CN101129588A - Medicinal granules for conjunctivitis - Google Patents

Medicinal granules for conjunctivitis Download PDF

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Publication number
CN101129588A
CN101129588A CNA2007101310096A CN200710131009A CN101129588A CN 101129588 A CN101129588 A CN 101129588A CN A2007101310096 A CNA2007101310096 A CN A2007101310096A CN 200710131009 A CN200710131009 A CN 200710131009A CN 101129588 A CN101129588 A CN 101129588A
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gram
concentrated
clear paste
conjunctivitis
radix
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CNA2007101310096A
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陈江
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Abstract

The invention relates to a medicament for reducing fever, removing intensive heat from the liver and improving acuity of sight and process for preparation, wherein the medicament is prepared mainly from Chinese herbs including mulberry leaf, wild chrysanthemum flower, clerodendroa cyrtophyllum, Schizonepeta tenuifolia, mentha, Chinese angelica root, dried rehmannia root, Ligusticum wallichii, cassia seed, peach kernels, safflower, raw licorice roots, broom cypress fruit, cicada shell. the medicament has good effect in treating epidemic hemorrhage conjunctivitis and eyelid itching.

Description

Medicinal granules for conjunctivitis
Technical field
The present invention relates to a kind of epidemic hemorrhagic conjunctivitis, eyelid electuary of the medicated diet combination of symptom and preparation method, especially cleaning heat and expelling wind, liver heat removing and eyesight improving such as itch for the treatment of.
Background technology
Conjunctivitis is meant that the conjunctiva of eyes infects virus or antibacterial and inflammation, it is the very strong disease of a kind of infectiousness, because the most of conjunctiva of eye directly contacts with extraneous, therefore be subjected in the surrounding infectious easily (as antibacterial, virus, and chlamydia etc.) and non-infectious factor (wound, chemical substance and physical factor etc.) stimulation, and the blood vessel of conjunctiva and lymphoid tissue are abundant, self and extraneous antigen make its sensitization easily, the general designation of the conjunctivitis inflammatory reaction that to be conjunctival tissue take place in the effect of extraneous and body oneself factor, itself is to eyesight influence and not serious, but when its inflammation involves cornea or leads to complications, can cause the infringement of vision.
Present treatment epidemic hemorrhagic conjunctivitis, the eyelid medicine of symptom such as itch, require repetitively administered, treatment is long the course of treatment, the chance that drug resistance reaction and toxic and side effects occur increases, compliance is also relatively poor, easily cause other complication, general biological preparation can not be satisfied the demand on therapeutic effect, palliate the agonizing sufferings for the patient better, the reasonable prescription of minority drug effect is also arranged and become agent, but the mode of the taking drug effect absorption difference of patent medicine does not reach the purpose of effective treatment, the safety of medicine performance is poor, is not accepted by the patient.
Summary of the invention
The purpose of this invention is to provide a kind of taking convenience, have no side effect, treat the effective electuary of conjunctivitis.
A kind of epidemic hemorrhagic conjunctivitis that is used for the treatment of; the eyelid electuary of symptom such as itch; become to be grouped into by plurality of Chinese; the technical scheme that is provided is: get Folium Mori; Flos Chrysanthemi; Folium Isatidis; Herba Schizonepetae; Herba Menthae; Radix Angelicae Sinensis; Radix Rehmanniae; Rhizoma Chuanxiong; each 10-15 gram of Semen Cassiae; Semen Persicae; each 5-7 gram of Flos Carthami; Radix Glycyrrhizae 2-4 gram; the Fructus Kochiae; each 8-10 gram of Periostracum Cicadae; sucrose is an amount of; after the clean system of selected medical material; go into the medicine cutter cutting; the pulverizing medicinal materials that cooks is a coarse powder; make solvent with 60% ethanol; percolation behind the dipping 24h; collect percolate; filter; be concentrated into the clear paste of relative density; the clean medical material back that feeds intake is decocted, be concentrated into the clear paste of relative density, two kinds of clear paste merge; filtrate carries out further concentrating; put into cylinder of steel when being concentrated into certain viscosity, add load weighted extractum, stir; cross 12 mesh sieves sieve grain after drying and cooling; granulate; granulate; behind the qualified granule mixing 12min that filters out, the sterilization of packing into; dry; in the airtight container, carry out the medicinal granules for conjunctivitis of outer package gained after packing with aluminum foil bag.
For realizing that preparation method provided by the present invention may further comprise the steps:
1, clean system: selected medical material is sieved away silt respectively, select the foreign material that fall to go mouldy, the medical material of needs washing is cleaned, change the medicine cutter cutting over to;
2, pulverize: getting the pulverizing medicinal materials that cooks is coarse powder, makees solvent with 60% ethanol, and percolation behind the dipping 24h is collected percolate, filters, and is concentrated into the clear paste of relative density, and residue is standby;
3, extract to concentrate: the clean medical material back that feeds intake is decocted, and suitable quantity of water decocts 2h for the first time, decocts 1h after adding residue for the second time, and merging filtrate is concentrated into the clear paste of relative density; Two kinds of clear paste merge, and filtrate carries out further concentrating, and put into cylinder of steel when being concentrated into certain viscosity;
4, pulverize batching: the saccharide of required pulverizing is pulverized, crossed 80 mesh sieves, put in the mixer, add load weighted extractum, stir;
5, granulate: with 12 mesh sieves sieve grain;
6, drying: baking temperature is about 80 ℃, the cooling in time of dry back;
7, granulate: cross 10 mesh sieve granulate;
8, sieve grain: the coarse grain and the fine powder that filter out are pulverized again, prepare burden, granulated;
9, the total mixing: behind the qualified granule mixing 12min that will filter out, in the sterilization of packing into, drying, the airtight container;
10, pack: carry out outer package after packing with aluminum foil bag;
Flos Chrysanthemi is the dry capitulum of feverfew Flos Chrysanthemi, is conventional Chinese medicine, the effect of have dispelling wind, heat clearing away, make eye bright, detoxifying, diseases such as main treatment headache, dizzy, conjunctival congestion, irritable feverish sensation of chest and heart, furuncle, toxic swelling.Modern pharmacological research shows, Flos Chrysanthemi has treatment coronary heart disease, brings high blood pressure down, prevents hyperlipidemia, antibiotic, antiviral, antiinflammatory, the anti-ageing multiple pharmacologically active of waiting for a long time:
1, cardiovascular aspect pharmacological action.The phenol position of Flos Chrysanthemi can increase the heart coronary flow, improves body to the anoxybiotic tolerance that reduces pressure, and the total extract of Flos Chrysanthemi all shows to have positive inotropic action to isolated heart, myocardial cell.
2, antivirus action.Flos Chrysanthemi is to herpes simplex virus, and poliovirus and Measles virus have inhibitory action in various degree; In addition, Flos Chrysanthemi also has the effect of anti-AIDS.
3, anti-aging effects.Flos Chrysanthemi can strengthen the glutathion peroxidating and reduce, and life-saving can also improve the heart and brain resisting oxygen lack, the ability that prolongs life span and remove free radical.
4, antitumor action.In the Flos Chrysanthemi there being than significant inhibitory effect to cutaneous tumor isolating effective ingredient, in addition human tumor cells such as kinds of tumor such as pulmonary carcinoma, colon cancer, renal carcinoma, ovarian cancer, the brain cancer, leukemia is had extremely significant cytotoxic activity.
The Fructus Kochiae is cold in nature, and acrid in the mouth, hardship have clearing away heat-damp and promoting diuresis, and the effect of dispelling wind for relieving itching is used for difficulty and pain in micturition, pudendal pruritus leukorrhagia, rubella, eczema, skin pruritus etc.
Semen Persicae removing blood stasis, loosening bowel to relieve constipation have anticoagulation, reduction blood stickiness, antiinflammatory, relieving constipation, antitussive, analgesic effect; Flos Carthami promoting blood circulation to restore menstrual flow, pain relieving blood stasis dispelling, effectively blood fat reducing, blood pressure lowering, coronary artery dilator;
The present invention compared with prior art, it need not be taken medicine, have an injection, also without hospitalization, taking convenience, and the pharmacy cost is low, and the pharmacotherapy more commonly used than doctor trained in Western medicine makes the patient satisfaction rate improve 30%, cure rate reaches 20%, effective percentage finds no any toxic and side effects more than 90%, and is especially remarkable to treatment epidemic hemorrhagic conjunctivitis, eyelid symptom effect such as itch; In addition, the present invention also can be used as the medicated diet commonly used of health care, has the effect of cleaning heat and expelling wind, liver heat removing and eyesight improving, is fit to Garments capable of wearing in four seasons usefulness, has no side effect, and better economic and social benefit are arranged.
Specific embodiments
In the actual pharmacy; can be with Folium Mori; Flos Chrysanthemi; Folium Isatidis; Herba Schizonepetae; Herba Menthae; Radix Angelicae Sinensis; Radix Rehmanniae; Rhizoma Chuanxiong; each 10-15 gram of Semen Cassiae; Semen Persicae; each 5-7 gram of Flos Carthami; Radix Glycyrrhizae 2-4 gram, the Fructus Kochiae; each 8-10 gram of Periostracum Cicadae, sucrose is an amount of; after the clean system of selected medical material; go into the medicine cutter cutting, the pulverizing medicinal materials that cooks is a coarse powder, makees solvent with 60% ethanol; percolation behind the dipping 24h; collect percolate, filter, be concentrated into the clear paste of relative density; the clean medical material back that feeds intake is decocted; be concentrated into the clear paste of relative density, two kinds of clear paste merge, and filtrate carries out further concentrating; put into cylinder of steel when being concentrated into certain viscosity; add load weighted extractum, stir, cross 12 mesh sieves sieve grain after drying and cooling; granulate; granulate; behind the qualified granule mixing 12min that filters out; the sterilization of packing into; dry; in the airtight container, carry out the medicinal granules for conjunctivitis of outer package gained after packing with aluminum foil bag, if white of the eye is significantly congested; photophobia eyeball pearl pain person adds Cortex Moutan; each 10 gram of Spica Prunellae are used as medicine.
Below in conjunction with embodiment content of the present invention is described further:
Embodiment one
Compatibility is: Folium Mori, Flos Chrysanthemi, Folium Isatidis, Herba Schizonepetae, Herba Menthae, Radix Angelicae Sinensis, Radix Rehmanniae, Rhizoma Chuanxiong, each 10-15 gram of Semen Cassiae, and Semen Persicae, each 5-7 gram of Flos Carthami, Radix Glycyrrhizae 2-4 gram, the Fructus Kochiae, each 8-10 gram of Periostracum Cicadae, sucrose is an amount of.
Preparation method:
1, clean system: selected medical material is sieved away silt respectively, select the foreign material that fall to go mouldy, the medical material of needs washing is cleaned, change the medicine cutter cutting over to;
2, pulverize: getting the pulverizing medicinal materials that cooks is coarse powder, makees solvent with 60% ethanol, and percolation behind the dipping 24h is collected percolate, filters, and is concentrated into the clear paste of relative density, and residue is standby;
3, extract to concentrate: the clean medical material back that feeds intake is decocted, and suitable quantity of water decocts 2h for the first time, decocts 1h after adding residue for the second time, and merging filtrate is concentrated into the clear paste of relative density; Two kinds of clear paste merge, and filtrate carries out further concentrating, and put into cylinder of steel when being concentrated into certain viscosity;
4, pulverize batching: the saccharide of required pulverizing is pulverized, crossed 80 mesh sieves, put in the mixer, add load weighted extractum, stir;
5, granulate: with 12 mesh sieves sieve grain;
6, drying: baking temperature is about 80 ℃, the cooling in time of dry back;
7, granulate: cross 10 mesh sieve granulate;
8, sieve grain: the coarse grain and the fine powder that filter out are pulverized again, prepare burden, granulated;
9, the total mixing: behind the qualified granule mixing 12min that will filter out, in the sterilization of packing into, drying, the airtight container;
10, pack: carry out outer package after packing with aluminum foil bag;
Embodiment two
Compatibility is: Folium Mori, Flos Chrysanthemi, Folium Isatidis, Herba Schizonepetae, Herba Menthae, Radix Angelicae Sinensis, Radix Rehmanniae, Rhizoma Chuanxiong, each 10-15 gram of Semen Cassiae, Semen Persicae, each 5-7 gram of Flos Carthami, Radix Glycyrrhizae 2-4 gram, the Fructus Kochiae, each 8-10 gram of Periostracum Cicadae, Cortex Moutan, each 10 gram of Spica Prunellae, sucrose is an amount of, and its preparation method is with embodiment one.
In sum, dose of the present invention can be divided into treatment and keep healthy two kinds, but divide 3 boiled water to take after mixing it with water every day for the patient, and each consumption 10 grams are not limit as ordinary person's medicated diet Time of Administration that keeps healthy, the present invention is without any side effects, drug safety performance height is taken but brew for 1 time every day, and the present invention is the yellow particle shape, EDD is 1-2, and each medicine in the compatibility and preparation method thereof is to select for use according to " Pharmacopoeia of People's Republic of China ".
The rationale of the present invention treatment is that Folium Mori, Flos Chrysanthemi, Folium Isatidis, Herba Schizonepetae, Herba Menthae, Radix Angelicae Sinensis, Radix Rehmanniae, Rhizoma Chuanxiong, Semen Cassiae, Semen Persicae, Flos Carthami, Radix Glycyrrhizae, the Fructus Kochiae, Periostracum Cicadae with cleaning heat and expelling wind, liver heat removing and eyesight improving etc. are as raw material, mode administration by electuary, show through clinical trial, the present invention has good antipyretic and antidote functions, effective percentage is more than 90%, for clinical treatment epidemic hemorrhagic conjunctivitis, eyelid symptom such as itch provides strong foundation.

Claims (2)

1. medicinal granules for conjunctivitis; it is characterized in that Folium Mori; Flos Chrysanthemi; Folium Isatidis; Herba Schizonepetae; Herba Menthae; Radix Angelicae Sinensis; Radix Rehmanniae; Rhizoma Chuanxiong; each 10-15 gram of Semen Cassiae; Semen Persicae; each 5-7 gram of Flos Carthami; Radix Glycyrrhizae 2-4 gram; the Fructus Kochiae; each 8-10 gram of Periostracum Cicadae, sucrose is an amount of, after the clean system of selected medical material; go into the medicine cutter cutting; the pulverizing medicinal materials that cooks is a coarse powder, makees solvent with 60% ethanol, percolation behind the dipping 24h; collect percolate; filter, be concentrated into the clear paste of relative density, decoct after clean medical material is fed intake; be concentrated into the clear paste of relative density; two kinds of clear paste merge, and filtrate carries out further concentrating, and put into cylinder of steel when being concentrated into certain viscosity; add load weighted extractum; stir, cross 12 mesh sieves sieve grain after drying and cooling; granulate; granulate, behind the qualified granule mixing 12min that filters out; the sterilization of packing into; dry; in the airtight container, carry out the product of outer package gained after packing with aluminum foil bag.
2. according to claim 1, it is characterized in that formulation ratio consists of Folium Mori, Flos Chrysanthemi, Folium Isatidis, Herba Schizonepetae, Herba Menthae, Radix Angelicae Sinensis, Radix Rehmanniae, Rhizoma Chuanxiong, each 10-15 gram of Semen Cassiae, Semen Persicae, each 5-7 gram of Flos Carthami, Radix Glycyrrhizae 2-4 gram, the Fructus Kochiae, each 8-10 gram of Periostracum Cicadae, Cortex Moutan, each 10 gram of Spica Prunellae, sucrose is an amount of.
CNA2007101310096A 2007-08-20 2007-08-20 Medicinal granules for conjunctivitis Pending CN101129588A (en)

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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102631539A (en) * 2012-04-23 2012-08-15 常州亚环环保科技有限公司 Chinese patent medicine for treating trachoma and preparation method thereof
CN103566059A (en) * 2013-10-22 2014-02-12 重庆市中药研究院 Liver-protecting eyesight-improving folium isatidis and semen cassiae drug pair combined medicament, preparation method and application thereof
CN103735721A (en) * 2014-01-21 2014-04-23 张学峰 Traditional Chinese medicine for treating acute infectious conjunctivitis
CN104225300A (en) * 2014-08-30 2014-12-24 孟钧 Traditional Chinese medicine preparation for treating membranous conjunctivitis
CN104800337A (en) * 2015-05-15 2015-07-29 青岛辰达生物科技有限公司 Medicine composition for treating spring conjunctivitis
CN104888015A (en) * 2015-06-18 2015-09-09 王峰 Oral traditional Chinese medicine for treating conjunctivitis
CN104922518A (en) * 2015-06-18 2015-09-23 王峰 Traditional Chinese medicine composition for treating conjunctivitis
CN106138182A (en) * 2015-03-31 2016-11-23 刘宽明 A kind of formula controlling pink eye disease

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102631539A (en) * 2012-04-23 2012-08-15 常州亚环环保科技有限公司 Chinese patent medicine for treating trachoma and preparation method thereof
CN103566059A (en) * 2013-10-22 2014-02-12 重庆市中药研究院 Liver-protecting eyesight-improving folium isatidis and semen cassiae drug pair combined medicament, preparation method and application thereof
CN103566059B (en) * 2013-10-22 2016-08-17 重庆市中药研究院 A kind of blue or green certainly liver-nourishing and eyesight-improving medicine is to composition of medicine, preparation method and applications
CN103735721A (en) * 2014-01-21 2014-04-23 张学峰 Traditional Chinese medicine for treating acute infectious conjunctivitis
CN103735721B (en) * 2014-01-21 2016-06-08 张学峰 A kind of Chinese medicine treating pink-eye
CN104225300A (en) * 2014-08-30 2014-12-24 孟钧 Traditional Chinese medicine preparation for treating membranous conjunctivitis
CN106138182A (en) * 2015-03-31 2016-11-23 刘宽明 A kind of formula controlling pink eye disease
CN104800337A (en) * 2015-05-15 2015-07-29 青岛辰达生物科技有限公司 Medicine composition for treating spring conjunctivitis
CN104888015A (en) * 2015-06-18 2015-09-09 王峰 Oral traditional Chinese medicine for treating conjunctivitis
CN104922518A (en) * 2015-06-18 2015-09-23 王峰 Traditional Chinese medicine composition for treating conjunctivitis

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Open date: 20080227