CN104435545A - Traditional Chinese medicine preparation for treating leucopenia caused by benzene poisoning - Google Patents

Traditional Chinese medicine preparation for treating leucopenia caused by benzene poisoning Download PDF

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CN104435545A
CN104435545A CN201410665421.6A CN201410665421A CN104435545A CN 104435545 A CN104435545 A CN 104435545A CN 201410665421 A CN201410665421 A CN 201410665421A CN 104435545 A CN104435545 A CN 104435545A
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chinese medicine
leukopenia
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CN104435545B (en
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孙银贵
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Weifang Medical University
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/894Dioscoreaceae (Yam family)
    • A61K36/8945Dioscorea, e.g. yam, Chinese yam or water yam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11Pteridophyta or Filicophyta (ferns)
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286Carthamus (distaff thistle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/486Millettia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/487Psoralea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537Salvia (sage)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/74Rubiaceae (Madder family)
    • A61K36/746Morinda
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/19Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment

Abstract

The invention relates to a traditional Chinese medicine preparation for treating leucopenia caused by benzene poisoning. The preparation is prepared from astragalus membranaceus, angelica sinensis, radix ginseng rubra, pericarpium citri reticulatae, rhizoma atractylodis macrocephalae, dried radix rehmanniae, Chinese yam, salvia miltiorrhiza, spatholobus suberctu, radix morindae officinalis, scorch-fried medicated leaven, safflower, herba pyrrosiae, polygonum cuspidatum, cortex lycii radicis and fructus psoraleae. The preparation has the effects of nourishing vitality, nourishing blood and yin, lowering internal fire, warming yang, tonifying qi, replenishing blood, tranquilizing and the like. By taking the traditional Chinese medicine preparation, the immunity of users can be improved, infection can be controlled, hypersplenism can be inhibited, and hemopoietic growth factors can be increased, so that neutrophils can be increased, the functions of the neutrophils in phagocytosis, sterilization and chemotaxis can be reinforced, leukocytes can be recovered to normal, and the percentage of lymphocyte can be promoted to be relatively reduced. By means of comprehensive treatment, headache, low fever, weakness, general malaise, pharyngeal infection and other symptoms caused by leukopenia can be completely eliminated, balances of cells can be finally achieved, endocrine disorder can be regulated, and benzene poisoning caused leukopenia can be completely cured.

Description

A kind of Chinese medicine preparation for the treatment of caused by benzene leukopenia
Technical field
The invention belongs to the field of Chinese medicines, specifically a kind of Chinese medicine preparation can treating caused by benzene leukopenia.
Background technology
Leukopenia refers to that peripheral blood leucocyte absolute counting continues lower than 4.0 × 10^9 (9 power)/L.Neutrophilic granulocyte is leukocytic main component, so Neutrophilic granulocytopenia often causes leukopenia.Benzolism is a kind of chronic occupational leukopenia, and main cause works in containing the environment of benzene for a long time to cause.Primary disease can be divided into slightly according to the degree of Neutrophilic granulocytopenia, moderate, severe leukopenia.Most patients onset is slow, the patient clinical of general slight minimizing does not occur characteristic symptom, shows as protopathy symptom more.Moderate and severe minimizing person easily occur to infect and occur the nonspecific symptoms such as tired, unable, dizzy, loss of appetite, pharyngolaryngitis and mucosa ulcer.
At present, doctor trained in Western medicine many employings batilol, leucogen, the auspicious Drug therapy such as in vain, but weak curative effect, side effect is large; And the traditional Chinese medical science thinks that caused by benzene leukopenia is primarily cause QI and blood deficiency, spleen kidney deficiency, deficiency of kidney-QI, then insufficiency of essence, marrow is discontented with, then hemopoietic is passive, and deficiency of spleen-QI then transporting is unable, blood and essence asthenia.Nourishing the liver and kidney, replenishing QI and blood are Therapeutic Principle by the traditional Chinese medical science, combine, and strengthen the immunity of human body, therefore are one of effective methods from the angle treatment caused by benzene leukopenia of the traditional Chinese medical science.
Summary of the invention
The problem to be solved in the present invention is for above problem, provides the Chinese medicine preparation of the treatment caused by benzene leukopenia that a kind of cure rate is high, side effect is little, relapse rate is low.
For solving the problem, the technical solution adopted in the present invention is:
Treat a Chinese medicine preparation for caused by benzene leukopenia, it is characterized in that, described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Radix Astragali 20-30 gram, Radix Angelicae Sinensis 10-20 gram, Radix Ginseng Rubra 10-20 gram, Pericarpium Citri Reticulatae 10-20 gram, Rhizoma Atractylodis Macrocephalae 10-20 gram, Radix Rehmanniae 10-20 gram, Rhizoma Dioscoreae 10-20 gram, Radix Salviae Miltiorrhizae 10-20 gram, Caulis Spatholobi 10-20 gram, bar halberd 8-15 gram, burnt six bent 8-12 grams, Flos Carthami 8-12 gram, Folium Pyrrosiae 8-12 gram, Rhizoma Polygoni Cuspidati 8-12 gram, Cortex Lycii 8-12 gram, Fructus Psoraleae 8-15 gram.
As a kind of prioritization scheme:
Described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
The Radix Astragali 20 grams, Radix Angelicae Sinensis 10 grams, Radix Ginseng Rubra 10 grams, Pericarpium Citri Reticulatae 10 grams, the Rhizoma Atractylodis Macrocephalae 10 grams, 10 grams, the Radix Rehmanniae, Rhizoma Dioscoreae 10 grams, Radix Salviae Miltiorrhizae 10 grams, Caulis Spatholobi 10 grams, bar halberd 8 grams, burnt six songs 8 grams, Flos Carthami 8 grams, Folium Pyrrosiae 8 grams, Rhizoma Polygoni Cuspidati 8 grams, Cortex Lycii 8 grams, Fructus Psoraleae 8 grams.
As a kind of prioritization scheme:
Described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
The Radix Astragali 30 grams, Radix Angelicae Sinensis 20 grams, Radix Ginseng Rubra 20 grams, Pericarpium Citri Reticulatae 20 grams, the Rhizoma Atractylodis Macrocephalae 20 grams, 20 grams, the Radix Rehmanniae, Rhizoma Dioscoreae 20 grams, Radix Salviae Miltiorrhizae 20 grams, Caulis Spatholobi 20 grams, bar halberd 15 grams, burnt six songs 12 grams, Flos Carthami 12 grams, Folium Pyrrosiae 12 grams, Rhizoma Polygoni Cuspidati 12 grams, Cortex Lycii 12 grams, Fructus Psoraleae 15 grams.
As a kind of prioritization scheme:
Described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
The Radix Astragali 25 grams, Radix Angelicae Sinensis 15 grams, Radix Ginseng Rubra 15 grams, Pericarpium Citri Reticulatae 15 grams, the Rhizoma Atractylodis Macrocephalae 15 grams, 15 grams, the Radix Rehmanniae, Rhizoma Dioscoreae 15 grams, Radix Salviae Miltiorrhizae 15 grams, Caulis Spatholobi 15 grams, bar halberd 12 grams, burnt six songs 10 grams, Flos Carthami 10 grams, Folium Pyrrosiae 10 grams, Rhizoma Polygoni Cuspidati 10 grams, Cortex Lycii 10 grams, Fructus Psoraleae 12 grams.
Wherein:
Radix Astragali sweet in the mouth, slightly warm in nature, returns spleen, lung meridian, has QI invigorating, yang invigorating, benefit defend consolidating superficial resistance, detoxification, granulation promoting, diuretic, subsides a swelling, nourishes blood, the effect such as mind calming, YIN nourishing, pathogenic fire reducing.
Radix Angelicae Sinensis bitter in the mouth, warm in nature, return liver, the heart, spleen channel, have nourish blood, enrich blood, QI invigorating, warming YANG, QI invigorating, regulating menstruation, the effect such as YIN nourishing.
Radix Ginseng Rubra mildly bitter flavor, warm in nature, return spleen, lung, heart channel, there is QI invigorating, QI invigorating, nourish blood, enrich blood, admittedly take off, promote the production of body fluid, the effect such as warming YANG, YIN nourishing.
Pericarpium Citri Reticulatae bitter in the mouth, warm in nature, return spleen, stomach, lung meridian, there is warming YANG, regulate the flow of vital energy, QI invigorating, foster the spirit of nobility, invigorate blood circulation, nourish blood, the effect such as YIN nourishing, pathogenic fire reducing.
Rhizoma Atractylodis Macrocephalae bitter in the mouth, warm in nature, return spleen, stomach warp, there is spleen invigorating, QI invigorating, enrich blood, the effect such as YIN nourishing, warming YANG.
Radix Rehmanniae bitter in the mouth, cold in nature, GUIXIN, liver, kidney channel, there is YIN nourishing, enrich blood, the kidney invigorating, regulating menstruation, yin nourishing, the effect such as to promote the production of body fluid.
Rhizoma Dioscoreae sweet in the mouth, warm in nature, return spleen, lung, kidney channel, there is QI invigorating, QI invigorating, invigorate blood circulation, nourish blood, YIN nourishing, promote the production of body fluid, the effect such as mind calming, pathogenic fire reducing.
Radix Salviae Miltiorrhizae bitter in the mouth, cold nature, GUIXIN, Liver Channel, have invigorate blood circulation, nourish blood, calm the nerves, mind calming, clear away heart-fire, the effect such as YIN nourishing, pathogenic fire reducing.
Caulis Spatholobi sweet in the mouth, warm in nature, return liver, kidney channel, have enrich blood, nourish blood, the effect such as dredging collateral, YIN nourishing, pathogenic fire reducing.Find that Caulis Spatholobi has very large effect to hemopoietic system after deliberation.
Bar halberd bitter in the mouth, slightly warm in nature, returns kidney channel, the effect such as have warming YANG, pathogenic fire reducing, YIN nourishing, QI invigorating, QI invigorating, nourish blood.
Burnt six bent sweet in the mouth, warm in nature, return spleen, stomach warp, the effect such as there is QI invigorating, warming YANG, dredging collateral, YIN nourishing, nourish blood.
Flos Carthami and Flos Carthami, bitter in the mouth, warm in nature, GUIXIN, Liver Channel, have QI invigorating, nourish blood, invigorate blood circulation, enrich blood, the effect such as YIN nourishing, warming YANG, mind calming.
Folium Pyrrosiae mildly bitter flavor, cool in nature, return lung, bladder, small intestine meridian, there is QI invigorating, dredging collateral, QI invigorating, enrich blood, invigorate blood circulation, the effect such as warming YANG.
Rhizoma Polygoni Cuspidati mildly bitter flavor, cold nature, returns liver, gallbladder, lung meridian, have enrich blood, QI invigorating, pathogenic fire reducing, YIN nourishing, warming YANG, the effect such as to invigorate blood circulation.
Cortex Lycii sweet in the mouth, cold nature, returns lung, liver, kidney channel, have nourish blood, pathogenic fire reducing, warming YANG, QI invigorating, the effect such as calmness.
Fructus Psoraleae bitter in the mouth, warm in nature, return kidney, spleen channel, there is warming YANG, QI invigorating, pathogenic fire reducing, YIN nourishing, enrich blood, the effect such as mind calming, QI invigorating.
Between every taste Chinese medicine in the present invention, by drawing after several clinical formulation, its manufacture method is simple, the dosage forms such as tablet, pill, powder or oral liquid can be made into as required, Chinese medicine preparation of the present invention has QI invigorating, nourishes blood, YIN nourishing, pathogenic fire reducing, warming YANG, QI invigorating, enrich blood, the effect such as mind calming.Take the immunity that can improve self, infection control, suppress hypersplenism, improve hemopoietic growth factor, neutrophilic granulocyte is increased, and strengthen its Phagocytosis and Chemotaxis Function, leukocyte can recover normal with this, lymphocyte percentage is impelled relatively to reduce, by Comprehensive Treatment, thoroughly can remove the symptoms such as the headache because leukopenia brings, low grade fever, weak, general malaise, pharyngeal infection, finally reach the balance of each cell, adjust endocrine disorder, realize the thorough healing to caused by benzene leukopenia.
Manufacture method of the present invention:
After being mixed by weight by above-mentioned Chinese medicine, add decocting to hour, filtering medicinal residues, obtain oral liquid.Be ground into end after above-mentioned Chinese medicine can mix by tablet, powder, pill or capsule by weight as made, make tablet, powder, pill or capsule.
Instructions of taking: every day potion, every day three times, one after each meal ten days is a course for the treatment of.
The present invention is according to the pharmacology of above-mentioned Chinese medicine, and clinical trial for several times, to blue or green, in, old Different age group light, in, severe caused by benzene leukopenia patient all has obvious therapeutic effect.
For investigating clinical efficacy and the safety of medicine of the present invention further, we have selected the treatment curative effect of 78 routine caused by benzene leukopenia patients to medicine of the present invention and carry out clinical trial.Wherein, male 38 example, women 40 example, age reckling 18 years old, the oldest person 65 years old, 43.5 years old mean age, the course of disease 6 months to 4 years.
All cases are all diagnosed with reference to the diagnostic criteria of leukopenia in " internal medicine ".
Criterion of therapeutical effect:
Cure: body constitution, sign recover normal, wbc value recovery normally or before comparatively treating is enhanced about more than once;
Effective: body constitution, sign recover normal, leukocyte improves 0.5 × 10^9 (9 power)/more than L before comparatively treating;
Effective: body constitution is normal, often with diseases such as low grade fever, weak, cardiopalmus, leukocyte improves 0.5 × 10^9 (9 power)/below L before comparatively treating;
Invalid: quantity of leucocyte is comparatively treated front unchanged;
78 routine patient treatment outcome are: healing person 48 example (61.5%), effective person 21 example (26.9%), responder 7 example (9.0%), nonresponder 2 example (2.6%), total effective rate 97.4%.
Can find out that Chinese medicine preparation cost of the present invention is low by above-mentioned data, therapeutic effect is remarkable, and takes compared with Western medicine, and cure rate is high, rapid-action, side effect is little, short treating period.
Detailed description of the invention
Embodiment 1: a kind of Chinese medicine preparation for the treatment of caused by benzene leukopenia, described Chinese medicine preparation is made up of the Radix Astragali 20 grams, Radix Angelicae Sinensis 10 grams, Radix Ginseng Rubra 10 grams, Pericarpium Citri Reticulatae 10 grams, the Rhizoma Atractylodis Macrocephalae 10 grams, 10 grams, the Radix Rehmanniae, Rhizoma Dioscoreae 10 grams, Radix Salviae Miltiorrhizae 10 grams, Caulis Spatholobi 10 grams, bar halberd 8 grams, burnt six songs 8 grams, Flos Carthami 8 grams, Folium Pyrrosiae 8 grams, Rhizoma Polygoni Cuspidati 8 grams, Cortex Lycii 8 grams, Fructus Psoraleae 8 grams.
After above-mentioned Chinese herb mixing, decoct with water one hour, elimination medicinal residues, just water decoction for oral use, every day potion, every day three times, one after each meal, it within ten days, is a course for the treatment of, two to four courses for the treatment of just can fully recover, and certainly can carry out suitable interpolation or minimizing according to symptom or age to dose, and follow the doctor's advice, taking period avoids pungent, avoids and flares up.
Embodiment 2: a kind of Chinese medicine preparation for the treatment of caused by benzene leukopenia, described Chinese medicine preparation is made up of the Radix Astragali 30 grams, Radix Angelicae Sinensis 20 grams, Radix Ginseng Rubra 20 grams, Pericarpium Citri Reticulatae 20 grams, the Rhizoma Atractylodis Macrocephalae 20 grams, 20 grams, the Radix Rehmanniae, Rhizoma Dioscoreae 20 grams, Radix Salviae Miltiorrhizae 20 grams, Caulis Spatholobi 20 grams, bar halberd 15 grams, burnt six songs 12 grams, Flos Carthami 12 grams, Folium Pyrrosiae 12 grams, Rhizoma Polygoni Cuspidati 12 grams, Cortex Lycii 12 grams, Fructus Psoraleae 15 grams.
After above-mentioned Chinese herb mixing, decoct with water one hour, elimination medicinal residues, just water decoction for oral use, every day potion, every day three times, one after each meal, it within ten days, is a course for the treatment of, two to four courses for the treatment of just can fully recover, and certainly can carry out suitable interpolation or minimizing according to symptom or age to dose, and follow the doctor's advice, taking period avoids pungent, avoids and flares up.
Embodiment 3: a kind of Chinese medicine preparation for the treatment of caused by benzene leukopenia, described Chinese medicine preparation is made up of the Radix Astragali 25 grams, Radix Angelicae Sinensis 15 grams, Radix Ginseng Rubra 15 grams, Pericarpium Citri Reticulatae 15 grams, the Rhizoma Atractylodis Macrocephalae 15 grams, 15 grams, the Radix Rehmanniae, Rhizoma Dioscoreae 15 grams, Radix Salviae Miltiorrhizae 15 grams, Caulis Spatholobi 15 grams, bar halberd 12 grams, burnt six songs 10 grams, Flos Carthami 10 grams, Folium Pyrrosiae 10 grams, Rhizoma Polygoni Cuspidati 10 grams, Cortex Lycii 10 grams, Fructus Psoraleae 12 grams.
After above-mentioned Chinese herb mixing, decoct with water one hour, elimination medicinal residues, just water decoction for oral use, every day potion, every day three times, one after each meal, it within ten days, is a course for the treatment of, two to four courses for the treatment of just can fully recover, and certainly can carry out suitable interpolation or minimizing according to symptom or age to dose, and follow the doctor's advice, taking period avoids pungent, avoids and flares up.
Some patients healing case is as follows:
Zhu XX, man, 28 years old, just to company's working half a year of a chemical classes, has had a hunch and has felt run-down, uncomfortable, dizzy etc., originally thinks it is flu, does not get better for a long time, through examination in hospital routine blood test; Leukocyte fluctuates in 2.15-3.95, erythrocyte fluctuates in 2.77-3.51, hemoglobin fluctuates in 89-111, neutrophilic granulocyte absolute value fluctuates in 0.58-2.3, and finds in body and have a large amount of benzene, is diagnosed as caused by benzene leukopenia, after taking a course for the treatment of of Chinese medicine preparation of the present invention, sign, body constitution are clearly better, and after continuing to take a course for the treatment of, quantity of leucocyte returns to standard level, recovery from illness.
Zhao XX, female, 45 years old, printing house's working for many years, long-term and benzene was come into contacts with.Had a medical check-up before half a year, finding leukocyte is 3.66, and hospital has opened some Western medicine, and effect is little, after taking a course for the treatment of of Chinese medicine preparation of the present invention, symptom obviously alleviates, and leukocytic quantity obviously rises, after continuing to take two courses for the treatment of, quantity of leucocyte returns to standard level, recovery from illness.
Try to gain XX, female, 52 years old, the working environment at place is throughout the year containing benzene, in recent years, always feel dizzy, weak, the discomfort such as loss of appetite, pharyngolaryngitis is also always controlled bad, have a medical check-up last month and find, quantity of leucocyte is starkly lower than standard level, and take the medicine injected month, symptom is without change, after taking two courses for the treatment of of Chinese medicine preparation of the present invention, symptom obviously alleviates, and quantity of leucocyte increases to some extent, after continuing to take two courses for the treatment of, quantity of leucocyte returns to standard level, and sign, body constitution recover normal.

Claims (4)

1. treat a Chinese medicine preparation for caused by benzene leukopenia, it is characterized in that, described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Radix Astragali 20-30 gram, Radix Angelicae Sinensis 10-20 gram, Radix Ginseng Rubra 10-20 gram, Pericarpium Citri Reticulatae 10-20 gram, Rhizoma Atractylodis Macrocephalae 10-20 gram, Radix Rehmanniae 10-20 gram, Rhizoma Dioscoreae 10-20 gram, Radix Salviae Miltiorrhizae 10-20 gram, Caulis Spatholobi 10-20 gram, bar halberd 8-15 gram, burnt six bent 8-12 grams, Flos Carthami 8-12 gram, Folium Pyrrosiae 8-12 gram, Rhizoma Polygoni Cuspidati 8-12 gram, Cortex Lycii 8-12 gram, Fructus Psoraleae 8-15 gram.
2. a kind of Chinese medicine preparation for the treatment of caused by benzene leukopenia according to claim 1, is characterized in that: described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
The Radix Astragali 20 grams, Radix Angelicae Sinensis 10 grams, Radix Ginseng Rubra 10 grams, Pericarpium Citri Reticulatae 10 grams, the Rhizoma Atractylodis Macrocephalae 10 grams, 10 grams, the Radix Rehmanniae, Rhizoma Dioscoreae 10 grams, Radix Salviae Miltiorrhizae 10 grams, Caulis Spatholobi 10 grams, bar halberd 8 grams, burnt six songs 8 grams, Flos Carthami 8 grams, Folium Pyrrosiae 8 grams, Rhizoma Polygoni Cuspidati 8 grams, Cortex Lycii 8 grams, Fructus Psoraleae 8 grams.
3. a kind of Chinese medicine preparation for the treatment of caused by benzene leukopenia according to claim 1, is characterized in that: described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
The Radix Astragali 30 grams, Radix Angelicae Sinensis 20 grams, Radix Ginseng Rubra 20 grams, Pericarpium Citri Reticulatae 20 grams, the Rhizoma Atractylodis Macrocephalae 20 grams, 20 grams, the Radix Rehmanniae, Rhizoma Dioscoreae 20 grams, Radix Salviae Miltiorrhizae 20 grams, Caulis Spatholobi 20 grams, bar halberd 15 grams, burnt six songs 12 grams, Flos Carthami 12 grams, Folium Pyrrosiae 12 grams, Rhizoma Polygoni Cuspidati 12 grams, Cortex Lycii 12 grams, Fructus Psoraleae 15 grams.
4. a kind of Chinese medicine preparation for the treatment of caused by benzene leukopenia according to claim 1, is characterized in that: described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
The Radix Astragali 25 grams, Radix Angelicae Sinensis 15 grams, Radix Ginseng Rubra 15 grams, Pericarpium Citri Reticulatae 15 grams, the Rhizoma Atractylodis Macrocephalae 15 grams, 15 grams, the Radix Rehmanniae, Rhizoma Dioscoreae 15 grams, Radix Salviae Miltiorrhizae 15 grams, Caulis Spatholobi 15 grams, bar halberd 12 grams, burnt six songs 10 grams, Flos Carthami 10 grams, Folium Pyrrosiae 10 grams, Rhizoma Polygoni Cuspidati 10 grams, Cortex Lycii 10 grams, Fructus Psoraleae 12 grams.
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CN105535463A (en) * 2016-01-18 2016-05-04 陈云 Traditional Chinese medicine composition for treating anemia caused by benzene poisoning
CN105641416A (en) * 2016-01-18 2016-06-08 陈云 Traditional Chinese medicine composition for treating leucopenia caused by benzene poisoning

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105535463A (en) * 2016-01-18 2016-05-04 陈云 Traditional Chinese medicine composition for treating anemia caused by benzene poisoning
CN105641416A (en) * 2016-01-18 2016-06-08 陈云 Traditional Chinese medicine composition for treating leucopenia caused by benzene poisoning

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Inventor after: Sun Yingui

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