CN102743499A - Chinese medicinal herb drug for treating soft tissue internal injury blood stasis and cerebral hemorrhage - Google Patents
Chinese medicinal herb drug for treating soft tissue internal injury blood stasis and cerebral hemorrhage Download PDFInfo
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Abstract
The invention discloses a Chinese medicine herb drug for treating soft tissue internal injury blood stasis and cerebral hemorrhage and a preparation method of the Chinese medicine herb drug. The Chinese medicine herb drug comprises the following principal herbs by weight: 10-20 parts of Indian abutilon root, 6-15 parts of sappanwood and 10-20 parts of mullein mightbrier leaf. The preparation method comprises the steps as follows: extracting active ingredients of Chinese medicine herbs by water extraction or/and alcohol extraction, and preparing into various oral preparations. The Chinese medicine herb drug is mainly used for treating various pains and blood stasis caused by soft tissue internal injury blood stasis and cerebral hemorrhage, has the characteristics of definite treatment effect, quick action, high healing rate and convenience in taking, and can achieve the aim of radical treatment. The multi-year clinical test proves that the total efficiency is 90.6%. The Chinese medicine herb drug has the advantages of easily available raw materials, low cost, green and environmental protection, low drug dose, low production cost and good economic and social benefits.
Description
Technical field
The invention belongs to the pharmaceutical technology field, relate to a kind of herbal composite, specifically, relate to medicine of a kind of Chinese herbal treatment soft tissue internal injury blood stasis and cerebral hemorrhage and preparation method thereof.
Background material
Acute soft tissue internal injury blood stasis and cerebral hemorrhage are the commonly encountered diseases of traumatology.The modal symptom of acute soft tissue internal injury blood stasis and cerebral hemorrhage is pain, swelling, dysfunction.Cerebral hemorrhage also is cerebral hemorrhage, be meant rupture of blood vessel in brain after, blood flows in the brain matter.About 80% patient occurs in cerebral hemisphere, and about 20% patient occurs in XIAONAO and brain stem.The cause of disease of cerebral hemorrhage is a lot, in case abrasive hemorrhage, can cause brain local blood circulation obstacle, cause acute brain internal injury blood stasis symptom, be common how with hemiplegia, aphasia, stupor etc.Therapeutic Method has two kinds, and a kind of is operation, and another kind is to take medicine.When patient's intracerebral hemorrhage 40-100CC, adopt operation to open cranium usually, exist medical expense big, sequela is more serious, the mortality rate problem of higher.Though the patient who has has kept life, Cranial nerve injury as birth trauma in various degree can appear in about 90% patient, causes to can't take care of oneself or become the plant man.When patient's intracerebral hemorrhage 5-40CC, adopt intravenously administrable usually, about 30% patient can cure, and about 50% patient can't cure, and about 20% the patient state of an illness on the contrary can increase the weight of, even causes death, and its curative effect is low.In addition, the patient of intracerebral hemorrhage is through taking modern patent medicine or Western medicine etc., and its medicine time is long, and sb.'s illness took a favorable turn slowly, and cure rate generally has only 10-20%, and its curative effect is low equally.
The internal injury blood stasis that soft tissue internal injury blood stasis and muscle internal injury blood stasis are meant human body skin or subcutaneous tissue, muscle, the joint grain is clashed into suddenly and reason such as compressing causes; Be commonly called as 100 days injured in the sinews or bones, this in other words sick recover slow.At present, the medicine of wound is many, each has something to recommend him in the treatment of selling on the market, and great majority all have certain curative effect.Prior treatment method mainly is a Dressed plaster, or medicinal liquid puts on the skin outward, or Chinese traditional medicine wet compress is with smoked etc., but rapidly alleviating pain, healing has seldom seriously influenced patient's live and work as early as possible.
Motherland's medical science thinks, pain is because human body muscle arteries and veins is impaired, and qi and blood circulation is smooth and due to stagnating; Swelling is that the obstructed institute of QI and blood causes because damage back scabies blood blocks; If deficient qi and blood, the damp that is affected by the cold forms the numbness resistance of network road, makes the meridians contraction anxious, and work is swollen has a pain, and can cause the joint joint stuffiness.Modern medicine is thought; Local organization cell microstructure damage of damage back and microtubule break, hemorrhage, and histiocyte congestion and edema and degeneration necrosis cause impaired local swelling, pain, simultaneously; The local organization cell discharges inflammatory mediator; The metabolite gathering causes interior environment change, causes the damaging cells dysbolismus, thereby increases the weight of local symptom and sign and pathological change.Aspect treatment, modern medicine then often adopts anti-inflammatory analgesic class Drug therapy; The traditional Chinese medical science is advocated invigorating blood circulation scabies method, and mostly external used medicine is to be applied to the partial medicine of injury, and for oral administration and external medication are also arranged, and in treating trauma, occupies critical role, and the traditional Chinese medical science and treatment by Chinese herbs are the characteristics of Chinese cerebral hemorrhage and the treatment of soft tissue internal injury blood stasis.The starting point in diagnosis had both seen that expectorant scabies impatency brain network or brain network are damaged, the domination of pathogen sign outside the blood oozing from the body openings or subcuta neous tissue arteries and veins, paid attention to the syndrome of yin and yang qi and blood disorder again.The Therapeutic Principle is a treating both the principal and secondary aspects of a disease, and Comprehensive Treatment is integrally-regulated, is clinical syndrome differentiation treatment method of treatment with methods such as heat-clearing and toxic substances removing, invigorating blood circulation scabies, the purging FU-organs that reduces phlegm, consciousness and resuscitation restoring, suppressing the hyperactive liver and subsiding YANG, the diuretic that reduces phlegm.
Chinese patent CN20081005025608, a kind of mediation stagnation of QI blood stasis treatment soft tissue, muscle injury medicine; Form by the following weight parts crude drug: Corium elephatis 15-25, Fructus Cnidii 8-12, Lignum Aquilariae Resinatum 14-25, Rhizoma Dioscoreae 8-12, Radix Achyranthis Bidentatae 8-12, Plumula Nelumbinis 3-7, volt 03-7, injustice SIZI 8-12, Radix Ginseng Rubra 8-12, Flos Caryophylli 8-12, Radix Aucklandiae 8-12, Radix Salviae Miltiorrhizae 8-12, Radix Angelicae Sinensis 8-12, Herba Cistanches 8-12, Rhizoma Cyperi 3-7, Radix Notoginseng 14-20, Massa Medicata Fermentata 3-7, Radix Glycyrrhizae 3-7, Borneolum Syntheticum 3-7, Moschus 0.1-0.2; Its preparation method is: the said medicine prescription is taken by weighing, pulverizing, is smalls altogether.Cure mainly and be: internal injury, damaged lung, bone damage, skin and flesh cancerous protuberance, the injury of tendon and muscle, muscle are swollen, muscle gathers, muscle knob, version of tendon and muscle, muscle dodge, muscle is twisted, the various pain of soft tissue; It is few to have medication, cheap, makes simply, does not have toxic and side effects, fire-toxin not to injure internal organs, removes the stagnation of QI, leukemia, does not stay the advantage of sequela and determined curative effect.
Chinese patent CN20061003701301, the medicine of treatment cerebral hemorrhage is mainly processed by the raw material of following weight parts: ground steady root 8-l2 part, Herba Pileae Scriptae l0-20 part; Radix Acanthopanacis Trifoliati l0-l5 part, Radix Cirsii Japonici 6-20 part, Radix Salviae Miltiorrhizae 15-25 part; Radix Ilicis Pubescentis l0-20 part, Ramulus Mori 20-30 part, Herba Leonuri l0-l5 part; Fructus Ligustri Lucidi 12-20 part, Radix Achyranthis Bidentatae l0-20 part, the Pu l0-l5 of stone battalion part.We have the merit of hematocele, vessel softening, dredge the meridian passage, consciousness and resuscitation restoring, good in strengthening stomach and tonifying kidney in cooling blood for hemostasis, the rapid crazy brain.No matter patient's brain inner product blood volume what, when opening brainpan at the end, the patient is in 2-20 days, as long as stable disease even the plant man inserts stomach and irritates the clothes and the stream juice medicinal liquid of swallowing, is taken medicine of the present invention, curative effect is best, effective percentage reaches 96.5%.
Chinese patent CN20lll0273420.3; A kind of powder for dispersing blood stasis that is used for soft tissue injury and cervical spondylosis mainly is to be processed by following bulk drugs: Herba Taraxaci 1150-1350 part, Radix Et Rhizoma Rhei 400-600 part, Myrrha 400-600 part, Radix Notoginseng 400-600 part, Eupolyphaga Seu Steleophaga 400-600 part, geranium 725-925 part.Have that significant dissipating blood stasis stimulates the menstrual flow, the effect of pain relieving eliminating impediment.Be applicable to pain, swelling, inflammation due to cervical spondylosis, osteoarthritis, lumbar muscle strain, prolapse of lumbar intervertebral disc, rheumatic arthritis, hyperosteogeny, gout, the scapulohumeral periarthritis; And fall spit of fland damage, hematocele and become that the stasis of blood, long-pending piece do not loose, the stagnant disease of the joint stasis of blood.Toxic and side effects is little, has less flavour of a drug number and curative effect preferably, is suitable for life-time service, is a kind of safe and effective medicine.
Summary of the invention
The object of the invention: be to soft tissue internal injury blood stasis and cerebral hemorrhage can reach determined curative effect, produce effects is fast, price is low and medicine of a kind of Chinese herbal treatment soft tissue internal injury blood stasis and cerebral hemorrhage and preparation method thereof is provided.
The present invention is achieved in that
The medicine of a kind of Chinese herbal treatment soft tissue internal injury blood stasis and cerebral hemorrhage, main former medicine component and proportioning parts by weight: Radix abutili indici 10-20 part, Lignum Sappan 6-15 part and mullein mightbrier leaf 10-20 part.
The medicine of above-described Chinese herbal treatment soft tissue internal injury blood stasis and cerebral hemorrhage, described former medicine component and proportioning parts by weight are: Radix abutili indici 16-18 part, Lignum Sappan 8-10 part and mullein mightbrier leaf 15-16 part.
The method for preparing of the medicine of above-described Chinese herbal treatment soft tissue internal injury blood stasis and cerebral hemorrhage is carried or/and pure extracting method extracts the Chinese herbal medicine active ingredient with water, is prepared into oral liquid, tablet, granule, capsule and powder.
The method for preparing of above-described oral liquid comprises: raw material Chinese herbal medicine Radix abutili indici, Lignum Sappan and mullein mightbrier leaf are screened respectively, added 8-12 water doubly by the total umber raw material of formulation weight, the control temperature was boiled 1-2 hour for 75-90 ℃; Filter, filtering residue adds 6-8 water doubly once more and boiled again 1-2 hour at temperature 75-90 ℃, filters; Merge extractive liquid,, being evaporated to relative density at temperature 60-78 ℃ is 1.05-1.10, by the conventional method batching; Bottling, dress box and vanning obtain the oral liquid product; Perhaps concentrating under reduced pressure is obtained the clear paste that relative density is 1.15-1.25, add Chinese herbal medicine 10-20 pure water dilution doubly, by the conventional method batching, antibacterial, bottling, dress box and vanning obtain the oral liquid product.
The method for preparing of above-described powder or capsule comprises: raw material Chinese herbal medicine Radix abutili indici, Lignum Sappan and mullein mightbrier leaf are screened respectively, added 8-12 water doubly by the total umber raw material of formulation weight, boiled 1-2.5 hour at temperature 75-90 ℃, cross and filter water cooking liquid; Filtering residue adds total raw material 5-10 55-70% ethanol water doubly again, temperature 50-60 ℃ alcohol extraction 1-2 hour, filter, resulting alcohol extract uses 50-60 ℃ of concentrating under reduced pressure to obtain relative density to be 1.05-1.15 extractum; Extractum is added in the water cooking liquid, obtain the clear paste that relative density is 1.15-1.25 at 60-85 ℃ of concentrating under reduced pressure, hot air drying is pulverized, and adds adjuvant and mixes, sieve, and packing, dress box and vanning obtain powder or capsule product; Perhaps raw material Chinese herbal medicine Radix abutili indici, Lignum Sappan and mullein mightbrier leaf are screened respectively, hot air drying is pulverized, sieve, and packing, dress box and vanning obtain powder or capsule product.
Above-described powder or capsule product add the adjuvant mix homogeneously by conventional method, sieve, and pelletize or film-making, hot air drying, packing and outer package obtain granule or tablet product.
Medicine of the present invention is for oral administration, one-tenth body weight for humans person more than 50 kilograms, and day clothes 3 times, each 4-5 grain or sheet, powder is a bag, takes after mixing it with water with yellow wine or warm water:
The function of medicine of the present invention: Shujin, invigorate blood circulation, circulation of qi promoting, analgesia and repercussive.
Medicine of the present invention cures mainly: the various pain blood stasis of internal injury cerebral hemorrhage and soft tissue internal injury.
The points for attention of medicine of the present invention: the patient please uses under physician guidance, contraindication in pregnancy.
The effect of Chinese herb medicine of the present invention and pharmacology explanation thereof:
Radix abutili indici: Radix abutili indici (Abutilon indicum (L.) Sweet), calling is mill grass roots and medicated cap son shield head.Main product in Yunnan, Guangxi, Fujian; Be distributed in ground such as Fujian, Taiwan, Guangdong, Hainan, Guangxi, Guizhou, Yunnan.
Meridian distribution of property and flavor: sweet in the mouth, property is flat, and is nontoxic; Go into spleen, lung, urinary bladder channel.
Effect cures mainly: clearing away heat-damp and promoting diuresis, sensible invigorating blood circulation; Cure mainly the xeropulmonary cough, stomachache, stomachache is had loose bowels stranguria, hernia, traumatic injury, Hiccough and deaf.
Lignum Sappan; Lignum Sappan (Caesalpinia sapptanL.) is the heartwood of leguminous plant Lignum Sappan.Another name is Soviet Union's a tree, used in making timber for boats, the Soviet side, lignum sappan, palm fibre wood, Ramulus et Folium Bischofiae Javanicae, red bavin, LIGNUM SAPPAN and the Wen Shu that falls; Be distributed in river valley, Jinsha jiang River, Yunnan and river valley, Red River.There is cultivation on ground such as Fujian, Taiwan, Guangdong, Hainan, Guangxi, Sichuan, Guizhou and Yunnan.
Meridian distribution of property and flavor: sweet in the mouth, salty, property is flat, and is nontoxic; Go into the heart, liver, harmonization of the stomach large intestine channel.
Effect cures mainly: function type of having Flos Carthami, few with then can and blood, many with then can removing blood stasis; Blood circulation promoting and blood stasis dispelling, subduing swelling and relieving pain; Cure mainly married woman's amenorrhea due to stagnation of blood, dysmenorrhea, postpartum stagnation cardiac and abdominal pain, puerperal blood faints, carbuncle, traumatic injury, tetanus.
Mullein mightbrier leaf: mullein mightbrier leaf (Solanum verbascifolium), call and be king's leaf, Radix Et Rhizoma Rhei leaf, mullein mightbrier leaf, stone cigarette, smelly cigarette, Folium solani verbascifolii, warm blade root, Mao Yeshu, native eggplant and husband's palpus.Be distributed in ground such as Fujian, Taiwan, Guangdong, Hainan, Hong Kong, Guangxi and Yunnan.
Meridian distribution of property and flavor: acrid in the mouth, property is flat.
Function cures mainly: detumescence, detoxifcation; Cure mainly general edema with yellowish skin, gout, metrorrhagia, treating swelling and pain by traumatic injury, toothache, scrofula, carbuncle skin ulcer, eczema, dermatitis.
The advantage of medicine of the present invention and good effect:
1, medicine of the present invention to the various pain blood stasis of internal injury cerebral hemorrhage and soft tissue internal injury, can reach determined curative effect, produce effects is fast, cure rate is high and the characteristics of taking convenience, and the patient is got well, and reaches the purpose of radical cure for the ancient secret recipe of succession.Through clinical for many years, medication is few, and effect is remarkable.In clinical totally 76 example tests, total effective rate is 90.6%.
2, the prescription of medicine of the present invention is unique, and raw material obtains easily, and is with low cost, and environmental protection has economic benefit and social benefit.
The specific embodiment
One, preparation embodiment
Embodiment 1: the preparation of oral liquid
1, former medicine component and proportioning weight:
1.6 kilograms of 1.7 kilograms of Radix abutili indicis, 0.8 kilogram of Lignum Sappan and mullein mightbrier leafs.
2, method for preparing:
Raw material Chinese herbal medicine Radix abutili indici, Lignum Sappan and mullein mightbrier leaf are screened respectively, added in the saucepan, add the water of 10 times of former medicine weight sums again, under 95 ℃ of conditions of temperature, boiled 1.5 hours, filter; Filtering residue adds the water of 7 times of former medicine weight sums once more, under 95 ℃ of conditions of temperature, boils again 1 hour, filters, and merges and boils liquid, and being evaporated to relative density 70 ℃ of temperature is 1.10, by the conventional method batching, and bottling, dress box and vanning obtain the oral liquid product.
Embodiment 2: the preparation of powder
1, former medicine component and proportioning weight:
1.8 kilograms of 1.2 kilograms of Radix abutili indicis, 1.0 kilograms of Lignum Sappans and mullein mightbrier leafs.
2, method for preparing
Raw material Chinese herbal medicine Radix abutili indici, Lignum Sappan and mullein mightbrier leaf are screened respectively, washing, respectively at 90 ℃ of hot air dryings of temperature to containing moisture less than 11%, pulverize with the machine of morcelling, mix, cross 120 mesh sieves, packing 5 gram/bags pack, and adorn box and vanning and obtain powder product.
Embodiment 3: the preparation of capsule
1, former medicine component and proportioning weight:
1.4 kilograms of 1.9 kilograms of Radix abutili indicis, 1.2 kilograms of Lignum Sappans and mullein mightbrier leafs.
2, method for preparing
Raw material Chinese herbal medicine Radix abutili indici, Lignum Sappan and mullein mightbrier leaf are screened respectively, washing, respectively at 85 ℃ of hot air dryings of temperature to containing moisture less than 11%, pulverize with the machine of morcelling, mix, cross 160 mesh sieves, divides encapsulatedly, bottle, adorn box and vanning and obtain the capsule product.
Embodiment 4: the preparation of granule
1, former medicine component and proportioning weight:
1.7 kilograms of 1.1 kilograms of Radix abutili indicis, 1.1 kilograms of Lignum Sappans and mullein mightbrier leafs.
2, method for preparing
Raw material Chinese herbal medicine Radix abutili indici, Lignum Sappan and mullein mightbrier leaf are screened respectively, added the water of 8 times of former medicine weight sums, boiled 2.0 hours, cross and filter water cooking liquid 86 ℃ of temperature; Filtering residue adds 60% ethanol water of 8 times of raw materials again, 50 ℃ of alcohol extractions of temperature 1.5 hours, filters, and it is 1.10 extractum that resulting alcohol extract uses 65 ℃ of temperature concentrating under reduced pressure to obtain relative density; Extractum is added in the water cooking liquid, and obtaining relative density at 70 ℃ of concentrating under reduced pressure of temperature is 1.20 clear paste, and hot air drying is pulverized, and adds adjuvant and mixes, and after sieving, by the conventional method pelletize, hot air drying sieves, and packing and outer package obtain the granule product.
Embodiment 5: the preparation of tablet
1, former medicine component and proportioning weight:
1.5 kilograms of 1.6 kilograms of Radix abutili indicis, 0.9 kilogram of Lignum Sappan and mullein mightbrier leafs.
2, method for preparing
Raw material Chinese herbal medicine Radix abutili indici, Lignum Sappan and mullein mightbrier leaf are screened respectively, added the water of 10 times of former medicine weight sums, boiled 1.5 hours, cross and filter water cooking liquid 80 ℃ of temperature; Filtering residue adds 65% ethanol water of 10 times of raw materials again, 60 ℃ of alcohol extractions of temperature 1.0 hours, filters, and it is 1.15 extractum that resulting alcohol extract uses 60 ℃ of temperature concentrating under reduced pressure to obtain relative density; Extractum is added in the water cooking liquid, and obtaining relative density at 85 ℃ of temperature concentrating under reduced pressure is 1.15 clear paste, and hot air drying is pulverized, and adds adjuvant and mixes, and crosses 160 mesh sieves, and by the conventional method film-making, hot air drying sieves, and packing and outer package obtain the tablet product.
Two, clinical drug trial
Clinical data:
Select internal injury cerebral hemorrhage and soft tissue internal injury blood stasis patient 76 examples in the 48h of morbidity back, major part is to receive the outside internal injuries such as head, breast abdominal part and extremity of hitting, and does not have stupor; Liver,spleen,kidney does not have pathological changes; There is part to carry out CT examination and confirms 18～78 years old age, average 46.1 years old; Amount of bleeding 12～60CC, average 28.5CC.
Therapeutic Method:
Adopt the present invention to prepare oral liquid, tablet, granule, capsule and the powder of embodiment, clothes were 3 times in for oral administration day.Divide respectively with 15d, 30d and 60d treatment, after finishing the course of treatment, CT observes blood stasis absorbing state, and total effective rate is 90.6%.
Conclusion:
For many years. Chinese herbal treatment internal injury cerebral hemorrhage of the present invention on probation and soft tissue internal injury blood stasis medicine; Application of treatment internal injury patients with cerebral hemorrhage 26 example and soft tissue internal injury patient 50 examples; See that from therapeutic outcome Radix abutili indici of the present invention, Lignum Sappan, mullein mightbrier leaf are the medicine of vessel softening, dredge the meridian passage and blood circulation promoting and blood stasis dispelling, ability vessel softening, dredge the meridian passage and blood circulation promoting and blood stasis dispelling; Absorption of hematoma is very fast; Pain relieving and improve the effect of ED helps microcirculation improvement, promotes internal injury cerebral hemorrhage and the healing of soft tissue internal injury.
The application test example
Embodiment 1
Chen, the male, 46 years old, on June 3rd, 2008 got into an accident, chest soft tissue internal injury, the pain blood stasis, local purple black obviously, with the conventional treatment by Chinese herbs commentaries on classics of not getting better in 12 days, the pain increased on the contrary.Rose June 16 and take powder product of the present invention, three times on the one for oral administration, taking a turn for the better appears after 3 days in each bag, reduces pain, and swollen rising also begins to subdue.Take 10 days pain more continuously and eliminate basically, 15 days complete.
Embodiment 2
Multitude, women, 53 years old; On October 21st, 20011 caused damaging cerebral hemorrhage because of the brain internal injury that slips, and during intracerebral hemorrhage 21CC, caused brain local blood circulation obstacle; Cause the ACI symptom, aphasia, adopt intravenously administrable, treat and sickly do not have an improvement in two months the doctor.Take oral solutions product of the present invention, three times on the one for oral administration, each bag is taken appearance improvement after the 8th day, can sound the 22nd day recovery linguistic competence.Took continuously two months after the X ray examination, cerebral hemorrhage is eliminated again.
Embodiment 3
Huang, the male, 35 years old, on May 5th, 2006 was caused brain and internal injury of chest because of fighting, cause that brain is hemorrhage, and intracerebral hemorrhage 60CC causes chest pain, inside and outside blood stasis simultaneously.Cause brain local blood circulation obstacle, cause ACI, aphasia symptom, brain pain.Take granule product of the present invention, three times on the one for oral administration, each bag.After taking the 3rd day, chest pain takes a turn for the better; Can sound after the 10th day, internal injury of chest pain is almost recovered; Recover the linguistic competence after the 16th day; After taking two months continuously, through the X ray examination, the hemorrhage elimination of brain, symptomatology recovery from illness.
Embodiment 4
Deep so-and-so, the women, 22 years old, on March 16th, 2010 was caused shank and waist internal injury pain, inside and outside blood stasis because of traffic accident.Cause disturbance of blood circulation.Take capsule product of the present invention two days later, three times on the one for oral administration, each 5.After taking the 4th day, affected part pain takes a turn for the better; After taking the 12nd day, affected part pain is eliminated; After taking one month continuously, through the X ray examination, the symptomatology recovery from illness.
Claims (6)
1. the medicine of Chinese herbal treatment soft tissue internal injury blood stasis and cerebral hemorrhage is characterized in that: main former medicine component and proportioning parts by weight: Radix abutili indici 10-20 part, Lignum Sappan 6-15 part and mullein mightbrier leaf 10-20 part.
2. the medicine of Chinese herbal treatment soft tissue internal injury blood stasis according to claim 1 and cerebral hemorrhage is characterized in that: described former medicine component and proportioning parts by weight are: Radix abutili indici 16-18 part, Lignum Sappan 8-10 part and mullein mightbrier leaf 15-16 part.
3. the method for preparing of the medicine of Chinese herbal treatment soft tissue internal injury blood stasis according to claim 1 and 2 and cerebral hemorrhage; It is characterized in that: carry or/and pure extracting method extracts the Chinese herbal medicine active ingredient with water, be prepared into oral liquid, tablet, granule, capsule and powder.
4. the method for preparing of the medicine of Chinese herbal treatment soft tissue internal injury blood stasis according to claim 3 and cerebral hemorrhage, it is characterized in that: the method for preparing of described oral liquid comprises: raw material Chinese herbal medicine Radix abutili indici, Lignum Sappan and mullein mightbrier leaf are screened respectively, added 8-12 water doubly by the total umber raw material of formulation weight; The control temperature was boiled 1-2 hour for 75-90 ℃, filtered, and filtering residue adds 6-8 water doubly once more and boiled again 1-2 hour at temperature 75-90 ℃; Filter; Merge extractive liquid,, being evaporated to relative density at temperature 60-78 ℃ is 1.05-1.10, by the conventional method batching; Bottling, dress box and vanning obtain the oral liquid product; Perhaps concentrating under reduced pressure is obtained the clear paste that relative density is 1.15-1.25, add Chinese herbal medicine 10-20 pure water dilution doubly, by the conventional method batching, antibacterial, bottling, dress box and vanning obtain the oral liquid product.
5. the method for preparing of the medicine of Chinese herbal treatment soft tissue internal injury blood stasis according to claim 3 and cerebral hemorrhage; It is characterized in that: the method for preparing of described powder or capsule comprises: raw material Chinese herbal medicine Radix abutili indici, Lignum Sappan and mullein mightbrier leaf are screened respectively; Add 8-12 water doubly by the total umber raw material of formulation weight; Boiled 1-2.5 hour at temperature 75-90 ℃, cross and filter water cooking liquid; Filtering residue adds total raw material 5-10 55-70% ethanol water doubly again, temperature 50-60 ℃ alcohol extraction 1-2 hour, filter, resulting alcohol extract uses 50-60 ℃ of concentrating under reduced pressure to obtain relative density to be 1.05-1.15 extractum; Extractum is added in the water cooking liquid, obtain the clear paste that relative density is 1.15-1.25 at 60-85 ℃ of concentrating under reduced pressure, hot air drying is pulverized, and adds adjuvant and mixes, sieve, and packing, dress box and vanning obtain powder or capsule product; Perhaps raw material Chinese herbal medicine Radix abutili indici, Lignum Sappan and mullein mightbrier leaf are screened respectively, hot air drying is pulverized, sieve, and packing, dress box and vanning obtain powder or capsule product.
6. according to the method for preparing of the medicine of claim 3 or 5 described Chinese herbal treatment soft tissue internal injury blood stasis and cerebral hemorrhage; It is characterized in that: described powder or capsule product add the adjuvant mix homogeneously by conventional method; Sieve; Pelletize or film-making, hot air drying, packing and outer package obtain granule or tablet product.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103041292A (en) * | 2012-11-29 | 2013-04-17 | 宁国市中医肿瘤医院 | Traditional Chinese medicine for treating apoplexy |
| WO2014158671A1 (en) * | 2013-03-14 | 2014-10-02 | Avon Products, Inc | Abutilon indicum extracts and methods of use |
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| CN1151822C (en) * | 2001-09-26 | 2004-06-02 | 米长忠 | Liquid medicine for treating traumatic injury |
| CN1332689C (en) * | 2002-09-01 | 2007-08-22 | 吴秋菊 | Medicine composition for treating traumatic injury |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1151822C (en) * | 2001-09-26 | 2004-06-02 | 米长忠 | Liquid medicine for treating traumatic injury |
| CN1332689C (en) * | 2002-09-01 | 2007-08-22 | 吴秋菊 | Medicine composition for treating traumatic injury |
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| 周德荣: "活血化瘀法治疗脑出血急性期临床进展", 《河北中医》, vol. 27, no. 4, 30 April 2005 (2005-04-30), pages 317 - 320 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103041292A (en) * | 2012-11-29 | 2013-04-17 | 宁国市中医肿瘤医院 | Traditional Chinese medicine for treating apoplexy |
| CN103041292B (en) * | 2012-11-29 | 2014-04-09 | 宁国市中医肿瘤医院 | Traditional Chinese medicine for treating apoplexy |
| WO2014158671A1 (en) * | 2013-03-14 | 2014-10-02 | Avon Products, Inc | Abutilon indicum extracts and methods of use |
| US9757327B2 (en) | 2013-03-14 | 2017-09-12 | Avon Products, Inc. | Abutilon indicum extracts and methods of use |
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