CN1403147A - Medicines composition for raising body's immunity and its prepn - Google Patents
Medicines composition for raising body's immunity and its prepn Download PDFInfo
- Publication number
- CN1403147A CN1403147A CN02146571A CN02146571A CN1403147A CN 1403147 A CN1403147 A CN 1403147A CN 02146571 A CN02146571 A CN 02146571A CN 02146571 A CN02146571 A CN 02146571A CN 1403147 A CN1403147 A CN 1403147A
- Authority
- CN
- China
- Prior art keywords
- parts
- immune function
- fried
- wt
- pharmaceutical composition
- Prior art date
Links
- 239000003814 drug Substances 0 abstract title 6
- 239000000203 mixtures Substances 0 abstract title 3
- 238000010010 raising Methods 0 abstract title 3
- 230000036039 immunity Effects 0 abstract title 2
- 229940079593 drugs Drugs 0 abstract 5
- 206010039491 Sarcoma Diseases 0 abstract 2
- 230000002401 inhibitory effects Effects 0 abstract 2
- 229940107666 ASTRAGALUS ROOT Drugs 0 abstract 1
- 229960004397 Cyclophosphamide Drugs 0 abstract 1
- CMSMOCZEIVJLDB-UHFFFAOYSA-N Cyclophosphamide Chemical compound data:image/svg+xml;base64,<?xml version='1.0' encoding='iso-8859-1'?>
<svg version='1.1' baseProfile='full'
              xmlns='http://www.w3.org/2000/svg'
                      xmlns:rdkit='http://www.rdkit.org/xml'
                      xmlns:xlink='http://www.w3.org/1999/xlink'
                  xml:space='preserve'
width='300px' height='300px' >
<!-- END OF HEADER -->
<rect style='opacity:1.0;fill:#FFFFFF;stroke:none' width='300' height='300' x='0' y='0'> </rect>
<path class='bond-0' d='M 259.66,224.895 246.428,211.255' style='fill:none;fill-rule:evenodd;stroke:#00CC00;stroke-width:2px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-0' d='M 246.428,211.255 233.196,197.615' style='fill:none;fill-rule:evenodd;stroke:#000000;stroke-width:2px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-1' d='M 233.196,197.615 185.192,209.701' style='fill:none;fill-rule:evenodd;stroke:#000000;stroke-width:2px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-2' d='M 185.192,209.701 171.533,195.622' style='fill:none;fill-rule:evenodd;stroke:#000000;stroke-width:2px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-2' d='M 171.533,195.622 157.875,181.542' style='fill:none;fill-rule:evenodd;stroke:#0000FF;stroke-width:2px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-3' d='M 153.069,165.921 158.664,146.238' style='fill:none;fill-rule:evenodd;stroke:#0000FF;stroke-width:2px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-3' d='M 158.664,146.238 164.259,126.555' style='fill:none;fill-rule:evenodd;stroke:#000000;stroke-width:2px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-6' d='M 143.573,175.971 126.449,180.282' style='fill:none;fill-rule:evenodd;stroke:#0000FF;stroke-width:2px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-6' d='M 126.449,180.282 109.326,184.593' style='fill:none;fill-rule:evenodd;stroke:#FF7F00;stroke-width:2px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-4' d='M 164.259,126.555 212.263,114.47' style='fill:none;fill-rule:evenodd;stroke:#000000;stroke-width:2px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-5' d='M 212.263,114.47 217.858,94.7875' style='fill:none;fill-rule:evenodd;stroke:#000000;stroke-width:2px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-5' d='M 217.858,94.7875 223.454,75.1049' style='fill:none;fill-rule:evenodd;stroke:#00CC00;stroke-width:2px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-7' d='M 101.898,196.53 108.321,210.868' style='fill:none;fill-rule:evenodd;stroke:#FF7F00;stroke-width:2px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-7' d='M 108.321,210.868 114.744,225.206' style='fill:none;fill-rule:evenodd;stroke:#FF0000;stroke-width:2px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-7' d='M 110.933,192.483 117.356,206.821' style='fill:none;fill-rule:evenodd;stroke:#FF7F00;stroke-width:2px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-7' d='M 117.356,206.821 123.779,221.158' style='fill:none;fill-rule:evenodd;stroke:#FF0000;stroke-width:2px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-8' d='M 96.1133,190.734 85.0144,198.258' style='fill:none;fill-rule:evenodd;stroke:#FF7F00;stroke-width:2px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-8' d='M 85.0144,198.258 73.9155,205.781' style='fill:none;fill-rule:evenodd;stroke:#0000FF;stroke-width:2px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-13' d='M 102.124,178.006 100.937,161.57' style='fill:none;fill-rule:evenodd;stroke:#FF7F00;stroke-width:2px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-13' d='M 100.937,161.57 99.7494,145.133' style='fill:none;fill-rule:evenodd;stroke:#FF0000;stroke-width:2px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-9' d='M 47.4421,207.096 32.3223,199.765' style='fill:none;fill-rule:evenodd;stroke:#0000FF;stroke-width:2px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-9' d='M 32.3223,199.765 17.2024,192.433' style='fill:none;fill-rule:evenodd;stroke:#000000;stroke-width:2px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-10' d='M 17.2024,192.433 13.6364,143.06' style='fill:none;fill-rule:evenodd;stroke:#000000;stroke-width:2px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-11' d='M 13.6364,143.06 54.6119,115.285' style='fill:none;fill-rule:evenodd;stroke:#000000;stroke-width:2px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-12' d='M 54.6119,115.285 73.0299,124.216' style='fill:none;fill-rule:evenodd;stroke:#000000;stroke-width:2px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-12' d='M 73.0299,124.216 91.4479,133.147' style='fill:none;fill-rule:evenodd;stroke:#FF0000;stroke-width:2px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<text x='258.315' y='241.396' style='font-size:16px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#00CC00' ><tspan>Cl</tspan></text>
<text x='143.573' y='182.421' style='font-size:16px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#0000FF' ><tspan>N</tspan></text>
<text x='216.449' y='75.1049' style='font-size:16px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#00CC00' ><tspan>Cl</tspan></text>
<text x='96.1133' y='194.507' style='font-size:16px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#FF7F00' ><tspan>P</tspan></text>
<text x='115.252' y='239.683' style='font-size:16px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#FF0000' ><tspan>O</tspan></text>
<text x='47.4421' y='222.282' style='font-size:16px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#0000FF' ><tspan>NH</tspan></text>
<text x='91.4479' y='145.133' style='font-size:16px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#FF0000' ><tspan>O</tspan></text>
</svg>
 data:image/svg+xml;base64,<?xml version='1.0' encoding='iso-8859-1'?>
<svg version='1.1' baseProfile='full'
              xmlns='http://www.w3.org/2000/svg'
                      xmlns:rdkit='http://www.rdkit.org/xml'
                      xmlns:xlink='http://www.w3.org/1999/xlink'
                  xml:space='preserve'
width='85px' height='85px' >
<!-- END OF HEADER -->
<rect style='opacity:1.0;fill:#FFFFFF;stroke:none' width='85' height='85' x='0' y='0'> </rect>
<path class='bond-0' d='M 73.0705,63.2203 69.3213,59.3557' style='fill:none;fill-rule:evenodd;stroke:#00CC00;stroke-width:2px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-0' d='M 69.3213,59.3557 65.5722,55.491' style='fill:none;fill-rule:evenodd;stroke:#000000;stroke-width:2px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-1' d='M 65.5722,55.491 51.971,58.9153' style='fill:none;fill-rule:evenodd;stroke:#000000;stroke-width:2px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-2' d='M 51.971,58.9153 48.1011,54.9261' style='fill:none;fill-rule:evenodd;stroke:#000000;stroke-width:2px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-2' d='M 48.1011,54.9261 44.2311,50.9369' style='fill:none;fill-rule:evenodd;stroke:#0000FF;stroke-width:2px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-3' d='M 42.8695,46.5108 44.4548,40.9341' style='fill:none;fill-rule:evenodd;stroke:#0000FF;stroke-width:2px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-3' d='M 44.4548,40.9341 46.0401,35.3574' style='fill:none;fill-rule:evenodd;stroke:#000000;stroke-width:2px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-6' d='M 40.1789,49.3585 35.3273,50.58' style='fill:none;fill-rule:evenodd;stroke:#0000FF;stroke-width:2px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-6' d='M 35.3273,50.58 30.4756,51.8014' style='fill:none;fill-rule:evenodd;stroke:#FF7F00;stroke-width:2px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-4' d='M 46.0401,35.3574 59.6413,31.9332' style='fill:none;fill-rule:evenodd;stroke:#000000;stroke-width:2px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-5' d='M 59.6413,31.9332 61.2266,26.3565' style='fill:none;fill-rule:evenodd;stroke:#000000;stroke-width:2px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-5' d='M 61.2266,26.3565 62.8119,20.7797' style='fill:none;fill-rule:evenodd;stroke:#00CC00;stroke-width:2px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-7' d='M 28.3711,55.1836 30.1909,59.246' style='fill:none;fill-rule:evenodd;stroke:#FF7F00;stroke-width:2px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-7' d='M 30.1909,59.246 32.0107,63.3083' style='fill:none;fill-rule:evenodd;stroke:#FF0000;stroke-width:2px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-7' d='M 30.931,54.0368 32.7509,58.0992' style='fill:none;fill-rule:evenodd;stroke:#FF7F00;stroke-width:2px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-7' d='M 32.7509,58.0992 34.5707,62.1615' style='fill:none;fill-rule:evenodd;stroke:#FF0000;stroke-width:2px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-8' d='M 26.7321,53.5414 23.5874,55.673' style='fill:none;fill-rule:evenodd;stroke:#FF7F00;stroke-width:2px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-8' d='M 23.5874,55.673 20.4427,57.8046' style='fill:none;fill-rule:evenodd;stroke:#0000FF;stroke-width:2px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-13' d='M 28.435,49.935 28.0987,45.2781' style='fill:none;fill-rule:evenodd;stroke:#FF7F00;stroke-width:2px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-13' d='M 28.0987,45.2781 27.7623,40.6211' style='fill:none;fill-rule:evenodd;stroke:#FF0000;stroke-width:2px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-9' d='M 12.9419,58.1773 8.65797,56.1' style='fill:none;fill-rule:evenodd;stroke:#0000FF;stroke-width:2px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-9' d='M 8.65797,56.1 4.37402,54.0227' style='fill:none;fill-rule:evenodd;stroke:#000000;stroke-width:2px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-10' d='M 4.37402,54.0227 3.36364,40.0336' style='fill:none;fill-rule:evenodd;stroke:#000000;stroke-width:2px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-11' d='M 3.36364,40.0336 14.9734,32.164' style='fill:none;fill-rule:evenodd;stroke:#000000;stroke-width:2px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-12' d='M 14.9734,32.164 20.1918,34.6944' style='fill:none;fill-rule:evenodd;stroke:#000000;stroke-width:2px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-12' d='M 20.1918,34.6944 25.4102,37.2249' style='fill:none;fill-rule:evenodd;stroke:#FF0000;stroke-width:2px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<text x='72.6891' y='67.8955' style='font-size:4px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#00CC00' ><tspan>Cl</tspan></text>
<text x='40.1789' y='51.186' style='font-size:4px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#0000FF' ><tspan>N</tspan></text>
<text x='60.8273' y='20.7797' style='font-size:4px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#00CC00' ><tspan>Cl</tspan></text>
<text x='26.7321' y='54.6102' style='font-size:4px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#FF7F00' ><tspan>P</tspan></text>
<text x='32.1546' y='67.4101' style='font-size:4px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#FF0000' ><tspan>O</tspan></text>
<text x='12.9419' y='62.4798' style='font-size:4px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#0000FF' ><tspan>NH</tspan></text>
<text x='25.4102' y='40.6211' style='font-size:4px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#FF0000' ><tspan>O</tspan></text>
</svg>
 ClCCN(CCCl)P1(=O)NCCCO1 CMSMOCZEIVJLDB-UHFFFAOYSA-N 0 abstract 1
- 241000222336 Ganoderma Species 0 abstract 1
- 240000006509 Gynostemma pentaphyllum Species 0 abstract 1
- 235000002956 Gynostemma pentaphyllum Nutrition 0 abstract 1
- 210000003734 Kidney Anatomy 0 abstract 1
- 241000735234 Ligustrum Species 0 abstract 1
- 240000004678 Panax pseudoginseng Species 0 abstract 1
- 235000003140 Panax quinquefolius Nutrition 0 abstract 1
- 210000000952 Spleen Anatomy 0 abstract 1
- 239000002775 capsule Substances 0 abstract 1
- 230000000973 chemotherapeutic Effects 0 abstract 1
- 239000002131 composite material Substances 0 abstract 1
- 230000000694 effects Effects 0 abstract 1
- 235000008434 ginseng Nutrition 0 abstract 1
- 235000005035 ginseng Nutrition 0 abstract 1
- 230000012010 growth Effects 0 abstract 1
- 239000000463 materials Substances 0 abstract 1
- 230000000144 pharmacologic effect Effects 0 abstract 1
- 239000010911 seed Substances 0 abstract 1
- 238000005728 strengthening Methods 0 abstract 1
- 230000004083 survival Effects 0 abstract 1
Abstract
The present invention provides one medicine composition for raising body's immunity and invigorating spleen and kidney based on the Chinese medicine theory of strengthening body's resistance to eliminate evil. The medicine composition has 15 kinds of Chinese medicinal materials including astragalus root, privet seed, ginseng, glossy ganoderma, gynostemma pentaphylla, etc. The pharmacological testshows that the composite medicine capsule has obvious effects of inhibiting the growth of mouse's S180 sarcoma, prolonging the survival days of the mouse and raising the inhibition of chemotherapeutic medicine cyclophosphamide to mouse's S180 sarcoma.
Description
技术领域 FIELD
本发明涉及到一种提高机体免疫功能的药物组合物，属于中草药制剂技术领域，尤其适用于临床上治疗肿瘤、肝炎、肝硬化等脾肾亏虚，瘀毒内结症所致形体消瘦、体倦乏力、脘腹胀满等症。 The present invention relates to an improved immune function in a pharmaceutical composition, belongs to the technical field of herbal preparations, especially for the clinical treatment of cancer, hepatitis, cirrhosis, spleen and kidney deficiency, blood stasis within the knot disease caused by toxic body weight loss, body tired fatigue, abdominal distention embolism.
背景技术 Background technique
肿瘤、肝炎、肝硬化等脾肾亏虚，瘀毒内结症所致形体消瘦、体倦乏力、脘腹胀满等症属祖国医学的“虚损”范畴。 Cancer, hepatitis, cirrhosis, spleen and kidney deficiency, within Ecchymosis knot disease caused by emaciation, lassitude, abdominal distention sickness medicine is the motherland of "wasting" category. 目前，治疗免疫低下的中药制剂，如潞党参膏滋(补中益气，健脾益肺)、云芝糖肽胶囊(补益精气，健脾养心)、十味扶正颗粒(补益气血，温阳健脾)、参芪扶正注射液(益气扶正)、参一胶囊(培元固本，补益气血)，它们多偏向于补，过于片面。 Currently, the treatment of immunocompromised Chinese medicine, such as Lu Codonopsis Gaozi (deficiency of spleen Yifei), PSP capsules (tonic gas, nourishing the heart and spleen), Shiweifuzheng particles (blood tonic , spleen yang), SFI (Qi righting), a reference capsules (Pei-yuan consolidate, blood tonic), they tend to make multiple, too one-sided. 本发明认为免疫功能低下疾病所出现形体消瘦、体倦乏力、神疲懒言、纳减食少、脘腹胀满等症乃脾肾亏虚，瘀毒内结而致，为本虚标实之证，故以健脾补肾，化瘀解毒为治则，从标本兼治入手，可明显提高体液与细胞免疫机能，从而增强抗病能力，并可增强体力。 The inventors believe that the disease occurs in immunocompromised emaciation, lassitude, Shenpi lazy words, reduced sodium food, abdominal distention embolism is the spleen and kidney deficiency, may cause the junction Ecchymosis, oriented vacuity card, so as to spleen and kidney, stasis for the rule is, starting from treating the symptoms, can significantly improve humoral and cellular immune function, to enhance disease resistance, and can enhance strength.
发明内容 SUMMARY
本发明以中医扶正祛邪理论提供一种以提高机体免疫功能，健脾补肾的药物组合物，达到标本兼治。 The present invention provides a kind of traditional Chinese medicine theory Fuzhengquxie improve immune function, spleen and kidney of a pharmaceutical composition, to tackling the problem.
本发明的技术方案是这样实现的：这种提高机体免疫功能的药物组合物，其组成比例(重量/重量)包括黄芪130-390份、女贞子105-315份、人参39-117份、灵芝40-120份、莪术79-327份、绞股蓝157-473份、白术(炒)40-120份、茯苓40-120份、冬虫夏草5-15份、徐长卿79-237份、土鳖虫40-120份、三七13-39份、白花蛇舌草79-237份、半枝莲79-237份、神曲(炒)25-75份。 Aspect of the present invention is achieved: The pharmaceutical composition of this improved immune function, its composition ratio (wt / wt) comprises 130-390 parts astragalus, 105-315 parts of Ligustrum lucidum, ginseng 39-117 parts, 40-120 parts of Ganoderma lucidum, Curcuma 79-327 parts, parts of Gynostemma 157-473, Atractylodes (fried) 40-120 parts, Poria 40-120 parts, Cordyceps 5-15 parts, parts of Cynanchum 79-237, 40-120 Eupolyphaga parts, March 13-39 parts, parts diffusa 79-237, 79-237 parts barbata, Shinkyoku (fried) 25-75 parts.
所述的提高机体免疫功能的药物组合物，其组成比例(重量/重量)包括黄芪260份、女贞子210份、人参78份、灵芝80份、莪术158份、绞股蓝315份、白术(炒)80份、茯苓80份、冬虫夏草10份、徐长卿158份、土鳖虫80份、三七26份、白花蛇舌草158份、半枝莲158份、神曲(炒)50份。 Improve immune function of the pharmaceutical composition, which composition ratio (wt / wt) comprising 260 parts of astragalus, 210 parts of Ligustrum lucidum, ginseng 78 parts, 80 parts of Ganoderma lucidum, Curcuma 158 parts, 315 parts of Gynostemma, Atractylodes (fried ) 80 parts, Poria 80 parts, 10 parts of Cordyceps sinensis, Cynanchum 158 parts, 80 parts Eupolyphaga notoginseng 26 parts, 158 parts diffusa, barbata 158 parts Shinkyoku (fry) 50 parts.
所述的提高机体免疫功能的药物组合物，其组成还可包括党参、龟板胶、补骨脂、三棱、麦冬、枸杞、当归、何首乌、熟地、干姜、桃仁、生地黄、知母、山楂、麦芽、杜仲其中一种或几种。 Improve immune function of the pharmaceutical composition, which composition may further comprise Codonopsis, turtle shell, psoralen, triangular, Radix, wolfberry, angelica, Polygonum multiflorum, Rehmannia, ginger, peach, Rehmanniae, Anemarrhena , hawthorn, malt, wherein one or more of eucommia.
上述提高机体免疫功能的药物组合物的制备方法包括：(1)、人参78份、冬虫夏草10份、三七26份分别粉碎成细粉，过筛备用；(2)、黄芪260份、女贞子210份、灵芝80份、莪术158份、绞股蓝315份、白术(炒)80份、茯苓80份、徐长即158份、土鳖虫80份、白花蛇舌草158份、半枝莲158份、神曲(炒)50份加水煎煮两次，第一次2小时，第二次1小时，合并煎煮液过滤，滤液浓缩，干燥，粉碎成细粉，与步骤(1)粉末配研，过筛混匀，装胶囊。 Improve immune function of the above-described method for the preparation of a pharmaceutical composition comprising: (1), ginseng 78 parts, 10 parts of Cordyceps, Panax parts 26 are crushed into fine powder, sift; (2), 260 parts of astragalus, privet sub 210 parts, 80 parts of Ganoderma lucidum, Curcuma 158 parts, 315 parts of Gynostemma, Atractylodes (fried) 80 parts, 80 parts of Poria, i.e., 158 parts of long Xu, 80 parts Eupolyphaga, diffusa 158 parts, 158 parts of Scutellaria barbata , Shinkyoku (fry) 50 parts of boiling water twice, the first time 2 hours, the second time for 1 hour decoction combined filtrate was concentrated, dried, crushed into powder, and the step (1) with powder RESEARCH, sieved mixing, encapsulating.
上述提高机体免疫功能的药物组合物亦可以用于临床上制备片剂、冲剂、散剂等口服制剂的基本原料。 Improve immune function above pharmaceutical compositions can also be used for basic raw materials of tablets, granules, powders and the like of oral formulations clinically.
经河北医科大学中医学院药理试验研究表明，本发明的药物组合物胶囊(商品名称为华奇胶囊或参灵蓝胶囊)对小鼠S180肉瘤的生长有明显抑制作用，可延长艾氏腹水瘤小鼠生存天数，与化疗药物环磷酰胺合用对小鼠S180肉瘤的抑制作用有明显增效作用，可使环磷酰胺所致免疫功能低下的小鼠血清溶血素明显升高，脾淋巴细胞转化率明显增加，对环磷酰胺致小鼠白细胞减少有逆转作用，对环磷酰胺致小鼠进食量减少有增加作用。 Experimental studies by Hebei Medical University Medical Pharmacology show, the pharmaceutical compositions of the present invention, the capsule (trade name Buchwald capsule or capsule reference Ling blue) significantly inhibited the growth of mouse S180 sarcoma, Ehrlich ascites tumor extended small the survival number of days, in combination with chemotherapy cyclophosphamide significantly synergistic inhibition S180 sarcoma in mice, induced by cyclophosphamide can immunocompromised mouse serum hemolysin significantly increased spleen lymphocyte transformation rate increased significantly, on leukopenia induced by cyclophosphamide in mice has a reverse effect on food intake in mice induced by cyclophosphamide increased reduction effect.
小鼠急性毒性试验表明，本发明胶囊临床用量为6g/日，小鼠口服最大耐受量为20.0g/kg，相当于成人临床用量的232.6倍，动物无明显异常及死亡。 Acute toxicity test in mice showed clinical dose capsules of the present invention is 6g / day, the mice orally maximum tolerated dose of 20.0g / kg, equivalent to 232.6-fold clinical dosage for adults, the animals showed no abnormalities and death. 长期毒性试验表明：本发明对大鼠一般状况、体重、血象等生化指标及主要脏器系数均无明显影响，说明本发明无明显毒性反应。 Long-term toxicity tests show that: no significant effect on the general condition of the present invention in rats, body weight, blood biochemical indexes and organ index, indicating no significant toxicity to the present invention. 见附件。 see attached.
具体实施方式 Detailed ways
下面结合本发明药物组合的实例，说明本发明的具体实施方式。 Examples of pharmaceutical compositions below with the present invention, illustrate specific embodiments of the present invention.
上述实施例的制备方法制成的混合物可以用于临床上制备片剂、冲剂、散剂等口服制剂的基本原料。 Mixture into a preparation method of the above embodiments may be used for basic raw materials of tablets, granules, powders and the like of oral formulations clinically.
本发明药物组合物以黄芪、女贞子为君，以人参、灵芝、莪术、绞股蓝为臣药，白术、茯苓、冬虫夏草、徐长卿、土鳖虫、三七、白花蛇舌草共为佐药，半枝莲、神曲为使，对于免疫功能低下造成的肿瘤、肝炎、肝硬化等均可作为治疗辅助药物应用，可增强体力，抵御外邪，使机体早日康复。 The pharmaceutical compositions of the present invention, astragalus, King Ligustrum lucidum, ginseng, Ganoderma lucidum, Curcuma, Gynostemma Chen medicine, Poria, Cordyceps sinensis, Cynanchum, Eupolyphaga, Panax, diffusa total of adjuvant, half Chi Lin, as the Divine Comedy, for tumor immune dysfunction caused by hepatitis, cirrhosis and other applications can be used as an adjunct to treatment, can build up their strength, resist evils, so that the body a speedy recovery.
Claims (4)
1.一种提高机体免疫功能的药物组合物，其组成比例(重量/重量)包括黄芪130-390份、女贞子105-315份、人参39-117份、灵芝40-120份、莪术79-327份、绞股蓝157-473份、白术(炒)40-120份、茯苓40-120份、冬虫夏草5-15份、徐长卿79-237份、土鳖虫40-120份、三七13-39份、白花蛇舌草79-237份、半枝莲79-237份、神曲(炒)25-75份。 1. A method of increasing the immune function of the pharmaceutical composition, which composition ratio (wt / wt) comprises 130-390 parts astragalus, Ligustrum lucidum parts 105-315, 39-117 parts of ginseng, Ganoderma 40-120 parts, Curcuma 79 -327 parts of Gynostemma 157-473 parts of Atractylodes (fried) 40-120 parts, Poria 40-120 parts, 5-15 parts of Cordyceps, Cynanchum 79-237 parts, Eupolyphaga 40-120 parts, 13-39 parts thirty-seven , 79-237 parts diffusa, barbata 79-237 parts Shinkyoku (fried) 25-75 parts.
2.根据权利要求1所述的提高机体免疫功能的药物组合物，其组成比例(重量/重量)包括黄芪260份、女贞子210份、人参78份、灵芝80份、莪术158份、绞股蓝315份、白术(炒)80份、茯苓80份、冬虫夏草10份、徐长卿158份、土鳖虫80份、三七26份、白花蛇舌草158份、半枝莲158份、神曲(炒)50份。 Improve immune function The pharmaceutical composition according to claim 1, which composition ratio (wt / wt) comprising 260 parts of astragalus, 210 parts of Ligustrum lucidum, ginseng 78 parts, 80 parts of Ganoderma lucidum, Curcuma 158 parts, Gynostemma 315 parts of Atractylodes (fried) 80 parts, Poria 80 parts, 10 parts of Cordyceps sinensis, Cynanchum 158 parts, 80 parts Eupolyphaga notoginseng 26 parts, 158 parts diffusa, barbata 158 parts Shinkyoku (fry) 50 copies.
3.根据权利要求1所述的提高机体免疫功能的药物组合物，其组成还可包括党参、龟板胶、补骨脂、三棱、麦冬、枸杞、当归、何首乌、熟地、干姜、桃仁、生地黄、知母、山楂、麦芽、杜仲其中一种或几种。 The improved immune function pharmaceutical composition according to claim 1, which composition may further comprise Codonopsis, turtle shell, psoralen, triangular, Radix, wolfberry, angelica, Polygonum multiflorum, Rehmannia, ginger, walnuts , Rehmanniae, Anemarrhena, hawthorn, malt, wherein one or more of eucommia.
4.上述提高机体免疫功能的药物组合物的制备方法包括：(1)、人参78份、冬虫夏草10份、三七26份分别粉碎成细粉，过筛备用；(2)、黄芪260份、女贞子210份、灵芝80份、莪术158份、绞股蓝315份、白术(炒)80份、茯苓80份、徐长即158份、土鳖虫80份、白花蛇舌草158份、半枝莲158份、神曲(炒)50份加水煎煮两次，第一次2小时，第二次1小时，合并煎煮液过滤，滤液浓缩，干燥，粉碎成细粉，与步骤(1)粉末配研，过筛混匀，装胶囊。 4. The improved immune function preparation of a pharmaceutical composition comprising: (1), ginseng 78 parts, 10 parts of Cordyceps, Panax parts 26 are crushed into fine powder, sift; (2), 260 parts of astragalus, Ligustrum lucidum 210 parts, 80 parts of Ganoderma lucidum, Curcuma 158 parts, 315 parts of Gynostemma, Atractylodes (fried) 80 parts, 80 parts of Poria, i.e., 158 parts of long Xu, Eupolyphaga 80 parts, 158 parts diffusa, Scutellaria barbata 158 parts Shinkyoku (fry) 50 parts of boiling water twice, the first time 2 hours, the second time for 1 hour decoction combined filtrate was concentrated, dried, crushed into powder, and the step (1) with the powder research, sifting mixing, encapsulating.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB021465711A CN1188158C (en) | 2002-10-24 | 2002-10-24 | Medicines composition for raising body's immunity and its prepn |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB021465711A CN1188158C (en) | 2002-10-24 | 2002-10-24 | Medicines composition for raising body's immunity and its prepn |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1403147A true CN1403147A (en) | 2003-03-19 |
| CN1188158C CN1188158C (en) | 2005-02-09 |
Family
ID=4751111
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB021465711A CN1188158C (en) | 2002-10-24 | 2002-10-24 | Medicines composition for raising body's immunity and its prepn |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1188158C (en) |
Cited By (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101773548A (en) * | 2010-03-25 | 2010-07-14 | 云南金泰得三七产业股份有限公司 | Pharmaceutical composition for improving immunity |
| CN101455391B (en) | 2008-11-27 | 2012-04-25 | 成都润馨堂药业有限公司 | Nutrient health-care food capable of immunomodulating and preparation method thereof |
| CN101607058B (en) | 2008-06-20 | 2012-06-27 | 河北以岭医药研究院有限公司 | Application of Chinese medicinal composition in preparing medicament for treating chronic nephritis |
| CN101607059B (en) | 2008-06-20 | 2012-06-27 | 河北以岭医药研究院有限公司 | Application of Chinese medicinal composition in preparing medicament for treating and preventing radiation injury |
| CN102526283A (en) * | 2011-11-02 | 2012-07-04 | 宁波海逸生物科技有限公司 | Health-care medicine formula with functions of enhancing immunity, alleviating physical fatigue and resisting tumor |
| CN102772523A (en) * | 2012-08-09 | 2012-11-14 | 谢瑜 | Bitter glossy ganoderma composition for oncotherapy and preparation method of bitter glossy ganoderma composition |
| CN102961497A (en) * | 2012-11-29 | 2013-03-13 | 王吉坤 | Chinese herbal compound prescription used for treating chronic diarrhea |
| CN103405590A (en) * | 2013-08-16 | 2013-11-27 | 山西省中医药研究院 | Traditional Chinese medicine preparation having effect of immunoregulation and preparation method thereof |
| CN103749821A (en) * | 2013-12-31 | 2014-04-30 | 青岛恒波仪器有限公司 | Gynostemma pentaphyllum health-care tea capable of enhancing immunity and preparation method thereof |
| CN103768519A (en) * | 2013-12-25 | 2014-05-07 | 江苏省中医院 | Compound medicine capable of improving anti-tumor curative effect of phosphamide and preparation method thereof |
| CN104013721A (en) * | 2014-05-07 | 2014-09-03 | 娄志 | Kidney-tonifying traditional Chinese medicine |
| CN104107388A (en) * | 2013-04-17 | 2014-10-22 | 天津药物研究院 | Immunity-enhancing and anti-tumor compound traditional Chinese medicine composition, preparation method and application thereof |
| CN104398971A (en) * | 2014-11-04 | 2015-03-11 | 王松华 | Traditional Chinese medicine composition for treating liver cirrhosis, and preparation method and application thereof |
| CN104415132A (en) * | 2013-08-21 | 2015-03-18 | 上海圣赐康生物医药科技有限公司 | Compound formula for preparing soft capsule by pro-liposomes of ganoderma spore and freshwater mussel and preparation method thereof |
| CN104474458A (en) * | 2014-11-24 | 2015-04-01 | 宋海燕 | Traditional Chinese medicine composition |
| CN104547334A (en) * | 2015-01-27 | 2015-04-29 | 邹士东 | Traditional Chinese medicine composition for treating autoimmune hepatitis and preparation method of traditional Chinese medicine composition |
| CN104547606A (en) * | 2014-06-26 | 2015-04-29 | 安徽霍山县药王谷林农科技有限公司 | Dendrobium huoshanense-ginseng-radix astragali preparata health granule for strengthening body resistance |
| CN105535356A (en) * | 2014-11-03 | 2016-05-04 | 谢芳 | Traditional Chinese medicinal ointment and preparation method thereof |
| CN106421665A (en) * | 2016-11-24 | 2017-02-22 | 江苏省中医院 | Application of compound traditional Chinese medicine composition to preparation of human immunity improving drug |
| CN107375896A (en) * | 2017-06-26 | 2017-11-24 | 郑相国 | For suppressing the Chinese patent drug of cancer cell multiplication |
-
2002
- 2002-10-24 CN CNB021465711A patent/CN1188158C/en active IP Right Grant
Cited By (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101607058B (en) | 2008-06-20 | 2012-06-27 | 河北以岭医药研究院有限公司 | Application of Chinese medicinal composition in preparing medicament for treating chronic nephritis |
| CN101607059B (en) | 2008-06-20 | 2012-06-27 | 河北以岭医药研究院有限公司 | Application of Chinese medicinal composition in preparing medicament for treating and preventing radiation injury |
| CN101455391B (en) | 2008-11-27 | 2012-04-25 | 成都润馨堂药业有限公司 | Nutrient health-care food capable of immunomodulating and preparation method thereof |
| CN101773548A (en) * | 2010-03-25 | 2010-07-14 | 云南金泰得三七产业股份有限公司 | Pharmaceutical composition for improving immunity |
| CN101773548B (en) | 2010-03-25 | 2011-12-21 | 云南金泰得三七产业股份有限公司 | A method of enhancing immunity pharmaceutical compositions |
| CN102526283A (en) * | 2011-11-02 | 2012-07-04 | 宁波海逸生物科技有限公司 | Health-care medicine formula with functions of enhancing immunity, alleviating physical fatigue and resisting tumor |
| CN102772523A (en) * | 2012-08-09 | 2012-11-14 | 谢瑜 | Bitter glossy ganoderma composition for oncotherapy and preparation method of bitter glossy ganoderma composition |
| CN102772523B (en) * | 2012-08-09 | 2014-11-19 | 谢瑜 | Bitter glossy ganoderma composition for oncotherapy and preparation method of bitter glossy ganoderma composition |
| CN102961497A (en) * | 2012-11-29 | 2013-03-13 | 王吉坤 | Chinese herbal compound prescription used for treating chronic diarrhea |
| CN102961497B (en) * | 2012-11-29 | 2014-04-02 | 王吉坤 | Chinese herbal compound prescription used for treating chronic diarrhea |
| CN104107388B (en) * | 2013-04-17 | 2017-09-12 | 天津药物研究院 | One kind improves immunity anti-tumor compound Chinese medicine composition and its production and use |
| CN104107388A (en) * | 2013-04-17 | 2014-10-22 | 天津药物研究院 | Immunity-enhancing and anti-tumor compound traditional Chinese medicine composition, preparation method and application thereof |
| CN103405590B (en) * | 2013-08-16 | 2016-01-20 | 山西省中医药研究院 | A kind of Chinese medicine preparation and preparation method with immunoregulation effect |
| CN103405590A (en) * | 2013-08-16 | 2013-11-27 | 山西省中医药研究院 | Traditional Chinese medicine preparation having effect of immunoregulation and preparation method thereof |
| CN104415132A (en) * | 2013-08-21 | 2015-03-18 | 上海圣赐康生物医药科技有限公司 | Compound formula for preparing soft capsule by pro-liposomes of ganoderma spore and freshwater mussel and preparation method thereof |
| CN103768519B (en) * | 2013-12-25 | 2016-08-17 | 江苏省中医院 | A kind of compound medicine improving cyclophosphamide antitumor curative effect and preparation method thereof |
| CN103768519A (en) * | 2013-12-25 | 2014-05-07 | 江苏省中医院 | Compound medicine capable of improving anti-tumor curative effect of phosphamide and preparation method thereof |
| CN103749821A (en) * | 2013-12-31 | 2014-04-30 | 青岛恒波仪器有限公司 | Gynostemma pentaphyllum health-care tea capable of enhancing immunity and preparation method thereof |
| CN103749821B (en) * | 2013-12-31 | 2015-12-09 | 张绪伟 | A kind of gynostemma pentaphylla health-care tea improving immunity and preparation method thereof |
| CN104013721A (en) * | 2014-05-07 | 2014-09-03 | 娄志 | Kidney-tonifying traditional Chinese medicine |
| CN104547606A (en) * | 2014-06-26 | 2015-04-29 | 安徽霍山县药王谷林农科技有限公司 | Dendrobium huoshanense-ginseng-radix astragali preparata health granule for strengthening body resistance |
| CN105535356A (en) * | 2014-11-03 | 2016-05-04 | 谢芳 | Traditional Chinese medicinal ointment and preparation method thereof |
| CN104398971A (en) * | 2014-11-04 | 2015-03-11 | 王松华 | Traditional Chinese medicine composition for treating liver cirrhosis, and preparation method and application thereof |
| CN104474458A (en) * | 2014-11-24 | 2015-04-01 | 宋海燕 | Traditional Chinese medicine composition |
| CN104547334A (en) * | 2015-01-27 | 2015-04-29 | 邹士东 | Traditional Chinese medicine composition for treating autoimmune hepatitis and preparation method of traditional Chinese medicine composition |
| CN106421665A (en) * | 2016-11-24 | 2017-02-22 | 江苏省中医院 | Application of compound traditional Chinese medicine composition to preparation of human immunity improving drug |
| CN106421665B (en) * | 2016-11-24 | 2019-06-18 | 江苏省中医院 | A kind of compound traditional Chinese medicine composite improves the immunity of the human body the application in drug in preparation |
| CN107375896A (en) * | 2017-06-26 | 2017-11-24 | 郑相国 | For suppressing the Chinese patent drug of cancer cell multiplication |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1188158C (en) | 2005-02-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP1594516B9 (en) | Herbal compositions for prostate conditions | |
| Borchers et al. | Complementary medicine: a review of immunomodulatory effects of Chinese herbal medicines | |
| US6455078B1 (en) | Medicinal herbal composition for treating liver diseases and HIV | |
| CN1251756C (en) | Series Chinese medicinal composition for treating liver cancer, esophagus cancer and gastric cancer | |
| CN1044974C (en) | Anti-hepatitis B drugs | |
| CN1124153C (en) | Medicinal composition for restoring cardiac collaterals and its application | |
| CN1216620C (en) | Composite medicine for treating leukemia | |
| CN1330347C (en) | Gongbu ointment | |
| US6911221B2 (en) | Anti-neoplastic drug | |
| CN1951481A (en) | Medicament for treating cerebral thrombosis | |
| US6696094B2 (en) | Herbal pharmaceutical composition for treatment of HIV/AIDS patients | |
| CN101785835B (en) | Traditional Chinese medicine combination and preparation method thereof for chronic enteritis treatment | |
| CN1403149A (en) | Medicines composition for treating chronic heart failure and its prepn | |
| CN1290565C (en) | Medicine for treating digestive disease | |
| CN1899582A (en) | Medicine for treating chronic gastritis and its preparing method | |
| CN1186070C (en) | Medicine composition for treating impotence | |
| CN1062157C (en) | Hepatitis B curing toxin-dissipating pill | |
| CN100353983C (en) | Chinese medicine preparation for reducing sugar | |
| CN101757542B (en) | Traditional Chinese medicine composition for treating colonitis and preparation method | |
| CN1336207A (en) | Life-prolonging tea | |
| CN101342317B (en) | Medicament composition for treating tuberculosis and preparation method thereof | |
| CN102755594A (en) | Traditional Chinese medicine composition for treating acute and chronic hepatitis B and preparation method thereof | |
| EP1707238A1 (en) | Pharmaceuticals of chinese traditional medicine of treating lung cancer and preparation method thereof | |
| CN101327307B (en) | Medicament for treating cancer and preparation method | |
| CN101961102A (en) | Health care product with effect of protecting liver |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| C10 | Request of examination as to substance | ||
| C14 | Granted | ||
| ASS | Succession or assignment of patent right |
Owner name: SHIJIAZHUANG YILING MEDICINE CO., LTD. Free format text: FORMER OWNER: HEBEI YILING MEDICINE INST. CO., LTD. Effective date: 20080516 |
|
| C41 | Transfer of the right of patent application or the patent right |