CN103006979B - Chinese medicinal composition for treating nephrotic edema - Google Patents
Chinese medicinal composition for treating nephrotic edema Download PDFInfo
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- CN103006979B CN103006979B CN201210479232.0A CN201210479232A CN103006979B CN 103006979 B CN103006979 B CN 103006979B CN 201210479232 A CN201210479232 A CN 201210479232A CN 103006979 B CN103006979 B CN 103006979B
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Abstract
The invention relates to a Chinese medicinal composition for treating nephritic edema, which consists of the following Chinese medicinal raw materials in parts by weight: 5 to 15 parts of monkshood, 5 to 15 parts of rhizoma alismatis, 10 to 20 parts of dogwood, 20 to 40 parts of yam, 5 to 15 parts of peony tree root bark, 20 to 40 parts of plantain seed, 10 to 30 parts of prepared rehmannia, 3 to 9 parts of cinnamon, 20 to 40 parts of poria, 10 to 30 parts of motherwort, 10 to 20 parts of twotooth achyranthes root, 10 to 20 parts of red-rooted cassia root, 50 to 70 parts of astragalus, 10 to 20 parts of codonopsis pilosula, 20 to 40 parts of poria, 10 to 30 parts of bighead atractylodes rhizome, and 20 to 40 parts of gorgon euryale seed. The Chinese medicinal composition has the functions of clearing heat and drying dampness, promoting diuresis for stranguria, strengthening spleen and reinforcing kidney, and activating blood to remove stasis, has the advantages of remarkable curative effect and reliable effect in treating nephritic edema, is wide in medicinal component source and easy to prepare, and does not have toxic or side effect.
Description
Technical field
The present invention relates to a kind of medicinal preparation of not determining structure of traditional herbal medicines, especially a kind of oral traditional Chinese medicine composition for the treatment of nephrotic edema.
Background technology
Nephropathy generation edema is because nephropathy patient's urine cannot excrete, and piles up in vivo the edema causing.The pathogenic factor of nephrotic edema has multiple: one, and when after kidney generation pathological changes, two renal blood flow groundwater increments can reduce, excess of the kidney matter ischemia, anoxia, and renin secretion increases; Its two, patient is in suffering from kidney disease, along with the spilling gradually of aggravation albumen of the state of an illness increased, albuminuria long-term existence also increases the weight of the damage of kidney day by day, forms hypoproteinemia, and plasma colloid osmotic pressure is reduced, extracellular fluid is trapped in interstice, causes edema; Its three because the immunity of nephropathy patient's health damages the permeability of the whole body capillary wall causing, cause the moisture in blood plasma to ooze the edema causing to interstice.
The method for the treatment of nephrotic edema has much now, is wherein mainly divided into doctor trained in Western medicine and the traditional Chinese medical science: western medical treatment nephrotic edema is mainly to carry out symptomatic treatment, by the treatment of Western medicine, and alleviate kidney disease edema symptom, but after pastille, there will be recurrence.
Chinese traditional treatment nephrotic edema is contrary with doctor trained in Western medicine, Chinese traditional treatment is to start with from " source of disease ": when nephrotic edema Chinese traditional treatment, answer clearing away heat-damp and promoting diuresis, blood circulation promoting and blood stasis dispelling, in Primary Care (comprise and control blood glucose, treatment hypertension, low-salt high-quality low protein diet), rationally applies Qingrejiedulishi therapy, can eliminate and alleviate damp and hot heresy, suppress the reaction of kidney immune inflammation, for reducing albuminuria, promote the reparation of nephropathy, and then improve renal function, actively control the progress of primary disease.
Summary of the invention
In order to overcome the deficiencies in the prior art, the invention provides a kind ofly prepare conveniently, medicine source is wide, cost is low, the oral traditional Chinese medicine composition of evident in efficacy, reliable effect, the treatment nephrotic edema that has no side effect.
The technical solution adopted for the present invention to solve the technical problems is: a kind of oral traditional Chinese medicine composition for the treatment of nephrotic edema, it is characterized in that: it is to be decocted with water and made by the raw material of Chinese medicine of following weight portion proportioning: Radix Aconiti Lateralis Preparata 5-15 part, Rhizoma Alismatis 5-15 part, Fructus Corni 10-20 part, Rhizoma Dioscoreae 20-40 part, Cortex Moutan 5-15 part, Semen Plantaginis 20-40 part, Radix Rehmanniae Preparata 10-30 part, Cortex Cinnamomi 3-9 part, Poria 20-40 part, Herba Leonuri 10-30 part, Radix Achyranthis Bidentatae 10-20 part, Radix Salviae Miltiorrhizae 10-20 part, Radix Astragali 50-70 part, Radix Codonopsis 10-20 part, Poria 20-40 part, Rhizoma Atractylodis Macrocephalae 10-30 part, Semen Euryales 20-40 part.
The preferred technical solution of the present invention is: a kind of oral traditional Chinese medicine composition for the treatment of nephrotic edema, is characterized in that: it is to be decocted with water and made by the raw material of Chinese medicine of following weight portion proportioning: 10 parts of Radix Aconiti Lateralis Preparatas, 10 parts of Rhizoma Alismatis, 15 parts of Fructus Corni, 30 parts of Rhizoma Dioscoreaes, 10 parts of Cortex Moutans, 30 parts of Semen Plantaginiss, 20 parts, Radix Rehmanniae Preparata, 6 parts of Cortex Cinnamomis, 30 parts, Poria, 20 parts of Herba Leonuris, 15 parts of Radix Achyranthis Bidentataes, 15 parts of Radix Salviae Miltiorrhizaes, 60 parts of the Radixs Astragali, 15 parts of Radix Codonopsis, 30 parts, Poria, 20 parts of the Rhizoma Atractylodis Macrocephalaes, 30 parts of Semen Euryaless.
Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience guidance, selected medicament composing prescription.In Chinese medicine composition of the present invention: Radix Aconiti Lateralis Preparata has recuperating depleted YANG and rescuing the patient from collapse, mends effect fiery supporing yang, dispersing cold for relieving pain; Rhizoma Alismatis has promoting diuresis to eliminate damp pathogen, treating stranguria function expels the heat-evil; Fructus Corni has effect of liver and kidney tonifying, essence astringing and desertion stemming; Rhizoma Dioscoreae has strengthening the spleen and tonifying the lung, stomach reinforcing the kidney invigorating, the benefit of reinforcing the kidney essence, hearing-improing and eyesight improving, help the five internal organs, bone and muscle strengthening, grow that will is calmed the nerves, effect of life lengthening; Cortex Moutan has effect of clearing away heat and cooling blood, promoting blood circulation to remove blood stasis; Effect of Semen Plantaginis relieving stranguria by diuresis, eliminating dampness by diuresis antidiarrheal, liver heat removing and eyesight improving, removing heat-phlegm; Radix Rehmanniae Preparata has effect of the yin nourishing of enriching blood, life essence-filling, marrow-benefitting; Cortex Cinnamomi has the effect of mending supporing yang, the dispersing cold for relieving pain of fire, promoting blood circulation to restore menstrual flow; Poria has effect of promoting diuresis to eliminate damp pathogen, strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming; Herba Leonuri has effect of promoting blood flow to regulate menstruation, blood stasis dispelling diuretic, heat-clearing and toxic substances removing; Radix Achyranthis Bidentatae has effect of eliminating blood stasis and inducing menstruation, easing joint movement, inducing diuresis for treating stranguria syndrome; Radix Salviae Miltiorrhizae has effect of promoting blood flow to regulate menstruation, blood stasis dispelling eliminating carbuncle, the relieving restlessness that clears away heart-fire, nourishing blood to tranquillize the mind; The Radix Astragali has that benefiting QI for strengthening the superficies, tonifying the lung spleen invigorating, arresting sweating are admittedly de-, wind dispelling is transported malicious effect; Radix Codonopsis has effect of invigorating the spleen and replenishing QI, spleen invigorating lung benefiting; Poria has effect of promoting diuresis to eliminate damp pathogen, strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming; The Rhizoma Atractylodis Macrocephalae has invigorating the spleen and benefiting QI, dampness diuretic, the antiabortive effect of hidroschesis; Semen Euryales has the function of supplementing the kidney to control the nocturnal, spleen reinforcing antidiarrheal, damp eliminating leukorrhagia stopping.Drug component in the present composition is through dialectical compatibility, complements each other using, and has synergism, plays altogether effect of heat clearing and damp drying, relieving stranguria by diuresis, spleen benefiting and strengthen kidney, promoting blood circulation to remove blood stasis, nephrotic edema reached to the object for the treatment of both the principal and secondary aspects of a disease.
The component of the present composition all adopts natural raw material of Chinese medicine, and its preparation is easy, medicine source is wide, cost is low.It follows the prescriptions principle of the traditional Chinese medical science, and various component drug adopt the use that is decocted in water for oral dose.Through clinical practice checking, it is evident in efficacy, reliable effect, and the property of medicine is gentle, does not occur toxic and side effects, total effective rate 92.5%, cure rate reaches 62.3%.
Detailed description of the invention
Below in conjunction with embodiment, the present invention will be further described.
Embodiment 1
Treat an oral traditional Chinese medicine composition for nephrotic edema, it is to be decocted with water and made by the raw material of Chinese medicine of following weight proportion: Radix Aconiti Lateralis Preparata 10g, Rhizoma Alismatis 10g, Fructus Corni 15g, Rhizoma Dioscoreae 30g, Cortex Moutan 10g, Semen Plantaginis 30g, Radix Rehmanniae Preparata 20g, Cortex Cinnamomi 6g, Poria 30g, Herba Leonuri 20g, Radix Achyranthis Bidentatae 15g, Radix Salviae Miltiorrhizae 15g, Radix Astragali 60g, Radix Codonopsis 15g, Poria 30g, Rhizoma Atractylodis Macrocephalae 20g, Semen Euryales 30g.
Embodiment 2
Treat an oral traditional Chinese medicine composition for nephrotic edema, it is to be decocted with water and made by the raw material of Chinese medicine of following weight proportion: Radix Aconiti Lateralis Preparata 5g, Rhizoma Alismatis 15g, Fructus Corni 10g, Rhizoma Dioscoreae 40g, Cortex Moutan 5g, Semen Plantaginis 40g, Radix Rehmanniae Preparata 10g, Cortex Cinnamomi 9g, Poria 20g, Herba Leonuri 30g, Radix Achyranthis Bidentatae 10g, Radix Salviae Miltiorrhizae 20g, Radix Astragali 50g, Radix Codonopsis 20g, Poria 20g, Rhizoma Atractylodis Macrocephalae 30g, Semen Euryales 20g.
Embodiment 3
Treat an oral traditional Chinese medicine composition for nephrotic edema, it is to be decocted with water and made by the raw material of Chinese medicine of following weight proportion: Radix Aconiti Lateralis Preparata 15g, Rhizoma Alismatis 5g, Fructus Corni 20g, Rhizoma Dioscoreae 20g, Cortex Moutan 15g, Semen Plantaginis 20g, Radix Rehmanniae Preparata 30g, Cortex Cinnamomi 3g, Poria 40g, Herba Leonuri 10g, Radix Achyranthis Bidentatae 20g, Radix Salviae Miltiorrhizae 10g, Radix Astragali 70g, Radix Codonopsis 10g, Poria 40g, Rhizoma Atractylodis Macrocephalae 10g, Semen Euryales 40g.
Embodiment 4
Treat an oral traditional Chinese medicine composition for nephrotic edema, it is to be decocted with water and made by the raw material of Chinese medicine of following weight proportion: Radix Aconiti Lateralis Preparata 7g, Rhizoma Alismatis 13g, Fructus Corni 12g, Rhizoma Dioscoreae 35g, Cortex Moutan 8g, Semen Plantaginis 35g, Radix Rehmanniae Preparata 15g, Cortex Cinnamomi 8g, Poria 25g, Herba Leonuri 25g, Radix Achyranthis Bidentatae 12g, Radix Salviae Miltiorrhizae 18g, Radix Astragali 55g, Radix Codonopsis 18g, Poria 25g, Rhizoma Atractylodis Macrocephalae 25g, Semen Euryales 25g.
Embodiment 5
Treat an oral traditional Chinese medicine composition for nephrotic edema, it is to be decocted with water and made by the raw material of Chinese medicine of following weight proportion: Radix Aconiti Lateralis Preparata 13g, Rhizoma Alismatis 8g, Fructus Corni 18g, Rhizoma Dioscoreae 25g, Cortex Moutan 13g, Semen Plantaginis 25g, Radix Rehmanniae Preparata 25g, Cortex Cinnamomi 5g, Poria 35g, Herba Leonuri 15g, Radix Achyranthis Bidentatae 18g, Radix Salviae Miltiorrhizae 12g, Radix Astragali 65g, Radix Codonopsis 12g, Poria 35g, Rhizoma Atractylodis Macrocephalae 15g, Semen Euryales 35g.
Chinese medicine composition in embodiment of the present invention decocting method is routinely produced medicament.Concrete grammar is as follows: the raw material of Chinese medicine of prescription is put into container, add cold water and cover powder, soak 15～20 minutes, then add water and do not have approximately 8 centimetres of powder, decoct.At a simmer, adopt intense fire to decoct, after boiling, use slow fire boiling 20～30 minutes; Decoct for the second time, add water and do not have approximately 5 centimetres of powder, after water boils, decoct 15～20 minutes.Twice decoction extracting juice that removes slag, merges.
Treat an oral traditional Chinese medicine composition for nephrotic edema, clinical efficacy is summed up:
One, general data: this Chinese medicine composition is applied to clinical observation case 53 examples, wherein male 26 examples, female's 27 examples, 40～70 years old age.The shortest person of the course of disease 1 month, elder reaches 2 years, average 0.8 year.
Two, diagnostic criteria:
1, edema is first from eyelid or lower limb, continues and extremity, whole body;
2, only eyelid or sufficient shin edema of the lighter, severe one whole body is all swollen, very enlarged abdomen distension, asthma can not be put down sleeping;
3, the visible urine retention of severe patient, nausea and vomiting, mouth has dirty taste, bleeding from the gum epistaxis, very headache, twitches, the crisis such as unconsciousness and delirium;
4, can there be tonsillitis, cardiopalmus, sore, purpura and weakness due to chronic disease history;
5, should make routine urinalysis, twenty-four-hour urine protein quantification, routine blood test, erythrocyte sedimentation rate, plasma albumin, blood urea nitrogen, creatinine, humoral immunization, and electrocardiogram, cardiac determination, the lab testings such as B ultrasonic, clarify a diagnosis to help.
Three, usage and dosage: when clinical practice, component, consumption in compositions are taken the circumstances into consideration increase and decrease according to patient's body weight, age and symptom.Within five days, be a course for the treatment of, one day potion, the about 300ml of twice extracting juice of decocting, point early, late twice half an hour ante cibum warm taking.Period in a medicine avoids eating anything raw or cold, the thing of pungent, stimulation.
Four, criterion of therapeutical effect:
1, cure: edema all disappears, other transference cures, it is normal that lab testing recovers.
2, take a turn for the better: edema and other symptoms alleviate, and lab testing is improved.
3, do not heal: edema and other symptoms and lab testing are unchanged.
Five, therapeutic effect: in this clinical observation case, take medicine 1-5 the course for the treatment of, cure 33 examples, 16 examples that take a turn for the better, 4 examples do not heal.During treatment, there is not toxic and side effects.
Six, model case:
Case 1:
Xiao, man, 67 years old, urine amount was few, xerostomia wish drink, hydrosarca.Red tongue with yellow fur, rolling pulse is strong.Take 2 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, edema disappears.After continuing to take 2 courses for the treatment of, defecation is normal, and thirsty sense alleviates to normally.
Case 2
Ma, female, 61 years old, frequent micturition amount was few, mixed as fat, have a dizzy spell, tinnitus, blurred vision, dry mouth with parched lips, slight edema.Red and uncoated tongue, thready pulse stringy and rapid pulse.Take 2 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, have a dizzy spell, tinnitus disappears, and edema alleviates.After continuing to take 3 courses for the treatment of, edema disappears, and clear depending on thing, also can sleep peacefully night, urine frequency normalization.
Claims (2)
1. an oral traditional Chinese medicine composition for the treatment of nephrotic edema, is characterized in that: it is to be decocted with water and made by the raw material of Chinese medicine of following weight portion proportioning: Radix Aconiti Lateralis Preparata 5-15 part, Rhizoma Alismatis 5-15 part, Fructus Corni 10-20 part, Rhizoma Dioscoreae 20-40 part, Cortex Moutan 5-15 part, Semen Plantaginis 20-40 part, Radix Rehmanniae Preparata 10-30 part, Cortex Cinnamomi 3-9 part, Poria 20-40 part, Herba Leonuri 10-30 part, Radix Achyranthis Bidentatae 10-20 part, Radix Salviae Miltiorrhizae 10-20 part, Radix Astragali 50-70 part, Radix Codonopsis 10-20 part, Poria 20-40 part, Rhizoma Atractylodis Macrocephalae 10-30 part, Semen Euryales 20-40 part.
2. a kind of interior Chinese medicine composition for the treatment of nephrotic edema according to claim 1, is characterized in that: it is to be decocted with water and made by the raw material of Chinese medicine of following weight portion proportioning: 10 parts of Radix Aconiti Lateralis Preparatas, 10 parts of Rhizoma Alismatis, 15 parts of Fructus Corni, 30 parts of Rhizoma Dioscoreaes, 10 parts of Cortex Moutans, 30 parts of Semen Plantaginiss, 20 parts, Radix Rehmanniae Preparata, 6 parts of Cortex Cinnamomis, 30 parts, Poria, 20 parts of Herba Leonuris, 15 parts of Radix Achyranthis Bidentataes, 15 parts of Radix Salviae Miltiorrhizaes, 60 parts of the Radixs Astragali, 15 parts of Radix Codonopsis, 30 parts, Poria, 20 parts of the Rhizoma Atractylodis Macrocephalaes, 30 parts of Semen Euryaless.
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| CN201210479232.0A CN103006979B (en) | 2012-11-23 | 2012-11-23 | Chinese medicinal composition for treating nephrotic edema |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103211952B (en) * | 2013-05-20 | 2014-05-28 | 广州市云桥生物科技有限公司 | Traditional Chinese medicine composition used for treating edema |
| CN103623334A (en) * | 2013-12-12 | 2014-03-12 | 王芬 | Traditional Chinese medicine composition for treating nephritis |
| CN104857365A (en) * | 2015-04-27 | 2015-08-26 | 青岛市市立医院 | Drug combination for curing senile macular oedema |
| CN106474385A (en) * | 2016-11-07 | 2017-03-08 | 陈中元 | A kind of medicine treating swollen disease |
| CN110101808A (en) * | 2019-06-13 | 2019-08-09 | 郭涤尘 | It is a kind of to treat uremic Chinese medicinal capsule |
| CN111012875A (en) * | 2019-12-26 | 2020-04-17 | 吴育文 | Chinese medicinal preparation for treating acute and chronic nephritis |
| CN113813299A (en) * | 2021-09-28 | 2021-12-21 | 郭俊卿 | Traditional Chinese medicine formula for treating nephropathy and preparation method thereof |
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| CN1544015A (en) * | 2003-11-21 | 2004-11-10 | 金良田 | Kidney failure resistant formula and its preparation process |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1544015A (en) * | 2003-11-21 | 2004-11-10 | 金良田 | Kidney failure resistant formula and its preparation process |
| CN101095794A (en) * | 2007-07-05 | 2008-01-02 | 北京艺信堂医药研究所 | Chinese traditional medicine preparations for treating drug-induced nephritis |
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