CN1413604A - Method for preparing medicine for treatment of arthralgia-syndrome pain disease - Google Patents
Method for preparing medicine for treatment of arthralgia-syndrome pain disease Download PDFInfo
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- CN1413604A CN1413604A CN 01136639 CN01136639A CN1413604A CN 1413604 A CN1413604 A CN 1413604A CN 01136639 CN01136639 CN 01136639 CN 01136639 A CN01136639 A CN 01136639A CN 1413604 A CN1413604 A CN 1413604A
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Abstract
A Chinese medicine in the form of medicinal bag, ointment, or liniment for treating rheumatoid arthritis, hyperosteogeny, cervical spondylopathy, coronary heart disease, chronic hepatitis, asthma, etc is prepared from more than 10 Chinese-medicinal materials including ephedra, cinammon twigs, Sichuan aconite root, Chinese angelica root, etc. Its advantages are high cure rate and low recurrence rate.
Description
The invention belongs to the external used medicine that the pure Chinese medicine of a kind of usefulness is made, and relate to its prescription composition and manufacture method.
At present, though it is good with oral drugs and muscle, intravascular injection medical treatment disease effects, but still exist many weak points, for example: infect infectious disease because of muscle redness, bacterial infection, intravascular injection due to the injectable drug, and the drug side effectes such as drug induced gastritis that oral drugs cause happen occasionally, in addition, the phenomenon that careless needle body fractures when intramuscular injection is also of common occurrence.For overcoming the deficiency of said method, many medical workers adopt the method for inner disease outer treat, have obtained certain effect, but many external used medicines, because the active ingredient deficiency of medicine, and manufacture method is not good, make the drug penetration difference and do not have the effect of disease preventing and treating.
The objective of the invention is to overcome above-mentioned the deficiencies in the prior art, and provide a kind of with the Chinese medicine natural material, with not the containing hormone, have no side effect of unique technology preparation, safe in utilization, the short treating period of curing the disease, instant effect, to rheumatoid arthritis, hyperosteogeny, lumbago and skelalgia chronic diseases cure rate height, external used medicine that relapse rate is low.
For realizing above-mentioned purpose, the present invention adopts to have pharmacological research and the effective natural Chinese medicinal herb of clinical verification to make each component Chinese herbal medicine content of its prescription composition: (unit: gram) Herba Ephedrae 1 Ramulus Cinnamomi 1 Radix Aconiti Preparata 2 Radix Aconiti Kusnezoffii Preparatas 2 Radix Angelicae Sinensis 2 Rhizoma Arisaematis 0.8 Semen Persicae 1 Stigma Croci 1.2 Cortex Phellodendris 1 Radix Et Rhizoma Rhei 2 Radix Angelicae Pubescentiss 1.2 breasts do not have each 1 Borneolum Syntheticum, 0.03 Camphora 0.02
In actual production, can by the content ratio expansion deal of above-mentioned each medical herbs of prescription, make different classes of medicine external preparation such as externally used medicine bag, plaster, liniment according to the size of volume of production through certain processes.
The present invention is further illustrated with regard to specific embodiment below.The embodiment of the invention one: earlier with Herba Ephedrae, Ramulus Cinnamomi, Radix Aconiti, Radix Aconiti Kusnezoffii, Radix Angelicae Sinensis, Semen Persicae, Flos Carthami, Cortex Phellodendri, Radix Et Rhizoma Rhei, medical materials such as Radix Angelicae Pubescentis are put and are dried in the sun, and remove impurity contained in the medicine and mould matter product.The requirement of processing by medicine physics and chemistry big gun cleans big gun and processs oven dry.Every kind of medicine after the oven dry enlarges content ratio in the prescription composition according to the number of volume of production, with pulverizer medicine is pulverized to mix and stirs the back and cross 80～100 mesh sieve patent medicine powder.In addition, again Camphora, Borneolum Syntheticum are enlarged each components contents ratio in its prescription in volume of production, cross 80～100 mesh sieves with the metal trough grind up and become powder, at last Borneolum Syntheticum, camphor powder are mixed mutually with other Chinese medicine powder and mix thoroughly, weigh up medicated powder 15～30g, or weigh up medicated powder by actual requirement, and pack into and a kind ofly make in the deck made from cotton and other material, then deck is reinstalled a kind of strip sheath band the inside made from cloth.During use the sheath band is fixed on body surface position or acupuncture point, reaches the purpose of disease preventing and treating by the osmosis of about thing.
Medicinal bag and medicine expand the profile of cover band, or size and color, can establish juice according to actual needs and make.The making material of medicated bag and sheath band is that textile fabric or the fabric that does not have Chemical fiber component all can.
The embodiment of the invention two, processing and fabricating externally applied ointment of the present invention, the method for processing plaster is divided into two kinds.First method is: take by weighing Oleum sesami and put into pot, heating is endured out, with Herba Ephedrae, Ramulus Cinnamomi, Radix Aconiti Preparata, Radix Aconiti Kusnezoffii Preparata, Radix Angelicae Sinensis, Rhizoma Arisaematis, Semen Persicae, Flos Carthami, Cortex Phellodendri, Radix Et Rhizoma Rhei, Radix Angelicae Pubescentis is mixed thoroughly after assorting by the content exaggerated scale of every herbal medicine in the above-mentioned prescription composition according to processing capacity, drop in the oil cauldron (Oleum sesami want height take the dish out of the pot inside medicine face 3～5cm, medicine all is immersed in the oil), continue heating and tempered 2 hours, make the temperature in the oil cauldron be controlled at 280～300 ℃, refine to fluid and splash into Cheng Zhu in the water, that blows does not loose, can stop heating, when temperature is reduced to 260 ℃, plaster raw material Plumbum preparatium (in right amount) the limit edged of crossing 80～100 mesh sieves be stirred, spray into a little cold water and remove cigarette until adding, when treating that temperature is reduced to 70 ℃, the Borneolum Syntheticum of 100 mesh sieves will be pulverized, Camphora, breast does not have powder (ratio according to each medicine in the prescription composition is assorted by volume of production) to add, and stirs, add the cold water submergence again, soak 24～48h, releasing fire-toxin takes out then, thermoplastic, the stand is applied to mount and promptly gets externally applied ointment of the present invention on the backing material.With the thermoplastic of plaster tepor, be affixed on acupuncture point and affected part during use.Reach the purpose of preventing and curing diseases by the drug osmotic effect.Plaster mount the available kraft paper of backing material, cloth and permeability material preferably.The big I of the face shaping of plaster designs and produces according to actual needs.
The 2nd kind of processing plaster method of embodiment two is:
First with Herba Ephedrae, Ramulus Cinnamomi, Radix Aconiti Preparata, Radix Aconiti Kusnezoffii Preparata, Radix Angelicae Sinensis, Semen Persicae, Flos Carthami, Cortex Phellodendri, Radix Et Rhizoma Rhei, Radix Angelicae Pubescentis, Rhizoma Arisaematis are by the processing of medical material requirement, and screening is dried, according to various content of medicines ratios in the above-mentioned prescription composition, after enlarging deal and take by weighing respectively by the number of producing, mix is ground into fine powder together, and is moistening with 90% ethanol, put into percolator, the shop is even to flatten, and top raggle block gauze is put into 90% ethanol liquid then and exceeded medicinal powder face 15～20cm, soak 24h, the beginning percolation, flow velocity is 150ml/mim, collects percolate.Percolate reclaims ethanol, and it is standby to be concentrated into the thick paste shape.By the content ratio in the above-mentioned prescription composition, after the deal that enlarges medicine according to production quantity takes by weighing, pulverize mix homogeneously and cross 100 mesh sieves standby the Olibanum Myrrha.In addition Camphora, Borneolum Syntheticum are enlarged deal by volume of production and take by weighing, use 95% dissolve with ethanol, standby.Take by weighing plaster raw material raw rubber (by the amount of total dose 50%) and be cut into strip, clean oven dry, be pressed into the thick thin slice of 2～3mm then, place 24 hours standby.Take by weighing Colophonium (by the amount of total dose 50%), gasoline (by the amount of total dose 70%), then the sheet rubber and the Colophonium that press are put into agitator, add whole gasoline, stir 30mim and leave standstill 24h, restir 2h, add wintergreen oil 20 grams, lanoline 100 grams, vaseline 50 grams, zinc oxide (by the amount of total dose 70%), breast do not have the alcoholic solution of powder, Camphora and Borneolum Syntheticum, and, continue to stir more than 6 hours, with 80 mesh sieve filter pressings with the spissated Chinese medicine thick paste of ethanol percolation, filtrate is left standstill a week, can spread out to be coated with.
The stand is when being coated with, and with the pastille rubber cement, the stand is applied on the glue spreader, and by the Drying tunnel drying, dry by the fire in the tunnel 80～90 ℃ of temperature, the Drying tunnel rear part temperature can hang down, and then, the medicine adhesive plaster that coats is rolled up be cut into 5 * 7cm
2Or suitably big or small specification, conform to the plastics pharmaceutical film again and promptly get externally applied ointment of the present invention.During use, tear softening affected part and the acupuncture point of being affixed on of plastic foil on the plaster or tepor off, the osmosis by medicine reaches the disease preventing and treating purpose.
The embodiment of the invention three: the method for processing and fabricating liniment of the present invention is first with Herba Ephedrae, Ramulus Cinnamomi, Radix Aconiti Preparata, Radix Aconiti Kusnezoffii Preparata, Radix Angelicae Sinensis, Semen Persicae, Flos Carthami, Cortex Phellodendri, Radix Et Rhizoma Rhei, Radix Angelicae Pubescentis, Rhizoma Arisaematis, the requirement that breast is not processed by medicine physics and chemistry big gun cleans big gun and processs, then, according to production and processing amount size, enlarge drug ratios by various content of medicines in the above-mentioned prescription composition.Take by weighing to mix thoroughly and add in the 70% ethanol liquid, (ethanol exceeds medical material face 10～15cm, medical material all is immersed in the ethanol), soaked 20 days, incline alcoholic solution after, add 70% ethanol liquid again and soaked 20 days, inclining the immersion alcoholic solution again, this moment, the leachate with twice merged, filter with 100 mesh sieves, camphorate in the filtrate, 2 kinds of medicines of Borneolum Syntheticum stir evenly and soak after 20 days, can become externally-applied liniment of the present invention, bottle or container with different size carry out coating-dividing sealing, open bottle cap during use, are stained with this medicinal liquid with Cotton Gossypii, be coated with and put on the skin, reach the purpose of disease preventing and treating by the osmosis of medicine at human body certain acupuncture point or diseased region.
The present invention is except that above-mentioned processing technology technology, also can be according to the present invention various medicament contgs in the prescription composition of medicine, according to the Pharmacopoeia of the People's Republic of China and " pharmaceutical preparation handbook or new technology of preparation method, processing preparation are produced the external medicine preparation of the present invention of multiple different dosage form, different size.
The present invention shows through pharmacological research, having cold, the recuperating depleted yang of loosing in warm muscle pain relieving, the temperature, cardiac stimulant diuresis, promoting blood circulation and removing blood stasis, The effects such as cholagogic defaecation, the detumescence of reducing phlegm can improve blood circulation, increase CF, and anticoagulation, reduction blood fat, blood glue The degree cholesterol, the immunity of raising body is prevented and treated angina pectoris, hemiplegia, diabetes, coronary heart disease, rheumatoid arthritis, Rheumatic heart disease, pain in waist and lower extremities, oedema, stomachache etc. have preferably effect.
Medicine bag of the present invention, plaster, liniment be through clinical thousands of patients' observation, and it is active, promoting blood circulation and removing blood stasis to have a warm muscle, Yin Yang balancing, Regulate the function of qi and blood. But swelling and pain relieving, anticoagulation, improve blood circulation, reduce blood viscosity, blood sugar, blood fat and cholesterol Increase CF, cardiac stimulant diuresis, make the blood vessel of obstruction can be rapidly unimpeded, the very fast removing of nuisance mass-energy in the body. To disease Sick treatment can take effect in 30 minutes, and is efficient 98.6%, and has no side effect. The advantage of maximum of the present invention is to use pure natural Medicine is made, and does not contain hormone, to the side effect that the stingless sentiment of skin is dyed, and short treating period, instant effect, the cure rate height, recurrence rate is low, Easy to use, the patient takes like a shot.
To rheumatoid arthritis, chronic muscular strain, chronic hepatitis, abdominal distension, angina pectoris, coronary heart disease, rheumatic heart disease, mammary gland Hyperplasia, hemiplegia, vasculitis, asthma, chronic nephritis, uremia, oedema, osteoproliferation, cervical spondylopathy, pain in waist and lower extremities, Leg is swollen, Lipid increase disease, diabetes, postpartum renal shutdown, dysmenorrhoea, hyperplasia of prostate, bed-wetting, the lower limb of the suffering from a deficiency of the kidney blood stasis such as not warm Cold of insufficiency type illness has unique prevention effect.
Claims (8)
1. the external used medicine of a treatment arthralgia-syndrome pain disease made from pure Chinese medicine, it is characterized in that: its medicament composing prescription composition contains Chinese medicine ingredients such as Herba Ephedrae, Radix Aconiti Preparata, Radix Aconiti Kusnezoffii Preparata, Ramulus Cinnamomi, Radix Angelicae Sinensis, Semen Persicae, Flos Carthami, Cortex Phellodendri, Radix Angelicae Pubescentis, Rhizoma Arisaematis, Radix Et Rhizoma Rhei, Camphora, each component medical herbs content of distinguishing the flavor of: (unit: gram) Herba Ephedrae 1 Radix Aconiti Preparata 2 Radix Aconiti Kusnezoffii Preparatas 2 Ramulus Cinnamomi 1 Radix Angelicae Sinensis 2 Semen Persicaes 1 Flos Carthami 1.2 Cortex Phellodendris 1 Radix Angelicae Pubescentis 1.2 Rhizoma Arisaematis 0.8 Radix Et Rhizoma Rhei 2 breasts do not have each 1 Borneolum Syntheticum, 0.03 Camphora 0.02
In actual production, can enlarge deal by above-mentioned each component medical herbs content ratio according to the size of volume of production, make different classes of external used medicines such as externally used medicine bag, plaster, liniment through certain processes.
2. according to the external used medicine of the described a kind of treatment arthralgia-syndrome pain disease made from Chinese medicine of claim 1, it is characterized in that its preparation method comprises the following steps:
(1) with each medical herbs respectively by the requirement that the medicine big gun is processed clean, big gun is processed, dry pulverizing, presses the content ratio batching in the prescription composition again, mix and stirred 80～100 mesh sieves.
(2) weigh up medicated powder 10～30 grams, or weigh up medicine by the required amount of reality.
(3) make with cotton and other material and make deck.
(4) make strip sheath band with cloth.
(5) medicated powder that weighs up is packed in the deck, promptly get externally used medicine bag of the present invention in the sheath band of again deck being packed into.
3. the external used medicine of the treatment arthralgia-syndrome pain disease that the pure Chinese medicine of a kind of usefulness according to claim 1 is made is characterized in that its preparation method comprises the following steps:
(1) Oleum sesami is put into pot, heating is endured out.
(2) Herba Ephedrae, Ramulus Cinnamomi, Radix Aconiti Preparata, Radix Aconiti Kusnezoffii Preparata, Radix Angelicae Sinensis, Rhizoma Arisaematis, Semen Persicae, Flos Carthami, Cortex Phellodendri, Radix Et Rhizoma Rhei, Radix Angelicae Pubescentis are assorted in the desired amount mixed thoroughly, drop into to temper in the oil cauldron to fluid and splash into Cheng Zhu in the water, that blows does not loose, and stops heating, and temperature is reduced to 260 ℃.
(3) after temperature in the oil cauldron is reduced to 260 ℃, will pulverize 80～100 mesh sieve plaster raw material Plumbum preparatiums (in right amount) and add the pot the inside, the limit edged stirs, and sprays into a little cold water and removes cigarette up to adding, and treats that temperature drops to 70 ℃.
When (4) treating that temperature drops to 70 ℃ in the oil cauldron, do not have powder to add Borneolum Syntheticum, Camphora, the breast of pulverizing 100 mesh sieves, stir, add cold water soak 24～48h again, take out thermoplastic then, the stand is applied to mounts on the backing material, promptly gets plaster of the present invention.
4. the external used medicine of the treatment arthralgia-syndrome pain disease that the pure Chinese medicine of a kind of usefulness according to claim 1 is made is characterized in that its preparation method comprises the following steps:
(1) Herba Ephedrae, Ramulus Cinnamomi, Radix Aconiti Kusnezoffii Preparata, Radix Aconiti Preparata, Radix Angelicae Sinensis, Semen Persicae, Flos Carthami, Cortex Phellodendri, Radix Et Rhizoma Rhei, Radix Angelicae Pubescentis, Rhizoma Arisaematis, big gun are processed oven dry and be ground into fine powder.
(2) medicated powder of pulverizing is moistening with 90% ethanol, put into percolator, gauze on the even dress cover in shop is put into 90% ethanol liquid and is soaked 24h, collects percolate, and is concentrated into the thick paste shape.
(3) Olibanum, Myrrha were pulverized 100 mesh sieves.
(4) with Camphora, Borneolum Syntheticum 95% dissolve with ethanol.
(5) the about raw material raw rubber of cream (by the amount of total dose 50%) is cut into strip and cleans oven dry, be pressed into the thick thin rubber sheet of 2～3mm, placed 24 hours.
(6) Colophonium (by the amount of total dose 50%), sheet rubber are put into agitator.
(7) 2 kilograms in gasoline (by the amount of total dose 70%) is dropped in the agitator that Colophonium, sheet rubber are housed stirred 30 minutes, left standstill restir 2 hours 24 hours.
(8) wintergreen oil 20 grams, lanoline 100 grams, vaseline 50 grams, zinc oxide (by the amount that accounts for total dose 70%), breast do not had powder, Camphora, Borneolum Syntheticum, alcoholic solution, the adding of Chinese medicine condensed cream is equipped with in the agitator of Colophonium, Borneolum Syntheticum, gasoline, stir more than 6 hours, filter with 80 mesh sieves, filtrate is left standstill a week, can spread out and be coated with, the medicine adhesive plaster volume that coats is cut into suitable size specification, conform to the plastics pharmaceutical film again and promptly get external cream of the present invention.
5. the external used medicine of the treatment arthralgia-syndrome pain disease that the pure Chinese medicine of a kind of usefulness according to claim 1 is made is characterized in that its preparation method comprises the following steps:
(1) each herbal medicine such as Herba Ephedrae, Ramulus Cinnamomi, Radix Aconiti Preparata, Radix Aconiti Kusnezoffii Preparata is cleaned, big gun is processed oven dry, add in the 70% ethanol liquid to soak 20 days.
(2) medicinal liquid (ethanol) that will soak 20 days inclines to, and adds 70% soak with ethanol again 20 days, and inclining alcoholic solution.
(3) twice leachate that inclines merged, filter with 100 mesh sieves.
(4) soaked 20 days stirring evenly in Camphora, the Borneolum Syntheticum adding filtrate, promptly get externally-applied liniment of the present invention.
6. the preparation method of the external used medicine of the treatment arthralgia-syndrome pain disease that the pure Chinese medicine of a kind of usefulness according to claim 1 is made, it is characterized in that: according to the prescription composition according to the Pharmacopoeia of the People's Republic of China and " pharmaceutical preparation handbook or new technology new method, processing preparation are produced the external used medicine of the present invention of multiple different dosage form, different size.
7. the external used medicine of the treatment arthralgia-syndrome pain disease of making according to the pure Chinese medicine of the described a kind of usefulness of claim 1～2 is characterized in that the profile of medicated bag and material color or big I make according to actual needs.
8. the external used medicine of the treatment arthralgia-syndrome pain disease of making according to claim 1 and the pure Chinese medicine of the described a kind of usefulness of claim 3～4, it is characterized in that plaster and mount the backing material, with kraft paper or cloth and permeability material preferably, the size specification of its plaster can be made according to actual needs.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 01136639 CN1277566C (en) | 2001-10-24 | 2001-10-24 | Method for preparing medicine for treatment of arthralgia-syndrome pain disease |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 01136639 CN1277566C (en) | 2001-10-24 | 2001-10-24 | Method for preparing medicine for treatment of arthralgia-syndrome pain disease |
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| Publication Number | Publication Date |
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| CN1413604A true CN1413604A (en) | 2003-04-30 |
| CN1277566C CN1277566C (en) | 2006-10-04 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 01136639 Expired - Fee Related CN1277566C (en) | 2001-10-24 | 2001-10-24 | Method for preparing medicine for treatment of arthralgia-syndrome pain disease |
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| CN (1) | CN1277566C (en) |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101612220B (en) * | 2009-07-21 | 2011-05-11 | 杭州市中医院 | External-application cream for treating osteoarthritis and preparation method thereof |
| CN101703646B (en) * | 2009-11-26 | 2011-05-25 | 黄远吉 | Externally applied Chinese medicine composition for treating hyperosteogeny |
| CN103239542A (en) * | 2013-05-10 | 2013-08-14 | 云南省中医医院 | Medicament for treating gouty arthritis prepared from traditional Chinese medicines and preparation method thereof |
| CN105362535A (en) * | 2014-08-08 | 2016-03-02 | 吴奇 | Rheumatalgia treating wet ointment |
| CN108379490A (en) * | 2018-05-16 | 2018-08-10 | 山东普林生物科技有限公司 | A kind of quick conditioning and treating women palace cold, dysmenorrhoea, cold body, trick ice-cold nanometer and small molecule Chinese medicine bath foam |
| CN108403874A (en) * | 2018-05-16 | 2018-08-17 | 陈朗 | A kind of vigor moisturizing mud and preparation method thereof |
| CN111214598A (en) * | 2020-01-23 | 2020-06-02 | 黎帝明 | A Chinese medicinal composition for treating rigidity of muscles and activating collaterals, traumatic injury and sprain, and rheumatalgia |
| CN111514238A (en) * | 2019-02-01 | 2020-08-11 | 曲振宇 | Externally-applied ointment for treating rheumatism and preparation method thereof |
| CN113855752A (en) * | 2021-11-11 | 2021-12-31 | 彭海 | A Chinese medicinal composition for treating osteoarticular diseases, and its preparation method |
-
2001
- 2001-10-24 CN CN 01136639 patent/CN1277566C/en not_active Expired - Fee Related
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101612220B (en) * | 2009-07-21 | 2011-05-11 | 杭州市中医院 | External-application cream for treating osteoarthritis and preparation method thereof |
| CN101703646B (en) * | 2009-11-26 | 2011-05-25 | 黄远吉 | Externally applied Chinese medicine composition for treating hyperosteogeny |
| CN103239542A (en) * | 2013-05-10 | 2013-08-14 | 云南省中医医院 | Medicament for treating gouty arthritis prepared from traditional Chinese medicines and preparation method thereof |
| CN105362535A (en) * | 2014-08-08 | 2016-03-02 | 吴奇 | Rheumatalgia treating wet ointment |
| CN108379490A (en) * | 2018-05-16 | 2018-08-10 | 山东普林生物科技有限公司 | A kind of quick conditioning and treating women palace cold, dysmenorrhoea, cold body, trick ice-cold nanometer and small molecule Chinese medicine bath foam |
| CN108403874A (en) * | 2018-05-16 | 2018-08-17 | 陈朗 | A kind of vigor moisturizing mud and preparation method thereof |
| CN111514238A (en) * | 2019-02-01 | 2020-08-11 | 曲振宇 | Externally-applied ointment for treating rheumatism and preparation method thereof |
| CN111214598A (en) * | 2020-01-23 | 2020-06-02 | 黎帝明 | A Chinese medicinal composition for treating rigidity of muscles and activating collaterals, traumatic injury and sprain, and rheumatalgia |
| CN113855752A (en) * | 2021-11-11 | 2021-12-31 | 彭海 | A Chinese medicinal composition for treating osteoarticular diseases, and its preparation method |
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| Publication number | Publication date |
|---|---|
| CN1277566C (en) | 2006-10-04 |
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Granted publication date: 20061004 Termination date: 20091124 |