CN1422671A - Medical paste film - Google Patents
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- CN1422671A CN1422671A CN01140108A CN01140108A CN1422671A CN 1422671 A CN1422671 A CN 1422671A CN 01140108 A CN01140108 A CN 01140108A CN 01140108 A CN01140108 A CN 01140108A CN 1422671 A CN1422671 A CN 1422671A
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Abstract
The present invention relates to a medicinal base material for external application and transfermal absorption, and said base material is formed from polyvinyl alcohol, sodium carbox methyl cellulose and gelatine enzymolyzed, dialyzed and purified product, which is characterized by that after said product is applied on the skin or wound, a layer of air-permeable film closed to the skin can be formed, said layer of film can resist external dust and bacteria, and can provide medicine and nutrients for interior. The different medicine can be added into the base material, the medicine with different function can be obtained, can promote wound healing, and can be used for curing various dermatosis and other diseases.
Description
Patent of the present invention belongs to outer compress material and enepidermic category, is used for prevention and treatment wound infection and treats dermapostasis, dermatosis, muscle sprain and contusion, neuralgia and internal disease by Transdermal absorption.
When skin be scratched, scratch, scald, when burning, a light antibiotic medicine of smearing, heavy debridement, coating, the lid gauze rubberized fabric wanted, even take medicine and have an injection.Practical for convenience, some products with comprehensive function arise at the historic moment, and " adhesive bandage ", " Bandaid " or the like are exactly wherein representational product." SHANGSHI ZHITONG GAO " and " dog skin plaster " or the like also is the product of using always in addition.
This series products something in common must use exactly and mount backing material and binding material.Therefore it is not beautiful to produce outward appearance, and skin is tauted, and causes shortcomings such as skin allergy, increase cost easily.
The dermatologic major part exists with the form of " ointment " or " cream ", and these product common drawback are coated on the skin is exactly rubbed easily, and the medicated clothing of making dirty lessens the curative effect.If the covering gauze increases cost, be repugnant to the eye.
Suture for surgery all will cover the gauze rubberized fabric later on, perhaps wraps up with gauze.Could roll over gauze after two or three days and observe the operation stitching situation, if wound dehiscence or suppuration are late.Very inconvenient.
Patent of the present invention " medical ointment, film " refers to a kind of like this material, and with " cream " or " ointment ", or the form of " gel " did not exist when it used.After it is coated on skin or the wound, just change into thin film, thereby we are referred to as " cream film " to the material that this " cream " can transform " film ".The effect that makes the cream film have medical treatment and prevent when our deisgn product is so be referred to as " medical ointment, film ".
On the basis of hundreds of tests, this medical ointment, film has eight distinctive features: (1) microporous membrane has suitable mechanical strength and elongation at break and skin is had suitable caking property, thereby can be with skin flexible and can not chap and be not easy " peeling ".Change dressings or can slabbing tear or clean once taking off gently no the time with clear water, very convenient.(2) it produces one deck microporous membrane at skin or wound surface, and air permeability and good and poisture-penetrability are arranged.Life-time service does not have sultry sensation, can not cause skin allergy.(3) microporous membrane externally stop antibacterial and dust invasion (the narrowest part of antibacterial surpasses 1 micron, and the aperture of microporous membrane has only the 0.01-0.3 micron, thus antibacterial can't be from micropore the front enter), internally slow releasing pharmaceutical plays therapeutical effect.Because microporous membrane is close to skin, can be so overcome antibacterial from the shortcoming of invasion wound in side, slit around the gauze.Overcome the shortcoming that the conventional process wound must use gauze, adhesive plaster or mount backing material and binding agent.(4) microporous membrane is close to skin surface, can not rubbed.Overcome the shortcoming that most skin medication (cream, ointment) is rubbed easily, improved enepidermic utilization rate.The medicated clothing of can not making dirty.(5) coat this product later at the surgical incision suture, not only anti-inflammation and sterilization prevention infection but also can see the wound healing situation at any time was convenient to timely processing.(6) area, shape and the thickness of medical ointment, film coating can free adjustment, do not have " dead angle ".(7) most of cream film adopts colourless or light material, has overcome to use to mount the shortcoming that backing material or gauze adhesive plaster are repugnant to the eye.(8) this layer film has certain water resistance, meets water-soluble rising, and is close to again after the drying on the skin, can continue to play a role.Therefore coat after the cream film, even outlying " peeling ", water can " glue it " on skin again.
Can classify to medical ointment, film from different angles.(1) investigate from " cream " or " film ", can
Medical ointment, film is divided into " cream " property for advocating peace based on " film " property and between " cream " property and " film "
Three major types between the property.Can be close on the skin after being coated on skin or the wound based on the product of " cream " property,
Being difficult for full wafer tears.Based on the product of " film " property be coated in can be in blocks on the skin tear.Between both
Between the cream film then can be torn (2) resistance to water classification with the form of the sheet that looses from film: be divided into water-proof and
Not water-fast two big classes.Water-fast class cream film film forming is later on more water-fast, the left alone without help form that does not influence film on the film basically of staying of the globule.Not water-proof cream film film forming is met water-soluble expanding later on, and the moisture content volatilization recovers as before again later.
The difference of patent of the present invention and other patent mainly contains two: compare from macroscopic view (1), and adopting polyvinyl alcohol and sodium carboxymethyl cellulose in a lot of patents is filmogen, uses gelatin as viscosifier and excipient.Though patent of the present invention also adopts identical materials, the raw material that has is then different, thereby actual effect differs greatly.What patent for example of the present invention adopted is gelatin enzymolysis dialysis purification thing, rather than gelatin, so actual effect differs very big.So-called " gelatin enzymolysis dialysis purification thing ", refer to the gelatin is raw material, enzyme with special type is handled, and then dialysis is purified, product has kept micromolecular " general character " composition total in animal and human's body skin, remove " individual character " composition in the animal skin, thus this refined product reality be not " gelatin " itself, " allergy " and " rejection " in use can not take place react." gelatin enzymolysis dialysis purification thing (micromolecular collagen) " is as nutrient and promotes the material of wound healing to use in patent of the present invention.It and gelatin have only close elementary composition, but are not same substances, its physiological action difference.The main difference of this patent and other patent just is this.(2) from microcosmic relatively, we have prepared corresponding product according to other people patent, carry out microscopic observation, can find, gelatin is that form with the seabird structure is distributed in the continuous phase in their product.Because gelatin molecule is too big and localized rich is too high, is difficult to play the effect that nutrition is provided and promotes wound healing.And in our product, on hundreds of experimental basis, gelatin enzymolysis dialysis purification thing is evenly distributed in the continuous phase, overcome the excessive shortcoming of local concentration, it provides micromolecular collagen (people and zoodermic total composition) equably to skin (or wound), thereby has tangible nutrition and medical function.
Medical ointment, film mainly is made up of filmogen, solvent, auxiliary agent and medicine four parts.In order to simplify prescription, we adopt the principle of " one-object-many-purposes ", and the material that promptly has plays several effects simultaneously, for example water in this prescription be solvent be again pore-creating agent.Glycerol is nutrient substance, works the capillary effect of regulating again.
Patent formulation branch of the present invention " basic recipe " and " special formulation " two parts.Basic recipe is applicable to that large usage quantity and character differ bigger Chinese powder medicine or decocting for Chinese herbal medicine liquid and extract, adjusts consumption at prescription in the specified scope, and we can obtain one " cream is main " or based on the cream film of " film ".
" basic recipe " raw material weight is such as following:
Polyvinyl alcohol 2-12 part
Sodium carboxymethyl cellulose 2-12 part
Gelatin enzymolysis dialysis purification thing 0.5-6 part
Benzalkonium bromide (or benzene letter oronain) 0.05-1 part
Glycerol 1-15 part
100 parts in water
In fact, adopt following " special formulation " can both obtain a cream film based on " film " to the Chinese medicine (under the little condition of consumption) of most of Western medicine and purification, " special formulation " raw material weight is such as down:
6 parts of polyvinyl alcohol
3 parts of sodium carboxymethyl cellulose
1.5 parts of gelatin enzymolysis dialysis purification things
0.3 part of benzalkonium bromide (or benzene letter oronain)
8 parts of glycerol
100 parts in water
In " basic recipe " or " special formulation ", add special-purpose medicaments and just become the medical ointment, film of tool with given efficacy.
The medicine that uses in the medical ointment, film is divided into several classes of Western medicine and Chinese powder medicine and Chinese medicine extract.Below a few class medicines can be used as medicine and be added in the medical ointment, film: (1) anti-inflammation and sterilization medicine.(2) treat dermopathic medicine.(3) hemorrhage.(4) treatment muscular soreness, neuralgia, arthralgic medicine.(5) treat the medicine of spraining, dampening.The medicine of (6) treatment scald, burn.(7) can Transdermal absorption the medicine of treatment internal disease.(8) medicine of treatment genital organ disease (comprising sexually transmitted disease (STD)).(9) has the medicine of beautification function.(10) has the medicine that prevents and treat decubital ulcer.
Following material can be used as auxiliary agent and is added to the performance of removing to improve product in the medical ointment, film: white oil, various edible oil, sorbitol, xanthan gum, sodium alginate, chitosan, chitin, hyaluronic acid, sodium polyacrylate, polyacrylate and copolymer thereof etc.Polyethylene Glycol, polyvinylpyrrolidone, methylcellulose, hydroxypropyl cellulose, starch, modified starch, Kaolin, silicon dioxide, etc.
Embodiment:, (1) anti-inflammation and sterilization cream film: by 0.2 part of metronidazole of 100 parts of benzalkonium bromides of cream film of " special formulation " preparation, (add or do not add) 0.5 part, (2) No. two anti-inflammation and sterilization cream films: add at least following one or more medicine by 100 parts of the cream films of embodiment 1 preparation: chloramphenicol, (add or do not add) 0.4 part of erythromycin, (add or do not add) 0.4 part of radonil powder, (add or do not add) 0.5 part of gentamicin, (add or do not add) 0.5 part in addition; Can add the various anti-inflammation and sterilization medicines of approving in ( or not adding ) pharmacopeia in above-mentioned prescription, consumption and incompatibility are by the execution of stipulating on the pharmacopeia. ( 3 ) blood coagulation cream film: in addition by 15 parts of 100 parts of YUNNAN BAIYAO of cream film of " special formulation " preparation； Can add the various coagulants of approving in (or not adding) pharmacopeia in above-mentioned prescription; Consumption and incompatibility are by the execution of stipulating on the pharmacopeia., (4) skin ointment films, (diclofenac paste film): in addition by 1 part of 6 parts of azone of 100 portions of diclofenac diethylammonium salt of cream film, (add or do not add) of " special formulation " preparation; Can add the various dermatologics of approving in (or not adding) pharmacopeia in above-mentioned prescription; Consumption and incompatibility are by the execution of stipulating on the pharmacopeia., (5) No. two skin ointment films, (inspiring confidence in fine jade cream film): in addition by 1 part of 1 part of azone of 100 parts of bifonazoles of cream film, (add or do not add) of " special formulation " preparation; Can add the various dermatologics of approving in (or not adding) pharmacopeia in above-mentioned prescription, consumption and incompatibility are by the execution of stipulating on the pharmacopeia. (6) No. three skin ointment films (daktarin cream film):
100 parts of cream films by " special formulation " preparation
2 parts of miconazole nitrates
1 part of (7) No. four skin ointment film of azone (add or do not add) (encircling sharp cream film):
100 parts of cream films by " special formulation " preparation
1 part of ciclopirox olamine
1 part of (8) No. five skin ointment film of azone (add or do not add) (happy skin cream film)
100 parts of cream films by " special formulation " preparation
0.1 part of halcinonide
1 part of (9) angina pectoris cream of azone (add or do not add) film
100 parts of cream films by " special formulation " preparation
10 parts in nitroglycerine
1 part of azone (add or do not add)
In addition, in above-mentioned prescription, can add the transdermal of approving in (or not adding) pharmacopeia that has and absorb energy
The anginal medicine of the treatment of power, consumption and incompatibility are by the execution of stipulating on the pharmacopeia.(10) SHANGSHI ZHITONG GAO films:
100 parts of cream films by " special formulation " preparation
20 parts of methyl salicylate
2 parts of Borneolum Syntheticums
2 parts of Herba Menthaes
2 parts of Camphoras
1 part of azone (add or do not add)
5000 units of vitamin E (add or do not add)
1 part of vitamin B6 (add or do not add)
1 part of (11) No. two SHANGSHI ZHITONG GAO film of Semen daturae (add or do not add)
Press 100 parts of the cream films of embodiment 10 preparation
10 parts of Chinese medicine (Olibanum, Myrrha, Cortex Cinnamomi, Flos Caryophylli, Rhizoma Kaempferiae) ethanol leaching things
In addition, in above-mentioned prescription, can add the functions of relaxing muscles and tendons and promoting of approving in (or not adding) pharmacopeia that has
Various medicines or Chinese medicine, consumption and incompatibility are by the execution of stipulating on the pharmacopeia.(12) essential balm type cream film:
100 parts of cream films by " special formulation " preparation
6 parts of Mentholums
2 parts of Camphoras
2 parts of eucalyptus oils
1 part of eugenol
4 parts of Methyl Salicylates
1 part of white oil
1 part of (13) Flos Carthami oil type of azone (add or do not add) medical ointment, film:
100 parts of cream films by " special formulation " preparation
15 parts of safflower oils (commercial goods)
Azone (add or do not add) 1 part (14) has the medical ointment, film of beautification function:
100 parts of cream films by " special formulation " preparation
" SOD " 1 part
1 part of azone (add or do not add)
In addition, in above-mentioned prescription, can add following one or more help the material of improving looks, routine Radix Glycyrrhizae diammonium, sheep placental extract, Aloe extract, fruit acid, alginate, chitosan, chitosan derivatives, hyaluronic acid, or the like.(15) in " basic recipe " or " special formulation ", add one or more treatment sexually transmitted disease (STD)s
Medicine just becomes has controlled sexually transmitted disease (STD) cream film.These materials comprise povidon iodine, strong (or weak)
Argentoproteinum, podophyllum, or the like.Drug concentrations and incompatibility are carried out by the regulation in the pharmacopeia and are got final product.
We carry out application test on one's body oneself and volunteer and animal (chicken and exempt from), and are respond well, do not have skin allergy and rejection phenomenon.For example use an anti-inflammation and sterilization cream film on one's body inventor and relatives, in when scratch, or mosquito bite is when staving skin, or smears when on the skin pimple being arranged, and good result is all arranged.We can both heal as before about ten days exempting from son on one's body with operation 30 multitools (long 5 centimetres of the wherein maximum edge of a knife, blood pours out) that lancinated in half a year.Wherein four blade is to carry out on the meadow in the open in summer (2001.8.1-2001.8.24) in sweltering heat, and the mosquito fly is a lot of on every side, only is coated with a secondary cream film after the incised wound and heals about ten days.Mosquitos and flies does not bite wound.We burn till black and injure skin exempting from hair with lighter, electric cautery is burnt heat (reaching the temperature that makes melts soldering tin) scald test (time of contact in about 5 seconds) to exempting from son, blister do not occur at burn or scald position, restore as before about ten days.
Claims (12)
1. patent of the present invention belongs to external application and dermatologic category,, adds different medicines and just become the medical ointment, film with difference in functionality in mastic for primary raw material is mixed with mastic with polyvinyl alcohol, sodium carboxymethyl cellulose, gelatin enzymolysis dialysis purification thing etc.Be respectively applied for the anti-inflammation and sterilization of scuffing, scratch, knife injury, scald, burn, by Transdermal absorption treatment dermapostasis, dermatosis, is sprained and is ached neuralgia and internal disease muscle injury.It is characterized in that product is coated in meeting generation layer of transparent or translucent microporous membrane on skin or the wound, be close to skin surface, externally stop antibacterial and dust, internally slow releasing pharmaceutical and nutrient substance.Do not re-use gauze, adhesive plaster, mount backing material and binding material.Overcome and used above-mentioned material to be repugnant to the eye, can't to observe and in time handle the shortcoming of wound.Overcome the shortcoming that dermatologic (cream, ointment etc.) is rubbed easily.
2. according to claim 1, the raw material weight of " basic recipe " of patent of the present invention is such as following:
Polyvinyl alcohol 2-10 part
Sodium carboxymethyl cellulose 1-5 part
Gelatin enzymolysis dialysis purification thing 1-5 part
Glycerol 3-15 part
Benzalkonium bromide (add or do not add) 0.1-0.8 part
Water 80-120 part
This prescription is applicable to Chinese powder medicine or the Chinese medicine extract that adds with bigger, and in above-mentioned formula range, the character of cream film can artificial adjustment between " cream " and " film ".
3. according to claim 1 and 2, the raw material weight ratio of " special formulation " of patent of the present invention is:
6 parts of polyvinyl alcohol
3 parts of sodium carboxymethyl cellulose
1.5 parts of gelatin enzymolysis dialysis purification things
8 parts of glycerol
0.2 part of benzalkonium bromide (add or do not add)
100 parts in water
This prescription is applicable to and adds little Western medicine or the Chinese medicine purification thing of consumption.This moment, the cream film was to show " film ".
4. according to claim 2 and 3, in " basic recipe " or " special formulation ", add specified medicine and just become medical ointment, film with given efficacy.Below a few class medicines can be used as medicine and be added in the medical ointment, film: (1) anti-inflammation and sterilization medicine.(2) treat dermopathic medicine.(3) hemorrhage.(4) treatment muscular soreness, neuralgia, arthralgic medicine.(5) treat the medicine of spraining, dampening.The medicine of (6) treatment scald, burn.(7) can Transdermal absorption the medicine of treatment internal disease.(8) medicine of treatment genital organ disease (comprising sexually transmitted disease (STD)).(9) has the medicine of beautification function.(10) has the medicine that prevents and treat decubital ulcer.
Following material can be used as auxiliary agent and is added to the performance of removing to improve product in the medical ointment, film: white oil, various edible oil, sorbitol, xanthan gum, sodium alginate, chitosan, chitin, hyaluronic acid, sodium polyacrylate, polyacrylate and copolymer thereof etc.Polyethylene Glycol, polyvinylpyrrolidone, methylcellulose, hydroxypropyl cellulose, starch, modified starch, Kaolin, silicon dioxide, etc.
5. according to claim 2,3 and 4, the anti-inflammation and sterilization of be used to abrade, handling knife injury, burn, scald and suture for surgery rear surface and to have the cream pleurodiaphragmatic in terspace material weight ratio of acarid function extremely as follows:
100 parts of cream films according to claim 2 or 3 preparations
0.5 part of metronidazole
15 parts of Chinese powder medicine or extracts (add or do not add)
In addition, in above-mentioned prescription, can add the following anti-inflammation and sterilization material of one or more pharmacopeia approvals again: benzene letter oronain, ethacridine lactate (the rich slave's that of thunder), penicillins (amoxicillin, penicillin, cephalosporins (ceftazidime, rocephin, cefoperazone), aminoglycosides (streptomycin, tobramycin, gentamycin, neomycin, amikacin), Macrolide (Roxithromycin, Azithromycin), sulfonamides (sulfadiazine, sulfamethoxazole, compound sulfonamide, Trimethoprim), metronidazole, clindamycin, chloromycetin, enoxacin, ofloxacin, ciprofloxacin, SHUANGHUANLIAN, andrographolide etc.
Concentration and the incompatibility of above-mentioned medicine in patent of the present invention carried out by the regulation of corresponding medicine in the pharmacopeia.
6. according to claim 2,3 and 4, the raw material weight of blood coagulation cream film was such as following:
Press 100 parts of claim 2 or the 3 cream films of preparing
10 parts of Chinese powder medicine or extracts (add or do not add)
In addition, can add the hemorrhage of approving in one or more pharmacopeia again in above-mentioned prescription, concentration and incompatibility are carried out by the regulation of corresponding medicine in the pharmacopeia.
7. according to claim 2,3 and 4, in " basic recipe " or " special formulation ", can add approve in one or more pharmacopeia can treat dermopathic medicine, promptly become cream film with corresponding treatment function.Here the medicine of saying comprises ketoconazole, miconazole, clotrimazole, griseofulvin, cannitracin, sulfur, bifonazole, miconazole nitrate, ciclopirox olamine, halcinonide, diclofenac diethylammonium salt etc.Concentration and the incompatibility of these medicines in the cream film carried out by the regulation of corresponding medicine in the pharmacopeia.
Therefore, it is as follows to have a cream pleurodiaphragmatic in terspace material weight ratio of treatment various acute and chronic dermatosiss, contact dermatitis, neurodermatitis, lichen planus, psoriasis (psoriasis):
100 parts of the cream films that makes according to right 3 or 4
0.2 part of halcinonide
1 part of laurocapram (add or do not add)
0.5 part of azone (add or do not add)
10 parts of Chinese powder medicine or extracts (add or do not add)
Therefore, the raw material weight of " diclofenac paste film " is such as following:
Press 100 parts of claim 3 or the 4 cream films of preparing
6 parts of diclofenac diethylammonium salt
0.5 part of azone (add or do not add)
15 parts of Chinese powder medicine or extracts (add or do not add)
8. according to right 2,3 and 4, have anti-inflammation and sterilization, treatment seeking property acne and kill the cream pleurodiaphragmatic in terspace material weight ratio of acarid function as follows:
By claim 2,100 parts of the cream films of 3 preparations
0.5 part of metronidazole
0.3 part of ammonium glycyrrhizinate
0.5 part of azone (add or do not add)
10 parts of Chinese powder medicine or extracts (add or do not add)
In addition, in above-mentioned prescription, can add the medicine of approving in the pharmacopeia that can treat acne, decubital ulcer and just make corresponding cream film.
9. according to claim 2,3 and 4, a kind of raw material weight of SHANGSHI ZHITONG GAO film was such as following:
Press 100 parts of claim 2 or the 3 cream films of preparing
20 parts of methyl salicylate
2 parts of Borneolum Syntheticums
2 parts of Herba Menthaes
2 parts of Camphoras
1 part of eucalyptus oil (add or do not add)
1 part of Oleum Caryophylli (add or do not add)
1 part of azone (add or do not add)
5000 units of vitamin E (add or do not add)
1 part of vitamin B6 (add or do not add)
1 part of Semen daturae (add or do not add)
10 parts of Chinese powder medicine or extracts (add or do not add)
10. according to claim 2,3 and 4, the weight ratio with the cream pleurodiaphragmatic in terspace material for the treatment of the angina pectoris effect is as follows:
Press 100 parts of claim 2 or the 3 cream films of preparing
15 parts in nitroglycerine (stabilizing treatment)
05 part of azone (add or do not add)
15 parts of Chinese powder medicine or extracts (add or do not add)
11., in " basic recipe " or " special formulation ", add one or more materials and just become the beauty cream film with beautification function according to claim 2,3 and 4.These materials comprise " SOD ", the Radix Glycyrrhizae diammonium, and sheep placental extract, Aloe extract, chitosan, chitosan derivatives, fruit acid, alginate, hyaluronic acid, or the like.Drug concentrations and incompatibility are carried out by regulation in the beauty treatment and are got final product.
12. according to claim 2,3 and 4, the medicine that adds one or more treatment sexually transmitted disease (STD)s in " basic recipe " or " special formulation " just becomes has controlled sexually transmitted disease (STD) cream film.These materials comprise povidon iodine, strong (or weak) argentoproteinum, and podophyllum, or the like.Drug concentrations and incompatibility are carried out by the regulation in the pharmacopeia and are got final product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN01140108A CN1422671A (en) | 2001-11-23 | 2001-11-23 | Medical paste film |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN01140108A CN1422671A (en) | 2001-11-23 | 2001-11-23 | Medical paste film |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1422671A true CN1422671A (en) | 2003-06-11 |
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Family Applications (1)
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|---|---|---|---|
| CN01140108A Pending CN1422671A (en) | 2001-11-23 | 2001-11-23 | Medical paste film |
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Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103239391A (en) * | 2013-05-16 | 2013-08-14 | 江苏圣宝罗药业有限公司 | Tacrolimus ointment |
| CN105288697A (en) * | 2015-11-13 | 2016-02-03 | 邢月军 | Medical film for surgery |
| CN105311684A (en) * | 2015-11-13 | 2016-02-10 | 邢月军 | Surgical film for stopping bleeding and relieving pain |
| CN105327384A (en) * | 2015-11-19 | 2016-02-17 | 耿文真 | Absorbable medical biological membrane dressing and preparation method thereof |
| CN105363065A (en) * | 2015-11-13 | 2016-03-02 | 邢月军 | Antibacterial and anti-inflammatory membrane |
| CN105381499A (en) * | 2015-11-19 | 2016-03-09 | 耿文真 | Medical membrane with effect of promoting wound healing and preparation process thereof |
| CN105396171A (en) * | 2015-11-19 | 2016-03-16 | 耿文真 | Medical film with antisepsis and anti-inflammation effects and preparation process thereof |
| CN105497976A (en) * | 2016-01-07 | 2016-04-20 | 青岛大学 | Preparation method of externally applied functional ointment for traumatic wounds |
| CN105561381A (en) * | 2016-01-07 | 2016-05-11 | 青岛大学 | Preparation method of marine organism nano antibacterial gel-liquid adhesive bandage |
| CN105963758A (en) * | 2016-06-06 | 2016-09-28 | 湖州国信物资有限公司 | Medical membrane with anti-inflammation and antibacterial effects |
| CN106178068A (en) * | 2016-08-18 | 2016-12-07 | 广州华弘生物科技有限公司 | A kind of pad pasting promoting wound healing and stiching instrument |
| CN107028874A (en) * | 2017-06-07 | 2017-08-11 | 首都医科大学附属北京朝阳医院 | External-applied ointment |
| CN108339149A (en) * | 2018-04-27 | 2018-07-31 | 泰州市榕兴医疗用品股份有限公司 | A kind of preparation method of the aerogel dressing containing vitamin e |
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2001
- 2001-11-23 CN CN01140108A patent/CN1422671A/en active Pending
Cited By (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103239391B (en) * | 2013-05-16 | 2015-03-18 | 江苏知原药业有限公司 | Tacrolimus ointment |
| CN103239391A (en) * | 2013-05-16 | 2013-08-14 | 江苏圣宝罗药业有限公司 | Tacrolimus ointment |
| CN105363065A (en) * | 2015-11-13 | 2016-03-02 | 邢月军 | Antibacterial and anti-inflammatory membrane |
| CN105288697A (en) * | 2015-11-13 | 2016-02-03 | 邢月军 | Medical film for surgery |
| CN105311684A (en) * | 2015-11-13 | 2016-02-10 | 邢月军 | Surgical film for stopping bleeding and relieving pain |
| CN105381499A (en) * | 2015-11-19 | 2016-03-09 | 耿文真 | Medical membrane with effect of promoting wound healing and preparation process thereof |
| CN105327384A (en) * | 2015-11-19 | 2016-02-17 | 耿文真 | Absorbable medical biological membrane dressing and preparation method thereof |
| CN105396171A (en) * | 2015-11-19 | 2016-03-16 | 耿文真 | Medical film with antisepsis and anti-inflammation effects and preparation process thereof |
| CN105497976A (en) * | 2016-01-07 | 2016-04-20 | 青岛大学 | Preparation method of externally applied functional ointment for traumatic wounds |
| CN105561381A (en) * | 2016-01-07 | 2016-05-11 | 青岛大学 | Preparation method of marine organism nano antibacterial gel-liquid adhesive bandage |
| CN105497976B (en) * | 2016-01-07 | 2018-07-10 | 青岛大学 | A kind of trauma wound is applied with the preparation method with functional ointment |
| CN105963758A (en) * | 2016-06-06 | 2016-09-28 | 湖州国信物资有限公司 | Medical membrane with anti-inflammation and antibacterial effects |
| CN106178068A (en) * | 2016-08-18 | 2016-12-07 | 广州华弘生物科技有限公司 | A kind of pad pasting promoting wound healing and stiching instrument |
| CN107028874A (en) * | 2017-06-07 | 2017-08-11 | 首都医科大学附属北京朝阳医院 | External-applied ointment |
| CN108339149A (en) * | 2018-04-27 | 2018-07-31 | 泰州市榕兴医疗用品股份有限公司 | A kind of preparation method of the aerogel dressing containing vitamin e |
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