CN104922518A - Traditional Chinese medicine composition for treating conjunctivitis - Google Patents
Traditional Chinese medicine composition for treating conjunctivitis Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for treating conjunctivitis and a preparation method thereof. The traditional Chinese medicine composition for treating conjunctivitis is prepared by, by weight proportion, the main drug substances of 12-18 parts of angelica sinensis, 10-15 parts of meadowrue root and rhizome, 8-13 parts of eriocaulon buergerianum, 6-12 parts of youngia japonica, 9-14 parts of waxgourd seeds, 11-16 parts of chinese dicliptera herbs, 10-17 parts of prunella vulgaris, 7-13 parts of shady groundsel herbs, 6-9 parts of flowers carthami, 8-12 parts of japanese polygala, 10-44 parts of lophatherum gracile, 7-12 parts of herba fibraureae recisae, 9-13 parts of hypericum monogynum, 10-16 parts of caulis akebiae and 12-16 parts of zornia diphylla. According to the traditional Chinese medicine composition, drug resistance cannot be generated, safety is achieved, no side effects exist, diseases can be eliminated fundamentally and are not prone to relapsing, the treatment period is short, and the treatment effect is remarkable.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of Chinese medicine composition and method for making thereof for the treatment of conjunctivitis.
Background technology
The general designation of the conjunctivitis inflammatory reaction that to be conjunctival tissue occur in the effect of extraneous and body oneself factor.Although conjunctivitis itself is not serious to eyesight influence, when its inflammation involves cornea or leads to complications, the infringement of vision can be caused.According to the state of an illness and the course of disease of conjunctivitis, acute, subacute and chronic three classes can be divided into; Bacillary, viral, chlamydial, fungoid and allergy etc. can be divided into again according to the cause of disease; According to the lesion characteristic of conjunctiva, acute follicular conjunctivitis, chronic follicular conjunctivitis, film and pseudomembranous conjunctivitis etc. can be divided into.The cause of disease of conjunctivitis can be divided into infectious and non-infectious two large classes according to its heterogeneity.1. infectious: the conjunctiva inflammation caused by cause pathogeny imcrobe infection.2. non-infectious: the most common with the allergic inflammation that local or the allergy of whole body cause, extraneous chemical factors, as light, various chemical substance also can become paathogenic factor.Conjunctival congestion and secretions increase are the common features of various conjunctivitis, and inflammation can be simple eye or eyes while/first sequela., photophobia can be there is when pathological changes involves cornea, shed tears and visual deterioration in various degree in symptom: suffer from that eye foreign body sense, burn feeling, eyelid are heavy, secretions increase.Sign: the sign of conjunctivitis is the important evidence of the various different conjunctivitis of correct diagnosis.(1) conjunctival congestion: the feature of the conjunctiva congestion of blood vessel is that nearer fornices hyperemia is more obvious, and blood vessel is net distribution, and color is scarlet, can stretch into cornea periphery and form corneal pannus, drip and disappear very soon with hyperemia after epinephrine.(2) secretions: purulent secretion is more common in gonococcal conjunctivitis; Mucosa purulence or Catarrhal secretions are more common in bacillary or chlamydial conjunctivitis, often firmly can stick at eyelashes, make to play eyelid morning and open difficulty; Watery secretion sees viral conjunctivitis usually.(3) chemosis: conjunctiva inflammation causes conjunctiva vasodilation, ooze out and cause tissue edema, because of bulbar conjunctiva and fornical conjunctiva organizational slack, during edema, protuberance obviously.(4) subconjunctival hemorrhage: mostly be point-like or strip, virogenetic epidemic hemorrhagic conjunctivitis often can accompany subconjunctival hemorrhage.(5) nipple: the non-specific sign being conjunctiva inflammation, can be positioned at palpebral conjunctiva or limbus of corneae, shows as the polygon mosaic sample outward appearance of protuberance, congested region be separated by pale ditch gap.(6) folliculus: folliculus is yellow-white, smooth rounded protuberance, diameter 0.5 ~ 2.0mm, but in some cases as chlamydial conjunctivitis, also can occur larger folliculus; Viral conjunctivitis and chlamydial conjunctivitis Chang Yin are formed with obvious folliculus, are called as acute follicular conjunctivitis or chronic follicular conjunctivitis.(7) film and pseudomembrane: film is that the cellulose being attached to conjunctival surface oozes out, pseudomembrane is easy to peel off, and true film is not easily separated, after peeling off by force, wound surface is hemorrhage, the difference of the two essence is the difference of inflammatory reaction degree, the inflammatory reaction of true film is more violent, and diphtheria corynebacterium causes serious membranous conjunctivitis; Beta hemolytic streptococcus, pneumobacillus, gonococcus, adenovirus, inclusion body etc. all can cause film or pseudomembranous conjunctivitis.(8) cicatrix: the damage of matrix organization is the histological basis that conjunctival scar is formed.Early stage conjunctival scarization performance has fibrosis under retrotarsal fold portion constriction and conjunctival epithelium.(9) preauricular lymph nodes enlargement: viral conjunctivitis is often with preauricular lymph nodes enlargement.(10) pseudoptosis: because cellular infiltration or cicatrization make upper eyelid tissue plump, cause the slight ptosis, is more common in trachoma late period.(11) conjunctival granuloma: more rare, is found in the chronic inflammatory disease that tuberculosis, leprosy, syphilis and rickettsia etc. cause.
Treatment: 1. topical therapeutic: (1) rinses conjunctival sac.Its effect is mainly cleaned, and dust head is normal saline, 2% ~ 3% canopy acid solution or 1:5000 ~ 1:10000 mercuric chloride (or potassium permanganate) solution.(2) trouble eye is hidden.Because secretions during conjunctivitis is a lot, if suffering from eye-shade lid, secretions is not easily discharged, and collection is stored in conjunctival sac; And conjunctival sac temperature can be made to raise after hiding, be more conducive to the breeding of antibacterial, conjunctivitis is aggravated.(3) local application.Antibacterials or antiviral eye drop, according to etiological diagnosis, select corresponding medicine.Conventional 0.5% ~ 1% silver nitrate, will overturn eyelid during eye drip, by eye drop in palpebral conjunctiva, slightly stops a moment, namely use normal saline flushing after eye drip.Or dip in a small amount of medicinal liquid with cotton swab, be applied to palpebral conjunctiva surface, use normal saline flushing immediately.2. whole body therapeutic.For serious conjunctivitis, as gonococcal conjunctivitis, trachoma etc., need treat in conjunction with systemic administration.
Application publication number CN 104415182 A(application number 201310379134.4) Chinese patent literature disclose a kind of Chinese medicine formula for the treatment of conjunctivitis, be made up of the raw material of Chinese medicine of following weight proportioning: Herba Senecionis Scandentis 10-15, Hepar Sus domestica 10-15, Rhizoma Atractylodis 20-30, Fructus Forsythiae 20-30, Herba Houttuyniae 20-40, Folium Mori 20-40, Flos Chrysanthemi 20-40, Periostracum Cicadae 10-20, Flos Eriocauli 20-40.Application publication number CN 104027750 A(application number 201410301466.5) Chinese patent literature disclose a kind of Chinese medicine for the treatment of conjunctivitis.This Chinese medicine is made up of the raw material of following weight parts proportioning: Cortex Phellodendri 8, Flos Chrysanthemi 9, Fructus Forsythiae 10, Radix Paeoniae Rubra 7, Herba Menthae 9, Radix Glycyrrhizae 6, Semen Plantaginis 6, Flos Carthami 8, Rhizoma Coptidis 12, Radix Angelicae Sinensis 11, Herba Leonuri 9, Folium Pyrrosiae 13, Rhizoma Curcumae 11, Radix Clematidis 12, Talcum 10, Radix Puerariae 8, Pheretima 7, Flos Sophorae 15, Radix Stephaniae Tetrandrae 12, Rhizoma Corydalis 13, Ramulus Uncariae Cum Uncis 9, Caulis Spatholobi 10, Radix Aconiti Lateralis Preparata 12, Rhizoma Alismatis 14, Poria 10, Radix Asteris 9, Fructus Gardeniae 8, Herba Dendrobii 7, Fructus Crataegi 12, Radix Codonopsis 9, Semen Abutili 8, the Cortex Eucommiae 7, Herba Taxilli 9.Application publication number CN 104491562 A(application number 201510022100.9) Chinese patent literature disclose a kind of Chinese medicine composition for the treatment of conjunctivitis.This Chinese medicine composition is made up of Flos Chrysanthemi, Fructus Viticis, Flos Eriocauli, Spina Gleditsiae, Rhizoma Paridis, Rhizoma Phragmitis, Rhizoma Pinelliae, Spica Prunellae, Semen Cassiae, Nidus Vespae, Radix Cynanchi Paniculati, Fructus Zanthoxyli Ailanthoidis, Radix Stephaniae Tetrandrae, the Fructus Kochiae and Semen Benincasae.
At present, mainly carry out topical therapeutic with the eye drop of antibiotics to the treatment of conjunctivitis, the course for the treatment of of treatment is longer, and curative effect is undesirable, and uses antibiotic too much easily to cause virus to produce drug resistance.In addition, frequent eye drip affects tear film mucus albumen to the adhesion function of eye table epithelium, and tear film stability is declined, then occurs the senses of discomfort such as eye burns, dry and astringent, side effect is large.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide a kind of Chinese medicine composition and method for making thereof for the treatment of conjunctivitis.The present invention can not produce drug resistance, safely, has no side effect, and fundamentally can eliminate sufferer, not easily recur, short treating period, evident in efficacy.
Technical scheme of the present invention is:
Treat a Chinese medicine composition for conjunctivitis, take off the primary raw material medicine stating weight proportion and be prepared from: Radix Angelicae Sinensis 12-18, Radix et Rhizoma Thalictri 10-15, Flos Eriocauli 8-13, Herba youngiae japonicae 6-12, Semen Benincasae 9-14, Herba Diclipterae Chinensis 11-16, Spica Prunellae 10-17, Herba senecionis nemorensis 7-13, Flos Carthami 6-9, Herba Polygalae Japonicae 8-12, Herba Lophatheri 10-14, Caulis Fibraureae 7-12, Radix Hyperici Monogyni (Herba Hyperici Monogyni) 9-13, Caulis Akebiae 10-16, Herba Zornia Diphyllae 12-16.
Treat a Chinese medicine composition for conjunctivitis, preferred scheme is, takes off the primary raw material medicine stating weight proportion and is prepared from: Radix Angelicae Sinensis 14-16, Radix et Rhizoma Thalictri 11-14, Flos Eriocauli 9-12, Herba youngiae japonicae 8-11, Semen Benincasae 10-12, Herba Diclipterae Chinensis 12-14, Spica Prunellae 12-14, Herba senecionis nemorensis 9-11, Flos Carthami 7-8, Herba Polygalae Japonicae 9-11, Herba Lophatheri 11-13, Caulis Fibraureae 8-10, Radix Hyperici Monogyni (Herba Hyperici Monogyni) 10-12, Caulis Akebiae 13-15, Herba Zornia Diphyllae 13-15.
Treat a Chinese medicine composition for conjunctivitis, the scheme be more preferably is, takes off the primary raw material medicine stating weight proportion and is prepared from: Radix Angelicae Sinensis 15, Radix et Rhizoma Thalictri 12, Flos Eriocauli 11, Herba youngiae japonicae 10, Semen Benincasae 11, Herba Diclipterae Chinensis 13, Spica Prunellae 13, Herba senecionis nemorensis 10, Flos Carthami 7.5, Herba Polygalae Japonicae 10, Herba Lophatheri 12, Caulis Fibraureae 9, Radix Hyperici Monogyni (Herba Hyperici Monogyni) 11, Caulis Akebiae 14, Herba Zornia Diphyllae 14.
Present invention also offers the preparation method Chinese medicine composition of aforementioned therapies conjunctivitis being made pharmaceutically acceptable granule, pill, Tablet and Capsula agent.
The preparation method of described granule is:
(1) Herba Lophatheri is got, put into marmite, add 80-90 DEG C of boiling water (preferably adding 85 DEG C of boiling water), the amount of boiling water is 8-15 times (amount of preferred boiling water is 12 times of Herba Lophatheri weight) of Herba Lophatheri weight, soak 5-10 minute (preferably soaking 7 minutes), after boiling with high heat, turn slow fire boiling 18-26 minute (preferably turning slow fire boiling 24 minutes), leach soup, be condensed into the thick paste (being preferably condensed into the thick paste that relative density is 1.35) that relative density is 1.33-1.36,60 DEG C of dryings 14 hours, are ground into fine powder, cross 130 mesh sieves;
(2) get Caulis Fibraureae, add the yellow wine (preferably adding the yellow wine of Caulis Fibraureae weight 28%) of Caulis Fibraureae weight 25%-32%, mix thoroughly, put into and steam container, steam 2.2-3.5 hour (preferably steaming 2.9 hours with big fire) with big fire, take out, dry, be ground into fine powder, cross 130 mesh sieves;
(3) all the other the 13 taste crude drug except Herba Lophatheri and Caulis Fibraureae are put into 55 DEG C of thermostatic drying chambers, dry 4-8 hour (preferably dry 6 hours), take out, grind to the powder altogether, cross 130 mesh sieves;
(4) step (1), step (2) and step (3) gained are mixed, add step (1), step (2) and step (3) gained gross weight 0.6-1 amylum pregelatinisatum (preferably adding the amylum pregelatinisatum of step (1), step (2) and step (3) gained gross weight 0.8 times) doubly, mixing, be pressed into thin slice, be ground into granule, obtain final product.
The preparation method of described pill is:
(1) Herba Lophatheri is got, put into marmite, add 80-90 DEG C of boiling water (preferably adding 85 DEG C of boiling water), the amount of boiling water is 8-11 times (amount of preferred boiling water is 9 times of Herba Lophatheri weight) of Herba Lophatheri weight, soak 3-8 minute (preferably soaking 5 minutes), after boiling with high heat, turn slow fire boiling 15-25 minute (preferably turning slow fire boiling 20 minutes), leach soup;
(2) get Caulis Fibraureae, add the yellow wine (preferably adding the yellow wine of Caulis Fibraureae weight 28%) of Caulis Fibraureae weight 25%-32%, mix thoroughly, put into and steam container, steam 2.2-3.5 hour (preferably steaming 2.9 hours with big fire) with big fire, take out, dry, be ground into fine powder, cross 150 mesh sieves;
(3) all the other the 13 taste crude drug except Herba Lophatheri and Caulis Fibraureae are put into 55 DEG C of thermostatic drying chambers, dry 4-8 hour (preferably dry 6 hours), take out, grind to the powder altogether, cross 150 mesh sieves;
(4) by step (2) and the mixing of step (3) gained, with the general ball of step (1) gained, 45 DEG C of dryings 10 hours, the heavy 0.2g of every ball, to obtain final product.
The preparation method of described tablet is:
(1) Herba Lophatheri is got, put into marmite, add 80-90 DEG C of boiling water (preferably adding 85 DEG C of boiling water), the amount of boiling water is 8-15 times (amount of preferred boiling water is 12 times of Herba Lophatheri weight) of Herba Lophatheri weight, soak 5-10 minute (preferably soaking 7 minutes), after boiling with high heat, turn slow fire boiling 18-26 minute (preferably turning slow fire boiling 24 minutes), leach soup, be condensed into the thick paste (being preferably condensed into the thick paste that relative density is 1.35) that relative density is 1.33-1.36,60 DEG C of dryings 14 hours, are ground into fine powder, cross 130 mesh sieves;
(2) get Caulis Fibraureae, add the yellow wine (preferably adding the yellow wine of Caulis Fibraureae weight 28%) of Caulis Fibraureae weight 25%-32%, mix thoroughly, put into and steam container, steam 2.2-3.5 hour (preferably steaming 2.9 hours with big fire) with big fire, take out, dry, be ground into fine powder, cross 130 mesh sieves;
(3) all the other the 13 taste crude drug except Herba Lophatheri and Caulis Fibraureae are put into 55 DEG C of thermostatic drying chambers, dry 4-8 hour (preferably dry 6 hours), take out, grind to the powder altogether, cross 130 mesh sieves;
(4) step (1), step (2) and step (3) gained are mixed, add step (1), step (2) and step (3) gained gross weight 0.6-1 amylum pregelatinisatum (preferably adding the amylum pregelatinisatum of step (1), step (2) and step (3) gained gross weight 0.8 times) doubly, mixing, be pressed into thin slice, be ground into granule, tabletting, the heavy 0.4g of every sheet, to obtain final product.
The preparation method of described capsule is:
(1) Herba Lophatheri is got, put into marmite, add 80-90 DEG C of boiling water (preferably adding 85 DEG C of boiling water), the amount of boiling water is 8-15 times (amount of preferred boiling water is 12 times of Herba Lophatheri weight) of Herba Lophatheri weight, soak 5-10 minute (preferably soaking 7 minutes), after boiling with high heat, turn slow fire boiling 18-26 minute (preferably turning slow fire boiling 24 minutes), leach soup, be condensed into the thick paste (being preferably condensed into the thick paste that relative density is 1.35) that relative density is 1.33-1.36,60 DEG C of dryings 14 hours, are ground into fine powder, cross 130 mesh sieves;
(2) get Caulis Fibraureae, add the yellow wine (preferably adding the yellow wine of Caulis Fibraureae weight 28%) of Caulis Fibraureae weight 25%-32%, mix thoroughly, put into and steam container, steam 2.2-3.5 hour (preferably steaming 2.9 hours with big fire) with big fire, take out, dry, be ground into fine powder, cross 130 mesh sieves;
(3) all the other the 13 taste crude drug except Herba Lophatheri and Caulis Fibraureae are put into 55 DEG C of thermostatic drying chambers, dry 4-8 hour (preferably dry 6 hours), take out, grind to the powder altogether, cross 140 mesh sieves;
(4) step (1), step (2) and step (3) gained are mixed, add step (1), step (2) and step (3) gained gross weight 0.6-1 amylum pregelatinisatum (preferably adding the amylum pregelatinisatum of step (1), step (2) and step (3) gained gross weight 0.8 times) doubly, mixing, be pressed into thin slice, be ground into granule, load No. 1 capsule, every capsules is equipped with granule 0.32g, to obtain final product.
Chinese medicine composition scientific formula provided by the invention, the preparation method of various dosage form is simple, products obtained therefrom taking convenience, is easy to carry.In addition, excellent results of the present invention also shows:
1, drug resistance can not be produced;
, have no side effect 2, safely;
3, there is wind and heat eliminating, improving eyesight relieved inflammation or internal heat, effect of clearing away heat and expelling pathogen in the exterior, eliminating stasis to stop pain, eliminating fire and detoxication, improving acuity of vision and removing nebula, fundamentally can eliminate sufferer, not easily recur;
4, short treating period, evident in efficacy;
5, medicine source is easy to get, and cheap.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
embodiment 1treat a Chinese medicine composition for conjunctivitis, the primary raw material medicine getting following weight parts is prepared from (every part is 300g): Radix Angelicae Sinensis 12 parts, Radix et Rhizoma Thalictri 10 parts, Flos Eriocauli 8 parts, Herba youngiae japonicae 6 parts, Semen Benincasae 9 parts, Herba Diclipterae Chinensis 11 parts, Spica Prunellae 10 parts, Herba senecionis nemorensis 7 parts, 6 parts, Flos Carthami, Herba Polygalae Japonicae 8 parts, Herba Lophatheri 10 parts, Caulis Fibraureae 7 parts, Radix Hyperici Monogyni (Herba Hyperici Monogyni) 9 parts, Caulis Akebiae 10 parts, Herba Zornia Diphyllae 12 parts.
The preparation method of the Chinese medicinal composition granules of above-mentioned treatment conjunctivitis is:
(1) get Herba Lophatheri, put into marmite, add 80 DEG C of boiling water, the amount of boiling water is 8 times of Herba Lophatheri weight, soak 5 minutes, after boiling with high heat, turn slow fire boiling 18 minutes, leach soup, be condensed into the thick paste that relative density is 1.33,60 DEG C of dryings 14 hours, are ground into fine powder, cross 130 mesh sieves;
(2) get Caulis Fibraureae, add the yellow wine of Caulis Fibraureae weight 25%, mix thoroughly, put into and steam container, steam 2.2 hours with big fire, take out, dry, be ground into fine powder, cross 130 mesh sieves;
(3) all the other the 13 taste crude drug except Herba Lophatheri and Caulis Fibraureae are put into 55 DEG C of thermostatic drying chambers, dry 4 hours, take out, grind to the powder altogether, cross 130 mesh sieves;
(4) step (1), step (2) and step (3) gained are mixed, add the amylum pregelatinisatum of step (1), step (2) and step (3) gained gross weight 0.6 times, mixing, is pressed into thin slice, is ground into granule, to obtain final product.
The instructions of taking of the Chinese medicinal composition granules of above-mentioned treatment conjunctivitis is: oral, and three times on the one, each 10g, boiled water is taken after mixing it with water.
embodiment 2treat a Chinese medicine composition for conjunctivitis, the primary raw material medicine getting following weight parts is prepared from (every part is 300g): Radix Angelicae Sinensis 18 parts, Radix et Rhizoma Thalictri 15 parts, Flos Eriocauli 13 parts, Herba youngiae japonicae 12 parts, Semen Benincasae 14 parts, Herba Diclipterae Chinensis 16 parts, Spica Prunellae 17 parts, Herba senecionis nemorensis 13 parts, 9 parts, Flos Carthami, Herba Polygalae Japonicae 12 parts, Herba Lophatheri 14 parts, Caulis Fibraureae 12 parts, Radix Hyperici Monogyni (Herba Hyperici Monogyni) 13 parts, Caulis Akebiae 16 parts, Herba Zornia Diphyllae 16 parts.
The preparation method of the Chinese medicine composition pill of above-mentioned treatment conjunctivitis is:
(1) get Herba Lophatheri, put into marmite, add 85 DEG C of boiling water, the amount of boiling water is 9 times of Herba Lophatheri weight, soaks 5 minutes, after boiling with high heat, turns slow fire boiling 20 minutes, leach soup;
(2) get Caulis Fibraureae, add the yellow wine of Caulis Fibraureae weight 28%, mix thoroughly, put into and steam container, steam 2.9 hours with big fire, take out, dry, be ground into fine powder, cross 150 mesh sieves;
(3) all the other the 13 taste crude drug except Herba Lophatheri and Caulis Fibraureae are put into 55 DEG C of thermostatic drying chambers, dry 6 hours, take out, grind to the powder altogether, cross 150 mesh sieves;
(4) by step (2) and the mixing of step (3) gained, with the general ball of step (1) gained, 45 DEG C of dryings 10 hours, the heavy 0.2g of every ball, to obtain final product.
model case one:grandson XX, female, 46 years old.Main suit: suffer from conjunctivitis more than 1 year.Before 1 year, there is the scorching hot swelling pain of eyes eye in patient, the symptoms such as scratchy friendship work.To examination in hospital, be diagnosed as conjunctivitis.Once Drug therapy was carried out, without being clearly better.On July 11st, 2011 examines.Patient's inner canthus is itched very, and hyperemia of the bulbar conjunctiva is shed tears, burning sensation, photophobia, and secretions increases, and aversion to wind, red tongue is thin, the micro-Huang of thin fur, stringy and thready pulse, conjunctival congestion edema.Be diagnosed as conjunctivitis.Take the Chinese medicine composition pill of the present embodiment gained treatment conjunctivitis, one day twice, each 6 balls, warm water took.Take 5 days, symptom is obviously improved.Continue to take 5 days, all diseases disappear.Follow up a case by regular visits to and have no recurrence.
embodiment 3treat a Chinese medicine composition for conjunctivitis, the primary raw material medicine getting following weight parts is prepared from (every part is 300g): Radix Angelicae Sinensis 14 parts, Radix et Rhizoma Thalictri 11 parts, Flos Eriocauli 9 parts, Herba youngiae japonicae 8 parts, Semen Benincasae 10 parts, Herba Diclipterae Chinensis 12 parts, Spica Prunellae 12 parts, Herba senecionis nemorensis 9 parts, 7 parts, Flos Carthami, Herba Polygalae Japonicae 9 parts, Herba Lophatheri 11 parts, Caulis Fibraureae 8 parts, Radix Hyperici Monogyni (Herba Hyperici Monogyni) 10 parts, Caulis Akebiae 13 parts, Herba Zornia Diphyllae 13 parts.
The preparation method of the Chinese medicine composition tablet of above-mentioned treatment conjunctivitis is:
(1) get Herba Lophatheri, put into marmite, add 85 DEG C of boiling water, the amount of boiling water is 12 times of Herba Lophatheri weight, soak 7 minutes, after boiling with high heat, turn slow fire boiling 24 minutes, leach soup, be condensed into the thick paste that relative density is 1.35,60 DEG C of dryings 14 hours, are ground into fine powder, cross 130 mesh sieves;
(2) get Caulis Fibraureae, add the yellow wine of Caulis Fibraureae weight 28%, mix thoroughly, put into and steam container, steam 2.9 hours with big fire, take out, dry, be ground into fine powder, cross 130 mesh sieves;
(3) all the other the 13 taste crude drug except Herba Lophatheri and Caulis Fibraureae are put into 55 DEG C of thermostatic drying chambers, dry 6 hours, take out, grind to the powder altogether, cross 130 mesh sieves;
(4) step (1), step (2) and step (3) gained are mixed, add the amylum pregelatinisatum of step (1), step (2) and step (3) gained gross weight 0.8 times, mixing, is pressed into thin slice, is ground into granule, tabletting, and the heavy 0.4g of every sheet, to obtain final product.
model case two:high XX, man, 28 years old.Main suit: suffer from more than conjunctivitis JIUYUE.Before 9 months, patient occurs that ophthalmalgia difficulty is opened, the symptoms such as adversion to heat and photophobia.Go to a doctor to nearby hospitals, be diagnosed as conjunctivitis.Once eye drop was used to treat, poor effect.On February 18th, 2012 examines.Patient's ophthalmalgia difficulty is opened, adversion to heat and photophobia, a lot of sticky and yellow secretion in the eye, and eyelid is red and swollen, conjunctival congestion, edema, red tongue with yellow fur, rapid pulse.Be diagnosed as conjunctivitis.Take the Chinese medicine composition tablet of the present embodiment gained treatment conjunctivitis, one day twice, each 2, warm water took.Take 3 days, above-mentioned symptom is clearly better.Continue to take 5 days, all transference cures.Follow up a case by regular visits to and do not recur.
embodiment 4treat a Chinese medicine composition for conjunctivitis, the primary raw material medicine getting following weight parts is prepared from (every part is 300g): Radix Angelicae Sinensis 16 parts, Radix et Rhizoma Thalictri 14 parts, Flos Eriocauli 12 parts, Herba youngiae japonicae 11 parts, Semen Benincasae 12 parts, Herba Diclipterae Chinensis 14 parts, Spica Prunellae 14 parts, Herba senecionis nemorensis 11 parts, 8 parts, Flos Carthami, Herba Polygalae Japonicae 11 parts, Herba Lophatheri 13 parts, Caulis Fibraureae 10 parts, Radix Hyperici Monogyni (Herba Hyperici Monogyni) 12 parts, Caulis Akebiae 15 parts, Herba Zornia Diphyllae 15 parts.
The preparation method of the Chinese medicinal composition capsules agent of above-mentioned treatment conjunctivitis is:
(1) get Herba Lophatheri, put into marmite, add 85 DEG C of boiling water, the amount of boiling water is 12 times of Herba Lophatheri weight, soak 7 minutes, after boiling with high heat, turn slow fire boiling 24 minutes, leach soup, be condensed into the thick paste that relative density is 1.35,60 DEG C of dryings 14 hours, are ground into fine powder, cross 130 mesh sieves;
(2) get Caulis Fibraureae, add the yellow wine of Caulis Fibraureae weight 28%, mix thoroughly, put into and steam container, steam 2.9 hours with big fire, take out, dry, be ground into fine powder, cross 130 mesh sieves;
(3) all the other the 13 taste crude drug except Herba Lophatheri and Caulis Fibraureae are put into 55 DEG C of thermostatic drying chambers, dry 6 hours, take out, grind to the powder altogether, cross 140 mesh sieves;
(4) step (1), step (2) and step (3) gained are mixed, add the amylum pregelatinisatum of step (1), step (2) and step (3) gained gross weight 0.8 times, mixing, be pressed into thin slice, be ground into granule, load No. 1 capsule, every capsules is equipped with granule 0.32g, to obtain final product.
model case three:what XX, man, 56 years old.Main suit: suffer from conjunctivitis more than 3 years.Before 3 years, there is the symptom such as left eye eyelid swelled, the scorching hot swelling pain of eye in patient.Once arrived Duo Jia hospital and carry out diagnosis and treatment, be diagnosed as conjunctivitis, therapeutic effect does not show.On April 15th, 2011 examines.Examine and see patient's left eye eyelid swelled, the scorching hot swelling pain of eye, tear hot gum knot, conjunctival congestion edema, and headache of holding concurrently, nasal obstruction, stool is smooth, oliguria with reddish urine, red tongue, yellow and thin fur, floating and rapid pulse.Be diagnosed as conjunctivitis.Take the Chinese medicinal composition capsules agent of the present embodiment gained treatment conjunctivitis, one day twice, each 2, warm water took.Take 1 week, above-mentioned symptom obviously improves.Continue to take 3 days, all disease knowing disappear.Follow up a case by regular visits to without recurrence.
embodiment 5treat a Chinese medicine composition for conjunctivitis, the primary raw material medicine getting following weight parts is prepared from (every part is 300g): Radix Angelicae Sinensis 15 parts, Radix et Rhizoma Thalictri 12 parts, Flos Eriocauli 11 parts, Herba youngiae japonicae 10 parts, Semen Benincasae 11 parts, Herba Diclipterae Chinensis 13 parts, Spica Prunellae 13 parts, Herba senecionis nemorensis 10 parts, 7.5 parts, Flos Carthami, Herba Polygalae Japonicae 10 parts, Herba Lophatheri 12 parts, Caulis Fibraureae 9 parts, Radix Hyperici Monogyni (Herba Hyperici Monogyni) 11 parts, Caulis Akebiae 14 parts, Herba Zornia Diphyllae 14 parts.
The preparation method of the Chinese medicinal composition granules of above-mentioned treatment conjunctivitis is:
(1) get Herba Lophatheri, put into marmite, add 85 DEG C of boiling water, the amount of boiling water is 12 times of Herba Lophatheri weight, soak 7 minutes, after boiling with high heat, turn slow fire boiling 24 minutes, leach soup, be condensed into the thick paste that relative density is 1.35,60 DEG C of dryings 14 hours, are ground into fine powder, cross 130 mesh sieves;
(2) get Caulis Fibraureae, add the yellow wine of Caulis Fibraureae weight 28%, mix thoroughly, put into and steam container, steam 2.9 hours with big fire, take out, dry, be ground into fine powder, cross 130 mesh sieves;
(3) all the other the 13 taste crude drug except Herba Lophatheri and Caulis Fibraureae are put into 55 DEG C of thermostatic drying chambers, dry 6 hours, take out, grind to the powder altogether, cross 130 mesh sieves;
(4) step (1), step (2) and step (3) gained are mixed, add the amylum pregelatinisatum of step (1), step (2) and step (3) gained gross weight 0.8 times, mixing, is pressed into thin slice, is ground into granule, to obtain final product.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Radix Angelicae Sinensis: base is former: be the dry root of umbelliferae angelica.The property of medicine: sweet, acrid, warm.Return liver, the heart, spleen channel.Function cures mainly: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, traumatic injury, ulcer sores.
Radix et Rhizoma Thalictri: base is former: be the root and rhizome of ranunculaceae plant spun gold Radix et Rhizoma Thalictri, Zhaotong Thalictrum aquilegifolium L. var. sibiricum Regel, plateau Thalictrum aquilegifolium L. var. sibiricum Regel, leafy Thalictrum aquilegifolium L. var. sibiricum Regel, baikal meadowrue root, long column baikal meadowrue root, yellow Thalictrum aquilegifolium L. var. sibiricum Regel, sticky Thalictrum aquilegifolium L. var. sibiricum Regel etc.The property of medicine: bitter in the mouth; Cold in nature.GUIXIN, liver, large intestine channel.Function cures mainly: heat clearing and damp drying, eliminating fire and detoxication.Cure mainly damp-heat dysentery, jaundice, sore swollen toxin, conjunctival congestion and swelling pain, cold, fever, cancerous protuberance.
Flos Eriocauli: have another name called Dai Xingcao, Wen Xingcao, move star grass is the head inflorescence of Eriocaulaceae eriocaulon buergerianum plant Flos Eriocauli band scape.The property of medicine: pungent, sweet, flat.Function cures mainly: find according to modern pharmacological research, this medical instrument has antibacterial, wind and heat eliminating, improving acuity of vision and removing nebula effect, for cataract, and headache, nasal sinusitis, laryngalgia, rubella pruritus etc.
Herba youngiae japonicae: base is former: be root or the herb of feverfew Herba youngiae japonicae.The property of medicine: sweet in the mouth; Micro-hardship; Cool in nature.Function cures mainly: heat-clearing and toxic substances removing, inducing diuresis to remove edema.Main flu, pharyngalgia, eye conjunctivitis, acute mastitis, furuncle toxic swelling, venom, dysentery, cirrhotic ascites, acute nephritis, stranguria with turbid discharge, hematuria, leucorrhea, rheumatic arthritis, traumatic injury.
Semen Benincasae: base is former: be the seed of cucurbitaceous plant Fructus Benincasae.The property of medicine: sweet in the mouth, cold nature.Return lung, large intestine channel.Function cures mainly: removing heat from the lung and dissipating phlegm, eliminating carbuncle evacuation of pus, dampness removing.Main phlegm-heat cough, lung abscess, acute appendicitis, nebulousurine, leukorrhagia, beriberi, edema, stranguria.
Herba Diclipterae Chinensis: base is former: be the herb of acanthaceous plant Herba Diclipterae Chinensis.The property of medicine: sweet in the mouth; Micro-hardship; Cold in nature.GUIXIN, liver, lung meridian.Function cures mainly: heat clearing away, removing heat from blood, dampness removing, removing toxic substances.Main cold, fever, calentura sends out speckle, tells epistaxis, has blood in stool, hematuria, metrorrhagia, cough due to lung-heat, laryngopharynx swelling and pain, liver-heat conjunctival congestion, infantile convulsion, dribbling urination, leukorrhagia, herpes zoster, carbuncle furuncle furuncle, Serpentis lyssodexis.
Spica Prunellae: base is former: be the dry fruit ear of labiate Spica Prunellae.The property of medicine: pungent, bitter, cold.Return liver, gallbladder meridian.Function cures mainly: relieve inflammation or internal heat, improving eyesight, eliminating stagnation, detumescence.For conjunctival congestion and swelling pain, order pearl nyctalgia, has a headache dizzy, scrofula, goiter, and acute mastitis swells and ache, thyromegaly, tuberculous lymphadenitis, cyclomastopathy, hypertension.
Herba senecionis nemorensis: base is former: be the herb of feverfew wood groundsel.The property of medicine: bitter in the mouth; Pungent; Cold in nature.Function cures mainly: heat-clearing and toxic substances removing.Main dysentery, enteritis, hepatitis, conjunctivitis, otitis media, carbuncle treats poison.
Flos Carthami: base is former: be the dried floral of feverfew Flos Carthami.The property of medicine: pungent, temperature.GUIXIN, Liver Channel.Function cures mainly: promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.For amenorrhea, dysmenorrhea, lochia ， mass in the abdomen mass in the abdomen, traumatic injury, skin infection swells and ache.
Herba Polygalae Japonicae: base is former: be herb or the root of milk wort Herba Polygalae Japonicae.Chemical analysis: root is containing triterpenoid saponin, resin, fatty oil, polygalytol.The property of medicine: bitter, micro-pungent, flat.Return lung, stomach, heart channel.Function cures mainly: the hemostasis of expelling phlegm for arresting cough, dissipating blood stasis, mind tranquilizing and the heart calming, removing toxic substances and promoting subsidence of swelling.Main cough with copious phlegm, traumatic injury, rheumatic arthralgia, spit blood, have blood in stool, cardiopalmus, insomnia, laryngopharynx swelling and pain, carbuncle skin infection, venom.
Herba Lophatheri: base is former: be the herb of grass Herba Lophatheri or Chinese Herba Lophatheri.The property of medicine: sweet; Light; Cold.Function cures mainly: heat clearing away; Relieving restlessness; Diuresis.Main dysphoria with smothery sensation is thirsty, aphtha of the mouth and tongue, gingival swelling and pain, children's's night crying due to fright in infant, hot urination, stranguria with turbid discharge.
Caulis Fibraureae: base is former: be rhizome or the leaf of menispermaceous plants Caulis Fibraureae.The property of medicine: bitter, cold in nature.GUIXIN, Liver Channel.Function cures mainly: heat-clearing and toxic substances removing, dampness removing.Main acute tonsillitis, pharyngolaryngitis, upper respiratory tract infection, conjunctivitis, jaundice, gastroenteritis, dysentery, infantile dyspepsia, food poisoning, salpingitis, acute and chronic endometritis, acute pelvic inflammatory disease, vaginitis, furuncle, burn and scald.
Radix Hyperici Monogyni (Herba Hyperici Monogyni): base is former: be the Herb of Garcinia maingayii Radix Hyperici Monogyni (Herba Hyperici Monogyni).The property of medicine: bitter; Cool.GUIXIN, Liver Channel.Function cures mainly: heat-clearing and toxic substances removing, eliminating stasis to stop pain, wind-damp dispelling.Main hepatitis, hepatosplenomegaly, acute pharyngolaryngitis, conjunctivitis, furuncle toxic swelling, Serpentis stings and bee sting, traumatic injury, wind-cold lumbago.
Caulis Akebiae: base is former: be Teng's stem of plants of Lardizabalaceae Caulis Akebiae, threeleaf akebia or Caulis Akebiae.The property of medicine: bitter; Cold in nature.GUIXIN, spleen, kidney, small intestinal, urinary bladder channel.Function cures mainly: clearing away heat and promoting diuresis, blood circulation and channel invigorating.Main red urine, stranguria with turbid discharge, edema, irritable feverish sensation in the chest, larynx larynx pain, aphtha of the mouth and tongue, rheumatic arthralgia, galactostasis, amenorrhea, dysmenorrhea.
Herba Zornia Diphyllae: base is former: be the herb of leguminous plant Herba Zornia Diphyllae.The property of medicine: sweet in the mouth; Cool in nature.Return spleen, Liver Channel.Function cures mainly: clearing away heat and expelling pathogen in the exterior, removing pathogenic heat from blood and toxic substance from the body, dehumidifying diuresis.Main anemopyretic cold, pharyngalgia, conjunctival congestion, acute mastitis, sore swollen toxin, venom, jaundice, has loose bowels, dysentery, infantile malnutrition.
test example 1the clinical practice of the Chinese medicine composition of gained of the present invention treatment conjunctivitis: in October, 2010 in JIUYUE ,-2012, screen 300 routine conjunctivitis patients in 5 hospitals, wherein man 160 example, female 140 example, age 21-66 year, 46.5 years old mean age.Be divided into two groups at random, experimental group and matched group (often organizing 150 people).Experimental group man 80 example, female 70 example, age 21-66 year, 46.5 years old mean age, the course of disease 3 months-3.5 years.Matched group man 80 example, female 70 example, age 21-66 year, 46.5 years old mean age, the course of disease 3 months-3.5 years.Above two groups of patients compare there was no significant difference (P > 0.05) in age, sex, the course of disease, ordinary circumstance etc., and case-data has comparability.
Diagnostic criteria: diagnose according to the dependent diagnostic standard about conjunctivitis in " ophthalmology ".(1) clinical manifestation: ocular pruritis, dry and astringent, eyestrain, with foreign body sensation, chemosis, hemorrhage and many tears etc.(2) lab testing: occur the bacteria infections such as virus or chlamydia in conjunctiva.(3) examination of eyes: conjunctival congestion edema, secretions are mucus, in thinking shape or streak.
Exclusion standard: (1) ocular infection disease is as trachoma.(2) other ocular disease: iritis, glaucoma, uveitis, keratitis, chronic dacryocystitis etc.(3) serious hepatic and kidney function obstacle patient.(4) congenital oculopathy and psychotic.
Therapeutic Method: experimental group takes products obtained therefrom of the present invention, instructions of taking: oral, three times on the one, each 10g, boiled water is taken after mixing it with water, and within 5 days, is 1 course for the treatment of.Matched group uses the medicine (as erythromycin eye ointment, Compound Neomycin Sulfate Eye Drops, ofloxacin eye drops etc.) of conventional therapy conjunctivitis, within 5 days, is 1 course for the treatment of.After two groups of patients all treat 2 courses for the treatment of, carry out Comparison of therapeutic.
Curative effect situation criterion: cure: the clinical manifestations such as eyes are dry and astringent, itch, foreign body sensation disappear, ophthalmic secretions disappears, conjunctiva without hyperemia, lab testing pathogenic bacterium disappear; Take a turn for the better: the Clinical presentation and features such as eyes are dry and astringent, itch, foreign body sensation obviously alleviate, and examination of eyes conjunctival congestion alleviates, and secretions obviously reduces, and lab testing pathogenic bacterium quantity is few; Invalid: clinical symptoms and sign are without significant change, and examination of eyes and lab testing are without change.Total effectively comprising cures and takes a turn for the better.Result is as shown in table 1.
Table 1: the Chinese medicine composition compliance test result of gained treatment conjunctivitis of the present invention
efficacy analysis:as can be seen from Table 1, it is 120 people that the experimental group using gained of the present invention to treat the Chinese medicine composition of conjunctivitis cures number of cases, and only have 3 people invalid, total effective rate reaches 98%; And the healing number of cases of matched group is only 62 people, invalid number of cases is up to 58 people, and total effective rate is only 80%.Test shows, experimental group total effective rate is obviously better than matched group, and its curative effect increases substantially, and cure rate significantly promotes, and inefficiency significantly reduces, and two groups of comparing differences have significance.
The present invention is primary raw material medicine with Radix Angelicae Sinensis, Radix et Rhizoma Thalictri, Flos Eriocauli and Herba youngiae japonicae etc., makes the Chinese medicine composition for the treatment of conjunctivitis.In side, Chinese angelica blood supplementing is invigorated blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.Radix et Rhizoma Thalictri heat clearing and damp drying, eliminating fire and detoxication.Flos Eriocauli has antibacterial, wind and heat eliminating, improving acuity of vision and removing nebula effect.Herba youngiae japonicae heat-clearing and toxic substances removing, inducing diuresis to remove edema.Semen Benincasae removing heat from the lung and dissipating phlegm, eliminating carbuncle evacuation of pus, dampness removing.Herba Diclipterae Chinensis heat clearing away, removing heat from blood, dampness removing, removing toxic substances.Spica Prunellae relieves inflammation or internal heat, improving eyesight, eliminating stagnation, detumescence.Herba senecionis nemorensis heat-clearing and toxic substances removing.Flos Carthami promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.The hemostasis of Herba Polygalae Japonicae expelling phlegm for arresting cough, dissipating blood stasis, mind tranquilizing and the heart calming, removing toxic substances and promoting subsidence of swelling.
Herba Lophatheri heat clearing away; Relieving restlessness; Diuresis.Caulis Fibraureae heat-clearing and toxic substances removing, dampness removing.Radix Hyperici Monogyni (Herba Hyperici Monogyni) heat-clearing and toxic substances removing, eliminating stasis to stop pain, wind-damp dispelling.
Caulis Akebiae clearing away heat and promoting diuresis, blood circulation and channel invigorating.Herba Zornia Diphyllae clearing away heat and expelling pathogen in the exterior, removing pathogenic heat from blood and toxic substance from the body, dehumidifying diuresis.Many medicines share, and mutually coordinate, play wind and heat eliminating altogether, improving eyesight is relieved inflammation or internal heat, effect of clearing away heat and expelling pathogen in the exterior, eliminating stasis to stop pain, eliminating fire and detoxication, improving acuity of vision and removing nebula, fundamentally can eliminate sufferer, not easily recur.
Finally it should be noted that, embodiment is the detailed description of the invention of optimum of the present invention, be not limited to the present invention, although with reference to previous embodiment to invention has been detailed description, for a person skilled in the art, it still can be modified to the technical scheme described in foregoing embodiments, or carries out equivalent replacement to wherein portion of techniques feature.Within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (10)
1. treat a Chinese medicine composition for conjunctivitis, it is characterized in that, take off the primary raw material medicine stating weight proportion and be prepared from: Radix Angelicae Sinensis 12-18, Radix et Rhizoma Thalictri 10-15, Flos Eriocauli 8-13, Herba youngiae japonicae 6-12, Semen Benincasae 9-14, Herba Diclipterae Chinensis 11-16, Spica Prunellae 10-17, Herba senecionis nemorensis 7-13, Flos Carthami 6-9, Herba Polygalae Japonicae 8-12, Herba Lophatheri 10-14, Caulis Fibraureae 7-12, Radix Hyperici Monogyni (Herba Hyperici Monogyni) 9-13, Caulis Akebiae 10-16, Herba Zornia Diphyllae 12-16.
2. the Chinese medicine composition for the treatment of conjunctivitis as claimed in claim 1, is characterized in that, take off the primary raw material medicine stating weight proportion and be prepared from: Radix Angelicae Sinensis 14-16, Radix et Rhizoma Thalictri 11-14, Flos Eriocauli 9-12, Herba youngiae japonicae 8-11, Semen Benincasae 10-12, Herba Diclipterae Chinensis 12-14, Spica Prunellae 12-14, Herba senecionis nemorensis 9-11, Flos Carthami 7-8, Herba Polygalae Japonicae 9-11, Herba Lophatheri 11-13, Caulis Fibraureae 8-10, Radix Hyperici Monogyni (Herba Hyperici Monogyni) 10-12, Caulis Akebiae 13-15, Herba Zornia Diphyllae 13-15.
3. the Chinese medicine composition for the treatment of conjunctivitis as claimed in claim 1, is characterized in that, take off the primary raw material medicine stating weight proportion and be prepared from: Radix Angelicae Sinensis 15, Radix et Rhizoma Thalictri 12, Flos Eriocauli 11, Herba youngiae japonicae 10, Semen Benincasae 11, Herba Diclipterae Chinensis 13, Spica Prunellae 13, Herba senecionis nemorensis 10, Flos Carthami 7.5, Herba Polygalae Japonicae 10, Herba Lophatheri 12, Caulis Fibraureae 9, Radix Hyperici Monogyni (Herba Hyperici Monogyni) 11, Caulis Akebiae 14, Herba Zornia Diphyllae 14.
4. the Chinese medicine composition of the treatment conjunctivitis as described in as arbitrary in claims 1 to 3, it is characterized in that, the Chinese medicine composition of this treatment conjunctivitis is made pharmaceutically acceptable granule, and the preparation method of described granule is:
(1) Herba Lophatheri is got, put into marmite, add 80-90 DEG C of boiling water, the amount of boiling water is 8-15 times of Herba Lophatheri weight, soak 5-10 minute, after boiling with high heat, turn slow fire boiling 18-26 minute (preferably turning slow fire boiling 24 minutes), leach soup, be condensed into the thick paste (being preferably condensed into the thick paste that relative density is 1.35) that relative density is 1.33-1.36,60 DEG C of dryings 14 hours, are ground into fine powder, cross 130 mesh sieves;
(2) get Caulis Fibraureae, add the yellow wine (preferably adding the yellow wine of Caulis Fibraureae weight 28%) of Caulis Fibraureae weight 25%-32%, mix thoroughly, put into and steam container, steam 2.2-3.5 hour (preferably steaming 2.9 hours with big fire) with big fire, take out, dry, be ground into fine powder, cross 130 mesh sieves;
(3) all the other the 13 taste crude drug except Herba Lophatheri and Caulis Fibraureae are put into 55 DEG C of thermostatic drying chambers, dry 4-8 hour (preferably dry 6 hours), take out, grind to the powder altogether, cross 130 mesh sieves;
(4) step (1), step (2) and step (3) gained are mixed, add step (1), step (2) and step (3) gained gross weight 0.6-1 amylum pregelatinisatum (preferably adding the amylum pregelatinisatum of step (1), step (2) and step (3) gained gross weight 0.8 times) doubly, mixing, be pressed into thin slice, be ground into granule, obtain final product.
5. the Chinese medicine composition of the treatment conjunctivitis as described in as arbitrary in claims 1 to 3, it is characterized in that, the Chinese medicine composition of this treatment conjunctivitis is made pharmaceutically acceptable pill, and the preparation method of described pill is:
(1) Herba Lophatheri is got, put into marmite, add 80-90 DEG C of boiling water (preferably adding 85 DEG C of boiling water), the amount of boiling water is 8-11 times (amount of preferred boiling water is 9 times of Herba Lophatheri weight) of Herba Lophatheri weight, soak 3-8 minute (preferably soaking 5 minutes), after boiling with high heat, turn slow fire boiling 15-25 minute (preferably turning slow fire boiling 20 minutes), leach soup;
(2) get Caulis Fibraureae, add the yellow wine (preferably adding the yellow wine of Caulis Fibraureae weight 28%) of Caulis Fibraureae weight 25%-32%, mix thoroughly, put into and steam container, steam 2.2-3.5 hour (preferably steaming 2.9 hours with big fire) with big fire, take out, dry, be ground into fine powder, cross 150 mesh sieves;
(3) all the other the 13 taste crude drug except Herba Lophatheri and Caulis Fibraureae are put into 55 DEG C of thermostatic drying chambers, dry 4-8 hour (preferably dry 6 hours), take out, grind to the powder altogether, cross 150 mesh sieves;
(4) by step (2) and the mixing of step (3) gained, with the general ball of step (1) gained, 45 DEG C of dryings 10 hours, the heavy 0.2g of every ball, to obtain final product.
6. the Chinese medicine composition of the treatment conjunctivitis as described in as arbitrary in claims 1 to 3, it is characterized in that, the Chinese medicine composition of this treatment conjunctivitis is made pharmaceutically acceptable tablet, and the preparation method of described tablet is:
(1) Herba Lophatheri is got, put into marmite, add 80-90 DEG C of boiling water (preferably adding 85 DEG C of boiling water), the amount of boiling water is 8-15 times (amount of preferred boiling water is 12 times of Herba Lophatheri weight) of Herba Lophatheri weight, soak 5-10 minute (preferably soaking 7 minutes), after boiling with high heat, turn slow fire boiling 18-26 minute (preferably turning slow fire boiling 24 minutes), leach soup, be condensed into the thick paste (being preferably condensed into the thick paste that relative density is 1.35) that relative density is 1.33-1.36,60 DEG C of dryings 14 hours, are ground into fine powder, cross 130 mesh sieves;
(2) get Caulis Fibraureae, add the yellow wine (preferably adding the yellow wine of Caulis Fibraureae weight 28%) of Caulis Fibraureae weight 25%-32%, mix thoroughly, put into and steam container, steam 2.2-3.5 hour (preferably steaming 2.9 hours with big fire) with big fire, take out, dry, be ground into fine powder, cross 130 mesh sieves;
(3) all the other the 13 taste crude drug except Herba Lophatheri and Caulis Fibraureae are put into 55 DEG C of thermostatic drying chambers, dry 4-8 hour (preferably dry 6 hours), take out, grind to the powder altogether, cross 130 mesh sieves;
(4) step (1), step (2) and step (3) gained are mixed, add step (1), step (2) and step (3) gained gross weight 0.6-1 amylum pregelatinisatum (preferably adding the amylum pregelatinisatum of step (1), step (2) and step (3) gained gross weight 0.8 times) doubly, mixing, be pressed into thin slice, be ground into granule, tabletting, the heavy 0.4g of every sheet, to obtain final product.
7. the Chinese medicine composition of the treatment conjunctivitis as described in as arbitrary in claims 1 to 3, it is characterized in that, the Chinese medicine composition of this treatment conjunctivitis is made pharmaceutically acceptable capsule, and the preparation method of described capsule is:
(1) Herba Lophatheri is got, put into marmite, add 80-90 DEG C of boiling water (preferably adding 85 DEG C of boiling water), the amount of boiling water is 8-15 times (amount of preferred boiling water is 12 times of Herba Lophatheri weight) of Herba Lophatheri weight, soak 5-10 minute (preferably soaking 7 minutes), after boiling with high heat, turn slow fire boiling 18-26 minute (preferably turning slow fire boiling 24 minutes), leach soup, be condensed into the thick paste (being preferably condensed into the thick paste that relative density is 1.35) that relative density is 1.33-1.36,60 DEG C of dryings 14 hours, are ground into fine powder, cross 130 mesh sieves;
(2) get Caulis Fibraureae, add the yellow wine (preferably adding the yellow wine of Caulis Fibraureae weight 28%) of Caulis Fibraureae weight 25%-32%, mix thoroughly, put into and steam container, steam 2.2-3.5 hour (preferably steaming 2.9 hours with big fire) with big fire, take out, dry, be ground into fine powder, cross 130 mesh sieves;
(3) all the other the 13 taste crude drug except Herba Lophatheri and Caulis Fibraureae are put into 55 DEG C of thermostatic drying chambers, dry 4-8 hour (preferably dry 6 hours), take out, grind to the powder altogether, cross 140 mesh sieves;
(4) step (1), step (2) and step (3) gained are mixed, add step (1), step (2) and step (3) gained gross weight 0.6-1 amylum pregelatinisatum (preferably adding the amylum pregelatinisatum of step (1), step (2) and step (3) gained gross weight 0.8 times) doubly, mixing, be pressed into thin slice, be ground into granule, load No. 1 capsule, every capsules is equipped with granule 0.32g, to obtain final product.
8. the preparation method of the Chinese medicinal composition granules for the treatment of conjunctivitis as claimed in claim 4, is characterized in that, add 85 DEG C of boiling water in step (1).
9. the preparation method of the Chinese medicinal composition granules for the treatment of conjunctivitis as claimed in claim 4, is characterized in that, in step (1), the amount of boiling water is 12 times of Herba Lophatheri weight.
10. the preparation method of the Chinese medicinal composition granules for the treatment of conjunctivitis as claimed in claim 4, is characterized in that, soak 7 minutes in step (1).
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Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101129588A (en) * | 2007-08-20 | 2008-02-27 | 陈江 | Instant powder for conjunctivitis |
| CN101450155A (en) * | 2007-12-03 | 2009-06-10 | 陈海生 | Chinese herbal medicine for treating eyes disease |
| CN103721000A (en) * | 2013-10-24 | 2014-04-16 | 青岛华仁技术孵化器有限公司 | Medicinal preparation for treating epidemic keratoconjunctivitis |
| CN103893502A (en) * | 2014-03-02 | 2014-07-02 | 王树军 | Traditional Chinese medicine for treating phlyctenular conjunctivitis |
| CN104055960A (en) * | 2014-07-16 | 2014-09-24 | 天津朝花夕拾科技有限公司 | Traditional Chinese medicine for treating red eye sore pain |
| CN104491562A (en) * | 2015-01-16 | 2015-04-08 | 银哲 | Traditional Chinese medicine composition used for treating conjunctivitis |
-
2015
- 2015-06-18 CN CN201510339089.9A patent/CN104922518A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101129588A (en) * | 2007-08-20 | 2008-02-27 | 陈江 | Instant powder for conjunctivitis |
| CN101450155A (en) * | 2007-12-03 | 2009-06-10 | 陈海生 | Chinese herbal medicine for treating eyes disease |
| CN103721000A (en) * | 2013-10-24 | 2014-04-16 | 青岛华仁技术孵化器有限公司 | Medicinal preparation for treating epidemic keratoconjunctivitis |
| CN103893502A (en) * | 2014-03-02 | 2014-07-02 | 王树军 | Traditional Chinese medicine for treating phlyctenular conjunctivitis |
| CN104055960A (en) * | 2014-07-16 | 2014-09-24 | 天津朝花夕拾科技有限公司 | Traditional Chinese medicine for treating red eye sore pain |
| CN104491562A (en) * | 2015-01-16 | 2015-04-08 | 银哲 | Traditional Chinese medicine composition used for treating conjunctivitis |
Non-Patent Citations (1)
| Title |
|---|
| 李昌德: ""五花五草汤治疗流行性结膜炎46例"", 《中国中医急症》 * |
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