CN1327841A - Medicine for treating rheumatoid arthritis - Google Patents
Medicine for treating rheumatoid arthritis Download PDFInfo
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Abstract
A Chinese medicine for treating rheumatoid arthritis is prepared from 48 Chinese-medicinal materials including fleece flower root, pilose asiabell root, Chinese angelica root, astragalus root, etc. through proportioning. Its advantages is high curative effect.
Description
The present invention relates to a kind of medicine for the treatment of rheumatoid arthritis.
Rheumatoid arthritis is the commonly encountered diseases of serious harm human health, and at present the patient of rheumatoid arthritis surpasses 200,000,000 people in the world, and China is near 10,000,000, and the trend that increases is year by year arranged.Rheumatoid arthritis is a kind of chronic that show effect repeatedly, systemic disease based on arthritis.The migration arthralgia is arranged in early days, and swelling and dysfunction then show as ankylosis and lopsided, afunction late period, cause the maimed person.Pathological changes is mainly at synovium of joint, secondly for the trend of spontaneous remission is arranged behind histoorgan, the small part patients such as serous coat, cardiopulmonary and eye, skin, blood vessel, liver,kidney,spleen, most patient's state of an illness are heavy when light repeatedly the time, and other has the small part patient state of an illness to be to continue aggravation, the time have static.This disease law of development can be summarized as: arthroncus this disappear that rises, arthralgia this heavy that are light, these right those volts of arthritis, touching years.If can not control or cure.Disable at last.
Treatment runs into following thorny problem to medicine for treating rheumatoid arthritis both at home and abroad at present:
1, application Western medicine one line medicine class, gastrointestinal tract have untoward reaction.Inappetence in various degree, epigastric discomfort, vomiting and diarrhoea.Taking for a long time has untoward reaction to hemogram regulating liver-QI, renal function.
2, use Western medicine two wires medicine class, can cause untoward reaction such as oral ulcer, platelet and leukopenia can take place, aplastic anemia.
3, use the untoward reaction that the glucocorticoid medicine can cause cortex, sclerotin and mental symptom.
Though the Chinese patent medicine of some treatment rheumatoid arthritiss is also arranged, because DeGrain, the patient still has to depend on some Western medicine.
The object of the present invention is to provide a kind of strengthening vital QI to eliminate pathogenic factors that has, treating both the principal and secondary aspects of a disease, bone and muscle strengthening, enhancing human body immunity power promote the body tissue reparation, regenerate or the state of an illness is controlled and the medicament of the treatment rheumatoid arthritis alleviated.
Solution of the present invention is based on understanding and the Therapeutic Principle of motherland's medical science to rheumatoid arthritis mechanism, draws historical physician's medical treatment and the clinical experience of self, achieves with reference to modern pharmacological research.The blood-supplementing blood-nourishing blood circulation promoting and blood stasis dispelling that from the medical treasure-house of motherland, screens, treating blood disorders circulation of qi promoting, dispelling cold by warming the meridian, dredging the meridian, expelling wind and removing dampness, dephlogistication and promoting nuscle growth, nourishing the liver and kidney, spleen invigorating, the natural plants of QI invigorating mind calming, biological raw material, by the theory of Chinese medical science prescription, make its performance treating both the principal and the secondary aspects of a disease at the same time, strong muscles and bones, enhancing human body resistance against diseases play the effect of " strengthening vital QI to eliminate pathogenic factors " treatment rheumatoid arthritis.
The present invention makes (consumption is a weight portion) by following component
(a) basic medicament: fleece-flower root 9-15 Radix Codonopsis 10-30 Radix Angelicae Sinensis 9-30 gives birth to the windproof 3-10 bark of ash of Radix Astragali 9-45 sealwort 9-30 bighead atractylodes rhizome 7-15 rhizoma cibotii 3-9 scorpio 1.2-6 earthworm 5-15 zaocys dhumnade 1.5-9 ant 3-20 red sage root 5-30 ramulus mori 15-60 cassia twig 3-30 rhizoma atractylodis 5-12 notopterygium root 3-10 levisticum 3-10 3-18 parasitic loranthus 10-20 bark of eucommia 6-30 radix cyathulae 6-30 golden cypress 3-12 rhizoma homalonemae 3-15 and bores the sub-9-25 corydalis tuber of ground maple 3-15 frankincense 3-15 myrrh 3-15 caulis sinomenii 9-15 rhizoma arisaematis 3-15 reticulate millettia 10-60 mulberries 3-9 Ligusticum wallichii 3-12 jujube kernel 10-18 wind-weed 6-25 Poria cocos 9-45 aconiti preparata,radix 3-30 HERBA EPIMEDII 6-12 safflower 3-10 Radix Glycyrrhizae 3-30
(b) plus-minus raw material: cold very person add Radix Aconiti Kusnezoffii Preparata 3-30 Radix Dipsaci 6-30 Radix Astragali Mongolici (processed) 9-45 subtract Radix Astragali 9-45 heat very the person add Cortex Moutan 10-30 Caulis Lonicerae 10-80 Radix Paeoniae Rubra 6-15 Semen Coicis 6-30 Cortex erythrinae 6-12 Caulis Trachelospermi 6-15 and subtract Radix Aconiti Preparata 3-30
Formula optimization weight (part) ratio range of preparation medicine of the present invention is:
(a) basic medicament: fleece-flower root 10-15 Radix Codonopsis 10-25 Radix Angelicae Sinensis 10-20 gives birth to the windproof 3-9 bark of ash of Radix Astragali 10-25 sealwort 10-30 bighead atractylodes rhizome 7-12 rhizoma cibotii 4.5-9 scorpio 3-6 earthworm 6-12 zaocys dhumnade 3-9 ant 5-20 red sage root 6-20 ramulus mori 15-60 cassia twig 6-20 rhizoma atractylodis 5-12 notopterygium root 3-9 levisticum 3-10 5-15 parasitic loranthus 10-15 bark of eucommia 10-30 radix cyathulae 6-20 golden cypress 3-10 rhizoma homalonemae 5-12 and bores the sub-9-25 corydalis tuber of ground maple 5-15 frankincense 3-12 myrrh 3-12 caulis sinomenii 9-12 rhizoma arisaematis 3-10 reticulate millettia 15-40 mulberries 5-9 Ligusticum wallichii 3-10 jujube kernel 12-18 wind-weed 6-15 Poria cocos 9-30 aconiti preparata,radix 6-12 HERBA EPIMEDII 8-12 safflower 6-10 Radix Glycyrrhizae 3-10
(b) plus-minus raw material: cold very person add Radix Aconiti Kusnezoffii Preparata 6-12 Radix Dipsaci 9-15 Radix Astragali Mongolici (processed) 10-25 subtract Radix Astragali 10-25 heat very the person add Cortex Moutan 15-25 Caulis Lonicerae 12-30 Radix Paeoniae Rubra 8-15 Semen Coicis 10-30 Cortex erythrinae 8-12 Caulis Trachelospermi 10-15 and subtract Radix Aconiti Preparata 6-12
The optimum weight of medicine of the present invention (part) proportioning is:
(a) basic medicament: the fleece-flower root 15 Radix Codonopsis 18 Radix Angelicae Sinensis 15 are given birth to the Radix Astragali 20 sealworts 20 bighead atractylodes rhizomes 12 rhizoma cibotii 6 scorpios 6 earthworms 10 zaocys dhumnades 9 ants 12 reds sage root 15 ramulus moris 30 cassia twig 9 rhizoma atractylodis 10 notopterygium roots 9 levisticums 9 windproof 8 bark of ash, 15 parasitic loranthus, 15 barks of eucommia, 20 radix cyathulaes, 15 golden cypresses, 9 rhizoma homalonemaes 10 and are bored ground maple 10 frankincenses 8 myrrhs 8 caulis sinomeniis 10 rhizoma arisaematis 9 reticulate millettias 30 mulberries 12 corydalis tubers 9 Ligusticum wallichiis 10 jujube kernels 15 wind-weeds 10 Poria cocos 15 aconiti preparata,radixs 9 HERBA EPIMEDIIs 10 safflowers 10 Radix Glycyrrhizaes 6
(b) plus-minus raw material: cold very person add Radix Aconiti Kusnezoffii Preparata 9 Radix Dipsacis 12 Radix Astragali Mongolici (processed) 20 subtract Radix Astragali 20 heat very the person add Cortex Moutan 18 Caulis Loniceraes 15 Radix Paeoniae Rubra 10 Semen Coiciss 18 Cortex erythrinaes 10 Caulis Trachelospermis 12 and subtract Radix Aconiti Preparata 9
Although rheumatoid arthritis performance is complicated, finding mostly is the cold and heat two ends, and it is in the majority to belong to cold person, and the present invention be cold partially double pattern of fever, during use for the rheumatoid arthritis very person of person or heat that trembles with fear very, the corresponding medicament of available the present invention.
Characteristics of the present invention are that QI and blood regulating and wind-damp dispelling develop simultaneously, and deficiency and excess is taken into account, together to set upright.Follow the principle of " the eliminating evil healthy energy of not hindering is set upright in order to rehabilitation ",, regulate the flow of vital energy dephlogistication and promoting nuscle growth with Radix Polygoni Multiflori, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, Flos Carthami, Olibanum, Myrrha, Rhizoma Chuanxiong, Rhizoma Corydalis, Radix Dipsaci, Cortex Moutan, Radix Cyathulae, the blood stasis dispelling of Radix Paeoniae Rubra blood-supplementing blood-nourishing removing heat from blood and promoting blood circulation; With the Radix Astragali, Rhizoma Polygonati, Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, Semen Ziziphi Spinosae, the nourishing the heart to keep a sound mind that fills blood, benefiting qi and raising yang, Yin-nourishing and body fluid promoting, the profit cardiopulmonary; With Radix Angelicae Pubescentis, Rhizoma Et Radix Notopterygii, Radix Saposhnikoviae, Ramulus Cinnamomi, Radix Aconiti, Radix Aconiti Kusnezoffii, the Rhizoma Arisaematis cold expelling that induces sweat, expelling wind and removing dampness, warming the meridian clearing away phlegm, reducing swelling and alleviating pain; With Scorpio, Zaocys, Formica fusca, Pheretima, Caulis Spatholobi,, Cortex erythrinae, Radix Gentianae Macrophyllae, Caulis Sinomenii, Ramulus Mori, Rhizoma Homalomenae, brill Cortex Illici difengpi dredge the meridian passage wind-damp dispelling, sharp joint, row aqueous vapor, the diuresis of relievining asthma; With Caulis Trachelospermi, Cortex Phellodendri, the Rhizoma Anemarrhenae, Caulis Lonicerae, Semen Coicis heat-clearing and toxic substances removing, eliminating dampness and dredging channels; With Herba Taxilli, Rhizoma Cibotii, Fructus Mori, Rhizoma Atractylodis, Poria, the Cortex Eucommiae, Herba Epimedii invigorating the liver and kidney, strengthening the spleen and stomach, supporing yang benefit is smart, bone and muscle strengthening.The Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription.
Among the present invention, the modern study pharmacological evaluation proves that Rhizoma Chuanxiong, Cortex Moutan, Radix Polygoni Multiflori, Radix Angelicae Pubescentis be blood vessel dilating directly, and coronary artery blood flow and lower extremity blood flow amount are increased; Radix Polygoni Multiflori, Radix Salviae Miltiorrhizae, the Radix Astragali, Rhizoma Polygonati, the Cortex Eucommiae, Caulis Spatholobi, Radix Glycyrrhizae, Herba Epimedii, Semen Coicis have conciliation, two-way conciliation effect to body's immunity, promote human body energy metabolism and anabolic reaction, enhancing body tissue repair and regeneration, Radix Salviae Miltiorrhizae, Flos Carthami, Radix Angelicae Sinensis, Herba Taxilli can be adjusted blood system, reduce platelet aggregation, anticoagulant, accelerate the microcirculation velocity of blood flow, it is open to increase capillary network; Radix Angelicae Sinensis also has significant promote hemoglobin and erythrocytic generation, promotes the non-specific immunity effect; Rhizoma Chuanxiong, Rhizoma Corydalis, Caulis Sinomenii, Radix Gentianae Macrophyllae, Herba Taxilli have obvious suppression and the effect of paralysis nerve centre; The Rhizoma Atractylodis Macrocephalae, the Cortex Eucommiae can strengthen the phagocytic function of monokaryon-macrophage; Formica fusca contains energy-rich compound, the ATP steroid, and multiple free amino acid, zinc content is abundant.
The present invention has tangible analgesia, calmness, antitussive, antiinflammatory, antibiotic, analgesic, effect.Hypnosis, diuresis, heart tonifying, hypotensive effect are arranged.
The present invention uses the result to show, following advantage is arranged:
1, to select natural plants, biological Chinese medicine for use be raw material in the present invention, and each component meets the pharmaceutical control law regulation.Adopt the comprehensive function treatment rheumatoid arthritis of the Chinese medicine of respectively distinguishing the flavor of, have no side effect
2, the present invention can be made into dosage forms such as powder, pill, tablet, capsule, decoction, especially suitable medicated wine.
3, the lighter and just do not send out the person.Can use basic medicament of the present invention separately, cold very person or heat very person can be used its corresponding medicament, and therapeutic effect is fairly obvious, and can alleviate, eliminate other complication.
The present invention is to the therapeutic effect of rheumatoid arthritis, through the age 17 to 78 years old, 6 months to 42 years totally 100 row patients of the course of disease, selectively use according to medical history.Obey 2 times instructions of taking: 6-9 gram/time, day, the breakfast clothes 1 hour after meal evening before yesterday.Observation period: the lighter or just not send out the person be a course of treatment every month, took 3 months, for a long time sick and serious symptom person is a course of treatment every month, takes 6 months, and that obtains significant curative effect accounts for 67%, effectively accounts for 33%, and effective percentage reaches 100%.
Claims (4)
1, a kind of medicine for the treatment of rheumatoid arthritis is characterized in that it is the medicament of being made by the following weight proportion raw material.
(a) basic medicament: fleece-flower root 9-15 Radix Codonopsis 10-30 Radix Angelicae Sinensis 9-30 gives birth to the windproof 3-10 bark of ash of Radix Astragali 9-45 sealwort 9-30 bighead atractylodes rhizome 7-15 rhizoma cibotii 3-9 scorpio 1.2-6 earthworm 5-15 zaocys dhumnade 1.5-9 ant 3-20 red sage root 5-30 ramulus mori 15-60 cassia twig 3-30 rhizoma atractylodis 5-12 notopterygium root 3-10 levisticum 3-10 8-18 parasitic loranthus 10-20 bark of eucommia 6-80 radix cyathulae 6-30 golden cypress 8-12 rhizoma homalonemae 3-15 and bores the sub-9-25 corydalis tuber of ground maple 3-15 frankincense 3-16 myrrh 3-15 caulis sinomenii 9-16 rhizoma arisaematis 3-15 reticulate millettia 10-60 mulberries 3-9 Ligusticum wallichii 3-12 jujube kernel 10-18 wind-weed 6-26 Poria cocos 9-45 aconiti preparata,radix 3-30 HERBA EPIMEDII 6-12 safflower 3-10 Radix Glycyrrhizae 8-80
(b) plus-minus raw material: cold very person add Radix Aconiti Kusnezoffii Preparata 8-80 Radix Dipsaci 6-30 Radix Astragali Mongolici (processed) 9-45 subtract Radix Astragali 9-45 heat very the person add Cortex Moutan 10-30 Caulis Lonicerae 10-60 Radix Paeoniae Rubra 6-15 Semen Coicis 6-30 Cortex erythrinae 6-12 Caulis Trachelospermi 6-15 and subtract Radix Aconiti Preparata 3-30
2, the medicine of treatment rheumatoid arthritis according to claim 1, wherein the weight proportion of each raw material is
(a) basic medicament: fleece-flower root 10-15 Radix Codonopsis 10-25 Radix Angelicae Sinensis 10-20 gives birth to the windproof 3-9 bark of ash of Radix Astragali 10-25 sealwort 10-30 bighead atractylodes rhizome 7-12 rhizoma cibotii 4.5-9 scorpio 3-6 earthworm 6-12 zaocys dhumnade 3-9 ant 5-20 red sage root 6-20 ramulus mori 15-60 cassia twig 8-20 rhizoma atractylodis 5-12 notopterygium root 3-9 levisticum 3-10 5-15 parasitic loranthus 10-15 bark of eucommia 10-30 radix cyathulae 6-80 golden cypress 3-10 rhizoma homalonemae 5-12 and bores the sub-9-25 corydalis tuber of ground maple 5-15 frankincense 3-12 myrrh 3-12 caulis sinomenii 9-12 rhizoma arisaematis 3-10 reticulate millettia 15-40 mulberries 5-9 Ligusticum wallichii 3-10 jujube kernel 12-18 wind-weed 6-15 Poria cocos 9-30 aconiti preparata,radix 6-12 HERBA EPIMEDII 8-12 safflower 6-10 Radix Glycyrrhizae 3-10
(b) plus-minus raw material: cold very person add Radix Aconiti Kusnezoffii Preparata 6-12 Radix Dipsaci 9-15 Radix Astragali Mongolici (processed) 10-25 subtract Radix Astragali 10-25 heat very the person add Cortex Moutan 15-25 Caulis Lonicerae 12-30 Radix Paeoniae Rubra 8-15 Semen Coicis 10-30 Cortex erythrinae 8-12 Caulis Trachelospermi 10-15 and subtract Radix Aconiti Preparata 6-12
3, treatment medicine for treating rheumatoid arthritis according to claim 1, wherein the weight proportion of each raw material is
(a) basic medicament: the fleece-flower root 15 Radix Codonopsis 18 Radix Angelicae Sinensis 15 are given birth to the Radix Astragali 20 sealworts 20 bighead atractylodes rhizomes 12 rhizoma cibotii 6 scorpios 6 earthworms 10 zaocys dhumnades 9 ants 12 reds sage root 15 ramulus moris 30 cassia twig 9 rhizoma atractylodis 10 notopterygium roots 9 levisticums 9 windproof 8 bark of ash, 15 parasitic loranthus, 15 barks of eucommia, 20 radix cyathulaes, 15 golden cypresses, 9 rhizoma homalonemaes 10 and are bored ground maple 10 frankincenses 8 myrrhs 8 caulis sinomeniis 10 rhizoma arisaematis 9 reticulate millettias 30 mulberries 12 corydalis tubers 9 Ligusticum wallichiis 10 jujube kernels 16 wind-weeds 10 Poria cocos 15 aconiti preparata,radixs 9 HERBA EPIMEDIIs 10 safflowers 10 Radix Glycyrrhizaes 6
(b) plus-minus raw material: cold very person add Radix Aconiti Kusnezoffii Preparata 9 Radix Dipsacis 12 Radix Astragali Mongolici (processed) 20 subtract Radix Astragali 20 heat very the person add Cortex Moutan 18 Caulis Loniceraes 15 Radix Paeoniae Rubra 10 Semen Coiciss 18 Cortex erythrinaes 10 Caulis Trachelospermis 12 and subtract Radix Aconiti Preparata 9
4,, it is characterized in that said medicament is a said dosage form on any pharmaceutics according to the medicine of claim 1,2 or 3 described treatment rheumatoid arthritiss.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB011177098A CN1169541C (en) | 2001-05-04 | 2001-05-04 | Medicine for treating rheumatoid arthritis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB011177098A CN1169541C (en) | 2001-05-04 | 2001-05-04 | Medicine for treating rheumatoid arthritis |
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| Publication Number | Publication Date |
|---|---|
| CN1327841A true CN1327841A (en) | 2001-12-26 |
| CN1169541C CN1169541C (en) | 2004-10-06 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB011177098A Expired - Fee Related CN1169541C (en) | 2001-05-04 | 2001-05-04 | Medicine for treating rheumatoid arthritis |
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