CN104491586A - Wind-damp clearing medicinal liquor for rheumatic arthritis and preparation of medicinal liquor - Google Patents

Wind-damp clearing medicinal liquor for rheumatic arthritis and preparation of medicinal liquor Download PDF

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CN104491586A
CN104491586A CN201510003786.7A CN201510003786A CN104491586A CN 104491586 A CN104491586 A CN 104491586A CN 201510003786 A CN201510003786 A CN 201510003786A CN 104491586 A CN104491586 A CN 104491586A
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herba
rheumatic arthritis
bile
expelling wind
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王国徽
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Abstract

The invention discloses wind-damp clearing medicinal liquor for rheumatic arthritis and a preparation method of the medicinal liquor. The medicinal liquor is prepared from the following main medicinal raw materials in parts by weight: 20-40 parts of roots of kudzu vines, 10-20 parts of ligusticum wallichii, 9-12 parts of laciniate begonia herb, 9-15 parts of euonymus bungeanus, 10-16 parts of coix lachryma-jobi kernels, 9-18 parts of dipsacus roots, 9-16 parts of cassia twigs, 8-15 parts of rhizoma arisaematis (processed with bile), 10-20 parts of burdocks, 8-12 parts of melastoma dodecandrum, 10-15 parts of calanthe discolor lindl, 15-30 parts of spina date seeds (fried) and 9-16 parts of cirrhopetalum. The wind-damp clearing medicinal liquor for rheumatic arthritis disclosed by the invention is low in treatment cost, free of side effects and traumas and remarkable in curative effect, and rheumatic arthritis hardly relapses.

Description

Rheumatic arthritis expelling wind and dampness medicated wine and preparation
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of rheumatic arthritis expelling wind and dampness medicated wine and preparation.
Background technology
Rheumatic arthritis is the performance of rheumatic fever in joint, and its classical symptom is migrans, multiple large arthritis.Clinical manifestation: 1. pain.Arthralgia is the modal symptom of rheumatism, and general joint all likely pain occurs, but the pain of limbs and metastomium and internal organs and neural pathological changes may be caused.2. myalgia.Muscle also there will be pain symptom, but also may occur the rising of myasthenia, creatase, Myopathic lesion etc., as systemic lupus erythematosus (sle), mixed connective tissue disease, dermatomyositis etc.3. erratic behavior heating.Rheumatism there will be irregular fever phenomenon before occurring, there will not be phenomenon of shivering, invalid with antibiotic therapy, also there will be erythrocyte sedimentation rate fast, as systemic lupus erythematosus (sle), acute neutrophilia heat generation skin disease, be grown up this Supreme Being you disease, panniculitis etc. all can generate heat for onset symptoms simultaneously.4. skin mucosa symptom.Dermatomyositis, dry syndrome, Behcet disease, panniculitis etc. there will be erythra, oral ulcer, skin ulcer, netted livid purple, eye symptom etc.5. raynaud's sign.Finger tip can turn white when can meet cold or emotion changes, is then transformed into purple, is finally transformed into redness and with numbness, pain and serious skin ulcer, is found in rheumatoid arthritis, systemic lupus erythematosus (sle), mixed connective tissue disease.6. autoantibody physiochemical indice is abnormal.Anti-ENA antibody, anti-ds-DNA antibody, antiplatelet antibody, antinuclear antibody, anticardiolipin antibody, rheumatoid factor etc.
Application publication number CN 102139027 A(application number 201110088955.3) Chinese patent literature disclose a kind of medicated wine for the treatment of rheumatic arthritis, it is by the medicated wine of the herbal medicine immersions such as low alcohol white spirit and Radix Glycyrrhizae, Cortex Acanthopancis, Fructus Chaenomelis, Herba Siegesbeckiae, Rhizoma Homalomenae, Radix Notoginseng, Radix Ginseng.Application publication number CN 103845612 A(application number 201210510176.2) Chinese patent literature disclose one and treat rheumatic arthritis medicated wine, featherleaf rodgersflower 10 ~ 15 grams, Herba Lysionoti Pauciflori 20 ~ 25 grams, 10 ~ 15 grams, Fructus Piperis, Herba pteridis vittatae 40 ~ 45 grams, Quartz Album 40 ~ 45 grams, thousand short 30 ~ 35 grams.Application publication number CN 103690893 A(application number 201310715632.1) Chinese patent literature disclose a kind of medicated wine for the treatment of rheumatic arthritis, it is characterized in that: be made up of following raw material of Chinese medicine, raw material of Chinese medicine is by following parts by weight: Fructus Lycii 25-35 gram, Rhizoma Polygonati 25-35 gram, Rhizoma Atractylodis Macrocephalae 25-35 gram, Radix Aconiti Preparata 25-35 gram, RADIX ACONITILATERALIS PREPARATA 25-35 gram, Rhizoma Et Radix Notopterygii 15-20 gram, Radix Angelicae Pubescentis 15-20 gram, Radix Clematidis 15-20 gram, Radix Angelicae Sinensis 15-20 gram, Rhizoma Curcumae Longae 15-20 gram, Scolopendra 15-20 gram, Zaocys 85-95 gram, Rhizoma Homalomenae 50-60 gram.
Rheumatoid arthritis patients usually torment by arthralgia, and, also because arthralgia makes quality of life decline.Doctor trained in Western medicine mainly adopts analgesia anti-inflammation medicine, amcinonide etc. to control symptom, stablizes the state of an illness, but the most side effect of medicine used is serious, and many patients are inspired awe even from distance.Up to now, the process that a kind of specific medicament can prevent or the articulation structure that significantly slows down destroys is not found.And operative treatment, the features such as because indication requires very strict, the crowd being applicable to clinically performing an operation less than 5%, and exists costly, and wound is large, and convalescent period is long, easy recurrence, so cannot popularize the Therapeutic Method of this rheumatic arthritis in an all-round way at all.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide a kind of rheumatic arthritis expelling wind and dampness medicated wine and preparation method thereof.Rheumatic arthritis expelling wind and dampness medicated wine treatment cost provided by the invention is low, have no side effect, hurtless measure, evident in efficacy, not easily recur.
Technical scheme of the present invention is:
Rheumatic arthritis expelling wind and dampness medicated wine, takes off the primary raw material medicine stating weight proportion and is prepared from: Radix Puerariae 20-40, Rhizoma Chuanxiong 10-20, Herba Begoniae Laciniatae 9-12, Herba Euonymi Bungeani 9-15, Semen Coicis 10-16, Radix Dipsaci 9-18, Ramulus Cinnamomi 9-16, Rhizoma Arisaematis (bile system) 8-15, Fructus Arctii 10-20, Herba Melastomatis Dodecandri 8-12, Herba seu Radix Calanthes 10-15, Semen Ziziphi Spinosae (stir-fry) 15-30, Herba Cirrohopetali Andersonii 9-16.
Rheumatic arthritis expelling wind and dampness medicated wine, preferred scheme is, takes off the primary raw material medicine stating weight proportion and is prepared from: take off the primary raw material medicine stating weight proportion and be prepared from: Radix Puerariae 25-35, Rhizoma Chuanxiong 12-16, Herba Begoniae Laciniatae 10-11, Herba Euonymi Bungeani 11-13, Semen Coicis 12-15, Radix Dipsaci 12-15, Ramulus Cinnamomi 11-14, Rhizoma Arisaematis (bile system) 11-14, Fructus Arctii 13-16, Herba Melastomatis Dodecandri 9-11, Herba seu Radix Calanthes 12-14, Semen Ziziphi Spinosae (stir-fry) 19-24, Herba Cirrohopetali Andersonii 11-14.
Rheumatic arthritis expelling wind and dampness medicated wine, the scheme be more preferably is, takes off the primary raw material medicine stating weight proportion and is prepared from: take off the primary raw material medicine stating weight proportion and be prepared from: Radix Puerariae 32, Rhizoma Chuanxiong 14, Herba Begoniae Laciniatae 10.5, Herba Euonymi Bungeani 12, Semen Coicis 13, Radix Dipsaci 14, Ramulus Cinnamomi 12, Rhizoma Arisaematis (bile system) 12, Fructus Arctii 15, Herba Melastomatis Dodecandri 10, Herba seu Radix Calanthes 13, Semen Ziziphi Spinosae (stir-fry) 22, Herba Cirrohopetali Andersonii 12.
The preparation method of above-mentioned rheumatic arthritis expelling wind and dampness medicated wine is:
(1) by Arisaema Cum Bile levigation, put into cylinder, add bile, every 100kg Rhizoma Arisaematis adds bile 280-450kg, wets as degree, weather exposure to mixing, and to being degree without bad smell, not faling apart, drying, be ground into fine powder so that hand rubbing is agglomerating;
(2) get Semen Coicis rice water and mix leaching, every 100kg Semen Coicis rice water 32-47kg, to inhale profit for degree, even medicine and rice water together enter fried dry in pot, are ground into fine powder;
(3) get clean Semen Ziziphi Spinosae, put in pot to fry with slow fire and to heave to crust and be micro-yellow, taking-up, cools, is ground into fine powder;
(4) all the other the 10 taste medical materials except Rhizoma Arisaematis, Semen Coicis and Semen Ziziphi Spinosae are ground into end;
(5) step (1), step (2), step (3) and step (4) gained are mixed, enter cloth bag, put in tank, add Chinese liquor, the amount of Chinese liquor is 10-16 times of 13 taste Chinese crude drug gross weights, and the number of degrees of Chinese liquor are 50-68 degree, is placed on the sealing of sombre lucifuge place and soaks, every day stirs once, soak 20-30 days, filter medicinal residues, wine liquid leaves standstill 6-12 hour, filter, the wine liquid after filtration is stored in bottle.
Preferably be that, in step (1), the bile added is Fel Bovis seu Bubali, Fel Sus domestica or sheep bile.
Preferably be that, in step (1), every 100kg Rhizoma Arisaematis adds bile 300-400kg.
Preferably be in step (2), every 100kg Semen Coicis rice water 35-43kg.
Preferably be in step (5), the amount of Chinese liquor is 12-15 times of 13 taste Chinese crude drug gross weights.
Preferably be in step (5), the number of degrees of Chinese liquor are 52-60 degree.
Preferably be in step (5), soak 22-28 days.
Preferably be that in step (5), wine liquid leaves standstill 8-11 hour.
Be more preferably, the bile added in step (1) is Fel Bovis seu Bubali.
Be more preferably, in step (1), every 100kg Rhizoma Arisaematis adds bile 380kg.
Be more preferably, every 100kg Semen Coicis rice water 38kg in step (2).
Be more preferably, in step (5), the amount of Chinese liquor is 14 times of 13 taste Chinese crude drug gross weights.
Be more preferably, in step (5), the number of degrees of Chinese liquor are 56 degree.
Be more preferably, soak 26 days in step (5).
Be more preferably, in step (5), wine liquid leaves standstill 10 hours.
Rheumatic arthritis expelling wind and dampness medicated wine preparation provided by the invention is convenient.In addition, excellent results of the present invention also shows:
1, formed by the meticulous compatibility of the pure Chinese herbal medicine of multi-flavor, absorb rapidly, thus realize the effects such as expelling wind and removing dampness, liver-regulating and kidney-nourishing, promoting blood circulation to remove obstruction in the collateral, expelling cold and relieving exterior syndrome, promoting the flow of QI-blood by warming the meridian, dissipating blood stasis for subsidence of swelling, bone and muscle strengthening, reach the object of curing rheumatic arthritis;
2, treatment cost is low, alleviates the financial burden of patient;
3, evident in efficacy, hurtless measure, have no side effect, alleviate the misery of patient;
4, treating both the principal and the secondary aspects of a disease at the same time, not easily recurs;
5, the property of medicine is stablized, safe and effective.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Radix Puerariae: base is former: be the dry root of legume pueraria lobata.Practise and claim Herba Gelsemii Elegantis.Dry.The property of medicine: sweet, pungent, cool.Return spleen, stomach warp.Function cures mainly: expelling pathogenic factors from muscles for reducing heat, promotes the production of body fluid, rash, yang invigorating antidiarrheal.For fever caused by exogenous pathogens headache, stiff nape and back, thirsty, quench one's thirst, measles without adequate eruption, hematodiarrhoea, has loose bowels, hypertension neck pain.
Rhizoma Chuanxiong: base is former: be the dry rhizome of samphire Rhizoma Chuanxiong.The property of medicine: pungent, temperature.Return liver, gallbladder, pericardium channel.Function cures mainly: blood-activating and qi-promoting, wind-expelling pain-stopping.For menoxenia, amenorrhea dysmenorrhea , mass in the abdomen is suffered from abdominal pain, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.
Herba Begoniae Laciniatae: base is former: be the herb of Begoniaceae plant Begonia pedatifida.The property of medicine: sweet, sour, cold.Function cures mainly: heat-clearing and toxic substances removing, dissipating blood stasis for subsidence of swelling.Main cough due to lung-heat, furuncle carbuncle, dysmenorrhea, amenorrhea, beriberoid pyretic arthralgia, treating swelling and pain by traumatic injury, Serpentis flood dragon hinders.
Herba Euonymi Bungeani: base is former: be root, the bark of Celastraceae vegetable silk Populus deltoides.The property of medicine: bitter, pungent, cool.Return liver,spleen,kidney warp.Function cures mainly: expelling wind and removing dampness, promoting blood circulation to remove obstruction in the collateral, removing toxic substances hemostasis.Main air wet arthritis, lumbago, traumatic injury wound is swollen, thromboangiitis obliterans, lung abscess, epistaxis, furuncle toxic swelling.
Semen Coicis: have another name called Semen Coicis, Semen Coicis, NLIUGU, base is former: be the kernel of grass Semen Coicis.The property of medicine: sweet light, be slightly cold, nontoxic.Return spleen, stomach, lung, large intestine channel.Function cures mainly: clearing away heat-damp and promoting diuresis, except rheumatism, and diuresis, lung benefiting evacuation of pus, strengthening the spleen and stomach, bone and muscle strengthening.Cure mainly rheumatism general pain, hygropyretic beriberi, damp and hot muscular contracture contracture, arthralgia chiefly caused by damp pathogen, edema, lung withers lung abscess, coughs vomiting bloody pus, sore throat carbuncle, acute appendicitis pyretic stranguria.
Radix Dipsaci: base is former: be the root of herbaceos perennial Radix Dipsaci.The property of medicine: toil, tepor.Return liver, kidney channel.Function cures mainly: invigorating the liver and kidney, reuniting the fractured tendons and bones, blood circulation regulating.Control aching pain in waist and back, the foot and knee being feeble, vaginal bleeding during pregnancy, metrorrhagia, leukorrhagia, seminal emission, traumatic injury, incised wound, anal fistula, carbuncle skin ulcer swells.
Ramulus Cinnamomi: base is former: be the twig of canella Cortex Cinnamomi.Ramulus Cinnamomi is containing volatile oil 0.69%, and in oil, main component is cinnamic aldehyde 64.75%, also has benzyl benzoate, cinnamyl acetate, β-cadinene, Chang Pu alkene, coumarin etc.The property of medicine: acrid, sweet, warm.Return bladder, the heart, lung meridian.Function cures mainly: expelling cold and relieving exterior syndrome, promoting the flow of QI-blood by warming the meridian.For activating YANG and prormoting functioning of QI exterior syndrome due to wind-cold, arthralgia due to cold-dampnes, extreme cold of the limbs, amenorrhea dysmenorrhea , mass in the abdomen lumps, the thoracic obstruction, cardiopalmus, phlegm retention, dysuria.
Rhizoma Arisaematis: base is former: be the tuber of aroid Rhizoma Arisaematis, arisaema amurense Maxim or Arisaema heterophyllum B1. etc.Chemical analysis: containing cupreol-D-Glucose glycoside and aminoacid.Pharmacological action: Rhizoma Arisaematis has antitumor action.The property of medicine: bitter, pungent, temperature, poisonous.Return lung, liver, spleen channel.Function cures mainly: drying dampness to eliminate phlegm, expelling wind for relieving convulsion, dispersing swelling and dissipating binds.Control middle wind-phlegm to mould, facial hemiparalysis, hemiplegia, epilepsy, infantile convulsion, tetanus, dizziness due to wind-phlegm, sore throat, scrofula, carbuncle, falls and flutters injured, snake bite and insect sting.The processed goods that Rhizoma Arisaematis (bile system) is Rhizoma Arisaematis and animal bile.
Fructus Arctii: base is former: be the dry mature fruit of feverfew Fructus Arctii.The property of medicine: pungent, bitter, cold.Attach to the lung and stomach meridians.Function cures mainly: dispelling wind and heat pathogens, lung qi dispersing rash, resolving toxin and disinhibiting the throat.For anemopyretic cold, cough with copious phlegm, measles, rubella, laryngopharynx swelling and pain, cheek erysipelas of itching, carbuncle sore tumefacting virus.
Herba Melastomatis Dodecandri: base is former: be the herb of Melastomateae plants Herba Melastomatis Dodecandri.Chemical analysis: leaf is containing tannin 7.40%, and fruit is containing tannin 2.02%.The property of medicine: " Luchuan book on Chinese herbal medicine ": " sweet in the mouth is micro-puckery, and property is slightly cool." " east, Fujian book on Chinese herbal medicine ": " enter liver,kidney,spleen, lung four warp." function cures mainly: promoting blood circulation and hemostasis, heat-clearing and toxic substances removing.Control dysmenorrhea, puerperal abdonimal pain, metrorrhagia, leukorrhagia, have blood in stool, dysentery, carbuncle, furuncle.
Herba seu Radix Calanthes: base is former: be herb or the rhizome of the orchid family Calanthe plant calanthe.Composition: fresh rhizome is containing indoles and glucosides thereof: calanthe glycosides A, B, dihydro phenanthrene derivative, indican, the luxuriant and rich with fragrance alcohol of calanthe, Ryukyu's calanthe glycosides; Indoles alkaloid class: couroupitine A, indirubin etc.The property of medicine: pungent, micro-hardship, is slightly cold.Function cures mainly: heat-clearing and toxic substances removing, promoting blood circulation and stopping pain.Cure mainly carbuncle, laryngopharynx swelling and pain, hemorrhoid, rheumatic arthralgia, traumatic injury.
Jujube nucleus: another name Semen Ziziphi Spinosae, Fructus Choerospondiatis, Semen Ziziphi Spinosae are Rhamnaceae plant Ziziphi Spinosae dry mature seed.The property of medicine: sweet, sour, flat.Return liver, gallbladder, heart channel.Function cures mainly: tonifying liver, mind calming, and arresting sweating promotes the production of body fluid.For restlessness of asrhenia type and insomnia, palpitation with fear dreaminess, the empty hyperhidrosis of body, Tianjin wound is thirsty.Semen Ziziphi Spinosae (parched): get clean Semen Ziziphi Spinosae, put in pot to fry with slow fire and to heave to crust and be micro-yellow, taking-up, cools.
Herba Cirrohopetali Andersonii: base is former: be the herb of the orchid family volume lobe epidendrum comb cap volume lobe orchid.Composition: herb is containing bibenzyl composition: the blue bibenzyl of volume lobe is surely peaceful, large aspidistra phenol, and the blue bibenzyl of volume lobe is fixed, and the blue bibenzyl of volume lobe is peaceful, batatasins; Also containing luxuriant and rich with fragrance constituents: volume lobe Lan Feiding, volume lobe Lan Feiling.The property of medicine: temperature, sweet, nontoxic.Function cures mainly: expelling wind and removing dampness, invigorates blood circulation, cough-relieving, helps digestion long-pending.Cure mainly rheumatic arthralgia, traumatic injury, cough is spitted blood, food stagnation, asthenia.
embodiment 1rheumatic arthritis expelling wind and dampness medicated wine, the primary raw material medicine getting following weight parts is prepared from (every part is 60g): Radix Puerariae 20 parts, Rhizoma Chuanxiong 10 parts, Herba Begoniae Laciniatae 9 parts, Herba Euonymi Bungeani 9 parts, Semen Coicis 10 parts, Radix Dipsaci 9 parts, Ramulus Cinnamomi 9 parts, Rhizoma Arisaematis (bile system) 8 parts, Fructus Arctii 10 parts, Herba Melastomatis Dodecandri 8 parts, Herba seu Radix Calanthes 10 parts, Semen Ziziphi Spinosae (stir-fry) 15 parts, Herba Cirrohopetali Andersonii 9 parts.
The preparation method of above-mentioned rheumatic arthritis expelling wind and dampness medicated wine is:
(1) by Arisaema Cum Bile levigation, put into cylinder, add Fel Sus domestica, every 100kg Rhizoma Arisaematis adds Fel Sus domestica 280kg, wets as degree, weather exposure to mixing, and to being degree without bad smell, not faling apart, drying, be ground into fine powder so that hand rubbing is agglomerating;
(2) get Semen Coicis rice water and mix leaching, every 100kg Semen Coicis rice water 32kg, to inhale profit for degree, even medicine and rice water together enter fried dry in pot, are ground into fine powder;
(3) get clean Semen Ziziphi Spinosae, put in pot to fry with slow fire and to heave to crust and be micro-yellow, taking-up, cools, is ground into fine powder;
(4) all the other the 10 taste medical materials except Rhizoma Arisaematis, Semen Coicis and Semen Ziziphi Spinosae are ground into end;
(5) step (1), step (2), step (3) and step (4) gained are mixed, enter cloth bag, put in tank, add Chinese liquor, the amount of Chinese liquor is 10 times of 13 taste Chinese crude drug gross weights, and the number of degrees of Chinese liquor are 50 degree, is placed on the sealing of sombre lucifuge place and soaks, every day stirs once, soak 20 days, filter medicinal residues, wine liquid leaves standstill 6 hours, filter, the wine liquid after filtration is stored in bottle.
The using method of rheumatic arthritis expelling wind and dampness medicated wine of the present invention: for oral administration, every day twice, each 20-30 milliliter; Also can external, dip medicinal liquid with rayon balls and embrocate affected part, every day embrocates 3-5 time.
embodiment 2rheumatic arthritis expelling wind and dampness medicated wine, the primary raw material medicine getting following weight parts is prepared from (every part is 60g): Radix Puerariae 40 parts, Rhizoma Chuanxiong 20 parts, Herba Begoniae Laciniatae 12 parts, Herba Euonymi Bungeani 15 parts, Semen Coicis 16 parts, Radix Dipsaci 18 parts, Ramulus Cinnamomi 16 parts, Rhizoma Arisaematis (bile system) 15 parts, Fructus Arctii 20 parts, Herba Melastomatis Dodecandri 12 parts, Herba seu Radix Calanthes 15 parts, Semen Ziziphi Spinosae (stir-fry) 30 parts, Herba Cirrohopetali Andersonii 16 parts.
The preparation method of above-mentioned rheumatic arthritis expelling wind and dampness medicated wine is:
(1) by Arisaema Cum Bile levigation, put into cylinder, add Fel Bovis seu Bubali, every 100kg Rhizoma Arisaematis adds Fel Bovis seu Bubali 450kg, wets as degree, weather exposure to mixing, and to being degree without bad smell, not faling apart, drying, be ground into fine powder so that hand rubbing is agglomerating;
(2) get Semen Coicis rice water and mix leaching, every 100kg Semen Coicis rice water 47kg, to inhale profit for degree, even medicine and rice water together enter fried dry in pot, are ground into fine powder;
(3) get clean Semen Ziziphi Spinosae, put in pot to fry with slow fire and to heave to crust and be micro-yellow, taking-up, cools, is ground into fine powder;
(4) all the other the 10 taste medical materials except Rhizoma Arisaematis, Semen Coicis and Semen Ziziphi Spinosae are ground into end;
(5) step (1), step (2), step (3) and step (4) gained are mixed, enter cloth bag, put in tank, add Chinese liquor, the amount of Chinese liquor is 16 times of 13 taste Chinese crude drug gross weights, and the number of degrees of Chinese liquor are 68 degree, is placed on the sealing of sombre lucifuge place and soaks, every day stirs once, soak 30 days, filter medicinal residues, wine liquid leaves standstill 12 hours, filter, the wine liquid after filtration is stored in bottle.
model case one:fourth XX, man, 26 years old.Main suit: " migrans arthralgia 1 year, facial edema January." history of present illness: patient started to occur finger-joint without obvious inducement before 1 year, knee joint, and carpal joint pain, can alleviate after activity.Without fear of cold, heating, without abdominal pain diarrhea, without uncomfortable in chest, cardiopalmus, without cough tachypnea.Go to a doctor in local private clinic, award treatment by Chinese herbs, symptom has no improvement.Since nearly one month, there is facial edema in patient, hypourocrinia, then comes to go to a doctor.Since morbidity, appetite is general, and sleep is normal, and stool is normal, and urine volume has reduced since nearly one month.Look into: T 36.9 DEG C, p 85bpm, r 23bpm, BP127/84mmHg, mind is clear, mental weariness.Joint is without red, and extremity muscular strength muscular tension is normal.Auxiliary examination: routine blood test: wbc4.0 × 10 9/ L, RBC3.59 × 10 12/ L, HB95g/L, neutral 72.5%, plt136 × 10 9/ L, routine urinalysis: normal.Electrocardiogram: sinus rate electrocardiogram, tuberculosis antibody: negative c reactive protein: 0.94mg/L, anti-O:75.9IU/ML, rheumatoid factor: 15.8IU/L, Immunoglobulin alpha 1 .82g/L, immunoglobulin G 15.99g/L, IgM 0.94g/L, complement component 3: 0.45g/L, complement 4:0.05g/L, antinuclear antibody: negative.Be diagnosed as rheumatic arthritis.Take the present embodiment gained rheumatic arthritis expelling wind and dampness medicated wine, every day twice, each 30 milliliters.Take 10 days, arthralgia obviously alleviates.Take 20 days, arthralgia disappears, and all diseases are eliminated, check, and indices is normal, recovery from illness.Follow up a case by regular visits to and do not recur.
embodiment 3rheumatic arthritis expelling wind and dampness medicated wine, the primary raw material medicine getting following weight parts is prepared from (every part is 60g): Radix Puerariae 25 parts, Rhizoma Chuanxiong 12 parts, Herba Begoniae Laciniatae 10 parts, Herba Euonymi Bungeani 11 parts, Semen Coicis 12 parts, Radix Dipsaci 12 parts, Ramulus Cinnamomi 11 parts, Rhizoma Arisaematis (bile system) 11 parts, Fructus Arctii 13 parts, Herba Melastomatis Dodecandri 9 parts, Herba seu Radix Calanthes 12 parts, Semen Ziziphi Spinosae (stir-fry) 19 parts, Herba Cirrohopetali Andersonii 11 parts.
The preparation method of above-mentioned rheumatic arthritis expelling wind and dampness medicated wine is:
(1) by Arisaema Cum Bile levigation, put into cylinder, add sheep bile, every 100kg Rhizoma Arisaematis adds sheep bile 300kg, wets as degree, weather exposure to mixing, and to being degree without bad smell, not faling apart, drying, be ground into fine powder so that hand rubbing is agglomerating;
(2) get Semen Coicis rice water and mix leaching, every 100kg Semen Coicis rice water 35kg, to inhale profit for degree, even medicine and rice water together enter fried dry in pot, are ground into fine powder;
(3) get clean Semen Ziziphi Spinosae, put in pot to fry with slow fire and to heave to crust and be micro-yellow, taking-up, cools, is ground into fine powder;
(4) all the other the 10 taste medical materials except Rhizoma Arisaematis, Semen Coicis and Semen Ziziphi Spinosae are ground into end;
(5) step (1), step (2), step (3) and step (4) gained are mixed, enter cloth bag, put in tank, add Chinese liquor, the amount of Chinese liquor is 12 times of 13 taste Chinese crude drug gross weights, and the number of degrees of Chinese liquor are 52 degree, is placed on the sealing of sombre lucifuge place and soaks, every day stirs once, soak 22 days, filter medicinal residues, wine liquid leaves standstill 8 hours, filter, the wine liquid after filtration is stored in bottle.
model case two:history XX, female, 54 years old.Patient's extremity and more than 10 years of back arthralgia, Changes in weather then pain exacerbates, and summer turns on the aircondition greedy cool all the year round, and cause arthralgia recurrence in recent years, migration is indefinite, and stride difficulty, breathes hard after activity, cardiopalmus, anorexia, metal fatigue, and chronognosis lower abdomen pain.Then come to go to a doctor.Examine and see: patient's floating pulse and slow, body of the tongue is light red, white and thin fur.Be diagnosed as rheumatic arthritis.Use the present embodiment gained rheumatic arthritis expelling wind and dampness medicated wine, dip medicinal liquid with rayon balls and embrocate affected part, embrocate 3 every day.After two weeks, pain symptom is obviously alleviated.Continue use 20 days, pain disappears, and all diseases are eliminated.Follow up a case by regular visits to and do not recur.
embodiment 4rheumatic arthritis expelling wind and dampness medicated wine, the primary raw material medicine getting following weight parts is prepared from (every part is 60g): Radix Puerariae 35 parts, Rhizoma Chuanxiong 16 parts, Herba Begoniae Laciniatae 11 parts, Herba Euonymi Bungeani 13 parts, Semen Coicis 15 parts, Radix Dipsaci 15 parts, Ramulus Cinnamomi 14 parts, Rhizoma Arisaematis (bile system) 14 parts, Fructus Arctii 16 parts, Herba Melastomatis Dodecandri 11 parts, Herba seu Radix Calanthes 14 parts, Semen Ziziphi Spinosae (stir-fry) 24 parts, Herba Cirrohopetali Andersonii 14 parts.
The preparation method of above-mentioned rheumatic arthritis expelling wind and dampness medicated wine is:
(1) by Arisaema Cum Bile levigation, put into cylinder, add Fel Bovis seu Bubali, every 100kg Rhizoma Arisaematis adds Fel Bovis seu Bubali 400kg, wets as degree, weather exposure to mixing, and to being degree without bad smell, not faling apart, drying, be ground into fine powder so that hand rubbing is agglomerating;
(2) get Semen Coicis rice water and mix leaching, every 100kg Semen Coicis rice water 43kg, to inhale profit for degree, even medicine and rice water together enter fried dry in pot, are ground into fine powder;
(3) get clean Semen Ziziphi Spinosae, put in pot to fry with slow fire and to heave to crust and be micro-yellow, taking-up, cools, is ground into fine powder;
(4) all the other the 10 taste medical materials except Rhizoma Arisaematis, Semen Coicis and Semen Ziziphi Spinosae are ground into end;
(5) step (1), step (2), step (3) and step (4) gained are mixed, enter cloth bag, put in tank, add Chinese liquor, the amount of Chinese liquor is 15 times of 13 taste Chinese crude drug gross weights, and the number of degrees of Chinese liquor are 60 degree, is placed on the sealing of sombre lucifuge place and soaks, every day stirs once, soak 28 days, filter medicinal residues, wine liquid leaves standstill 11 hours, filter, the wine liquid after filtration is stored in bottle.
model case three:woods XX, man, 20 years old.Main suit: more than migrans arthralgia half a year.Medical history: half a year how before, there is lumbago without beginning under obvious inducement in patient, activity is more very, after 5 days lumbago alleviate, pain and double knee joint, after be gradually developed to duplex joint, carpal joint and two ankle joint, in migrans, tender joint activity is unfavorable, without stiff phenomenon in obvious morning, time straight backache, cervical pain, limitation of activity of bending over, without uncomfortable in chest, cardiopalmus.Then come to go to a doctor.Check: double knee joint mild swelling, light tenderness, limb end Minor articulus is without deformity.Laboratory examination: anti-O:78.9IU/ML, ESR:92mm/h, RF (-).Heart Brightness Mode: Bicuspid valve slightly closes complete incomplete.Tcm diagnosis: arthromyodynia (migratory arthralgia).Western medicine diagnose: rheumatic arthritis.Take the present embodiment gained rheumatic arthritis expelling wind and dampness medicated wine, every day twice, each 20 milliliters.Take 10 days, symptom is clearly better.Continue to take 10 days, all diseases disappear, and do not recur so far.
embodiment 5rheumatic arthritis expelling wind and dampness medicated wine, the primary raw material medicine getting following weight parts is prepared from (every part is 60g): Radix Puerariae 32 parts, Rhizoma Chuanxiong 14 parts, Herba Begoniae Laciniatae 10.5 parts, Herba Euonymi Bungeani 12 parts, Semen Coicis 13 parts, Radix Dipsaci 14 parts, Ramulus Cinnamomi 12 parts, Rhizoma Arisaematis (bile system) 12 parts, Fructus Arctii 15 parts, Herba Melastomatis Dodecandri 10 parts, Herba seu Radix Calanthes 13 parts, Semen Ziziphi Spinosae (stir-fry) 22 parts, Herba Cirrohopetali Andersonii 12 parts.
The preparation method of above-mentioned rheumatic arthritis expelling wind and dampness medicated wine is:
(1) by Arisaema Cum Bile levigation, put into cylinder, add Fel Bovis seu Bubali, every 100kg Rhizoma Arisaematis adds Fel Bovis seu Bubali 380kg, wets as degree, weather exposure to mixing, and to being degree without bad smell, not faling apart, drying, be ground into fine powder so that hand rubbing is agglomerating;
(2) get Semen Coicis rice water and mix leaching, every 100kg Semen Coicis rice water 38kg, to inhale profit for degree, even medicine and rice water together enter fried dry in pot, are ground into fine powder;
(3) get clean Semen Ziziphi Spinosae, put in pot to fry with slow fire and to heave to crust and be micro-yellow, taking-up, cools, is ground into fine powder;
(4) all the other the 10 taste medical materials except Rhizoma Arisaematis, Semen Coicis and Semen Ziziphi Spinosae are ground into end;
(5) step (1), step (2), step (3) and step (4) gained are mixed, enter cloth bag, put in tank, add Chinese liquor, the amount of Chinese liquor is 14 times of 13 taste Chinese crude drug gross weights, and the number of degrees of Chinese liquor are 56 degree, is placed on the sealing of sombre lucifuge place and soaks, every day stirs once, soak 26 days, filter medicinal residues, wine liquid leaves standstill 10 hours, filter, the wine liquid after filtration is stored in bottle.
test example:in order to verify the drug effect of gained rheumatic arthritis expelling wind and dampness medicated wine (embodiment 5) of the present invention, We conducted contrast test.In January ,-2012 in January, 2009, screen 264 routine rheumatoid arthritis patients in 8 hospitals, wherein male 100 example, women 164 example, age 22-72 year, 47 years old mean age, the course of disease 5 months-12 years.Be divided into two groups at random, experimental group and matched group (often organizing 132 people).Experimental group male 50 example, women 82 example, age 22-72 year, 47 years old mean age, the course of disease 5 months-12 years.Matched group male 50 example, women 82 example, age 22-72 year, 47 years old mean age, the course of disease 5 months-12 years.Case takes random acquisition method, according to the rheumatism diseases diagnostic standard that U.S.'s rheumatology is issued for 1987.Experimental group uses products obtained therefrom of the present invention, using method: for oral administration, every day twice, each 20-30 milliliter; Also can external, dip medicinal liquid with rayon balls and embrocate affected part, every day embrocates 3-5 time.Matched group uses the medicine (as diclofenac sodium enteric-coated tablets, indomethacin ointment, piroxicam tablet, naproxen capsule etc.) of conventional therapy rheumatic arthritis.Criterion of therapeutical effect: with reference to Chinese Medical Association rheumatism meeting, tentative efficacy assessments in 1985 and national combination of Chinese and Western medicine rheumatism association curative effect determinate standard.Cure: clinical symptoms all disappears, and each joint part activity is as usual, anti-" O " and erythrocyte sedimentation rate are within normal range, and line is taken the photograph sheet prompting diseased region soft tissue inflammation swelling and disappeared; Effective: clinical symptoms obviously alleviates, each joint movement function recovers substantially, and anti-" O " and erythrocyte sedimentation rate are within normal range, and line is taken the photograph sheet prompting soft tissue inflammation swelling and disappeared; Take a turn for the better: clinical symptoms alleviates to some extent, and each joint movement function increases, anti-" O " and erythrocyte sedimentation rate decline to some extent and alleviate, and line is taken the photograph the large portion of sheet prompting soft tissue inflammation swelling and disappeared; Invalid: after treatment, the state of an illness is without improvement person.Total effectively comprising cures and effective.Treat after 25 days, result is as shown in table 1.
Table 1: gained rheumatic arthritis expelling wind and dampness medicated wine compliance test result of the present invention [example (%)]
Therapeutic effect: in 132 routine patients of experimental group, cures 95 examples, accounts for 71.97%; Effective 34 examples, account for 25.76%; Take a turn for the better 2 examples, accounts for 1.51%; Invalid 1 example, account for 0.76%, total effective rate reaches 97.73%.Successful is better than matched group.
The present invention is formed by the meticulous compatibility of the pure Chinese herbal medicine of multi-flavor.In side, Radix Puerariae expelling pathogenic factors from muscles for reducing heat, promotes the production of body fluid, rash, yang invigorating antidiarrheal.Rhizoma Chuanxiong blood-activating and qi-promoting, wind-expelling pain-stopping.Herba Begoniae Laciniatae's heat-clearing and toxic substances removing, dissipating blood stasis for subsidence of swelling.Herba Euonymi Bungeani expelling wind and removing dampness, promoting blood circulation to remove obstruction in the collateral, removing toxic substances hemostasis.Semen Coicis clearing away heat-damp and promoting diuresis, except rheumatism, diuresis, lung benefiting evacuation of pus, strengthening the spleen and stomach, bone and muscle strengthening.Radix Dipsaci invigorating the liver and kidney, reuniting the fractured tendons and bones, blood circulation regulating.Ramulus Cinnamomi expelling cold and relieving exterior syndrome, promoting the flow of QI-blood by warming the meridian.Rhizoma Arisaematis drying dampness to eliminate phlegm, expelling wind for relieving convulsion, dispersing swelling and dissipating binds.Fructus Arctii dispelling wind and heat pathogens, lung qi dispersing rash, resolving toxin and disinhibiting the throat.Herba Melastomatis Dodecandri promoting blood circulation and hemostasis, heat-clearing and toxic substances removing.Herba seu Radix Calanthes heat-clearing and toxic substances removing, promoting blood circulation and stopping pain.Jujube nucleus tonifying liver, mind calming, arresting sweating, promotes the production of body fluid.Herba Cirrohopetali Andersonii expelling wind and removing dampness, invigorates blood circulation, cough-relieving, helps digestion long-pending.All medicines share, and have the effects such as expelling wind and removing dampness, liver-regulating and kidney-nourishing, promoting blood circulation to remove obstruction in the collateral, expelling cold and relieving exterior syndrome, promoting the flow of QI-blood by warming the meridian, dissipating blood stasis for subsidence of swelling, bone and muscle strengthening, for treatment rheumatic arthritis Be very effective.
Finally it should be noted that, embodiment is the detailed description of the invention of optimum of the present invention, be not limited to the present invention, although with reference to previous embodiment to invention has been detailed description, for a person skilled in the art, it still can be modified to the technical scheme described in foregoing embodiments, or carries out equivalent replacement to wherein portion of techniques feature.Within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.

Claims (10)

1. rheumatic arthritis expelling wind and dampness medicated wine, is characterized in that, takes off the primary raw material medicine stating weight proportion and is prepared from: Radix Puerariae 20-40, Rhizoma Chuanxiong 10-20, Herba Begoniae Laciniatae 9-12, Herba Euonymi Bungeani 9-15, Semen Coicis 10-16, Radix Dipsaci 9-18, Ramulus Cinnamomi 9-16, Rhizoma Arisaematis (bile system) 8-15, Fructus Arctii 10-20, Herba Melastomatis Dodecandri 8-12, Herba seu Radix Calanthes 10-15, Semen Ziziphi Spinosae (stir-fry) 15-30, Herba Cirrohopetali Andersonii 9-16.
2. rheumatic arthritis expelling wind and dampness medicated wine as claimed in claim 1, is characterized in that, take off the primary raw material medicine stating weight proportion and be prepared from: Radix Puerariae 25-35, Rhizoma Chuanxiong 12-16, Herba Begoniae Laciniatae 10-11, Herba Euonymi Bungeani 11-13, Semen Coicis 12-15, Radix Dipsaci 12-15, Ramulus Cinnamomi 11-14, Rhizoma Arisaematis (bile system) 11-14, Fructus Arctii 13-16, Herba Melastomatis Dodecandri 9-11, Herba seu Radix Calanthes 12-14, Semen Ziziphi Spinosae (stir-fry) 19-24, Herba Cirrohopetali Andersonii 11-14.
3. rheumatic arthritis expelling wind and dampness medicated wine as claimed in claim 1, is characterized in that, take off the primary raw material medicine stating weight proportion and be prepared from: Radix Puerariae 32, Rhizoma Chuanxiong 14, Herba Begoniae Laciniatae 10.5, Herba Euonymi Bungeani 12, Semen Coicis 13, Radix Dipsaci 14, Ramulus Cinnamomi 12, Rhizoma Arisaematis (bile system) 12, Fructus Arctii 15, Herba Melastomatis Dodecandri 10, Herba seu Radix Calanthes 13, Semen Ziziphi Spinosae (stir-fry) 22, Herba Cirrohopetali Andersonii 12.
4. the preparation method of the rheumatic arthritis expelling wind and dampness medicated wine as described in as arbitrary in claims 1 to 3, it is characterized in that, step is as follows:
(1) by Rhizoma Arisaematis levigation, put into cylinder, add bile, every 100kg Rhizoma Arisaematis adds bile 280-450kg, wets as degree, weather exposure to mixing, and to being degree without bad smell, not faling apart, drying, be ground into fine powder so that hand rubbing is agglomerating;
(2) get Semen Coicis rice water and mix leaching, every 100kg Semen Coicis rice water 32-47kg, to inhale profit for degree, even medicine and rice water together enter fried dry in pot, are ground into fine powder;
(3) get clean Semen Ziziphi Spinosae, put in pot to fry with slow fire and to heave to crust and be micro-yellow, taking-up, cools, is ground into fine powder;
(4) all the other the 10 taste medical materials except Rhizoma Arisaematis, Semen Coicis and Semen Ziziphi Spinosae are ground into end;
(5) step (1), step (2), step (3) and step (4) gained are mixed, enter cloth bag, put in tank, add Chinese liquor, the amount of Chinese liquor is 10-16 times of 13 taste Chinese crude drug gross weights, the number of degrees of Chinese liquor are 50-68 degree, and be placed on the sealing of sombre lucifuge place and soak, every day stirs once, soak 20-30 days, filter medicinal residues, wine liquid leaves standstill 6-12 hour, and (preferred, wine liquid leaves standstill 8-11 hour; Be more preferably, wine liquid leaves standstill 10 hours), filter, the wine liquid after filtration is stored in bottle.
5. the preparation method of rheumatic arthritis expelling wind and dampness medicated wine as claimed in claim 4, is characterized in that, the bile added in step (1) is Fel Bovis seu Bubali, Fel Sus domestica or sheep bile (bile preferably added is Fel Bovis seu Bubali).
6. the preparation method of rheumatic arthritis expelling wind and dampness medicated wine as claimed in claim 4, is characterized in that, in step (1), every 100kg Rhizoma Arisaematis adds the preferred every 100kg Rhizoma Arisaematis of bile 300-400kg(and adds bile 380kg).
7. the preparation method of rheumatic arthritis expelling wind and dampness medicated wine as claimed in claim 4, is characterized in that, every 100kg Semen Coicis rice water 35-43kg(preferably every 100kg Semen Coicis rice water 38kg in step (2)).
8. the preparation method of rheumatic arthritis expelling wind and dampness medicated wine as claimed in claim 4, is characterized in that, in step (5), the amount of Chinese liquor is 12-15 times (amount of preferred Chinese liquor is 14 times of 13 taste Chinese crude drug gross weights) of 13 taste Chinese crude drug gross weights.
9. the preparation method of rheumatic arthritis expelling wind and dampness medicated wine as claimed in claim 4, is characterized in that, in step (5), the number of degrees of Chinese liquor are 52-60 degree (number of degrees of preferred Chinese liquor are 56 degree).
10. the preparation method of rheumatic arthritis expelling wind and dampness medicated wine as claimed in claim 4, is characterized in that, soaks 22-28 days (preferably soaking 26 days) in step (5).
CN201510003786.7A 2015-01-06 2015-01-06 Wind-damp clearing medicinal liquor for rheumatic arthritis and preparation of medicinal liquor Pending CN104491586A (en)

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AU2009101061A4 (en) * 2009-10-21 2010-02-25 G & W Aust Pty Ltd Herbal compositions and topical uses for relief of arthritic pain and joint inflammation
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