc cacttgacac tgtgctcctc catcagctgg tcacatgcca 2160
acacgttccc agcccctgag gcagctccag ggtgccccac ctgctcctga ggtgggtccc 2220
taccctgctg ctcctcttca tcctttccct tttgtcctga aagggaggag caatggtcca 2280
ggcattaatt ccacccaggg aattttagct atgccctcat gtcccaggga gagagccaca 2340
cgcctgtttt ccatttatag caagattgtt tgcatacttt tgtaatgaag gggagtgtcc 2400
agtggaagga tttttaaaat tatcttatgg at 2432
<210>72
<211>2782
<212>DNA
<213>人
<400>72
gcggccgcgg cggggcggcg cgggaaccgg gccccggggg gagtcggccg ggctgctgct 60
gctgctgctc caggtgctgc cgcccggggc tacggcaggg ccgggacgcc ggggcacgcg 120
gggcgctggc ggcggcggcg tctgctggcc cggcgcggcc ccagcctttc cccgggacgc 180
gcggctgctg ctgctcctgc cgccgctgcc gccactgtcg ccgccgccgc cgagctccgc 240
gcccgcagcc tccgcctccc ggatggacgc tctgccccgc agcgggctga acctgaagga 300
ggagccgctg ctgcccgccg gcctgggctc agtgcgctcc tggatgcagg gcgcgggcat 360
cctggacgcc agcaccgcgg cgcagagtgg cgtgggtctg gcacgagcac attttgagaa 420
gcagcctccc tccaacctca ggaaatccaa cttcttccac ttcgtgctgg ccatgtacga 480
ccggcagggg cagcccgtgg aggtggagcg cacagccttc atcgacttcg tggaaaagga 540
ccgagagccc ggggcggaaa agactaacaa tgggatccat taccgcctcc ggctggtgta 600
taacaatgga ctgcggacag agcaagacct ctacgtgcgt ctcatcgact ccatgtccaa 660
acaggccatc atctatgagg ggcaggacaa gaaccccgaa atgtgccgag tgctgctcac 720
ccatgagatc atgtgcagcc ggtgctgtga ccggaagagc tgtggcaacc ggaatgagac 780
gccctcagac cccgtcatca ttgacaggtt cttcctcaag ttcttcctca aatgcaacca 840
gaactgcctg aagaatgcgg ggaatcccag agacatgcgc cgcttccagg tggtggtgtc 900
cacgacggtg agcgtggacg gacacgtgct ggccgtgtcc gacaacatgt ttgtgcacaa 960
caactccaag catggccgca gggcgcgccg cctggacccc tccgaagctg ccaccccctg 1020
catcaaggcc atcagccccg gggagggctg gaccacgggc ggcgccaccg tcattgtcat 1080
cggcgacaac ttcttcgacg ggttgcaggt cgtgttcgga aacgtgctcg tgtggagcga 1140
gctcatcacg ccccacgcca tccgggtgca gacgcccccg cggcacatcc ccggggtggt 1200
ggaggtgacc ctctcctaca agtccaagca gttttgcaag ggatgccccg gccgctttgt 1260
ctacacagct ctgaacgagc ccaccattga ctacggattc cagaggctac agaaagtcat 1320
tcccagacac cccggagacc ccgagaggct gcccaaggaa gtgctgctga agcgggcggc 1380
cgacttggca gaagccctgt acggagtgcc cggcagtaac caggagctgc tcctgaagcg 1440
cgcggcggac gtggccgagg ctctgtacag caccccccgc gcacccgggc cgctcgcacc 1500
cctggccccg agccacccac actccgccgt cgtgggcatc aacgccttca gcagcccgct 1560
ggccatcgcc gtcggggacg ccaccccggg gcccgagccg ggctacgcgc gcagctgcag 1620
cagcgcgtcc ccccgcgggt tcgcgcccag ccccggctcg cagcagagcg gctacggcgg 1680
cggcctcgga gctggcctgg gcggctacgg cgcgccgggc gtggccggcc tcggcgtgcc 1740
tgggtccccc agcttcctca atggctccac cgccacctcg cccttcgcca aggagcgcct 1800
tcgcccccgt gctgcgcccc ccaagctccc caccccaggc ctgccccaga gcccacggag 1860
aggggcttcc agaccagtct tttgaggatt ctgacaagtt ccactctcca gcccgggggc 1920
ttcagggcct ggcatactcc taattacggt ctgcagctgt tcccatggag cccggactgg 1980
aggtccctct gggattcaca gccacacccc ggatggtggc acagacagat gcagggccag 2040
ggccatgggc ggacctcaac ccgtgagctg aacggggaga ggccttcacc ccatgctcaa 2100
gcctccccgc tagcagcccc acaggcttct ctcgcctccc tgtcttgggg tagtcagaag 2160
ccccagcact gtgcagatgc tcttggcagg acagcatcgc agggaggtgc tgggattctg 2220
ggcctcactg tctgggtctt ggttcctctg aaagagatgg atcttgtgca gaccagggtt 2280
gttgagtgag gggagcgtgg gatggggacc gtgggaaaga ggacagctca gggagaagtg 2340
acctggaaag gtcctgtttg catctgaccc atctcaactg gcccagcatc ccaacttctc 2400
tgcagcgaaa gggtggcgcc ccgcagcctc gggaggcctg cccaggctcc cgtggagctt 2460
ccaacagctg cttggccccg cagctgcccc cacttccttt gagacctgca ctctcatgct 2520
tgccgcatca tgcctccctg tgggggcttt gggcatggag gaggcagaag agggggtgcc 2580
aggcctcctg tatttggggt cttcccccag tggatgtctc atggactctg gccccacaca 2640
ctcacaatga ctctggctgg ccccacgcag cgggcccagc cgccccccag gtggcctcac 2700
attctgctct gctaagtttg gagaaaacag aacaataaac cagatgcagg tggtgcccgc 2760
ccggcctctc acctgcctcc tt 2782
<210>73
<211>1722
<212>DNA
<213>人
<400>73
ggggaaaaga gctaggaaag agctgcaaag cagtgtgggc tttttccctt tttttgctcc 60
ttttcattac ccctcctccg ttttcaccct tctccggact tcgcgtagaa cctgcgaatt 120
tcgaagagga ggtggcaaag tgggagaaaa gaggtgttag ggtttggggt ttttttgttt 180
ttgtttttgt tttttaattt cttgatttca acattttctc ccaccctctc ggctgcagcc 240
aacgcctctt acctgttctg cggcgccgcg caccgctggc agctgagggt tagaaagcgg 300
ggtgtatttt agattttaag caaaaatttt aaagataaat ccatttttct ctcccacccc 360
caacgccatc tccactgcat ccgatctcat tatttcggtg gttgcttggg ggtgaacaat 420
tttgtggctt tttttcccct ataattctga cccgctcagg cttgagggtt tctccggcct 480
ccgctcactg cgtgcacctg gcgctgccct gcttccccca acctgttgca aggctttaat 540
tcttgcaact gggacctgct cgcaggcacc ccagccctcc acctctctct acatttttgc 600
aagtgtctgg gggagggcac ctgctctacc tgccagaaat tttaaaacaa aaacaaaaac 660
aaaaaaatct ccgggggccc tcttggcccc tttatccctg cactctcgct ctcctgcccc 720
accccgaggt aaagggggcg actaagagaa gatggtgttg ctcaccgcgg tcctcctgct 780
gctggccgcc tatgcggggc cggcccagag cctgggctcc ttcgtgcact gcgagccctg 840
cgacgagaaa gccctctcca tgtgcccccc cagccccctg ggctgcgagc tggtcaagga 900
gccgggctgc ggctgctgca tgacctgcgc cctggccgag gggcagtcgt gcggcgtcta 960
caccgagcgc tgcgcccagg ggctgcgctg cctcccccgg caggacgagg agaagccgct 1020
gcacgccctg ctgcacggcc gcggggtttg cctcaacgaa aagagctacc gcgagcaagt 1080
caagatcgag agagactccc gtgagcacga ggagcccacc acctctgaga tggccgagga 1140
gacctactcc cccaagatct tccggcccaa acacacccgc atctccgagc tgaaggctga 1200
agcagtgaag aaggaccgca gaaagaagct gacccagtcc aagtttgtcg ggggagccga 1260
gaacactgcc cacccccgga tcatctctgc acctgagatg agacaggagtctgagcaggg 1320
cccctgccgc agacacatgg aggcttccct gcaggagctc aaagccagcc cacgcatggt 1380
gccccgtgct gtgtacctgc ccaattgtga ccgcaaagga ttctacaaga gaaagcagtg 1440
caaaccttcc cgtggccgca agcgtggcat ctgctggtgc gtggacaagt acgggatgaa 1500
gctgccaggc atggagtacg ttgacgggga ctttcagtgc cacaccttcg acagcagcaa 1560
cgttgagtga tgcgtccccc cccaaccttt ccctcacccc ctcccacccc cagccccgac 1620
tccagccagc gcctccctcc accccaggac gccactcatt tcatctcatt taagggaaaa 1680
atatatatct atctatttga ggaaaaaaaa aaaaaaaaaa aa 1722
<210>74
<211>2626
<212>DNA
<213>人
<400>74
gggtacggct gcgagaagac gacagaaggg gatgtcacct gctttatttc tggctttggc 60
ctgtggtctg tgatacccat cctgcttgat gttctgcaga atggcacttg actgctgggc 120
atgcatgaag ttaagggcaa gaaacagtat gccatgtgtt ctgtaccatc atgtgtctct 180
tcttgcttct gggcccttct actggtgaac tttcatcaag atctgcgcca tgccgtgtca 240
ctatcaagcc attaagtttt gtctgggttg ctgtcagccc cagttggctt cctggtcaac 300
aaggacctca agaactgcct gtggaccgag gccccctacc agtgcatgag acacacacct 360
accctcccca gctttccagg aaccctactg gctgccagac tgatgggcgg gctggtatgt 420
gtggacatgt gttcactgtc attatgctgt ggctccaggt gagggtgagg actgggccta 480
tatagaatcc agataccatt gtcaacttcc cttattcccg tctaagatgt gagcagagtg 540
ccatagtagg ggttctggga agaggtattt ctgatttgtg ggcctctgct tgcttgactt 600
caggtcactt atacttctta ttttgcttgc ctgccttcat ccctcatttc ctccctctca 660
ttcttctttc ctccctccct ttcctggtag cctcctttcc tccccttctg ccttcccctt 720
ccttctttcc ttattctttt ttattttgtt taaatagtac cacagagaaa acaactgaaa 780
aaccacattt ttctacatac agctggggag gtagctgaga acttggcact gcgcacacat 840
actaggttga aagagagttg aggaaaccag aaggccaagt ggatctgctg gcaaaccctg 900
aacctgtctc ctgcgcttgc tctacagttc tgaagttgaa aatcgttttc atgcctagca 960
tctgcttgag ttataaaccc caaggcagcc atgtcataga ctagtgttta ctcttgtttt 1020
gactttgttt taatgcttcc taagacccaa gtgcctcctg ctgtttcctc ctttgtggta 1080
gcctctggcc atctggacct caatccccag ctttcccact ttcagcagtc ctttgctctc 1140
tttgcttcta cctcaaatag ccccaggagt gggctttagt ctccaatatg gagcatctca 1200
agcttctcct gggggatggg gattgggatg ggcggaatct gttttggatc tccgggttat 1260
ttccagtggg tgtaaaagca gagctgggcc tttccctctc ttatccctga gggtgggtaa 1320
gaaggactgt atctacacct gttcttccct accttctctt ttgttaggga ggcctcattc 1380
taagttcctc aagagagtcc ttggcttaaa gctgtagcaa gggtgtgcta ggtgggggat 1440
ttggagcaaa accgtcgagt aggcatgata ctggtatgga gtgggcctgc aaaatcagac 1500
agaaatggct tgagaagccg cagggggagc atgcctgtct ctcagtgata gagtatggga 1560
gggacctccc tagcttggaa aatgagaatt gaaggggtta tgaacaaata ggatgcctag 1620
ttgaggatgt tcccaaagtt ttgtccaatc ttatcattag tagattttat aagccacaga 1680
gacaaaccag aaacggaata atgttacttt ggatgcttta tttttttgtt ctaggtgtgg 1740
ctttgtacat gcagaagaat gctatatgct gcacattttg cctttaaagt cttacgactt 1800
tccccatttt agtctaatgg gaagatacag atgtgcaagt ctgctttttt gttttttgtt 1860
attatttttt tttttgctct gtgttatgga cattttcaga catgcacaga agtggagagg 1920
atggtccttg gaccccatgt gtccatcacc tagctgcatc acttatcagc tatggtcaac 1980
ctggtttcat ctgtatctct ctcttttcac ctgtattgtt tattgaaaat ccaagacact 2040
atgccaatgc aaccgtgact actttgggag attggtagtc tcttttgatg gtgatagtga 2100
tggggtgcac tatcataatc acatcaggtc tgctttttgc ttttaatgtt aactaatgaa 2160
gttccagaga tgggccttag aaatgtgttt taagaattaa caaggagtct caaaaagaaa 2220
tgagagggat gcttcctttc ccttgcatct acaaaacaag agagagactg ttctgttgta 2280
aaactctttc aaaaattctg atatggtaag gtacttgaga cccttcacca gaatgtcaat 2340
ctttttttct gtgtaacatg gaaacttgtg tgaccattag cattgttatc agcttgtact 2400
ggtctcataa ctctggtttt ggaagaataa tttggaaatt gttgctgtgt tctgtgaaaa 2460
taacctcccc aaaataatta gtaactggtt gttctacttg gtaatttgac accctgttaa 2520
taacgcaatt atttctgtgt tcttaaacag tataaatagt tgtaagtttg catgcatgat 2580
ggaaaaataa aaacctgtat ctctgtcaaa aaaaaaaaaa aaaaaa 2626
<210>75
<211>3337
<212>DNA
<213>人
<400>75
gtcgagcctc tagcccgccc gggtttcctt cgcagtcgcg caccgacgct caaacgcgcg 60
ctccaacccg cagcctcctc ctgcctcacc gcccgaagat ggcggctctc aaactcctct 120
cctccgggct tcggctctgc gcctctgccc gcggatctgg ggcaacctgg tacaagggat 180
gtgtttgttc cttttccacc agtgctcatc gccataccaa gttttataca gatccagtag 240
aagctgtaaa agacatccct gatggtgcca cggttttggt tggtggtttt gggctatgtg 300
gaattccaga gaatcttata gatgctttac tgaaaactgg agtaaaagga ctaactgcag 360
tcagcaacaa tgcaggggtt gacaattttg gtttggggct tttgcttcgg tcgaagcaga 420
taaaacgcat ggtctcttca tatgtgggag aaaatgcaga atttgaacga cagtacttat 480
ctggtgaatt agaagtggag ctgacaccac agggcacact tgcagagagg atccgtgcag 540
gcggggctgg agttcctgca ttttacaccc caacagggta tgggaccctg gtacaagaag 600
gaggatcgcc catcaaatac aacaaagatg gcagtgttgc cattgccagt aagccaagag 660
aggtgaggga gttcaatggt cagcacttta ttttggagga agcaattaca ggggattttg 720
ctttggtgaa agcctggaag gcggaccgag caggaaacgt gattttcagg aaaagtgcaa 780
ggaatttcaa cttgccaatg tgcaaagctg cagaaaccac agtggtagag gttgaagaaa 840
ttgtggatat tggagcattt gctccagaag acatccatat tcctcagatt tatgtacatc 900
gccttataaa gggagaaaaa tatgagaaaa gaattgagcg tttatcaatc cggaaagagg 960
gagatgggga agccaaatct gctaaacctg gagatgacgt aagggaacga atcatcaaga 1020
gggccgctct tgagtttgag gatggcatgt atgctaattt gggcatagga atccctctcc 1080
tggccagcaa ttttatcagc ccaaatataa ctgttcatct tcaaagtgaa aatggagttc 1140
tgggtttggg tccatatcca cgacaacatg aagctgatgc agatctcatc aatgcaggca 1200
aggaaacagt tactattctt ccaggagcct ctttcttctc cagcgatgaa tcatttgcaa 1260
tgattagagg tggacacgtc gatctgacaa tgctaggagc gatgcaggtt tccaaatatg 1320
gtgacctggc taactggatg atacctggga agatggtgaa aggaatggga ggtgctatgg 1380
atttagtgtc cagtgcgaaa accaaagtgg tggtcaccat ggagcattct gcaaagggaa 1440
atgcacataa aatcatggag aaatgtacat taccattgac tggaaagcaa tgtgtcaacc 1500
gcattattac tgaaaaggct gtgtttgatg tggacaagaa gaaagggttg actctgattg 1560
agctctggga aggcctgaca gtggatgacg tacaaaagag tactgggtgt gattttgcag 1620
tttcaccaaa actcatgcca atgcagcaga tcgcaaattg aaatatggat atttgtacca 1680
ggctgcgtgt ttttcatttt aaacacacaa gatttaattg aaaggacatc aataatcata 1740
attgtgtatt taacaggtgg ttttttatta gttttcttgt gtttcagact ttatgcagcc 1800
atataaactg ttctctaggc atgctgtgac attttaataa aaagcaaaag gagcatttat 1860
aattatctca tttgttaagg ctgagaaggt tgtttttata ataggtaatt atattgaatg 1920
cattttcact gaatatggta tgtatgctaa attatatgaa cctttcccca agaagggccc 1980
tagaaattga tgtggctttc ctcttaaata ttaattatta gtcctgaaag aaagataaca 2040
tatgtgattt ttgtggttag gagagttgct gtcatgattg ttttttcttc agcctcctct 2100
gacttttctt ttggggcttc agattttatg attacatctt gtccccctag aacatccccc 2160
ttcctcccat actgctttta aacagatgcc caagaaggca agcaggaatg cctcttgtgg 2220
gggagggcag ggagaaataa ctagttcaaa ccaactatct atctatgctt tgcaaagact 2280
aaggcgtatt ataggaagag ggctagaaac ctaactgatt cttctcagtt ttctcatttt 2340
aaaacagccc agtattcctt tgtatcctca agggtccttg agaatacttc tgttattgaa 2400
accctgtggg ctacttgtac tgtacctcct ctcaagccaa gaagggctgt gggataattt 2460
accatgaatc cttagtagca atgacagcag agttaaaaaa taaaaggtgt tttactttca 2520
ggctcttgtt ttggttcaga ggagatttta aatattgaat gacacttcta cagaacaacg 2580
gtttttcttc tgccaaggct acttccttta acgaagtgcc tttaattcag ccttatccaa 2640
ctagggaaaa taatgttgga caagtctagg atttgaagag tcagtgaact tttagtgtca 2700
gggaataaac atggtgggta gattaggttt gaaaaaaact tccttagagg tatttattct 2760
caatacctga caggggccca tgggaatgac ttcagaagca tcccggataa tagatgggta 2820
aaaagtctag gcaccctgaa gaacaggtga gacagctggc ctctggacag aggtaggcat 2880
agtacagtac gatatatcat tcctctggtc ctaaatatac aaacttattc atgtttttag 2940
gtgatgatgg tcattgaaac tcacttcttt tcaggtgtag ctacaattgt gtaatgtaca 3000
atattagaga aaggacaggc tttttatgag taacacacac catatataaa acagcctttc 3060
tggctgacca catggttaaa tgcatacctt cccagtactg gggggaaaat gacccttctt 3120
agaatgtgca agttccatag agtaatatat tgatatgatt ttgaaaagaa ttgttgatag 3180
ttacatcttc aaacttatca ttccagtatg catctttaag ataatgtgat tctaagtaga 3240
tgactttata ttcttgatta aagagtgcta tacatgttaa gaaatgcatt aaggaataca 3300
ataaatattc taaactgatg aaaaaaaaaa aaaaaaa 3337
<210>76
<211>2460
<212>DNA
<213>人
<400>76
aaagtcaaac cccgacaccg cggcgggccg gtgagctcac tagctgaccc ggcaggtcag 60
gatctggctt agcggcgccg cgagctccag tgcgcgcacc cgtggccgcc tcccagccct 120
ctttgccgga cgagctctgg gccgccacaa gactaaggaa tggccacccc gcccaagaga 180
agctgcccgt ctttctcagc cagctctgag gggacccgca tcaagaaaat ctccatcgaa 240
gggaacatcg ctgcagggaa gtcaacattt gtgaatatcc ttaaacaatt gtgtgaagat 300
tgggaagtgg ttcctgaacc tgttgccaga tggtgcaatg ttcaaagtac tcaagatgaa 360
tttgaggaac ttacaatgtc tcagaaaaat ggtgggaatg ttcttcagat gatgtatgag 420
aaacctgaac gatggtcttt taccttccaa acatatgcct gtctcagtcg aataagagct 480
cagcttgcct ctctgaatgg caagctcaaa gatgcagaga aacctgtatt attttttgaa 540
cgatctgtgt atagtgacag gtatattttt gcatctaatt tgtatgaatc tgaatgcatg 600
aatgagacag agtggacaat ttatcaagac tggcatgact ggatgaataa ccaatttggc 660
caaagccttg aattggatgg aatcatttat cttcaagcca ctccagagac atgcttacat 720
agaatatatt tacggggaag aaatgaagag caaggcattc ctcttgaata tttagagaag 780
cttcattata aacatgaaag ctggctcctg cataggacac tgaaaaccaa cttcgattat 840
cttcaagagg tgcctatctt aacactggat gttaatgaag actttaaaga caaatatgaa 900
agtctggttg aaaaggtcaa agagtttttg agtactttgt gatcttgctg aagactacag 960
gcagccaaat ggttccagat acttcagctt tgtgtatctt cgtaacttca tattaatata 1020
agtttcttta gaaaacccaa gtttttaatc gtttttgttt taaggaaaaa agatttttaa 1080
aatgaatctt atgcaaaact ttttgatcag tttcttttct tttgtttttt ttttaaaaaa 1140
gacatttaaa gacaaagaca ttatttctca tagcaggaaa tgtagaggta gatggttcca 1200
gtatcagcat agtgactaaa ctacattata aaagatccag cttccttctg tcattcccct 1260
cttttgtctt cctcagcagg ttggcttttt tccctggtgc ctctcacttc gttggtgacc 1320
agtttcttaa actgaaagct ttaatgttac atagtaaatg gtagtgtgtc ctgtgtaaat 1380
tagtgtacct attaaaagtt gcaaagtgga attaaaggaa tccctagaat aaggattctg 1440
aagttttatt ttaaattatt atcttcttaa cagtttagtc ccacctctta cttcctgcct 1500
cagtctgctt tctctactgt ctggattaat taggcagcct gctataaagt taaagtcaca 1560
catttctatt ttgcaaacac tgtgattact ctttgctttg tagtttgctt tgctttgtag 1620
ggttctgctt ttaagttttt ctctttttca gacaaattac tgataaaaat gatattgctc 1680
tatatgtaat atatcctgaa agcattattt tttgttgaat aggaaataaa attaatgaag 1740
acagaggcta gaaagcatcc attaattaat gagacacact taactactta tctctaaacc 1800
atctatgtga atatttgtaa aaataatgaa tggactcatc ttagttctgt atataaatat 1860
attttctttc tagtttgttt agttaaggtg tgcagtgttt ttcctgtgta ttaaaccttt 1920
ccattttacg ttttagaaaa ttttatgtat tttaaaataa ggggaagagt cattttcacc 1980
tttaaactac tatttttctt tccaagtcat ttttgttttt ggtttcttat tcaaagatga 2040
taatttagtg gattaaccag tccagacgca ctgatctttg caaaggagac ttaatttcaa 2100
atctgtaatt accatacata aactgtctca ttatacgtat gcattttttt agtttgtttt 2160
tgtttggtat aaattaattt gttaattaaa tatttcttaa gtataaacct tatgaactac 2220
agtggagcta cactcattga aatgtaattt cagttctaaa aagatgtaat aatcatttta 2280
gaattaaaat ttattctact tttaaataaa ttatgaatat taaaggtgaa aattgtataa 2340
attactttga ttccatttta agtggagaca tatttcagtg atttttagta acctttaaaa 2400
atgtataatg acttttaaaa tttgtagaat tgaaaagacg ctaataaaaa tttattattt 2460
<210>77
<211>7680
<212>DNA
<213>人
<400>77
gcggacactc ctctcggctc ctccccggca gcggcggcgg ctcggagcgg gctccggggc 60
tcgggtgcag cggccagcgg gcctggcggc gaggattacc cggggaagtg gttgtctcct 120
ggctggagcc gcgagacggg cgctcagggc gcggggccgg cggcggcgaa cgagaggacg 180
gactctggcg gccgggtcgt tggccggggg agcgcgggca ccgggcgagc aggccgcgtc 240
gcgctcacca tggtcagcta ctgggacacc ggggtcctgc tgtgcgcgct gctcagctgt 300
ctgcttctca caggatctag ttcaggttca aaattaaaag atcctgaact gagtttaaaa 360
ggcacccagc acatcatgca agcaggccag acactgcatc tccaatgcag gggggaagca 420
gcccataaat ggtctttgcc tgaaatggtg agtaaggaaa gcgaaaggct gagcataact 480
aaatctgcct gtggaagaaa tggcaaacaa ttctgcagta ctttaacctt gaacacagct 540
caagcaaacc acactggctt ctacagctgc aaatatctag ctgtacctac ttcaaagaag 600
aaggaaacag aatctgcaat ctatatattt attagtgata caggtagacc tttcgtagag 660
atgtacagtg aaatccccga aattatacac atgactgaag gaagggagct cgtcattccc 720
tgccgggtta cgtcacctaa catcactgtt actttaaaaa agtttccact tgacactttg 780
atccctgatg gaaaacgcat aatctgggac agtagaaagg gcttcatcat atcaaatgca 840
acgtacaaag aaatagggct tctgacctgt gaagcaacag tcaatgggca tttgtataag 900
acaaactatc tcacacatcg acaaaccaat acaatcatag atgtccaaat aagcacacca 960
cgcccagtca aattacttag aggccatact cttgtcctca attgtactgc taccactccc 1020
ttgaacacga gagttcaaat gacctggagt taccctgatg aaaaaaataa gagagcttcc 1080
gtaaggcgac gaattgacca aagcaattcc catgccaaca tattctacag tgttcttact 1140
attgacaaaa tgcagaacaa agacaaagga ctttatactt gtcgtgtaag gagtggacca 1200
tcattcaaat ctgttaacac ctcagtgcat atatatgata aagcattcat cactgtgaaa 1260
catcgaaaac agcaggtgct tgaaaccgta gctggcaagc ggtcttaccg gctctctatg 1320
aaagtgaagg catttccctc gccggaagtt gtatggttaa aagatgggtt acctgcgact 1380
gagaaatctg ctcgctattt gactcgtggc tactcgttaa ttatcaagga cgtaactgaa 1440
gaggatgcag ggaattatac aatcttgctg agcataaaac agtcaaatgt gtttaaaaac 1500
ctcactgcca ctctaattgt caatgtgaaa ccccagattt acgaaaaggc cgtgtcatcg 1560
tttccagacc cggctctcta cccactgggc agcagacaaa tcctgacttg taccgcatat 1620
ggtatccctc aacctacaat caagtggttc tggcacccct gtaaccataa tcattccgaa 1680
gcaaggtgtg acttttgttc caataatgaa gagtccttta tcctggatgc tgacagcaac 1740
atgggaaaca gaattgagag catcactcag cgcatggcaa taatagaagg aaagaataag 1800
atggctagca ccttggttgt ggctgactct agaatttctg gaatctacat ttgcatagct 1860
tccaataaag ttgggactgt gggaagaaac ataagctttt atatcacaga tgtgccaaat 1920
gggtttcatg ttaacttgga aaaaatgccg acggaaggag aggacctgaa actgtcttgc 1980
acagttaaca agttcttata cagagacgtt acttggattt tactgcggac agttaataac 2040
agaacaatgc actacagtat tagcaagcaa aaaatggcca tcactaagga gcactccatc 2100
actcttaatc ttaccatcat gaatgtttcc ctgcaagatt caggcaccta tgcctgcaga 2160
gccaggaatg tatacacagg ggaagaaatc ctccagaaga aagaaattac aatcagagat 2220
caggaagcac catacctcct gcgaaacctc agtgatcaca cagtggccat cagcagttcc 2280
accactttag actgtcatgc taatggtgtc cccgagcctc agatcacttg gtttaaaaac 2340
aaccacaaaa tacaacaaga gcctggaatt attttaggac caggaagcag cacgctgttt 2400
attgaaagag tcacagaaga ggatgaaggt gtctatcact gcaaagccac caaccagaag 2460
ggctctgtgg aaagttcagc atacctcact gttcaaggaa cctcggacaa gtctaatctg 2520
gagctgatca ctctaacatg cacctgtgtg gctgcgactc tcttctggct cctattaacc 2580
ctccttatcc gaaaaatgaa aaggtcttct tctgaaataa agactgacta cctatcaatt 2640
ataatggacc cagatgaagt tcctttggat gagcagtgtg agcggctccc ttatgatgcc 2700
agcaagtggg agtttgcccg ggagagactt aaactgggca aatcacttgg aagaggggct 2760
tttggaaaag tggttcaagc atcagcattt ggcattaaga aatcacctac gtgccggact 2820
gtggctgtga aaatgctgaa agagggggcc acggccagcg agtacaaagc tctgatgact 2880
gagctaaaaa tcttgaccca cattggccac catctgaacg tggttaacct gctgggagcc 2940
tgcaccaagc aaggagggcc tctgatggtg attgttgaat actgcaaata tggaaatctc 3000
tccaactacc tcaagagcaa acgtgactta ttttttctca acaaggatgc agcactacac 3060
atggagccta agaaagaaaa aatggagcca ggcctggaac aaggcaagaa accaagacta 3120
gatagcgtca ccagcagcga aagctttgcg agctccggct ttcaggaaga taaaagtctg 3180
agtgatgttg aggaagagga ggattctgac ggtttctaca aggagcccat cactatggaa 3240
gatctgattt cttacagttt tcaagtggcc agaggcatgg agttcctgtc ttccagaaag 3300
tgcattcatc gggacctggc agcgagaaac attcttttat ctgagaacaa cgtggtgaag 3360
atttgtgatt ttggccttgc ccgggatatt tataagaacc ccgattatgt gagaaaagga 3420
gatactcgac ttcctctgaa atggatggct cccgaatcta tctttgacaa aatctacagc 3480
accaagagcg acgtgtggtc ttacggagta ttgctgtggg aaatcttctc cttaggtggg 3540
tctccatacc caggagtaca aatggatgag gacttttgca gtcgcctgag ggaaggcatg 3600
aggatgagag ctcctgagta ctctactcct gaaatctatc agatcatgct ggactgctgg 3660
cacagagacc caaaagaaag gccaagattt gcagaacttg tggaaaaact aggtgatttg 3720
cttcaagcaa atgtacaaca ggatggtaaa gactacatcc caatcaatgc catactgaca 3780
ggaaatagtg ggtttacata ctcaactcct gccttctctg aggacttctt caaggaaagt 3840
atttcagctc cgaagtttaa ttcaggaagc tctgatgatg tcagatatgt aaatgctttc 3900
aagttcatga gcctggaaag aatcaaaacc tttgaagaac ttttaccgaa tgccacctcc 3960
atgtttgatg actaccaggg cgacagcagc actctgttgg cctctcccat gctgaagcgc 4020
ttcacctgga ctgacagcaa acccaaggcc tcgctcaaga ttgacttgag agtaaccagt 4080
aaaagtaagg agtcggggct gtctgatgtc agcaggccca gtttctgcca ttccagctgt 4140
gggcacgtca gcgaaggcaa gcgcaggttc acctacgacc acgctgagct ggaaaggaaa 4200
atcgcgtgct gctccccgcc cccagactac aactcggtgg tcctgtactc caccccaccc 4260
atctagagtt tgacacgaag ccttatttct agaagcacat gtgtatttat acccccagga 4320
aactagcttt tgccagtatt atgcatatat aagtttacac ctttatcttt ccatgggagc 4380
cagctgcttt ttgtgatttt tttaatagtg cttttttttt ttgactaaca agaatgtaac 4440
tccagataga gaaatagtga caagtgaaga acactactgc taaatcctca tgttactcag 4500
tgttagagaa atccttccta aacccaatga cttccctgct ccaacccccg ccacctcagg 4560
gcacgcagga ccagtttgat tgaggagctg cactgatcac ccaatgcatc acgtacccca 4620
ctgggccagc cctgcagccc aaaacccagg gcaacaagcc cgttagcccc aggggatcac 4680
tggctggcct gagcaacatc tcgggagtcc tctagcaggc ctaagacatg tgaggaggaa 4740
aaggaaaaaa agcaaaaagc aagggagaaa agagaaaccg ggagaaggca tgagaaagaa 4800
tttgagacgc accatgtggg cacggagggg gacggggctc agcaatgcca tttcagtggc 4860
ttcccagctc tgacccttct acatttgagg gcccagccag gagcagatgg acagcgatga 4920
ggggacattt tctggattct gggaggcaag aaaaggacaa atatcttttt tggaactaaa 4980
gcaaatttta gacctttacc tatggaagtg gttctatgtc cattctcatt cgtggcatgt 5040
tttgatttgt agcactgagg gtggcactca actctgagcc catacttttg gctcctctag 5100
taagatgcac tgaaaactta gccagagtta ggttgtctcc aggccatgat ggccttacac 5160
tgaaaatgtc acattctatt ttgggtatta atatatagtc cagacactta actcaatttc 5220
ttggtattat tctgttttgc acagttagtt gtgaaagaaa gctgagaaga atgaaaatgc 5280
agtcctgagg agagttttct ccatatcaaa acgagggctg atggaggaaa aaggtcaata 5340
aggtcaaggg aagaccccgt ctctatacca accaaaccaa ttcaccaaca cagttgggac 5400
ccaaaacaca ggaagtcagt cacgtttcct tttcatttaa tggggattcc actatctcac 5460
actaatctga aaggatgtgg aagagcatta gctggcgcat attaagcact ttaagctcct 5520
tgagtaaaaa ggtggtatgt aatttatgca aggtatttct ccagttggga ctcaggatat 5580
tagttaatga gccatcacta gaagaaaagc ccattttcaa ctgctttgaa acttgcctgg 5640
ggtctgagca tgatgggaat agggagacag ggtaggaaag ggcgcctact cttcagggtc 5700
taaagatcaa gtgggccttg gatcgctaag ctggctctgt ttgatgctat ttatgcaagt 5760
tagggtctat gtatttagga tgcgcctact cttcagggtc taaagatcaa gtgggccttg 5820
gatcgctaag ctggctctgt ttgatgctat ttatgcaagt tagggtctat gtatttagga 5880
tgtctgcacc ttctgcagcc agtcagaagc tggagaggca acagtggatt gctgcttctt 5940
ggggagaaga gtatgcttcc ttttatccat gtaatttaac tgtagaacct gagctctaag 6000
taaccgaaga atgtatgcct ctgttcttat gtgccacatc cttgtttaaa ggctctctgt 6060
atgaagagat gggaccgtca tcagcacatt ccctagtgag cctactggct cctggcagcg 6120
gcttttgtgg aagactcact agccagaaga gaggagtggg acagtcctct ccaccaagat 6180
ctaaatccaa acaaaagcag gctagagcca gaagagagga caaatctttg ttgttcctct 6240
tctttacaca tacgcaaacc acctgtgaca gctggcaatt ttataaatca ggtaactgga 6300
aggaggttaa actcagaaaa aagaagacct cagtcaattc tctacttttt tttttttttt 6360
tccaaatcag ataatagccc agcaaatagt gataacaaat aaaaccttag ctgttcatgt 6420
cttgatttca ataattaatt cttaatcatt aagagaccat aataaatact ccttttcaag 6480
agaaaagcaa aaccattaga attgttactc agctccttca aactcaggtt tgtagcatac 6540
atgagtccat ccatcagtca aagaatggtt ccatctggag tcttaatgta gaaagaaaaa 6600
tggagacttg taataatgag ctagttacaa agtgcttgtt cattaaaata gcactgaaaa 6660
ttgaaacatg aattaactga taatattcca atcatttgcc atttatgaca aaaatggttg 6720
gcactaacaa agaacgagca cttcctttca gagtttctga gataatgtac gtggaacagt 6780
ctgggtggaa tggggctgaa accatgtgca agtctgtgtc ttgtcagtcc aagaagtgac 6840
accgagatgt taattttagg gacccgtgcc ttgtttccta gcccacaaga atgcaaacat 6900
caaacagata ctcgctagcc tcatttaaat tgattaaagg aggagtgcat ctttggccga 6960
cagtggtgta actgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgggtgtg 7020
ggtgtatgtg tgttttgtgc ataactattt aaggaaactg gaattttaaa gttactttta 7080
tacaaaccaa gaatatatgc tacagatata agacagacat ggtttggtcc tatatttcta 7140
gtcatgatga atgtattttg tataccatct tcatataata tacttaaaaa tatttcttaa 7200
ttgggatttg taatcgtacc aacttaattg ataaacttgg caactgcttt tatgttctgt 7260
ctccttccat aaatttttca aaatactaat tcaacaaaga aaaagctctt ttttttccta 7320
aaataaactc aaatttatcc ttgtttagag cagagaaaaa ttaagaaaaa ctttgaaatg 7380
gtctcaaaaa attgctaaat attttcaatg gaaaactaaa tgttagttta gctgattgta 7440
tggggttttc gaacctttca ctttttgttt gttttaccta tttcacaact gtgtaaattg 7500
ccaataattc ctgtccatga aaatgcaaat tatccagtgt agatatattt gaccatcacc 7560
ctatggatat tggctagttt tgcctttatt aagcaaattc atttcagcct gaatgtctgc 7620
ctatatattc tctgctcttt gtattctcct ttgaacccgt taaaacatcc tgtggcactc 7680
<210>78
<211>3160
<212>DNA
<213>人
<400>78
attctcgccg cgcccgggcg gacgatccag cgaacagccc cgcttctaac ccgagatgct 60
gctgccggcg cccgcgctcc gccgcgccct gctgtcccgc ccctggaccg gggccggcct 120
gcggtggaag cacacctcct ccctgaaggt ggccaacgag cccgtcttag ccttcacgca 180
gggcagccct gagcgagatg ccctgcaaaa ggccttgaag gacctgaagg gccggatgga 240
agccatccca tgcgtggtgg gggatgagga ggtgtggacg tcggacgtgc agtaccaagt 300
gtcgcctttt aaccatggac ataaggtggc caagttctgt tatgcagaca agagcctgct 360
caacaaagcc attgaggctg ccctggctgc ccggaaagag tgggacctga agcctattgc 420
agaccgggcc cagatcttcc tgaaggcggc agacatgctg agtgggccgc gcagggctga 480
gatcctcgcc aagaccatgg tgggacaggg taagaccgtg atccaagcgg agattgacgc 540
tgcagcggaa ctcatcgact tcttccggtt caatgccaag tatgcggtgg agctggaggg 600
gcagcagccc atcagcgtgc ccccgagcac caacagcacg gtgtaccggg gtctggaggg 660
cttcgtggcg gccatctcgc cctttaactt cactgcaatc ggcggcaacc tggcgggggc 720
accggccctg atgggcaacg tggtcctatg gaagcccagt gacactgcca tgctggccag 780
ctatgctgtc taccgcatcc ttcgggaggc tggcctgccc cccaacatca tccagtttgt 840
gccagctgat gggcccctat ttggggacac tgtcaccagc tcagagcacc tctgtggcat 900
caacttcaca ggcagtgtgc ccaccttcaa acacctgtgg aagcaggtgg cccagaacct 960
ggaccggttc cacaccttcc cacgcctggc tggagagtgc ggcggaaaga acttccactt 1020
cgtgcaccgc tcggccgacg tggagagcgt ggtgagcggg accctccgct cagccttcga 1080
gtacggtggc cagaagtgtt ccgcctgctc gcgtctctac gtgccgcact cgctgtggcc 1140
gcagatcaaa gggcggctgc tggaggagca cagtcggatc aaagtgggcg accctgcaga 1200
ggattttggg accttcttct ctgcagtgat tgatgccaag tcctttgccc gtatcaagaa 1260
gtggctggag cacgcgcgct cctcgcccag cctcaccatc ctggctgggg gcaagtgtga 1320
tgactccgtg ggctactttg tggagccctg catcgtggag agcaaggacc ctcaggagcc 1380
catcatgaag gaggagatct tcgggcctgt actgtctgtg tacgtctacc cggacgacaa 1440
gtacaaggag acgctgcagc tggttgacag caccaccagc tatggcctca cgggggcagt 1500
gttctcccag gataaggacg tcgtgcagga ggccacaaag gtgctgagga atgctgccgg 1560
caacttctac atcaacgaca agtccactgg ctcgatagtg ggccagcagc cctttggggg 1620
ggcccgagcc tctggaacca atgacaagcc agggggccca cactacatcc tgcgctggac 1680
gtcgccgcag gtcatcaagg agacacataa gcccctgggg gactggagct acgcgtacat 1740
gcagtgagcc cctctcgggc tccaccgtcc agctgtctgt ccgtccaggt ggccgacctc 1800
actgcacaga ccccactcca gcccctccac cccttcctca tgcacagctg cctttctata 1860
atccgggctt gactcccttc ttaccactgt attctggcct ctcccatgcc tcaggctctg 1920
gtttgagatc gtgctgggga ggaacatggc cactacccct tatcccatcg gccatgtggg 1980
aggtatgacc ctggtgcctg gcaggttctc cctctgccct ccactgggcc cagtggctca 2040
gggacctggg gaaaggagat ggagcagctc ttgggatcct ttggggaaaa ggaggccatt 2100
ctgggcccct tggcaaacct caccactcac agaggctcct ggccttgatc cctgcccctc 2160
caggtgtcca gggtaaagtg taactcagac tgacctgtgg ggcacagggg gcaccagctg 2220
gccttgccct ctctggtctg ggctgtctac cttcctcact gtatctttgc ccagacccac 2280
ctgggccagt aggcccctgt ccccagccac acaccttaga tgctggcatg ccttactcca 2340
ggtgcctgtg tttggccgag gcctgtgtga ttcccggtct gcaccacatg gcggggttgg 2400
ggggccgctg gaggccacct gccaaggcgt gggatgggat ggtcctgccg gtttaggccg 2460
tgattctgga aaaccttgga tgggccttcg tcctatgtca gccttccctt tgatcctcag 2520
gccctacctg tagagacctc cactcctaga gccagtctca gggtctggga tttccctgca 2580
ggagctcagc caccactgtg ccatggtgac acaggccaag gcagacattg gccctccctt 2640
ctcccagccc ccagaggcct ggccttgggt tcgtcagcat gggccgagga cgttgcctgt 2700
agaatcctcc tctgcctggg agtggctctg tgtggaccag tccctcactg gcccattctt 2760
tttttgacgc agccaatctg tgaccacgat tcctcccaca gatgcctcct gcttggattc 2820
tgagtggtca gagatctgta aagcatgact ttcaaggatg gttcttaggg gactgtgaaa 2880
gtgttgggtc ttcctccagg atgcctgcat gggaccccac ccggagctgg tgtggccatt 2940
ccccaagtgc cactggccca tggatggggg tgggtgctgg tgccagctgg gctgggtgtg 3000
ggttctgtgt ccttccagga tatgtgtcat ttcccatgag gggccggggc aggtggctgg 3060
gtgggggcac aggctggagt attcttagtt ctactggttc tacactgtga ggtggcaatg 3120
ggatttgctc agatgccacc caataaaatg cctgttactt 3160
<210>79
<211>1546
<212>DNA
<213>人
<400>79
cacggccgga gagacgcgga ggaggagaca tgagccggcg ggcgcccaga cggagcggcc 60
gtgacgcttt cgcgctgcag ccgcgcgccc cgaccccgga gcgctgaccc ctggccccac 120
gcagctccgc gcccgggccg gagagcgcaa ctcggcttcc agacccgccg cgcatgctgt 180
ccccggactg agccgggcag ccagcctccc acggacgccc ggacggccgg ccggccagca 240
gtgagcgagc ttccccgcac cggccaggcg cctcctgcac agcggctgcc gccccgcagc 300
ccctgcgcca gcccggaggg cgcagcgctc gggaggagcc gcgcggggcg ctgatgccgc 360
agggcgcgcc gcggagcgcc ccggagcagc agagtctgca gcagcagcag ccggcgagga 420
gggagcagca gcagcggcgg cggcggcggc ggcggcggcg gaggcgcccg gtcccggccg 480
cgcggagcgg acatgtgcag gctgggctag gagccgccgc ctccctcccg cccagcgatg 540
tattcagcgc cctccgcctg cacttgcctg tgtttacact tcctgctgct gtgcttccag 600
gtacaggtgc tggttgccga ggagaacgtg gacttccgca tccacgtgga gaaccagacg 660
cgggctcggg acgatgtgag ccgtaagcag ctgcggctgt accagctcta cagccggacc 720
agtgggaaac acatccaggt cctgggccgc aggatcagtg cccgcggcga ggatggggac 780
aagtatgccc agctcctagt ggagacagac accttcggta gtcaagtccg gatcaagggc 840
aaggagacgg aattctacct gtgcatgaac cgcaaaggca agctcgtggg gaagcccgat 900
ggcaccagca aggagtgtgt gttcatcgag aaggttctgg agaacaacta cacggccctg 960
atgtcggcta agtactccgg ctggtacgtg ggcttcacca agaaggggcg gccgcggaag 1020
ggccccaaga cccgggagaa ccagcaggac gtgcatttca tgaagcgcta ccccaagggg 1080
cagccggagc ttcagaagcc cttcaagtac acgacggtga ccaagaggtc ccgtcggatc 1140
cggcccacac accctgccta ggccaccccg ccgcggcccc tcaggtcgcc ctggccacac 1200
tcacactccc agaaaactgc atcagaggaa tatttttaca tgaaaaataa ggaagaagct 1260
ctatttttgt acattgtgtt taaaagaaga caaaaactga accaaaactc ttggggggag 1320
gggtgataag gattttattg ttgacttgaa acccccgatg acaaaagact cacgcaaagg 1380
gactgtagtc aacccacagg tgcttgtctc tctctaggaa cagacaactc taaactcgtc 1440
cccagaggag gacttgaatg aggaaaccaa cactttgaga aaccaaagtc ctttttccca 1500
aaggttctga aaggaaaaaa aaaaaaaaac aaaaaaaaaa aaaaaa 1546
<210>80
<211>2819
<212>DNA
<213>人
<400>80
ctgggcccag ctcccccgag aggtggtcgg atcctctggg ctgctcggtc gatgcctgtg 60
ccactgacgt ccaggcatga ggtggttcct gccctggacg ctggcagcag tgacagcagc 120
agccgccagc accgtcctgg ccacggccct ctctccagcc cctacgacca tggactttac 180
cccagctcca ctggaggaca cctcctcacg cccccaattc tgcaagtggc catgtgagtg 240
cccgccatcc ccaccccgct gcccgctggg ggtcagcctc atcacagatg gctgtgagtg 300
ctgtaagatg tgcgctcagc agcttgggga caactgcacg gaggctgcca tctgtgaccc 360
ccaccggggc ctctactgtg actacagcgg ggaccgcccg aggtacgcaa taggagtgtg 420
tgcacaggtg gtcggtgtgg gctgcgtcct ggatggggtg cgctacaaca acggccagtc 480
cttccagcct aactgcaagt acaactgcac gtgcatcgac ggcgcggtgg gctgcacacc 540
actgtgcctc cgagtgcgcc ccccgcgtct ctggtgcccc cacccgcggc gcgtgagcat 600
acctggccac tgctgtgagc agtgggtatg tgaggacgac gccaagaggc cacgcaagac 660
cgcaccccgt gacacaggag ccttcgatgc tgtgggtgag gtggaggcat ggcacaggaa 720
ctgcatagcc tacacaagcc cctggagccc ttgctccacc agctgcggcc tgggggtctc 780
cactcggatc tccaatgtta acgcccagtg ctggcctgag caagagagcc gcctctgcaa 840
cttgcggcca tgcgatgtgg acatccatac actcattaag gcagggaaga agtgtctggc 900
tgtgtaccag ccagaggcat ccatgaactt cacacttgcg ggctgcatca gcacacgctc 960
ctatcaaccc aagtactgtg gagtttgcat ggacaatagg tgctgcatcc cctacaagtc 1020
taagactatc gacgtgtcct tccagtgtcc tgatgggctt ggcttctccc gccaggtcct 1080
atggattaat gcctgcttct gtaacctgag ctgtaggaat cccaatgaca tctttgctga 1140
cttggaatcc taccctgact tctcagaaat tgccaactag gcaggcacaa atcttgggtc 1200
ttggggacta acccaatgcc tgtgaagcag tcagccctta tggccaataa cttttcacca 1260
atgagcctta gttaccctga tctggaccct tggcctccat ttctgtctct aaccattcaa 1320
atgacgcctg atggtgctgc tcaggcccat gctatgagtt ttctccttga tatcattcag 1380
catctactct aaagaaaaat gcctgtctct agctgttctg gactacaccc aagcctgatc 1440
cagcctttcc aagtcactag aagtcctgct ggatcttgcc taaatcccaa gaaatggaat 1500
caggtagact tttaatatca ctaatttctt ctttagatgc caaaccacaa gactctttgg 1560
gtccattcag atgaatagat ggaatttgga acaatagaat aatctattat ttggagcctg 1620
ccaagaggta ctgtaatggg taattctgac gtcagcgcac caaaactatc ctgattccaa 1680
atatgtatgc acctcaaggt catcaaacat ttgccaagtg agttgaatag ttgcttaatt 1740
ttgattttta atggaaagtt gtatccatta acctgggcat tgttgaggtt aagtttctct 1800
tcacccctac actgtgaagg gtacagatta ggtttgtccc agtcagaaat aaaatttgat 1860
aaacattcct gttgatggga aaagccccca gttaatactc cagagacagg gaaaggtcag 1920
cccgtttcag aaggaccaat tgactctcac actgaatcag ctgctgactg gcagggcttt 1980
gggcagttgg ccaggctctt ccttgaatct tctcccttgt cctgcttggg gttcatagga 2040
attggtaagg cctctggact ggcctgtctg gcccctgaga gtggtgccct ggaacactcc 2100
tctactctta cagagccttg agagacccag ctgcagacca tgccagaccc actgaaatga 2160
ccaagacagg ttcaggtagg ggtgtgggtc aaaccaagaa gtgggtgccc ttggtagcag 2220
cctggggtga cctctagagc tggaggctgt gggactccag gggcccccgt gttcaggaca 2280
catctattgc agagactcat ttcacagcct ttcgttctgc tgaccaaatg gccagttttc 2340
tggtaggaag atggaggttt accggttgtt tagaaacaga aatagactta ataaaggttt 2400
aaagctgaag aggttgaagc taaaaggaaa aggttgttgt taatgaatat caggctatta 2460
tttattgtat taggaaaata taatatttac tgttagaatt cttttattta gggccttttc 2520
tgtgccagac attgctctca gtgctttgca tgtattagct cactgaatct tcacgacaat 2580
gttgagaagt tcccattatt atttctgttc ttacaaatgt gaaacggaag ctcatagagg 2640
tgagaaaact caaccagagt cacccagttg gtgactggga aagttaggat tcagatcgaa 2700
attggactgt ctttataacc catattttcc ccctgttttt agagcttcca aatgtgtcag 2760
aataggaaaa cattgcaata aatggcttga ttttttaaaa aaaaaaaaaa aaaaaaaaa 2819
<210>81
<211>2584
<212>DNA
<213>人
<400>81
tggcggcggc ggcggcggtt gtcccggctg tgccggttgg tgtggcccgt cagcccgcgt 60
accacagcgc ccgggccgcg tcgagcccag tacagccaag ccgctgcggc cgggtccggc 120
gcgggcggcg cgcgcagacg gagggcggcg gccgcggcca gggcggcccg tgggaccgcg 180
ggcccccggc gcagcgctgc ccggctcccg gccctgccgg cctcctccct tggcgccgcg 240
gccatggcgg ccagcgcgaa gcggaagcag gaggagaagc acctgaagat gctgcgggac 300
atgaccggcc tcccgcgcaa ccgaaagtgc ttcgactgcg accagcgcgg ccccacctac 360
gttaacatga cggtcggctc cttcgtgtgt acctcctgct ccggcagcct gcgaggatta 420
aatccaccac acagggtgaa atctatctcc atgacaacat tcacacaaca ggaaattgaa 480
ttcttacaaa aacatggaaa tgaagtctgt aaacagattt ggctaggatt atttgatgat 540
agatcttcag caattccaga cttcagggat ccacaaaaag tgaaagagtt tctacaagaa 600
aagtatgaaa agaaaagatg gtatgtcccg ccagaacaag ccaaagtcgt ggcatcagtt 660
catgcatcta tttcagggtc ctctgccagt agcacaagca gcacacctga ggtcaaacca 720
ctgaaatctc ttttagggga ttctgcacca acactgcact taaataaggg cacacctagt 780
cagtccccag ttgtaggtcg ttctcaaggg cagcagcagg agaagaagca atttgacctt 840
ttaagtgatc tcggctcaga catctttgct gctccagctc ctcagtcaac agctacagcc 900
aattttgcta actttgcaca tttcaacagt catgcagctc agaattctgc aaatgcagat 960
tttgcaaact ttgatgcatt tggacagtct agtggttcga gtaattttgg aggtttcccc 1020
acagcaagtc actctccttt tcagccccaa actacaggtg gaagtgctgc atcagtaaat 1080
gctaattttg ctcattttga taacttcccc aaatcctcca gtgctgattt tggaaccttc 1140
aatacttccc agagtcatca aacagcatca gctgttagta aagtttcaac gaacaaagct 1200
ggtttacaga ctgcagacaa atatgcagca cttgctaatt tagacaatat cttcagtgcc 1260
gggcaaggtg gtgatcaggg aagtggcttt gggaccacag gtaaagctcc tgttggttct 1320
gtggtttcag ttcccagtca gtcaagtgca tcttcagaca agtatgcagc tctggcagaa 1380
ctagacagcg ttttcagttc tgcagccacc tccagtaatg cgtatacttc cacaagtaat 1440
gctagcagca atgtttttgg aacagtgcca gtggttgctt ctgcacagac acagcctgct 1500
tcatcaagtg tgcctgctcc atttggacgt acgccttcca caaatccatt tgttgctgct 1560
gctggtcctt ctgtggcatc ttctacaaac ccatttcaga ccaatgccag aggagcaaca 1620
gcggcaacct ttggcactgc atccatgagc atgcccacgg gattcggcac tcctgctccc 1680
tacagtcttc ccaccagctt tagtggcagc tttcagcagc ctgcctttcc agcccaagca 1740
gctttccctc aacagacagc tttttctcaa cagcccaatg gtgcaggttt tgcagcattt 1800
ggacaaacaa agccagtagt aacccctttt ggtcaagttg cagctgctgg agtatctagt 1860
aatcctttta tgactggtgc accaacagga caatttccaa caggaagctc atcaaccaat 1920
cctttcttat agccttatat agacaattta ctggaacgaa cttttatgtg gtcacattac 1980
atctctccac ctcttgcact gttgtcttgt ttcactgatc ttagctttaa acacaagaga 2040
agtctttaaa aagcctgcat tgtgtattaa acaccaggta atatgtgcaa aaccgagggc 2100
tccagtaaca ccttctaacc tgtgaattgg cagaaaaggg tagcggtatc atgtatatta 2160
aaattggcta atattaagtt attgcagata ccacattcat tatgctgcag tactgtacat 2220
atttttctta gaaattagct atttgtgcat atcagtattt gtaactttaa cacattgtta 2280
tgtgagaaat gttactgggg aaatagatca gccactttta aggtgctgtc atatatcttg 2340
gaatgaatga cctaaaatca ttttaaccat tgctactgga aagtaacaga gtcaaaattg 2400
gaaggtttta ttcattcttg aatttttcct ttctaaagag ctcttctatt tatacatgcc 2460
taaattcttt taaaatgtag agggatacct gtctgcataa taaagctgat catgttttgc 2520
tacagtttgc aggtgaaaaa aaataaatat tataaaataa aaaaaaaaaa aaagaaaaaa 2580
aaaa 2584
<210>82
<211>2115
<212>DNA
<213>人
<400>82
gaaatgaacc tctcttattg atttttattg gcctagagcc aggagtactg cattcagttg 60
actttcaggg taaaaagaaa acagtcctgg ttgttgtcat cataaacata tggaccagtg 120
tgatggtgaa atgagatgag gctccgcaat ggaactgtag ccactgcttt agcatttatc 180
acttccttcc ttactttgtc ttggtatact acatggcaaa atgggaaaga aaaactgatt 240
gcttatcaac gagaattcct tgctttgaaa gaacgtcttc gaatagctga acacagaatc 300
tcacagcgct cttctgaatt aaatacgatt gtgcaacagt tcaagcgtgt aggagcagaa 360
acaaatggaa gtaaggatgc gttgaataag ttttcagata ataccctaaa gctgttaaag 420
gagttaacaa gcaaaaaatc tcttcaagtg ccaagtattt attatcattt gcctcattta 480
ttgaaaaatg aaggaagtct tcaacctgct gtacagattg gcaacggaag aacaggagtt 540
tcaatagtca tgggcattcc cacagtgaag agagaagtta aatcttacct catagaaact 600
cttcattccc ttattgataa cctgtatcct gaagagaagt tggactgtgt tatagtagtc 660
ttcataggag agacagatat tgattatgta catggtgttg tagccaacct ggagaaagaa 720
ttttctaaag aaatcagttc tggcttggtg gaagtcatat caccccctga aagctattat 780
cctgacttga caaacctaaa ggagacattt ggagactcca aagaaagagt aagatggaga 840
acaaagcaaa acctagatta ctgttttcta atgatgtatg ctcaagaaaa gggcatatat 900
tacattcagc ttgaagatga tattattgtc aaacaaaatt attttaatac cataaaaaat 960
tttgcacttc aactttcttc tgaggaatgg atgattctag agttttccca gctgggcttc 1020
ttggtaaaa tgtttcaagc gccggatctt actctgattg tagaattcat attcatgttt 1080
tacaaggaga aacccattga ttggctcctg gaccatattc tctgggtgaa agtctgcaac 1140
cctgaaaaag atgcaaaaca ttgtgataga cagaaagcaa atctgcgaat tcgcttcaga 1200
ccttcccttt tccaacatgt tggtctgcac tcatcactat caggaaaaat ccaaaaactc 1260
acggataaag attatatgaa accattactt cttaaaatcc atgtaaaccc acctgcggag 1320
gtatctactt ccttgaaggt ctaccaaggg catacgctgg agaaaactta catgggagag 1380
gatttcttct gggctatcac accgatagct ggagactaca tcttgtttaa atttgataaa 1440
ccagtcaatg tagaaagtta tttgttccat agcggcaacc aagaacatcc tggagatatt 1500
ctgctaaaca caactgtgga agttttgcct tttaagagtg aaggtttgga aataagcaaa 1560
gaaaccaaag acaaacgatt agaagatggc tatttcagaa taggaaaatt tgagaatggt 1620
gttgcagaag gaatggtgga tccaagtctc aatcccattt cagcctttcg actttcagtt 1680
attcagaatt ctgctgtttg ggccattctt aatgagattc atattaaaaa agccaccaac 1740
tgatcatctg agaaaccaac acattttttc ctgtgaattt gttaattaaa gatagttaag 1800
catgtatctt ttttttattt ctacttgaac actacctctt gtgaagtcta ctgtagataa 1860
gacgattgtc atttccactt ggaaagtgaa tctcccataa taattgtatt tgtttgaaac 1920
taagctgtcc tcagatttta acttgactca aacatttttc aattatgaca gcctgttaat 1980
atgacttgta ctattttggt attatactaa tacataagag ttgtacatat tgttacattc 2040
tttaaatttg agaaaaacta atgttacata cattttatga agggggtact tttgaggttc 2100
acttatttta ctatt 2115
<210>83
<211>1635
<212>DNA
<213>人
<400>83
gggggtggcg gggacgcgag tggcggccgc ggggccccgg acaagggtcc gcagagctgc 60
agccttcgag ggccagccct ctccgagtcc ggggctgggt cccaccagtg acaaggcggc 120
agccccgcgc acaccaaaga gaaagcggct gtggcggcag cggcagcccc agccatgctg 180
tgttatgtga cgaggccgga cgcggtgctg atggaggtgg aggtggaggc gaaagccaac 240
ggcgaggact gcctcaacca ggtgtgcagg cgactgggaa tcatagaagt tgactatttt 300
ggactgcaat ttacgggtag caaaggtgaa agtttatggc taaacctgag aaaccggatc 360
tcccagcaga tggatgggct agccccttac aggcttaaac ttagagtcaa gttcttcgtg 420
gagcctcatc tcatcttaca ggagcagact aggcatatct ttttcttgca catcaaggag 480
gccctcttgg caggccacct cttgtgttcc ccagagcagg cagtggaact cagtgccctc 540
ctggcccaga ccaagtttgg agactacaac cagaacactg ccaagtataa ctatgaggag 600
ctctgtgcca aggagctctc ctctgccacc ttgaacagca ttgttgcaaa acataaggag 660
ttggagggga ccagccaggc ttcagctgaa taccaagttt tgcagattgt gtcggcaatg 720
gaaaactatg gcatagaatg gcattctgtg cgggatagcg aagggcagag actgctcatt 780
ggggttggac ctgaaggaat ctcaatttgt aaagatgact ttagcccaat taataggata 840
gcttatcctg tggtgcagat ggccacccag tcaggaaaga atgtatattt gacggtcacc 900
aaggaatctg ggaacagcat cgtgctcttg tttaaaatga tcagcaccag ggcggccagc 960
gggctctacc gagcgataac agagacgcac gcattctaca ggtgtgacac agtgaccagc 1020
gccgtgatga tgcagtatag ccgtgacttg aagggccact tggcatctct gtttctgaat 1080
gaaaacatta accttggcaa gaaatatgtc tttgatatta aaagaacatc aaaggaggtg 1140
tatgaccatg ccaggagggc tctgtacaat gctggcgttg tggacctcgt ttcaagaagc 1200
aaccagagcc cttcacactc gcctctgaag tcctcagaaa gcagcatgaa ctgcagcagc 1260
tgcgagggcc tcagctgcca gcagacccgg gtgctgcagg agaagctacg caagctgaag 1320
gaagccatgc tgtgcatggt gtgctgcgag gaggagatca actccacctt ctgtccctgt 1380
ggccacactg tgtgctgtga gagctgcgcc gcccagctac agtcatgtcc cgtctgcagg 1440
tcgcgtgtgg agcatgtcca gcacgtctat ctgccaacgc acaccagtct tctcaatctg 1500
actgtaatct aatctgttgt gcttttgttg gacttggcat gtttccatga actgcactat 1560
tataaactat taaaatgata gatgttggag aaagtaatta ttccaacacc catctgccca 1620
tgcgatgtta aaaaa 1635
<210>84
<211>2118
<212>DNA
<213>人
<400>84
ctgtgaagat ggcgctctcc agggtgtgct gggctcggtc ggctgtgtgg ggctcggcag 60
tcacccctgg acattttgtc acccggaggc tgcaacttgg tcgctctggc ctggcttggg 120
gggcccctcg gtcttcaaag cttcaccttt ctccaaaggc agatgtgaag aacttgatgt 180
cttatgtggt aaccaagaca aaagcgatta atgggaaata ccatcgtttc ttgggtcgtc 240
atttcccccg cttctatatc ctgtacacaa tcttcatgaa aggattgcag atgttatggg 300
ctgatgccaa aaaggctaga agaataaaga caaatatgtg gaagcacaat ataaagtttc 360
atcaacttcc ataccgggag atggagcatt tgagacagtt ccgccaagac gtcaccaagt 420
gtcttttcct aggtattatt tccattccac cttttgccaa ctacctggtc ttcttgctaa 480
tgtacctgtt tcccaggcaa ctactgatca ggcatttctg gaccccaaaa caacaaactg 540
atttcttaga tatctatcat gctttccgga agcagtccca cccagaaatt attagttatt 600
tagaaaaggt catccctctc atttctgatg caggactccg gtggcgtctg acagatctgt 660
gcaccaagat acagcgtggt acccacccag caatacatga tatcttggct ctgagagagt 720
gtttctctaa ccatcctctg ggcatgaacc aactccaggc tttgcacgtg aaagccttga 780
gccgggccat gcttctcaca tcttacctgc ctcctccctt gttgagacat cgtttgaaga 840
ctcatacaac tgtgattcac caactggaca aggctttggc aaagctgggg attggccagc 900
tgactgctca ggaagtaaaa tcggcttgtt atctccgtgg cctgaattct acgcatattg 960
gtgaagatag gtgtcgaact tggctgggag aatggctgca gatttcctgc agcctgaaag 1020
aagctgagct gtctctcttg ctgcacaacg tggtcctgct ctccaccaac taccttggga 1080
caaggcgctg aatgaaccat ggagcggatg gcattgtcct gcagtcgtat agtatagcag 1140
tgcaggaaca aacagcactt gccagcaaag tctgtgtgta ctgttaagtg tgtgggaggc 1200
agagagagga gcaggggcca tgggcttcac agcatggcac acctgtggga actgcagaca 1260
ttcctctcac agctagaact gaaacaaacc ctcttgctag gggtggtccg tgtgaggtgt 1320
catcctgtcc ccctcataat tactaatagc tggaactggc agcagcctct actgggcttt 1380
tactgtgatg tgttcagttc atgtcctagg aagtcagctt ttgccccagg tgggaatcct 1440
tatttggctt aggactgatc cacttccatg ttacttacat ctgtgggttt ttgttgttgc 1500
tgttagaaaa tttttggctg gtgaaaacag cactcctttg gctggagcac ttgtgtccat 1560
gcatgtactt gggtgtttcc ctccatcctt tctgatatga ccaaaaatca agttgttttg 1620
ttttttgtca ccttcactgg catgggctaa ccacttcttt ttcaaaccct ctgaacacct 1680
ttttctgatg ggtaacttgc aggaatattc tattggaaaa gataacagga agtacaagtg 1740
cttcttgacc ccttcctcaa tgtttctagc cttcactctc cattgtcttt tctgggctgt 1800
attacagccc tctgtggatc ttcaactctg ctgcctccac tgtgatgcag cagtccaact 1860
gtaactgaca gtggctgcct tctctgggcc atggatcaca cctgtaaggt actaattact 1920
gcccagcctg gggagatcag gagaggtctg catagttagt aagttgggtt tagcttttgt 1980
gtgtgcatca gtgacttaga gttctgtaat aacttattgt aaatgcatga agcactgttt 2040
ttaaacccaa gtaaagactg cttgaaacct gttgatggaa aaaaaaaaaa aaaaaaaaaa 2100
aaaaaaaaaa aaaaaaaa 2118
<210>85
<211>4221
<212>DNA
<213>人
<400>85
cgataacgat ttgtgttgtg agaggcgcaa gctgcgattt ctgctgaact tggaggcatt 60
tctacgactt ttctctcagc tgaggctttt cctccgaccc tgatgctctt caattcggtg 120
ctccgccagc cccagcttgg cgtcctgaga aatggatggt cttcacaata ccctcttcaa 180
tcccttctga ctggttatca gtgcagtggt aatgatgaac acacttctta tggagaaaca 240
ggagtcccag ttcctccttt tggatgtacc ttctcttctg ctcccaatat ggaacatgta 300
ctagcagttg ccaatgaaga aggctttgtt cgattgtata acacagaatc acaaagtttc 360
agaaagaagt gcttcaaaga atggatggct cactggaatg ccgtctttga cctggcctgg 420
gttcctggtg aacttaaact tgttacagca gcaggtgatc aaacagccaa attttgggac 480
gtaaaagctg gtgagctgat tggaacatgc aaaggtcatc aatgcagcct caagtcagtt 540
gccttttcta agtttgagaa agctgtattc tgtacgggtg gaagagatgg caacattatg 600
gtctgggata ccaggtgcaa caaaaaagat gggttttata ggcaagtgaa tcaaatcagt 660
ggagctcaca atacctcaga caagcaaacc ccttcaaaac ccaagaagaa acagaattca 720
aaaggacttg ctccttctgt ggatttccag caaagtgtta ctgtggtcct ctttcaagac 780
gagaatacct tagtctcagc aggagctgtg gatgggataa tcaaagtatg ggatttacgt 840
aagaattata ctgcttatcg acaagaaccc atagcatcca agtctttcct gtacccaggt 900
agcagcactc gaaaacttgg atattcaagt ctgattttgg attccactgg ctctacttta 960
tttgctaatt gcacagacga taacatctac atgtttaata tgactgggtt gaagacttct 1020
ccagtggcta ttttcaatgg acaccagaac tctacctttt atgtaaaatc cagccttagt 1080
ccagatgacc agtttttagt cagtggctca agtgatgaag ctgcctacat atggaaggtc 1140
tccacaccct ggcaacctcc tactgtgctc ctgggtcatt ctcaagaggt cacgtctgtg 1200
tgctggtgtc catctgactt cacaaagatt gctacctgtt ctgatgacaa tacactaaaa 1260
atctggcgct tgaatagagg cttagaggag aaaccaggag gtgataaact ttccacggtg 1320
ggttgggcct ctcagaagaa aaaagagtca agacctggcc tagtaacagt aacgagtagc 1380
cagagtactc ctgccaaagc ccccagggta aagtgcaatc catccaattc ttccccgtca 1440
tccgcagctt gtgccccaag ctgtgctgga gacctccctc ttccttcaaa tactcctacg 1500
ttctctatta aaacctctcc tgccaaggcc cggtctccca tcaacagaag aggctctgtc 1560
tcctccgtct ctcccaagcc accttcatct ttcaagatgt cgattagaaa ctgggtgacc 1620
cgaacacctt cctcatcacc acccatcact ccacctgctt cggagaccaa gatcatgtct 1680
ccgagaaaag cccttattcc tgtgagccag aagtcatccc aagcagaggc ttgctctgag 1740
tctagaaata gagtaaagag gaggctagac tcaagctgtc tggagagtgt gaaacaaaag 1800
tgtgtgaaga gttgtaactg tgtgactgag cttgatggcc aagttgaaaa tcttcatttg 1860
gatctgtgct gccttgctgg taaccaggaa gaccttagta aggactctct aggtcctacc 1920
aaatcaagca aaattgaagg agctggtacc agtatctcag agcctccgtc tcctatcagt 1980
ccgtatgctt cagaaagctg tggaacgcta cctcttcctt tgagaccttg tggagaaggg 2040
tctgaaatgg taggcaaaga gaatagttcc ccagagaata aaaactggtt gttggccatg 2100
gcagccaaac ggaaggctga gaatccatct ccacgaagtc cgtcatccca gacacccaat 2160
tccaggagac agagcggaaa gacattgcca agcccggtca ccatcacgcc cagctccatg 2220
aggaaaatct gcacatactt ccatagaaag tcccaggagg acttctgtgg tcctgaacac 2280
tcaacagaat tatagattct aatctgagtg agttactgag ctttggtcca ctaaaacaag 2340
ctgagctttg gtccactaaa acaagatgaa aaatacaaga gtgactctat aactctggtc 2400
tttaagaaag ctgccttttc atttttagac aaaatctttt caacgctgaa atgtacctaa 2460
tctggttcta ctaccataat gtatatgcag cttcccgagg atgaatgctg tgtttaaatt 2520
tcataaagta aatttgtcac tctagcattt tgaatgaata gtcttcactt tttaaattat 2580
tcatcttctc tataataatg acatcccagt tcatggaggc aaaaaacaag tttcttgtta 2640
tcctgaaact ttctatgctc agtggaaagt atctgccagc cacagcatga ggcctgtgaa 2700
ggctgactga gaaatcctct gctgaagacc cctggttctg ttctgcctcc aacatgtata 2760
attttatttg aaatacataa tcttttcact atgcttttgt ggggtttttt ttaagtatgt 2820
gtaaaaatgt gatgctcaga taagtacatt tatatcagtt cagtgttaaa atgcagtctc 2880
ttgagttaaa gtcatcttta ttttaaatgc agtgataaat gtcaactctt cggagaaact 2940
aggagaacaa caacagaaag ctgtgtttgt cttttttctc tcaaatatat ctcccgtatg 3000
agatttcagg tccccatgtt ttcaccaagc aatctgctat gtcagccaac ccaacatcac 3060
tttctacagg aggttatgat ttttgccatt tactagagga agatgtttta tgaaatcaat 3120
ttggggtttg aattcaggtg cagtcatcag ttctttaggg gctgcaatgt tttaaaaaaa 3180
ataagtcatc agattttaag aaaaaagtga tgatttctta ttgatatttt tgtaacagaa 3240
tatagctctt aactgaaaat ccagaaccag aaacataaat cttgagtttc ttttcatgta 3300
cataaaaagc aatagccttt tagtatagat agccctgagc caaaaagtaa tagaattttc 3360
tctagatatt taatacagag agtgtataga ctgactctaa gttaataatg tgcaaaatat 3420
cttaaacatc cctcccctta ttcaacaatt atgtatcagt gatcttgaac cattgtttta 3480
tatttttcac ctttgtaacc tcatggaaag aggctttaca tactttctat gtactattta 3540
cttagaaggg agcccccttc cagtcatgaa acttcatttg ttttatccat atccctgagg 3600
actgtgtaga ctttatgtca gttctgtgta gactttatgt cagtttttgt cattatttga 3660
aaatctattc tgacaacttt ttaattcctt tgatcttata agttaaagct gtaacaactg 3720
aaattgcatg gatcaagtaa gcatagtttt atccagggag aaaaataaaa ggaagccata 3780
gaattgctct ggtcaaaacc aagcacacca tagccttaac tgaatattta ggaaatctgc 3840
ctaatctgct tatatttggt gtttgttttt tgactgttgg gctttgggaa gatgttattt 3900
atgaccaata tctgccagta acgctgttta tctcacttgc tttgaaagcc aatgggggaa 3960
aaaaatccat gaaaaaaaaa agattgataa agtagatgat tttgtttgta tccctaccca 4020
tctcctggca gccctactga gtgaaattgg gatacatttg gctgtcagaa attataccga 4080
gtctactggg tataacatgt ctcacttgga aagctagtac ttttaaatgg gtgccaaagg 4140
tcaactgtaa tgagataatt atccctgcct gtgtccatgt cagactttga gctgatcctg 4200
aataataaag ccttttacct t 4221
<210>86
<211>867
<212>DNA
<213>人
<400>86
cgtttcagcg tggcggcgct ggtgctggcg ttggccctgg aggacggccc cgagtgatgg 60
ctggcgcctg cctcccgggt gtctcccggg tacagatgga gtcgtcccgc ggccgccggc 120
ggcaaggtcg gcagctgcga ggccaagaga gaccccagga cacacacagc tgcctcccgg 180
tgcgagaaga agaccccggc ttgagagtga gatggcgttt aatgattgct tcagtttgaa 240
ctaccctggc aacccctgcc caggggactt gatcgaagtg ttccgtcctg gctatcagca 300
ctgggccctg tacttgggtg atggttacgt tatcaacata gcacctgtag atggcattcc 360
tgcgtccttt acaagcgcca agtctgtatt cagcagtaag gccctggtga aaatgcagct 420
cttgaaggat gttgtgggaa atgacacata cagaataaac aataaatacg atgaaacgta 480
cccccctctc cctgtggaag aaatcataaa gcggtcagag tttgtaattg gacaggaggt 540
ggcctataac ttacttgtca acaactgtga acattttgtg acattgcttc gctatggaga 600
aggagtttca gagcaggcca accgagcgat aagtaccgtt gagtttgtga cagctgctgt 660
tggtgtcttc tcattcctgg gcttgtttcc aaaaggacaa agagcaaaat actattaaca 720
atttaccaaa gagatattga tattgaagga atttgggagg aggaaaagaa acctggggtg 780
aatacttatt ttcagtgcat cattactgtt ccagattcct atgatggatg gcagactctt 840
taataaattg cttactgata ttatctt 867
<210>87
<211>561
<212>DNA
<213>人
<220>
<221>misc_特征
<222>(534)..(534)
<223>任意碱基
<400>87
tttttttttc aaattttatt ttttgtactt ttattgaaaa ggtacattta aaaaaataca 60
cagacatttt accatttaca ggttgcagat atagatgctc taaaagagtc cactctattt 120
tgttgttcta tgataactct tgcccctgat atcacaaaca ttccagtctt gttgatatcg 180
gcttaaaaag gggggcatgg gagcatgacc tgcaatatat tcagcgaaca gaaagacaaa 240
ttgttcaatt ataaattttt ttatcttctg tacattattg cattagggag ccacaaaatt 300
atgtagcatc attacaaatg aaaacaggtt aaaaatgaag aagatactta tatagaaata 360
catggattca ttgtcttctt gcagaatgca caagaggtgc aaaaatgtgc aatttaggaa 420
gctctttttc tgtttgtata cgtttgctta gcaacacaaa ccagtgagga agctacaaaa 480
taagttaaac aaaaatagca aacaggtagt aattatagct atgttatatg gctntctatt 540
tcatttaaat atctccaaat a 561
<210>88
<211>471
<212>DNA
<213>人
<400>88
tttcatgaat aattttattt ttattttggt catgactttt taaaattaat ggaaagtctc 60
agtctgctca aatgataaac caaaaaatgg ggtcatgaag caaattcagt ctttgcattt 120
cttcaacaac caactcacat ttctctgctc cttgactcag aggctggaca tgtgctaaca 180
gcttttttgc ttctgtatat ccttaatagg atggcagaat cccggtgtta aaagaatctt 240
aaagtcagcc gtgtcaccat gggacctcga ttagcaaaca gatgtagaca ttccttccaa 300
attcagtcaa agaaaaaact ctaataccag cagccatgtt cagggtgtgc acgacatgct 360
gagcgcttgg gatacatccc cttgtttaat tctcacagaa actttgtgag acaagtacta 420
taatccctgt ttaacagatg ggcaaactga ggtttggaaa aacactcatt t 471
<210>89
<211>727
<212>DNA
<213>人
<400>89
taaaatatta ccttttattt tctcaggcac acaagtgatt tggataccaa ttatcaagac 60
attttactga tttcccttta gaatgatcta ttttaaatct tcagccacct tagaaaaagt 120
ttgcagcaat cactttgcaa ttcataagta tcaggttaga atttagttgt ggaataagtt 180
aacagtttat gttcaatatg tgaggttatt tgaactcctg agttttaaat atcctgtgga 240
acagtgattc ctctcccttc taatggcttt tcagattaaa gcaatgactt taaaaagatt 300
acatcctaaa tacttgatta caacagaaat cgaccaatct aaaaatcaga tagtgttata 360
ctgaacatca ttctgatata atgagtagcc tctggctgaa acaaaattcc accaccaagg 420
ccatcaacca ggttagtact gtttttcctg gggtctatgt aaactctcct tttctctgca 480
aatgctgctt ggctgtgaac agcatggatt tacctgcacc aatgtggcac acacctagca 540
actttctcaa gcattctaaa gatatcccca gagctacaat attgacatat gcacagcact 600
ttctctagac agtccaatca gcgtgcacat cacacacaca gaatgctggg atatgctata 660
ctgcacactt agtacacagg tggaatagag tacaatgact aaagctcaca gaaaatgttt 720
tagtctt 727
<210>90
<211>460
<212>DNA
<213>人
<400>90
tttttgatat aaagggcttt tattttcttt acagttttct gtattttcca aatttctaca 60
taaacataca cataaaagtc ataaaaatgt ccctcaaaat gacactccct ccaatgcagg 120
gagtgaggag gtgtgtgctg ggacgccaca gggtggctgc tgcagctaat ccctgtgcag 180
gtgcagccac tgctacactc cagcgtctga ggcccctctg cactggcagt gttagaatgg 240
ctgtctgaga gccaaggctg ttcacccgag cagagagtca tggagctggt acaggcagga 300
gccaaggtaa gcactaggct ggtgtgtgcc ctccaggggg caccctcctt gaagcaggcc 360
ctccaaggta ctcgccccct gaggcagccg ataacagccg gaagccttcc cctgggggga 420
cctggccatt tgtggagcag ggaaaggctc cactgccagt 460
<210>91
<211>392
<212>DNA
<213>人
<400>91
tttttttttt tttttttgag ttgctgaaaa gtttactttt gagttttaaa ctgtactttg 60
aaaactatat tgtgaactgt gttgacatga ggaaaggctg ggctccctga aaacatccag 120
ttccacagca gggcgggccc aagcccagcc aatccccagg caatgcaggg cagggatccc 180
acctggtata agtacgggca gagggcagag ccaggctgta tcgaggggcg gcgctgggac 240
cctcctcgcc cagaattcct actcatcccc agcacagaag tgctctgtag ggccagctga 300
ggacaccccg gttcactgag ggtggcccac agtaagtcgc cgtctggcag taagttagct 360
ctgcaggtgt ggaccccaag accacacacg gc 392
<210>92
<211>496
<212>DNA
<213>人
<400>92
ttttttgtat ttttctcaat ataatgttgc aagatgtcat tatattctca ttacccataa 60
cttcccatcc aaatcttaat ggcacatttg atattttttc aaatggcttt gagatataat 120
tcacatacca cacaattcat gtatctaaag tatacagttc tgtagttctg tggttgttgg 180
ttacatccac cagactgagg gctccctgag ggttggtgcc tcagctttcc cttcacttac 240
tcattcacca aacattcagc gcctactgag tactggggtt atgatggcca acaggagaga 300
cagtctctgc ctactgtttg gtgggggtgg agtacttagt aaccgtcgtc attattgagt 360
gcttacctgt gctgggcaca gtgctgctac tgggtgactg tgtccccagg gctgtcccag 420
gctgggggtc tggaggagta gttatcagtt gaactgagtt aatccacagt ggaaggtaac 480
ccactccctg ccctag 496
<210>93
<211>472
<212>DNA
<213>人
<400>93
ttaacacaaa agcttttact tggaaactgg caaatactgg actagaatac tgacatgctc 60
acgctctggc gggagctcgg atgcagaagc tattgcacaa agcccctctg attgccttgc 120
tcctctttgg catgtatcag cagagcccca agggccaatt gcccacaggt ggggactgtt 180
ctccatcaag gtatggggac ccctacttcc ttgttttgtt aaaaagtgca ggtaggcgaa 240
gaaagcccag gcagttgacc cagtctttga aacagctgac tccccagagc tggggccagg 300
ggagcctggt cttgaggggt aagggctgca gggccaggct gatggcctgt gtcatggcat 360
tggccatctc ctctccagct tctcctcagc catcgcccgt ccgtcatggt ggtgtcggct 420
gcacctggac cttcctgcct ctccgctcag ggcagcagca gtgagtgcag ca 472
<210>94
<211>585
<212>DNA
<213>人
<400>94
tttttatatt atagtaaatt tatttggtat aattacatat taacattatt tacaatgcta 60
atttttttat ttataaagta tctttatatg gacaaaaaga tacaaactgt tatcatttta 120
agtacaaagt atttctagaa atacattata agccattaaa aaaaaaaacg atatttcaag 180
attggttctt acatgctatg accaactcat atgaaagagc aagttgctcc cccttcattc 240
cttcccccaa ctccaaaggg aaaggaattt gatatttagg ctttaaaaaa tttcctacta 300
cctttatctt ttaaaaaacc ctactcaaaa caactatctc ttataaggga aaatatcata 360
gataagattt tcctttagaa aatgacatta aaagtggcat gagccctaga atgatatgtg 420
tattagaggc acttaaaaaa aatcagaagg gatccatagg aaggaattta attcagcaaa 480
tactgagtgt ccactgcatg caaggtaccc tgccagaaat ctcaaatgag taagttgtcc 540
ttagggatag aaggtgctaa gcatcatgca aaagatatga actga 585
<210>95
<211>400
<212>DNA
<213>人
<400>95
ttattgtttt ttaaaaatac aattttgaaa tttattgttg aaaatggaca catggaacaa 60
accaaacctt gttttatcat gtaattttca gaaaatatgt gatccataaa gattaaaaga 120
aagttgtatt aagtctggca gctttagtat taacttgaaa taaaatatgg caagctttcc 180
acgtcctcct ttatttccac aatccatatg tacgagctag attccagtca gaacttccac 240
aaatacttca ctctttggta gcagcggtta taaattacgc ctttgctaat ttgcgttgtt 300
cccaaccagg agaaacatta ccacaaaaaa agtcagtttc atcctgcagt gttcccgcag 360
caaccatatt aaagctgaag aataaagctc ctttgtagta 400
<210>96
<211>461
<212>DNA
<213>人
<400>96
ttatgccatg aattcctttt tactgaaata ccgtaggact cactaccaca ataagtactt 60
aagctgaaag agtttctaat gggagccaag taaattcagc tctccactgt gcaaagcatc 120
ttgtcatttc tataataaaa gtctttccat gttcagtcca ctttggctct ggaacctgga 180
tgagtcatgc ttggggccca gggtgcctgt gaggatgctg catgagaatt tcagctgtgg 240
tggcagtggc tgggagtccc actgactcag ggggaggcca ggcgagatga gctggaactt 300
ttaggggaga gctggcactt agggacatca ttgattgtgc ttttcttagc ctagttctgt 360
cctgcaattt atttttctta tcatgtgact gtcggctgaa gtctggggtt atttggtttc 420
tttttcttct tccttgctgg acagtctcca tggggtcacg g 461
<210>97
<211>542
<212>DNA
<213>人
<400>97
taaatccagt aaagcatagt actagattca tcatacttgt acaatacaac gggcgacatg 60
aaaatggcaa aggctctcct ttttgtgaac aatttaatac aactggtggt ccaataactc 120
tacaatcagc cttgtagagg tcattaaaga cagaatcctg aaagtccgtg actacaaata 180
cattttcaaa ttccggagaa tccaaacctt caaattcttc cactgactcc atctttacaa 240
agcccacttt aatgtccttt aaggctttta taagttcttc ttgttttcca gcttcttgaa 300
ccaatatcac tcttgtttca atctgaggca tctcttcttc tacatatgaa gtagatccaa 360
taagtaagtt ttccttggaa atctcagtaa ctttagaatc aaaaatggaa gagtctgcca 420
agctagtcct cccagtagtg gatgttaata cactattttc agccatgatt tgtattcttc 480
taaatcagca ctctcaaaaa agccctagga gttccacctc ttcaaacgcc gactcctctc 540
ac 542
<210>98
<211>1017
<212>DNA
<213>人
<400>98
atgggcacct ggcttctggc ctgcacctgc gtctgcacct gtgtctgctc gggagtctct 60
gtctcagggg atggacgagg gccaagggct ggaacctcca cctgcctcac caacaacatt 120
ctcaggattg attgccactg gtctgcccca gagctgggtc agggctccag ccccgggctc 180
cccttcatca gccccgtggt gctgacacat gcccttttca gcaaccaggc tgctggtggc 240
acacagaagt gcatctggca gggcagtgag tgcactgtag tgttgccgcc caaggcagca 300
ctcctgccat ctgacaattt catcatcact ttctaccact gcatgtccgg gagggatcag 360
agcacgtcag ctcgccactg catcctgacc tggagcctca gtcctgcctt ggagtcaatg 420
accacacttc tcagctatga gctggacttc aagaggcagg aagaggcctg ggagcgggcc 480
cagcacaggg atcacattgt cggggtgacc tggctcatac ttgaagcctt tgagctggac 540
cctggcttta tccttgaggc caggctgcgt gtccagacgg ccatgctggg ggatgacggg 600
gcacaggagg agcgagggga gccagcccat gggaagagtg aggcccagga gtgtggttca 660
cacaaggtcc ttcagcaggt gacacaaacc tccaaggccc atcacaaggt ccttcagcag 720
atgacacaaa cctccaaggc tcatcacaaa ccttccactt tggcccaggg cactaaaggg 780
cgcacttttg ccagccctgg gcccttcctg cccacggacc ctctgatccc accctggggg 840
tggccaggca acacctttgt tgctgtgtcc atctttctcc tgctgactgg cccgacctac 900
ctcctgttca agctgtcgcc cagactcctc actttgggca aaggacaaga agcaactcgg 960
atgggggccc acagggctgg tgtgctgctg agccaggact gtgctggcac ccgatga 1017
<210>99
<211>1099
<212>DNA
<213>人
<400>99
agccccaagc ttaccacctg cacccggaga gctgtgtcac catgtgggtc ccggttgtct 60
tcctcaccct gtccgtgacg tggattggtg agaggggcca tggttggggg gatgcaggag 120
agggagccag ccctgactgt caagctgagg ctctttcccc cccaacccag caccccagcc 180
cagacaggga gctgggctct tttctgtctc tcccagcccc actccaagcc cataccccca 240
gcccctccat attgcaacag tcctcactcc cacaccaggt ccccgctccc tcccacttac 300
cccagaactt tctccccatt gcccagccag ctccctgctc ccagctgctt tactaaaggg 360
gaagttcctg ggcatctccg tgtttctctt tgtggggctc aaaacctcca aggacctctc 420
tcaatgccat tggttccttg gaccgtatca ctggtccacc tcctgagccc ctcaatccta 480
tcacagtcta ctgacttttc ccattcagct gtgagtgccc aaccctatcc cagagacctt 540
gatgcttggc ctcccaatct tgccctagga tacccagatg ccaaccagac acctccttct 600
tcctagccag gctatctggc ctgagacaac aaatgggtcc ctcagtctgg caatgggact 660
ctgagaactc ctcattccct gactcttagc cccagactct tcattcagtg gcccacattt 720
tccttaggaa aaacatgagc atccccagcc acaactgcca gctctctgat tccccaaatc 780
tgcatccttt tcaaaaccta aaaacaaaaa gaaaaacaaa taaaacaaaa ccaactcaga 840
ccagaactgt tttctcaacc tgggacttcc taaactttcc aaaaccttcc tcttccagca 900
actgaacctc gccataaggc acttatccct ggttcctagc accccttatc ccctcagaat 960
ccacaacttg taccaagttt cccttctccc agtccaagac cccaaatcac cacaaaggac 1020
ccaatcccca gactcaagat atggtctggg cgctgtcttg tgtctcctac cctgatccct 1080
gggttcaact ctgctccca 1099
<210>100
<211>1095
<212>DNA
<213>人
<400>100
ccaagcttac cacctgcacc cggagagctg tgtcaccatg tgggtcccgg ttgtcttcct 60
caccctgtcc gtgacgtgga ttggtgagag gggccatggt tggggggatg caggagaggg 120
agccagccct gactgtcaag ctgaggctct ttccccccca acccagcacc ccagcccaga 180
cagggagctg ggctcttttc tgtctctccc agccccactt caagcccata cccccagccc 240
ctccatattg caacagtcct cactcccaca ccaggtcccc gctccctccc acttacccca 300
gaactttctc cccattgccc agccagctcc ctgctcccag ctgctttact aaaggggaag 360
ttcctgggca tctccgtgtt tctctttgtg ggg ctcaaa cctccaagga cctctctcaa 420
tgccattggt tccttggacc gtatcactgg tccatctcct gagcccctca atcctatcac 480
agtctactga cttttcccat tcagctgtga gtgtccaacc ctatcccaga gaccttgatg 540
cttggcctcc caatcttgcc ctaggatacc cagatgccaa ccagacacct ccttcttcct 600
agccaggcta tctggcctga gacaacaaat gggtccctca gtctggcaat gggactctga 660
gaactcctca ttccctgact cttagcccca gactcttcat tcagtggccc acattttcct 720
taggaaaaac atgagcatcc ccagccacaa ctgccagctc tctgagtccc caaatctgca 780
tccttttcaa aacctaaaaa caaaaagaaa aacaaataaa acaaaaccaa ctcagaccag 840
aactgttttc tcaacctggg acttcctaaa ctttccaaaa ccttcctctt ccagcaactg 900
aacctcgcca taaggcactt atccctggtt cctagcaccc cttatcccct cagaatccac 960
aacttgtacc aagtttccct tctcccagtc caagacccca aatcaccaca aaggacccaa 1020
tccccagact caagatatgg tctgggcgct gtcttgtgtc tcctaccctg atccctgggt 1080
tcaactctgc tccca 1095
Claims (26)
1.一种诊断癌症的方法,包括鉴定基因组合物中每一个基因的差异性调节(相对于同一个基因在正常人群中的表达),该组合物中的基因选自Seq IDNo.1-30、SEQ ID No.32、Seq ID No.34和Seq ID No.98。
2.权利要求1的方法,其中被调节基因的表达至少有2倍的差异。
3.权利要求1的方法,其中表示差异性调节的p值小于0.05。
4.一种诊断癌症的方法,包括鉴定基因组合物中每一个基因的差异性调节(相对于同一个基因在正常人群中的表达方式),该组合物中的基因选自SeqID No.32-67、Seq ID No.69和Seq ID No.98-100。
5.权利要求4的方法,其中被调节基因的表达至少有2倍的差异。
6.权利要求4的方法,其中表示差异性调节的p值小于0.05。
7.一种诊断组合物,包括基因组合物的分离的核酸序列、它们的互补序列或其部分,所述基因选自Seq ID No.1-30、Seq ID No.32、Seq ID No.34和SeqID No.98。
8.权利要求7所述的诊断组合物,其存在于适于鉴定其中所含基因的差异性表达的矩阵中。
9.权利要求8所述的诊断组合物,其中所说的矩阵是微阵列。
10.权利要求9所述的诊断组合物,其中所述的微阵列是cDNA微阵列。
11.权利要求9所述的诊断组合物,其中所述的微阵列是寡聚核苷酸微阵列。
12.一种诊断组合物,包括基因组合物的分离的核酸序列、它们的互补序列或者其部分,所述基因选自Seq ID No.32-67、Seq ID No.69和Seq ID No.98-100。
13.权利要求12所述的诊断组合物,其存在于适于鉴定其中所含基因的差异性表达的矩阵中。
14.权利要求13所述的诊断组合物,其中所说的矩阵是微阵列。
15.权利要求14所述的诊断组合物,其中所述的微阵列是cDNA微阵列。
16.权利要求14所述的诊断组合物,其中所述的微阵列是寡聚核苷酸微阵列。
17.一种癌症诊断试剂盒,包括用于检测选自Seq ID No.1-30、Seq IDNo.32、Seq ID No.34和Seq ID No.98的基因组合物表达的试剂。
18.权利要求17所述的试剂盒,进一步包括用于微阵列分析的试剂。
19.权利要求17所述的试剂盒,进一步包括一种媒介,通过这种媒介分析所说基因的核酸序列、它们的互补序列或者其部分。
20.权利要求19所述的试剂盒,其中所述的媒介是微阵列。
21.权利要求17所述的试剂盒,进一步包括操作指南。
22.一种癌症诊断试剂盒,包括用于检测选自Seq ID No.32-67、Seq IDNo.69和Seq ID No.98-100的基因表达的试剂。
23.权利要求22所述的试剂盒,进一步包括用于微阵列分析的试剂。
24.权利要求22所述的试剂盒,进一步包括一种媒介,通过这种媒介分析所说的基因的核酸序列、它们的互补序列或者其部分。
25.权利要求24所述的试剂盒,其中所述的媒介是微阵列。
26.权利要求25所述的试剂盒,进一步包括操作指南。
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US12018333B2 (en) | 2018-01-23 | 2024-06-25 | Excellen Medical | Method and kit for identifying lung cancer status |
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US6582908B2 (en) * | 1990-12-06 | 2003-06-24 | Affymetrix, Inc. | Oligonucleotides |
US6350576B1 (en) | 1994-12-20 | 2002-02-26 | Cold Spring Harbor Laboratory | Cancer detection probes |
US5695937A (en) * | 1995-09-12 | 1997-12-09 | The Johns Hopkins University School Of Medicine | Method for serial analysis of gene expression |
US6275814B1 (en) | 1996-11-27 | 2001-08-14 | Investment Strategies Network | Investment portfolio selection system and method |
US6003018A (en) | 1998-03-27 | 1999-12-14 | Michaud Partners Llp | Portfolio optimization by means of resampled efficient frontiers |
JP2004510951A (ja) | 1999-03-15 | 2004-04-08 | イオス バイオテクノロジー,インコーポレイティド | 結腸直腸癌を診断する新規の方法、組成物、結腸直腸癌調節のためのスクリーニング法 |
US6175824B1 (en) | 1999-07-14 | 2001-01-16 | Chi Research, Inc. | Method and apparatus for choosing a stock portfolio, based on patent indicators |
KR20020092891A (ko) | 1999-07-15 | 2002-12-12 | 리서치 디벨럽먼트 파운데이션 | 코르티코트로핀 분비 인자 수용체 2 결핍 마우스 및 이의용도 |
US6221600B1 (en) * | 1999-10-08 | 2001-04-24 | Board Of Regents, The University Of Texas System | Combinatorial oligonucleotide PCR: a method for rapid, global expression analysis |
US7105293B2 (en) * | 2000-09-19 | 2006-09-12 | Whitehead Institute For Biomedical Research | Genetic markers for tumors |
JP2005508135A (ja) * | 2001-03-09 | 2005-03-31 | ニューゲン テクノロジーズ, インコーポレイテッド | Rna配列の増幅のための方法および組成物 |
JP2005503779A (ja) * | 2001-06-10 | 2005-02-10 | アイアールエム,エルエルシー | 致死性の高い癌の分子シグネチャー |
US7348142B2 (en) * | 2002-03-29 | 2008-03-25 | Veridex, Lcc | Cancer diagnostic panel |
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- 2003-03-29 CN CN03131207A patent/CN100577813C/zh not_active Expired - Fee Related
- 2003-03-29 KR KR10-2003-0019811A patent/KR20030078799A/ko not_active Application Discontinuation
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AU2003203553A1 (en) | 2003-10-23 |
EP1355150A2 (en) | 2003-10-22 |
BR0303011A (pt) | 2004-02-17 |
CN100577813C (zh) | 2010-01-06 |
US20090221445A1 (en) | 2009-09-03 |
JP2009118855A (ja) | 2009-06-04 |
MXPA03002862A (es) | 2004-08-11 |
CN101705291A (zh) | 2010-05-12 |
US20030194733A1 (en) | 2003-10-16 |
CA2422319A1 (en) | 2003-09-29 |
JP4409845B2 (ja) | 2010-02-03 |
JP2004033215A (ja) | 2004-02-05 |
AR039210A1 (es) | 2005-02-09 |
EP1355150A3 (en) | 2004-08-25 |
US7348142B2 (en) | 2008-03-25 |
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