CN1296084C - Externally applied medicine for treating chronic dermatopathy - Google Patents
Externally applied medicine for treating chronic dermatopathy Download PDFInfo
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- CN1296084C CN1296084C CNB2004100738888A CN200410073888A CN1296084C CN 1296084 C CN1296084 C CN 1296084C CN B2004100738888 A CNB2004100738888 A CN B2004100738888A CN 200410073888 A CN200410073888 A CN 200410073888A CN 1296084 C CN1296084 C CN 1296084C
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Abstract
The present invention relates to an external application medicine for treating obdurate skin diseases which have high morbidity, such as psoriasis, neurodermatitis (stubborn lichen), tinea of feet and hands (goose-foot wind), body tinea, versicolor tinea, eczema, ribbon rashes, etc. The present invention is characterized in that the present invention comprises raw material ingredients and weight percent thereof as follows: 0.5% to 15% of kosam seed, 2.0% to 30.0% of aloe, 0.05% to 1.0% of musk, 1.0% to 15.0% of propolis, 70% of alcohol and 10.0% to 50.0% of redistilled water. The external application medicine has the advantages of convenient application of medicines, quick medicinal effect and no recurrence, and the cure rate is 100%.
Description
Technical field
The present invention relates to be used for the treatment of the medicine for external use of refractory skin, sickness rate such as specifically a kind of treatment psoriasis (psoriasis), neurodermatitis (stubborn dermatitis), tinea manus and pedis (fungal infection of hand and foot), tinea corporis, tinea versicolor, chronic eczema, herpes zoster are higher, the dermopathic medicine for external use of obstinate refractory.Belong to the dermopathic medicine for external use of the treatment of innovating field of medicaments.
Background technology
Utilization Chinese medical theory and Chinese medicinal formulae, adopts dialectical execute control, the method for internal-external therapy treated some common chronic and refractory dermatosiss and had history in several thousand.In recent years, inheriting and developing on the basis of Chinese medicine advantage, in conjunction with and adopt advanced Medical Technology and Protocols in Molecular Biology, open one's minds, innovate prescription, carry out dermopathic research treatment obtained many great achievements.Yet, at chronic dermatosis such as the psoriasis (psoriasis) of obstinate refractory, neurodermatitis (stubborn dermatitis), tinea manus and pedis (fungal infection of hand and foot), tinea versicolor, tinea corporis, chronic eczema, herpes zoster etc., up at present, at home and abroad field of medicaments still lack advanced, novel, efficiently, the Therapeutic Method and the medicine that can effect a radical cure.
The present invention is on the basis of secret prescription handed down in the family from generation to generation, adopt advanced high-tech means, several Chinese medicines and emerging kind medicine are carried out the retrofit and the process of preparing Chinese medicine, traditional monarch, minister, assistant, make it to carry out on the tcm theory compatibility, be equipped with biopolymer medicine again and permeate through all the impaired epidermises of affected skin comprehensively with efficient infiltration function, hypodermal cell, kill all pathogenic microorganism and virulence factor, thereby greatly given play to eliminating pathogenic factor for supporting vital QI, radical cure dermatosis and recovery normal skin form and physiological function are eradicated the chronic dermatosis of these obstinate refractory.
Summary of the invention
The object of the present invention is to provide a kind of have curative effect fast, nontoxic, have no side effect, and can effect a radical cure the serial medicine for external use of refractory skins such as psoriasis (psoriasis), neurodermatitis (stubborn dermatitis), tinea manus and pedis (fungal infection of hand and foot), tinea corporis, tinea versicolor, chronic eczema, herpes zoster.
For achieving the above object, under the Chinese medicine basic theories instructs, attribute and combination principle according to medicine, to some Chinese medicines and emerging kind medicine carries out a large amount of screenings and medicine is tested compatibility, adopted the technical scheme of innovating, utilization modern science and technology method is after the selected meticulous refinement of medicine process and making with extra care, carry out organic assembling, made best exterior-applied prescription.
One of feature of the present invention is composition of raw materials novelty, advanced person, uniqueness, has embodied the research and development direction of Chinese medicine applied research " blending the east and the west " in line with international standards, makes Chinese medicine and emerging kind medicine and Western medicine organic assembling, gives full play to pharmacological action.
Composition of raw materials: (main pharmaceutical compositions by weight percentage)
(1) Fructus Bruceae 0.5%～15%
(2) Aloe 2.0%～30.0%
(3) Moschus 0.05%～1.0%
(4) propolis 1.0%～15.0%
(5) sulfur 3.0%～20.0%
(6) chitosan 2.0%～10.0%
(7) salicylic acid 4.0%～15.0%
(8) sodium chloride 1.0%～20.0%
(9) 70% ethanol 15.0%～25.0%
(10) distilled water 10.0%～50.0%.
Pharmacology and function
According to the record of medical book and document, the property of medicine of each component in the innovation prescription, pharmacology is respectively:
(1) Fructus Bruceae (another name Semen Sophorae Flavescentis, Ovum Anas domestica) bitter cold.Function with damp eliminating, parasite killing.The modern biology technology proves that it contains Brusatol, and compositions such as brucein have antibiotic, antiinflammation; Its contained alkaloid and Saponin have solubilising protein and dispel the effectiveness of pathological changes damaged tissues cell.
(2) Aloe: bitter cold.Function with parasite killing, relieving constipation, heat clearing away, cool liver.Known active ingredient aloin, aloe-emodin etc., resins etc. have antibiotic, especially kill the effect of der Pilz.
(3) Moschus: Xin Wen.Have one's ideas straightened out the meridian dredging, invigorate blood circulation, reducing swelling and alleviating pain.Modern biotechnology studies have shown that it contains muscone, Moschus is given a tongue-lashing pyridine, multiple proteins and aminoacid and trace element, remove and have excitor nerve system and cardiovascular function, outside the antibacterial action, also has the effect that strengthens epinephrine and β one receptor, and β one catecholamine there is booster action, helps to recover the form and the physiological function of normal skin tissue.
(4) propolis: gather and sneaked into the colloid substance that glandular secretion thing and Cera Flava etc. process as Apis, contain multiple effective active components, its medical value is on the books very early, but real scientific research is that the composition of isolation identification has flavonoid, terpenes, quinones, esters, ketone, fatty acid, aminoacid, aromatic acid, vitamin, polysaccharide, mineral from propolis over nearly 30 years.Propolis has and purifies the blood, safeguards cardiovascular system, regulates immunity, adjusts functions such as endocrine, and has and can activate histiocyte, promotes the effect of cell regeneration.
(5) sulfur: acid temperature, poisonous.Has the tonifying YANG cold expelling, relieving constipation, parasiticidal effect, external curing tinea, skin ulcer, leprosy.Modern study shows that its external curing dermatosis has multiple pharmacodynamic feature.
(6) chitosan:, have excellent antibiotic, antiinflammatory, wound healing, functions such as low-molecular-weight transdermal as the chitosan of emerging kind medicine of modern times.Simultaneously, be again good pharmaceutical carrier, adjuvant and slow releasing agent.
(7) salicylic acid: as typical chemicals one Western medicine, it is colourless crystallization or white crystals, slightly the powder of sweet taste.Have and suppress antibacterial and kill fungus and effect such as antipruritic.
(8) sodium chloride: colourless cube crystallization or white crystalline powder, salty in the mouth.Being the main electrolyte in the extracellular fluid, is the weight composition of keeping osmotic pressure and capacity, also has the effect of cleaning-sterilizing.
(9) ethanol: colourless clear liquid, bright strong, the easy firing of flavor.As solvent and disinfectant 60%-90% solution antibacterial and most of microbe all there are killing action, the strongest with 70% alcoholic solution sterilizing power.Simultaneously, it is strong that its 60%-70% alcoholic solution has a penetration, can distend the blood vessels, and blood circulation is accelerated, and promotes cell metabolism, activates the regeneration function of cambium cell then.
Two of feature of the present invention be the medicine of selected Chinese medicine and emerging kind medicine to different with compatibility dosage, the prescription of producing is also different, can form the various dermopathic topical agents of treatment of series.
Three of feature of the present invention be the utilization modern means of science and technology concoct, refine and processing and dosage form composite, thereby formulated feasible scheme for adopting modern high technology and sophisticated equipment to carry out modernization, standardization, large-scale production.
Four of feature of the present invention be from select materials, processing and fabricating operates by standardized program to preparation is all strict, that whole process all realizes is pollution-free, nontoxic, have no side effect, not only the medicine health is up to standard, and is safe and reliable, and determined the direction of the sustainable development of environmental protection.
That medicine for external use of the present invention has is significantly antipruritic, effect and efficient the transdermal function and the soluble protein of sterilization, pathogenic microbe killing, dispel the impaired histiocytic effect of pathological changes, also has the histiocytic function of quick reparation damaged skin simultaneously.Thereby reach the dermopathic purpose of the various stubbornnesses of radical cure.
Therefore, medicine for external use of the present invention is used for the treatment of refractory skins such as psoriasis (psoriasis), neurodermatitis (stubborn dermatitis), tinea manus and pedis (fungal infection of hand and foot), tinea corporis, tinea versicolor, eczema, herpes zoster and has the effect that drug effect is rapid, cure rate is high, do not recur.
The using method of medicine for external use of the present invention is simple, does not hinder the skin of normal health, and is nontoxic, have no side effect.As long as strictness does not get wet by medical routine disinfection method and protection coating place, can take effect soon.
Concrete coating method: illing skin washes with water, behind the normal saline flushing, use the ethanol routine disinfection, this medicine is applied to very thin one deck in affected part (be coated with according to course of disease length and lesion degree 0.2 to 1.0mm thick), observed the illing skin response situation 2 to 15 minute time, change situation according to state of an illness weight and pathological changes, go again and clean, fix and get final product with the deposited lid of thin layer sterile gauze, binder then with normal saline.
Medicine for external use of the present invention is evident in efficacy:
1, can cure for two to three times with dermatosis coatings such as interior psoriasis (psoriasis) and various stubborn dermatitis, tinea corporis, tinea manus and pedis for 1 year, never recurrence.Pathological changes more than 1 year, coating also can be cured for several times.
2, for eczema, herpes zoster, the general coating that only needs once can be cured never recurrence.
The specific embodiment:
Embodiment 1: the prescription of treatment psoriasis (psoriasis):
Fructus Bruceae 50 gram, Aloe 60 grams, Moschus 5 grams, 50 yuan of propolis, sulfur 90 grams, chitosan 60 grams, salicylic acid 60 grams, sodium chloride 25 grams, 70% ethanol, 200 grams, the above medicine of distilled water 400 grams through being carefully dished up and composite after, make liniment.Patient's effect is excellent.
Model case: the king * *, the man, 75 years old, people from Funing County, Hebei province, two femoribus internus were suffered from psoriasis 50 years, once in Beijing, ground various big hospitals such as Shanghai, Harbin carried out treatment, cured back recurrence again in 1-2 month, and were serious gradually.Be coated with applying treatment in May, 1996 via this medicament and promptly cure not recurrence so far for 15 times fully.
Liu * *, the man, 40 years old, people from Qinhuangdao suffered from psoriasis more than 2 years, was coated with applying treatment 2 promptly complete healing, no longer recurrences so far in July, 1996 through this medicament.
Embodiment 2: the prescription of treatment neurodermatitis (stubborn dermatitis):
Fructus Bruceae 25 grams, Aloe 95 grams, Moschus 5 grams, propolis 70 grams, sulfur 100 grams, chitosan 60 grams, salicylic acid 40 grams, sodium chloride 55 grams, 70% ethanol, 400 grams, distilled water 400 grams.
Above medicine through being carefully dished up and composite after, make liniment.It is convenient to use, and hears to imitate mystery.
Model case: Lee * *, the man, 62 years old, Qinhuangdao Shanhaiguan District people, two upper limb, two lower limb extensively suffer from neurodermatitis (stubborn dermatitis) more than 20 year, through multi-treatment, all do not have remarkable result, and the plump all the more sulci of skin of skin is deepened, and is tongue Portugal sample and becomes also scratchy difficult the dormancy.Recovery from illness behind in June, 1997 coated medicament 12 times, it is normal that skin recovers, so far recurrence.
Embodiment 3: treat in the prescription of tinea pedis, tinea corporis, tinea versicolor:
Fructus Bruceae 50 grams, reed meeting 75 grams, Moschus 5 grams, propolis 25 grams, sulfur 100 grams, chitosan 50 restrains, salicylic acid 90 grams, sodium chloride 35 grams, 70% ethanol, 270 grams, distilled water 300 grams.
Above each component medicine through being carefully dished up and composite after make liniment.Be applied to the treatment of various tinea manus and pedis (fungal infection of hand and foot), tinea corporis, tinea versicolor, effect is highly significant all.
Model case: the Yin Dynasty * *, man 35 years old, people from Shanhai Pass, Qinhuangdao suffered from tinea manus and pedis (fungal infection of hand and foot) more than 7 years, take a turn for the better through curing in many ways not have, in April, 1997 through be coated with put this medicine 10 times on the skin after recovery from illness recurrence so far.
Together * *, the woman, 53 years old, the Pekinese, both hands are dry broken strong, peel, itch, especially increased the weight of winter 15 years, through many large hospital treatments, do not have significantly and take a turn for the better.In in August, 1997 through be coated with put this medicine 6 times on the skin after the former sick skin that decreases recover normal, do not have recurrence so far.
Liu * *, the man, 56 years old, the Pekinese suffered from tinea corporis, tinea cruris 12 years, the light summer in winter is heavy, obstinate, in June, 1998 through be coated with put this medicine 12 times on the skin after recovery from illness, it is normal that skin recovers.
The king * *, the woman, 42 years old, people from Xuzhou, because of the multiple soybean grain size in positions such as breast, the back of the body, neck, shoulder and upper limb, filbert, squama class rash 15 years is sought medical advice in many ways, poor effect, summer is serious.In in August, 1997 recovery from illness after being coated with this medicine 20 times, recurrence so far, it is normal that skin recovers.
Embodiment 4: the prescription of treatment chronic eczema:
Fructus Bruceae 25 grams, Aloe 100 grams, Moschus 5 grams, propolis 50 grams, sulfur 60 grams, chitosan 60 grams, salicylic acid 30 grams, sodium chloride 50 grams, 70% ethanol, 220 grams, distilled water 400 grams.
Above each component medicine through being carefully dished up and composite after add an amount of medical ball scholar material again and make ointment, be applied to the chronic eczema treatment, effect is excellent.
Model case: Cui * *, the woman, 25 years old, the Pekinese, because of fat since the childhood, multiple eczema, again and again more than 20 year, in July, 1997, recovery from illness, recurrence so far after being coated with this medicine 15 times.
Embodiment 5: the prescription of treatment herpes zoster:
Fructus Bruceae 50 grams, Aloe 75 grams, Moschus 10 grams, propolis 60 grams, sulfur 50 grams, chitosan 100 grams, salicylic acid 25 grams, sodium chloride 30 grams, 70% ethanol, 300 grams, distilled water 300 grams.
More than each medicine through being carefully dished up and composite after make liniment, treatment herpes zoster, curative effect mystery.
Model case: the king * *, the woman, 37 years old, people from Funing County trike " heavy cold " and reaches " herpes zoter around waist " lower back two draining blebs at the beginning of 1997 4 months, pain unbearably, through hospitalize, effect is not remarkable.Put this medicine on the skin only after half an hour after be coated with, not only relieve the pain immediately, antipruritic, and vesicle disappears, the recovery from illness of bringing down a fever does not immediately stay any cicatrix of skin.
Claims (1)
1, a kind of medicine for external use that is used for the treatment of refractory skin, its feature is made up of by its percentage by weight following component:
(1) Fructus Bruceae 0.5%～15%
(2) Aloe 2.0%～30.0%
(3) Moschus 0.05%～1.0%
(4) propolis 1.0%～15.0%
(5) sulfur 3.0%～20.0%
(6) chitosan 2.0%～10.0%
(7) salicylic acid 4.0%～15.0%
(8) sodium chloride 1.0%～20.0%
(9) 70% ethanol 15.0%～25.0%
(10) distilled water 10.0%～50.0%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2004100738888A CN1296084C (en) | 2004-09-08 | 2004-09-08 | Externally applied medicine for treating chronic dermatopathy |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2004100738888A CN1296084C (en) | 2004-09-08 | 2004-09-08 | Externally applied medicine for treating chronic dermatopathy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1605358A CN1605358A (en) | 2005-04-13 |
| CN1296084C true CN1296084C (en) | 2007-01-24 |
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| Application Number | Title | Priority Date | Filing Date |
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| CNB2004100738888A Expired - Fee Related CN1296084C (en) | 2004-09-08 | 2004-09-08 | Externally applied medicine for treating chronic dermatopathy |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11278583B2 (en) * | 2018-03-29 | 2022-03-22 | Zhuanshe DU | Traditional Chinese medicine composition for treating diseases caused by human papillomavirus, preparation method and use thereof |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101185674B (en) * | 2007-12-11 | 2010-11-10 | 童小桃 | Infusion medicine for treating tinea pedis |
| CN106692403A (en) * | 2015-11-13 | 2017-05-24 | 谭惠娟 | Antipruritic ointment and preparation method thereof |
| CN111184714A (en) * | 2020-02-17 | 2020-05-22 | 重庆大学 | Application of brucea javanica picrol in preparation of medicines for preventing or treating inflammatory diseases |
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2004
- 2004-09-08 CN CNB2004100738888A patent/CN1296084C/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11278583B2 (en) * | 2018-03-29 | 2022-03-22 | Zhuanshe DU | Traditional Chinese medicine composition for treating diseases caused by human papillomavirus, preparation method and use thereof |
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| Publication number | Publication date |
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| CN1605358A (en) | 2005-04-13 |
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