CN101138398A - Medofenoxate and honey composition and method of producing the same - Google Patents

Medofenoxate and honey composition and method of producing the same Download PDF

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Publication number
CN101138398A
CN101138398A CNA2007100562329A CN200710056232A CN101138398A CN 101138398 A CN101138398 A CN 101138398A CN A2007100562329 A CNA2007100562329 A CN A2007100562329A CN 200710056232 A CN200710056232 A CN 200710056232A CN 101138398 A CN101138398 A CN 101138398A
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honey
composition
wilsonii
mixture
powder
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CNA2007100562329A
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徐海波
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Abstract

The present invention relates to a nutritious honey and the preparation method; the present invention in specific is a combination of acanthopanax and honey which has the health care function and the preparation method. The weights of components in the combination are that fine powder, superfines or one or a plurality of the extracts of the acanthopanax root, root stalk, stalk, leaf, fruit and flower account for 0.02 to 10.0 percent of the total weight and the honey accounts for 90.0 to 99.98 percent of the total weight; the present invention also discloses the preparation of the combination. The preparation method is that the fine powder, superfines or one or a plurality of the extracts of the acanthopanax root, root stalk, stalk, leaf, fruit and flower are added into honey and mixed evenly by a mixer. In the process of taking the honey, people can absorb the effective components of the acanthopanax root, which reduces the inconvenience of taking acanthopanax root separately and the simulation of acanthopanax root on people and enhances the health care function of honey.

Description

Wilsonii, honey composition and preparation method thereof
Technical field:
The present invention relates to a kind of nutraceutical with certain health-care effect and preparation method thereof, is exactly a kind of wilsonii with nutrition health-care functions, honey composition and preparation method thereof specifically.
Background technology
Along with the raising of people's living standard, the reaching its maturity of consumption concept, people are increasing to the demand of natural health type nutraceutical, require also more and more higher.
Honey belongs to traditional Chinese medicine of China and food, and use is extensive, market capacity is very big, and China also is maximum in the world bee product production and exported country.
2005 editions records of the Pharmacopoeia of the People's Republic of China, honey is flat, and it is sweet to distinguish the flavor of; Can bowl spares, moisturize, pain relieving, detoxifcation.Be used for the empty pain of abdomen gastral cavity, dryness of the lung dry cough, the dry constipation of intestines, can separate rhizome of Chinese monkshood poison; Control aphtha, sore, burn and scald outward; Consumption 15~30g.Modern pharmacology experimental results show that honey has inhibitory action to Escherichia coli, shigella dysenteriae, streptococcus, mould etc.; The surface of a wound there are convergence, nutrition and promotion healing effect; There is lubricity to eliminate the phlegm and laxative effective.
In recent years, China people honey amount constantly increases, but amount is still on the low side compared with developed countries.Except that the restriction of economic condition, mainly be because honey is a kind of nourishing agent of gentleness, slow for general disease or sub-health status onset, generally all to take for a long time just and can see obvious effects.And in the market except the Mel of routine, honey of various flowers, acacia honey, honey of lychee flowers, Mel Jujubae, chaste honey etc., also have rose honey, schisandra honey, motherwort honey, coptis honey, mother chrysanthemum nectar equal sign weighing-appliance that the honey of specific functionality is arranged, the supposition that produces but these functional honey are based on former plant medicinal efficacy more, actual pharmacological action there is no substantial evidence.
Therefore, honey still is a kind of notion of nutriment in people in the heart so far, and seldom expects its important identity as Chinese medicine.And in fact, honey has multiple pharmacological function, and is especially more remarkable to some common diseases and chronic disease effect.Therefore, deeply develop its purposes and will have boundless prospect as the functional food nutritious supplementary pharmaceutical.
Wilsonii is traditional northeast genunie medicinal materials, and wilsonii contains eleutheroside, compositions such as Hyperoside, 1-sesamin and polysaccharide.
Wilsonii can replenish qi to invigorate the spleen, and tonifies the kidney to relieve mental strain.Be used for that the insufficiency of both the spleen and the kindey, body void are weak, poor appetite, soreness of waist and knee joint, insomnia and dreamful sleep etc., have various health-care:
1. wilsonii has the adaptation former state effect of similar genseng.
2. the Isofraxidin that is contained has tangible sedation, and Hyperoside has ability and the sedation that improves the anti-hypobaric hypoxia of animal, and the acute myocardial ischemia that pituitrin is caused has protective effect.
3. Radix Et Caulis Acanthopanacis Senticosi polysaccharide has immunologic function and body detoxifcation, anti-infectious function etc.
Summary of the invention
The present invention utilizes special pharmacological action that wilsonii has and the gentleness that honey had nourishing characteristic, add to wilsonii powder or extract in the honey by a certain percentage, to strengthen the health-care efficacy of honey, reduce the honey dose, it is become have the clear and definite extra-nutrition effect and the wilsonii honey composition of health-care efficacy.Simultaneously, the made composition of the present invention can also solve the inconvenience of taking wilsonii separately, in the crowd who takes the honey custom is arranged, can be implemented in and replenishes acanthopanax nutrient under the situation that does not change original habits and customs, play and kill two birds with one stone, the effect of conveniently taking.
Wilsonii of the present invention, honey composition, be a kind of with ultra micro powder, fine powder or the above extractive part at positions such as the root of wilsonii, rhizome, stem, leaf, flower, fruit, or the mixture of above several materials adds in the honey by a certain percentage, then with blender or beat the mixings such as ultra micro powder, fine powder or its extract with positions such as the root of honey and wilsonii, rhizome, stem, leaf, flower, fruits such as the mixing machinery of mixing device, electronic mill, homogenizer, filter back can, encapsulation.
This preparation method who invents described siberian Ginseng P.E utilizes positions such as the root of wilsonii, rhizome, stem, leaf, flower, fruit as raw material, get other organic solvent that allows use in one or more raw material waters, alcohol or the food production wherein, use suitable extracting method and technology, adopt to reflux, ultrasonic, diacolation, decoction, microwave or methods such as conventional extracting method and supercritical extract extract its active ingredient, then further make liquid extract or make extract after drying.
Wilsonii of the present invention, honey composition have and replenish qi to invigorate the spleen, and the effect of tonifying the kidney to relieve mental strain has the adaptation former state effect of similar genseng; Myocardial ischemia there is protective effect, the detoxifcation of immunologic function and body, anti-infectious function etc. are arranged.
Wilsonii, honey composition are by gross weight, and it is composed as follows:
A) ultra micro powder, fine powder or the above extractive part at positions such as the root of the wilsonii of 0.02~10.0% (weight), rhizome, stem, leaf, flower, fruit is a kind of, or the mixture of the mixture of above several materials or different parts extract.
B) honey of 90.0~99.98% (weight).
Liquid honey raw material concentrated with low temperature after filtration make the honey that meets the commodity requirement, the certain proportion by the composition gross mass takes by weighing wilsonii powder or its extract then, earlier the wilsonii powder that takes by weighing or its extract etc. is joined in a spot of honey; Siberian Ginseng P.E also can dissolve by water, makes it become dense thick fluid paste.Then above obtained material is added in the honey, by grinding or blender, beat mixing machineries such as mixing device, electronic mill, homogenizer with its abundant mixing, thereby make wilsonii honey enriched mixture, filter afterwards, filter the back and in resulting wilsonii honey enriched mixture, continue to add an amount of honey, so that mixture reaches the ratio that needs, then with vortex mixer, agitator, blender, beat and mix device or mixing machineries such as electronic mill, homogenizer honey and wilsonii are concentrated sweet mixing, the vacuum froth breaking, canned packing gets final product.Or raw material honey mixed in proportion with siberian Ginseng P.E or superfine acanthopanax powder, fine powder etc., filtering then, low temperature concentrates, vacuum froth breaking, canned getting final product.Also honey elder generation can be filtered, concentrate, the mixture with wilsonii powder or extract or above material directly adds in the honey by a certain percentage then, with artificial or mechanical, filter mixings such as honey and wilsonii powder or extracts, and the vacuum froth breaking, can gets final product.If honey is solid-state, then one or more of solid bee honey and siberian Ginseng P.E, wilsonii powder or ultra micro powder can be mixed, spare matter, canned getting final product.
Wilsonii powder of the present invention or extract are meant extract a kind of of root, rhizome, stem, leaf, flower, fruit of ultra micro powder, fine powder or the wilsonii of root, rhizome, stem, leaf, flower, fruit of wilsonii etc. etc., or the mixture of above several materials.The preparation method of wilsonii powder is one or more the mixture with the root of wilsonii, rhizome, stem, leaf, flower, fruit, by machineries such as electric mill, pulverizer, whirlpool pulverizers it is ground into fine powder or superfine powder, ultra micro powder.The preparation method of siberian Ginseng P.E is other organic solvent that will allow on water, alcohol or the food such as the root of wilsonii, rhizome, stem, leaf, flower, fruit to use, utilize suitable extracting method, adopt to reflux, ultrasonic, diacolation, decoction, microwave or methods such as conventional extracting method and supercritical extract extract, make liquid extract or make extract after drying.
Honey of the present invention is meant one or more the mixture in the honey such as Mel, honey of various flowers, Mel Jujubae, acacia honey, honey of lychee flowers, rape nectar, rose nectar, motherwort honey, schisandra honey, Radix Astragali honey, lily feet nectar, coptis honey, mother chrysanthemum nectar, Radix Codonopsis honey, chaste honey, matrimony vine honey, clover honey, lotus honey, or allows the additive that uses or the auxiliary material further liquid or solid that obtains of processing or the honey of powdery by above honey on the food such as dextrin, starch, glucose, fructose, cellulose, vitamin through adding.
The specific embodiment:
With one or more the mixture of the root of wilsonii, rhizome, stem, leaf, flower, fruit etc., by machineries such as electric mill, pulverizer, whirlpool pulverizers it is ground into fine powder or superfine powder, ultra micro powder, make the wilsonii powder.
Allow other organic solvent of using on one or more mixture water, alcohol or the food with the root of wilsonii, rhizome, stem, leaf, flower, fruit etc., with reflux, ultrasonic, diacolation, decoction, microwave or methods such as conventional extracting method and supercritical extract extract, make liquid extract or make extract after drying.
Liquid honey raw material concentrated with low temperature after filtration make the honey that meets the commodity requirement, the certain proportion by the honey gross mass takes by weighing wilsonii powder or its extract then, earlier the wilsonii powder that takes by weighing or its extract etc. is joined in a spot of honey; Siberian Ginseng P.E also can dissolve by water, makes it become dense thick fluid paste.Then above obtained material is added in the honey, by grinding or blender, beat mixing machineries such as mixing device, electronic mill, homogenizer with its abundant mixing, thereby make wilsonii honey enriched mixture, filter afterwards, filter the back and in resulting wilsonii honey enriched mixture, continue to add an amount of honey, so that mixture reaches the ratio that needs, then with vortex mixer, agitator, blender, beat and mix device or mixing machineries such as electronic mill, homogenizer honey and wilsonii are concentrated sweet mixing, the vacuum froth breaking, canned packing gets final product.Or raw material honey mixed in proportion with siberian Ginseng P.E or superfine acanthopanax powder, fine powder etc., filtering then, low temperature concentrates, canned getting final product.Also honey elder generation can be filtered, concentrate, the mixture with wilsonii powder or extract or above material directly adds in the honey by a certain percentage then, with artificial or mechanical with mixings such as honey and wilsonii powder or extracts, and the vacuum froth breaking, can gets final product.If honey is solid-state, then one or more of solid bee honey and siberian Ginseng P.E, wilsonii powder or ultra micro powder can be mixed, spare matter, canned getting final product.
Can prepare by following process specifically: with the Radix Acanthopanacis Senticosi root of drying, rhizome or stem, leaf, really, 1000 grams such as flower, be ground into meal about 20 orders with pulverizer, water or ethanol or other solvent extraction, extracting liquid filtering, it is dry to concentrate the back, make and by siberian Ginseng P.E powder 100 grams of 100 mesh sieves 10000 gram honey to be joined in the electric mixer, machine then, ratio in 1.0% slowly adds siberian Ginseng P.E, stir while adding, honey and siberian Ginseng P.E are mixed, mixture is produced by the even matter effect of the stirring of electric mixer, filter, the filtering insoluble matter, vacuum froth breaking, canned getting final product.
Composition of the present invention is characterized in that the content of wilsonii composition contains 0.02~10.0% by weight, preferably 0.05~5.0%, further preferably 0.1~2.0%, and most preferably be 0.2~1.0%.
Embodiment one:
A kind of composition that contains wilsonii and honey, it is characterized in that in gross weight wherein the ratio of components of raw material be:
A) ultra micro powder, fine powder or the above extractive part at positions such as the root of the wilsonii of 0.02~10.0% (weight), rhizome, stem, leaf, flower, fruit is a kind of, or the mixture of above several materials.
B) honey of 90.0-99.98% (weight).
Embodiment two:
A kind of composition that contains wilsonii and honey, it is characterized in that in gross weight wherein the ratio of components of raw material be:
A) ultra micro powder, fine powder or the above extractive part at positions such as the root of the wilsonii of 0.05~5.0% (weight), rhizome, stem, leaf, flower, fruit is a kind of, or the mixture of above several materials.
B) honey of 95.0~99.95% (weight).
Embodiment three:
A kind of composition that contains wilsonii and honey, it is characterized in that in gross weight wherein the ratio of components of raw material be:
A) ultra micro powder, fine powder or the above extractive part at positions such as the root of the wilsonii of 0.1~2.0% (weight), rhizome, stem, leaf, flower, fruit is a kind of, or the mixture of above several materials.
B) honey of 98.0~99.9% (weight).
Embodiment four:
A kind of composition that contains wilsonii and honey, it is characterized in that in gross weight wherein the ratio of components of raw material be:
A) ultra micro powder, fine powder or the above extractive part at positions such as the root of the wilsonii of 0.2~1.0% (weight), rhizome, stem, leaf, flower, fruit is a kind of, or the mixture of above several materials.
B) honey of 99.0~99.8% (weight).
Embodiment five:
A kind of composition that contains wilsonii and honey, it is characterized in that in gross weight wherein the ratio of components of raw material be:
A) ultra micro powder, fine powder or the above extractive part at positions such as the root of the wilsonii of 0.4-0.8% (weight), rhizome, stem, leaf, flower, fruit is a kind of, or the mixture of above several materials.
B) honey of 99.2-99.6% (weight).

Claims (10)

1. the composition that contains wilsonii and honey, it is characterized in that it contains the wilsonii composition of 0.02~10.0% (weight), this wilsonii composition can be powder of Radix Acanthopanacis Senticosi root, rhizome, stem, leaf, flower, fruit or one or more the mixture in the ultra micro powder, or extracts the extract that obtains by one or more mixture of above raw material; And containing auxiliary materials such as the dextrin that allows on the honey of 90.0~99.98% (weight) or the food to use, fructose, glucose, above-mentioned content is in the gross weight of said composition.
2. according to the composition of claim 1, the content that it is characterized in that above-mentioned wilsonii composition is to count 0.02~10.0% (weight) with composition total weight.
3. according to the composition of claim 1~2, it is characterized in that it contains 90.0~99.98% honey, this honey is meant Mel, honey of various flowers, Mel Jujubae, acacia honey, honey of lychee flowers, rape nectar, rose nectar, motherwort honey, schisandra honey, wilsonii honey, lily feet nectar, coptis honey, mother chrysanthemum nectar, Radix Codonopsis honey, chaste honey, matrimony vine honey, clover honey, the mixture of one or more in the honey such as lotus honey, or by above honey through adding dextrin, starch, converted starch, glucose, fructose, cellulose, the liquid or solid that the further processing of additive that permission is used on the food such as vitamin or auxiliary material obtains or the honey of powdery.
4. according to the composition of claim 1~3, the content that it is characterized in that the wilsonii composition by weight preferably 0.05~5.0%, further preferably 0.1~2.0%, most preferably be 0.2~1.0%.
5. require described composition according to arbitrary in the claim 1~4, it is characterized in that it is 99.0~99.98% the honey or the mixture and the converted products of various honey by weight that said composition contains, preferably 95.0~99.95%, further preferably 98.0~99.9%, most preferably be 99.0~99.8%.
6. according to the described composition of arbitrary claim in aforementioned 1~5 claim, it is characterized in that not changing under the prerequisite that honey is main component, can also add on the food to allow the various additives that use or auxiliary material such as glucose, cellulose, sucrose, dextrin, starch, converted starch etc. by a certain percentage.
7. according to the described composition of arbitrary claim in aforementioned 1~6 claim, its preparation method and process are as follows: with Radix Acanthopanacis Senticosi root, rhizome, stem, leaf, flower, really, or the mixture of above raw material, make the ultra micro powder, superfine powder, or water, the organic solvent that allows on alcohol or other food, make extract with backflow or methods such as conventional extracting method and supercritical extract, be added in proportion in a small amount of honey, by making enriched mixture after grinding or the even matter of homogenizer tool, add honey then and be diluted to and need ratio before can, agitator or homogenizer tool mixing filter, the vacuum froth breaking, canned packing gets final product; Also can be directly the fine powder of wilsonii or ultra micro powder or extract be added in the honey in proportion, by grind or the even matter of homogenizer tool after make mixture, filter can behind the vacuum froth breaking.
Can prepare by following process specifically: with the Radix Acanthopanacis Senticosi root of drying, rhizome or stem, leaf, really, 1000 grams such as flower, be ground into meal about 20 orders with pulverizer, water or ethanol or other solvent extraction, carrying body fluid filters, it is dry to concentrate the back, make and by siberian Ginseng P.E powder 100 grams of 100 mesh sieves 10000 gram honey to be joined in the electric mixer, machine then, ratio in 1.0% slowly adds siberian Ginseng P.E, stir while adding, honey and siberian Ginseng P.E are mixed, mixture is produced by the even matter effect of the stirring of electric mixer, filter, the filtering insoluble matter, vacuum froth breaking, canned getting final product.
8. according to the described wilsonii of claim 1~7, honey composition, contain:
A) 95.0~99.95% honey
B) 0.05~5.0% wilsonii composition
9. according to the described wilsonii of claim 1~7, honey composition, contain:
A) 97.0~99.9% honey
B) 0.1~3.0% wilsonii composition
10. according to the described wilsonii of claim 1-7, honey composition, contain:
A) 99.0~99.8% honey
B) 0.2~1.0% wilsonii composition.
CNA2007100562329A 2007-10-29 2007-10-29 Medofenoxate and honey composition and method of producing the same Pending CN101138398A (en)

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101766246A (en) * 2009-12-31 2010-07-07 邵伟 Radix acanthopanacis senticosi northern (southern) five-flavor American ginseng tea
CN102283340A (en) * 2010-06-21 2011-12-21 吉林省鼎健天然植物基地有限公司 Nutrition enriched honey
CN102669675A (en) * 2011-03-11 2012-09-19 田敬华 Production technology of sessileflower acanthopanax bark deep processed products
CN104223300A (en) * 2014-09-18 2014-12-24 哈药集团三精制药股份有限公司 Oral liquid capable of relieving physical fatigue and improving sleep and preparation method of oral liquid
CN104256245A (en) * 2014-10-14 2015-01-07 张明超 Radix codonopsis and honey composition and preparation method thereof
CN108497082A (en) * 2017-06-16 2018-09-07 北京工业大学 The formula and preparation method of two kinds of wilsonii solid beverages

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101766246A (en) * 2009-12-31 2010-07-07 邵伟 Radix acanthopanacis senticosi northern (southern) five-flavor American ginseng tea
CN101766246B (en) * 2009-12-31 2012-11-21 邵伟 Radix acanthopanacis senticosi northern (southern) five-flavor American ginseng tea
CN102283340A (en) * 2010-06-21 2011-12-21 吉林省鼎健天然植物基地有限公司 Nutrition enriched honey
CN102669675A (en) * 2011-03-11 2012-09-19 田敬华 Production technology of sessileflower acanthopanax bark deep processed products
CN104223300A (en) * 2014-09-18 2014-12-24 哈药集团三精制药股份有限公司 Oral liquid capable of relieving physical fatigue and improving sleep and preparation method of oral liquid
CN104256245A (en) * 2014-10-14 2015-01-07 张明超 Radix codonopsis and honey composition and preparation method thereof
CN108497082A (en) * 2017-06-16 2018-09-07 北京工业大学 The formula and preparation method of two kinds of wilsonii solid beverages

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Application publication date: 20080312