CN103520552A - Traditional Chinese medicine composition for treating acute conjunctivitis and preparation method thereof - Google Patents

Abstract

The invention discloses a traditional Chinese medicine composition for treating acute conjunctivitis. The various raw materials in the traditional Chinese medicine composition are: honeysuckle, forsythia, mulberry leaves, isatidis, Prunella vulgaris, Fangfeng, nepeta, guanzhong, and arctium , reed root, dandelion, baicalin, notopterygium, chuanxiong, angelica, habitat, gentian, red peony, wild chrysanthemum, cicada slough, white fresh skin, licorice, Kochia chinensis, Budisma, green scorpion, big green salt, White oak, half-pinner, calamine, bone grass. The present invention has the advantages of mainly expelling wind and dispelling pathogenic factors, clearing away heat and detoxifying. For those who are seriously ill and affect the wind wheel, it is mainly used to clear away heat and detoxify, clear liver, improve eyesight and relieve clouding; and the production process is simple, the toxic side effects are small, the administration is convenient, the medicine is easy to manufacture, and the cost is low. It can directly reach the lesion, the healing time is short, and it is not easy to relapse after curing.

Description

A kind of traditional Chinese medicine composition for treating acute conjunctivitis and preparation method thereof

the

technical field

The invention relates to a medical preparation containing raw materials derived from plants, animals or minerals, in particular to a traditional Chinese medicine composition for treating acute conjunctivitis and a preparation method thereof.

the

Background technique

Epidemic hemorrhagic conjunctivitis is an outbreak of severe acute conjunctivitis, commonly known as "red eye", which mostly occurs in summer and autumn, and its causative pathogen is enterovirus 70. Severe pain, photophobia, tearing and other severe irritation symptoms and watery discharge; eyelid redness, conjunctival hyperemia, edema, subconjunctival point, sheet or extensive hemorrhage; corneal diffuse punctate epithelial shedding, fluorescein staining, Swollen preauricular or submandibular lymph nodes. The disease is characterized by acute onset, strong infectivity, severe irritation symptoms, high conjunctival hyperemia, edema, subconjunctival hemorrhage, corneal damage, and preauricular lymph gland enlargement.

Acute conjunctivitis is also known as Tianxing red eye in traditional Chinese medicine. Refers to the outbreak of redness and swelling of the eyelids and white eyes, alternating pain and itching, sticky gums and tears, and cloudy eyes. See "The Essence of the Silver Sea". Also known as Tianxing red fever, Tianxing violent red, Zhu Yanmengxu. Also known as pink eye. This disease is mostly caused by wind-heat toxin and pathogenic wind, which is equivalent to today's acute infectious conjunctivitis. Easy to cause widespread popularity. Therefore, the primary prevention of this disease. Items used by patients must be isolated and disinfected. Internal treatment should clear away heat and disperse pathogenic factors, cool blood and detoxify. There are many names of the disease of Tianxing red eye. "Shi Yi De Xiao Fang" in the Yuan Dynasty called "Tianxing Chimu", and Ming Dynasty's "Scrutiny of Yao Han" called "Tianxing Red Fever". It is believed that one person with red eyes in Tianxing gets sick and spreads to the whole family, which is a disease caused by miasma. It can be cured within a week. If the course of the disease lasts for a long time, it can often cause black eyes and cloudy eyes. Red eyes in the sky are mostly caused by wind-heat toxins invading the eyes; or due to heat accumulation in the lungs and stomach, internal and external evils attack the eyes. Itchy eyes at the beginning, gradually suffering from sandy eyes, burning pain and photophobia, eyelids that cannot be opened, tears pouring out like soup, sticky eyelashes, white eyes with red veins, severe cases, white eyes and inner surface of the eyelids. Symptoms such as hemorrhage in shape or flakes, redness and swelling of the eyelids, swelling and pain in front of the ears, or combined with chills, fever, nasal congestion, runny nose, and general discomfort. "Yinhai Jingwei" and "Mujing Dacheng" and other ancient books on ophthalmology also have a lot of discussion on eye itching. Evil attack and full of itching belong to deficiency, and deficiency causes itching. "Mujing Dacheng·Muitch" thinks: what is the cause of pruritus, fire, wind, and blood loss. In short, traditional Chinese medicine believes that its etiology and pathogenesis are nothing more than wind, heat, Dampness, deficiency, lung meridian evil, liver and gallbladder wind-heat, causing wind-heat to attack the eyes; weakness of the spleen and stomach, dampness stagnation, stagnation and heat transformation, damp-heat accumulation and stagnation of white clear; liver blood deficiency, blood deficiency generates wind, and deficiency wind invades the eyes. Clinical diagnosis: the onset of pink eye disease is acute, usually within 1-2 days of infection with bacteria, and most of the symptoms are in both eyes. It is highly contagious, and the disease can be reinfected due to low immunity after recovery (if you contact the patient again, you can still get the disease) , From babies of a few months to the elderly in their 80s and 90s. The epidemic is fast. After suffering from pink eye, one person often gets the disease, causing widespread transmission in the whole family, kindergartens, schools, factories, etc. within 1-2 weeks. Male, female, old and young, a large number of patients are infected. Pink eye disease usually occurs in both eyes successively. In the early stage of the disease, patients feel hot, burning, photophobia, and red eyes in both eyes. Redness, excess eye gum, photophobia, tearing. When getting up in the morning, the eyelids are often stuck by secretions and are difficult to open. Some patients have small bleeding spots or spots on the conjunctiva, and the secretions are mucopurulent. A layer of gray-white pseudomembrane is formed on the surface of the conjunctiva, and there may be gray-white infiltration points on the edge of the cornea. In severe cases, it may be accompanied by systemic symptoms such as headache, fever, fatigue, and swollen preauricular lymph nodes.

Modern medicine believes that the common pathogenic bacteria are Diplococcus pneumoniae Kochweeks bacillus, influenza bacillus, Staphylococcus aureus and Streptococcus can also be seen. The latter two bacteria can usually parasitize in the conjunctival sac and do not cause conjunctivitis, but Acute conjunctivitis can sometimes occur when other conjunctival lesions and local or systemic resistance are reduced. Bacteria can directly contact the conjunctiva through a variety of media, and spread rapidly in public places, collective units such as kindergartens, schools and families, leading to epidemics. Especially in spring and autumn, various respiratory diseases such as influenza and rhinitis are prevalent, and conjunctivitis pathogenic bacteria may spread through respiratory secretions.

In terms of treatment, after getting pink eye disease, it is necessary to actively treat it. Generally, it is required to be timely, thorough and persistent. Once found, treat immediately without interruption. At the beginning, the eyelids and conjunctiva are swollen, and cold compresses can be used, 3 times a day, 20 minutes each time. When one eye suffers from red eye and the other two eyes are not infected, the healthy eye should also be prevented from being infected. When washing or instilling eye drops, the head should be turned to the affected side, and the head should be turned to the affected side when sleeping to prevent secretions from flowing into the healthy eye. Eye. After the symptoms disappear completely, the treatment should be continued for 1 week to prevent recurrence. Treatment can be done by flushing the eyes. When there is a lot of secretions in the affected eye, it is advisable to flush the conjunctival sac with an appropriate flushing agent such as normal saline or 2% boric acid water, 2-3 times a day, and wipe the eyelid margin with a sterile cotton swab. Eye drops or ointment can also be applied to the affected eye. If it is a bacterial infection, the most effective antibiotic eye drops can be selected according to the detected bacteria. According to the severity of the disease, eye drops are given once every 2-3 hours or every hour. The commonly used eye drops contain 10%-20% sulfa Acetyl sodium, 0.3% norfloxacin, 0.25% chloramphenicol eye drops, etc., you can apply antibiotic eye ointment before going to bed at night, such as ciprofloxacin, aureomycin or tetracycline eye ointment, and secrete it before each application. Scrub and clean the objects to improve the curative effect. For conjunctivitis with mixed virus infection, in addition to the above drugs, antiviral eye drops can also be used. For adenovirus, 0.1% oxybenzazole eye drops and 0.1% peptide butylamine emulsion can be used. For small viruses, 0.1% herpes eye drops can be used. Net, 0.1% acyclovir eye drops, etc., 2-3 times a day, and interferon can also be used if necessary. Bacterial culture can be carried out when conditions permit, and drug susceptibility tests can be performed to select appropriate antibiotics.

the

Contents of the invention

The technical problem to be solved by the present invention is to provide a new drug with simple formula, simple manufacturing process, less toxic and side effects, convenient administration, easy manufacture of medicament, and low cost. The present invention is a traditional Chinese medicine composition, but the traditional Chinese medicine with mild smell is selected. The invention adopts traditional Chinese medicinal materials with different medicinal properties, carries out scientific compatibility, can achieve an ideal therapeutic effect, is safe, has little toxic and side effects, is simple to prepare, can directly reach the lesion, has short healing time, and is not easy to relapse after being cured.

In order to solve the above-mentioned technical problems, the present invention provides a Chinese medicine composition for treating acute conjunctivitis, wherein the weight-to-number ratios of various raw materials in the Chinese medicine composition are: 10-25 parts of honeysuckle, 10-25 parts of forsythia, 10-25 parts of mulberry leaves, 10-25 parts of Radix Isatidis, 10-25 parts of Prunella vulgaris, 10-25 parts of Fangfeng, 10-20 parts of Nepeta, 10-20 parts of Rhizome, 10-20 parts of Arctium, 10 parts of Reed Root ～20 parts, dandelion 10～25 parts, skullcap 10～20 parts, notopterygium 10～20 parts, chuanxiong 10～25 parts, angelica 10～25 parts, raw land 10～25 parts, gentian 10～25 parts, red peony root 10-25 parts, 10-25 parts of wild chrysanthemum, 10-25 parts of cicada slough, 10-20 parts of white fresh skin, 10-20 parts of licorice, 10-20 parts of Kochia chinensis, 10-25 parts of Budisma jasmine 10-20 parts of fenugreek, 10-25 parts of Daqing salt, 10-20 parts of white oak, 10-20 parts of half-side flag, 10-25 parts of calamine and 10-20 parts of chicken bone grass.

In the traditional Chinese medicine composition for treating acute conjunctivitis, the weight-to-number ratio of various raw materials can also be: 10-15 parts of honeysuckle, 20-25 parts of forsythia, 10-25 parts of mulberry leaves, 15-25 parts of Radix Radix, 20-25 parts of Prunella vulgaris, 10-20 parts of Fangfeng, 10-15 parts of Nepeta, 10-20 parts of Rhizome, 10-20 parts of Burdock, 10-20 parts of Reed Root, 10-15 parts of Dandelion, 10-20 parts of Scutellaria baicalensis 15 parts, notopterygium 15-20 parts, chuanxiong 20-25 parts, angelica 20-25 parts, habitat 10-15 parts, gentian 10-25 parts, red peony 10-25 parts, wild chrysanthemum 10-20 parts, cicada slough 10-15 parts, 10-15 parts of white fresh skin, 15-20 parts of licorice, 10-15 parts of Kochia scoparia, 20-25 parts of Budisma japonica, 10-15 parts of Qingzizi, 10-20 parts of Daqing salt , 10-15 parts of white oak, 15-20 parts of half-pinner, 10-25 parts of calamine and 15-20 parts of chicken bone grass.

The traditional Chinese medicine composition for treating acute conjunctivitis, the weight-to-number ratio of various raw materials can also be: 10-25 parts of honeysuckle, 10-20 parts of forsythia, 10-20 parts of mulberry leaves, 10-20 parts of Radix Radix, 10-20 parts of Prunella vulgaris, 10-25 parts of Fangfeng, 10-20 parts of Nepeta, 15-20 parts of Rhizome, 10-15 parts of Arctium, 15-20 parts of Reed Root, 10-20 parts of Dandelion, 10-20 parts of Scutellaria baicalensis 20 parts, notopterygium 10-20 parts, Chuanxiong 10-25 parts, angelica 10-25 parts, habitat 10-25 parts, gentian 10-20 parts, red peony 10-20 parts, wild chrysanthemum 10-25 parts, cicada slough 10 to 25 parts, 10 to 20 parts of white fresh skin, 10 to 20 parts of licorice, 10 to 20 parts of Kochia scoparia, 10 to 25 parts of Mimenghua, 10 to 20 parts of Qingshenzi, 10 to 25 parts of Daqing salt , 10-20 parts of white oak, 10-20 parts of half-pinner, 10-20 parts of calamine and 10-20 parts of chicken bone grass.

In order to solve the above-mentioned technical problems, the present invention also provides a preparation method of a Chinese medicine composition for the treatment of acute conjunctivitis, the dosage form of the Chinese medicine composition is a tablet, and the preparation method comprises:

a. Put honeysuckle, forsythia and mulberry leaves into 60%-90% ethanol and heat and reflux for extraction to obtain extract 1;

b. Take the rest of the remaining raw materials, add water and heat under reflux for extraction, and obtain the extract 2;

c. Combine the extract 1 and the extract 2, recover the ethanol under reduced pressure, concentrate and suction, filter and absorb to obtain the raw drug solution; add dextrin or starch for tableting.

In the step a, put honeysuckle, forsythia and mulberry leaves into 10 times the amount of ethanol, heat and reflux for extraction twice, each time for 1 to 2 hours;

In the step b, put the rest of the raw materials into 10 times the amount of water, heat and reflux extraction for 3 times, each time for 30 minutes to 1 hour.

In the step c, the extract 1 and the extract 2 are combined, the ethanol is recovered under reduced pressure and concentrated to a concentration of 0.5g crude drug/mL, after suction filtration, the relative density of the filtrate is about 1.08 at 20°C; the above filtrate Through a macroporous adsorption resin column with a volume of 10 L, first elute with deionized water or distilled water 10 times the volume of the resin column, and then eluted with 95% ethanol 5 times the volume of the resin column, collect the ethanol eluate, remove the solvent, Obtain the raw material liquid; add starch or dextrin and press into tablets. the

In order to solve the above-mentioned technical problems, the present invention also provides a preparation method of a Chinese medicine composition for treating acute conjunctivitis, the dosage form of the Chinese medicine composition is eye drops, and the preparation steps are:

a. Take the crude drug and add water to extract twice, concentrate and filter the extract to obtain extract 1, and the dregs for subsequent use;

b. Soak the medicinal dregs in step a with 60-90% ethanol for 1 hour, extract twice, each time for 2 hours, combine the extracts, filter at 80-160 mesh, centrifuge at 6000-10000 rpm, and take the above The clear liquid is ultrafiltered through an ultrafiltration column with a cut-off molecular weight of 5000-10000, and the ultrafiltrate is concentrated under reduced pressure to an extract 2 with a relative density of 1.35 at 80°C;

c. Mix extract 1 and extract 2, add 0.05% sodium chloride and 80-100 times distilled water of the total mass of the mixed extract, and add a 5% sodium hydroxide solution to adjust the pH to 6.5-7.5, Then add 0.2% activated carbon and boil for 10 minutes, filter, subpackage, and sterilize to obtain eye drops.

In order to solve the above technical problems, the present invention further provides a dosage form of a traditional Chinese medicine composition for treating acute conjunctivitis, said dosage form is: tablet, sugar-coated tablet, film-coated tablet, enteric-coated tablet, capsule, hard Capsules, soft capsules, oral liquids, buccal preparations, granules, granules, honeyed pills, powders, elixirs, solutions, injections, suppositories, plasters, syrups, powders or patches.

The traditional Chinese medicine composition, when the medicine is in use, is taken as a decoction, 1 dose per day, decocted in water and taken twice, every 7 days is a course of treatment; when the Chinese medicine composition is used in pills, capsules or tablets, Three times a day, every 7 days as a course of treatment.

The traditional Chinese medicine composition of the present invention mainly has the functions of expelling wind and dispelling pathogenic factors, clearing away heat and detoxification. For those who are seriously ill and affect the wind wheel, it is mainly used to clear away heat and detoxify, clear liver, improve eyesight and relieve clouding; and the production process is simple, the toxic side effects are small, the administration is convenient, the medicine is easy to manufacture, and the cost is low. The invention adopts traditional Chinese medicinal materials with different medicinal properties, carries out scientific compatibility, can achieve an ideal therapeutic effect, is safe, has little toxic and side effects, is simple to prepare, can directly reach the lesion, has short healing time, and is not easy to relapse after being cured.

the

Detailed ways

Viral conjunctivitis belongs to the category of "Tianxing red eyes" and "Tianxing red eyes and cloudy eyes" in traditional Chinese medicine. Traditional Chinese medicine believes that the disease is caused by a sudden infection of qi and the attack of wind-heat evil poison. "Internal Classics" pointed out: "It is in the skin, and it is sweated." "Treatise on Febrile Diseases" pointed out: "If the pulse is floating, the disease is on the surface, and you can sweat, Mahuang Decoction." It reveals that the syndrome of wind-heat can be treated by divergent methods. As the "Yinhai Guide" said, "the heat of fire is evil, and it is advisable to cause it if you are afraid of its fall." "Danxi Xinfa" pointed out: "For those with strong wind and fire, do not use cold medicine suddenly, and must also warm and disperse." "Jingyue Quanshu Chuanzhonglu" holds that: "The fire caused by exogenous factors should be cured first, and the wind will disperse and the fire will stop itself." "Suwen Liuyuan Zhengji Dalun" pointed out: "The fire is stagnant." Therefore, in the treatment of viral conjunctivitis, it is advisable to use the method of dispersing heat and clearing away heat simultaneously, that is, if there is cold and cool in evacuation, the pungent and warm will not cause excessive fire; Traditional Chinese medicine believes that this disease is mostly caused by the qi of exogenous infection, or the accumulation of heat in the lungs and stomach, and the combination of internal and external evils attacking the eyes. Because the pestilential air invades the eyes, the white eyes are located in the outer layer of the eye pearl and bear the brunt of it, so the white eyes are red and red, the sand is astringent and hot, the eyes are ashamed and shed tears, and the eyes are more clear and dilute. Epidemic Qi is mostly heat-toxin in nature. If there is accumulated heat in the lungs and stomach, it can be seen to suffer from heat and pain in the eyes, headache, dry throat, thirst, red urine and stool, red tongue, yellow fur, etc. Excessive internal heat. In severe cases, the wind wheel may be invaded, and black eyes and stars may develop.

In the prescription, mulberry leaves, burdock seeds, nepeta, and Fangfeng are used to dispel wind and evil, honeysuckle, forsythia, isatidis, etc. to clear away heat and detoxify, and Prunella vulgaris, Guanzhong, and reed root are used to clear away heat. In severe cases, dandelion, gentian, and scutellaria baicalensis are used to clear away heat and detoxify, Mimeng flower, green chrysanthemum, wild chrysanthemum, etc. can improve eyesight and relieve cloudy eyes, clear liver and relieve fire, and licorice to reconcile various medicines, and play together to dispel wind and pathogens, clear away heat and detoxify To achieve the purpose of expelling pathogenic factors and curing diseases. Modern pharmacological studies have confirmed that honeysuckle, forsythia, scutellaria baicalensis, isatis root, dandelion, wild chrysanthemum, windproof, etc. in the prescription, most of which have anti-inflammatory, antibacterial, and antiviral effects. Therefore, in the treatment of this disease, on the basis of unification with syndrome differentiation, these drugs are purposefully used for prescription dispensing, which further strengthens the pertinence of treatment. Kochia chinensis clears heat and promotes dampness, dispels wind and relieves itching, notopterygium dispels wind and relieves itching, is accompanied by cicada slough to dispel wind, Chuanxiong, angelica, and rhizoma rhizome nourishes blood and dispels wind, which means "to treat wind first, treat blood, blood circulates wind to extinguish itself". Modern pharmacological studies have shown that cicada slough has anti-inflammatory and anti-allergic effects. Calamine can detoxify, improve eyesight, reduce cloudiness, absorb dampness and relieve itching. Modern research shows that it has the functions of cooling and relieving itching, anti-inflammation and detumescence, and can absorb the acid secretion of wound surface, remove rot, lift pus and promote muscle growth. Daqing salt clears heat and cools blood, improves eyesight and moisturizes dryness. "Shen Nong's Materia Medica" contains: "mainly improves eyesight, relieves eye pain, nourishes qi, strengthens muscles and bones" chicken bone grass clears heat. White oak, mainly for malnutrition in children, hernia in adults, and acute conjunctivitis. Banner Banner, clearing heat and detoxification, reducing swelling and relieving pain. Licorice harmonizes various medicines. In the treatment, it is mainly based on dispelling wind and pathogenic factors, clearing away heat and detoxification. For those who are seriously ill and affect the wind wheel, clear away heat and detoxify, clear liver, improve eyesight and relieve nebula.

Honeysuckle, heat-clearing and detoxifying, "Compendium of Materia Medica" contains "Honeysuckle is good at detoxifying, so it controls carbuncle, swollen toxin, sore and ringworm...". Since ancient times, honeysuckle is often used to clear away heat and detoxify, treat febrile disease fever, heat-toxin bloody dysentery, carbuncle and other diseases. Modern pharmacological studies have shown that honeysuckle has antibacterial, antiviral, anti-inflammatory, antipyretic, and immune-regulating functions. Traditional Chinese medicine believes that honeysuckle is cold in nature, sweet in taste, and calm in air. boils and other diseases. And it has the function of spreading and dispelling. Honeysuckle has a strong heat-clearing and detoxifying effect, and is commonly used in surgery.

Forsythia, bitter, slightly cold. Return lung, heart, gallbladder channel. Forsythia has a broad-spectrum antibacterial effect, has a strong inhibitory effect on Staphylococcus aureus and Shigella shigellii, and has a certain inhibitory effect on other pathogenic bacteria, influenza virus, and fungi. Has anti-inflammatory effect. The oleanolic acid contained in this product has the effects of strengthening the heart, diuresis and lowering blood pressure. Vitamin P can reduce the permeability and fragility of blood vessels and prevent hemolysis. The decoction has anti-emetic effect and anti-liver damage effect. Heat-clearing and toxic substances removing, reducing swelling and dissipating stagnation, dispelling wind-heat. Indications for carbuncle and sore, phlegm nucleus scrofula, exogenous wind-heat, febrile disease at the onset, hot stranguria, astringent pain, etc. ① "Herbal Classic": main cold and heat, rat flaccidity, scrofula, carbuncle and malignant sore, goiter, knot heat. ② "Bie Lu": remove white worms. ③ "On the Properties of Medicine": It is mainly beneficial to the five stranguria, obstructed urination, and removes heat from the heart. ④ "Rihuazi Materia Medica": clears the small intestine, drains pus. Treat sores and furuncles, relieve pain, and improve menstruation. 5. Li Gao: dissipate the accumulation of menstrual blood and qi; detumescence. ⑥Wang Haogu: Cure deafness and turbidity.

Mulberry leaves, dispelling wind-heat, clearing lung and moistening dryness, calming liver and improving eyesight, cooling blood to stop bleeding. , Indications for wind-heat cold or the beginning of wind-temperature, fever and headache, sweating and aversion to wind, cough and chest pain; or dry cough without phlegm; dry throat and thirst; wind-heat and disturbance of liver yang; red eyes, swelling and pain. For anemopyretic cold, dry cough due to lung heat, dizziness and headache, conjunctival congestion and blurred vision. ① "The Classic": In addition to cold and heat, sweating. ② "Tang Materia Medica": decoct in water to get thick juice, remove beriberi and edema, and benefit the large and small intestine. ③ "Shandong Traditional Chinese Medicine": treat sore throat, gingival swelling and pain, head and face edema. ④ "Supplements to Materia Medica": The main cholera abdominal pain is vomited, and the dried one is boiled and taken in Dongyue. Finely file, decoct brown sugar in a large cauldron to remove old wind and persistent blood. ⑤ "Rihuazi Materia Medica": sharpen the five internal organs, clear the joints, lower the qi, decoct and take; remove wind pain and sweating, and beat blood stasis, and steam it; snakes, insects and centipedes bite, apply salt. 6. "Ben Cao Tu Jing": Boil soup and drench the hands and feet to remove wind numbness. ⑦ "Danxi Heart Method": Drying is the end, and the hollow rice is drunk and taken wither to stop night sweats.

Radix Isatidis, heat-clearing, detoxifying, cooling blood, relieving sore throat. Warm and poisonous spots; high fever and headache; big head plague; purple and dark tongue, rotten throat Dansha; erysipelas; mumps; sore throat; sores, carbuncles; chickenpox; measles; hepatitis; Pneumonia, coma, vomiting, swollen throat, burning eyes, sores; it can prevent and treat epidemic encephalitis B, acute and chronic hepatitis, mumps, and osteomyelitis. ① "Rihuazi Materia Medica": "Treatment of heat and poison in the sky." ② "Book of Materia Medica": "Treatment of Tianxing Datou pyretic poison." ③ "Compendium of Materia Medica": Radix isatidis is indigo root, its functional properties and taste are the same as indigo leaves, and it can enter the liver and stomach blood, but it only clears away heat, detoxifies, prevents epidemics, and kills insects. But the leaves are mainly scattered, and the roots are mainly descending, which is the same as the different ears in the middle. ④ "Classification of Herbal Medicine": Relieve various poisons and malignant sores, disperse toxins and remove internal heat, pound juice or take or apply. ⑤ "Modern Practical Chinese Medicine": Malangen is a cool, antipyretic, antidote, used for erysipelas, puerperal fever, etc. ⑥ "Chinese Medicine Annals": Clear fire and detoxify, cool blood to stop bleeding. Treatment of hot spots, erysipelas, sore throat, big head plague, and hematemesis, epistaxis embolism. ⑦ "Handbook of Commonly Used Chinese Herbal Medicine in Liaoning": Treating hepatitis and mumps.

Prunella vulgaris, clears the liver, dissipates stagnation, diuresis; cures plague, breast abscess, eye pain, jaundice, gonorrhea, high blood pressure embolism; leaves can replace tea. Treatment of lymphatic tuberculosis, goiter, scrofula, goiter, breast abscess, breast cancer, eye pain at night, shame and tears, head dizziness, crooked mouth and eyes, muscle and bone pain, tuberculosis, acute jaundice infectious hepatitis, blood metrorrhagia, red leucorrhea Lowering, blood metrorrhagia, postpartum haemorrhage, distraught, scrofula (whether collapsed or not, or leaking over time), physical weakness, sweat spots and white spots. Recipe attached: The function of Prunella vulgaris is to clear the liver and improve eyesight, use blood stasis to eliminate tumors, diuresis and lower blood pressure.

Anti-wind, efficacy: expelling wind and relieving the surface, eliminating dampness and relieving pain, relieving spasm, and relieving itching. Indications: exogenous wind and cold; headache and body pain; rheumatic arthralgia; joint pain; abdominal pain and diarrhea; intestinal wind and blood; tetanus; rubella and itching; Fangfengjiebiao is characterized by expelling wind, which can dispel wind-cold and dissipate wind-heat, and has similar effects to Nepeta nepeta, so the two medicines are often used together. 2. For rheumatic arthralgia Wind can dispel rheumatism and relieve pain, often cooperate with notopterygium, Fangji, etc. to treat rheumatism arthralgia embolism. 3. For tetanus, trismus, opisthotonus. Preventing wind and treating tetanus has the effect of dispelling wind and relieving convulsions, but it is often used together with herbs such as Tiannanxing, Gastrodia elata, and Baifuzi. In addition, this product also has hemostatic and antidiarrheal effects. If it is used for abdominal pain and diarrhea, it is often used together with white peony root, Atractylodes macrocephala, and tangerine peel.

Schizonepetae, relieves exterior and disperses wind, promotes rash, eliminates sores, and stops bleeding. For colds, measles, poor penetration, blood in the stool, metrorrhagia, epistaxis. : expelling wind; relieving exterior syndrome; penetrating rash; hemostasis. Mainly cold and fever; headache; eye itching; cough; sore throat; measles; carbuncle; sores and scabies; epistaxis; hematemesis; For colds, headaches, measles, rubella, sores. Stir-fried charcoal treats blood in the stool, metrorrhagia, postpartum haemorrhage. ① "Herbal Classic": main cold and heat, rat fistula, scrofula and sores, breaking knots and gathering Qi, blood stasis, and dehumidification. ②"Properties of Medicine": control evil wind and wind, crooked mouth and face, obstinate numbness all over the body, guilty mind and forgetting things, adding strength to make things worse. It is mainly used to ward off evil and poisonous gas, eliminate fatigue, and treat swollen joints; take one and cut it, take five liters of water, boil two liters, and divide it into two servings. And vinegar to seal poison swelling. ③Meng Shen: postpartum apoplexy and stiff body, grind it into powder and take it with wine.

Burdock Fructus, evacuating wind-heat; clearing away heat and detoxifying rashes; Early onset of wind-heat cold and febrile disease; wind-heat or lung-heat cough, poor expectoration; Raw use can moisten the intestines and laxative, especially suitable for red, swollen and sore throat due to heat toxicity, and constipation due to heat knot. It is often used in combination with heat-clearing and detoxifying medicines such as ditin and wild chrysanthemum for those with heat-related sores and swellings that have not yet collapsed.

Reed Rhizome, returns lung meridian, stomach meridian. Function: clearing away heat and promoting body fluid, eliminating restlessness, relieving vomiting, diuretic. Indications: It is used for polydipsia due to febrile disease, vomiting due to stomach heat, cough due to lung heat, pus vomiting due to lung abscess, hot stranguria and astringent pain. [3] Reed root cures cough due to lung heat, lung abscess and vomiting pus: Reed root enters the lung meridian and is good at clearing lung heat, reed root cures fever and polydipsia: reed root is sweet and cold in nature, reed root cures hot stranguria and astringent pain: reed root function clears heat and diuresis, It can be used to treat heat, stranguria, astringent pain, and short red urine. It is often used with Rhizoma Imperatae and Plantago Seed.

Dandelion, sweet, slightly bitter, cold. Heat-clearing and toxic substances removing, eliminating carbuncle and dissipating stagnation. Go into spleen, stomach, kidney three warps. Indications: upper respiratory tract infection, conjunctivitis, mumps, hyperglycemia, mastitis, gastritis, dysentery, hepatitis, cholecystitis, acute appendicitis, urinary tract infection, pelvic inflammatory disease, carbuncle furuncle, pharyngitis, Acute mastitis, lymphadenitis, scrofula, furunculosis, acute conjunctivitis, cold and fever, acute tonsillitis, acute bronchitis, urinary tract infection. The dandelion plant contains various healthy nutrients such as dandelion alcohol, dandelion, choline, organic acid, inulin, etc. It has diuretic, laxative, jaundice-reducing, choleretic and other effects. Dandelion also contains protein, fat, carbohydrates, trace elements and vitamins, etc., and has rich nutritional value. The carotene, C and minerals contained in it can improve indigestion and constipation. In addition, the leaves have the effect of improving eczema and relieving dermatitis, the root has anti-inflammatory effect, and the flowers can be decocted into medicinal juice to remove freckles.

Scutellaria baicalensis, Scutellaria baicalensis has heat-clearing and damp-drying, cooling blood and anti-abortion, detoxification effects. Indications for febrile disease, upper respiratory tract infection, lung-heat cough, damp-heat jaundice, pneumonia, dysentery, hemoptysis, red eyes, restless fetus, high blood pressure, carbuncle, swollen boils and other diseases. The clinical application of Scutellaria baicalensis is better than that of Coptis chinensis, and it does not produce drug resistance. With the help of the characteristics of strong broad-spectrum antibacterial effect, we use it in the fungal culture of miscellaneous bacterial infections, and the effect of using the extract of Scutellaria baicalensis is very good. "Ben Cao Jing Shu": Scutellaria baicalensis, its nature is clear and purifying, so it eliminates evils: it tastes bitter so it dries dampness; yin and cold so it overcomes heat, so it controls all heat. For those with all kinds of heat, pathogenic heat and pervasive heat, jaundice, intestinal withdrawal, and diarrhea are all diseases caused by damp heat. If you analyze the root, all diseases will heal by themselves. Bitter cold can remove dampness and heat, so the small intestine is sharp and the water is self-dispelling, and the source is clear and the flow is clean. For those with closed blood, the excess heat is in the blood system, that is, it heats up the blood chambers, causing amenorrhea. For malignant sores and ulcers, the blood heat will stay and become carbuncles, swollen and rotten; for fire sores, fire qi will damage the blood, and cooling the blood to remove heat will heal itself.

Notopterygium, expelling exterior cold; expelling rheumatism; sharpening joints; relieving pain. Main exogenous wind-cold; headache without sweating; mimeograph cold-damp arthralgia; Fengshui edema; sore swollen toxin. For impotence and nocturnal emission, enuresis and frequent urination, cold pain in the waist and knees, asthma due to kidney deficiency, diarrhea at dawn; external use for treating vitiligo and alopecia areata. Relieve the exterior and dispel cold, expelling wind and dampness, relieving pain. 1. For symptoms such as exogenous wind-cold, aversion to cold and fever, headache and body pain. This product has a strong effect of dispelling wind-cold and relieving pain. It is often used with Fangfeng, Angelica dahurica, Asarum, etc., such as Jiuweiqianghuo Decoction. 2. It is more suitable for joint pain, shoulder and back pain caused by wind-cold-damp evil invasion, especially upper body pain. This product can dispel wind and overcome temperature, dispel cold and relieve pain. It is often used together with Fangfeng, such as Juanbi Decoction. ① "Medicine Properties": "Treatment of wind, aphonia, speechlessness, itching and blood leprosy, paralysis of hands and feet, crooked mouth and face, stubborn numbness all over the body." Convulsions of the fists, weakness of the limbs, redness of the head and eyes, and water vapor in the beams, five labors and seven injuries, deficiency of air-conditioning, sore joints, benefiting the five viscera.

Rhizoma Chuanxiong, blood circulation promoting and blood stasis dispelling; Textual research: From "Tang Ye Materia Medica" Indications: The first choice for treating headaches. Irregular menstruation; amenorrhea dysmenorrhea; postpartum stasis and pain; abdominal mass; chest and hypochondrium pain; headache and dizziness; anemofrigid-damp arthralgia; bruises; carbuncle sores. "The Classic": main apoplexy into the brain headache, cold arthralgia, spasms emergency, metal wounds, women with blood closed and childless. "Bie Lu": In addition to the cold movement in the brain, the wind coming and going on the face, tears coming out of the eyes, excessive tears and saliva, sudden drunkenness, all kinds of cold air, pain in the heart and abdomen, evil in the middle, acute swelling and pain in the chest, wind pain in the hypochondriac, warm Inner cold. Tao Hongjing: Those with bleeding from the root of the tooth have a lot of bleeding. "On the Properties of Medicine": Treat weakness of the waist and feet, hemiplegia, prolapse of the main body clothes, and cold pain in the abdomen. "Rihuazi Materia Medica": cure all wind, all qi, all strains, all blood, nourish five fatigue, strengthen muscles and bones, regulate all channels, break old blood, nourish new blood, grow flesh, nasal flood, vomiting blood and drowning , hemorrhoids, fistula, cerebral abscess, scrofula, galls, sores and scabies, and drainage of pus and blood stasis. "Medical Genesis": Enrich blood, treat blood deficiency and headache. Wang Haogu: search liver qi, nourish liver blood, moisten liver dryness, nourish wind deficiency. "Compendium": dry dampness, stop diarrhea and dysentery, promote qi and relieve depression. Rhizoma Xiongzi is also a medicine for qi in the blood. If the liver is bitter and urgent, it should be supplemented with pungent, so it is suitable for those with blood deficiency; "Zuo Zhuan" says that wheat koji and juqiong can prevent dampness and treat abdominal diseases of river fish. To treat damp diarrhea, every time you add two flavors, it should be like a ring. If the bloody dysentery has passed and the pain persists, it is due to Yin deficiency and Qi stagnation, and the medicine is supplemented with Xiongxiong, and the Qi and blood can be adjusted, and the disease will stop immediately. "Materia Medica Yanyi": Xiongzi is the most used by people today, and the head and face wind cannot be missed, but it must be supplemented by other medicines.

Angelica, the product is the dry root of Umbelliferae Angelica sinensis. Excavate in late autumn, remove fibrous roots and silt, and after the water evaporates slightly, bundle them into small handles, put them in a shed, and slowly smoke them to dry with fireworks. The root of Angelica sinensis is slightly cylindrical, and the upper end of the root is called "guitou", and the main root is called "guishen" or "inch body". The root is called "gui tail" or "gui leg", and the whole is called "quangui". Whole angelica can not only nourish blood, but also activate blood, collectively referred to as harmony blood; Return liver; Heart; Spleen channel. Blood-tonifying medicine; menstruation-regulating medicine; analgesic medicine. Enriching blood; promoting blood circulation; regulating menstruation and relieving pain; moistening dryness and smoothing intestines. Various syndromes of blood deficiency; irregular menstruation; amenorrhea; dysmenorrhea; lumps and lumps; metrorrhagia; abdominal pain due to deficiency and cold; flaccid numbness; numbness of the skin; dryness of the intestine and difficulty in defecation; heavy dysentery after dysentery; carbuncle sores; injuries from falls.

Rehmannia, clearing away heat, promoting body fluid, moistening dryness, smoothing intestines, breaking blood stasis, regenerating, relieving pain, regulating menstruation, gold sores and blood stasis, cooling blood, and stopping bleeding; it has the effect of clearing heat and cooling blood, and is used for febrile diseases and heat entering the camp blood, strengthening heat and fainting, Dry mouth and red tongue. Such as Qingying soup. For the late stage of febrile disease, the remaining heat is not exhausted, the Yin fluid has been injured, the night is hot and the morning is cool, the tongue is red and the pulse is rapid, such as Qinghao Biejia Decoction. It can be used to treat warm and febrile diseases, heat entering the camp and blood, blood heat and poison, vomiting blood and epistaxis, purple and black macule. Such as Sisheng Pill; the effect of nourishing yin and promoting body fluid is used for thirsty wounds with body fluid, internal heat and quenching thirst. Treatment of febrile disease and Yin injury, intestinal dryness and constipation, such as Zengye Decoction. Fresh rehmannia tastes sweet and bitter, and is very cold in nature. Its effect is similar to that of dried rehmannia glutinosa. The effect of nourishing yin is slightly weaker, but it has a stronger effect of clearing heat and promoting body fluid, cooling blood and stopping bleeding.

Gentiana, purging the liver and relieving convulsions. Damp-heat jaundice; urinating pain; genital swelling and itching; under the humid tropics; head swelling and headache due to liver and gallbladder excess fire; red eyes and swelling pain; deafness and ear swelling; hypochondriac pain and bitter mouth; febrile disease convulsions and convulsions. Gentiancao relieves excess fire in the liver and gallbladder, and removes damp-heat in the lower burnt body. Control excessive heat in the liver meridian, convulsions, epilepsy and mania, Japanese encephalitis, headache, red eyes, sore throat, jaundice, dysentery, carbuncle sores, swollen and painful scrotum, and wet itching in the genitals. For damp heat jaundice, pruritus vulvae, vaginal discharge, eczema itching, deafness, hypochondriac pain, bitter mouth, convulsions and convulsions. ① "The Classic"; "mainly cold and heat between the bones, frightening and lame evil spirits, continuing to eliminate injuries, fixing the five internal organs, and killing gu poison." Eliminate small worms in the intestines, benefit liver and gallbladder, stop convulsions and vigilance." ③ "Properties of Medicine": "mainly convulsed epilepsy into the heart in children, strong heat and bone fever, carbuncle; control seasonal heat yellow, aphthous ulcers." ④ "Nihuazi "Compendium of Materia Medica": "Treating guest disobedience, malnutrition, febrile madness, sores and scabies, eyesight, and restlessness." Alcohol poisoning and blood in the stool, blood in the stool due to intestinal wind." ⑦ "Medical Origin": "Treatment of yellow eyes, redness and swelling, eye swelling, stasis and flesh, and unbearable pain." "Indications Secrets" cloud: cure lower rheumatism and damp heat To foot swelling and pain, cold-damp beriberi." ⑧ "Southern Yunnan Materia Medica": "control sore throat, wash sores and scabies." ⑨ "Introduction to Medicine": "control heartache, insect attack heartache, pain in limbs." ⑩" "Compendium": "Treat sore throat, wind-heat and night sweats. Those with weak spleen and stomach for venting and no damp-heat and excess fire should not take it." ① "Lei Gong Pao Shao Lun": "Do not bait it on an empty stomach, it will make people drown." "② "Compendium of Materia Medica": "Guanzhong is the envoy. Evil Rehmannia, Anti-Kwai. "③ "Rihuazi Materia Medica": "Adzuki bean is used as an envoy." "

Radix Paeoniae Rubra, clearing heat and cooling blood; promoting blood circulation and removing blood stasis. Mainly warm and poisonous spots; vomiting blood and epistaxis; intestinal wind and blood; conjunctival congestion and pain; carbuncle sores; amenorrhea; It is used for warming and poisoning spots, vomiting blood and epistaxis, conjunctival congestion and swelling pain, liver depression and hypochondriac pain, amenorrhea dysmenorrhea, abdominal pain in the abdomen, injury from falls, carbuncle sores. 1. "Shen Nong's Materia Medica": "Shen Nong's Herbal Classic": "Shen Nong's Herbal Classic": "Shen Nong's Materia Medica": "Shen Nong's Materia Medica": "Shen Nong's Materia Medica": "Shen Nong's Materia Medica": "Shen Nong's Materia Medica": "Shen Nong's Materia Medica": "Shen Nong's Materia Medica": "Shen Nong's Materia Medica": "Shen Nong's Materia Medica": "Shen Nong's Materia Medica": "Shen Nong's Herbal Classic": "Shen Nong's Herbal Classic": "Shen Nong's Materia Medica": "Shen Nong's Materia Medica": "Shen Nong's Materia Medica": "Shen Nong's Materia Medica": "Paeoniae, bitter and flat. Main evil abdominal pain, except blood numbness, breaking hard cold and heat, hernia, pain relief... Sheng Chuan Gu." Born in Zhongyue, Chuangu and hills, in February and August, the roots are harvested and dried up." 3. Tao Hongjing said: "The best ones come out of Baishan, Jiangshan and Maoshan today. They are white and about a foot long. There are also many red ones in the rest. Small profit." 4. Song Ma Zhi said: "There are two kinds of red and white, and its flowers are also red and white." 5. Su Song said: "Nowadays, it is everywhere, and those born in the Huaihe River win. Red buds grow in spring It is a cluster with three branches and five leaves on the stem, long and narrow like a peony, one or two feet high. It blooms in early summer, and there are several kinds of red, white and purple. The seeds are small like peony seeds. The roots are picked in autumn. There are two types: grass peony and wood peony. Wooden peony has large flowers and dark color, commonly known as peony, and non-peony has golden peony, which is white and fatty; wood peony is purple, thin and veiny."

Guanzhong, heat-clearing and toxic substances removing, cooling blood for hemostasis, parasite killing. Indications 1. Fengreganmao, warm toxin hair spots. This product is bitter and cold. It can clear the excess heat of the qi and detoxify the blood. It can be used for all syndromes caused by warm-heat toxin. San ("Puji Fang"). Single product or combined with mulberry leaves, honeysuckle, etc. can prevent wind-heat and cold; if it is compatible with Radix Isatidis, Folium Isatidis, Comfrey, etc., it can also be used for mumps, warm toxins, spots, and rashes. 2. Blood heat and bleeding. This taste is bitter and slightly cold, and enters the Liver Meridian. It has the function of cooling blood and stopping bleeding. It is mainly used to treat epistaxis, hematemesis, blood in the stool, and metrorrhagia caused by blood heat. It is especially good at treating metrorrhagia and bleeding. For example, "Bencao Tujing" can be used to treat epistaxis, and it can be ground into powder and taken; if it is used with Coptis chinensis, powdered glutinous rice drink can be used to treat hematemesis, such as Guanzhong powder ("Shengji Zonglu"); Compatible with arborvitae leaves; it can be used with Wulingzhi for metrorrhagia and bleeding. 3. Insect disease. This product has the function of killing insects. It is used to kill tapeworms, hookworms, pinworms, roundworms and other intestinal parasites. Can be used in conjunction with anthelmintics. 4. This product can also be used to treat diseases such as burns and scalds and vaginal discharge of women.

Wild chrysanthemum, function of clearing away heat and detoxification, detumescence. It has inhibitory effect on Staphylococcus aureus, Bacillus diphtheriae, Streptococcus, Pseudomonas aeruginosa, Bacillus terrestris and influenza virus. Furuncle; carbuncle; erysipelas; eczema; dermatitis; anemopyretic cold; sore throat; hypertension. Jing Huan of the Song Dynasty said in "Mu Shu Chatter": "The real chrysanthemum prolongs the age, and the wild chrysanthemum leaks people." Dizziness, conjunctival congestion and swelling. Traditional Chinese medicine believes that wild chrysanthemum has the effect of clearing away heat and detoxification, and it is widely used in modern clinical practice to treat carbuncle sores, eczema, cervicitis, prostatitis, anal sinusitis, etc. 1. "Compendium of Materia Medica": Breaks blood and soothes the liver, relieves boils and disperses toxins. The blood in the housewife's abdomen can relieve the poison of the sky and the fire. Washing sores and scabies can also remove wind and kill insects. 2. "Modern Practical Chinese Medicine": It is used to treat swollen and purulent diseases of carbuncle and ulcer. 3. "Suzhou Native Medicinal Materials": Detoxification and Shufeng. Treat eye diseases and dizziness. 4. "Zhejiang Traditional Chinese Medicine Handbook": Evacuate pus and detoxify, reduce swelling and relieve pain. Control carbuncle and treat poison, pemphigus eczema.

Cicada sloughs off, sweet, cold. Return lung, Liver Channel. Function cures mainly dispelling wind and removing heat, relieving sore throat, clearing rash, removing nebula, relieving spasm. For wind-heat cold, sore throat, hoarseness, opaque measles, rubella itching, convulsions and convulsions, and tetanus. (1) For exogenous wind-heat, fever and chills, cough, as well as rubella, skin itching and other diseases. Cicada slough has the effect of evacuating wind-heat, and it is often used in conjunction with mint for wind-heat symptoms; it also has the function of dispelling wind and relieving itching for rubella itching. (2) Used for poor penetration of measles. Cicada sloughs through the hair and has the effect of clearing away heat. Because it is mainly used to dispel wind and heat, it is mostly used for measles who have difficulty in passing through the hair at the beginning. It is often used together with burdock and mint; Comfrey, forsythia and other applications. (3) For sore throat and hoarseness. Cicada slough is suitable for treating sore throat caused by exogenous wind-heat, because it has the effect of dispelling wind-heat and benefiting the throat, it is often used in conjunction with mint, burdock, forsythia, platycodon grandiflorum, and licorice. As for the treatment of hoarseness, it is suitable for those caused by wind evil stagnation in the lungs and loss of lung qi, whichever is used for its function of promoting the lungs and opening the sound. (4) Used for eye redness and swelling, nebula to cover eyes. This product has the effect of improving eyesight and reducing nebula on conjunctival congestion and nebula caused by wind-heat, and nebula on eyes after measles. (5) For tetanus, infantile convulsions, night crying and other diseases. Cicada slough can not only dispel external wind, but also calm internal wind and relieve convulsions. For tetanus with convulsions of the limbs, it can be used with scorpion; .

Baixianpi, Baixianpi comes from "On the Properties of Medicine" and is contained in "Shen Nong's Materia Medica". Mainly used to treat "head wind, jaundice, reversible, dripping. Women's genital swelling and pain, dampness and dead muscles, can not be flexed and stretched to stop walking. Meridians: spleen meridian; lung meridian; small intestine meridian; stomach meridian; bladder meridian. Function: clearing away heat and dampness; expelling wind and relieving itching; detoxification.Indications: rubella caused by wind-heat-damp toxin; eczema; scabies; jaundice; damp-heat numbness.

Licorice root cures cold and heat in internal organs, strengthens muscles and bones, builds muscles, doubles strength, detoxifies, lightens body and prolongs life after long-term use. Used raw for purging fire and heat, cooked for dispelling exterior cold, eliminating sore throat, removing pathogenic heat, slowing righteousness, nourishing yin and blood, nourishing spleen and stomach, and nourishing lungs. Licorice is used for heart qi deficiency, palpitations, intermittent pulse, and spleen and stomach qi deficiency, fatigue and fatigue. The former is often combined with Guizhi, such as Guizhi Gancao Decoction and Zhi Gancao Decoction. The latter is often used together with Codonopsis pilosula and Atractylodes macrocephala, such as Sijunzi Decoction and Lizhong Pills. For asthma and cough. It can be used alone or in combination with other drugs. For example, Erchen Decoction for treating wet phlegm and cough; Linggan Wuwei Jiangxin Decoction for treating cold phlegm, cough and asthma; Salivating licorice and dried ginger soup, etc. In addition, wind-heat cough, wind-cold cough, and heat-phlegm cough are often used in combination. For carbuncle sores, sore throat and so on. Carbuncle sores are often used with honeysuckle and forsythia to play a role in clearing away heat and detoxification, such as Xianfang Huomingyin. For sore throat, it is often used together with orange terrier, such as orange terrier soup. In case of pesticide or food poisoning, it is often mixed with mung beans or decocted with Fangfeng Shui. Used to reconcile the potency of certain drugs. For example, seasoning Chengqi soup uses this product to alleviate the diarrhea effect of rhubarb and Glauber's salt and stimulate the gastrointestinal tract. In addition, this product is also commonly used to reconcile various medicines in many prescriptions. It is used for stomachache, abdominal pain and gastrocnemius spasm acute pain, etc. It is often used together with peony, which can significantly enhance the curative effect of treating contracture acute pain, such as Shaoyao Gancao Decoction.

Fructus Kochia, cold in nature, pungent in the mouth, bitter. Function cures mainly heat-clearing and promoting diuresis, expelling wind and relieving itching. It is used for astringent and painful urination, pruritus vaginal discharge, rubella, eczema, and itchy skin. Promoting urination, clearing away dampness and heat. Treatment of dysuria, gonorrhea, leukorrhea, hernia, rubella, sores, scabies, genital itching. ①"Herbal Classic": "Maintains heat in the bladder, facilitates urination, nourishes the middle, and benefits essence." ②"Bie Lu": "Removes heat in the skin, dispels malignant sores, hernias, strengthens yin, and moisturizes people."③ "On the Properties of Medicine": "Take it together with actinolite, the main husband's impotence can't afford it, nourish qi and strength; treat yin and egg diseases, go to heat, and can be used as soup for bathing." ④ "Rihuazi Materia Medica": "Treatment Ke heat and swollen." ⑤ "Southern Yunnan Materia Medica": "The heat accumulated in the bladder and urination, the wind that washes the skin, treats the women's various meridian heat, clears the tire heat, and is under the humid tropics." 6 "The Original Materia Medica": " Remove accumulated heat in the skin, except for skin dampness and itching." ⑦ "Materia Medica Bei Yao": "Benefiting essence and strengthening yin, removing asthenic heat, diuresis and dredging." ⑧ "Jade catalpa medicine solution": "Treat head swelling , fox hernia and Yin decadence, waist pain and hypochondriac pain, bloody dysentery, malignant sores."

Budisma japonica, clears away heat and nourishes the liver, improves eyesight and relieves nebula. Indications: It is used for conjunctival congestion, swelling and pain, excessive tearing and embarrassment of vision, cloudy eyes, liver deficiency and dark eyes, and dim vision. Clearing the Liver and Improving Eyesight: This product is a special medicine for ophthalmology. It is used for eye diseases caused by blood deficiency and liver heat. It is often mixed with medlar and dodder. To treat eye diseases caused by excessive heat in the liver meridian, it is often paired with fennel seeds, chrysanthemums, etc. ① "Kaibao Materia Medica": "mainly green blind skin nebula, red astringency and multiple tears, disappear red veins in eyes, children's bran beans and malnutrition attack eyes." ②Liu Wansu: "Cure shame and fear of the sun." ③Wang Haogu: "Moisturizes the liver and dryness."

Fructus Chinensis, clears the liver, improves eyesight, and relieves nebula. It is used for red eyes due to liver heat, cloudy eyes, dim vision, and dizziness caused by liver fire. 1. Clearing liver and improving eyesight: Mainly used for inflammation of liver fire, conjunctival congestion, swelling and pain, nebula on eyes, and dim vision. 2. This product can also be used for anger-type hypertension.

Daqing Salt, purging heat; cooling blood; improving eyesight; moistening dryness. Mainly hematuria; hematemesis; gingival hemorrhage; conjunctival congestion, swelling and pain; rheumatism eye rotten string; toothache; constipation. 1. "Shen Nong's Materia Medica": "Rong salt. Mainly improves eyesight, eye pain..." 2. Liang · "Famous Doctors" said: "Rong salt was born in Huyan Mountain, and the northern land of Xiqiang, Jiuquan Fulu City The southeast corner. The North Sea is blue, and the South Sea is red. Picked in October." 3. Tao Hongjing said: "Historical books say that there are nine kinds of salt among captives: white salt, common salt, and those who eat regularly; Soft salt, the main horse spine; there are four kinds of red salt, barley salt, smelly salt, and horse-tooth salt, which are not eaten. The big horse-tooth salt is suspected to be halogen alkali, and the soft salt is suspected to be Rong salt. This Rong salt is also called Hu salt, and its two or three phases are disordered. There are quite a few Rong salt captives today, and they come from Liangzhou and also from Dunhuang. Its shape is made into pieces, or it is like chicken or duck eggs, or it is like water chestnut rice, and its color is purple. It is white, very salty in taste, and smells like chicken rot in the mouth, which is true. It is also true that in the mud of the salt pond in Henan, there is condensed salt like stone flakes, which are all square when broken, and it is blue and black. It is suspected that this is Rong salt. And Badong Qu There is a salt well in the north cliff of Ji County, the salt water is self-condensing, and umbrella salt is produced, with a square of one or two inches, and the center protrudes like an umbrella, and there are also squares like plaster, and chess players."

White oak, also known as chestnut tree and white purple cattail tree. Quercus fabri Hance of the family Fagaceae uses the galls of the fruit as medicine. Distributed in the south of the Yangtze River and the provinces of South China. Indications for malnutrition in children, hernia in adults, and acute conjunctivitis.

Half-side flag, also known as half-side fern, half-side saw, half-side tooth, half-side comb, half-side wind medicine. It is Pteris semipinnata L. of the Pteridaceae Pteridaceae Pteris genus Pteris semipinnata L., and the whole herb is used as medicine. Available in all seasons, washed and used fresh or sun-dried. Nature and flavor are bitter, pungent, cool. Cure mainly heat-clearing and toxic substances removing, reducing swelling and relieving pain. For bacillary dysentery, acute enteritis, jaundice hepatitis, conjunctivitis; external use for bruises, traumatic bleeding, sores, furuncles, eczema, snake bites.

Calamine, odorless, slightly astringent taste. Functions and indications: detoxification, improving eyesight and removing nebula, reducing dampness, relieving itching and suppressing sores. It is used for conjunctival congestion, swelling and pain, red and rotten eyes, pannus pterygium, unrestrained ulcer, dripping pus, eczema, and itchy skin. "Yuyaoyuan Prescription" is the prescription for eye and swelling; "Simple Health Prescription" is the prescription for treating windy eyes and tears; "Simple Health Prescription" for treating dizziness and dizziness; Wet itching "Ren Zhai Zhi Zhi Fang".

Chicken bone grass, clearing heat and promoting dampness, dispelling blood stasis and relieving pain. Mainly used for icteric hepatitis, stomach pain, rheumatic bone pain, bruises, stasis pain, breast pain, heat-clearing and toxic substances removing, soothing the liver and relieving pain. Discomfort in the hypochondrium, distending pain in the epigastric cavity; acute and chronic hepatitis, mastitis. 1. "Nanning City Drug Chronicle": Anti-inflammatory and detoxification, cure infectious hepatitis, bruises and bones. Leaves: pounded cashmere for applying mastitis. 2. "Illustrated Book of Chinese Medicine Plants": Treat rheumatism and bone pain, bruises, blood stasis and internal injuries; and be used as a cooling and antipyretic medicine. 3. "Lingnan Herbal Medicine": clearing stagnation and heat, soothing the liver, harmonizing the spleen, and continuing injury. 4. "Handbook of Commonly Used Chinese Herbal Medicine" by the Guangzhou Army: clearing away heat and dampness, soothing the liver and relieving pain. Treatment of acute and chronic hepatitis, liver cirrhosis, ascites, stomach pain, tingling in urination, and snake bites.

the

Embodiment 1 capsule

The preparation process of the capsule of the present invention is: get 1500g of honeysuckle, 1000g of forsythia, 1200g of mulberry leaves, 1000g of Radix Radix, 1800g of Prunella vulgaris, add 5-10 times the amount of water to soak for 1-2 hours, extract the volatile oil for 2-5 hours, Collect volatile oil, filter the medicinal liquid, and prepare medicinal residues; use medicinal residues and Fangfeng 1200g, Nepeta 1500g, Guanzhong 1400g, Arctium 1000g, Reed Rhizome 1200g, Dandelion 1000g, Scutellaria baicalensis 1800g, Notopterygium 1200g, Chuanxiong 1000g, Angelica 1200g, Habitat 1000g, gentian 1600g, red peony 1000g, wild chrysanthemum 1600g, cicada slough 1500g, white fresh bark 1000g, licorice 1600g, Kochia scoparia 1200g, Budisma japonica 1500g, chrysanthemum chinensis 1000g, big green salt 1000g, white oak 1200g , half-side flag 1500g, calamine 1700g and chicken bone grass 1200g, add 60-90% ethanol, soak for 0.5-1.5 hours, extract twice, each time 1-2 hours, add 5-10 times the amount for the first time, the second time Add 5-10 times the amount for the second time, combine the extracts, and filter; combine and filter the above two filtrates, concentrate the filtrate under reduced pressure to a relative density of 1.10-1.50 at 80°C, precipitate with alcohol twice, adjust The ethanol concentration is 60-90%, and the supernatant is concentrated to a relative density of 1.10-1.50 at 80° C. to obtain an extract; take the above extract, add an appropriate amount of volatile oil and vegetable oil, and add 3% of the total mass of the extract and volatile oil to the vegetable oil, Mix, grind for 10 minutes with a colloid mill, stir constantly, cool to room temperature, pack into capsule shells, 0.4 g per capsule.

Embodiment 2 eye drops

The preparation process of eye drops of the present invention:

a. Take 1200g of honeysuckle, 1600g of forsythia, 1200g of mulberry leaves, 1500g of Radix Radix, 1000g of Prunella vulgaris, 1400g of Fangfeng, 1200g of Schizonepeta, 1700g of Guanzhong, 1500g of Arctium, 1300g of reed root, 1500g of dandelion, 1000g of skullcap, 1200g of Qianghuo, Chuanxiong 1300g, angelica 1500g, habitat 1000g, gentian 1800g, red peony 1200g, wild chrysanthemum 1000g, cicada slough 1400g, white fresh skin 1000g, licorice 1500g, Kochia chinensis 1200g, Mimenghua 1000g, Qingshenzi 1200g, big green salt 1800g, 1600g white oak, 1200g half-pinner, 1200g calamine, 1500g chicken bone grass, add water to extract 2 times, concentrate and filter the extract to obtain extract 1, and the dregs for later use;

b. Soak the above dregs in 60-90% ethanol for 1 hour, extract twice for 2 hours each time, combine the extracts, filter at 80-160 mesh, centrifuge at 6000-10000 rpm, take the supernatant, and Ultrafiltration with an ultrafiltration column with a cut-off molecular weight of 5,000-10,000, the ultrafiltrate is concentrated under reduced pressure and the relative density is 1.35 at 80°C to obtain an extract;

c. Mix extract 1 and extract 2, add 0.05% sodium chloride and 80-100 times distilled water of the total mass of the mixed extract, and add a 5% sodium hydroxide solution to adjust the pH to 6.5-7.5, Then add 0.2% activated carbon and boil for 10 minutes, filter, subpackage, and sterilize to obtain 0.5g/ml eye drops, which are put into 10ml plastic medicine bottles.

Example 3 Tablet

The preparation process of tablet of the present invention: get honeysuckle 1500g, forsythia 1200g, mulberry leaf 1600g, put into 85% ethanol, heat and reflux extraction 2 times, each time 1～2 hour, get extracting solution, medicinal dregs for subsequent use; 1500g of medicinal dregs and isatidis, 1000g of Prunella vulgaris, 1200g of Fangfeng, 1200g of Schizonepeta, 1000g of Guanzhong, 1500g of Burdock, 1500g of Reed Root, 1400g of Dandelion, 1000g of Scutellaria baicalensis, 1500g of notopterygium, 1300g of Rhizoma Chuanxiong, 1500g of angelica, 1500g of habitat, gentian 1000g, 1300g of red peony root, 1000g of wild chrysanthemum, 1200g of cicada slough, 1000g of white fresh bark, 1500g of licorice, 1800g of Kochia scoparia, 1000g of Mimeng flower, 1200g of green chrysanthemum, 1200g of big green salt, 1500g of white oak, 1300g of Banner Banner, furnace Ganshi 1400g, chicken bone grass 1600g, add 10 times the amount of water, heat and reflux extraction 3 times, each time for 1 hour, combine the 3 extractions to obtain the extract; the combined extracts are recovered under reduced pressure to ethanol and concentrated to the pharmaceutical The concentration of the solution is 0.5g/mL. After suction filtration, the relative density of the filtrate is about 1.06 (20°C); the above-mentioned filtrate passes through a macroporous adsorption resin column with a volume of 10L, and first uses deionized water or distilled water with 10 times the volume of the resin column. Elution, and then elution with 95% ethanol with 5 times the volume of the resin column, collecting the ethanol eluate, removing the solvent to obtain the raw drug solution; adding starch and pressing into tablets.

the

Pharmacology and Pharmacodynamics Test

1. Acute toxicity test report

Taking the capsule of the embodiment of the present invention 1 as an object, get 20 mice with the same health of vital signs and carry out the test, 20 mice are divided into four groups, one group of control groups and three groups of test groups, respectively for the test groups 15 mice were fed, and the drug was mixed into the feed of the mice, and the same living conditions were controlled for 20 mice. The first group received 1 times the clinical daily dose, the second group received 2 times the dose, and the three groups 3 times the dose, and then observe each group. After 24 hours, 10 mice were still healthy, and no abnormalities were found in their activities, diet, hair, and excretions, and no toxic reactions were seen.

2. Long-term toxicity test report

Taking the tablet of Example 3 of the present invention as an object, 50 adult rats were selected and randomly divided into 5 groups, one control group and four test groups, with 10 rats in each group, half male and half male. The doses of each group in the test group were 0.1 (500m/K part BW), 0.15 (750m/K part BW), 0.22 (1100m/K part BW), 0.34 (1700m/K part BW) of LD50, administered orally once a day, 20 consecutive days. Then observe for 7 days. As a result of the test, there was no death in each group, and there was no dose-response relationship in each dose group. The drug does not have obvious cumulative toxicity, and long-term use will not produce side effects.

3. Allergy test report

Taking the eye drops of Example 2 of the present invention as the object, 30 healthy guinea pigs were taken for the test, male and female were divided in half, and the back and sides were removed before administration, and they were randomly divided into five groups, with 6 guinea pigs in each group, respectively. In the damaged skin group, the dose was twice as high as 0.5 mg and the dose as low as 1 mg was twice as high, and the dose as intact skin was twice as high as 0.5 mg and the dose as low as twice as 1 mg was grouped. After carrying out subcutaneous administration to back four groups respectively, once a day, continuously 7 days, observe the situation of each group, the result guinea pigs all survive, and the skin of guinea pigs of each group does not appear any discomfort, and the guinea pigs' food intake, activity, respiration and body weight No obvious abnormality occurred. The results showed that the drug was not sensitizing.

Pharmacological and pharmacodynamic tests have shown that the drug does not have any toxic effects, sensitization and adverse reactions, and is safe for clinical use.

the

clinical information

1. Materials and methods

1.1 Information

Selected from May 2010 to May 2011, a total of 200 patients with acute conjunctivitis treated in our hospital. Among them, there were 110 males, 90 females, 50 patients aged 10-25, 80 patients aged 26-40, and 70 patients over 41 years old. Clinical manifestations include severe pain, photophobia, tears and other severe irritation symptoms and watery secretions; eyelid redness and swelling, conjunctival hyperemia, edema, subconjunctival point, sheet or extensive hemorrhage; corneal diffuse punctate epithelial shedding, fluorescence Pigmentation, preauricular or submandibular lymph node enlargement. The patients were randomly divided into two groups, a treatment group and a control group, with 120 people in the treatment group and 80 people in the control group.

1.2 Curative effect standard

Cure: the disease is cured and relieved; effective: the disease is effectively alleviated, with obvious relief; invalid: the disease has no effect at all.

1.3 Test method

The treatment group was divided into three groups, which were treated with the medicines of Examples 1-3 of the present invention, and the control group was divided into two groups, which were treated with traditional medicines.

1.3.1 Treatment group:

One group of treatment: 40 people in this group were treated with the capsules of Example 1 of the present invention. Take 0.5g as one capsule, three times a day, two capsules at a time, 7 days as a course of treatment, 1-3 courses of treatment. After taking the medicine, among 36 people's symptoms, 2 people were effectively relieved, and 2 people were ineffective. During the medication, no side effects occurred. Follow up half a year, recovery from illness does not have recurrence.

Treatment group two: 40 people in this group were treated with the eye drops of Example 2 of the present invention. Prepare eye drops of 0.5g/ml, put it into a 10ml plastic medicine bottle, and drop 3-4 drops to the corner of the eye at a time, three times a day, 7 days as a course of treatment, 1-3 courses of treatment. After taking the medicine, among 37 people's symptoms, 2 people were effectively relieved, and 1 person was ineffective. During the medication, no side effects occurred. Follow up half a year, recovery from illness does not have recurrence.

Three groups of treatment: 40 people in this group were treated with the tablet of Example 3 of the present invention. 0.4g tablet, three times a day, two tablets at a time, 7 days as a course of treatment, 1-3 courses of treatment. After taking the medicine, among 37 people's symptoms, 1 person was effectively relieved, and 2 people were ineffective. During the medication, no side effects occurred. Follow up half a year, recovery from illness does not have recurrence.

1.3.2 Control group:

Control group: 40 people in this group were treated with sulfacetamide sodium. The content is 10%-20%, every 2-3 hours or every hour eye drops 1 time, the treatment lasts for 4 weeks. During the medication, 10 people had local irritation, such as burning sensation, pain and other phenomena. After the medication, 25 people were cured, 7 people were relieved, and 8 people were ineffective. Following up this year, 3 of the 25 people who recovered had relapsed.

Control group two: 40 people in this group were treated with aureomycin. Apply to the inside of the eyelid, 1-2 times a day. Treatment is carried out for 4 weeks. During the medication, 8 people had local congestion, eye itching, edema and other discomfort symptoms. After the medication, 28 people were cured, 7 people's symptoms were relieved, and 5 people were ineffective. In the past six months, 5 people relapsed.

Through comparative tests, it can be known that, compared with traditional medicines, the traditional Chinese medicine composition of the present invention has the characteristics of quick effect, good curative effect, no side effect and little recurrence.

2. Specific cases

Case 1 Li, female, 26 years old, suffered from acute conjunctivitis. Adopt the eye drop of embodiment 2 of the present invention to treat. Configure eye drops of 0.5g/ml, 3-4 drops at a time, three times a day, 7 days as a course of treatment, 2 courses of treatment, cure, no discomfort during the medication process.

Case 2 Sun, man, 40 years old, suffers from acute conjunctivitis. Adopt the capsule of embodiment 1 of the present invention to treat. 0.5g capsules, three times a day, two capsules at a time, 7 days as a course of treatment, after 3 courses of treatment, the disease recovered, and there was no discomfort during the medication.

Case 3 Zhang, male, 30 years old, suffered from acute conjunctivitis. Adopt the tablet of embodiment 3 of the present invention to carry out treatment. With the dose of 0.4g tablet, three times a day, two tablets at a time, 7 days as a course of treatment, the treatment is carried out for 3 courses of treatment. During the medication process, there is no sense of discomfort, and after the medication, the disease is cured.

the

The above descriptions are only preferred embodiments of the present invention, and are not intended to limit the present invention. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principles of the present invention shall be included in the protection of the present invention. within range.

Claims (9)

1. a Chinese medicine composition for the treatment of acute conjunctivitis, it is characterized in that, in described Chinese medicine composition, the ratio of weight and number of various crude drug is: 10～25 parts of Flos Loniceraes, 10～25 parts of Fructus Forsythiaes, 10～25 parts, Folium Mori, 10～25 parts of Radix Isatidis, 10～25 parts of Spica Prunellaes, 10～25 parts of Radix Saposhnikoviaes, 10～20 parts of Herba Schizonepetae, 10～20 parts of Rhizoma Osmundae, 10～20 parts of Fructus Arctiis, 10～20 parts of Rhizoma Phragmitiss, 10～25 parts of Herba Taraxacis, 10～20 parts of Radix Scutellariaes, 10～20 parts of Rhizoma Et Radix Notopterygiis, 10～25 parts of Rhizoma Chuanxiongs, 10～25 parts of Radix Angelicae Sinensis, 10～25 parts, the Radix Rehmanniae, 10～25 parts of Radix Gentianaes, 10～25 parts of Radix Paeoniae Rubra, 10～25 parts of Flos Chrysanthemi Indicis, 10～25 parts of Periostracum Cicadaes, 10～20 parts of Cortex Dictamni, 10～20 parts, Radix Glycyrrhizae, 10～20 parts of the Fructus Kochiae, 10～25 parts of Flos Buddlejaes, 10～20 parts of Semen Celosiae, 10～25 parts of halites, 10～20 parts of white oaks, 10～20 parts of Herba Pteridis Semipinnataes, 10～20 parts of 10～25 parts of Calaminas and Herba Abris.

2. the Chinese medicine composition for the treatment of acute conjunctivitis according to claim 1, it is characterized in that, in described Chinese medicine composition, the ratio of weight and number of various crude drug is: 10～15 parts of Flos Loniceraes, 20～25 parts of Fructus Forsythiaes, 10～25 parts, Folium Mori, 15～25 parts of Radix Isatidis, 20～25 parts of Spica Prunellaes, 10～20 parts of Radix Saposhnikoviaes, 10～15 parts of Herba Schizonepetae, 10～20 parts of Rhizoma Osmundae, 10～20 parts of Fructus Arctiis, 10～20 parts of Rhizoma Phragmitiss, 10～15 parts of Herba Taraxacis, 10～15 parts of Radix Scutellariaes, 15～20 parts of Rhizoma Et Radix Notopterygiis, 20～25 parts of Rhizoma Chuanxiongs, 20～25 parts of Radix Angelicae Sinensis, 10～15 parts, the Radix Rehmanniae, 10～25 parts of Radix Gentianaes, 10～25 parts of Radix Paeoniae Rubra, 10～20 parts of Flos Chrysanthemi Indicis, 10～15 parts of Periostracum Cicadaes, 10～15 parts of Cortex Dictamni, 15～20 parts, Radix Glycyrrhizae, 10～15 parts of the Fructus Kochiae, 20～25 parts of Flos Buddlejaes, 10～15 parts of Semen Celosiae, 10～20 parts of halites, 10～15 parts of white oaks, 15～20 parts of Herba Pteridis Semipinnataes, 15～20 parts of 10～25 parts of Calaminas and Herba Abris.

3. the Chinese medicine composition for the treatment of acute conjunctivitis according to claim 1 and 2, it is characterized in that, in described Chinese medicine composition, the ratio of weight and number of various crude drug is: 10～25 parts of Flos Loniceraes, 10～20 parts of Fructus Forsythiaes, 10～20 parts, Folium Mori, 10～20 parts of Radix Isatidis, 10～20 parts of Spica Prunellaes, 10～25 parts of Radix Saposhnikoviaes, 10～20 parts of Herba Schizonepetae, 15～20 parts of Rhizoma Osmundae, 10～15 parts of Fructus Arctiis, 15～20 parts of Rhizoma Phragmitiss, 10～20 parts of Herba Taraxacis, 10～20 parts of Radix Scutellariaes, 10～20 parts of Rhizoma Et Radix Notopterygiis, 10～25 parts of Rhizoma Chuanxiongs, 10～25 parts of Radix Angelicae Sinensis, 10～25 parts, the Radix Rehmanniae, 10～20 parts of Radix Gentianaes, 10～20 parts of Radix Paeoniae Rubra, 10～25 parts of Flos Chrysanthemi Indicis, 10～25 parts of Periostracum Cicadaes, 10～20 parts of Cortex Dictamni, 10～20 parts, Radix Glycyrrhizae, 10～20 parts of the Fructus Kochiae, 10～25 parts of Flos Buddlejaes, 10～20 parts of Semen Celosiae, 10～25 parts of halites, 10～20 parts of white oaks, 10～20 parts of Herba Pteridis Semipinnataes, 10～20 parts of 10～20 parts of Calaminas and Herba Abris.

4. a preparation method for the Chinese medicine composition of the treatment acute conjunctivitis as described in claim 1-3 any one, is characterized in that, described Chinese medicine composition dosage form is tablet, and described preparation method comprises:

A, by Flos Lonicerae, Fructus Forsythiae and Folium Mori are put into the ethanol heating and refluxing extraction of 60%-90%, obtain extracting solution 1;

B, get other crude drug again, add water heating and refluxing extraction, obtain extracting solution 2;

C, extracting solution 1 and extracting solution 2 merged, decompression recycling ethanol concentrated sucking filtration absorption, obtain raw material medicinal liquid; Add dextrin or starch tabletting.

5. the preparation method of the Chinese medicine composition for the treatment of acute conjunctivitis according to claim 4, is characterized in that, in described step a, by Flos Lonicerae, Fructus Forsythiae and Folium Mori are put into 10 times of amount ethanol, heating and refluxing extraction 2 times, each 1～2 hour.

6. the preparation method of the Chinese medicine composition for the treatment of acute conjunctivitis according to claim 4, is characterized in that, in described step b, crude drug described in other is put into 10 times of water gagings, heating and refluxing extraction 3 times, each 30 minutes～1 hour.

7. the preparation method of the Chinese medicine composition for the treatment of acute conjunctivitis according to claim 4, it is characterized in that, in described step c, extracting solution 1 and extracting solution 2 are merged, decompression recycling ethanol to be concentrated into liquor strength be 0.5g crude drug/mL, after sucking filtration, when the relative density of filtrate is about 20 ℃ 1.08; The macroporous adsorptive resins that above-mentioned filtrate is 10L through volume, first uses deionized water or the distilled water eluting of 10 times of resin column volumes, then uses 95% ethanol elution of 5 times of resin column volumes, collects ethanol elution, removes solvent, obtains raw material medicinal liquid; Add starch or dextrin tabletting.

8. a preparation method for the Chinese medicine composition of the treatment acute conjunctivitis as described in as arbitrary in claim 1-3, is characterized in that, the dosage form of described Chinese medicine composition is eye drop, and described preparation process is:

A, get described crude drug and add water extraction 2 times, by extracting solution thickening filtration, obtain extractum 1, medicinal residues are standby;

B, the medicinal residues of described step a are added to 60-90% soak with ethanol 1 hour, extract twice, each 2 hours, merge extractive liquid,, 80-160 order filters, and 6000-10000 rev/min centrifugal, gets supernatant, through the molecular weight that dams, be the ultrafiltration post ultrafiltration of 5000-10000,1.35 extractum 2 when ultrafiltrate concentrating under reduced pressure relative density is 80 ℃;

C, extractum 1 and extractum 2 is mixed, add 0.05% sodium chloride and the 80-100 distilled water doubly that mix extractum gross mass, and to add concentration be that to regulate PH be 6.5-7.5 to 5% sodium hydroxide solution, add again 0.2% active carbon to boil 10 minutes, filter packing, sterilizing, obtains eye drop.

9. according to the Chinese medicine composition of the treatment acute conjunctivitis described in claim 1-3 any one, it is characterized in that, the dosage form of described Chinese medicine composition is: tablet, sugar coated tablet, film coated tablet, enteric coated tablet, capsule, hard capsule, soft capsule, oral liquid, suck agent, granule, electuary, honey pill agent, powder, sublimed preparation, solution, injection, suppository, plaster, syrup, powder or patch.