CN1364468A - Wall breaking and extracting method for Chinese herbal medicine and formulation - Google Patents

Abstract

The present invention relates to the method for extracting effective components in animal and Chinese herbal medicinal material. Pre-treated Chinese herbal medicine material is thrice hot extracted and trice wall breaking pressed to obtain extraction liquid and pressed liquid, which are further reducing concentrated into fluid extract. The technological process is simple, high in the extracting rate of the effective components is Chinese herbal medicinal materials. The product is easy to take and to preserve, has obvious and fast effect. The product has uniform components and contains medicinal fiber good for people's health.

Description

The breaking cellular wall extracting method of Chinese crude drug and prescription

The Chinese medicine composition that the present invention relates to animal, vegetable material and prescription thereof is a raw material, extracts in the Chinese crude drug and the method for effective ingredient in the compound composition.

It is with a long history that the Chinese herbal medicine of China is used, and has been applied to clinical thousands of years, with clinical extensive use, accumulated abundant clinical experience through the successive dynasties medical expert, also abundant in development so far, becomes the rarity of the Chinese nation.

Traditional Chinese patent medicine ball, loose, cream, pellet, but take with the form of decoction more effective, with strong points, instant effect.But, because the person's of boiling medicine proficiency level's difference, be easy to cause the uncertainty of loss of active ingredients and effective dose in the Chinese medicine, bring to subtract effect, even invalid drawback, also be not easy to journey and take.And decoction mostly is two and fries in shallow oil, and divides secondary to take, and causes to take the saying of decoction the hot summer days, influences treatment of diseases.

Traditional Chinese patent medicine ball, pellet are that raw materials of traditional Chinese medicinal materials is ground into fine powder, add adjuvant and form Chinese patent medicines such as ball, pellet.Be unfavorable for the absorption of the intestines and stomach to the effective ingredient in them after taking, many effective ingredient arranged not by stomach, intestinal absorption, Effective Components of Chinese Herb just is excreted with Excreta.

Worked out the form of Chinese drug of oral granule electuary in the last few years, but adjuvant is too much in the oral granule, and adjuvant mostly is saccharides such as sucrose, lactose, the consequence that causes diabetics to take.

Chinese patent literature application number 00107662.0, the applying date is on May 25th, 2000, has reported and has exempted to fry in shallow oil preparation method of Chinese medicine.This method is to be raw material with the Chinese crude drug, adds entry in normal pressure mixture effective ingredient in the heating extraction Chinese crude drug under 60～100 ℃ temperature, win time extracting solution and medicinal residues for the first time; Add entry to the first time in the medicinal residues, carrying out the second time extracts, get extracting solution and medicinal residues for the second time for the second time, merge secondary raffinate in pressure 0.02～0.09MPa, carry out concentrating under reduced pressure under 30～90 ℃ the temperature, be condensed into the fluid extract of proportion 1.20～1.35, after the medicinal residues drying, be ground into the medicinal residues fine powder for the second time; The fluid extract of medicinal residues fine powder and proportion 1.20～1.35 is mixed, form mixture.Mixture is carried out spray drying generate the medicated powder granule.The decoct type of producing in this way of exempting from, having decoction is easy to be absorbed, produce effects is advantage rapidly, water one dashes the formation suspension and can take, be convenient to take during the journey, be easy to again preserve,, take the health that the medicine that contains a large amount of Plant fiber is of value to human body owing to increased the Plant fiber in the medicine.But also there is weak point in this method, and its weak point is exactly still to have effective ingredient through in the medicinal residues of second extraction, do not extract, medicinal residues can not be digested and assimilated out in the intestines and stomach of human body, and excrete, and do not have absorbed effective ingredient not obtain utilizing.

How extract the effective ingredient in the Chinese herbal medicine is as much as possible, preferably 100% extracts active ingredients in the Chinese herbal medicine come out, this technical task pendulum Study of Medicinal Herbs person in face of.In prior art, in Chinese herbal medicine, add the water of Sq, second extraction is carried out in heating, even extracts for the third time, can not the effective ingredient in the Chinese herbal medicine be extracted more.This is that when adding the water heating extraction, its effective ingredient diffuses out by cell wall gradually because the effective ingredient in the Chinese herbal medicine is present in the cell of animal and plant.And in existing Chinese herbal medicine extracting process, only be the extracting solution medicinal residues to be separated by filtering, and the extracting solution that is present in the medicinal residues also contains the medium-height grass the effective elements of the medicine, and the effective ingredient that is present in like this in the medicinal residues is lost in vain, and the effective ingredient in the Chinese herbal medicine is incurred loss again.The present inventor has worked out a kind of method that effective ingredient in the Chinese herbal medicine is extracted more through years of researches.

Purpose of the present invention just is to work out a kind of simple, effective, the method that the mixing effective ingredient in the Chinese herbal medicine is extracted more.

The method that effective ingredient in the Chinese herbal medicine is extracted more of the present invention is based on has taked a kind of breaking cellular wall extractive technique.Said wall breaking technology is exactly that the medicinal residues of Chinese herbal medicine after adding the water heating extraction are handled through squeezing.In expressing process, the extracting solution that will be present in the medicinal residues is extruded out, and the more important thing is medicinal residues by expressing process in, make the cell wall rupture in the animal and plant, make in the Chinese herbal medicine effective ingredient more, even be extracted out fully.

The breaking cellular wall extracting method of a kind of Chinese crude drug of the present invention and prescription, root, stem, skin, leaf, flower, fruit, seed with natural medicinal plant, wherein a kind of of the medicinal part of natural medicinal animal, and press the required Chinese crude drug compositions of pharmaceutical formulation after pretreatment as raw material; Add entry in raw material, the mixing effective ingredient is extracted in heating under normal pressure, obtains extracting solution and medicinal residues for the first time for the first time; To the first time medicinal residues under the pressure of 1.0～5.0 kg/cm, carry out the breaking cellular wall squeezing first time, make the cell wall rupture in the raw material, and make the extracting solution in the medicinal residues be extruded out, time press liquor and of winning for the first time through the medicinal residues of squeezing; Make it loose in water to adding entry for the first time in the medicinal residues of squeezing, stirring, the extraction second time is carried out in heating under normal pressure, obtains extracting solution and medicinal residues for the second time for the second time; To the second time medicinal residues under the pressure of 1.0～5.0 kg/cm, carry out the breaking cellular wall squeezing second time, press liquor and for the second time through the medicinal residues of squeezing for the second time; To in the medicinal residues of squeezing, adding entry for the second time, stir and make it loose in water, under normal pressure, heat and extract for the third time, get extracting solution and medicinal residues for the third time for the third time, medicinal residues for the third time under the pressure of 1.0～5.0 kg/cm, are carried out breaking cellular wall squeezing for the third time, juicing and through the medicinal residues of squeezing for the third time for the third time, extracting solution and press liquor are carried out concentrating under reduced pressure, make it be condensed into the fluid extract of proportion 1.10～1.35.

Said pretreatment to Chinese crude drug is exactly to select up-to-standard Chinese crude drug, and the assay method with country's mark product analyzes as content of effective in the Chinese crude drug of raw material, sees whether it meets desired standard.Water flushing medical material, limpid until the color of water, remove impurity, again medical material is dried or drenches and do.In order to improve to mixing extraction ratio of effective constituents in the medical material, can be cut into sheet, bulk or be ground into graininess, for example be ground into the 40-80 order, this is that those skilled in the art all know.Certainly the Chinese crude drug that yet has can not cut into slices yet, piece or be ground into granule.The medical material that has also needs to soak before heating extraction, soak suitable time, so that when heating extraction, help mixing the leaching of effective ingredient, the length of soak time is decided on the character of medical material, what have will soak 10-60 minute, that have even soaked 12-24 hour, what have makes the part of amount of water for the first time with soaking water, and this also will decide on medical material character.Used water is tap water, distilled water, deionized water a kind of water wherein.

In raw material, add entry, heating is extracted when mixing effective ingredient, the water yield that is added is 4～10 times of raw material weight, under normal pressure under 30～100 ℃ temperature heating extraction 2-8 hour, again with heating extraction 4-8 under 30～95 ℃ temperature hour for well, obtain extracting solution and medicinal residues for the first time for the first time.To the first time medicinal residues under the pressure of 1.0～5.0 kg/cm, squeeze, make the cell wall rupture in the raw material, make the extracting solution in the medicinal residues be extruded out again, time press liquor and of winning for the first time through the medicinal residues of squeezing.To in the medicinal residues of squeezing, adding entry for the first time, the water yield that is added is 2-8 a times of raw material weight, stir, the speed that stirs does not have any influence to product quality, the effect of its stirring make through the medicinal residues of squeezing for the first time loose in water after, under normal pressure under 30～100 ℃ temperature, heating extraction 2-6 hour.Be advisable with heating extraction 2-5 under 30～95 ℃ the temperature hour again, get extracting solution and medicinal residues for the second time for the second time.To the second time medicinal residues under the pressure of 1.0～5.0 kg/cm, carry out the breaking cellular wall squeezing second time, press liquor and for the second time through the medicinal residues of squeezing for the second time.To in the medicinal residues of squeezing, adding entry for the second time, stir and make it loose in water, the water yield that is added is 2-6 a times of raw material weight, under normal pressure under 30～100 ℃ temperature heating extraction 2-4 hour, be good with heating extraction 2-4 under 30～95 ℃ the temperature hour again, get extracting solution and medicinal residues for the third time for the third time.Carry out breaking cellular wall squeezing for the third time under the pressure to dregs of a decoction 1.0～5.0 kg/cm for the third time, press liquor and medicinal residues for the third time for the third time through squeezing.Used equipment was sheet frame squeezer or screw hydraulic machine when medicinal residues were squeezed.

The extracting solution of three merging and the press liquor of three merging are filtered into the plate and frame filter respectively.Certainly the press liquor that also extracting solution and three times of three merging can be merged lumps together with the plate and frame filter and filters.Press liquor after extracting solution after the filtration and the filtration can carry out concentrating under reduced pressure respectively, carry out concentrating under reduced pressure after extracting solution after can also filtering and press liquor merge.Certainly unfiltered press liquor and extracting solution directly can also be carried out concentrating under reduced pressure.

To filtered or filter after extracting solution and do not have filtering or filter after press liquor respectively or merge and be placed in the concentrating under reduced pressure jar, at pressure 0.02～0.09MPa, carry out concentrating under reduced pressure under 30～90 ℃ the temperature, again with at pressure 0.02～0.09MPa, carry out concentrating under reduced pressure under 50～80 ℃ the temperature for well.Being condensed into the fluid extract of proportion 1.10～1.35, is good with the fluid extract that is condensed into proportion 1.10～1.20 again.

For the ease of storing, transporting and carry with water vapour gas, compressed air, nitrogen a kind of gas wherein is atomization gas, fluid extract is carried out spray drying, the pressure of atomization gas is 0.1～1.0MPa (about 1-10 kg/cm), and the pressure of atomization gas is good with 0.4～0.6MPa again.When spraying, fluid extract is sprayed in the hot-air by the shower nozzle of thermal foggers, carry out heat exchange.Temperature as the drying medium hot-air is 40～400 ℃, is advisable with 40～200 ℃ again.Fluid extract carries out the transient heat exchange in the hot-air of certain flow rate, make it rapid drying, forms the medicated powder granule, and the medicated powder average diameter of particles is 1000-2000 μ m.Water content 3-4% percetage by weight in the medicated powder granule.Used aerosol apparatus can be an air-flowing type, the mechanical type shower nozzle.

In order to increase the content of fiber in the medicine, will under 55-115 ℃ temperature, carry out drying through the medicinal residues that squeeze for the third time, exsiccant medicinal residues are ground into the medicinal residues fine powder, make the granularity of medicinal residues fine powder cross 40 orders-180 order.The medicinal residues fine powder is thin more good more.Again medicinal residues fine powder and fluid extract are mixed the formation mixture.In order to reduce the dosage of taking makes again increases fiber in the medicine content, mix to good with medicinal residues fine powder and fluid extract again, more mix to better with medicinal residues fine powder and fluid extract with the 15-25% of medicinal residues gross weight with the 10-40% of medicinal residues gross weight.When medicinal residues fine powder and fluid extract mixed, its mixing speed did not have any influence to the quality of product, as long as medicinal residues fine powder and fluid extract are mixed.After medicinal residues fine powder and fluid extract mixed, water steam gas, compressed air, nitrogen a kind of gas wherein was atomization gas, carries out spray drying.The pressure of spray gas is 0.1～1.0MPa during spray drying, and the pressure of spray gas is good with 0.4～0.6MPa again.Fluid extract and the medicinal residues fine powder mixture shower nozzle by aerosol apparatus is sprayed in the hot-air, carry out heat exchange.Temperature as the hot-air of drying medium is 40～400 ℃, is good with 40～200 ℃ again.After the fluid extract that contains the medicinal residues fine powder sprays in the hot-air, carry out the transient heat exchange in the hot-air of certain flow rate, make it rapid drying, form the medicated powder granule, the medicated powder average diameter of particles is 1000-2000 μ m.Water content 3-4% percetage by weight in the medicated powder granule.Because be instantaneous drying, be applicable to heat-sensitive materials, make it the effective ingredient that keeps original, and epigranular, the color and luster unanimity, granule is bonded crisp, is easy to moisture and soaks into disintegrate, enters to be beneficial to human body in the human body and to absorb rapidly, heightens the effect of a treatment.

Breaking cellular wall extracting method of the present invention is a raw material applicable to root, stem, skin, leaf, flower, fruit, the seed of natural medicinal plant, and the raw material of its medical material is:

A Lebo, ferulic, Blumea, leaves, benzoin, eucalyptus oil, Um Mollet, alangium, eight Angle gold plate, eggplant fragrant anise, hydrangea, August Sapporo, Croton, Morinda, sarsaparilla, white beans, white Chang, white cardamom, rice tree, white tuber, ginkgo, white wormwood, nosed pit viper grass, white, and, white spines, white Mustard, white lettuce, white Euphorbia, Ampelopsis, Solanum complex hay, cogongrass rhizome, white front, celandine, TGP Atractylodes, bulbul, fresh white skin, Baiyao son, one hundred, lily, one hundred feet, one hundred edge Teng, Lotus root, Boye, Bozi, Patrinia, Radix, lobelia, Fritillaria, Bi Cheng Ke, Piper longum, castor seed, fresh, Castor, the provision of snake Lei, flat storage, lentils, yellow everywhere, betel nuts, Persian grass, Bo Wood, psoralen, cloth Slag leaves, silkworms network grass, fruit, herb, grass Fritillaria, beans, grass, grass and fruit, grass Ho, Oriental Arborvitae, Ear, side-son, hairpin sub stocks, Bupleurum, periwinkle, ivy, Changshan, overturned cans, Plantago, Aloes, Chen Lin rice, orange peel, tamarisk, red car messenger, red terrain, red willow, red bean, Chong Wei, Sabina, smelly Indus, Chu real son, Fritillaria, Sichuan off, Sichuan pepper, Toosendan, Chuanmutong, Chuan Zhu knee, Chuan birds, Chuanxiong, Andrographis, bottom moss, sarmentosum, hammer HU root Chunsharen, Tsubaki skin, Tribulus terrestris, Thorn old bud, Acanthopanax, light blue, yellow soybean volumes, soybean tiller scattered Hydnocarpus Arecae, rhubarb, Euphorbia, Daji, cannabis, barley, Daqing, Folium, garlic, big leaf snake Explorer, jujube, Tortoiseshell, Salvia, SSP, light aconite, light ginger, fresh bamboo leaves, parsley, beans, rushes, Stephania, the small grass, Kochia, Kochia scoparia, to yellow, Verbena grass, gall, to centipede grass, Elm, basil oil, Dongfeng dishes, Chinese caterpillar fungus, melon skin, Dong Kuizi, rubescens, holly leaves, Holly son, all as grass, are salty son, alone with the generals, Du Heng, Eucommia, broken blood of knots, Curcuma Surgery, geese hold, centipeda, France Pinellia, saffron, strychnine, senna, Tetragonia, PDB, Fan, chickweed, wind, anti Kwai, anti has, Polygonatum fat, fat acacia, Torreya real, Fern, impatiens, Impatiens Speranskia, Sedum, bergamot, volt chicken roots, mallard sunflower, hibiscus, Poria, duckweed, floating small Wheat, rot servant, aconite, ascites grass, raspberry, covered Potamogeton, ginger, dry paint, licorice, sweet banana Gan Pine, euphorbia, sweet cane, sugar cane, Gang Mei, Gang Song, Polygonum perfoliatum, galangal, Wara wood, Ge Hua, power Lo wood, Uncaria, Gelsemium, Woodwardia, holly, holly leaves, Juju, wolfberry, mushroom, wild rice, the ancient coffin Board, Eriocaulon, Guya, Drynaria, Trichosanthes, melon reed, manshuriensis, Guanzhong, patchouli, Guangxi Curcuma, Bidens, Gui, Ranae, the sea breeze rattan, pine son, Pittosporum skin, calla lilies, algae, Aqueous rattan, welding vegetables, myrobalan, Albizia, nuts, leaves, grass shoots crane, crane lice, black sesame, black Son grass, red grass, red clover, sage, safflower, safflower ivy, red and blue flowers, red Euphorbia, Red Lady, SFAS, Hericium, HU onions, picrorhizae, pepper, fenugreek, coriander, walnut meat, Walnut branches, poon tears, gummies, gourd, gourd, gourd, solid oak, saxifrage, tiger palm grass, tiger Sticks, pepper, ginseng, ginseng Huashan, Huai wood, Trametes, SJ, Huaijiao, yellow bulbil alone, yellow Ring, Huang Jing, berberine, sumac, Rattus ear grass, Huangshan red, bulbifera, yellow steamed, Wong, hemp Jen, Polygonum, rugosa, Intestinal grass, cockscomb, droppings vine, chicken Soviet Union, heart-shaped white with, Millettla, Impatient, grass, turmeric, cowpea, dalbergia, sauce, pepper head, Incarvillea, Gynostemma, Symphytum, Elderberry, detoxification son, mustard, mustard, gold insect rabbit ears, gold boiling grass Jingangteng, golden fruit sheets, gold scissors Sword grass, loosestrife, golden buckwheat, golden berberine, Hypericum, gold wire hanging hibiscus, Venus grass, gold and silver Flower, Rosa laevigata, marigold, Kam to Romania, loyal grass, Nepeta, Sedum, Sedum Panax, glossy grass, Nine wind, Guri light, nine cattle grass, nine fairy, moxibustion Hedysari, chive seed, leek son, will be saved, orange Terrier, chicory, orange peel, Dianthus, Selaginella, cassia, acanthus, bitter herbs, Sophora, bitter Fu, Kugan Grass, bitter Kwai Scorzonera, neem bark, bitter eggplant, bitter almond, bitter leaves, wide bars Teng, Coltsfoot, puppet corner, Kelp, Trichosanthes jacket, spicy rice dishes, vegetable turnip son, Blue Lake, Bidens, Geranium, tiger thorn from Ge grass, Lai fact, litchi, forsythia, lotus, lotus, lotus grass, two sharp, bright bacteria, Liaoning leaves, smartweed, Polygonum Folium, Ganoderma lucidum, Campsis, guaiac, Siphonostegia, Liu plastic, hexagonal vine, often grass dragon, the dragon Flabellata, Solanum nigrum grass, Long Lee leaves, dragon tongue grass, asparagus, cocklebur, longan meat, drain basket, Loulu, Honeycomb, reed, reed rhizome, aloe vera, Lu Ying, wintergreen, Passepartout, Lv beans, clothing, legal grass, green beans, Lve plum, Luan Jing, Apocynum leaves, Mangosteen, Lo Kwai, Luoqun belt, Rauwolfia, Luomo, contact stone, Contact Ishido, ephedra, ephedra root, Quercus parasitism, verbena, puffballs, purslane, Aristolochia, MA Lin son, Ma Qi, nux vomica, horsetail connected Pedicularis, Radix, wheat basket, malt, selling sub-wood, Mountain incense, pepper vine, Vitex, Mangcao, Mao Bo, Mao melon, goldenseal, hair myrobalan, wool smartweed, bamboo shoots, Mao raspberry roots, roses, raspberry leaf tea, Potentilla, Maytenus, monkeys pear root, millet Wu, rice husks, rice koji, Buddleia, castor seed cotton, smyrnioides, Eclipta, moutan, Artemisia, wood Dan, fungus, Hibiscus leaves, Papaya, wood butterfly, hibiscus, hibiscus bark, wood hellebore, magnolia, wooden bread, kapok, veneer, Wood Granville, Equisetum, wood Chicago, alfalfa, pumpkin seeds, South Lappula, South rattan, Nandina son, South candle, Molle flowers, tillers m, Caragana, burdock, cattle flat, ui rhubarb, horn melon, Achyranthes, agricultural auspicious, Slaves Zhe, YWCA, female Ivana, female wilt, Ligustrum lucidum, glutinous rice root, glutinous rice roots, Oujie, climbing down steamer, Panda Hai, Perrin, phaeocaulis, leaves, hops, brandy bottle, Borneo too, Portuguese volts Jin, Pu The British public, Puhuang, Palmetto, Hayata, polyphylla, chestnut, daughter dishes, daughter grass, Stephania, Leptochloa, Senecio, Trinidad and Millennium Ai, the Millennium rat feces, the Millennium built Pharbitidis, Peucedanum, Gorgon, madder, Qin pepper, Qin skin, Artemisia annua, green wood, peel, seeds, leaf gall, Abutilon Music festival grass, flesh and to the Son, Wikstroemia, honeysuckle, Cistanche, nutmeg, milk thistle son, into the earth Taurus, Rui grass, Rui flowers, bamboo, three Pennisetum, trigeminal pain leaves, Cephalotaxus, three-pin, triangular, Panax, Thirty-six swing, Morus alba, mulberry flowers, mistletoe, mulberry, mulberry leaf, mulberry, Radix, complanatus, Yarn wood surface, Amomum, sedges, Arrowhead Mountain, Mountain onions, tonkinensis, mountain conch, lotus mountain, mountain leek, Kaempferol, mountain peach, yam, mountain oil orange skin, hawthorn, mountain sesame, pokeweed, shochu, Cnidium, Snake with, Duchesnea, snakes grape root, Shegan, The Divine Comedy, kidney tea, black cohosh, up medicine, ginger, Calamus, Mahonia, Shichangpu, stone penetrated, stone melon, Dendrobium, stone see through, abalone, peel, Shilong Chu, Long Rui, skinks, heather, Selaginella, Lycopodium, Lycoris, Shi Wei, carnation roots, Food cornel, dill, so that a gentleman, Shi Di, gecko, millet, rhamnose, Gnaphalium, sage, hollyhock, Shu Yang Quan, tree flowers, water, licorice, Polygonum orientale, water rats, water smartweed, Shui-ping, water bayberry, gourd Network, holly leaf, four leaf, pine section, rosin, woad leaves, Deutzia, Su Fang wood, Styrax, Sue Wood, Suzi, Physalis, Physalis Velvet, sorrel, Aesculi, Suocao, Cynomorium, heterophylla, Tan Huan, Sandalwood, Tang Di, peach, special Jing Ye, Fujiko, aspartame, TCS, Tianma, day names fine, day eggplant Son, the day Zhuhuang, Tenjikukatsura, Hypericum, Tinglizi, through the grass, scattered light through, pass off the wood with tarragon, Bolbostemma, Rumex, earth Fu Qin, earth astragalus, soil wattle bark, soil horsehair, Achyranthes, dodder seed, Corrugated son, Vaccaria, Wang melon, Wang melon roots, princes, occidentalis, Clematis, Wei title, tail banana Leaves, reed roots, acaulis, Wei Mao, horsetail, Japanese ground tea, lettuce, black bone vine, black grabbing poison, ebony, Ebony, aggregata, house tour, figs, Sapindus, seamless son, nameless essence, no food son, Evodia, Turnips, Wu weed, the Indus, gall, Wujiapi, Wulong root, Schisandra, spiced cuneata, Wu Xin | Western bean root, saffron, ginseng, Xi Xian, Asarum, Prunella, Agrimony, Curculigoside, fairy Human palm, amaranth real, incense, abrin, lemonade, sweet, fragrant fruit, Periplocae, Elsholtzia, sunflower, Little Bai Wei, a small one hundred, red ginseng, fennel, thistle, Xiaoqing, a small day garlic, evil tarragon, shallot, scallion White, magnolia, Xinhui skin, apricot ginseng, almonds, Xu Changqing, Dipsacus, capers, Yi roots, Scrophulariaceae, Rubus, Inula flower, lotus, snow artemisia, leukemia grass, blood over charcoal, look for bone wind, javanica, Commelina, Cliff Brown, Asia almost slaves, Daphne, bergenin, salt, bran, oats, okra, Yang Tao, Datura, Chrysanthemum, wild tomato roots, the bottom of beads, Phyllanthus, a yellow, caramel, motherwort, Puzzle, Shade Jue, burmannii skin, capillaris, skimmianine, silver purple HU, poppy, opium poppy son, camp reality, By the Postscript, Caryopteris, emblica, Houttuynia, elm mushroom, elm kernel sauce, Yu white with, Limonitum, Yuzhou Loulu, Corn, corn, Polygonatum, taro, Yuli, predict child, per inch, wall clothes, Polygala, month Season flowers, Yue Yu shoots, Caesalpinia, Coriolus versicolor, chisel food, bad, stove subsoil, soap thorn, Zaofan, acacia, Zeeland, Euphorbia, Alisma, Zhan Xiang sugar, accounting for rice, accounting for Sri Lanka, Tsugeki, gradually Fritillaria, loosestrife, Anemarrhena, Citrus aurantium, made grass birds, nature Khan, Zhi PCT, heavy floor, heavy pots grass, Castanopsis son, Panax japonicus, Zhu Li, Zhuru, Bamboo, ramie, ramie roots, Azusa, purple Poisson, purple white teeth, purple back gold plate grass, comfrey, purple ivy, Viola, Aster, Bignoniaceae, Bignoniaceae flowers, brown boards, palm, palm charcoal, buddleia, yesterday Ye Ho Grass, grass to get to sit. ...

Breaking cellular wall extracting method of the present invention is applicable to that also the medicinal part of natural medicinal animal is a raw material, and the raw material of its medical material is:

Colla Corii Asini; Carapax Trionycis; Squama Manis; DILAOSHU; the roach horsefly; Gecko; yellow moccasin flower; Oviductus Ranae; Testis et Pentis Canis; Omphalia; Borneolum Syntheticum; Tabanus; thousand-legger; Bombyx Batryticatus; Cutis Bufonis; Corium Erinacei Seu Hemiechianus; Pheretima; Mel; Carapax et Plastrum Testudinis; Rhizoma Dysosmae Versipellis; shell is breathed out in the sea; Endothelium Corneum Gigeriae Galli; Cornu Saigae Tataricae; Borneolum Syntheticum; Concha Ostreae; Scorpio; Mylabris; Venenum Bufonis; Eupolyphaga Seu Steleophaga; Herba Cardui Crispi; Agkistrodon halys; the ghost tooth; the ghost head; Os Tigris; Aspongopus; Os Draconis; Cornu Cervi Pantotrichum; Calculus Bovis; Ootheca Mantidis; Moschus; Cornu rhinocerotis; Radix Rumicis Japonici; Radix Curcumae; Margarita; Concha Margaritifera; Folium Callicarpae Formosanae; Scolopendra; Fel Ursi; rhododendron molle (bl.) g.don; Camphora; Blatta seu periplaneta; leaf fat juice; Rhizoma Ardisiae Gigantifoliae; Oletum Trogopterori; Lac caprae seu ovis; Air Bladder pseudosciaenae seu Acipenser; Margarita; Placenta Hominis; Hirudo; Herba Kyllingae; Os Sepiae.

Breaking cellular wall extracting method of the present invention is applicable to that also the Chinese crude drug compositions of Chinese patent medicine dosage form prescription is a raw material, and its prescription is:

Protect Ji side, reinforcing spleen and benefiting intestine side, tonifying kidneys and nourishing brain side, ginseng spirit side, ginseng stilbene side, the ginseng and pilose antler side of preventing miscarriage, the ginseng Soviet side, Chuan Xiong Tea side, big active side, rheumatism panacea side, gynecological's prescriptions worth thousand gold, coronary heart disease side, coronary disease Su Quan side, the Huatuo side of reproducing, heart side lives, add the carefree side of flavor, blood sugar lowering side, pieces of Jin ' gui shenqi side, anti-bone regeneration side, the lingbao huxin folk prescription, six drugs containing rehmanniae side, the Radix Aucklandiae divides gas side, the pleasant side of the Radix Aucklandiae, NAODESHENG side, suppressing the hyperactive liver is dredged network side, seven all gas sides that distinguish the flavor of, Lycium-rehmannia side, prostatitis Shu Fang, Fructus Canarii side, the Radix Ginseng side of reproducing, crataegus pin natifida var. Majorization stagnates square, supernatant side, dendrobium noctilucent side, four pros, Rhizoma Gastrodiae side, Tongxuanlifei side, gastrointestinal peace side, Calculus Bovis from Northwest of China side, cyperus-amomum stomach side, fragrant sand trifoliate orange art side, the side of quenching one's thirst, wart side disappears, children's relieving dyspepsia side, heart treasured side, Radix Panacis Quinquefolii is protected lung side, YISHEN JUANBI side, Yinqiao detoxification side, Yuquan side, beautiful leaf detoxifcation side, body resistance-strengthening Zhenqi side, positive old name for the Arabian countries in the Middle East, ZHIBAIDIHUANG side, relieving cough and resolving phlegm side, China traumatic injury side, Parking side, bone strengthening joint side, bone and kidney health side, chase after the wind bone penetration formulation.

Breaking cellular wall extracting method of the present invention is applicable to that also the Chinese crude drug compositions of the prescription of famous-brand and high-quality soup side is a raw material, for example:

AnWeiTang, eight are soup, white split soup, white Poria soup, white soup, Atractylodes soup, Lily Tang, Bozi soup, Megalosaurus soup, half sulfur soup, Banxiabaizhutianma soup, Banxiahoupu soup, castor seed moss points broth, Bu Xin Tang, Buzhongyiqitang, not for gold righteousness soup SHENLINGBAISHU soup, fruit soup, Cai Ping Tang, intestinal Adhesions ease soup, red bean soup Angelica, Dasheng soup, soup up, big Radix soup, soup qi, Dabuyin soup, nourishing Yuan Tang, Dachaihu soup, Dachengqitang, the wind calmed down bead soup, rhubarb worm soup, Yellow aconite soup, rhubarb licorice soup, rhubarb berberine Xie Xin Tang, rhubarb soup peony, rhubarb soup, has cold Soup, Daikenchutou large orange peel soup, soup Daqin macrophylla, junior fifty-seven soup, Xianxiong soup, Salvia soup, Biliary row of stone soup, Dangguibuxuetang, Angelica back against Tang, Angelica six yellow soup, ground yellow soup, ground Mao Yin Zi, Tiaowei decoction, tune in Shun Qi Tang, cloves Jiaoai soup, cloves Shi Di Tang, Dingchuantang, Sadashi soup, Two winter soup, two yellow soup, two subtraction righteousness soup, dimethyl fumai soup, two wonderful soup, two female Ning rinse soup, two God of soup, two raw soup, Immortals soup, two to soups, Fang Feng Tong Sheng Tang, fat children soup, sealing marrow soup, aconite Terrier Rice, aconite Xie Xin Tang, ginger soup aconite, licorice ephedra soup, sweet bean soup, mannose disinfection soup, sweet Then pass knot soup, Gehua wake soup, dressing soup, solid fine soup, solid in soup, melon wilt scallion white soup, spleen soup, Guizhifuling soup, Guizhi soup, seaweed soup okho, Terminalia soup, soup warm in Magnolia, flowers Herd soup, chemical Spot soup, soup of the liver, blood soup, berberine gelatin soup, HJD, Huanglong soup, Astragalus fangchi soup, Huangqi Guizhi Wu Tang, skullcap soup, loess soup, active effect Ling Tang, has pepper Lihuang soup, Jisheng ebony Tang, Jian Ling Tang, spleen soup, ginger decoction, Whey soup, Jiaoai soup, Jin Ling Zi soup, golden solid impregnable, Nine yellow soup, nine turn Huang Jing Tang, bellflower soup, orange peel Zhuru soup, bacteria Chen Hao Tang, open silent soup to re-soup, Lian Li Tang, even Pak soup, good with soup, Kuni given in the soup, Liujunzi, Liu Wei Di Huang Tang, reed rhizome soup, Ma Gan Mixture soup, Ophiopogon soup, moutan soup, papaya soup, woody nut soup, woody notes decoction, Drinking water woody, woody Shun Qi Tang, within the thinning berberine soup, soup bezoar, bezoar overflow impregnable, Pinggan Gloomy Bleeding soup, soup coming Ama America, Shippo soup, soup Qili 2,730 Dan Tang, Qi Fu Tang, daughter of reed stems soup, Notopterygium punch and soup, skullcap Gui Zhu Gan Tang, bowel soup, soup breeze, Qing Tang, throat clearing soup, clear the soup, Empty soup, Qingluo drink, drink clear spleen, clear detoxifying soup, Qu Shu Tang, Renshenbaihu soup, ginseng sepsis Soup, ginseng soup cardamom, ginseng Gecko soup, ginseng soup Qingzhen, ebony ginseng soup, ginseng yangying, Life plaster soup, intestines soup, three bend soup, three Bi Tang, sealed with God marrow soup, three of soup, three wonderful soup, Thirty-seven coronary tablets, San Ren Tang, three things emergency preparedness soup, three things Elsholtzia soup, three sons to support pro-soup, Sang Ju Tang, Sang Xing Tang, peony and licorice soup, peony soup, kidney with soup, Pueraria cohosh, black cohosh disinfection soup, l trap Tang, Sun Yiwei Tang, biochemical soup, laughing soup, Shiquan Yu Zhen Tang, Jian Zhong Tang fourth flavor, Shiwei reed Su Tang, Shiwei Xiong Su Tang, stone lotus seeds soup, Shi Wei Tang, Shou spleen fried, surgery with soup, double up soup, double flowers Soup, soup dual solution, four worm soup, four yellow soup, four Ling Tang, Simotang, forty-seven soup, four raw soup, four beasts Soup, four Wei Xiang Ru Tang, Si Wu Xiao Feng Tang, four system Cyperus soup, Suzi lower gas soup, tai chi soup, Tarzan Rock soup, Tianmagouteng soup, soup clearance, Tongqiaohuoxue soup, soup and pain Tory, Tory Qingdu soup, Complete with soup, look plum soup, soup reed stems, Wenpitang, very yam soup, five Bi Tang, tigers soup, Wulin Soup, Wuling soup, five skin soup, five benevolence intestines soup flavors xiaoduyin, five juice drink Sonangol, Yanzong Soup, wash the liver soup, fragrant soup, Xiangsha Liujunzi, incense Evodia soup, Diabetes soup, Xiao Jian Zhong Tang, Xiaoqinglongtang small temperature in the soup, small black Shen Tang, Xiaoxianxiong soup, diarrhea yellow soup, Xie Xin Tang, Xiong Shu Tang, Hydrangea Wind soup, soup Scrophulariaceae cohosh, Xuan Fu Dai Zhe Tang, Yang and Tang, Yangyinqingfei soup, always soup, a Subtraction righteousness soup, a bead soup, a twist impregnable, a bead soup, an overcast soup, soup Yi Yuan, Yin Qiao Tang, Yupingfeng soup, soup Yuzhen, Yuet Wah Tang, Tang Yue Ju, reconstituted soup, live survive soup, Zhenganxifeng soup, Zheng Yang Li Lao Tang, provision for sausage soup, Cough soup, citrus aurantium Daozhi soup, Zhishixiaopi soup, soup governance, Governance cloud consolidate soup, licorice soup, the soup out of elimination, Xianzhuli up phlegm soup, bamboo Liu burdock soup, soup in King, AIDS dry yangying, Zuogui soup, left impregnable, Ann Mitac Yu Tang, Ann kidney soup, Sonangol soup, Bawei buck Soup, stew Lily Wu Lai Tung, one hundred Almeida gods drink, Bao Yuan Salvia drink, work stasis stasis soup, lungs Dingchuan side, Yin Huang Tang, fill in Xiaopi soup, ginseng clams Maxing cream, grass Ho Tang, Bupleurum turtle soup, Bupleurum Decoction Bupleurum Decoction three stone, Bupleurum Zao Ren Tang, Chaishao and stomach soup, expectorant Ann Mei Tang, Hoe cloud cough soup, Daimai Yangfeihuoxue cough soup, tune network drink Tiaopi pass knot soup, winter cough cream, two ground Hypoglycemic drink, dimethyl tiaogan soup mixture pneumonia, pneumonia soup, rousing soup, Fugan grass square, Fugan Fang, rehabilitation consolidate soup, sweet wheat Gentian Decoction, Ganrun Qing lung soup, cirrhosis basic side, GE hongtangsi, Gu Shen Fang, melon wilt Xie Xin Tang, Kwan diabetes special party, Kwan headache prescription, consistently mulberry drink, go Gung Participation Qi wheat flavor soups, Gui HJD, and liver soup, and the soup in the nerves, and the Xiaopi soup, soup of liver detoxification, Huayu soft liver soup, Huang Jing four grass soup, beans Puxia Ling Chai Chendan grass rhubarb soup, subtraction Poria side, add Less helioscopia soup, subtraction Cough square, flavored BanxiaxiexinTang, flavored Chai Hu Tang, Jiawei Huang Jing soup, add Berberine Wendantang taste, flavored wheat flavor yellow soup, flavored water guide god Gung soup, flavored Simiao given soup, add Taste clearance parties, plus Wei Xiang Su drink, flavored Yiguanjian, flavored Yi Gong Party, flavored YinQiao side, less taste three Stone Soup, spleen Ditan soup, spleen solid intestine soup, liver and spleen party Jianpiyishenfang, fitness solid form soup, Jian Wan Mai Guya soup, lotus dependent intestinal ginger soup, hypoglycemic side, hypoglycemic Recipe, Jiangzhitongmai drink, Jiechuantang soup, Cough square cut, cut whooping soup, relieving phlegm and asthma soup, Goldwater Jiaotai soup Kanenobu Cyperus soup off the next Jiuxie Soup, Juanxiao soup, Cassia Uncaria soup, open lung Tongrun guided soup, anti-change nephrotic square, wide Zhongda Yu Tang, Yan Xin Lan er drink, elderly constipation side, away from the Ming Shen Qi Tang, cooling Liver soup, sixty-five Huang Tang, aloe Laxative gum side, Luks hepatitis B side, hemp almond soup capillaris forsythia, Maxing Ophiopogon soup, shot gall Maxing Tang, Ning Fang chronic hepatitis, chronic kidney soup, Ning Xin cough drink, Ning Yuan Fang, Ning Yuan Tang, spleen function square, migraine I, II, Fang, asthma fixed gas side, asthma wheeze given party Pinggan clearing the lungs soup, dogwood Qi Zhong Bo Tang, Qian Yang God rather drink, Notopterygium Taohongsiwutang, Qiangshen Xiezhuo fried, Bik side, clearing the lungs transfer of blood soup, clearing the lungs cough fixed Soup, soup buck Liver, Liver migraine side, Liver soup, Thanh Hoa Sini side, Thanh Hoa yishentang, clear Li intestine soup, heat Sanjie soup, moist soup, Qingshu Dingzhong soup, Qingxie Tonglin Tang, Qingxin ShengmaiYin, Clear in Xiaopi soup, slow renal Jane Jo's experience Wan, chills and antispasmodic soup, Rong liver soup, Rougan HJD, Liver and spleen contraction soft side, soft liver soup, triple soup, scattered Wei Qing Qi Tang, Radix stomach soup, sand semi-management in the soup, Decoction snake dragon, fairy clothing bait parties cohosh licorice soup, thirst soup, Amur laxative side, liver Decoction, liver soup of disease, liver detoxification soup, liver and open lung soup, liver and consumer product side, double Ji Fang, Double down soup, Courtyard soup, soup four sons asthma, diabetes side, effects colds Ning Decoction, jaundice three Grass soup, Spirit, fever, swollen back side, stomach slowly wilt recovery soup, warm liver soup, Warming management in the soup, yang fall Decoction, ebony Patrinia party, Wu Fang subtraction Cough, streaky Shao grass soup, fairy orange soup, Xiangsha warm in the soup, Xiangsha Yiwei Tang, diabetes side, consumption of water Dan, asthma Xia Zhi Fang, Xie Shu Tang, Xin Yun and Lung Tang, Xin Yun Xuanfei cough soup, qi and blood soup, Yang and asthma soup, nourishing the heart Sadashi soup, nourishing expelling wind, nourishing Fried intestines, raising Yin Jianzhong soup, pour soup of God, Qi Bao Yuan Tang, Yiqi Huayu Bushen decoction, Yiqihuoxue Fang, Qi Jian Zhong Tang, Qi detoxification drink, kidney detoxification soup, Yixin brain soup, beneficial blood soup cool, Liver Yin Yu Tang, Zhang Fang nephropathy, actinolite wilt Tang Zhen, the town of Anshen soup, cough Dingchuantang, Zhuru Qingwei drink, owned kidney Qi Tang, nourishing the liver and kidney side, Zi stomach drink, Yin pass down side, Yin yishentang, Zuogui Ophiopogon soup, MHT, Twig Pueraria, Pueraria, Gui ephedra half soup, Guizhi Two ephedra a soup, Guizhi two more handmaiden a soup, soup more servant, "daughter" the more handmaiden surgery plus soup, defense has been Astragalus Soup, soup Twig Astragalus, Astragalus peony Guizhi bitter soup, "daughter" ephedra wine soup, dragon Soup, clam soup, Magnolia seven Wu Tang, Chaihuguizhi soup, red bean soup ephedra even light carriage, Guizhi Ginseng, Aconitum Guizhi soup, plus Pueraria Decoction, Modified Guizhijiahoupoxingzi soup, Aconite Decoction ephedra, ephedra Asarum Aconite soup, Gui Gui to add Poria Atractylodes soup, go peony Tang Gui, Gui go peony plus aconite Soup, Twig aconite soup, bamboo soup, "Near effect side" technique with soup, Gui new add soup, Gualou Guizhi Soup, licorice gypsum hemp almond soup, Tinglizi Xiefei jujube soup, "daughter" reed stems soup, licorice ginger Soup, "daughter" Ginger licorice soup, Gan Ma Huang Tang, Magnolia ephedra soup, soup helioscopia, plus Xiaoqinglong Gypsum soup, add more servant Decoction, Guiling flavors of licorice soup flavors Ling Gan Jiang Xin Tang, Gui five sweet Grass to add ginger Asarum Decoction Gui, Ling Gan Jiang Xin flavors plus half Xia Xingren soup, "daughter" Guizhi go Peony plus acacia soup, Ling Gan Jiang Xin Banxing rhubarb flavors plus soup, Guizhi soup, Guizhi keel Oyster soup, oyster Shu Qi Gui go peony plus keel save inverse soup, SND, Sini plus Ginseng, White Pass soup, White Pass plus pig bile soup, Tongmai SND, tongmai Sini plus pig bile soup, Trichosanthes wilt Xiebai half Summer soup, Trichosanthes wilt Xiebai wine soup, Trichosanthes wilt Xiebai Guizhi Tang, Poria Decoction almond, orange orange ginger, Guizhi soup ginger citrus aurantium, Twig keel oyster soup, Ganmai Dazao, lily Anemarrhena soup, Baihe Yellow soup, chicken soup lily, talc Daizhe soup, lily Washing side, defense has to yellow soup, white tiger soup, bamboo Gypsum soup, soy soup gardenia gardenia licorice soup sauce, ginger soy soup gardenia, Gardenia Magnolia soup, citrus aurantium Gardenia Miso Soup son, Li Zhong Tang, Huangqijianzhong soup, rice stems aconite, nine hurt nine large Aconitum fried, big Breit Soup, "Taiwan" cursory soup, BanxiaxiexinTang, ginger Xie Xin Tang, licorice Xie Xin Tang, gardenia ginger Soup, Ginger Ginseng skullcap berberine, berberine soup, "Taiwan" HQT, Poria Atractylodes licorice Guizhi Soup, soup Alisma, Poria Alisma soup, "Taiwan" Poria drink, Xiaobanxia soup, less than half XIA Poria soup, Ginger Decoction, Gui go Ephedra Asarum peony tuber plus soup, ginger Pinellia Magnolia Licorice Ginseng, Zhizhu soup, anti has Poria soup, soup peony Twig, Twig rhubarb soup, Pulsatilla soup, bald Weng licorice gelatin soup, Inula soup, Dangguisini soup, raw ginger Dangguisini plus Evodia, when Normalized ginger mutton soup, Xuanfu Daizhe soup, Bentun soup, DXT, Suanzaorentang, Shaoyaogancaotang Fuzi Tang, wind lead soup, soup ephedra cohosh, Guizhi Fuling large KM, Fuzi Tang, Gan Jiang Ling surgery Soup, Twig Gui soup, Zhulingtang, pig skin soup, Poria Sini Tang, Xiao Chai Hu Tang, Bupleurum go Breit Trichosanthes root wilt plus soup, raw ginger plus Pinellia skullcap, Bupleurum plus Glauber soup, Chaihujialonggumuli soup, firewood HU Gui branches ginger, Dachengqitang small decoction, Magnolia three things soup, Magnolia rhubarb soup, fried honey guide Fang, Fang pig bile, fried pig fat cream, only when the soup, soup berberine Pueraria skullcap, purple Ginseng, halloysite Yu Surplus soup, euphorbia Decoction, THCQT, Poria quit salt soup, Xiayuxue soup, warm soup, red Blue Huajiu, "daughter" three things skullcap soup, rhubarb euphorbia soup, "daughter" outside Angelica Kin Tang, Loess soup, Boye soup, ginger gum, Cimicifuga turtle soup, "ancient recorded test" Xiaoxuming soup, "daughter" Three yellow soup, Guizhi Fuzi Tang, Atractylodes Fuzi Tang, licorice Fuzi Tang, ephedra surgery plus soup, Aconitum soup, Guizhishaoyaozhimu, White Tiger Guizhi soup, Coix Ma almond soup, oyster soup, ten KM, Cocculus have soup, Cocculus Glauber has gone gypsum Poria soup, licorice soup, bitter soup, licorice powder, honey soup, Sophora soup, smoked side realgar, Spike soup, hellebore licorice soup. ...

Breaking cellular wall extracting method of the present invention is applicable to that also the Chinese crude drug compositions of natural health food formula is a raw material, for example:

Fructus Psoraleae side, the ginseng red, the ginseng side of spending, ginseng and pilose antler side, Rhizoma Chuanxiong side, Radix Et Caulis Acanthopanacis Senticosi side, Radix Angelicae Sinensis side, Cortex Lycii side, Radix Rehmanniae side, old Radix Ginseng side, northeast, Cordyceps side, winter is returned Folium Mori side, Cortex Eucommiae side, Poria side, Radix Puerariae side, Rhizoma Cibotii side, Fructus Lycii side, return ginseng side, Radix Polygoni Multiflori side, Semen Sesami Nigrum side, pollen side, Rhizoma Polygonati ginseng stilbene side, the beautiful palpus side of Rhizoma Polygonati, Radix Astragali side, No. two, blood sugar lowering, No. one, blood sugar lowering, Ganoderma side, Aloe side, Radix Ophiopogonis slender acanthopanax side, Herba clerodendranthi spicati side, Fructus Cucurbitae moschatae side, Fructus Ligustri Lucidi side, Folium Eriobotryae side, Radix Ginseng side, Rhizoma Dioscoreae side, Fructus Crataegi side, Antilipemic haw side, crataegus pin natifida var. Major five tastes side, crataegus pin natifida var. Major silver chrysanthemum side, radix polygoni multiflori and radix salviae miltiorrhizae side, Radix Polygoni Multiflori side, Radix Polygoni Multiflori Radix Rehmanniae Preparata side, Radix Rehmanniae Preparata side, two Sang Fang, Herba Cynomorii side, Wu Huaifang, Wucan side, Fructus Schisandrae Chinensis side, Rhizoma Curculiginis slender acanthopanax side, Herba Epimedii side, Stigma Maydis side.

Breaking cellular wall extracting method of the present invention is applicable to that also the Chinese crude drug compositions in the medicated food formula is a raw material, as:

Flos Chrysanthemi minced meat medicated porridge, Gypsum Fibrosum Rhizoma Anemarrhenae medicated porridge, licorice ballonflower medicated porridge, Bulbus Fritillariae Thunbergii medicated porridge, Folium Bambusae medicated porridge, Gypsum Fibrosum reed Radix Astragali medicated porridge, Radix Ginseng Radix Astragali medicated porridge, Semen Coicis medicated porridge, Flos Lonicerae Semen Coicis medicated porridge, Fructus Momordicae medicated porridge, Semen Armeniacae Amarum Bulbus Fritillariae Uninbracteatae medicated porridge, Mel medicated porridge, Fructus Fici medicated porridge, three core medicated porridge, maize gruel, Radix Asparagi and Radix Ophiopogonis medicated porridge, lily gruel, Hylotelephium erythrostictum (Miq.) H.Ohba gruel, Lentinus Edodes medicated porridge, Gu golden medicated porridge, Rhizoma Dioscoreae Fructus Jujubae medicated porridge, very light blue medicated porridge, the Rhizoma Zingiberis Recens congee, point shellfish medicated porridge, Fructus Pruni shellfish medicated porridge, Carnis Serpentis medicated porridge, Bulbus Fritillariae Uninbracteatae Radix Raphani medicated porridge, Pheretima lobe of the lung medicated porridge, ground Rhizoma Nelumbinis medicated porridge, Bulbus Fritillariae Uninbracteatae lobe of the lung medicated porridge, eliminating the pathogens from the lung medicated porridge, Radix Aconiti Lateralis Preparata medicated porridge, Semen Persicae medicated porridge, Nodus Nelumbinis Rhizomatis medicated porridge, Fructus Pruni shellfish medicated porridge, lily apricot kernel medicated porridge, Semen Plantaginis medicated porridge, Fu Fructus Jujubae medicated porridge, Folium Nelumbinis medicated porridge, Gypsum Fibrosum Semen Coicis coriander medicated porridge, Herba Houttuyniae Fructus Crataegi medicated porridge, Semen Coicis Exocarpium Citrulli medicated porridge, Semen Abutili medicated porridge, Herba Portulacae lean meat soup, Umbillcaria esculenta Ovum Anas domestica soup, Rhizoma Zingiberis Recens Carnis Gallus domesticus soup, the thin soup of qibuliang, Thallus Porphyrae Radix Raphani soup, Caulis et Folium Ipomoeae aquaticae Corm Eleocharitis soup, Fructus Benincasae Channa argus soup, Semen Phaseoli gold carp soup, the Corii Sus domestica jujube decoction, Umbillcaria esculenta Ovum Anas domestica soup, Qi dish gold carp soup, the arhat Sliced pork soup, Bulbus Fritillariae Uninbracteatae meat unit soup, Lentinus Edodes blood fat reducing soup, band silk soup, turtle sore-throat relieving soup, the Trionyx sinensis Wiegmann yiwei decoction, the Radix Rehmanniae is made up lean meat soup, the Caulis et Folium Brassicae junceae beancurd soup, qibuliang lean meat soup, the red soup of pig, Semen Oroxyli is refuted egg drop soup, the Carnis Haliotidis chicken soup, hundred lotus lean meat soup, stew hundred bone soup in clear soup, purple Herba Amaranthi tricoloris medicated porridge, Herba Pogostemonis Folium Nelumbinis medicated porridge, Rana nigromaculata Folium Nelumbinis medicated porridge, Semen phaseoli radiati Herba Pogostemonis medicated porridge, Herba Portulacae medicated porridge, Exocarpium Citrulli medicated porridge, Gypsum Fibrosum Fructus Mume Folium Nelumbinis medicated porridge, Herba Kalimeridis medicated porridge, Folium Mori medicated porridge, Chinese cabbage Semen Phaseoli radiati Germinatus drink, prunus mume (sieb.) sieb.et zucc. prevents glycyrrhiza decoction, three juice drink, Herba Portulacae Radix Arnebiae (Radix Lithospermi) drink, Corm Eleocharitis Flos Lonicerae drink, Fructus Pruni fiber crops drink, five refreshing soup, Herba Alii fistulosi Jiang Dongpi drink, Folium Perillae Rhizoma Zingiberis Recens drink, Gypsum Fibrosum Fructus Mume Folium Nelumbinis drink, the three-coloured amaranth drink, Herba Pogostemonis Exocarpium Citrulli drink, the Herba Commelinae drink, Herba Apii graveolentis Fructus Jujubae drink, Semen phaseoli radiati Herba Menthae drink, the Herba Artemisiae Annuae drink, ash horse two Herba Amaranthi tricoloriss drink, Fructus Crataegi Flos Lonicerae drink, the Herba Plantaginis drink, Fructus Pruni Pi drink, the mixed nuts drink, the logical drink of temperature, lead the diffusing drink of Soviet Union, ginseng and pilose antler medicated porridge, the Flos Lonicerae Sliced pork soup, the Semen Ginkgo Meatballs soup, dragon boat soup, the Fructus Momordicae charantiae egg drop soup, the Chinese cabbage duck meat flat pieces of dough served with soup, the Ovum Columba livia Chinese cabbage soup, Chinese Cabbage and Tofu Soup, tonifying YANG Carnis Canitis soup, Saut soup, spinach soup, Flos Lonicerae Herba Menthae soup, Bellamya quadrata soup, Herba basellae rubrae soup, cold and dressed with sauce Herba Houttuyniae, fried season vegetable, the Fructus Cucurbitae moschatae Stewed beef, bean curd brain flower, Stigma Maydis is stewed Carnis Anodonta seu crislaria, fry bamboo sprout, the Radix Notoginseng chicken, fry bamboo sprout, the female steamed whole duck with fungus of dragon, Rhizoma Chuanxiong Radix Angelicae Dahuricae matelote head, steamed yellow chicken, winter bamboo heart sheet, the Exocarpium Citrulli sliced meat, fry three-coloured amaranth, cold and dressed with sauce Herba Portulacae, fry Fructus Momordicae charantiae, cold and dressed with sauce harmony dish, the snowflake chicken soup, the Carapax Trionycis kidney reinforcing decoction, Radix Adenophorae (Radix Glehniae) cardiopulmonary soup, silkworm chrysalis Semen Juglandis soup, the Carnis Haliotidis chicken soup, the mushroom pork liver soup, pork liver spinach soup, Folium Malvae soup, the Radix Aconiti Lateralis Preparata mutton soup, the big benefit soup of Testudinis sheep, the Fructus Benincasae pig lung decoction, sea snake Ungula Sus domestica soup, peach rake drink, the Bulbus Fritillariae Cirrhosae almond water, steam Rana nigromaculata, the baking Fructus Solani melongenae, Saut, cold and dressed with sauce Herba Houttuyniae, fry Fructus Momordicae charantiae, cold and dressed with sauce Folium Allii tuberosi, fry Herba Capsellae, cold and dressed with sauce green bud, the Flos Chrysanthemi sliced meat, cold and dressed with sauce Eucheuma gelatinosum, ground ear Canton style roast pork, the mamoncillo stewed pig's trotters, cold and dressed with sauce Herba Apii graveolentis, Gaster Sus domestica burns JIANGFU, sweet and sour garlic, Bulbus Allii Macrostemonis is stewed Cor Sus domestica, steamed golden melon, fry onion, the stomach reinforcing drink, Rhizoma Nelumbinis wheat drink, the Fructus Evodiae drink, profound wheat drink, the Fructus Averrhoae Carambolae drink, congchi tang, white tiger Ramulus Cinnamomi drink, the BAICAO drink, Fructus Pruni fiber crops drink, brave peace drink, the Ramulus Cinnamomi drink, Radix Stemonae Mel drink, ginseng stilbene drink, Flos Chrysanthemi sliced meat (silk), the biscuiting Rhizoma Solani tuber osi, Semen Ginkgo is stewed old duck, the full duck of Semen Amaranthi tricoloris, Semen Armeniacae Amarum is stewed Pulmonis Sus domestica, Bulbus Fritillariae Uninbracteatae Steamed chicken egg, stew Carnis Serpentis in clear soup, Canis familiaris L. row braised in soy sauce, the red Pedis Ursus of ginseng stilbene, heavy summer Cor Sus domestica, three core are stewed cardiopulmonary, the worm duck that rues, the full duck of Bulbus Fritillariae Uninbracteatae, Radix Raphani is burnt the lobe of the lung, the ginseng stilbene is stewed hoof, fish Rhizoma Nelumbinis stewed pig's trotters, universe steams Canis familiaris L..

Breaking cellular wall extracting method of the present invention is applicable to that also the medicated diet additive is a raw material, for example:

Rhizoma Gastrodiae, Radix Notoginseng, Radix Salviae Miltiorrhizae, Fructus Citri Sarcodactylis, Fructus Citri, Radix Aconiti Lateralis Preparata, Rhizoma Phragmitis, Semen Sterculiae Lychnophorae, Ganoderma, Poria, Hippocampus, Cordyceps, Placenta Hominis, Cornu Cervi Pantotrichum, Herba Saussureae Involueratae, Herb Gynostemmae Pentaphylli, Radix Rhodiolae, Herba Cistanches, the Cortex Eucommiae, Radix Panacis Quinquefolii, Radix Ginseng, Radix Angelicae Sinensis, Radix Rehmanniae, Colla Corii Asini, Radix Glehniae, Radix Ophiopogonis, Radix Asparagi, Herba Dendrobii, Rhizoma Polygonati Odorati, Radix Morindae Officinalis, Herba Epimedii, Fructus Ligustri Lucidi, Carapax Et Plastrum Testudinis, Carapax Trionycis, Semen Astragali Complanati, field dobber, Semen Allii Tuberosi.

In the process of heating extraction, breaking cellular wall squeezing, can be in every section operation wherein effective ingredient etc. be carried out microcomputer and monitor automatically, be the best to carry out quantitative assay again, can grasp the situation of extraction so at any time.After filtering, can also carry out quantitative effective ingredient wherein with the automatic monitoring of microcomputer to its filtrate.

In processes such as concentrating under reduced pressure, spray drying, granulation, also can monitor detection with microcomputer.The product of producing can be carried out packing by certain requirement, and can mark content of effective wherein.

In a word, in the whole process of method of the present invention, all can measure with the assay method of country's mark product, with means such as ultraviolet spectrometry spectrum, gas chromatogram, atomic absorption spectrum, thin layer chromatography, high performance liquid chromatography, capillary electrophoresis the extracting solution in the production process, press liquor, fluid extract are carried out the detection of effective ingredient, can the effective ingredient in the product be detected at last.

The advantage of the breaking cellular wall extracting method of a kind of Chinese crude drug of the present invention and prescription just is:

1. owing to adopted the breaking cellular wall Technology in Pressing in the method for the invention, mixing extraction ratio of effective constituents in Chinese crude drug and the prescription thereof is improved greatly, our experiments show that single jar of traditional extracting method only is 60～65% to mixing extraction ratio of effective constituents, and the continuous extraction method of the patent No. 00107662.0 is 72～86% to mixing extraction ratio of effective constituents, and breaking cellular wall extracting method of the present invention can reach 98% to mixing extraction ratio of effective constituents, even 100%.

2. the product made from breaking cellular wall extracting method of the present invention is convenient to take, and slows down the misery of the difficulty of taking medicine, and it is fast to have kept decoction to absorb again, and produce effects is rapid, and the short time can be brought into play the advantage of drug effect, has improved drug effect again, is more convenient for taking during the journey.

3. the medicated powder granule of producing with breaking cellular wall extracting method of the present invention invariance is not at high temperature gone mouldy.

4. because can being added to the medicinal residues fine powder, breaking cellular wall extracting method of the present invention forms the medicated powder granule in the fluid extract, increased the Plant fiber's amount in the medicine, take the medicine that contains a large amount of Plant fiber, the health that is of value to human body, strengthen the curative effect of medicine, increase coarse-fibred intake, clear up intravital free radical.

Below with embodiment breaking cellular wall extractive technique of the present invention is further described; to help method of the present invention and advantage thereof are done further to understand; protection scope of the present invention is not subjected to the qualification of these embodiment, and protection scope of the present invention is decided by claims.

Embodiment 1

With pretreated 100 kilograms of Radix Ginsengs is raw material, adds entry in the raw material Radix Ginseng, and the water yield that is added is 10 times of raw material weight, and 100 ℃ of heating extraction are 8 hours under normal pressure, obtains extracting solution and medicinal residues for the first time for the first time.To the first time medicinal residues under the pressure of 5.0 kg/cm, carry out the breaking cellular wall squeezing first time, time press liquor and of winning for the first time through the medicinal residues of squeezing.To in the medicinal residues of squeezing, adding entry for the first time, stir and make medicinal residues loose in water, the water yield that is added is 5 times of raw material weight, under normal pressure, carry out the heating extraction 4 hours second time in 95 ℃, get extracting solution and medicinal residues for the second time for the second time, to the second time medicinal residues under the pressure of 3.0 kg/cm, carry out the breaking cellular wall squeezing second time, press liquor and for the second time through the medicinal residues of squeezing for the second time.Make medicinal residues loose in water to for the second time adding entry in the medicinal residues of squeezing, stirring, the water yield that is added is 2 times of raw material weight, carries out for the third time heating extraction 2 hours under normal pressure under 60 ℃ temperature, extracting solution and medicinal residues for the third time for the third time.Medicinal residues are for the third time carried out breaking cellular wall squeezing for the third time under the pressure of 1.0 kg/cm, press liquor and medicinal residues for the third time for the third time through squeezing.

The extracting solution of three merging and the press liquor of three merging are filtered with the plate and frame filter respectively.To placing the concentrating under reduced pressure jar under 60 ℃ temperature, carrying out concentrating under reduced pressure under the pressure of pressure 0.05MPa respectively, make it be condensed into the fluid extract of proportion 1.15 through filtering extracting solution and press liquor.Merge fluid extract, mix homogeneously, its result is for containing in the fluid extract by raw material Radix Ginseng 5 grams: ginsenoside Ra38.2mg, panaxosideRb2 6.8mg, ginsenoside Rc 23.2mg, ginsenoside Rd 14.8mg, ginsenoside Rg1 6.2mg, ginsenoside Re 9.8mg, ginsenoside Ro13.6mg.Mixture effective ingredient 722.1mg.Said mixture effective ingredient is the fluid extract by raw material Radix Ginseng 5 grams, contains the weight of mixture effective ingredient after the spray drying.

Comparing embodiment 1: with single jar of extraction of tradition

With pretreated 100 kilograms of Radix Ginsengs is raw material, in raw material, add entry, the water yield that is added is 10 times of raw material weight, 100 ℃ of heating extraction are 2 hours under normal pressure, win time extracting solution of filtration, in medicinal residues, add entry, the water yield that is added is 8 times of heavy amounts of raw material, at normal pressure in 100 ℃ of heating extraction 2 hours, filter extracting solution for the second time, the extracting solution that merges secondary, under 60 ℃ temperature, carrying out concentrating under reduced pressure under the pressure of pressure 0.05MPa, make its fluid extract that is condensed into proportion 1.15, contain in the fluid extract of its result by raw material Radix Ginseng 5 grams: ginsenoside Ra20.2mg, ginsenoside Rb1 6.3mg, ginsenoside Rc 14.6mg, ginsenoside Rd 10.4mg, ginsenoside Rg1 1.8mg, ginsenoside Re 6.4mg, ginsenoside Ro8.8mg.Mixture effective ingredient 440.5mg.

Comparing embodiment one: the continuous extraction with application number 00107662.0 extracts.

With pretreated 100 kilograms of Radix Ginsengs is raw material, adds entry in raw material, and the water yield that is added is 10 times of raw material weight, in 100 ℃ of heating extraction 8 hours, obtains extracting solution and medicinal residues for the first time for the first time under normal pressure.Add entry to the first time in the medicinal residues, the water that is added is 5 times of raw material weight, carries out the heating extraction 4 hours second time in 95 ℃ under normal pressure, extracting solution and medicinal residues for the second time for the second time.Add entry to the second time in the medicinal residues, the water yield that is added is 2 times of material quantity, under normal pressure, under 60 ℃ temperature, carried out for the third time heating extraction 2 hours, get extract and medicinal residues for the third time for the third time, merge first, two, three extracting solution, filter, in the concentrating under reduced pressure jar,, under 60 ℃ temperature, carry out concentrating under reduced pressure in 0.05MPa, make it be condensed into the fluid extract of proportion 1.15, contain in the fluid extract of its result by Radix Ginseng 5 grams: ginsenoside Ra27.6mg, panaxosideRb2 1.6mg, ginsenoside Rc 18.9mg, ginsenoside Rd 12.4mg, ginsenoside Rg1 3.5mg, ginsenoside Re 7.6mg, ginsenoside Ro11.3mg.Mixture effective ingredient 577.7mg.

Embodiment 2

Its operational approach and equipment is substantially with embodiment 1, and only different is with pretreated 100 kilograms of Radix Polygoni Multiflori is raw material, and the water yield that adds in raw material is 4 times of raw material weight, won in 8 hours time extracting solution and medicinal residues for the first time of 60 ℃ of heating extraction under normal pressure.To the first time medicinal residues carry out win time press liquor and of breaking cellular wall squeezing for the first time in the pressure of 5.0 kg/cm for the first time through the medicinal residues of squeezing.To the water yield that adds in the medicinal residues of squeezing for the first time is 8 times of raw material weight, carries out heating extraction 6 hours second time in 95 ℃, for the second time extracting solution and the second time medicinal residues.To the second time medicinal residues under the pressure of 5 kg/cm, carry out the breaking cellular wall squeezing second time, press liquor and for the second time through the medicinal residues of squeezing for the second time.The water yield that adds in the medicinal residues of squeezing to the second time is 6 times of raw material weight, carried out for the third time heating extraction 4 hours in 65 ℃, get extracting solution and medicinal residues for the third time for the third time, medicinal residues are for the third time carried out breaking cellular wall squeezing for the third time under the pressure of 4 kg/cm, press liquor and medicinal residues for the third time for the third time through squeezing.

The extracting solution of three merging and the press liquor of three merging are mixed, filter, under the pressure of 0.03MPa, become the fluid extract of proportion 1.20, contain in the fluid extract of its result by raw material Radix Polygoni Multiflori 5 grams: lecithin 7mg at 35 ℃ of concentrating under reduced pressure, chrysophanol 17mg, emodin 15mg, physcione 20mg, emodin 1,6-dimethyl ether 10mg, ω-hydroxyemodin 12mg, chrysophanic acid anthrone 30mg, wine plant glycoside 70mg.Mixture effective ingredient 868.0mg.

With nitrogen is atomization gas, and the pressure of atomization gas is that 0.6MPa carries out spray drying, sprays into temperature and is in 200 ℃ the hot-air, forms the granule of medicated powder average diameter of particles 1500 μ m, water content 3.7% percetage by weight.

Single jar of extraction of comparing embodiment 2 usefulness tradition

Its operational approach and device and comparing embodiment 1 are basic identical, and only different is to be raw material with the Radix Polygoni Multiflori, under the pressure of 0.03MPa, become the fluid extract of proportion 1.20 at 35 ℃ of concentrating under reduced pressure, contain in the fluid extract of its result by raw material Radix Polygoni Multiflori 5 grams: lecithin 4.2mg, chrysophanol 10.5mg, emodin 9.3mg, physcione 12.1mg, emodin 1,6-dimethyl ether 6.3mg, ω-hydroxyemodin 7.1mg, chrysophanic acid anthrone 18.2mg, wine plant glycoside 42.3mg.Mixture effective ingredient 529.5mg.

Comparing embodiment two: the continuous extraction with application number 00107662.0 extracts.

Its operational approach and device and comparing embodiment one are basic identical, only different is that raw material is a Radix Polygoni Multiflori, but temperature, the time of three amount of water and heating extraction, it is identical to concentrate pressure and temperature and embodiment 2, do not carry out the breaking cellular wall squeezing after the heating extraction, contain in the fluid extract of its result by raw material Radix Polygoni Multiflori 5 grams: lecithin 5.6mg, chrysophanol 13.8mg, emodin 12.3mg, physcione 15.9mg, emodin 1,6-dimethyl ether 8.2mg, ω-hydroxyemodin 9.6mg, chrysophanic acid anthrone 24.1mg, wine plant glycoside 56.3mg.Mixture effective ingredient 694.4mg.

Embodiment 3

Its operational approach and equipment are substantially with embodiment 1, only different is with 100 kilograms of pretreated Cortex Cinnamomis is raw material, the water yield that adds in raw material is 7 times of raw material weight, 65 ℃ of heating extraction of normal pressure 6 hours, to the first time medicinal residues under the pressure of 3.5 kg/cm, carry out the breaking cellular wall squeezing first time.To the water yield that adds in the medicinal residues of squeezing for the first time is 5 times of material quantity, carries out heating extraction 4 hours second time in 90 ℃, to the second time medicinal residues under the pressure of 4 kg/cm, carry out second time breaking cellular wall and squeeze.To the water yield that adds in the medicinal residues of squeezing for the second time is 4 times of material quantity, carries out heating extraction 3 hours in 55 ℃, and medicinal residues are for the third time carried out breaking cellular wall squeezing for the third time under the pressure of 2 kg/cm.

The extracting solution of three merging and the press liquor of three merging are filtered respectively, in 0.07MPa, become the fluid extract of proportion 1.10 at 75 ℃ of concentrating under reduced pressure, merge fluid extract, mix, contain cinnamic aldehyde 56.2mg in the fluid extract of its result by raw material Cortex Cinnamomi 5 grams, cinnamic acid 9.7mg, acetic acid Cortex cinnamomi japonici (Ramulus Cinnamomi) ester 23.8mg, phenylpropyl acetate 13.4mg, benzaldehyde 37.9mg.Mixture effective ingredient 377.7mg.

To under 90 ℃ temperature, carry out drying through the medicinal residues of squeezing for the third time, exsiccant medicinal residues were ground into 160 orders, with the mistake 160 purpose medicinal residues fine powders of medicinal residues total amount 15% and the fluid extract mix homogeneously of proportion 1.10, with the compressed air is that atomization gas carries out spray drying, the pressure of spray gas is 0.9MPa, and it is the medicated powder granule that forms average diameter 2000 μ m in 170 ℃ the hot-air that the mixture of fluid extract and medicinal residues fine powder is injected to temperature.

Single jar of extraction of comparing embodiment 3 usefulness tradition

Its operational approach and device and comparing embodiment 1 are basic identical, only different is, with the Cortex Cinnamomi is that raw material is under the pressure of 0.07MPa, become the fluid extract of proportion 1.10 at 75 ℃ of concentrating under reduced pressure, contain in the fluid extract of its result by raw material Cortex Cinnamomi 5 grams: cinnamic aldehyde 36.2mg, cinnamic acid 5.9mg, acetic acid Cortex cinnamomi japonici (Ramulus Cinnamomi) ester 14.2mg, phenylpropyl acetate 7.8mg, benzaldehyde 22.3mg.Mixture effective ingredient 230.4mg.

Comparing embodiment three: the continuous extraction with application number 00107662.0 extracts.

Its operational approach and device and comparing embodiment one are basic identical, only different is that raw material is a Cortex Cinnamomi, the temperature of three amount of water and three heating extraction, time and embodiment 3 are identical, do not carry out the breaking cellular wall squeezing after each heating extraction, contain in the fluid extract of its result by raw material Cortex Cinnamomi 5 grams: cinnamic aldehyde 48.2mg, cinnamic acid 7.8mg, acetic acid Cortex cinnamomi japonici (Ramulus Cinnamomi) ester 18.6mg, phenylpropyl acetate 10.5mg, benzaldehyde 28.6mg.Mixture effective ingredient 302.2mg.

Embodiment 4

Its operational approach and equipment are substantially with embodiment 1, only different is with 100 kilograms the Rhizoma Pinelliae after the pretreatment is raw material, contain in the fluid extract of its result by the raw material Rhizoma Pinelliae 5 grams: choline 120mg, cupreol-D-glycoside 30mg, ephedrine 25mg, cupreol 10mg, pinellin 17.4mg, homogentisic acid 37mg, coniine 12mg.Mixture effective ingredient 882.4mg.

Comparing embodiment 4

Its operational approach and equipment and comparing embodiment 1 are basic identical, only different is, with the Rhizoma Pinelliae is raw material, contain in the fluid extract of its result by the raw material Rhizoma Pinelliae 5 grams: choline 72mg, cupreol-D-glycoside 18mg, ephedrine 15.3mg, cupreol 6mg, pinellin 10.2mg, homogentisic acid 21.2mg, coniine 7.3mg.Mixture effective ingredient 538.2mg.

Comparing embodiment four

Its operational approach and device and comparing embodiment one are basic identical, only different is, with the Rhizoma Pinelliae is raw material, contain in the fluid extract of its result by the raw material Rhizoma Pinelliae 5 grams: choline 96mg, cupreol-D-glycoside 24mg, ephedrine 19.8mg, cupreol 8mg, pinellin 13.8mg, homogentisic acid 29.6mg, coniine 9.6mg.Mixture effective ingredient 705.9mg.

Embodiment 5

Its operational approach and equipment are substantially with embodiment 1, only different is with 100 kilograms Flos Caryophylli after the pretreatment is raw material, contain in the fluid extract of its result by raw material Flos Caryophylli 5 grams: eugenol 6.4mg, Flos Caryophylli alkene 43.8mg, aceteugenol 46.2mg, methyl salicylate 19.7mg, benzaldehyde 1.47mg, epoxy Flos Caryophylli alkene 6.1mg, α-selinene 23.1mg.Mixture effective ingredient 552.3mg.

Comparing embodiment 5

Its operational approach and equipment and comparing embodiment 1 are basic identical, only different is, with the Flos Caryophylli is raw material, contain in the fluid extract of its result by raw material Flos Caryophylli 5 grams: eugenol 3.8mg, Flos Caryophylli alkene 26.3mg, aceteugenol 28.1mg, methyl salicylate 11.8mg, benzaldehyde 0.8mg, epoxy Flos Caryophylli alkene 3.7mg, α-selinene 13.8mg.Mixture effective ingredient 336.9mg.

Comparing embodiment five

Its operational approach and device and comparing embodiment one are basic identical, only different is, with the Flos Caryophylli is raw material, contain in the fluid extract of its result by raw material Flos Caryophylli 5 grams: eugenol 5.1mg, Flos Caryophylli alkene 35.2mg, aceteugenol 36.2mg, methyl salicylate 16.8mg, benzaldehyde 1.2mg, epoxy Flos Caryophylli alkene 4.8mg, α-selinene 18.6mg.Mixture effective ingredient 441.8mg.

Embodiment 6

Its operational approach and equipment are substantially with embodiment 1, only different is with 100 kilograms the Rhizoma Anemarrhenae after the pretreatment is raw material, contains in the fluid extract of its result by the raw material Rhizoma Anemarrhenae 5 grams: zhimusaponin 12.1mg, Mengiferin 8.2mg, isomangiferin 10.5mg contains anemaran 23.5mg.Mixture effective ingredient 961.7mg.

Comparing embodiment 6

Its operational approach and equipment are basic with comparing embodiment 1, only different is with pretreated 100 kilograms of Rhizoma Anemarrhenaes is raw material, contains in the fluid extract of its result by the raw material Rhizoma Anemarrhenae 5 grams: zhimusaponin 8.3mg, Mengiferin 6.5mg, isomangiferin 8.6mg contains anemaran 16.5mg.Mixture effective ingredient 586.6mg.

Comparing embodiment six

Its operational approach and equipment and comparing embodiment one are basic identical, and only different is to be raw material with pretreated 100 kilograms of Rhizoma Anemarrhenaes, contain in the fluid extract of its result by the raw material Rhizoma Anemarrhenae 5 grams: zhimusaponin 9.2mg, Mengiferin 7.1mg, isomangiferin 9.3mg contains anemaran 19.8mg.Mixture effective ingredient 769.4mg.

Embodiment 7

Its operational approach and equipment are substantially with embodiment 1, only different is with 100 kilograms of SEMEN COICIS after the pretreatment is raw material, contain in the fluid extract of its result by raw material SEMEN COICIS 5 grams: nutmeg acid 10.2mg Semen Coicis fat 8.5mg, Coixol 9.6mg, Resina Ferulae acyl stigmasterol 6mg.Mixture effective ingredient 1277.7mg

Comparing embodiment 7

Its operational approach and equipment and comparing embodiment 1 are basic identical, and only different is to be raw material with pretreated 100 kilograms of SEMEN COICIS, contain in the fluid extract of its result by raw material SEMEN COICIS 5 grams: nutmeg acid 6.1mg, Semen Coicis fat 5.2mg, Coixol 5.8mg, Resina Ferulae acyl stigmasterol 3.6mg.Mixture effective ingredient 779.4mg.

Comparing embodiment seven

Its operational approach and equipment and comparing embodiment one are basic identical, only different is with pretreated 100 kilograms of SEMEN COICIS is raw material, contains in the fluid extract of its result by raw material SEMEN COICIS 5 grams: nutmeg acid 8.1mg, Semen Coicis fat 6.5mg, Coixol 7.6mg, Resina Ferulae acyl stigmasterol 4.8mg.Mixture effective ingredient 1022.2mg.

Embodiment 8

Its operational approach and equipment is substantially with embodiment 1, and only different is with 100 kilograms of Radixs Angelicae Dahuricae after the pretreatment is raw material, contains in the fluid extract of its result by the raw material Radix Angelicae Dahuricae 5 grams: white Radix Angelicae Sinensis ether 9.7mg, elemene 24.2mg, isoimperatorin 8.7mg, ethyl laurate 54.3mg, peonol 11.6mg.Mixture effective ingredient 877.5mg.

Comparing embodiment 8

Its operational approach and equipment are basic with comparing embodiment 1, only different is with pretreated 100 kilograms of Radixs Angelicae Dahuricae is raw material, contain in the fluid extract of its result by the raw material Radix Angelicae Dahuricae 5 grams: white Radix Angelicae Sinensis ether 5.8mg, elemene 14.2mg, isoimperatorin 5.7mg, ethyl laurate 35.6mg, peonol 7.1mg.Mixture effective ingredient 535.3mg.

Comparing embodiment eight

Its operational approach and equipment are basic with comparing embodiment one, only different is with pretreated 100 kilograms of Radixs Angelicae Dahuricae is raw material, contain in the fluid extract of its result by the raw material Radix Angelicae Dahuricae 5 grams: white Radix Angelicae Sinensis ether 7.9mg, elemene 16.5mg, isoimperatorin 6.8mg, ethyl laurate 42.3mg, peonol 8.6mg.Mixture effective ingredient 702.0mg.

Embodiment 9

Its operational approach and equipment are substantially with embodiment 1, only different is with the raw material of acting like a bully of 100 kilograms of units after the pretreatment, contains in the fluid extract of its result by raw material Rhizoma Corydalis 5 grams: tetrahydropalmatine 6.9mg, the plain 4.6mg of Rhizoma Corydalis first, corydalis 8.2mg, the plain 3.2mg of dehydrogenation Rhizoma Corydalis first.Mixture effective ingredient 827.6mg.

Comparing embodiment 9

Its operational approach and equipment are basic with comparing embodiment 1, only different is with pretreated 100 kilograms of units raw material of acting like a bully, contain in the fluid extract of its result by raw material Rhizoma Corydalis 5 grams: tetrahydropalmatine 4.2mg, the plain 2.8mg of Rhizoma Corydalis first, corydalis 5.2mg, the plain 2.1mg of dehydrogenation Rhizoma Corydalis first.Mixture effective ingredient 504.8mg.

Comparing embodiment nine

Its operational approach and equipment are basic with comparing embodiment one, only different is with pretreated 100 kilograms of units raw material of acting like a bully, contain in the fluid extract of its result by raw material Rhizoma Corydalis 5 grams: tetrahydropalmatine 5.6mg, the plain 3.7mg of Rhizoma Corydalis first, corydalis 6.5mg, the plain 2.5mg of dehydrogenation Rhizoma Corydalis first.Mixture effective ingredient 662.1mg.

Embodiment 10

Its operational approach and equipment is substantially with embodiment 1, and only different is with pretreated 100 kilograms of Radix Aucklandiae is raw material, contains in the fluid extract of its result by the raw material Radix Aucklandiae 5 grams: costic acid 3.2mg, costol 5.6mg, constuslactone 4.8mg contains stigmasterol and resin, and several amino acids.Mixture effective ingredient 1472.1mg.

Comparing embodiment 10

Its operational approach and equipment are basic with embodiment 1 relatively, and only different is with pretreated 100 kilograms of Radix Aucklandiae is raw material, contains in the fluid extract of its result by the raw material Radix Aucklandiae 5 grams: costic acid 2.1mg, costol 3.4mg, constuslactone 2.8mg contains stigmasterol and resin, and several amino acids.Mixture effective ingredient 897.9mg.

Comparing embodiment ten

Its operational approach and equipment are basic with embodiment one relatively, and only different is with pretreated 100 kilograms of Radix Aucklandiae is raw material, contains in the fluid extract of its result by the raw material Radix Aucklandiae 5 grams: costic acid 2.5mg, costol 4.6mg, constuslactone 3.9mg contains stigmasterol and resin, and several amino acids.Mixture effective ingredient 1162.9mg.

Embodiment 11

Its operational approach and equipment is substantially with embodiment 1, and only different is with pretreated 100 kilograms of Rhizoma Et Radix Notopterygiis is raw material, contains in the fluid extract of its result by raw material Rhizoma Et Radix Notopterygii 5 grams: bergapten 5.8mg, decuroside 6.6mg, isoimperatorin 4.2mg.Mixture effective ingredient 1159.6mg.

Comparing embodiment 11

Its operational approach and equipment are basic with embodiment 1 relatively, and only different is with pretreated 100 kilograms of Rhizoma Et Radix Notopterygiis is raw material, contains in the fluid extract of its result by raw material Rhizoma Et Radix Notopterygii 5 grams: bergapten 3.5mg, decuroside 3.9mg, isoimperatorin 2.5mg.Mixture effective ingredient 707.3mg.

Comparing embodiment 11

Its operational approach and equipment are basic with embodiment one relatively, and only different is with pretreated 100 kilograms of Rhizoma Et Radix Notopterygiis is raw material, contains in the fluid extract of its result by raw material Rhizoma Et Radix Notopterygii 5 grams: bergapten 4.7mg, decuroside 5.2mg, isoimperatorin 3.4mg.Mixture effective ingredient 916.0mg.

Embodiment 12

Its operational approach and equipment are substantially with embodiment 1, only different is with 100 kilograms Herba Menthae after the pretreatment is raw material, contain in the fluid extract of its result by raw material Herba Menthae 5 grams: menthone 3.2mg, lotus protocerebrum archicerebrum 2.6mg, luteolin 4.1mg, leaf is along containing threonine, alanine, glutamic acid, day then multiple free amino acid such as amide.Zinc, ferrum, manganese, copper, chromium, the multiple metallic element of nickel.Mixture effective ingredient 979.1mg.

Comparing embodiment 12

Its operational approach and equipment are basic with comparing embodiment 1, only different is with pretreated 100 kilograms of Herba Menthaes is raw material, contain in the fluid extract of its result by raw material Herba Menthae 5 grams: menthone 2.1mg, lotus protocerebrum archicerebrum 1.7mg, luteolin 2.6mg, leaf is along containing threonine, alanine, glutamic acid, day then multiple free amino acid such as amide.Zinc, ferrum, manganese, copper, chromium, the multiple metallic element of nickel.Mixture effective ingredient 597.19mg.

Comparing embodiment 12

Its operational approach and equipment are basic with comparing embodiment one, only different is with pretreated 100 kilograms of Herba Menthaes is raw material, contain in the fluid extract of its result by raw material Rhizoma Et Radix Notopterygii 5 grams: menthone 2.5mg, lotus protocerebrum archicerebrum 2.1mg, luteolin 3.4mg, leaf is along containing threonine, alanine, glutamic acid, day then multiple free amino acid such as amide.Zinc, ferrum, manganese, copper, chromium, the multiple metallic element of nickel.Mixture effective ingredient 773.41mg.

Embodiment 13

Its operational approach and equipment are substantially with embodiment 1, only different is with pretreated 100 kilograms of Semen Ziziphi Spinosaes is raw material, contains in the fluid extract of its result by raw material acid Semen Ziziphi Spinosae 5 grams: Semen Ziziphi Spinosae saponin 6.2mg, flavonoid glycoside 3.8mg, swertisin 4.2mg, betulinic acid 2.6mg.Mixture effective ingredient 983.6mg.

Comparing embodiment 13

Its operational approach and equipment are basic with comparing embodiment 1, only different is with 100 kilograms Semen Ziziphi Spinosae after the pretreatment is raw material, contains in the fluid extract of its result by raw material acid Semen Ziziphi Spinosae 5 grams: Semen Ziziphi Spinosae saponin 4.3mg, flavonoid glycoside 2.2mg, swertisin 2.8mg, betulinic acid 1.6mg.Mixture effective ingredient 599.63mg.

Comparing embodiment 13

Its operational approach and equipment are basic with comparing embodiment one, only different is with pretreated 100 kilograms of Semen Ziziphi Spinosaes is raw material, contains in the fluid extract of its result by raw material acid Semen Ziziphi Spinosae 5 grams: Semen Ziziphi Spinosae saponin 5.1mg, flavonoid glycoside 2.9mg, swertisin 3.6mg, betulinic acid 2.1mg.Mixture effective ingredient 776.57mg.

Embodiment 14

Its operational approach and equipment are substantially with embodiment 1, only different is with 100 kilograms Folium Perillae after the pretreatment is raw material, contains in the fluid extract of its result by raw material Folium Perillae 5 grams: perillaldehyde 3.2mg, australene 2.2mg, d-limonene 3.1mg, 1-linalool 1.6mg.Mixture effective ingredient 1322.5mg.

Comparing embodiment 14

Its operational approach and equipment are basic with comparing embodiment 1, only different is with pretreated 100 kilograms of Folium Perillaes is raw material, contains in the fluid extract of its result by raw material Folium Perillae 5 grams: perillaldehyde 2.1mg, australene 1.4mg, d-limonene 1.8mg, 1-linalool 1.2mg.Mixture effective ingredient 806.7mg.

Comparing embodiment 14

Its operational approach and equipment are basic with comparing embodiment one, only different is with pretreated 100 kilograms of Folium Perillaes is raw material, contains in the fluid extract of its result by raw material Folium Perillae 5 grams: perillaldehyde 2.6mg, australene 1.7mg, d-limonene 2.4mg, 1-linalool 1.3mg.Mixture effective ingredient 1044.7mg.

Embodiment 15

Its operational approach and equipment is substantially with embodiment 1, and only different is with 100 kilograms of Radix Puerariaes after the pretreatment is raw material, contains in the fluid extract of its result by raw material Radix Puerariae 5 grams: daidzin 3.2mg, puerarin 4.8mg, allantoin 3.9mg, cupreol 2.6mg, daucosterol 5.6mg.Mixture effective ingredient 860.3mg.

Comparing embodiment 15

Its operational approach and equipment are basic with embodiment 1 relatively, and only different is with pretreated 100 kilograms of Radix Puerariaes is raw material, contains in the fluid extract of its result by raw material Radix Puerariae 5 grams: daidzin 2.1mg, puerarin 2.8mg, allantoin 2.3mg, cupreol 1.5mg, daucosterol 3.4mg.Mixture effective ingredient 524.7mg.

Comparing embodiment 15

Its operational approach and equipment are basic with embodiment one relatively, and only different is with pretreated 100 kilograms of Radix Puerariaes is raw material, contains in the fluid extract of its result by raw material Radix Puerariae 5 grams: daidzin 2.5mg, puerarin 3.8mg, allantoin 3.1mg, cupreol 2.1mg, daucosterol 4.5mg.Mixture effective ingredient 679.6mg.

Embodiment 16

Its operational approach and equipment is substantially with embodiment 1, and only different is with pretreated 100 kilograms of Herba Epimedii is raw material, contains in the fluid extract of its result by raw material Herba Epimedii 5 grams: Herba Epimedii glycoside 3.4mg, Quercetin 5.2mg, the new glycoside 4.1mg of Herba Epimedii.The mixture effective ingredient is 1221.3mg.

Comparing embodiment 16

Its operational approach and equipment are basic with embodiment 1 relatively, and only different is with pretreated 100 kilograms of Herba Epimedii is raw material, contains in the fluid extract of its result by raw material Herba Epimedii 5 grams: Herba Epimedii glycoside 2.2mg, Quercetin 3.2mg, the new glycoside 2.5mg of Herba Epimedii.The mixture effective ingredient is 744.9mg.

Comparing embodiment 16

Its operational approach and equipment are basic with embodiment one relatively, and only different is with pretreated 100 kilograms of Radix Puerariaes is raw material, contains in the fluid extract of its result by raw material Radix Puerariae 5 grams: Herba Epimedii glycoside 2.8mg, Quercetin 4.2mg, the new glycoside 3.2mg of Herba Epimedii.Mixture effective ingredient 964.8mg.

Embodiment 17

Its operational approach and equipment is substantially with embodiment 1, and only different is with pretreated 100 kilograms of Polyporus is raw material, contains in the fluid extract of its result by raw material Polyporus 5 grams: lysergol 6.2mg, crude protein 7.8mg, polyporusum bellatus 12.5mg, Polyporus ketone 3.5mg.The mixture effective ingredient is 723.8mg.

Comparing embodiment 17

Its operational approach and equipment are basic with comparing embodiment 1, only different is with pretreated 100 kilograms of Polyporus is raw material, contains in the fluid extract of its result by raw material Polyporus 5 grams: lysergol 3.7mg, crude protein 4.8mg, polyporusum bellatus 7.5mg, Polyporus ketone 2.1mg.The mixture effective ingredient is 441.5mg.

Comparing embodiment 17

Its operational approach and equipment are basic with comparing embodiment one, only different is with pretreated 100 kilograms of Polyporus is raw material, contains in the fluid extract of its result by raw material Polyporus 5 grams: lysergol 5.1mg, crude protein 6.2mg, polyporusum bellatus 10.2mg, Polyporus ketone 2.8mg.The mixture effective ingredient is 571.8mg.

Embodiment 18

Its operational approach and equipment are substantially with embodiment 1, only different is with 100 kilograms of Cortex Magnoliae Officinalis of pretreatment is raw material, contain in the fluid extract of its result by raw material Cortex Magnoliae Officinalis 5 grams: magnolol 3.2mg, honokiol 5.6mg, eudesmol 2.1mg, australene 3.1mg, camphene 1.2mg, magnocurarine 1.1mg, magnoflorine 1.3mg.The mixture effective ingredient is 776.6mg.

Comparing embodiment 18

Its operational approach and equipment are basic with comparing embodiment 1, only different is with pretreated 100 kilograms of Cortex Magnoliae Officinalis is raw material, contain in the fluid extract of its result by raw material Cortex Magnoliae Officinalis 5 grams: magnolol 1.9mg, honokiol 3.4mg, eudesmol 1.3mg, australene 1.8mg, camphene 0.7mg, magnocurarine 0.7mg, magnoflorine 0.9mg.The mixture effective ingredient is 473.7mg.

Comparing embodiment 18

Its operational approach and equipment are basic with comparing embodiment one, only different is with pretreated 100 kilograms of Cortex Magnoliae Officinalis is raw material, contain in the fluid extract of its result by raw material Cortex Magnoliae Officinalis 5 grams: magnolol 2.6mg, honokiol 4.5mg, eudesmol 1.7mg, australene 2.5mg, camphene 0.9mg, magnocurarine 0.9mg, magnoflorine 1.1mg.The mixture effective ingredient is 613.5mg.

Embodiment 19

Its operational approach and equipment is substantially with embodiment 1, and only different is with 100 kilograms of Radix Scutellariaes of pretreatment is raw material, contains in the fluid extract of its result by raw material Radix Scutellariae 5 grams: baicalin 3.6mg, chrysin 4.1mg, oroxylin 4.5mg, wogonoside 6.4mg, neobaicalein 5.2mg.The mixture effective ingredient is 873.5mg.

Comparing embodiment 19

Its operational approach and equipment are basic with comparing embodiment 1, only different is with pretreated 100 kilograms of Radix Scutellariaes is raw material, contain in the fluid extract of its result by raw material Radix Scutellariae 5 grams: baicalin 2.1mg, chrysin 2.5mg, oroxylin 2.7mg, wogonoside 3.8mg, neobaicalein 3.2mg.The mixture effective ingredient is 532.8mg.

Comparing embodiment 19

Its operational approach and equipment are basic with comparing embodiment one, only different is with pretreated 100 kilograms of Radix Scutellariaes is raw material, contain in the fluid extract of its result by raw material Radix Scutellariae 5 grams: baicalin 2.8mg, chrysin 3.3mg, oroxylin 3.6mg, wogonoside 5.2mg, neobaicalein 4.2mg.The mixture effective ingredient is 690.0mg.

Embodiment 20

Its operational approach and equipment are substantially with embodiment 1, only different is with 100 kilograms of Flos Chrysanthemis of pretreatment is raw material, contain in the fluid extract of its result by raw material Flos Chrysanthemi 5 grams: Camphora 1.2mg, 1,8-Oleum Eucalypti ether β Flos Caryophylli alkene 2.3mg, Borneolum Syntheticum 2.5mg, borneol acetate 0.8mg, farnesol 1.2mg, alpha-terpineol 1.8mg.The mixture effective ingredient is 798.5mg.

Comparing embodiment 20

Its operational approach and equipment are basic with comparing embodiment 1, only different is with pretreated 100 kilograms of Flos Chrysanthemis is raw material, contain in the fluid extract of its result by raw material Flos Chrysanthemi 5 grams: Camphora 0.7mg, 1,8-Oleum Eucalypti ether β Flos Caryophylli alkene 1.8mg, Borneolum Syntheticum 1.5mg, borneol acetate 0.5mg, farnesol 0.7mg, alpha-terpineol 1.2mg.The mixture effective ingredient is 487.0mg.

Comparing embodiment 20

Its operational approach and equipment are basic with comparing embodiment one, only different is with pretreated 100 kilograms of Flos Chrysanthemis is raw material, contain in the fluid extract of its result by raw material Flos Chrysanthemi 5 grams: Camphora 0.9mg, 1,8-Oleum Eucalypti ether β Flos Caryophylli alkene 1.8mg, Borneolum Syntheticum 2mg, borneol acetate 0.6mg, farnesol 0.9mg, alpha-terpineol 1.5mg.The mixture effective ingredient is 630.8mg.

Embodiment 21

Its operational approach and equipment is substantially with embodiment 1, and only different is with 100 kilograms of pretreated Radix Codonopsis is raw material, contains in the fluid extract of its result by raw material Radix Codonopsis 5 grams: Radix Codonopsis Saponin 13.6mg, inulin 22.5mg, plant sterol 6.3mg, polysaccharide 16.35mg, choline 8.18mg.The mixture effective ingredient is 732.3mg.

Comparing embodiment 21

Its operational approach and equipment are basic with embodiment 1 relatively, and only different is with pretreated 100 kilograms of Radix Codonopsis is raw material, contains in the fluid extract of its result by raw material Radix Codonopsis 5 grams: Radix Codonopsis Saponin 8.2mg, inulin 13.6mg, plant sterol 3.7mg, polysaccharide 9.97mg, choline 4.99mg.The mixture effective ingredient is 446.7mg.

Comparing embodiment 21

Its operational approach and equipment are basic with embodiment one relatively, and only different is with pretreated 100 kilograms of Radix Codonopsis is raw material, contains in the fluid extract of its result by raw material Radix Codonopsis 5 grams: Radix Codonopsis Saponin 11.2mg, inulin 18.5mg, plant sterol 5.2mg, polysaccharide 13.08mg, choline 6.55mg.The mixture effective ingredient is 578.5mg.

Embodiment 22

Its operational approach and equipment is substantially with embodiment 1, and only different is with 100 kilograms of pretreated Radix Gentianae Macrophyllae is raw material, contains in the fluid extract of its result by raw material Radix Gentianae Macrophyllae 5 grams: Radix Gentianae Macrophyllae alkali 6.5mg, gentiopicrin 5.8mg.The mixture effective ingredient is 842.6mg.

Comparing embodiment 22

Its operational approach and equipment are basic with embodiment 1 relatively, and only different is with pretreated 100 kilograms of Radix Gentianae Macrophyllae is raw material, contains in the fluid extract of its result by raw material Radix Gentianae Macrophyllae 5 grams: Radix Gentianae Macrophyllae alkali 3.9mg, gentiopicrin 3.5mg.The mixture effective ingredient is 513.9mg.

Comparing embodiment 22

Its operational approach and equipment are basic with embodiment one relatively, and only different is with pretreated 100 kilograms of Radix Gentianae Macrophyllae is raw material, contains in the fluid extract of its result by raw material Radix Gentianae Macrophyllae 5 grams: Radix Gentianae Macrophyllae alkali 5.2mg, gentiopicrin 4.5mg.The mixture effective ingredient is 665.6mg.

Embodiment 23

Its operational approach and equipment is substantially with embodiment 1, and only different is with 100 kilograms of pretreated Cortex Phellodendris is raw material, contains in the fluid extract of its result by raw material Cortex Phellodendri 5 grams: berberine 6.2mg, phellodendrine 3.8mg, obacunone 4.8mg, obakulactone 5.2mg.The mixture effective ingredient is 723.7mg.

Comparing embodiment 23

Its operational approach and equipment are basic with comparing embodiment 1, only different is with pretreated 100 kilograms of Cortex Phellodendris is raw material, contains in the fluid extract of its result by raw material Cortex Phellodendri 5 grams: berberine 3.9mg, phellodendrine 2.2mg, obacunone 2.9mg, obakulactone 3.2mg.The mixture effective ingredient is 441.4mg.

Comparing embodiment 23

Its operational approach and equipment are basic with comparing embodiment one, only different is with pretreated 100 kilograms of Cortex Phellodendris is raw material, contains in the fluid extract of its result by raw material Cortex Phellodendri 5 grams: berberine 4.8mg, phellodendrine 2.8mg, obacunone 3.8mg, obakulactone 4.2mg.The mixture effective ingredient is 571.7mg.

Embodiment 24

Its operational approach and equipment is substantially with embodiment 1, and only different is with 100 kilograms of pretreated Radix Adenophoraes is raw material, contains in the fluid extract of its result by raw material Radix Adenophorae 5 grams: Pu Gonghuang match ketone 4.5mg, triterpene saponin 6.2mg, ligustrin 5.4mg.The mixture effective ingredient is 725.1mg.

Comparing embodiment 24

Its operational approach and equipment are basic with comparing embodiment 1, only different is with pretreated 100 kilograms of Radix Adenophoraes is raw material, contain in the fluid extract of its result by raw material Radix Adenophorae 5 grams: Pu Gonghuang match ketone 2.8mg, triterpene saponin 3.7mg, ligustrin 3.2mg.The mixture effective ingredient is 442.3mg.

Comparing embodiment 24

Its operational approach and equipment are basic with comparing embodiment one, only different is with pretreated 100 kilograms of Radix Adenophoraes is raw material, contain in the fluid extract of its result by raw material Radix Adenophorae 5 grams: Pu Gonghuang match ketone 3.6mg, triterpene saponin 4.8mg, ligustrin 4.3mg.The mixture effective ingredient is 572.8mg.

Embodiment 25

Its operational approach and equipment are substantially with embodiment 1; only different is with pretreated 100 kilograms Fructus Gardeniae is raw material; contain in the fluid extract of its result by raw material Fructus Gardeniae 5 grams: contain gardenoside 37.2mg; gardenoside 61.4mg; shanzhiside 54.8mg, gardoside 37.2mg, fevervine time glycoside methyl ester 23.5mg; deacetylate Herba Plantaginis methyl oxalate 74.9mg, geniposidic acid 21.8mg.The mixture effective ingredient is 729.5mg.

Comparing embodiment 25

Its operational approach and equipment are basic with comparing embodiment 1; only different is with pretreated 100 kilograms of Fructus Gardeniaes is raw material; contain in the fluid extract of its result by raw material Fructus Gardeniae 5 grams: contain gardenoside 58.6mg; gardenoside 39.6mg; shanzhiside 36.2mg, gardoside 19.6mg, fevervine time glycoside methyl ester 14.6mg; deacetylate Herba Plantaginis methyl oxalate 46.3mg, geniposidic acid 14.6mg.The mixture effective ingredient is 444.9mg.

Comparing embodiment 25

Its operational approach and equipment are basic with comparing embodiment one; only different is with pretreated 100 kilograms of Fructus Gardeniaes is raw material; contain in the fluid extract of its result by raw material Fructus Gardeniae 5 grams: contain gardenoside 78.3mg; gardenoside 50.2mg; shanzhiside 43.6mg, gardoside 30.6mg, fevervine time glycoside methyl ester 19.6mg; deacetylate Herba Plantaginis methyl oxalate 62.3mg, geniposidic acid 17.2mg.The mixture effective ingredient is 576.3mg.

Embodiment 26

Its operational approach and equipment is substantially with embodiment 1, and only different is with 100 kilograms of pretreated Fructus Aurantii Immaturuss is raw material, contains in the fluid extract of its result by raw material Fructus Aurantii Immaturus 5 grams: hesperidin 5.8mg, neohesperidin 6.2mg, Nobiletin 3.6mg, naringenin 3.8mg, riboflavin 4.5mg.The mixture effective ingredient is 1027.4mg.

Comparing embodiment 26

Its operational approach and equipment are basic with embodiment 1 relatively, and only different is with pretreated 100 kilograms of Fructus Aurantii Immaturuss is raw material, contains in the fluid extract of its result by raw material Fructus Aurantii Immaturus 5 grams: hesperidin 3.6mg, neohesperidin 3.9mg, Nobiletin 2.7mg, naringenin 2.8mg, Riboflavin Tetrabutyrate .7mg.The mixture effective ingredient is 626.7mg.

Comparing embodiment 26

Its operational approach and equipment are basic with embodiment one relatively, and only different is with pretreated 100 kilograms of Fructus Aurantii Immaturuss is raw material, contains in the fluid extract of its result by raw material Fructus Aurantii Immaturus 5 grams: hesperidin 4.6mg, neohesperidin 5.1mg, Nobiletin 3.1mg, naringenin 3.2mg, riboflavin 3.8mg.The mixture effective ingredient is 811.6mg.

Embodiment 27

Its operational approach and equipment are substantially with embodiment 1, only different is with 100 kilograms of pretreated Fructus Corni is raw material, contains in the fluid extract of its result by raw material Fructus Corni 5 grams: contain cornin 12.6mg, maloic acid 6.8mg, gallic acid 5.6mg, ursolic acid 6.8mg.The mixture effective ingredient is 956.9mg.

Comparing embodiment 27

Its operational approach and equipment are basic with comparing embodiment 1, only different is with pretreated 100 kilograms of Fructus Corni is raw material, contains in the fluid extract of its result by raw material Fructus Corni 5 grams: contain cornin 8.8mg, maloic acid 4.4mg, gallic acid 3.8mg, ursolic acid 4.4mg.The mixture effective ingredient is 583.7mg.

Comparing embodiment 27

Its operational approach and equipment are basic with comparing embodiment one, only different is with pretreated 100 kilograms of Fructus Corni is raw material, contains in the fluid extract of its result by raw material Fructus Corni 5 grams: contain cornin 10.2mg, maloic acid 5.4mg, gallic acid 4.5mg, ursolic acid 5.4mg.The mixture effective ingredient is 755.9mg.

Embodiment 28

Its operational approach and equipment are substantially with embodiment 1, only different is with 100 kilograms of pretreated Radix Paeoniae Rubra is raw material, contain in the fluid extract of its result by raw material Radix Paeoniae Rubra 5 grams: paeoniflorin 6.3mg, paeonol 5.9mg, the 4.5mg of paeoniflorin unit, Galla Turcica (Galla Helepensis) acyl paeoniflorin 3.6mg, Lactiflorin. 4.2mg.The mixture effective ingredient is 811.7mg.

Comparing embodiment 28

Its operational approach and equipment are basic with comparing embodiment 1, only different is with pretreated 100 kilograms of Radix Paeoniae Rubra is raw material, contain in the fluid extract of its result by raw material Radix Paeoniae Rubra 5 grams: paeoniflorin 3.7mg, paeonol 3.5mg, the 2.7mg of paeoniflorin unit, Galla Turcica (Galla Helepensis) acyl paeoniflorin 2.3mg, Lactiflorin. 2.6mg.The mixture effective ingredient is 495.1mg.

Comparing embodiment 28

Its operational approach and equipment are basic with comparing embodiment one, only different is with pretreated 100 kilograms of Radix Paeoniae Rubra is raw material, contain in the fluid extract of its result by raw material Radix Paeoniae Rubra 5 grams: paeoniflorin 5.1mg, paeonol 4.8mg, the 3.6mg of paeoniflorin unit, Galla Turcica (Galla Helepensis) acyl paeoniflorin 2.8mg, Lactiflorin. 3.8mg.The mixture effective ingredient is 641.2mg.

Embodiment 29

Its operational approach and equipment are substantially with embodiment 1, only different is with 100 kilograms of pretreated Radix Angelicae Pubescentiss is raw material, contain in the fluid extract of its result by raw material Radix Angelicae Pubescentis 5 grams: Columbianedin 6.3mg, isoimperatorin 5.8mg, bergapten 4.5mg, angelol 6.8mg, oleanolic acid 15.6mg, p-methyl phenol 6.5mg.The mixture effective ingredient is 776.6mg.

Comparing embodiment 29

Its operational approach and equipment are basic with comparing embodiment 1, only different is with pretreated 100 kilograms of Radix Angelicae Pubescentiss is raw material, contain in the fluid extract of its result by raw material Radix Angelicae Pubescentis 5 grams: Columbianedin 3.7mg, isoimperatorin 3.5mg, bergapten 2.7mg, angelol 4.1mg, oleanolic acid 9.6mg, p-methyl phenol 3.7mg.The mixture effective ingredient is 473.7mg.

Comparing embodiment 29

Its operational approach and equipment are basic with comparing embodiment one, only different is with pretreated 100 kilograms of Radix Angelicae Pubescentiss is raw material, contain in the fluid extract of its result by raw material Radix Angelicae Pubescentis 5 grams: Columbianedin 5.1mg, isoimperatorin 4.5mg, bergapten 3.6mg, angelol 5.4mg, oleanolic acid 12.5mg, p-methyl phenol 5.3mg.The mixture effective ingredient is 613.5mg.

Embodiment 30

Its operational approach and equipment are substantially with embodiment 1, only different is with 100 kilograms of pretreated Radixs Astragali is raw material, contain in the fluid extract of its result by the raw material Radix Astragali 5 grams: a large amount of polysaccharide 32.5mg, astragaloside 18.6mg, coumarin 12.3mg, cupreol 9.6mg, daucosterol 2.6mg, choline 4.3mg, betanin 6.3mg.The mixture effective ingredient is 770.2mg.

Comparing embodiment 30

Its operational approach and equipment are basic with comparing embodiment 1, only different is with pretreated 100 kilograms of Radixs Astragali is raw material, contain in the fluid extract of its result by the raw material Radix Astragali 5 grams: a large amount of polysaccharide 20.1mg, astragaloside 11.5mg, coumarin 8.1mg, cupreol 5.6mg, daucosterol 1.4mg, choline 2.6mg, betanin 3.8mg.The mixture effective ingredient is 469.7mg.

Comparing embodiment 30

Its operational approach and equipment are basic with comparing embodiment one, only different is with pretreated 100 kilograms of Radixs Astragali is raw material, contain in the fluid extract of its result by the raw material Radix Astragali 5 grams: a large amount of polysaccharide 26.3mg, astragaloside 14.7mg, coumarin 10.2mg, cupreol 7.6mg, daucosterol 2.1mg, choline 2.6mg, betanin 5.2mg.The mixture effective ingredient is 608.3mg.

Embodiment 31

By the cedar seed side of nourishing heart Semen Platycladi 25 gram, Radix Codonopsis 25 grams, the Radix Astragali 100 grams, Rhizoma Chuanxiong 100 grams, Radix Angelicae Sinensis 100 grams, Poria 200 grams, Radix Polygalae 25 grams, Pinellia leaven 100 grams, Radix Glycyrrhizae 10 grams, Cinnabaris 30 grams, Fructus Schisandrae Chinensis 25 grams are prepared burden, and carry out after the pretreatment as raw material again.

With pretreated above-mentioned batching is raw material for 100 kilograms, adds entry in raw material, and the water yield that is added is 8 times of raw material weight, and 55 ℃ of heating extraction are 7 hours under normal pressure, win time extracting solution and medicinal residues for the first time.To the first time medicinal residues under the pressure of 4.5 kg/cm, carry out the breaking cellular wall squeezing first time, win time press liquor and for the first time through the medicinal residues of squeezing, to in the medicinal residues of squeezing, adding entry for the first time, stir and make medicinal residues loose in water, the water yield that is added is 4 times of raw material weight, under normal pressure, carry out the heating extraction 6 hours second time in 65 ℃, extracting solution and medicinal residues for the second time for the second time.To the second time medicinal residues under the pressure of 2.5 kg/cm, carry out the breaking cellular wall squeezing second time, press liquor and for the second time through the medicinal residues of squeezing for the second time.To in the medicinal residues of squeezing, adding entry for the second time, stir and make medicinal residues loose in water, the water yield that is added is 3 times of raw material weight, 95 ℃ were carried out for the third time heating extraction 3 hours under normal pressure, medicinal residues are for the third time carried out breaking cellular wall squeezing for the third time under the pressure of 5.0 kg/cm, press liquor and medicinal residues for the third time for the third time through squeezing.

The extracting solution of three merging and the press liquor of three merging are filtered with the frame filter respectively.Filtered extracting solution and press liquor are placed the concentrating under reduced pressure jar respectively,, under 85 ℃ temperature, carry out concentrating under reduced pressure, make it be condensed into the fluid extract of proportion 1.35 in pressure 0.08MPa.Merge the fluid extract mix homogeneously, contain in the fluid extract of its result by raw material 5 grams: platydiol 25.9mg, Radix Codonopsis polysaccharide 68.9mg, ligustilide 18.9mg, pachymose 21.5mg, Semen Ziziphi Spinosae saponin 65.8mg, ligustrazine 25.3mg, ferulic acid 18.9mg, schisandrin B 35.2mg.The mixture effective ingredient is 491mg.

Comparing embodiment 31: with single jar of extraction of tradition

Batching with pretreated embodiment 31 is a raw material for 100 kilograms, adds entry in raw material, and the water yield that is added is 10 times of material quantity, and 100 ℃ of heating extraction are 2 hours under normal pressure, filters win time extracting solution and medicinal residues.In medicinal residues, add entry, the water yield that is added is 8 times of material quantity, 100 ℃ of heating extraction are 2 hours under normal pressure, filter extracting solution for the second time, the extracting solution that merges secondary, under 85 ℃ temperature, carrying out concentrating under reduced pressure under the pressure of pressure 0.08MPa, make its fluid extract that is condensed into proportion 1.35, contain in the fluid extract of its result by raw material 5 grams: platydiol 15.8mg, Radix Codonopsis polysaccharide 55.8mg, ligustilide 11.5mg, pachymose 13.2mg, Semen Ziziphi Spinosae saponin 40.1mg, ligustrazine 15.2mg, ferulic acid 11.5mg, schisandrin B 21.6mg.The mixture effective ingredient is 299mg.

The comparing embodiment hentriaconta-: the continuous extraction with application number 00107662.0 extracts

Batching with pretreated embodiment 31 is a raw material for 100 kilograms, adds entry in raw material, and the water yield that is added is 8 times of raw material weight, and 55 ℃ of heating extraction are 7 hours under normal pressure, obtains extracting solution and medicinal residues for the first time for the first time.Add entry to the first time in the medicinal residues, the water that is added is 4 times of raw material weight, carries out the heating extraction 6 hours second time in 65 ℃ under normal pressure, extracting solution and medicinal residues for the second time for the second time.Add entry to the second time in the medicinal residues, the water yield that is added is 3 times of raw material weight, and 95 ℃ were carried out for the third time heating extraction 3 hours under normal pressure, merged first, second and third time extracting solution, filtered.In the concentrating under reduced pressure jar in 0.08MPa, under 85 ℃ temperature, carry out concentrating under reduced pressure, make its fluid extract that is condensed into proportion 1.35, contain in the fluid extract of its result by raw material 5 grams: platydiol 20.9mg, Radix Codonopsis polysaccharide 55.1mg, ligustilide 15.1mg, pachymose 16.8mg, Semen Ziziphi Spinosae saponin 52.6mg, ligustrazine 25.3mg, ferulic acid 17.2mg, schisandrin B 28.2mg.The mixture effective ingredient is 369mg.

Embodiment 32

Its operational approach and equipment are substantially with embodiment 31, and only different is to prepare burden by invigorating the spleen and replenishing QI side's Radix Astragali 200 grams, Radix Codonopsis 60 grams, Radix Angelicae Sinensis 60 grams, Rhizoma Cimicifugae 60 grams, Radix Bupleuri 60 grams, Radix Glycyrrhizae 100 grams, the Rhizoma Atractylodis Macrocephalae 60 grams, Pericarpium Citri Reticulatae 60 grams.With pretreated above-mentioned batching is raw material for 100 kilograms, and the water yield that adds in raw material is 10 times of raw material weight, under normal pressure 35 ℃, and heating extraction 8 hours, win time extracting solution and medicinal residues for the first time.To the first time medicinal residues under the pressure of 5.0 kg/cm, carry out win time press liquor and of breaking cellular wall squeezing for the first time for the first time through the medicinal residues of squeezing.To the water yield that adds in the medicinal residues of squeezing for the first time is 8 times of raw material weight, carries out heating extraction 6 hours second time under 45 ℃ temperature, for the second time extracting solution and the second time medicinal residues.To the second time medicinal residues under the pressure of 5 kg/cm, carry out the breaking cellular wall squeezing second time, press liquor and for the second time through the medicinal residues of squeezing for the second time.To the water yield that adds in the medicinal residues of squeezing for the second time is 6 times of raw material weight, carries out for the third time heating extraction 2.5 hours in 65 ℃, extracting solution and medicinal residues for the third time for the third time.Medicinal residues are for the third time carried out breaking cellular wall squeezing for the third time under the pressure of 5 kg/cm, press liquor and medicinal residues for the third time for the third time through squeezing.

The extracting solution of three merging and the press liquor of three merging are mixed, become the fluid extract of proportion 1.15 in 0.06MPa concentrating under reduced pressure under 55 ℃ temperature, contain in the fluid extract of its result by raw material 5 grams: astragaloside 30.5mg, choline 104mg, astragalus polysaccharides 80.5mg, Radix Codonopsis Saponin 54.3mg, ligustilide 12.6mg, cyclobutenyl lactone 10.2mg, saikoside 63mg.The mixture effective ingredient is 385.9mg.

With nitrogen is atomization gas, and the pressure of atomization gas is that 0.4MPa carries out spray drying, sprays into temperature and is in 250 ℃ the hot-air body, forms medicated powder average diameter of particles 1600 μ m.

Comparing embodiment 32

Its operational approach and equipment and comparing embodiment 31 are basic identical, only different is with the batching of pretreated embodiment 32 is raw material for 100 kilograms, become the fluid extract of proportion 1.15 in 0.06MPa concentrating under reduced pressure under 55 ℃ temperature, contain in the fluid extract of its result by raw material 5 grams: astragaloside 18.5mg, choline 62.3mg, astragalus polysaccharides 48.6mg, Radix Codonopsis Saponin 35.6mg, ligustilide 7.8mg, cyclobutenyl lactone 6.5mg, saikoside 38.1mg.The mixture effective ingredient is 268.9mg.

Comparing embodiment 32: the continuous extraction with application number 00107662.0 extracts

Its operational approach is identical substantially with the comparing embodiment hentriaconta-with equipment, only different is with the batching of pretreated embodiment 32 is raw material for 100 kilograms, three amount of water and heating extraction temperature, to concentrate pressure and temperature etc. identical with embodiment 32, do not carry out the breaking cellular wall squeezing after each heating extraction, contain in the fluid extract of its result by raw material 5 grams: astragaloside 24.6mg, choline 83.2mg, astragalus polysaccharides 64.2mg, Radix Codonopsis Saponin 43.6mg, ligustilide 10.6mg, cyclobutenyl lactone 8.1mg, saikoside 50.3mg.The mixture effective ingredient is 328.7mg.

Embodiment 33

Its operational approach and equipment are substantially with embodiment 31, and only different is by storax pill for treating coronary heart disease side, and Styrax 50 grams, Borneolum Syntheticum 105 grams, Olibanum 105 grams, Radix Aristolochiae 210 grams, Lignum Santali Albi 210 grams are prepared burden.With 100 kilograms of pretreated above-mentioned batchings is raw material.

The water yield that adds in raw material is 5 times of raw material weight, heating extraction 8 hours under 90 ℃ the temperature under normal pressure, to the first time medicinal residues under 4.0 kilograms pressure, carry out the breaking cellular wall squeezing first time.To the water yield that adds in the medicinal residues of squeezing for the first time is 7 times of raw material weight, carries out the heating extraction 6 hours second time in 55 ℃.To the second time medicinal residues under the pressure of 4 kg/cm, carry out the breaking cellular wall squeezing second time.To the water yield that adds in the medicinal residues of squeezing for the second time is 4 times of raw material weight, carries out heating extraction 4 hours in 90 ℃, and medicinal residues are for the third time carried out breaking cellular wall squeezing for the third time under the pressure of 4 kg/cm.

To the extracting solution of three merging and the press liquor of three merging, filter respectively, become the fluid extract of proportion 1.25 at 60 ℃ of concentrating under reduced pressure in 0.055MPa, merge the fluid extract mix homogeneously, contain in the fluid extract of its result by raw material 5 grams: terpenoid 68.7mg, Borneolum Syntheticum 10.2mg, costic acid 9.2mg, constuslactone 12.5mg, camphene 5.3mg.The mixture effective ingredient is 1013.0mg.

To under 80 ℃ temperature, carry out drying, pulverizing through the medicinal residues of squeezing for the third time, medicinal residues dry, that pulverize are crossed 180 orders, with the medicinal residues fine powder of medicinal residues total amount 10% and the fluid extract mix homogeneously of proportion 1.25, with nitrogen is that atomization gas carries out spray drying, the pressure of spray gas is 0.7MPa, and it is the medicated powder granule that forms average diameter 1600 μ m in 140 ℃ the hot-air that the mixture of fluid extract and medicinal residues fine powder is injected to temperature.

Comparing embodiment 33: with single jar of extraction of tradition

Its operational approach and device and comparing embodiment 31 are basic identical, only different is with the batching of pretreated embodiment 33 is raw material for 100 kilograms, become 1.25 fluid extract in 0.055MPa at 60 ℃ of concentrating under reduced pressure, contain in the fluid extract of its result by raw material 5 grams: terpenoid 39.5mg, Borneolum Syntheticum 6.3mg, costic acid 6.5mg, constuslactone 7.2mg, camphene 3.6mg.The mixture effective ingredient is 630mg.

Comparing embodiment 33

Continuous extraction with application number 00107662.0 extracts.

Its operational approach is identical substantially with the comparing embodiment hentriaconta-with equipment, only different is with the batching of pretreated embodiment 33 is raw material for 100 kilograms, the temperature-time of three amount of water and three heating extraction, concentrated pressure and temperature etc. are identical with embodiment 33, do not carry out the breaking cellular wall squeezing after each heating extraction, contain in the fluid extract of its result by raw material 5 grams: terpenoid 54.2mg, Borneolum Syntheticum 8.2mg, costic acid 7.3mg, constuslactone 10mg, camphene 4.2mg.The mixture effective ingredient is 819mg.

Embodiment 34

Its operational approach and equipment are substantially with embodiment 31, and only different is to prepare burden by Rhizoma Chuanxiong 20 grams, Fructus Viticis 30 grams, Herba Schizonepetae 30 grams, Radix Saposhnikoviae 30 grams, Flos Chrysanthemi 240 grams, Rhizoma Coptidis 20 grams, Rhizoma Et Radix Notopterygii 20 grams, Radix Glycyrrhizae 20 grams, Radix Scutellariae 120 grams, Herba Menthae 20 grams, GAOMU 20 grams, the Radix Angelicae Dahuricae 80 grams, Fructus Gardeniae 30 grams, Fructus Forsythiae 30 grams, Radix Platycodonis 30 grams with rhizome of chuanxiong chrysanthemum supernatant side.With 100 kilograms of pretreated above-mentioned batchings is raw material.Contain in the fluid extract of its result by raw material 5 grams: pachymose is 23.1mg, and ergosterol is 1.1mg, paeoniflorin 34.7mg, paeoniflorin 20.3mg, paeonol 10.1mg.The mixture effective ingredient is 423.6mg.

Comparing embodiment 34

Its operational approach and device and comparing embodiment 31 are basic identical, only different is with the batching of pretreated embodiment 34 is raw material for 100 kilograms, contain in the fluid extract of its result by raw material 5 grams: pachymose is 14.1mg, ergosterol is 0.7mg, paeoniflorin 20.3mg, paeoniflorin 14.3mg, paeonol 6.2mg.The mixture effective ingredient is 254.2mg.

Comparing embodiment 34

Its operational approach and equipment are basic with comparing the embodiment hentriaconta-, only different is with the batching of pretreated embodiment 34 is raw material for 100 kilograms, contain in the fluid extract of its result by raw material 5 grams: pachymose is 18.4mg, ergosterol is 0.9mg, paeoniflorin 27.8mg, paeoniflorin 16.5mg, paeonol 8.2mg.The mixture effective ingredient is 338.8mg.

Embodiment 35

Its operational approach and equipment are substantially with embodiment 31, and only different is to prepare burden by Gallus Domesticus 640 grams, Radix Ginseng 128 grams, Concha Ostreae 48 grams, Radix Angelicae Sinensis 144 grams, Radix Rehmanniae Preparata 256 grams, Rhizoma Cyperi 128 grams, Radix Stellariae 26 grams, Rhizoma Dioscoreae 128 grams, Radix Salviae Miltiorrhizae 128 grams, Cornu Cervi Degelatinatum 48 grams, Semen Euryales 64 grams, Rhizoma Chuanxiong 64 grams, Radix Rehmanniae 256 grams, Radix Glycyrrhizae 32 grams, Radix Asparagi 144 grams, Ootheca Mantidis 48 grams, Carapax Trionycis 64 grams, Colla cornus cervi 128 grams, the Radix Paeoniae Alba 128 grams with WUJI BAIFENG side.With 100 kilograms of pretreated above-mentioned batchings is raw material, contains in the fluid extract of its result by raw material 5 grams: ginsenoside 67.2mg, oleanolic acid 31.2mg, catalpol 6.8mg, ligustilide 5.9mg, cyclobutenyl lactone 3.2mg, paeoniflorin 23.4mg.The mixture effective ingredient is 588.5mg.

Comparing embodiment 35

Its operational approach and equipment and comparing embodiment 31 are basic identical, only different is with the batching of pretreated embodiment 35 is raw material for 100 kilograms, contain in the fluid extract of its result by raw material 5 grams: ginsenoside 41.2mg, oleanolic acid 18.5mg, catalpol 4.1mg, ligustilide 3.5mg, cyclobutenyl lactone 1.9mg, paeoniflorin 14.1mg.The mixture effective ingredient is 319.5mg.

Comparing embodiment 35

Its operational approach and equipment are basic with comparing the embodiment hentriaconta-, only different is with the batching of pretreated embodiment 35 is raw material for 100 kilograms, contain in the fluid extract of its result by raw material 5 grams: ginsenoside 58.2mg, oleanolic acid 24.6mg, catalpol 5.3mg, ligustilide 4.7mg, cyclobutenyl lactone 2.5mg, paeoniflorin 18.6mg.The mixture effective ingredient is 450mg.

Embodiment 36

Its operational approach and equipment are substantially with embodiment 32, only different is to prepare burden by Radix Bupleuri 100 grams, Radix Angelicae Sinensis 100 grams, the Radix Paeoniae Alba 100 grams, the Rhizoma Atractylodis Macrocephalae 100 grams, Poria 100 grams, Radix Glycyrrhizae 80 grams, Herba Menthae 20 grams with carefree side, with 100 kilograms of pretreated above-mentioned batchings is raw material, contain in the fluid extract of its result by raw material 5 grams: saikoside 20.4mg, Quercetin 10.2mg, paeoniflorin 32.1mg, paeonol 10.5mg, gallic acid 1.4mg, Rhizoma Atractylodis oil 8.3mg.The mixture effective ingredient is 355.5mg.

Comparing embodiment 36

Its operational approach and equipment and comparing embodiment 32 are basic identical, only different is with the batching of pretreated embodiment 36 is raw material for 100 kilograms, contain in the fluid extract of its result by raw material 5 grams: saikoside 12.6mg, Quercetin 6.2mg, paeoniflorin 22.3mg, paeonol 6.3mg, gallic acid 0.8mg, Rhizoma Atractylodis oil 5.1mg.The mixture effective ingredient is 216mg.

Comparing embodiment 36

Its operational approach and equipment are basic with comparing embodiment 32, only different is with the batching of pretreated embodiment 36 is raw material for 100 kilograms, contain in the fluid extract of its result by raw material 5 grams: saikoside 16.5mg, Quercetin 8.2mg, paeoniflorin 25.6mg, paeonol 8.5mg, gallic acid 1.1mg, Rhizoma Atractylodis oil 6.5mg.The mixture effective ingredient is 277mg.

Embodiment 37

Its operational approach and equipment are substantially with embodiment 31, only different is to reach expectorant side with Succus Bambusae to prepare burden by Radix Scutellariae 200 grams, the Rhizoma Pinelliae 150 grams, Radix Et Rhizoma Rhei 200 grams, tangerine 200 grams, Radix Glycyrrhizae 100 grams, Lignum Aquilariae Resinatum 50 grams, with 100 kilograms of pretreated above-mentioned batchings is raw material, contain in the fluid extract of its result by raw material 5 grams: baicalin 45.9mg, wogonin 20.5mg, Rhizoma Pinelliae polysaccharide 64mg, chrysophanol 18.6mg, emodin 18.6mg, hesperidin 31.4mg, enoxolone 26.5mg.The mixture effective ingredient is 364.7mg.

Comparing embodiment 37

Its operational approach and equipment and comparing embodiment 31 are basic identical, only different is with the batching of pretreated embodiment 37 is raw material for 100 kilograms, contain in the fluid extract of its result by raw material 5 grams: baicalin 27.2mg, wogonin 13.2mg, Rhizoma Pinelliae polysaccharide 38.6mg, chrysophanol 11.2mg, emodin 11.2mg, hesperidin 19.2mg, enoxolone 16.2mg.The mixture effective ingredient is 218.8mg.

Comparing embodiment 37

Its operational approach and equipment are basic with comparing the embodiment hentriaconta-, only different is with the batching of pretreated embodiment 37 is raw material for 100 kilograms, contain in the fluid extract of its result by raw material 5 grams: baicalin 36.2mg, wogonin 16.5mg, Rhizoma Pinelliae polysaccharide 52.1mg, chrysophanol 14.9mg, emodin 14.9mg, hesperidin 25.1mg, enoxolone 21.1mg.The mixture effective ingredient is 291.8mg.

Embodiment 38

Its operational approach and equipment are substantially with embodiment 33, only different is by Radix Ginseng 8.2 grams with Shenrong Baifeng side, Radix Angelicae Sinensis 39 grams, the Radix Paeoniae Alba 39 grams, Semen Trigonellae 30 grams, Rhizoma Cyperi 31 grams, Radix Scutellariae 30 grams, Cornu Cervi Pantotrichum 9.4 grams, Radix Rehmanniae Preparata 77.5 grams, Rhizoma Chuanxiong 30 grams, Radix Dipsaci 30 grams, Fructus Amomi 23 grams, Herba Taxilli 21 grams, Radix Codonopsis 40 grams, the Radix Astragali 39 grams, Rhizoma Corydalis 23 grams, the Rhizoma Atractylodis Macrocephalae 30 grams, Herba Leonuri 39 grams, Radix Glycyrrhizae 30 grams are prepared burden, with 100 kilograms of pretreated above-mentioned batchings is raw material, contain in the fluid extract of its result by raw material 5 grams: ginsenoside 67.2mg, ligustilide 5.9mg, cyclobutenyl lactone 3.2mg, paeoniflorin 28.6mg, paeonol 8.1mg, pilose antler polysaccharides 35.2mg, ligustrazine 9.2mg, ferulic acid 14.6mg, Radix Codonopsis Saponin 38mg, astragalus polysaccharides 73mg, tetrahydropalmatine 52mg.The mixture effective ingredient is 837mg.

Comparing embodiment 38

Its operational approach and equipment and comparing embodiment 33 are basic identical, and only different is with the batching of pretreated embodiment 38 is raw material for 100 kilograms, contains in the fluid extract of its result by raw material 5 grams: ginsenoside 38.6mg, ligustilide 3.5mg, cyclobutenyl lactone 2.5mg, paeoniflorin 17.3mg, paeonol 4.9mg, pilose antler polysaccharides 21.6mg, ligustrazine 5.6mg, ferulic acid 8.6mg, Radix Codonopsis Saponin 23.1mg, astragalus polysaccharides 43.2mg, tetrahydropalmatine 32.1mg.The mixture effective ingredient is 502mg.

Comparing embodiment 38

Its operational approach and equipment are basic with embodiment 33 relatively, and only different is with the batching of pretreated embodiment 38 is raw material for 100 kilograms, contains in the fluid extract of its result by raw material 5 grams: ginsenoside 53.7mg, ligustilide 4.8mg, cyclobutenyl lactone 2.5mg, paeoniflorin 23.4mg, paeonol 6.5mg, pilose antler polysaccharides 24.3mg, ligustrazine 7.3mg, ferulic acid 11.7mg, Radix Codonopsis Saponin 31.4mg, astragalus polysaccharides 54.6mg, tetrahydropalmatine 42.3mg.The mixture effective ingredient is 670mg.

Embodiment 39

Its operational approach and equipment are substantially with embodiment 31, only different is to embrace dragon side by Poria 50 grams, Rhizoma Pinelliae Preparatum 31 grams, Herba Menthae 31 grams, Rhizoma Dioscoreae 25 grams, the Radix Angelicae Dahuricae 25 grams, Herba Schizonepetae 38 grams, the Radix Paeoniae Alba 25 grams, the Rhizoma Atractylodis Macrocephalae 38 grams, Cinnabaris 47 grams, Halloysitum Rubrum 25 grams, Pericarpium Citri Reticulatae 25 grams, Folium Perillae 31 grams, Concretio Silicea Bambusae 38 grams, Fructus Amomi 25 grams, Rhizoma Typhonii 31 grams, Fructus Chebulae's 25 grams, Rhizoma Chuanxiong 31 grams, Rhizoma Gastrodiae 25 grams, Herba Pogostemonis 38 grams, Cortex Magnoliae Officinalis 25 grams, Bombyx Batryticatus 25 grams, Lignum Santali Albi 25 grams, Radix Saposhnikoviae 31 grams, Radix Angelicae Pubescentis 31 grams, the grass roots of grass 25 grams, the Radix Aucklandiae 25 grams, Rhizoma Cyperi 25 grams are prepared burden, with 100 kilograms of pretreated above-mentioned batchings is raw material, contain in the fluid extract of its result by raw material 5 grams: ligustrazine 19.6mg, ferulic acid 25.8mg, chrysophanol 50.2mg, ligustilide 30mg, pachymose polysaccharide 120mg, ergosterol 15.2mg, choline 31.2mg, pinellin 22mg, menthone 4.9mg, dioscin 53.4mg, paeoniflorin 38.2mg, atractylodes lactone 38.4mg, magnolol 40.2mg.The mixture effective ingredient is 686.1mg.

Comparing embodiment 39

Its operational approach and equipment and comparing embodiment 31 are basic identical, and only different is with the batching of pretreated embodiment 39 is raw material for 100 kilograms, contains in the fluid extract of its result by raw material 5 grams: ligustrazine 11.4mg, ferulic acid 15.3mg, chrysophanol 30.2mg, ligustilide 18mg, pachymose polysaccharide 72mg, ergosterol 9.3mg, choline 18.2mg, pinellin 13.2mg, menthone 2.8mg, dioscin 33.6mg, paeoniflorin 23.4mg, atractylodes lactone 22.1mg, magnolol 24.2mg.The mixture effective ingredient is 385.2mg.

Comparing embodiment 39

Its operational approach is identical substantially with the comparing embodiment hentriaconta-with equipment, only different is with the batching of pretreated embodiment 39 is raw material for 100 kilograms, contain in the fluid extract of its result by raw material 5 grams: ligustrazine 15.6mg, ferulic acid 20.2mg, chrysophanol 40.6mg, ligustilide 24mg, pachymose polysaccharide 96mg, ergosterol 12.2mg, choline 24.3mg, pinellin 17.6mg, menthone 4.1mg, dioscin 42.3mg, paeoniflorin 30.2mg, atractylodes lactone 30.6mg, magnolol 32.1mg.The mixture effective ingredient is 483.2mg.

Embodiment 40

Its operational approach and equipment are substantially with embodiment 31, only different is with protect and the side by crataegus pin natifida var. Major 5.6 grams, Massa Medicata Fermentata preparata 5.6 grams, Poria 2.1 grams, the Rhizoma Pinelliae 2.1 grams, Pericarpium Citri Reticulatae 2.1 grams, fry Semen Raphani 2.1 grams, Fructus Forsythiae 2.1 grams are prepared burden, with 100 kilograms of pretreated above-mentioned batchings is raw material, contain in the fluid extract of its result by raw material 5 grams: linoleic acid 12.4mg, chlorogenic acid 32.1mg, Quercetin 8.2mg, rutin 5.2mg, su-fuling is 0.34mg, hesperidin 47.2mg, forsythin 3.4mg.The mixture effective ingredient is 435.4mg.

Comparing embodiment 40

Its operational approach and equipment and comparing embodiment 31 are basic identical, only different is with the batching of pretreated embodiment 40 is raw material for 100 kilograms, contain in the fluid extract of its result by raw material 5 grams: linoleic acid 7.29mg, chlorogenic acid 19.2mg, Quercetin 4.9mg, rutin 3.2mg, su-fuling are 0.21mg, hesperidin 29.2mg, forsythin 2.04mg.The mixture effective ingredient is 243.5mg.

Comparing embodiment 40

Its operational approach is identical substantially with the comparing embodiment hentriaconta-with equipment, only different is with the batching of pretreated embodiment 40 is raw material for 100 kilograms, contain in the fluid extract of its result by raw material 5 grams: linoleic acid 8.94mg, chlorogenic acid 22.1mg, Quercetin 5.9mg, rutin 4.3mg, su-fuling are 0.26mg, hesperidin 38.2mg, forsythin 2.9mg.The mixture effective ingredient is 305.9mg.

Embodiment 41

Its operational approach and equipment are substantially with embodiment 32, only different is with body-building consolidating superficial resistance side, preparing burden by the Radix Astragali 40 grams, the Rhizoma Atractylodis Macrocephalae 20 grams, Radix Saposhnikoviae 20 grams, Bulbus Lilii 40 grams, Radix Platycodonis 30 grams, is raw material with 100 kilograms of pretreated above-mentioned batchings, contains in the fluid extract of its result by raw material 5 grams: astragaloside 26.8mg, Rhzoma Atractylodis Lanceae volatile oil 15.3mg, atractylodes lactone 11.5mg, octanal 9.6mg, β-heerabolene 7.1mg, aldehyde C-9 9.3mg, kikyosaponin 15.6mg.The mixture effective ingredient is 335.8mg.

Comparing embodiment 41

Its operational approach and equipment and comparing embodiment 32 are basic identical, only different is with the batching of pretreated embodiment 41 is raw material for 100 kilograms, contain in the fluid extract of its result by raw material 5 grams: astragaloside 16.1mg, Rhzoma Atractylodis Lanceae volatile oil 9.5mg, atractylodes lactone 6.8mg, octanal 5.9mg, β-heerabolene 4.6mg, aldehyde C-9 5.6mg, kikyosaponin 9.4mg.The mixture effective ingredient is 191.8mg.

Comparing embodiment 41

Its operational approach and equipment and comparing embodiment dotriacontyl are originally identical, only different is with the batching of pretreated embodiment 41 is raw material for 100 kilograms, contain in the fluid extract of its result by raw material 5 grams: astragaloside 21.3mg, Rhzoma Atractylodis Lanceae volatile oil 12.4mg, atractylodes lactone 9.2mg, octanal 8.8mg, β-heerabolene 5.7mg, aldehyde C-9 6.5mg, kikyosaponin 12.3mg.The mixture effective ingredient is 235.9mg.

Embodiment 42

Its operational approach and equipment are substantially with embodiment 32, only different is with child lung heat clearing side, by Herba Ephedrae 10 grams, Semen Armeniacae Amarum 20 grams, Gypsum Fibrosum 40 grams, Radix Glycyrrhizae 10 grams, Cortex Mori 30 grams, cortex trichosanthis 30 grams, Radix Scutellariae 40 grams, Radix Isatidis 40 grams, tangerine 30 grams, Rhizoma Pinelliae Preparatum 30 grams, Fructus Perillae 20 grams, Semen Lepidii (Semen Descurainiae) 10 grams, Bulbus Fritillariae Thunbergii 40 grams, Folium Perillae 20 grams, Herba Asari 8 grams, Herba Menthae 30 grams, Folium Eriobotryae 40 grams, Rhizoma Cynanchi Stauntonii 30 grams, Radix Peucedani 20 grams, Rhizoma Acori Graminei 30 grams, Radix Trichosanthis 30 grams, blue or green Meng not 10 grams prepares burden, with 100 kilograms of pretreated above-mentioned batchings is raw material, contain in the fluid extract of its result by raw material 5 grams: amygdalin 5.2mg, baicalin 22.9mg, ephedrine 7.7mg, peimine 2.12mg.The mixture effective ingredient is 252.3mg.

Comparing embodiment 42

Its operational approach and equipment and comparing embodiment 32 are basic identical, only different is with the batching of pretreated embodiment 42 is raw material for 100 kilograms, contains in the fluid extract of its result by raw material 5 grams: amygdalin 3.2mg, baicalin 13.7mg, ephedrine 4.6mg, peimine 1.3mg.The mixture effective ingredient is 164.5mg.

Comparing embodiment 42

Its operational approach and equipment and comparing embodiment dotriacontyl are originally identical, only different is with the batching of pretreated embodiment 42 is raw material for 100 kilograms, contain in the fluid extract of its result by raw material 5 grams: amygdalin 4.12mg, baicalin 18.4mg, ephedrine 6.2mg, peimine 1.7mg.The mixture effective ingredient is 216.3mg.

Embodiment 43

Its operational approach and equipment are substantially with embodiment 31, only different is with Mingmu-Dihuang side, prepare burden by Radix Rehmanniae Preparata 160 grams, Fructus Corni 80 grams, Cortex Moutan 60 grams, Rhizoma Dioscoreae 80 grams, Poria 60 grams, Rhizoma Alismatis 60 grams, Fructus Lycii 60 grams, Flos Chrysanthemi 60 grams, Radix Angelicae Sinensis 60 grams, the Radix Paeoniae Alba 60 grams, Fructus Tribuli 60 grams, Concha Haliotidis 80 grams, with 10 kilograms of pretreated above-mentioned batchings is raw material, contain in the fluid extract of its result by raw material 5 grams: catalpol 12.5mg, cornin 70.1mg, alisol 20.4mg, paeoniflorin 72mg, dioscin 6.9mg.The mixture effective ingredient is 661.3mg.

Comparing embodiment 43

Its operational approach and equipment and comparing embodiment 31 are basic identical, only different is with the batching of pretreated embodiment 42 is raw material for 100 kilograms, contain in the fluid extract of its result by raw material 5 grams: catalpol 7.5mg, cornin 42.6mg, alisol 12.5mg, paeoniflorin 44.2mg, dioscin 4.4mg.The mixture effective ingredient is 401.6mg.

Comparing embodiment 43

Its operational approach is identical substantially with the comparing embodiment hentriaconta-with equipment, only different is with the batching of pretreated embodiment 43 is raw material for 100 kilograms, contain in the fluid extract of its result by raw material 5 grams: catalpol 10mg, cornin 56mg, alisol 16.2mg, paeoniflorin 57.3mg, dioscin 5.5mg.The mixture effective ingredient is 486.0mg.

Embodiment 44

By protecting first soup, Cortex Cinnamomi 2.1 grams, Radix Glycyrrhizae 2.1 grams, Radix Ginseng 5.6 grams, the Radix Astragali 5.6 grams are prepared burden, and carry out pretreatment again as raw material.

With 100 kilograms of pretreated above-mentioned batchings is raw material, in raw material, add entry, the water yield that is added is 10 times of raw material weight, 65 ℃ of heating extraction of normal pressure 8 hours, win time extracting solution and medicinal residues for the first time, to the first time medicinal residues under the pressure of 4 kg/cm, carry out the breaking cellular wall squeezing first time, win time press liquor and for the first time through the medicinal residues of squeezing, to in the medicinal residues of squeezing, adding entry for the first time, stir and make medicinal residues loose in water, the water yield that is added is 7 times of raw material weight, carries out the heating extraction 6 hours second time in 55 ℃ under normal pressure, extracting solution and medicinal residues for the second time for the second time.To the second time medicinal residues under the pressure of 5 kg/cm, carry out the breaking cellular wall squeezing second time, press liquor and for the second time through the medicinal residues of squeezing for the second time.To in the medicinal residues of squeezing, adding entry for the second time, stir and make medicinal residues loose in water, the water yield that is added is 4 times of raw material weight, 45 ℃ were carried out for the third time heating extraction 4 hours under normal pressure, medicinal residues are for the third time carried out breaking cellular wall squeezing for the third time under the pressure of 4.5 kg/cm, press liquor and medicinal residues for the third time for the third time through squeezing.

The extracting solution of three merging and the press liquor of three merging are filtered with the frame filter respectively.Filtered extracting solution and press liquor are placed the concentrating under reduced pressure jar respectively, in pressure 0.06MPa, under 70 ℃ temperature, carry out concentrating under reduced pressure, make it be condensed into the fluid extract of proportion 1.15, merge fluid extract, contain in the fluid extract of its result by raw material 5 grams: glycyrrhizin 57.5mg, liquiritin 56mg, isoliquiritin 17mg, neoliquriitin 1.1mg, Radix Ginseng general glycoside 105.2mg, astragaloside 4.71mg, Radix Astragali second glycoside 2.95mg and eugenol 0.81mg.The mixture effective ingredient is 491mg.

Comparing embodiment 44: with single jar of extraction of tradition

Batching with pretreated embodiment 44 is a raw material for 100 kilograms, adds entry in raw material, and the water yield that is added is 10 times of material quantity, and 100 ℃ of heating extraction are 2 hours under normal pressure, filters win time extracting solution and medicinal residues.In medicinal residues, add entry, the water yield that is added is 8 times of material quantity, 100 ℃ of heating extraction are 2 hours under normal pressure, filter extracting solution for the second time, the extracting solution that merges secondary, under 70 ℃ temperature, carrying out concentrating under reduced pressure under the pressure of pressure 0.06MPa, make its fluid extract that is condensed into proportion 1.15, merge fluid extract, contain in the fluid extract of its result by raw material 5 grams: glycyrrhizin 34.5mg, liquiritin 33.6mg, isoliquiritin 10.2mg, neoliquriitin 0.66mg, Radix Ginseng general glycoside 63.2mg, astragaloside 2.8mg, Radix Astragali second glycoside 1.89mg and eugenol 0.49mg.The mixture effective ingredient is 299mg.

Comparing embodiment 44: the continuous extraction with application number 00107662.0 extracts

Batching with pretreated embodiment 44 is a raw material for 100 kilograms, adds entry in raw material, and the water yield that is added is 10 times of raw material weight, 65 ℃ of heating extraction of normal pressure 8 hours, and win time extracting solution and medicinal residues for the first time.Add entry to the first time in the medicinal residues, the water that is added is 7 times of raw material weight, under normal pressure, carry out the heating extraction 6 hours second time in 55 ℃, get extracting solution and medicinal residues for the second time for the second time, add entry to the second time in the medicinal residues, the water yield that is added is 4 times of raw material weight, and 45 ℃ were carried out for the third time heating extraction 4 hours under normal pressure.Merge first, second and third time extracting solution, filter, under the pressure of pressure 0.06MPa, carry out concentrating under reduced pressure under 70 ℃ the temperature, make its fluid extract that is condensed into proportion 1.15, merge fluid extract, contain glycyrrhizin 46.5mg in the fluid extract of its result by raw material 5 grams, liquiritin 44mg, isoliquiritin 13.6mg, neoliquriitin 0.87mg, Radix Ginseng general glycoside 84.2mg, astragaloside 3.7mg, Radix Astragali second glycoside 2.35mg and eugenol 0.65mg.The mixture effective ingredient is 369mg.

Embodiment 45

Its operational approach and equipment are substantially with embodiment 44, and only different is by the Poria glycyrrhiza decoction, and the Rhizoma Pinelliae 3.2 grams, Poria 3.2 grams, Rhizoma Zingiberis Recens 3.2 grams, Ramulus Cinnamomi 2.1 grams, Radix Glycyrrhizae 2.1 grams are prepared burden, and are raw material with 100 kilograms of pretreated above-mentioned batchings.

In raw material, add the water yield and be 4 times of raw material weight, 30 ℃ of heating extraction of normal pressure 4 hours, win time extracting solution and medicinal residues for the first time.To the first time medicinal residues under the pressure of 1.5 kg/cm, carry out win time press liquor and of breaking cellular wall squeezing for the first time for the first time through the medicinal residues of squeezing.To the water yield that adds in the medicinal residues of squeezing for the first time is 3 times of material quantity, carries out heating extraction 6 hours second time under 65 ℃ temperature, for the second time extracting solution and the second time medicinal residues.To the second time medicinal residues under the pressure of 1 kg/cm, carry out second an ancient unit of weight equal to 20 or 24 *taels of silver breaking cellular wall squeezing, press liquor and for the second time through the medicinal residues of squeezing for the second time.To the water yield that adds in the medicinal residues of squeezing for the second time is 4 times of raw material weight, carries out for the third time heating extraction 4 hours under 90 ℃ temperature, extracting solution and medicinal residues for the third time for the third time.Medicinal residues are for the third time squeezed under the pressure of 4.5 kg/cm for the third time, press liquor and medicinal residues for the third time for the third time through squeezing.

The extracting solution of three merging and the press liquor of three merging are mixed the fluid extract that becomes proportion 1.21 under the pressure of 0.07MPa in 75 ℃ of concentrating under reduced pressure, contain in the fluid extract of its result by raw material 5 grams: su-fuling is 1.7mg, ergosterol is 0.1mg, glycyrrhizin 57.1mg, liquiritin 56mg, isoliquiritin 17mg.The mixture effective ingredient is 263.8mg.

Comparing embodiment 45:

Its operational approach and equipment and comparing embodiment 44 are basic identical, only different is with the batching of pretreated embodiment 45 is raw material for 100 kilograms, under the pressure of 0.07MPa, become the fluid extract of proportion 1.21 in 75 ℃ of concentrating under reduced pressure, contain in the fluid extract of its result by raw material 5 grams: su-fuling is 1.02mg, ergosterol is 0.06mg, glycyrrhizin 34.9mg, liquiritin 36.6mg, isoliquiritin 10.6mg.The mixture effective ingredient is 163.5mg.

Comparing embodiment 45: the continuous extraction with application number 00107662.0 extracts

Its operational approach and equipment and comparing embodiment four pentadecyls are originally identical, only different is with the batching of embodiment after the pretreatment 45 is raw material for 100 kilograms, the temperature of three amount of water and heating extraction, time, concentrate pressure and temperature and embodiment 45 identical, do not carry out the breaking cellular wall squeezing after each heating extraction, contain in the fluid extract of its result by raw material 5 grams: su-fuling is 1.37mg, and ergosterol is 0.08mg, glycyrrhizin 45.6mg, liquiritin 44.2mg, isoliquiritin 17.1mg.The mixture effective ingredient is 190.0mg.

Embodiment 46

Its operational approach and equipment are substantially with embodiment 44, only different is by Decoction of Notopterygium for Rheumatism, Rhizoma Et Radix Notopterygii 3.2 grams, Radix Angelicae Pubescentis 2.1 grams, Rhizoma Chuanxiong 2.1 grams, Radix Glycyrrhizae Preparata 2.1 grams, Rhizoma Ligustici 2.1 grams, Radix Saposhnikoviae 2.1 grams, Fructus Viticis 2.1 grams are prepared burden, and are raw material with 100 kilograms of pretreated above-mentioned batchings.

Add the water yield and be 10 times of raw material weight in raw material, heating extraction is 8 hours under the temperature of 90 ℃ of normal pressures.To the first time medicinal residues be 8 times of raw material weight in carrying out breaking cellular wall squeezing for the first time under the pressure of 5.0 kg/cm to the water yield that in the medicinal residues of squeezing, adds for the first time, under 95 ℃ temperature, carry out the heating extraction 6 hours second time.To the second time medicinal residues under the pressure of 5 kg/cm, carry out the breaking cellular wall squeezing second time.To the water yield that adds in the medicinal residues of squeezing for the second time is that 6 times of raw material weight carried out heating extraction 4 hours to 100 ℃.Medicinal residues are for the third time carried out breaking cellular wall squeezing for the third time under the pressure of 5 kg/cm.

To the extracting solution of three merging and the press liquor of three merging, become the fluid extract of proportion 1.20 at 70 ℃ of concentrating under reduced pressure respectively at 0.065MPa, merge the fluid extract mix homogeneously, contain in the fluid extract of its result by raw material 5 grams: angelol 87.3mg, angelicin 214.2mg, ligustilide 26.1mg, cnidium lactone 23.95mg, chuanxingol 16.25mg, ferulic acid 22.5mg, liquiritin 56mg.The mixture effective ingredient is 1013.0mg.

To under 100 ℃ temperature, carry out drying and crushing through the medicinal residues of squeezing for the third time, the medicinal residues of drying and crushing will be crossed 100 orders.With 15% the medicinal residues fine powder of medicinal residues gross weight and the fluid extract mix homogeneously of proportion 1.20, with the compressed air is that atomization gas carries out spray drying, the pressure of spray gas is 0.9MPa, it is in 200 ℃ the hot-air that the mixture of fluid extract and medicinal residues fine powder is injected to temperature, forms the granule of average diameter 1000 μ m.

Comparing embodiment 46:

Its operational approach and device and comparing embodiment 44 are basic identical, only different is with the batching of pretreated embodiment 46 is raw material for 100 kilograms, under the pressure of 0.065MPa, become the fluid extract of proportion 1.20 in 70 ℃ of concentrating under reduced pressure, contain in the fluid extract of its result by raw material 5 grams: angelol 52.3mg, angelicin 124.2mg, ligustilide 15.1mg, cnidium lactone 15.05mg, chuanxingol 10.5mg, ferulic acid 13.5mg, liquiritin 34.5mg.The mixture effective ingredient is 630mg.

Comparing embodiment 46: the continuous extraction with application number 00107662.0 extracts

Its operational approach and equipment and comparing embodiment four tetradecyls are originally identical, only different is with the batching of pretreated embodiment 46 is raw material for 100 kilograms, three amount of water, the temperature of three heating extraction, time, concentrated pressure and temperatures etc. are identical with embodiment 46, do not carry out the breaking cellular wall squeezing after each heating extraction, contain in the fluid extract of its result by raw material 5 grams: angelol 69.73mg, angelicin 165.2mg, ligustilide 20.6mg, cnidium lactone 19.05mg, chuanxingol 12.55mg, ferulic acid 17.6mg, liquiritin 44.2mg.The mixture effective ingredient is 819mg.

Embodiment 47

Its operational approach and equipment are substantially with embodiment 44, and only different is to press Yougui to admire, and prepare burden by Radix Rehmanniae Preparata 5.6 grams, Rhizoma Dioscoreae 3.0 grams, mountain Zhu 3.0 grams, Cortex Cinnamomi 2.1 grams, Radix Aconiti Lateralis Preparata 1.5 grams, Fructus Lycii 3.0 grams, Radix Glycyrrhizae Preparata 2.1 grams, the Cortex Eucommiae 3.0 grams.With 100 kilograms of pretreated above-mentioned batchings is raw material, contains in the fluid extract of its result by raw material 5 grams: dioscin 4.81mg, choline 58.1mg, allantoin 1.91mg, eugenol 0.60mg, aconitine 17.5mg, carotene 30.15mg, liquiritin 56.1mg.The mixture effective ingredient is 338.4mg.

Comparing embodiment 47

Its operational approach and equipment are fully with comparing embodiment 44, only different is with the batching of pretreated the foregoing description 47 is raw material for 100 kilograms, contain in the fluid extract of its result by raw material 5 grams: dioscin 2.81mg, choline 34.8mg, allantoin 1.2mg, eugenol 0.36mg, aconitine 13.5mg, carotene 16.75mg, liquiritin 36.6mg.The mixture effective ingredient is 205mg.

Comparing embodiment 47

Its operational approach and equipment and comparing embodiment four tetradecyls are originally identical, only different is with the batching of pretreated embodiment 47 is raw material for 100 kilograms, contain in the fluid extract of its result by raw material 5 grams: dioscin 3.84mg, choline 46.01mg, allantoin 1.53mg, eugenol 0.48mg, aconitine 15.5mg, carotene 24.9mg, liquiritin 44.8mg.The mixture effective ingredient is 243mg.

Embodiment 48

Its operational approach and equipment are substantially with embodiment 45, only different is by Sinensis Decoction, Semen Phaseoli 3.2 grams, Radix Angelicae Sinensis 3.2 grams are prepared burden, and are raw material with 100 kilograms of pretreated above-mentioned batchings, contain in the fluid extract of its result by raw material 5 grams: ligustilide 2.3mg, Radix Angelicae Sinensis arone 0.54mg, paeoniflorin 34.1mg, paeoniflorin 20.7mg, paeonol 10.1mg, baicalin 24.9mg, baicalin 5.3mg.The mixture effective ingredient is 196.0mg.

Comparing embodiment 48

Its operational approach and equipment are basic with comparing embodiment 45, only different is with the batching of pretreated embodiment 48 is raw material for 100 kilograms, contain in the fluid extract of its result by raw material 5 grams: ligustilide 1.39mg, Radix Angelicae Sinensis arone 0.34mg, paeoniflorin 23.2mg, paeoniflorin 13.5mg, paeonol 6.09mg, baicalin 14.8mg, baicalin 3.13mg.The mixture effective ingredient is 129.0mg.

Comparing embodiment 48

Its operational approach and equipment are basic with comparing embodiment 45, only different is with the batching of pretreated embodiment 48 is raw material for 100 kilograms, contain in the fluid extract of its result by raw material 5 grams: ligustilide 1.83mg, Radix Angelicae Sinensis arone 0.43mg, paeoniflorin 27.3mg, paeoniflorin 16.8mg, paeonol 8.18mg, baicalin 19mg, baicalin 4.2mg.The mixture effective ingredient is 162.0mg.

Embodiment 49

Its operational approach and equipment are substantially with embodiment 44, and only different is by Zhen Wu Tang, Decoction for strengthening the Spleen-Yang, and Poria 3.2 grams, Radix Paeoniae 3.2 grams, Rhizoma Zingiberis Recens 3.2 grams, the Rhizoma Atractylodis Macrocephalae 4.5 grams, gun additioner 2.1 grams are prepared burden, and are raw material with 100 kilograms of pretreated above-mentioned batchings.Contain in the fluid extract of its result by raw material 5 grams: pachymose 231.1mg, ergosterol 0.1mg, paeoniflorin 34.7mg, paeoniflorin 20.3mg, paeonol 10.1mg, oxypaeoniflorin 0.63mg, aconitine 17.9mg.The mixture effective ingredient is 478.9mg.

Comparing embodiment 49

Its operational approach and equipment are basic with comparing embodiment 44, only different is with the batching of pretreated embodiment 49 is raw material for 100 kilograms, contain in the fluid extract of its result by raw material 5 grams: pachymose 135.5mg, ergosterol 0.06mg, paeoniflorin 20.7mg, paeoniflorin 12.4mg, paeonol 6.09mg, oxypaeoniflorin 0.37mg, aconitine 10.8mg.The mixture effective ingredient is 270.7mg.

Comparing embodiment 49

Its operational approach and equipment are basic with comparing embodiment 44, only different is with the batching of pretreated embodiment 49 is raw material for 100 kilograms, contain in the fluid extract of its result by raw material 5 grams: pachymose 185.1mg, ergosterol 0.08mg, paeoniflorin 29.8mg, paeoniflorin 17.0mg, paeonol 8.1mg, oxypaeoniflorin 0.50mg, aconitine 13.7mg.The mixture effective ingredient is 386.9mg.

Embodiment 50

Its operational approach and equipment are substantially with embodiment 46, and only different is by four refreshing soup, and Fructus Psoraleae 3.2 grams, Fructus Evodiae 3.2 grams, nutmeg 2.1 grams, the five tastes 2.1 grams are prepared burden, and are raw material with 100 kilograms of pretreated above-mentioned batchings.Contain in the fluid extract of its result by raw material 5 grams: psoralen 472.3mg, isobavachin 26.1mg, Coryfolin 51.2mg, Corylifolinin 62.3mg, deoxyschizandrin 88.1mg.The mixture effective ingredient is 1400mg.

Comparing embodiment 50

Its operational approach and equipment are basic with comparing embodiment 46, only different is with the batching of pretreated embodiment 50 is raw material for 100 kilograms, contain in the fluid extract of its result by raw material 5 grams: psoralen 247.2mg, isobavachin 16.0mg, Coryfolin 33.2mg, Corylifolinin 42.3mg, deoxyschizandrin 52.9mg.The mixture effective ingredient is 832mg.

Comparing embodiment 50

Its operational approach and equipment are basic with comparing embodiment 46, only different is with the batching of pretreated embodiment 50 is raw material for 100 kilograms, contain in the fluid extract of its result by raw material 5 grams: psoralen 317.1mg, isobavachin 19.5mg, Coryfolin 38.6mg, Corylifolinin 46.9mg, deoxyschizandrin 69.9mg.The mixture effective ingredient is 1026mg.

Embodiment 51

Its operational approach and equipment are substantially with embodiment 44, only different is by Fructus Evodiae decoction, Fructus Evodiae 3.2 grams, Radix Ginseng 3.2 grams, Fructus Jujubae 2.1 grams, Rhizoma Zingiberis Recens 3.2 grams are prepared burden, with 100 kilograms of pretreated above-mentioned batchings is raw material, contains in the fluid extract of its result by raw material 5 grams: cornin 3.6mg, Radix Ginseng general glycoside 10.8mg, Radix Ginseng total sugar 172.5mg, rutin 16.9mg, VC 3.7mg, shogaol 1.85mg.The mixture effective ingredient is 415.2mg.

Comparing embodiment 51

Its operational approach and equipment are basic with comparing embodiment 44, only different is with the batching of pretreated embodiment 51 is raw material for 100 kilograms, contain in the fluid extract of its result by raw material 5 grams: cornin 2.1mg, Radix Ginseng general glycoside 7.1mg, Radix Ginseng total sugar 100.3mg, rutin 9.9mg, VC 2.1mg, shogaol 1.02mg.The mixture effective ingredient is 245.9mg.

Comparing embodiment 51

Its operational approach and equipment are basic with comparing embodiment 44, only different is with the batching of pretreated embodiment 51 is raw material for 100 kilograms, contain in the fluid extract of its result by raw material 5 grams: cornin 2.6mg, Radix Ginseng general glycoside 8.1mg, Radix Ginseng total sugar 125.5mg, rutin 11.7mg, VC2.7mg, shogaol 1.53mg.The mixture effective ingredient is 312.8mg.

Embodiment 52

Its operational approach and equipment are substantially with embodiment 46, only different is by giving birth to arteries and veins soup, Radix Ophiopogonis 3.2, gram, Fructus Schisandrae Chinensis 3.2 grams, Radix Ginseng 3.2 grams were prepared burden, with 100 kilograms of pretreated above-mentioned batchings is raw material, contain in the fluid extract of its result by raw material 5 grams: Camphora 21.1mg, deoxyschizandrin 393.3mg, schisandrin B 69.7mg, Radix Ginseng general glycoside 386.9mg.The mixture effective ingredient is 1742mg.

Comparing embodiment 52

Its operational approach and equipment are basic with comparing embodiment 46, only different is with the batching of pretreated embodiment 52 is raw material for 100 kilograms, contain in the fluid extract of its result by raw material 5 grams: Camphora 13.2mg, deoxyschizandrin 213.9mg, schisandrin B 42.0mg, Radix Ginseng general glycoside 239.4mg.The mixture effective ingredient is 1125mg.

Comparing embodiment 52

Its operational approach and equipment are basic with comparing embodiment 46, only different is with the batching of pretreated embodiment 52 is raw material for 100 kilograms, contain in the fluid extract of its result by raw material 5 grams: Camphora 15.8mg, deoxyschizandrin 300.1mg, schisandrin B 56.2mg, Radix Ginseng general glycoside 284.1mg.The mixture effective ingredient is 1442mg.

Embodiment 53

Its operational approach and equipment are substantially with embodiment 46, only different is by flat stomach soup, Rhizoma Atractylodis 3.2 grams, Pericarpium Citri Reticulatae 3.2 grams, Radix Glycyrrhizae Preparata 2.1 grams, Sichuan Cortex Magnoliae Officinalis (processed with Rhizoma Zingiberis Recens) 2.1 grams are prepared burden, and are raw material with 100 kilograms of pretreated above-mentioned batchings, contain in the fluid extract of its result by raw material 5 grams: atractylol 172.1mg, hinesol 37.3mg, atractylone 12.6mg, magnolol 0.17mg, hesperidin 265.1mg, liquiritin 56.7mg, isoliquiritin 17.2mg.The mixture effective ingredient is 1122.3mg.

Comparing embodiment 53

Its operational approach and equipment are basic with comparing embodiment 46, only different is with the batching of pretreated embodiment 53 is raw material for 100 kilograms, contain in the fluid extract of its result by raw material 5 grams: atractylol 102.2mg, hinesol 21.2mg, atractylone 7.16mg, magnolol 0.101mg, hesperidin 160.5mg, liquiritin 34.67mg, isoliquiritin 10.2mg.The mixture effective ingredient is 622.5mg.

Comparing embodiment 53

Its operational approach and equipment are basic with comparing embodiment 46, only different is with the batching of pretreated embodiment 53 is raw material for 100 kilograms, contain in the fluid extract of its result by raw material 5 grams: atractylol 123.5mg, hinesol 30.1mg, atractylone 8.86mg, magnolol 0.15mg, hesperidin 205.1mg, liquiritin 44.6mg, isoliquiritin 14.7mg.The mixture effective ingredient is 782.0mg.

Embodiment 54

Its operational approach and equipment are substantially with embodiment 45, only different is cooks ground 50 grams, Radix Angelicae Sinensis (parched with wine) 25 grams, Rhizoma Chuanxiong 15 grams, the Radix Paeoniae Alba 15 grams by SIWU TANG wine and prepares burden, with 100 kilograms of pretreated above-mentioned batchings is raw material, contain in the fluid extract of its result by raw material 5 grams: ligustilide 2.3mg, Radix Angelicae Sinensis arone 0.56mg, cnidium lactone 23.9mg, ferulic acid 22.5mg, paeoniflorin 34.8mg, paeoniflorin 20.3mg.The mixture effective ingredient is 208.1mg.

Comparing embodiment 54

Its operational approach and equipment are basic with comparing embodiment 45, only different is with the batching of pretreated embodiment 54 is raw material for 100 kilograms, contain in the fluid extract of its result by raw material 5 grams: ligustilide 1.38mg, Radix Angelicae Sinensis arone 0.36mg, cnidium lactone 14.9mg, ferulic acid 14.5mg, paeoniflorin 20.5mg, paeoniflorin 12.5mg.The mixture effective ingredient is 124.1mg.

Comparing embodiment 54

Its operational approach and equipment are basic with comparing embodiment 45, only different is with the batching of pretreated embodiment 54 is raw material for 100 kilograms, contain in the fluid extract of its result by raw material 5 grams: ligustilide 1.6mg, Radix Angelicae Sinensis arone 0.46mg, cnidium lactone 18.0mg, ferulic acid 18.5mg, paeoniflorin 27.5mg, paeoniflorin 16.2mg.The mixture effective ingredient is 173.1mg.

Embodiment 55

Its operational approach and equipment are substantially with embodiment 44, only different is by decoction of ten powerful tonics, Radix Ginseng 3.2 grams, Cortex Cinnamomi 2.1 grams, Rhizoma Chuanxiong 2.1 grams, Radix Rehmanniae Preparata 2.1 grams, Poria 2.1 grams, the Rhizoma Atractylodis Macrocephalae 2.1 grams, Radix Glycyrrhizae Preparata 2.1 grams, the Radix Astragali 3.2 grams, Radix Angelicae Sinensis 3.2 grams, the Radix Paeoniae Alba 2.1 grams are prepared burden, with 100 kilograms of pretreated above-mentioned batchings is raw material, contain in the fluid extract of its result by raw material 5 grams: Radix Ginseng general glycoside 42.0mg, cnidium lactone 23.9mg, ferulic acid 22.5mg, su-fuling 1.7mg, liquiritin 56mg, isoliquiritin 17mg, astragaloside 4.7mg.The mixture effective ingredient is 335.8mg.

Comparing embodiment 55

Its operational approach and equipment are basic with comparing embodiment 44, only different is with the batching of pretreated embodiment 55 is raw material for 100 kilograms, contain in the fluid extract of its result by raw material 5 grams: Radix Ginseng general glycoside 25.0mg, cnidium lactone 13.9mg, ferulic acid 13.5mg, su-fuling 1.07mg, liquiritin 33.6mg, isoliquiritin 10.5mg, astragaloside 3.4mg.The mixture effective ingredient is 191.8mg.

Comparing embodiment 55

Its operational approach and equipment are basic with comparing embodiment 44, only different is with the batching of pretreated embodiment 55 is raw material for 100 kilograms, contain in the fluid extract of its result by raw material 5 grams: Radix Ginseng general glycoside 33.2mg, cnidium lactone 19.1mg, ferulic acid 17.5mg, su-fuling 1.29mg, liquiritin 56mg, isoliquiritin 13.6mg, astragaloside 3.7mg.The mixture effective ingredient is 235.9mg.

Embodiment 56

Its operational approach and equipment are substantially with embodiment 45, only different is by decoction of Eight Ingredients, Radix Angelicae Sinensis 3.2 grams, the Radix Paeoniae Alba 2.1 grams, Radix Rehmanniae Preparata 3.2 grams, Rhizoma Chuanxiong 2.1 grams, the Radix Astragali 3.2 grams, Radix Glycyrrhizae 2.1 grams, Poria 2.1 grams, the Rhizoma Atractylodis Macrocephalae 2.1 grams are prepared burden, with 100 kilograms of pretreated above-mentioned batchings is raw material, contain in the fluid extract of its result by raw material 5 grams: Radix Ginseng general glycoside 35.7mg, cnidium lactone 23.9mg, ferulic acid 42.0mg, su-fuling 2.7mg, liquiritin 36.3mg, isoliquiritin 17.0mg, astragaloside 6.7mg.The mixture effective ingredient is 252.3mg.

Comparing embodiment 56

Its operational approach and equipment are basic with comparing embodiment 45, only different is with the batching of pretreated embodiment 56 is raw material for 100 kilograms, contain in the fluid extract of its result by raw material 5 grams: Radix Ginseng general glycoside 19.3mg, cnidium lactone 13.9mg, ferulic acid 25.2mg, su-fuling 1.7mg, liquiritin 19.9mg, isoliquiritin 10.5mg, astragaloside 4.07mg.The mixture effective ingredient is 164.5mg.

Comparing embodiment 56

Its operational approach and equipment are basic with comparing embodiment 45, only different is with the batching of pretreated embodiment 56 is raw material for 100 kilograms, contain in the fluid extract of its result by raw material 5 grams: Radix Ginseng general glycoside 30.5mg, cnidium lactone 19.3mg, ferulic acid 32.9mg, su-fuling 2.3mg, liquiritin 30.5mg, isoliquiritin 13.5mg, astragaloside 5.9mg.The mixture effective ingredient is 216.3mg.

Embodiment 57

Its operational approach and equipment are substantially with embodiment 44, only different is by BAZHEN TANG, Radix Ginseng 3 grams, the Rhizoma Atractylodis Macrocephalae 3 grams, Poria 3 grams, Radix Angelicae Sinensis 3 grams, the Radix Paeoniae Alba 3 grams, Radix Rehmanniae Preparata 3 grams, Rhizoma Chuanxiong 3 grams, Radix Glycyrrhizae Preparata 1.5 grams, fresh ginger 3 grams, Fructus Jujubae 2 grams are prepared burden, with 100 kilograms of pretreated above-mentioned batchings is raw material, contain in the fluid extract of its result by raw material 5 grams: Radix Ginseng general glycoside 157.3mg, su-fuling 1.7mg, ferulic acid 62.0mg, paeoniflorin 26.0mg, paeoniflorin 15.3mg, paeonol 5.6mg, liquiritin 61.7mg.The mixture effective ingredient is 661.3mg.

Comparing embodiment 57

Its operational approach and equipment are basic with comparing embodiment 44, only different is with the batching of pretreated embodiment 57 is raw material for 100 kilograms, contain in the fluid extract of its result by raw material 5 grams: Radix Ginseng general glycoside 97.5mg, su-fuling 1.01mg, ferulic acid 32.6mg, paeoniflorin 16.5mg, paeoniflorin 10.3mg, paeonol 3.36mg, liquiritin 33.1mg.The mixture effective ingredient is 401.6mg.

Comparing embodiment 57

Its operational approach and equipment are basic with comparing embodiment 44, only different is with the batching of pretreated embodiment 57 is raw material for 100 kilograms, contain in the fluid extract of its result by raw material 5 grams: Radix Ginseng general glycoside 128.7mg, su-fuling 1.3mg, ferulic acid 49.6mg, paeoniflorin 20.6mg, paeoniflorin 12.5mg, paeonol 4.6mg, liquiritin 49.1mg.The mixture effective ingredient is 486.0mg.

Embodiment 58

Its operational approach and equipment are substantially with embodiment 44, only different is by eight delicacies with motherwort soup, Radix Ginseng 3.2 grams, Rhizoma Atractylodis Macrocephalae (parched) 3.2 grams, Poria 2.1 grams, Rhizoma Chuanxiong 2.1 grams, the Radix Paeoniae Alba 2.1 grams, Radix Angelicae Sinensis 2.1 grams, Radix Rehmanniae Preparata 2.1 grams, Radix Glycyrrhizae Preparata 2.1 grams, Herba Leonuri 5.6 grams are prepared burden, with 100 kilograms of pretreated above-mentioned batchings is raw material, contain in the fluid extract of its result by raw material 5 grams: Radix Ginseng general glycoside 63.2mg, su-fuling 0.7mg, ferulic acid 25.3mg, paeoniflorin 10.7mg, paeoniflorin 4.7mg, liquiritin 33.6mg, leonurine 3.9mg, stachydrine 31.5mg.The mixture effective ingredient is 347.2mg.

Comparing embodiment 58

Its operational approach and equipment are basic with comparing embodiment 44, only different is with the batching of pretreated embodiment 58 is raw material for 100 kilograms, contain in the fluid extract of its result by raw material 5 grams: Radix Ginseng general glycoside 33.5mg, su-fuling 0.45mg, ferulic acid 15.8mg, paeoniflorin 6.5mg, paeoniflorin 2.7mg, liquiritin 20.7mg, leonurine 2.1mg, stachydrine 19.5mg.The mixture effective ingredient is 213.7mg.

Comparing embodiment 58

Its operational approach and equipment are basic with comparing embodiment 44, only different is with the batching of pretreated embodiment 58 is raw material for 100 kilograms, contain in the fluid extract of its result by raw material 5 grams: Radix Ginseng general glycoside 48.2mg, su-fuling 0.57mg, ferulic acid 20.5mg, paeoniflorin 8.5mg, paeoniflorin 3.6mg, liquiritin 26.5mg, leonurine 3.2mg, stachydrine 25.5mg.The mixture effective ingredient is 270.5mg.

Embodiment 59

Its operational approach and equipment are substantially with embodiment 46, only different is by YINQIAO white tiger Zengye Tang, Rhizoma Anemarrhenae 14-28 gram (present embodiment is by 20 grams), Radix Glycyrrhizae 10.5 grams, the Radix Rehmanniae 35 grams, Semen oryzae sativae 17.5 grams, Flos Lonicerae 17.5 grams, Fructus Forsythiae 19.5-35 gram (present embodiment 25 grams), Radix Scrophulariae 35 grams, restrain Radix Ophiopogonis 28, fresh Rhizoma Imperatae 140 grams, Gypsum Fibrosum 28-70 gram (present embodiment 45 grams) is prepared burden, with 100 kilograms of pretreated above-mentioned batchings is raw material, contain in the fluid extract of its result by raw material 5 grams: zhimusaponin 15.3mg, chlorogenic acid 14.7mg, luteolin 14.8mg, lonicerin 24.2mg, glycyrrhizin 18.9mg, ursolic acid 35.9mg, oleanolic acid 15.6mg, Radix Ophiopogonis Saponin 28.6mg, Coixol 7.9mg.The mixture effective ingredient is 879.5mg.

Comparing embodiment 59

Its operational approach and equipment are basic with comparing embodiment 46, only different is with the batching of pretreated embodiment 59 is raw material for 100 kilograms, contain in the fluid extract of its result by raw material 5 grams: zhimusaponin 10.5mg, chlorogenic acid 8.7mg, luteolin 8.8mg, lonicerin 14.5mg, glycyrrhizin 12.1mg, ursolic acid 21.8mg, oleanolic acid 10.3mg, Radix Ophiopogonis Saponin 18.2mg, Coixol 4.9mg.The mixture effective ingredient is 623.5mg.

Comparing embodiment 59

Its operational approach and equipment are basic with comparing embodiment 46, only different is with the batching of pretreated embodiment 59 is raw material for 100 kilograms, contain in the fluid extract of its result by raw material 5 grams: zhimusaponin 13.4mg, chlorogenic acid 12.5mg, luteolin 12.6mg, lonicerin 21.3mg, glycyrrhizin 15.6mg, ursolic acid 32.5mg, oleanolic acid 14.5mg, Radix Ophiopogonis Saponin 25.6mg, Coixol 5.6mg.The mixture effective ingredient is 709.3mg.

Embodiment 60

Its operational approach and equipment are substantially with embodiment 44, only different is to press Radix Adenophorae (Radix Glehniae) silver chrysanthemum soup, Radix Adenophorae 15 grams, Radix Glehniae 15 grams, Flos Lonicerae 20 grams, Flos Chrysanthemi 10 grams, Herba Menthae 6 grams, Semen Armeniacae Amarum 10 grams, clear Radix Glycyrrhizae 2 grams are prepared burden, with 100 kilograms of pretreated above-mentioned batchings is raw material, contain in the fluid extract of its result by raw material 5 grams: triterpene saponin 28.7mg, daucosterol 17.5mg, ligustrin 9.6mg, chlorogenic acid 15.8mg, luteolin 5.3mg, chrysanthemum glycoside 6.3mg, menthone 18.6mg, amygdalin 12.8mg.The mixture effective ingredient is 525.5mg.

Comparing embodiment 60

Its operational approach and equipment are basic with comparing embodiment 44, only different is with the batching of pretreated embodiment 60 is raw material for 100 kilograms, contain in the fluid extract of its result by raw material 5 grams: triterpene saponin 18.0mg, daucosterol 10.5mg, ligustrin 5.76mg, chlorogenic acid 9.9mg, luteolin 3.3mg, chrysanthemum glycoside 3.2mg, menthone 12.6mg, amygdalin 7.8mg.The mixture effective ingredient is 275.2mg.

Comparing embodiment 60

Its operational approach and equipment are basic with comparing embodiment 44, only different is with the batching of pretreated embodiment 60 is raw material for 100 kilograms, contain in the fluid extract of its result by raw material 5 grams: triterpene saponin 25.6mg, daucosterol 15.8mg, ligustrin 8.3mg, chlorogenic acid 14.7mg, luteolin 4.2mg, chrysanthemum glycoside 5.6mg, menthone 17.4mg, amygdalin 11.58mg.The mixture effective ingredient is 421.0mg.

Embodiment 61

Its operational approach and equipment are substantially with embodiment 46, only different is by the detoxifcation heat clearing away cold decoction, Flos Lonicerae 30 grams, Fructus Forsythiae 30 grams, Flos Chrysanthemi 30 grams, Folium Mori 20 grams, Herba Menthae 15 grams, Radix Bupleuri 10 grams, Rhizoma Phragmitis 20 grams, Radix Scutellariae 15 grams, Radix Glycyrrhizae 15 grams, Periostracum Cicadae 15 grams, Gypsum Fibrosum 20-30 gram (present embodiment 25 grams), Talcum 20-30 gram (present embodiment 25 grams) is prepared burden, with 100 kilograms of pretreated above-mentioned batchings is raw material, contain in the fluid extract of its result by raw material 5 grams: chlorogenic acid 31.5mg, luteolin 14.6mg, forsythin 18.6mg, ursolic acid 17.8mg, oleanolic acid 20.6mg, glycyrrhizin 14.8mg, quercitrin 25.6mg, saikoside 18.7mg, Radix Bupleuri polysaccharide 29.6mg, baicalin 12.6mg.The mixture effective ingredient is 1022mg.

Comparing embodiment 61

Its operational approach and equipment are basic with comparing embodiment 46, only different is with the batching of pretreated embodiment 61 is raw material for 100 kilograms, contains in the fluid extract of its result by raw material 5 grams: chlorogenic acid 18.4mg, luteolin 8.6mg, forsythin 10.6mg, ursolic acid 11.1mg, oleanolic acid 12.2mg, glycyrrhizin 8.7mg, quercitrin 15.6mg, saikoside 10.5mg, Radix Bupleuri polysaccharide 19.6mg, baicalin 7.6mg.The mixture effective ingredient is 612mg.

Comparing embodiment 61

Its operational approach and equipment are basic with comparing embodiment 46, only different is with the batching of pretreated embodiment 61 is raw material for 100 kilograms, contains in the fluid extract of its result by raw material 5 grams: chlorogenic acid 28.3mg, luteolin 12.5mg, forsythin 17.3mg, ursolic acid 15.3mg, oleanolic acid 18.5mg, glycyrrhizin 12.5mg, quercitrin 21.8mg, saikoside 17.5mg, Radix Bupleuri polysaccharide 26.8mg, baicalin 11.4mg.The mixture effective ingredient is 822mg.

Embodiment 62

Its operational approach and equipment are substantially with embodiment 46, only different is to reach former Radix Bupleuri drink, Radix Bupleuri 15 grams, Semen Arecae 15 grams, Cortex Magnoliae Officinalis 10 grams, Fructus Tsaoko 10 grams, Radix Paeoniae Rubra 15 grams, Radix Scutellariae 15 grams, Radix Glycyrrhizae 5 grams, the Rhizoma Anemarrhenae 12 grams are prepared burden, with 100 kilograms of pretreated above-mentioned batchings is raw material, contain in the fluid extract of its result by raw material 5 grams: saikoside 14.8mg, Quercetin 22.9mg, Radix Bupleuri polysaccharide 38.6mg, zhimusaponin 25.8mg, magnolol 14.3mg, glycyrrhizic acid 18.9mg, arecoline 10.2mg, paeoniflorin 18.1mg, baicalin 15.8mg.The mixture effective ingredient is 852mg.

Comparing embodiment 62

Its operational approach and equipment are basic with comparing embodiment 46, only different is with the batching of pretreated embodiment 62 is raw material for 100 kilograms, contain in the fluid extract of its result by raw material 5 grams: saikoside 9.1mg, Quercetin 13.6mg, Radix Bupleuri polysaccharide 24.6mg, zhimusaponin 15.8mg, magnolol 8.9mg, glycyrrhizic acid 10.8mg, arecoline 6.2mg, paeoniflorin 10.5mg, baicalin 9.8mg.The mixture effective ingredient is 512mg.

Comparing embodiment 62

Its operational approach and equipment are basic with comparing embodiment 46, only different is with the batching of pretreated embodiment 62 is raw material for 100 kilograms, contain in the fluid extract of its result by raw material 5 grams: saikoside 13.6mg, Quercetin 21.5mg, Radix Bupleuri polysaccharide 33.5mg, zhimusaponin 21.7mg, magnolol 11.5mg, glycyrrhizic acid 14.6mg, arecoline 9.5mg, paeoniflorin 15.6mg, baicalin 14.7mg.The mixture effective ingredient is 702mg.

Embodiment 63

Press the loyal son side of the Radix Polygoni Multiflori, Radix Polygoni Multiflori 16 grams, Radix Rehmanniae Preparata 16 grams, Radix Achyranthis Bidentatae 16 grams, Fructus Ligustri Lucidi 16 grams, Fructus Mori 16 grams, field dobber 16 grams are prepared burden, and carry out pretreatment again as raw material.

With pretreated above-mentioned batching is raw material for 100 kilograms, adds entry in raw material, and the water yield that is added is 4 times of raw material weight, and heating extraction is 4 hours under the temperature of 70 ℃ of normal pressures, win time extracting solution and the medicinal residues first time.To the first time medicinal residues under the pressure of 1.5 kg/cm, carry out the breaking cellular wall squeezing first time, time press liquor and of winning for the first time through the medicinal residues of squeezing.Make medicinal residues loose in water to for the first time adding entry in the medicinal residues of squeezing, stirring, the water yield that is added is 4 times of raw material weight, carries out heating extraction 6 hours second time under the temperature of 65 ℃ of normal pressures, for the second time extracting solution and the second time medicinal residues.To the second time medicinal residues under the pressure of 5.0 kg/cm, carry out the breaking cellular wall squeezing second time, press liquor and for the second time through the medicinal residues of squeezing for the second time.To in the medicinal residues of squeezing, adding entry for the second time, stir and make medicinal residues loose in water, the water yield that is added is 4 times of material quantity, under the temperature of 45 ℃ of normal pressures, carried out for the third time heating extraction 4 hours, medicinal residues are for the third time carried out breaking cellular wall squeezing for the third time under the pressure of 5 kg/cm, press liquor and medicinal residues for the third time for the third time through squeezing.

The press liquor of the extracting solution of three merging and merging is for the third time filtered with the frame filter respectively, filtered extracting solution and press liquor are placed the concentrating under reduced pressure jar respectively, in pressure 0.065MPa, under 75 ℃ temperature, carry out concentrating under reduced pressure, make it be condensed into the fluid extract of proportion 1.20, fluid extract is mixed, contain in the fluid extract of its result by raw material 15 grams: chrysophanol 17mg, emodin 15mg, physcione 20mg, Radix Achyranthis Bidentatae acid 1.2mg, oleanolic acid 6.2mg, ursolic acid 9.8mg, Palmic acid 6.gmg, eigustroside 15.4mg, Quercetin 11.8mg.The mixture effective ingredient is 638.9mg.

Comparing embodiment 63: with the continuous extraction of application number 00107762.0

Its operational approach and equipment and embodiment 63 are basic identical, and only different is not carry out the breaking cellular wall squeezing after each heating extraction, and containing the mixture effective ingredient in the fluid extract of its structure by raw material 15 grams is 491.9mg.

Embodiment 64

Its operational approach and equipment are substantially with embodiment 63, only different is with Herba Menthae gold silver side, Herba Menthae 45 grams, Flos Lonicerae 45 grams are prepared burden, and are raw material with 100 kilograms of pretreated above-mentioned batchings, and containing the mixture effective ingredient in the fluid extract of its result by 15 grams is 582.4mg.

Comparing embodiment 64

Its operational approach and equipment are basic with embodiment 63 relatively, and only different is with the batching of pretreated embodiment 64 is raw material for 100 kilograms, and containing the mixture effective ingredient in the fluid extracts of its result by 15 grams is 463.2mg.

Embodiment 65

Its operational approach and equipment are substantially with embodiment 63, only different is with Cortex Eucommiae Fructus Schisandrae Chinensis side, the Cortex Eucommiae 25 grams, Fructus Schisandrae Chinensis 10 grams are prepared burden, and are raw material with 100 kilograms of pretreated above-mentioned batchings, and containing the mixture effective ingredient in the fluid extract of its result by raw material 15 grams is 578.9mg.

Comparing embodiment 65

Its operational approach and equipment are basic with embodiment 63 relatively, and only different is with the batching of pretreated embodiment 65 is raw material for 100 kilograms, and containing the mixture effective ingredient in the fluid extract of its result by raw material 15 grams is 480.5mg.

Embodiment 66

Its operational approach and equipment are substantially with embodiment 65, only different is with Rhizoma Polygonati Stigma Maydis side, Rhizoma Polygonati 6 grams, Stigma Maydis 20 grams are prepared burden, and are raw material with 100 kilograms of pretreated above-mentioned batchings, and containing the mixture effective ingredient in the fluid extract of its result by raw material 15 grams is 359.9mg.

Comparing embodiment 66

Its operational approach and equipment are basic with embodiment 63 relatively, and only different is with the batching of pretreated embodiment 66 is raw material for 100 kilograms, and containing the mixture effective ingredient in the fluid extract of its result by raw material 15 grams is 299.8mg.

Embodiment 67

Its operational approach and equipment are substantially with embodiment 63, only different is with stilbene Huang side, the Radix Astragali 18 restrains, Poria cum Radix Pini 18 restrains, withered root 18 restrains, Radix Glycyrrhizae 18 restrains, restrain Radix Ophiopogonis 18, Radix Rehmanniae 30 restrains and prepares burden, with 100 kilograms of pretreated above-mentioned batchings is raw material, and containing the mixture effective ingredient in the fluid extract of its result by raw material 15 grams is 678.5mg.

Comparing embodiment 67

Its operational approach and equipment are basic with embodiment 63 relatively, and only different is with the batching of pretreated embodiment 67 is raw material for 100 kilograms, and containing the mixture effective ingredient in the fluid extract of its result by raw material 15 grams is 532.5mg.

Embodiment 68

Its operational approach and equipment are substantially with embodiment 63, only different is with stilbene lotus side, Radix Astragali 30 grams, Herba Scutellariae Barbatae 20 grams, Herba Lobeliae Chinensis 20 grams, Radix Salviae Miltiorrhizae 20 grams are prepared burden, with 100 kilograms of pretreated above-mentioned batchings is raw material, and containing the mixture effective ingredient in the fluid extract of its result by raw material 15 grams is 569.0mg.

Comparing embodiment 68

Its operational approach and equipment are basic with embodiment 63 relatively, and only different is with the batching of pretreated embodiment 68 is raw material for 100 kilograms, and containing the mixture effective ingredient in the fluid extract of its result by raw material 15 grams is 456.5mg.

Embodiment 69

Its operational approach and equipment are substantially with embodiment 63, only different is with the heavy side of meat, Herba Cistanches 45 grams, Lignum Aquilariae Resinatum 22.5 grams are prepared burden, and are raw material with 100 kilograms of pretreated above-mentioned batchings, and containing the mixture effective ingredient in the fluid extract of its result by raw material 15 grams is 398.8mg.

Comparing embodiment 69

Its operational approach and equipment are basic with embodiment 63 relatively, and only different is with the batching of pretreated embodiment 69 is raw material for 100 kilograms, and containing the mixture effective ingredient in the fluid extract of its result by raw material 15 grams is 316.5mg.

Embodiment 70

Its operational approach and equipment are substantially with embodiment 63, only different is with Fructus Crataegi Radix Polygoni Multiflori side, Radix Polygoni Multiflori 40 grams, Fructus Crataegi 30 grams, Rhizoma Alismatis 22.5 grams are prepared burden, with 100 kilograms of pretreated above-mentioned batchings is raw material, and containing the mixture effective ingredient in the fluid extract of its result by raw material 15 grams is 654.6mg.

Comparing embodiment 70

Its operational approach and equipment are basic with embodiment 63 relatively, and only different is with the batching of pretreated embodiment 70 is raw material for 100 kilograms, and containing the mixture effective ingredient in the fluid extract of its result by raw material 15 grams is 523.5mg.

Embodiment 71

Its operational approach and equipment are substantially with embodiment 63, only different is with public region side, Radix Notoginseng 15 grams, Radix Salviae Miltiorrhizae 30 grams, Rhizoma Alismatis 22.5 grams, oligofructose 10 grams are prepared burden, with 100 kilograms of pretreated above-mentioned batchings is raw material, and containing the mixture effective ingredient in the fluid extract of its result by raw material 15 grams is 465.4mg.

Comparing embodiment 71

Its operational approach and equipment are basic with embodiment 63 relatively, and only different is with the batching of pretreated embodiment 71 is raw material for 100 kilograms, and containing the mixture effective ingredient in the fluid extract of its result by raw material 15 grams is 371.0mg.

Embodiment 72

Its operational approach and equipment are substantially with embodiment 63, only different is with Cortex Acanthopanacis Radicis five tastes side, Cortex Acanthopancis 15 grams, Fructus Schisandrae Chinensis 5 grams, oligofructose 2 grams are prepared burden, with 100 kilograms of pretreated above-mentioned batchings is raw material, and containing the mixture effective ingredient in the fluid extract of its result by raw material 15 grams is 1100mg.

Comparing embodiment 72

Its operational approach and equipment are basic with embodiment 63 relatively, and only different is with the batching of pretreated embodiment 72 is raw material for 100 kilograms, and containing the mixture effective ingredient in the fluid extract of its result by raw material 15 grams is 790.9mg.

Embodiment 73

Its operational approach and equipment are substantially with embodiment 63, only different is with Radix Polygoni Multiflori albumen side, the Radix Polygoni Multiflori 25 grams, Radix Salviae Miltiorrhizae 25 grams, Radix Puerariae 10 grams, oligofructose 4 grams are prepared burden, with 100 kilograms of pretreated above-mentioned batchings is raw material, and containing the mixture effective ingredient in the fluid extract of its result by raw material 15 grams is 420mg.

Comparing embodiment 73

Its operational approach and equipment are basic with embodiment 63 relatively, and only different is with the batching of pretreated embodiment 73 is raw material for 100 kilograms, and containing the mixture effective ingredient in the fluid extract of its result by raw material 15 grams is 331.2mg.

Embodiment 74

Its operational approach and equipment are substantially with embodiment 63, only different is with Radix Polygoni Multiflori Ganoderma side, the Radix Polygoni Multiflori 20 grams, Ganoderma 10 grams, oligofructose 2 grams, Radix Ginseng 5 grams, Cornu Cervi Pantotrichum 5 grams are prepared burden, with 100 kilograms of pretreated above-mentioned batchings is raw material, and containing the mixture effective ingredient in the fluid extract of its result by raw material 15 grams is 486.2mg.

Comparing embodiment 74

Its operational approach and equipment are basic with embodiment 63 relatively, and only different is with the batching of pretreated embodiment 74 is raw material for 100 kilograms, and containing the mixture effective ingredient in the fluid extract of its result by raw material 15 grams is 389.6mg.

Embodiment 75

Its operational approach and equipment are substantially with embodiment 63, only different is with Radix Polygoni Multiflori Radix Rehmanniae Preparata side, Radix Rehmanniae Preparata 30 grams, Lignum Aquilariae Resinatum 9 grams, the Radix Polygoni Multiflori 8 grams, Radix Angelicae Sinensis 25 grams, oligofructose 20 grams are prepared burden, with 100 kilograms of pretreated above-mentioned batchings is raw material, and containing the mixture effective ingredient in the fluid extract of its result by raw material 15 grams is 402mg.

Comparing embodiment 75

Its operational approach and equipment are basic with embodiment 63 relatively, and only different is with the batching of pretreated embodiment 75 is raw material for 100 kilograms, and containing the mixture effective ingredient in the fluid extract of its result by raw material 15 grams is 321.6mg.

Embodiment 76

Press Sang Ju Yin Fructus Pruni reed drink, Folium Mori 16 grams, Flos Chrysanthemi 13.5 grams, Semen Armeniacae Amarum 13 grams, fresh Rhizoma Phragmitis 17.5 grams are prepared burden, and carry out pretreatment again as raw material.

With pretreated above-mentioned batching is raw material for 100 kilograms, adds entry in raw material, and the water yield that is added is 7 times of raw material weight, and heating extraction is 8 hours under the temperature of 60 ℃ of normal pressures, win time extracting solution and the medicinal residues first time.To the first time medicinal residues under the pressure of 4.5 kg/cm, carry out the breaking cellular wall squeezing first time, time press liquor and of winning for the first time through the medicinal residues of squeezing.Make medicinal residues loose in water to for the first time adding entry in the medicinal residues of squeezing, stirring, the water yield that is added is 8 times of raw material weight, carries out heating extraction 5 hours second time under the temperature of 65 ℃ of normal pressures, for the second time extracting solution and the second time medicinal residues.To the second time medicinal residues under the pressure of 5 kg/cm, carry out the breaking cellular wall squeezing second time, press liquor and for the second time through the medicinal residues of squeezing for the second time.To in the medicinal residues of squeezing, adding entry for the second time, stir and make medicinal residues loose in water, the water yield that is added is 3 times of material quantity, under the temperature of 80 ℃ of normal pressures, carried out for the third time heating extraction 3 hours, medicinal residues are for the third time carried out breaking cellular wall squeezing for the third time under the pressure of 3.5 kg/cm, press liquor and medicinal residues for the third time for the third time through squeezing.

The press liquor of the extracting solution of three merging and merging is for the third time filtered with the frame filter, filtered extracting solution and press liquor are placed the concentrating under reduced pressure jar respectively, in pressure 0.065MPa, under 75 ℃ temperature, carry out concentrating under reduced pressure, make it be condensed into the fluid extract of proportion 1.20, contain in the fluid extract of its result by raw material 10 grams: Radix Achyranthis Bidentatae ketone 17.73mg, globulariacitrin 17.96mg, gynesin 82.30mg, flavone 0.26mg, vitamin E 0.32mg, amygdalin 0.20mg, Palmic acid 20.42mg, aspartic acid 10.63mg, threonine 1.90mg, glutamic acid 63.45mg.The mixture effective ingredient is 857.4mg.

Comparing embodiment 76

Its operational approach and equipment and embodiment 76 are basic identical, and only different is not carry out the breaking cellular wall squeezing after each heating extraction, and containing the mixture effective ingredient in the fluid extract of its structure by raw material 10 grams is 685.9mg.

Embodiment 77

Its operational approach and equipment and embodiment 76 are basic identical, only different is must to drink by the Rhizoma Zingiberis Recens Herba Alii fistulosi with beautiful, Stigma Maydis 9 grams, Rhizoma Zingiberis Recens 45 grams, Herba Alii fistulosi are prepared burden in right amount, with pretreated above-mentioned batching is raw material for 100 kilograms, and containing the mixture effective ingredient in the fluid extract of its structure by raw material 10 grams is 487.8mg.

Comparing embodiment 77

Its operational approach and equipment are basic with embodiment 76 relatively, and only different is with the batching of pretreated embodiment 77 is raw material for 100 kilograms, and containing the mixture effective ingredient in the fluid extract of its structure by raw material 10 grams is 390.2mg.

Embodiment 78

Its operational approach and equipment are substantially with embodiment 76, only different is with Herba Pogostemonis six at a draft, Herba Pogostemonis 10 grams, Talcum 10 grams, Radix Glycyrrhizae 3 grams are prepared burden, with pretreated above-mentioned batching is raw material for 100 kilograms, and containing the mixture effective ingredient in the fluid extract of its structure by raw material 10 grams is 228.1mg.

Comparing embodiment 78

Its operational approach and equipment are basic with embodiment 76 relatively, and only different is with the batching of pretreated embodiment 78 is raw material for 100 kilograms, and containing the mixture effective ingredient in the fluid extract of its structure by raw material 10 grams is 182.5mg.

Embodiment 79

Its operational approach and equipment are substantially with embodiment 76, only different is to drink with Herba Stachydis Japonicae, Talcum 10 grams, Radix Glycyrrhizae 3 grams, Herba Menthae 4.5 grams are prepared burden, and are raw material for 100 kilograms with pretreated above-mentioned batching, and containing the mixture effective ingredient in the fluid extract of its structure by raw material 10 grams is 682.6mg.

Comparing embodiment 79

Its operational approach and equipment are basic with embodiment 76 relatively, and only different is with the batching of pretreated embodiment 79 is raw material for 100 kilograms, and containing the mixture effective ingredient in the fluid extract of its structure by raw material 10 grams is 546.1mg.

Embodiment 80

Its operational approach and equipment are substantially with embodiment 76, only different is with ERCHEN TANG, the Rhizoma Pinelliae 25 grams, Pericarpium Citri Reticulatae 25 grams, Poria 15 grams are prepared burden, and are raw material for 100 kilograms with pretreated above-mentioned batching, and containing the mixture effective ingredient in the fluid extract of its structure by raw material 10 grams is 578.4mg.

Comparing embodiment 80

Its operational approach and equipment are basic with embodiment 76 relatively, and only different is with the batching of pretreated embodiment 80 is raw material for 100 kilograms, and containing the mixture effective ingredient in the fluid extract of its structure by raw material 10 grams is 462.7mg.

Embodiment 81

Its operational approach and equipment are substantially with embodiment 76, only different is to drink with teenage girl, Gypsum Fibrosum 10 grams, the Rhizoma Anemarrhenae 5 grams, the Radix Rehmanniae 10 restrain, restrain Radix Ophiopogonis 10, Radix Achyranthis Bidentatae 5 grams are prepared burden, with pretreated above-mentioned batching is raw material for 100 kilograms, and containing the mixture effective ingredient in the fluid extract of its structure by raw material 10 grams is 812.9mg.

Comparing embodiment 81

Its operational approach and equipment are basic with embodiment 76 relatively, and only different is with the batching of pretreated embodiment 81 is raw material for 100 kilograms, and containing the mixture effective ingredient in the fluid extract of its structure by raw material 10 grams is 650.3mg.

Embodiment 82

Its operational approach and equipment are substantially with embodiment 76, only different is to drink with Radix Saposhnikoviae, Radix Saposhnikoviae 19 grams, Radix Scutellariae 16 grams, Radix Gentianae Macrophyllae 16 grams, Semen Coicis 19 grams are prepared burden, with pretreated above-mentioned batching is raw material for 100 kilograms, and containing the mixture effective ingredient in the fluid extract of its structure by raw material 10 grams is 408.1mg.

Comparing embodiment 82

Its operational approach and equipment are basic with embodiment 76 relatively, and only different is with the batching of pretreated embodiment 82 is raw material for 100 kilograms, and containing the mixture effective ingredient in the fluid extract of its structure by raw material 10 grams is 326.4mg.

Embodiment 83

Its operational approach and equipment are substantially with embodiment 76, only different is with Herba Pogostemonis Rhizoma Zingiberis Recens soup, Herba Pogostemonis 30 grams, Rhizoma Zingiberis Recens 30 grams are prepared burden, and are raw material for 100 kilograms with pretreated above-mentioned batching, and containing the mixture effective ingredient in the fluid extract of its structure by raw material 10 grams is 947.4mg.

Comparing embodiment 83

Its operational approach and equipment are basic with embodiment 76 relatively, and only different is with the batching of pretreated embodiment 83 is raw material for 100 kilograms, and containing the mixture effective ingredient in the fluid extract of its structure by raw material 10 grams is 757.9mg.

Embodiment 84

Its operational approach and equipment are substantially with embodiment 76, only different is with the female drink of Fructus Pruni, the Rhizoma Anemarrhenae 16 grams, Semen Armeniacae Amarum 13 grams are prepared burden, and are raw material for 100 kilograms with pretreated above-mentioned batching, and containing the mixture effective ingredient in the fluid extract of its structure by raw material 10 grams is 728.5mg.

Comparing embodiment 84

Its operational approach and equipment are basic with embodiment 76 relatively, and only different is with the batching of pretreated embodiment 84 is raw material for 100 kilograms, and containing the mixture effective ingredient in the fluid extract of its structure by raw material 10 grams is 582.8mg.

Embodiment 85

Its operational approach and equipment are substantially with embodiment 76, only different is to drink with the Fructus Pruni chrysanthemum, Semen Armeniacae Amarum 13 grams, Flos Chrysanthemi 12 grams, wheat 12 grams are prepared burden, and are raw material for 100 kilograms with pretreated above-mentioned batching, and containing the mixture effective ingredient in the fluid extract of its structure by raw material 10 grams is 572.4mg.

Comparing embodiment 85

Its operational approach and equipment are basic with embodiment 76 relatively, and only different is with the batching of pretreated embodiment 85 is raw material for 100 kilograms, and containing the mixture effective ingredient in the fluid extract of its structure by raw material 10 grams is 457.9mg.

Embodiment 86

Its operational approach and equipment are substantially with embodiment 76, only different is to drink with Radix Salviae Miltiorrhizae, Radix Salviae Miltiorrhizae 16 grams, Lignum Santali Albi 4 grams are prepared burden, and are raw material for 100 kilograms with pretreated above-mentioned batching, and containing the mixture effective ingredient in the fluid extract of its structure by raw material 10 grams is 997.5mg.

Comparing embodiment 86

Its operational approach and equipment are basic with embodiment 76 relatively, and only different is with the batching of pretreated embodiment 86 is raw material for 100 kilograms, and containing the mixture effective ingredient in the fluid extract of its structure by raw material 10 grams is 798.0mg.

Claims (22)

1. the breaking cellular wall extracting method of Chinese crude drug and prescription is characterized in that,

1) with root, stem, skin, leaf, flower, fruit, the seed of natural medicinal plant, wherein a kind of of the medicinal part of natural medicinal animal, and press the required Chinese crude drug compositions of pharmaceutical formulation after pretreatment as raw material,

2) add entry in raw material, the mixing effective ingredient is extracted in heating under normal pressure, obtains extracting solution and medicinal residues for the first time for the first time,

3) to the first time medicinal residues under the pressure of 1.0～5.0 kg/cm, carry out the breaking cellular wall squeezing first time, time press liquor and of winning for the first time through the medicinal residues of squeezing,

4) make it loose in water to adding entry for the first time in the medicinal residues of squeezing, stirring, the extraction second time is carried out in heating under normal pressure, obtains extracting solution and medicinal residues for the second time for the second time,

5) to the second time medicinal residues under the pressure of 1.0～5.0 kg/cm, carry out the breaking cellular wall squeezing second time, press liquor and for the second time through the medicinal residues of squeezing for the second time,

6) make it loose in water in the medicinal residues of squeezing, adding entry for the second time, stirring, under normal pressure, heat and extract for the third time, get extracting solution and medicinal residues for the third time for the third time,

7) to medicinal residues for the third time under the pressure of 1.0～5.0 kg/cm, carry out breaking cellular wall squeezing for the third time, juicing and through the medicinal residues of squeezing for the third time for the third time,

8) extracting solution and press liquor are carried out concentrating under reduced pressure, make it be condensed into the fluid extract of proportion 1.10～1.35.

2. according to a kind of Chinese crude drug of claim 1 and the breaking cellular wall extracting method of prescription, it is characterized in that add entry in raw material, the water yield that is added is 4～10 times of raw material weight, under normal pressure under 30～100 ℃ temperature heating extraction 2-8 hour.

3. according to a kind of Chinese crude drug of claim 2 and the breaking cellular wall extracting method of prescription, it is characterized in that under 30～95 ℃ temperature heating extraction 4-8 hour.

4. according to a kind of Chinese crude drug of claim 1 and the breaking cellular wall extracting method of prescription, it is characterized in that, to in the medicinal residues of squeezing, adding entry for the first time, the water yield that is added is 2-8 a times of raw material weight, stir and make it loose in water, under normal pressure under 30～100 ℃ temperature heating extraction 2-6 hour.

5. according to a kind of Chinese crude drug of claim 4 and the breaking cellular wall extracting method of prescription, it is characterized in that under 30～95 ℃ temperature heating extraction 2-5 hour.

6. according to a kind of Chinese crude drug of claim 1 and the breaking cellular wall extracting method of prescription, it is characterized in that, to in the medicinal residues of squeezing, adding entry for the second time, the water yield that is added is 2-6 a times of raw material weight, stir and make it loose in water, under normal pressure under 30～100 ℃ temperature heating extraction 2-4 hour.

7. according to a kind of Chinese crude drug of claim 6 and the breaking cellular wall extracting method of prescription, it is characterized in that under 30～95 ℃ temperature heating extraction 2-4 hour.

8. according to a kind of Chinese crude drug of claim 1 and the breaking cellular wall extracting method of prescription, it is characterized in that, the extracting solution of three merging and the press liquor of three merging are filtered with the plate and frame filter.

9. the breaking cellular wall extracting method of a kind of Chinese crude drug according to Claim 8 and prescription is characterized in that, the press liquor after extracting solution after the filtration and the filtration carries out concentrating under reduced pressure respectively.

10. the breaking cellular wall extracting method of a kind of Chinese crude drug according to Claim 8 and prescription is characterized in that, carries out concentrating under reduced pressure after the press liquor after extracting solution after the filtration and the filtration merges.

11., it is characterized in that according to a kind of Chinese crude drug of claim 1 or 9 or 10 and the breaking cellular wall extracting method of prescription, at pressure 0.02～0.09MPa, carry out concentrating under reduced pressure under 30～90 ℃ the temperature, be concentrated into the fluid extract of proportion 1.10～1.35.

12., it is characterized in that according to a kind of Chinese crude drug of claim 11 and the breaking cellular wall extracting method of prescription, at pressure 0.02～0.09MPa, carry out concentrating under reduced pressure under 50～80 ℃ the temperature, be condensed into the fluid extract of proportion 1.10～1.20.

13. according to a kind of Chinese crude drug of claim 11 and the breaking cellular wall extracting method of prescription, it is characterized in that, with water vapour gas, compressed air, nitrogen a kind of gas wherein is atomization gas, fluid extract is carried out spray drying, the pressure of atomization gas is 0.1～1.0MPa, fluid extract is sprayed in the hot-air, and the temperature of hot-air is 40～400 ℃, forms the medicated powder granule.

14., it is characterized in that the pressure of atomization gas is 0.4～0.6MPa according to a kind of Chinese crude drug of claim 13 and the breaking cellular wall extracting method of prescription, the temperature of hot-air is 40～200 ℃.

15., it is characterized in that medicated powder average diameter of particles 1000-2000 μ m according to a kind of Chinese crude drug of claim 13 and the breaking cellular wall extracting method of prescription.

16. according to a kind of Chinese crude drug of claim 1 and the breaking cellular wall extracting method of prescription, it is characterized in that, will under 55～115 ℃ temperature, carry out drying through the medicinal residues of squeezing for the third time.

17., it is characterized in that exsiccant medicinal residues are ground into the medicinal residues fine powder, and the granularity that makes the medicinal residues fine powder was the 40-180 order according to a kind of Chinese crude drug of claim 16 and the breaking cellular wall extracting method of prescription.

18., it is characterized in that medicinal residues fine powder and the fluid extract of granularity being crossed 40-180 purpose medicinal residues gross weight 10-40% mix according to a kind of Chinese crude drug of claim 17 and the breaking cellular wall extracting method of prescription, form mixture.

19., it is characterized in that medicinal residues fine powder and the fluid extract of granularity being crossed 40-180 purpose medicinal residues gross weight 15-25% mix according to a kind of Chinese crude drug of claim 18 and the breaking cellular wall extracting method of prescription, form mixture.

20. according to a kind of Chinese crude drug of claim 18 or 19 and the breaking cellular wall extracting method of prescription, it is characterized in that, with water vapour gas, compressed air, nitrogen a kind of gas wherein is atomization gas, mixture is carried out spray drying, the pressure of atomization gas is 0.1～1.0MPa, mixture is sprayed in the hot-air, and the temperature of hot-air is 40～400 ℃, forms the medicated powder granule.

21., it is characterized in that the pressure of atomization gas is 0.4～0.6MPa according to a kind of Chinese crude drug of claim 20 and the breaking cellular wall extracting method of prescription, the temperature of hot-air is 40～200 ℃.

22., it is characterized in that medicated powder average diameter of particles 1000-2000 μ m according to a kind of Chinese crude drug of claim 20 and the breaking cellular wall extracting method of prescription.